Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000849.1:
Cluster 1Other11710

BGC0000849, gamma-butyrolactone biosynthetic gene cluster from Streptomyces coelicolor. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: SCB1
SMILES string: Copy to clipboard
Molecular formula: C13H24O4
Exact molecular mass: 244.32726 Da (Other)
Molecular activity: Signalling
Molecular target: SCO6265

Class-specific details

Biosynthetic class(es):
Other biosynthetic class:

Gene cluster description

gamma-butyrolactone (BGC0000849). Gene Cluster 1. Biosynthetic class = Other. GenBank AL645882, positions 6890528-6948414. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Knock-out studies, Proven expression in natural host, Sequence-based prediction
Contact for this cluster:Eriko Takano (University of Manchester)

Literature references

1. Bentley SD et al. (2002) Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature 417(6885):141-7. doi: 10.1038/417141a.
2. Redenbach M et al. (1996) A set of ordered cosmids and a detailed genetic and physical map for the 8 Mb Streptomyces coelicolor A3(2) chromosome. Mol Microbiol 21(1):77-96.