BGC0000864 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000864 (Moritella marina ATCC 15381)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T1PKS,hglE-KS,PUFA	1	41,587	High	eicosapentaenoic acid-like compound	other:other

BGC0000864 - Region 1 - PUFA,T1PKS,hglE-KS

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Location: 1 - 41,587 nt. (total: 41,587 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
hglE-KS: (hglE or hglD)
PUFA: PUFA_KS

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 41,588
Label		BGC0000864

Tailoring functions

Oxidoreductases: dehydrogenase

BAA89391.1: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: acetyltransferase acylase

BAA89375.1: acetyl-CoA acetyltransferase

smcogs: SMCOG1124: acetyl-CoA acetyltransferase

BAA89385.1: malonyl CoA-acyl carrier protein transacylase

smcogs: SMCOG1021: malonyl CoA-acyl carrier protein transacylase

Hydrolases: hydrolase

BAA89376.1: asparagine synthase (glutamine-hydrolyzing)

smcogs: SMCOG1177: asparagine synthase (glutamine-hydrolyzing)

Ligases: synthase

BAA89382.2: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

BAA89384.1: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000864.3	2.96	other (other)	eicosapentaenoic acid-like compound	Moritella marina ATCC 15381
BGC0000862.3	0.89	other (other)	eicosapentaenoic acid	Shewanella pneumatophori
BGC0000863.3	0.88	other (other)	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000861.5	0.86	other (other)	eicosapentaenoic acid	Shewanella sp. BR-2
BGC0002648.2	0.86	PKS	eicosapentaenoic acid	Shewanella sp. N2AIL
BGC0001257.3	0.86	PKS	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0001276.3	0.85	PKS	6-methylsalicyclic acid	Aspergillus terreus
BGC0001164.3	0.78	PKS	1-heptadecene	Cyanothece sp. PCC 7822
BGC0001160.5	0.78	PKS	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0000869.5	0.73	other (other)	heterocyst glycolipids	Nostoc sp. 'Peltigera membranacea cyanobiont'

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000864.3	1.00	other (other)	eicosapentaenoic acid-like compound	Moritella marina ATCC 15381
BGC0000862.3	0.63	other (other)	eicosapentaenoic acid	Shewanella pneumatophori
BGC0000863.3	0.63	other (other)	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000861.5	0.62	other (other)	eicosapentaenoic acid	Shewanella sp. BR-2
BGC0002648.2	0.62	PKS	eicosapentaenoic acid	Shewanella sp. N2AIL
BGC0001257.3	0.62	PKS	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0001276.3	0.62	PKS	6-methylsalicyclic acid	Aspergillus terreus
BGC0001164.3	0.59	PKS	1-heptadecene	Cyanothece sp. PCC 7822
BGC0001160.5	0.59	PKS	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0000869.5	0.58	other (other)	heterocyst glycolipids	Nostoc sp. 'Peltigera membranacea cyanobiont'

Similar known clusters from MIBiG 4.0

Module view

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Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 41587:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 0 - 40723:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 846 - 41587:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

BAA89382.2: mal

PKS_AT (604..904): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 89.6
inactive: 40.8
Methoxymalonyl-CoA: 24.8
Methylmalonyl-CoA: 24.0
CHC-CoA: 17.7
fatty_acid: 14.3
Isobutyryl-CoA: 13.9
Benzoyl-CoA: 11.9
trans-1,2-CPDA: 0.0
Propionyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

BAA89383.1: mxmal

PKS_AT (508..821): mxmal

ATSignature: (unknown)

No matches above 50%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 10.4
Isobutyryl-CoA: 8.8
trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

Link to PARAS substrate predictor