BGC0000861 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000861 (Shewanella sp. BR-2)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	hglE-KS,PUFA	1	20,498	eicoseicosapentaenoic acid	Other	21%

BGC0000861 - Region 1 - PUFA,hglE-KS

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Location: 1 - 20,498 nt. (total: 20,498 nt) Show pHMM detection rules used

Region on contig edge.

hglE-KS: (hglE or hglD)
PUFA: PUFA_KS

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 20,499
Label		BGC0000861

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000861.1	2.00	Other	eicosapentaenoic acid	Shewanella sp. BR-2
BGC0000862.1	0.91	Other	eicosapentaenoic acid	Shewanella pneumatophori
BGC0000865.1	0.58	Other	eicoseicosapentaenoic acid	Photobacterium profundum SS9
BGC0000864.1	0.58	Other	eicosapentaenoic acid-like compound	Moritella marina ATCC 15381
BGC0001144.1	0.50	Polyketide	neosartoricin B	Trichophyton tonsurans CBS 112818
BGC0000863.1	0.47	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000056.1	0.47	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000284.1	0.46	Polyketide	phenolic lipids	Azotobacter vinelandii DJ
BGC0001404.1	0.42	Polyketide	sorbicillin	Penicillium rubens Wisconsin 54-1255
BGC0001872.1	0.41	Polyketide	fabclavine-polyamine	Xenorhabdus bovienii SS-2004

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000861.1	1.00	Other	eicosapentaenoic acid	Shewanella sp. BR-2
BGC0000862.1	0.76	Other	eicosapentaenoic acid	Shewanella pneumatophori
BGC0000865.1	0.63	Other	eicoseicosapentaenoic acid	Photobacterium profundum SS9
BGC0000864.1	0.63	Other	eicosapentaenoic acid-like compound	Moritella marina ATCC 15381
BGC0001144.1	0.59	Polyketide	neosartoricin B	Trichophyton tonsurans CBS 112818
BGC0000863.1	0.57	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000056.1	0.57	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000284.1	0.56	Polyketide	phenolic lipids	Azotobacter vinelandii DJ
BGC0001404.1	0.54	Polyketide	sorbicillin	Penicillium rubens Wisconsin 54-1255
BGC0001872.1	0.53	Polyketide	fabclavine-polyamine	Xenorhabdus bovienii SS-2004

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 20498:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

pfaA

PKS_AT (607..925): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 70.8%; 2-Rhyd-Malonyl-CoA: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 91.8
inactive: 33.3
Methoxymalonyl-CoA: 30.3
Methylmalonyl-CoA: 20.3
fatty_acid: 19.1
Isobutyryl-CoA: 12.0
CHC-CoA: 10.8
Propionyl-CoA: 4.1
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

pfaB

PKS_AT (344..661): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0