LOCUS       BGC0000869             17945 bp    DNA     linear   BCT 15-AUG-2013
DEFINITION  Nostoc sp. 'Peltigera membranacea cyanobiont' glycolipid gene
            cluster, complete sequence.
ACCESSION   BGC0000869
VERSION     BGC0000869
KEYWORDS    .
SOURCE      Nostoc sp. 'Peltigera membranacea cyanobiont'
  ORGANISM  Nostoc sp. 'Peltigera membranacea cyanobiont'
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
            Nostoc.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:21:05
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..5445
                     /gene="hglE"
     CDS             1..5445
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (52-509). E-value:
                     1.4e-122. Score: 401.5. Matches aSDomain:
                     nrpspksdomains_hglE_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (634-932). E-value: 2e-66. Score:
                     216.2. Matches aSDomain: nrpspksdomains_hglE_PKS_AT.1"
                     /NRPS_PKS="Domain: PP-binding (1348-1416). E-value: 1e-09.
                     Score: 30.7. Matches aSDomain:
                     nrpspksdomains_hglE_PP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (1478-1547). E-value:
                     4.3e-10. Score: 31.9. Matches aSDomain:
                     nrpspksdomains_hglE_PP-binding.2"
                     /codon_start=1
                     /gene="hglE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hglE-KS: hglE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 108.6; E-value:
                     4.9e-33)"
                     /gene_kind="biosynthetic"
                     /note="heterocyst glycolipid synthase"
                     /product="HglE"
                     /protein_id="AGJ76601.1"
                     /sec_met_domain="hglE (E-value: 3.2e-240, bitscore: 785.4,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.5e-67, bitscore: 216.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.4e-11, bitscore:
                     31.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAYSIDTALAELESLINNCEQAVIKSIEGKQMKPEKPVSINRIN
                     RQLQHNPIAIVGMASLLPQARNLREYWQNIVNKIDCITDVPSTHWSVEDYYDPNPRTTE
                     DKTYCKRGGFLPEVDFNPMEFGIPPSILEVTDVSQLLSLVVAKEAMEDAGYGEKREFNR
                     EMVGVILGVAMAKQLGMPLSARLEYPIWEKALKSSGLSDEDTKKIVDKIKSAYVKWDEN
                     AFPGMLANVVAGRIANRLNFGGMNCVVDAACASSFGALKMAISELVEHRSDMMLTGGVD
                     TDNTIMAYISFSKTPAVSPSENVKPFDAKSDGMMLGEGIGMIVLKRLEDAERDNDKIYA
                     VIKGIGTSSDGRYKSIYAPRKEGQVKALERAYEDAGFSPATVGLMEAHGTGTMAGDPTE
                     FGSLKDYFDLHDEKKQHIALGSVKSQIGHTKAAAGAASLIKTALALHHKVLPPTINITE
                     PNPKLNIKTSSFYLNTETRPWIRPEGEAPRRAGVSSFGFGGTNYHVVLEEYEADQNAAY
                     RLHSDASEVLLFAPTVDQLLSKSEEILGKLRSRSDSAGVSPDALRHYSQLVNECKSQQI
                     PLSAARFGFVAENLEEACKLLQTSIDWLKLKGTAASWEHPQGIYYRASGMELGGKVVSL
                     FSGQGSQYLEMGRELVMNFPLMRRLHGYMDSLLIKDNLQPLSEIVFPHPVFGEAEKNVQ
                     IAALQRTEYAQPAIGVLSAGMYSILQQAGFKSDFVAGHSFGELTALWAAGVLSTEDYLF
                     LVKARGQAMAAPEDPDHDAGSMLAVKEDISKVEAVLRHFPQVAIANQNSPTQFVLAGPT
                     AEIARIKEALHEKGYTAVLLPVSAAFHTPLIAFAQKSFAIATKSVKFQSPKIPVYSNVT
                     SKQYPKEAQGIQKILESHLSNSVLFKQEIENIYAAGGTCFVEFGPRRILTNLVKDILGD
                     RPHITVSLNPSAQKNSDRSLREAVVQLRVIGLALNNLDPYQLPQTIPPIETKKTLNVRL
                     NGINYRSEKTKNAFALALQDGHKVTLPAPESSETAAPLFSSPGVTPTLAAIETNGHKKL
                     TPVMNGVTASVITQPEQQMNPVTLSQPVQESKMQPTPEKLTNYEQLLASLEYLLTQFQE
                     NQAENLQVHGTYLNHQMEYAKAFFQLMQQQNSLLSESKSTAETAKMKLVVMESLERSMM
                     QFHSQQGETLRIHEQYLQEQLEYTKSFFQLIQQEYSQIISGEGTTQLTEKLSNFTPFTT
                     EAPVPATTKIVESQPLPVTEPVAKNRLNVTQEPLPAAVEAVVETTVSPKTQSIASLLPT
                     PHFATVETVEPVVAPPVPVVEEPQAEVVVKISSPPVKEVVAEPAPTTAAPVSGATIDIV
                     DLDKNLLAITSDKTGYPVEMLEMDMDMEADLGIDSIKRVEILGALQEMYPNLPKPNLEE
                     LSEKRTIGQVVEYLQSHASKSITVEIAVHEVQPATEIAVEAVPVVEVVVAPEPSVVIAF
                     TPEPETATSDEFANLGETLLAITSDKTGYPVEMLELEMDMEADLGIDSIKRVEILGAMQ
                     EMYPNLPKPNIEELGDLRTIGQIVDYLQQLAGGEKKKSEPEFVQQQPPQLEHELEHNIQ
                     RHLVKLRSLPQPDYLDFTLPEGHIGLITDDGSLTTYKLTESLIEKGWKIVVISFPQSLI
                     AQQAPLPTGVTRVTLANLSEEHLQQQLQAIASHCGTIGAFIHLHPMFVGNHTGSISYNE
                     SEKAIVKHVFLMAKHLKPSLNEAAKHGRSCFCTVAHLDGAFGLEYKVNFGAIGAGLFGL
                     TKTLRWEWPKVFTRAIDLSPRLDAKQSVHNIIAELHDPNLYISEVGYGSQGRVTIIAD"
     source          1..17945
                     /country="Iceland: Keldnagil, Reykjavik"
                     /db_xref="taxon:414689"
                     /host="Peltigera membranacea LA-31632 (IINH)"
                     /mol_type="genomic DNA"
                     /organism="Nostoc sp. 'Peltigera membranacea cyanobiont'"
     misc_feature    1..17945
                     /note="glycolipid gene cluster; hgl"
     protocluster    1..17945
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[7504:12253]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7505..12253
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     protocluster    1..17945
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[0:12253]"
                     /cutoff="20000"
                     /detection_rule="(hglE or hglD)"
                     /neighbourhood="20000"
                     /product="hglE-KS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      1..12253
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(hglE or hglD)"
                     /neighbourhood="20000"
                     /product="hglE-KS"
                     /protocluster_number="2"
     cand_cluster    1..17945
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(hglE or hglD)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="hglE-KS"
                     /product="T1PKS"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..17945
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000869"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..17945
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="hglE-KS"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="(hglE or hglD)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     aSDomain        157..1527
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hglE_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="1.40E-122"
                     /label="hglE_PKS_KS.1"
                     /locus_tag="hglE"
                     /protein_end="509"
                     /protein_start="52"
                     /score="401.5"
                     /tool="antismash"
                     /translation="IAIVGMASLLPQARNLREYWQNIVNKIDCITDVPSTHWSVEDYYD
                     PNPRTTEDKTYCKRGGFLPEVDFNPMEFGIPPSILEVTDVSQLLSLVVAKEAMEDAGYG
                     EKREFNREMVGVILGVAMAKQLGMPLSARLEYPIWEKALKSSGLSDEDTKKIVDKIKSA
                     YVKWDENAFPGMLANVVAGRIANRLNFGGMNCVVDAACASSFGALKMAISELVEHRSDM
                     MLTGGVDTDNTIMAYISFSKTPAVSPSENVKPFDAKSDGMMLGEGIGMIVLKRLEDAER
                     DNDKIYAVIKGIGTSSDGRYKSIYAPRKEGQVKALERAYEDAGFSPATVGLMEAHGTGT
                     MAGDPTEFGSLKDYFDLHDEKKQHIALGSVKSQIGHTKAAAGAASLIKTALALHHKVLP
                     PTINITEPNPKLNIKTSSFYLNTETRPWIRPEGEAPRRAGVSSFGFGGTNYHVVLEEY"
     aSModule        157..4248
                     /complete
                     /domains="nrpspksdomains_hglE_PKS_KS.1"
                     /domains="nrpspksdomains_hglE_PKS_AT.1"
                     /domains="nrpspksdomains_hglE_PP-binding.1"
                     /locus_tags="hglE"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       1153..1197
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hglE_0001"
                     /evalue="2.70E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="hglE"
                     /protein_end="399"
                     /protein_start="384"
                     /score="10.4"
                     /tool="antismash"
                     /translation="MEAHGTGTMAGDPTE"
     CDS_motif       1258..1302
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hglE_0002"
                     /evalue="2.60E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="hglE"
                     /protein_end="434"
                     /protein_start="419"
                     /score="10.5"
                     /tool="antismash"
                     /translation="GSVKSQIGHTKAAAG"
     aSDomain        1903..2796
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hglE_PKS_AT.1"
                     /evalue="2.00E-66"
                     /label="hglE_PKS_AT.1"
                     /locus_tag="hglE"
                     /protein_end="932"
                     /protein_start="634"
                     /score="216.2"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFSGQGSQYLEMGRELVMNFPLMRRLHGYMDSLLIKDNLQPLSEI
                     VFPHPVFGEAEKNVQIAALQRTEYAQPAIGVLSAGMYSILQQAGFKSDFVAGHSFGELT
                     ALWAAGVLSTEDYLFLVKARGQAMAAPEDPDHDAGSMLAVKEDISKVEAVLRHFPQVAI
                     ANQNSPTQFVLAGPTAEIARIKEALHEKGYTAVLLPVSAAFHTPLIAFAQKSFAIATKS
                     VKFQSPKIPVYSNVTSKQYPKEAQGIQKILESHLSNSVLFKQEIENIYAAGGTCFVEFG
                     PRRILTNLVKDILGDRP"
     CDS_motif       1906..1950
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hglE_0003"
                     /evalue="3.60E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="hglE"
                     /protein_end="650"
                     /protein_start="635"
                     /score="16.4"
                     /tool="antismash"
                     /translation="FSGQGSQYLEMGREL"
     CDS_motif       2179..2289
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hglE_0004"
                     /evalue="4.00E-13"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="hglE"
                     /protein_end="763"
                     /protein_start="726"
                     /score="41.4"
                     /tool="antismash"
                     /translation="DFVAGHSFGELTALWAAGVLSTEDYLFLVKARGQAMA"
     aSDomain        4045..4248
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hglE_PP-binding.1"
                     /evalue="1.00E-09"
                     /label="hglE_PP-binding.1"
                     /locus_tag="hglE"
                     /protein_end="1416"
                     /protein_start="1348"
                     /score="30.7"
                     /tool="antismash"
                     /translation="LLAITSDKTGYPVEMLEMDMDMEADLGIDSIKRVEILGALQEMYP
                     NLPKPNLEELSEKRTIGQVVEYL"
     aSDomain        4435..4641
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hglE_PP-binding.2"
                     /evalue="4.30E-10"
                     /label="hglE_PP-binding.2"
                     /locus_tag="hglE"
                     /protein_end="1547"
                     /protein_start="1478"
                     /score="31.9"
                     /tool="antismash"
                     /translation="TLLAITSDKTGYPVEMLELEMDMEADLGIDSIKRVEILGAMQEMY
                     PNLPKPNIEELGDLRTIGQIVDYL"
     gene            5589..7316
                     /gene="hglG"
     CDS             5589..7316
                     /NRPS_PKS="Domain: PKS_KR (11-235). E-value: 5.1e-49.
                     Score: 158.5. Matches aSDomain:
                     nrpspksdomains_hglG_PKS_KR.1"
                     /codon_start=1
                     /gene="hglG"
                     /note="KR domain protein"
                     /product="HglG"
                     /protein_id="AGJ76602.1"
                     /transl_table=11
                     /translation="MTQTAQLSPSSVFVVSGGAKGITAECTIRLAQQQPCKFILLGRSE
                     LLETEPDFAQNSDDSALKKCIMENLLSLGEKPTPMNVQKIYNKITSSREIKKTLAAIEK
                     TGAKAEYISVDVTDTQALQEKLATAVQYLGPITGIIHGAGNLADKLIEKKTEEDFEKVY
                     TAKVQGLENLLACVNPNQLQHLVLFSSVTGFYGNPGQSDYAIANEILNKSAHIFKQTYP
                     SCHVVAINWGAWDSGMVTAELKKIFQERKIDIIPIAVGAQMLVKEMDNTNHATAQVVIG
                     SPLVPMAAELDSELRTYRIRRQMTLEANPFLHDHTIAGSPVLPATCAMTWIINASEQLY
                     PGYRLFYYQDFKVLKGITFNETLAKEHILEIEEISKVNLESIDLKAKISSKNPEGKTHF
                     HFSAQLHLQREIPDAPIYESLNLEPDNIITATGKAFYQNGGATLFHGPGFQEVKRVLNI
                     SPEKITTECLWPELSAQQQGQFPVQWVNPYTTDLSMHALWIWTQHFHEEGCLPGKVEKF
                     EQFEAIPHNETFYVSCEVLAKTPSSAIANFIIHDRQGKIYSRMLGAHAIIWSMKMLRS"
     aSDomain        5622..6293
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hglG_PKS_KR.1"
                     /evalue="5.10E-49"
                     /label="hglG_PKS_KR.1"
                     /locus_tag="hglG"
                     /protein_end="235"
                     /protein_start="11"
                     /score="158.5"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="VFVVSGGAKGITAECTIRLAQQQPCKFILLGRSELLETEPDFAQN
                     SDDSALKKCIMENLLSLGEKPTPMNVQKIYNKITSSREIKKTLAAIEKTGAKAEYISVD
                     VTDTQALQEKLATAVQYLGPITGIIHGAGNLADKLIEKKTEEDFEKVYTAKVQGLENLL
                     ACVNPNQLQHLVLFSSVTGFYGNPGQSDYAIANEILNKSAHIFKQTYPSCHVVAINWGA
                     WD"
     CDS_motif       5625..5720
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hglG_0001"
                     /evalue="4.60E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="hglG"
                     /protein_end="44"
                     /protein_start="12"
                     /score="12.9"
                     /tool="antismash"
                     /translation="FVVSGGAKGITAECTIRLAQQQPCKFILLGRS"
     CDS_motif       6132..6230
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hglG_0002"
                     /evalue="1.60E-12"
                     /label="PKSI-KR_m4"
                     /locus_tag="hglG"
                     /protein_end="214"
                     /protein_start="181"
                     /score="39.9"
                     /tool="antismash"
                     /translation="LQHLVLFSSVTGFYGNPGQSDYAIANEILNKSA"
     CDS_motif       6519..6569
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hglG_0003"
                     /evalue="1.50E-04"
                     /label="PKSI-DH_m2"
                     /locus_tag="hglG"
                     /protein_end="327"
                     /protein_start="310"
                     /score="14.5"
                     /tool="antismash"
                     /translation="FLHDHTIAGSPVLPATC"
     gene            7505..12253
                     /gene="hglC"
     CDS             7505..12253
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (3-449). E-value:
                     2.9e-85. Score: 278.5. Matches aSDomain:
                     nrpspksdomains_hglC_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (466-923). E-value:
                     4.3e-73. Score: 238.4. Matches aSDomain:
                     nrpspksdomains_hglC_PKS_KS.2"
                     /NRPS_PKS="Domain: PKS_AT (1085-1361). E-value: 1.2e-18.
                     Score: 59.3. Matches aSDomain:
                     nrpspksdomains_hglC_PKS_AT.1"
                     /codon_start=1
                     /gene="hglC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hglE-KS: hglD"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     tra_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 63; E-value:
                     3.4e-19)"
                     /gene_kind="biosynthetic"
                     /note="beta-ketoacyl synthase"
                     /product="HglC"
                     /protein_id="AGJ76603.1"
                     /sec_met_domain="hglD (E-value: 7.6e-189, bitscore: 616.2,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 2.1e-77, bitscore: 249.6,
                     seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.5e-19, bitscore: 59.3,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKIAIIALSCLFPDAKNPEEYWQNIVHQKDSTSSATVEEIGVDP
                     TIFHNPVKGTPDKTYSLKGGYIRNFQFNPSEYNLPSEFVAGLDNTFKWSLYAAKQAIVQ
                     SGYWGNQNVLAKCGVILGNLSFPTKLSNQLFSPIYQQAINPAVRELLQYEDFNLAVPSA
                     TKASLYNAMISGLPASIVAQALSLSQINLCLDAACSSSFYAIKLASHYLWSHKADVMLA
                     GAISCADSLFVRMLFSGVQGYAENGISRPLDKSSRGLIPADGVGMVMLKRYSDAVRDGD
                     NILATICGNGLSNDGKGKHLLSPNPKGQVLAFERAYNEAKFSPKSIDYLECHATGTLLG
                     DTTEFNSIETFFGQNQAAPLVGSAKANTGHLLTAAGMVGLTKVILSMSHGVIPATMNVS
                     EPLTSEKGTISADKIVRTATIWPNNNAPIKRAAISAFGFGGTNSHLILEQGNTTESVES
                     TPPVPPTKIAIVGMDAFFGNCNGLDAFERSIYDGTQHFTSLPPQRWHGIENQKSVLKEY
                     GLADGKAPVGAYIKDFEIDTLSCKIPPNEIEKLNPQQLLLLKVSDRAVKDAKLQEGGNV
                     AVIVAAETEFSVHQLEQRWNLSWQVKDGLLNQGISLPAEHLSQLETIVKDSIHQPVEIG
                     EYVSHIANIMASRISALWNFTGPAFTVSTGENSALKALEVAQMLLATGEVDAVVVGAVD
                     LAGGVENVLFRSQFAPINTGVNTLGYDQQANGWTVGEGAGAVVLKRYEAAKEDNERIYA
                     VIDAMSFAQGNSTLSEAPVKPDASAISDVCKQAFEMAEIQPTEVNYVEVFGSGVPQEDE
                     AEITGLLQAYPKVGNGLHCALGSVKANIGHTYTASGIASLIKTALCLYYRYIPATPKWS
                     GVKTPQVWEGSPFYVAMESRPWFVDKGGTRRIAAINSMGIDGSYAHLILSEEPSQEERD
                     NRYLQQMPFHLFPIAVSDRTTIPDLLNNLQHTIEASSSLSATASETFATFQQHSHPKYV
                     LSITGRNTKDLLKEIESARKGVNNAFENGTDWQTPLGSYFTAKPLGKTGSVAYVYPAAV
                     NSYIGIGRTVFRLFPKVFEDLKSNNLYNRAADVEKLVYPRSLPKLTTRQLETLEKQLLD
                     DSLAMFESEIAFARYMTAIFRDDFKVKPQSVFGYSLGETSMMVAQGVWSDFEGGSNTLN
                     SSPLFGDKLSGPKNAVREYWGLTDSPNNNFWNTYVLMATPSQVRECLKHENHVYLTQIN
                     TPEEVLIAGEDAACKRVIATLGCNAFPAPFDHVIHCEAMRSQYEEIKKVNTLPSQNLPG
                     IVFYSAADYQPVALERDAIAHNIAKGLCQELDFPQLVNRVYDDGVKIFLEAGAGSVCSR
                     WIDKILGNKEHITVSLNRRGMDDHASMVKALAKLLSHQVNVDLSPLYNKAQESANSSKA
                     TLRTVTLGGKAIAATILSEENRKLVENFAGDLRSERFKIQHPDIPNVQQSEITDYLNTS
                     NQITQQENYSPNILPQPEEVKPKNIIDNVFQPREQLQSSESSAIRQPIPVFSPPVRTKK
                     ISSIISMFDLNKTQYQKLNANNSKITKAHTAFLQARQDYSQQMSEIIQLQLACAQNLLN
                     EES"
     aSDomain        7514..8851
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hglC_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="2.90E-85"
                     /label="hglC_PKS_KS.1"
                     /locus_tag="hglC"
                     /protein_end="449"
                     /protein_start="3"
                     /score="278.5"
                     /tool="antismash"
                     /translation="IAIIALSCLFPDAKNPEEYWQNIVHQKDSTSSATVEEIGVDPTIF
                     HNPVKGTPDKTYSLKGGYIRNFQFNPSEYNLPSEFVAGLDNTFKWSLYAAKQAIVQSGY
                     WGNQNVLAKCGVILGNLSFPTKLSNQLFSPIYQQAINPAVRELLQYEDFNLAVPSATKA
                     SLYNAMISGLPASIVAQALSLSQINLCLDAACSSSFYAIKLASHYLWSHKADVMLAGAI
                     SCADSLFVRMLFSGVQGYAENGISRPLDKSSRGLIPADGVGMVMLKRYSDAVRDGDNIL
                     ATICGNGLSNDGKGKHLLSPNPKGQVLAFERAYNEAKFSPKSIDYLECHATGTLLGDTT
                     EFNSIETFFGQNQAAPLVGSAKANTGHLLTAAGMVGLTKVILSMSHGVIPATMNVSEPL
                     TSEKGTISADKIVRTATIWPNNNAPIKRAAISAFGFGGTNSHLILEQ"
     CDS_motif       8588..8632
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hglC_0001"
                     /evalue="2.90E-01"
                     /label="PKSI-KS_m6"
                     /locus_tag="hglC"
                     /protein_end="376"
                     /protein_start="361"
                     /score="5.0"
                     /tool="antismash"
                     /translation="GSAKANTGHLLTAAG"
     aSDomain        8903..10273
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hglC_PKS_KS.2"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="4.30E-73"
                     /label="hglC_PKS_KS.2"
                     /locus_tag="hglC"
                     /protein_end="923"
                     /protein_start="466"
                     /score="238.4"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="IAIVGMDAFFGNCNGLDAFERSIYDGTQHFTSLPPQRWHGIENQK
                     SVLKEYGLADGKAPVGAYIKDFEIDTLSCKIPPNEIEKLNPQQLLLLKVSDRAVKDAKL
                     QEGGNVAVIVAAETEFSVHQLEQRWNLSWQVKDGLLNQGISLPAEHLSQLETIVKDSIH
                     QPVEIGEYVSHIANIMASRISALWNFTGPAFTVSTGENSALKALEVAQMLLATGEVDAV
                     VVGAVDLAGGVENVLFRSQFAPINTGVNTLGYDQQANGWTVGEGAGAVVLKRYEAAKED
                     NERIYAVIDAMSFAQGNSTLSEAPVKPDASAISDVCKQAFEMAEIQPTEVNYVEVFGSG
                     VPQEDEAEITGLLQAYPKVGNGLHCALGSVKANIGHTYTASGIASLIKTALCLYYRYIP
                     ATPKWSGVKTPQVWEGSPFYVAMESRPWFVDKGGTRRIAAINSMGIDGSYAHLILSEE"
     aSModule        8903..11587
                     /domains="nrpspksdomains_hglC_PKS_KS.2"
                     /domains="nrpspksdomains_hglC_PKS_AT.1"
                     /incomplete
                     /locus_tags="hglC"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       10004..10048
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hglC_0002"
                     /evalue="6.90E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="hglC"
                     /protein_end="848"
                     /protein_start="833"
                     /score="9.3"
                     /tool="antismash"
                     /translation="GSVKANIGHTYTASG"
     aSDomain        10760..11587
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hglC_PKS_AT.1"
                     /evalue="1.20E-18"
                     /label="hglC_PKS_AT.1"
                     /locus_tag="hglC"
                     /protein_end="1361"
                     /protein_start="1085"
                     /score="59.3"
                     /specificity="substrate consensus: mxmal"
                     /specificity="PKS signature: (unknown)"
                     /specificity="Minowa: mxmal"
                     /tool="antismash"
                     /translation="YPRSLPKLTTRQLETLEKQLLDDSLAMFESEIAFARYMTAIFRDD
                     FKVKPQSVFGYSLGETSMMVAQGVWSDFEGGSNTLNSSPLFGDKLSGPKNAVREYWGLT
                     DSPNNNFWNTYVLMATPSQVRECLKHENHVYLTQINTPEEVLIAGEDAACKRVIATLGC
                     NAFPAPFDHVIHCEAMRSQYEEIKKVNTLPSQNLPGIVFYSAADYQPVALERDAIAHNI
                     AKGLCQELDFPQLVNRVYDDGVKIFLEAGAGSVCSRWIDKILGNKEHITVSLNR"
     gene            12371..14134
                     /gene="pfaD"
     CDS             12371..14134
                     /codon_start=1
                     /gene="pfaD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 524.3; E-value: 7.1e-159)"
                     /gene_kind="biosynthetic-additional"
                     /note="PfaD family protein"
                     /product="PfaD"
                     /protein_id="AGJ76604.1"
                     /transl_table=11
                     /translation="MPSAPLRFVNRVNTLQLYHPLFVIRGITTVTTVDTVLSKHDNGLN
                     FSTWSYNKNQVWKGSLETVSFEKQTIKDKLMVLNKPCYIVKVAGKIGVTNEGYLSPGDN
                     GTTAQVELLTFAAPIRIQQFGDPNFLSSHGVKYAYVTGAMAGGIASEEMVIALGKEQIL
                     SSFGAGGLTPERLEAAINRIQQALPQGPYAFNLIHSPNEPAIERRAVDLYLKYQVRTVE
                     ASAFLDLTPNIVYYRVAGLGLNNANQIEIKNKIIAKISRREVATKFLQPAPARIIKELL
                     EQGLITELQATLAAKVPMADDITVEADSGGHTDNRPLVCVLPSIIALRDEIQAQYHYQT
                     PIRIGVAGGIGTPQSALAAFMMGAAYIMTGSINQSCVESGACEHTKKLLAQAEMADMIM
                     APAADMFEMGVKLQVLKRGTMFPMRAQKLFELYRAYDSIESIPLAEREKLEKQVFRKTI
                     AEVWEGTAAYLSQKNPEKLGKAVNNPKLKMALIFRWYLGLSSRWSSSGEKGREVDYQIW
                     CGPAMGGFNDWVRGSYLSEPNNRQVVDVANQIMTGAAFLYRVQNLKIQGLQTSDYYSQY
                     HPVRSTSLLEI"
     gene            14137..15651
                     /gene="hglB"
     CDS             14137..15651
                     /NRPS_PKS="Domain: ACP (17-83). E-value: 6.6e-13. Score:
                     40.7. Matches aSDomain: nrpspksdomains_hglB_ACP.1"
                     /NRPS_PKS="Domain: TD (134-374). E-value: 4e-87. Score:
                     283.3. Matches aSDomain: nrpspksdomains_hglB_TD.1"
                     /codon_start=1
                     /gene="hglB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047:phosphopantetheine-binding domain-containing
                     protein (Score: 69.1; E-value: 5e-21)"
                     /gene_kind="biosynthetic-additional"
                     /note="thioester reductase"
                     /product="HglB"
                     /protein_id="AGJ76605.1"
                     /sec_met_domain="PP-binding (E-value: 4.3e-13, bitscore:
                     38.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.2e-11,
                     bitscore: 33.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.1e-74, bitscore:
                     239.5, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIKQSFTADDIQVFLVSNLAKLLKVSTDEIDVKEHLENYGLDSA
                     QAMILVSNLEKLLGFQPSPLLLWHYPNIEALSQRLAEEVQEGSPVQDTKVVASNANTAP
                     SVLDLGAEAVLDPTIHPGAASNVLVGEPKNIFLTGGTGFLGAFIIRELLQETNADIYCL
                     VRAANAEEGKSKLQKNLEQYAIWQEEFNSRIIPIVGDLSQPLLGIGSEQFQILAGNIDT
                     IYHSAALLNYVFPYSALKAANVLGTQEVLRLACQIKVKPVHYVSSVAVFESTAYAGKVV
                     KEQDEFNHWEGIYLGYSQTKWVAEKLVKIARDRGLPVTIHRPPLISGDSKTGICNTHDF
                     INLMTKGCLQMGYFPDVDYMLDMSPVDYVSKAIVYLSRQKESIGKAFNLQHPQPAALKM
                     LVEWIRSFGYSVEMIPYEKWQSELINNVTSADNPLYTLRPFLLERWSDEQLTIPDLYLQ
                     ARRPHISCQDTLHALAGSSIACPPIDSQLFMTYTAYLIQSGFLNIA"
     aSDomain        14188..14385
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hglB_ACP.1"
                     /evalue="6.60E-13"
                     /label="hglB_ACP.1"
                     /locus_tag="hglB"
                     /protein_end="83"
                     /protein_start="17"
                     /score="40.7"
                     /tool="antismash"
                     /translation="SNLAKLLKVSTDEIDVKEHLENYGLDSAQAMILVSNLEKLLGFQP
                     SPLLLWHYPNIEALSQRLAEE"
     aSModule        14188..15258
                     /domains="nrpspksdomains_hglB_ACP.1"
                     /domains="nrpspksdomains_hglB_TD.1"
                     /final_module
                     /incomplete
                     /locus_tags="hglB"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        14539..15258
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hglB_TD.1"
                     /evalue="4.00E-87"
                     /label="hglB_TD.1"
                     /locus_tag="hglB"
                     /protein_end="374"
                     /protein_start="134"
                     /score="283.3"
                     /tool="antismash"
                     /translation="IFLTGGTGFLGAFIIRELLQETNADIYCLVRAANAEEGKSKLQKN
                     LEQYAIWQEEFNSRIIPIVGDLSQPLLGIGSEQFQILAGNIDTIYHSAALLNYVFPYSA
                     LKAANVLGTQEVLRLACQIKVKPVHYVSSVAVFESTAYAGKVVKEQDEFNHWEGIYLGY
                     SQTKWVAEKLVKIARDRGLPVTIHRPPLISGDSKTGICNTHDFINLMTKGCLQMGYFPD
                     VDYMLDMSPVDYVSKAIV"
     gene            16328..17131
                     /gene="sdr"
     CDS             16328..17131
                     /codon_start=1
                     /gene="sdr"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     154.7; E-value: 5.2e-47)"
                     /gene_kind="biosynthetic-additional"
                     /note="short-chain dehydrogenase/reductase SDR"
                     /product="SDR"
                     /protein_id="AGJ76606.1"
                     /transl_table=11
                     /translation="MNTTHQGRSKKTALITGAAGGIGYELACIFAAHDYNLVLVDRNGP
                     KLVEIAGKFQEKFGIFVKTIVKDLSISMAPEEIFTELQKADINVDVLVNNAGFGIHGLF
                     YETDLATELEMLQVNLVCLTHLTKLFVKGMVKQGDGKILNVASAAAFQPGPLMAVYFAT
                     KAYILSFSEAIANELEGTGVTVTVLCPGSTESGFHERTGMADSKLLKGKKMMDAKTVAE
                     VGFHALMKGKTIVIPGFMNKLLAKSVRFVPRNLVTKIVRNMQEDK"
     gene            complement(17235..17945)
                     /gene="hetI"
     CDS             complement(17235..17945)
                     /NRPS_PKS="Domain: ACPS (123-184). E-value: 1.3e-20. Score:
                     65.5. Matches aSDomain: nrpspksdomains_hetI_ACPS.1"
                     /codon_start=1
                     /gene="hetI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 212.7;
                     E-value: 6.7e-65)"
                     /gene_kind="biosynthetic-additional"
                     /note="4'-phosphopantetheinyl transferase"
                     /product="HetI"
                     /protein_id="AGJ76607.1"
                     /transl_table=11
                     /translation="MMNLWLPAPTDLTLLSDEIHVWRINLDQPEPHLQNLAATLSSDET
                     SRAERFYFQEHRQRFIAGRGILRTILGGYLGIQPSQVQFNYQQRGKPVLADTFADSGLE
                     FNLSHSQGLGLCAVNCTRPIGVDLEYIRPMSDLEALAKRFFLPREYDMLRSLSPNQQQE
                     VFFRYWTCKEAYLKATGDGLSQLEQIEVSLTPTEPAKLQISEDWSLFELLPADNYVAAV
                     AVENFGWHIKCWQY"
     aSDomain        complement(17394..17576)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hetI_ACPS.1"
                     /evalue="1.30E-20"
                     /label="hetI_ACPS.1"
                     /locus_tag="hetI"
                     /protein_end="184"
                     /protein_start="123"
                     /score="65.5"
                     /tool="antismash"
                     /translation="IGVDLEYIRPMSDLEALAKRFFLPREYDMLRSLSPNQQQEVFFRY
                     WTCKEAYLKATGDGLS"
ORIGIN
        1 atgtctgctt attcaattga tactgcctta gcagagttag aaagccttat aaacaattgt
       61 gaacaggctg tgattaagtc tatcgaggga aaacaaatga agccagagaa accagtgtca
      121 attaacagaa ttaacagaca attacaacac aatcctatcg ccattgttgg gatggcttct
      181 ctattacctc aagccagaaa tttacgggaa tactggcaaa atatagtaaa taaaattgac
      241 tgtattactg atgttccctc cactcactgg agcgtcgaag attattacga tcccaatcct
      301 agaacgactg aagataaaac ctactgtaaa agaggcgggt ttcttccaga ggttgatttt
      361 aacccgatgg aatttggcat accacctagc attttggaag tcacagatgt atcgcaacta
      421 ttaagtttag tggttgcgaa agaggcgatg gaagatgcgg gttatggcga aaagcgtgaa
      481 tttaaccgcg agatggttgg ggtaatctta ggcgtggcga tggccaagca attaggaatg
      541 ccactttctg ccaggttgga atatccgatt tgggaaaaag cgcttaaaag cagtggttta
      601 tctgacgaag ataccaaaaa aatcgttgat aaaatcaaaa gcgcttatgt gaagtgggat
      661 gagaacgctt tccccggaat gttagcaaat gtagtcgcgg gtagaattgc caaccgcctc
      721 aattttggcg ggatgaattg cgtagttgat gcggcttgtg ctagttcctt tggtgcttta
      781 aaaatggcaa tcagcgaact agttgagcat cgttctgata tgatgctgac tggtggtgtt
      841 gataccgata acaccatcat ggcttacatc tcgttcagca aaacaccggc ggtttctcct
      901 agtgaaaacg tcaaaccttt cgatgctaaa tccgatggga tgatgttggg tgaaggtatt
      961 gggatgattg tcctcaaacg tttggaagat gctgaacggg acaacgataa aatatatgcc
     1021 gtaattaaag gtattggtac ttccagcgat gggcgttata agagtattta tgctcctcgc
     1081 aaagaaggtc aagttaaagc cttagaacgc gcttacgaag atgccggctt ctctcccgct
     1141 actgttggtt tgatggaagc acatggtacc ggtacaatgg ctggagatcc gacagaattc
     1201 ggttctttaa aagactactt tgatctacat gatgagaaaa agcagcatat cgctttgggt
     1261 agtgtgaaat cacaaattgg acacacaaaa gcggctgcgg gtgcggcgag tttgattaaa
     1321 actgctttgg ctttacatca caaagtatta ccaccgacaa ttaatatcac tgagccaaac
     1381 cccaaactca acattaaaac ttcatccttt tatttgaata ccgaaactag accttggatt
     1441 cgtccagaag gagaagcgcc aagacgtgcg ggtgtaagtt ctttcggctt tggcggaacc
     1501 aactatcacg tcgttttgga agaatatgaa gccgaccaaa acgccgctta ccgcttacac
     1561 agtgatgcta gtgaagtgct gttgtttgct cctacagtag accaattgtt gagcaaatcg
     1621 gaagagattt taggtaagtt gcgttcacga agtgactccg caggagtatc gccagatgca
     1681 ctcagacact actcacaatt agtcaatgag tgcaaatcac aacaaattcc cctctctgct
     1741 gccagatttg ggtttgtagc cgagaatctg gaagaagctt gcaagttgct gcaaactagc
     1801 attgactggc tgaaactcaa aggaacagca gcatcttggg aacatcccca agggatttat
     1861 taccgcgctt ctggtatgga gttgggcgga aaagttgtct ccctattttc tggacaaggt
     1921 tcgcaatact tggagatggg acgcgaactg gtgatgaatt ttcctttgat gcgccgtctg
     1981 catggttata tggatagcct gttaatcaaa gataatttgc agccgctttc agaaatagtt
     2041 ttccctcatc ctgtgtttgg agaggcagaa aagaatgtcc aaattgctgc cttacaacgc
     2101 acagaatacg ctcaaccagc catcggggtg ttgagtgcag ggatgtacag catactgcaa
     2161 caagctgggt tcaagtcaga ttttgtggcg ggacatagct ttggtgaact aacagcgcta
     2221 tgggctgcgg gggttttgag tactgaagat tacttgttct tagtgaaagc taggggtcaa
     2281 gcaatggctg cacctgaaga tccggatcat gatgcgggta gtatgctggc tgtcaaagaa
     2341 gacatcagca aagtggaagc agtgctgaga cattttccgc aagttgcgat cgctaatcaa
     2401 aattccccaa ctcagtttgt cttggctggg cctaccgcag aaatagcgag aatcaaagag
     2461 gctttacacg agaaaggata tacagctgta ttgctacctg tttcagcagc tttccataca
     2521 ccgctaatcg cctttgctca gaaatcattt gcgatcgcca ccaagtctgt caaattccaa
     2581 agtcccaaaa tccctgttta cagcaacgtt accagtaagc agtatcccaa agaagcccaa
     2641 ggtattcaaa aaatcctcga aagccacctt tccaattcag tactgtttaa gcaggaaatt
     2701 gaaaatatct atgcagccgg tggtacttgc tttgtggaat ttgggccgag aagaattctc
     2761 accaacttag tcaaagatat ccttggcgat cgcccacaca tcactgtatc tctgaaccct
     2821 agcgctcaaa agaatagcga tcgctctttg cgagaagcag ttgtgcagtt gcgagtaatt
     2881 ggcttggctt tgaataacct cgatccttac caacttcccc aaactatacc cccaattgag
     2941 acgaagaaga cattaaatgt ccgtttaaac ggcatcaact acagatccga aaaaacgaaa
     3001 aatgccttcg ctctagcttt gcaggatggg cataaagtca cattacccgc ccccgaatct
     3061 tctgaaactg cggctccttt gtttagtagc cccggtgtaa ctccaactct cgcagcgatc
     3121 gagactaacg gacataaaaa acttacccca gtaatgaacg gtgtgactgc tagtgtcatc
     3181 acccagccag agcaacagat gaatcctgtt accctgtcac aaccagtcca ggaatctaag
     3241 atgcaaccaa caccagaaaa gctgacaaat tacgaacaac ttttagcaag tttagaatat
     3301 ctcctgacac agttccagga aaatcaagcc gagaatttac aagttcacgg tacttatctc
     3361 aaccatcaaa tggaatacgc taaagcgttt ttccaactga tgcaacagca gaattctttg
     3421 ttgagtgaaa gtaaatcaac agccgaaact gccaaaatga agctagttgt catggaaagc
     3481 ttagagcgta gcatgatgca gtttcattcc caacagggtg aaactctacg catccatgaa
     3541 caatatcttc aagagcagct ggaatatact aaaagctttt tccaactcat ccagcaagag
     3601 tattctcaaa ttatctctgg tgagggaaca actcaactta cagagaaact cagcaatttc
     3661 actccgttca ccacagaagc accagtaccc gccactacca agatagtaga aagccagcct
     3721 ttgcctgtaa ctgagcctgt agctaaaaat cgcttaaatg ttactcaaga gcctctcccg
     3781 gctgctgtag aggctgtagt tgaaactact gtatctccaa agacccaatc aatcgcgtct
     3841 ctacttccca caccgcattt cgccactgtc gagacggtag agcctgtagt cgcaccacct
     3901 gtcccagtag tagaagaacc ccaagctgag gttgtagtca aaattagctc acccccagtc
     3961 aaggaagttg ttgcagaacc agcacctaca actgctgcac ctgtatctgg cgcaaccatc
     4021 gatattgttg acttggataa aaacctctta gccatcacca gcgacaaaac cggctacccg
     4081 gtagagatgc tggaaatgga catggacatg gaggctgatt tagggattga ctctatcaaa
     4141 cgggtggaaa tcttaggggc gctacaagag atgtacccca acctacccaa gcccaattta
     4201 gaagaactgt cagaaaaacg caccatcggt caagttgtcg agtatctgca atcccacgct
     4261 tccaaaagta ttactgtaga aattgcagtt cacgaagtac aaccagcaac tgagattgca
     4321 gtagaggctg taccagtagt tgaggtagtc gttgcacctg aaccaagcgt agttatcgca
     4381 ttcaccccag aaccagaaac cgctacaagt gatgaatttg caaacttagg tgaaaccctg
     4441 ttagccatca ccagcgataa aactggctac ccagtcgaga tgctggaact ggaaatggac
     4501 atggaagccg acttagggat tgactcgatt aaacgggtgg aaatcttagg ggcgatgcaa
     4561 gaaatgtacc ccaacttacc taagccaaat atcgaagaac tcggcgatct ccgcacaatc
     4621 ggtcaaatag ttgattacct acagcagttg gctggaggtg aaaaaaaaaa gtctgaacct
     4681 gagtttgtcc aacagcagcc accccaatta gaacatgaac tagagcataa tatccagcgc
     4741 catctcgtca aactcagaag tctaccacag cccgattatt tggatttcac gttaccagag
     4801 ggacacatcg gtttaatcac cgatgatggt tccctcacca cttataaatt aactgaatcc
     4861 ttaatcgaga aaggctggaa aatagtagtt atcagcttcc cccaatcgct catcgcccag
     4921 caagcgcctt tacctacagg agtaacccgc gtcaccttag caaacttgag tgaagaacat
     4981 cttcaacaac aattgcaagc gatcgcatct cactgcggaa cgattggggc tttcatccat
     5041 ctacacccaa tgtttgtagg aaatcacacc gggagtattt cttataacga atcagaaaag
     5101 gcgatcgtca agcacgtatt tttgatggcg aaacacctga aaccctccct taacgaagcc
     5161 gcaaagcatg gacgtagttg tttctgcaca gttgctcacc ttgatggagc cttcggttta
     5221 gagtacaaag tcaactttgg tgcgatcggc gctggtttat ttggattaac caaaactctg
     5281 agatgggaat ggccaaaagt tttcacccgt gcgatcgacc taagtcccag acttgacgct
     5341 aaacagtcag tacacaacat catcgccgaa cttcacgatc ccaaccttta tataagtgaa
     5401 gttggctacg gctcacaagg acgagtgact attatcgccg attaatctct tctctctgcg
     5461 ctctctgcgt ctctgtggtt cgtttaaaaa aaaccgcaga ggcgcagagg acacagagaa
     5521 agatataaga gagcatcttt taattacgaa ttacgaatta cgaattacga attaatccca
     5581 gaggatttat gacacaaaca gcccagctta gtccatcatc tgtctttgtt gtgagcggcg
     5641 gtgcaaaagg gattacggct gagtgtacta tcagattagc ccaacagcaa ccctgcaaat
     5701 tcatcctcct cggtcgctca gaactattag aaaccgagcc agattttgct caaaactccg
     5761 atgactccgc attgaaaaaa tgcatcatgg aaaaccttct ttctctagga gagaagccca
     5821 cacccatgaa tgtgcaaaaa atatataaca aaattacctc tagccgcgaa attaaaaaga
     5881 ctctagcagc aattgaaaaa actggagcta aagccgaata tatcagcgtc gatgtcacag
     5941 atacgcaagc tttacaagaa aaactagcca ctgctgtgca atatctcggc ccaattaccg
     6001 gaatcatcca cggcgcggga aacttagctg acaagttaat tgaaaagaaa acagaagagg
     6061 attttgaaaa agtttacacc gccaaagtac aaggtttaga aaacctccta gcttgcgtta
     6121 acccaaatca acttcagcat ttagttttgt tttcttcagt aaccggattt tacggaaatc
     6181 ccggacaatc tgattatgcg atcgcaaatg aaattctgaa caaatcagcc catatattta
     6241 agcaaactta tccctcatgt catgtagtcg ctatcaactg gggcgcttgg gacagtggga
     6301 tggtgacagc agaattaaag aagatttttc aagagcgaaa aatcgatata attcctattg
     6361 cagtcggggc acaaatgctc gttaaggaaa tggataatac caatcatgca accgcacaag
     6421 ttgtcattgg tagcccactt gtcccaatgg cggcggagtt agattcagaa ctgcgaacct
     6481 atcgtatccg tcgccaaatg acattagagg ctaatccatt tttgcacgat catactattg
     6541 ctggttctcc agttttacca gcaacttgtg caatgacctg gattatcaat gcttctgagc
     6601 aattatatcc tggttatcgg ttgttttatt accaagattt caaagttttg aaagggatta
     6661 cttttaatga aacattagcg aaggaacata tattagaaat agaagaaatt tctaaagtta
     6721 atcttgaaag tatcgacctt aaagccaaaa tttccagtaa aaaccctgaa ggaaaaaccc
     6781 attttcattt tagcgctcaa ctccatcttc agcgtgaaat cccagatgca cccatctatg
     6841 aatctctcaa tctcgaacca gataatatca tcactgcgac aggaaaagct ttttaccaaa
     6901 atggtggggc tacattattt catggccccg gttttcaaga agttaagaga gttttaaata
     6961 tcagtcccga aaaaatcaca acagaatgtt tgtggccaga actcagcgca cagcaacaag
     7021 gacaattccc tgtccaatgg gtaaatcctt acaccactga cttgagtatg cacgccctat
     7081 ggatttggac acaacacttt catgaagaag gttgtttacc tggaaaagta gaaaaatttg
     7141 aacagtttga agcgatacca cataacgaaa cattttacgt ttcttgtgaa gtactagcta
     7201 agacaccaag tagtgcgatc gcaaacttta tcatacacga ccgccaaggt aaaatctatt
     7261 cacgaatgct cggcgctcat gccattattt ggtcaatgaa aatgctcaga agctaagaat
     7321 atatcaagtt taaagttcgt agtaaggact ttagtccttc ttaatataag cactaaagtg
     7381 cttactacaa actatcaaaa tcttaggatt gctataactt gcctcgttta aagtttgggg
     7441 aacagcgtaa atcctgcctt ttaattatct cttgctaaat acccaaactc ggagcatata
     7501 aatcgtggaa aaaatagcca tcatcgcatt atcatgccta ttccccgatg caaagaatcc
     7561 tgaagaatac tggcaaaata tcgttcatca aaaagattcg acatcctctg caaccgtcga
     7621 agaaatcgga gtagatccga caatatttca caatccagtt aaaggtacac cagacaaaac
     7681 ttattcactc aaaggcggat acatccgcaa cttccagttt aatccatctg aatacaatct
     7741 accatctgaa tttgttgctg gcttagataa caccttcaaa tggtcattgt atgccgctaa
     7801 acaagcaatt gtacaaagtg gttattgggg taatcaaaat gtcctggcaa aatgcggcgt
     7861 aattttaggt aatttgtcat tcccgacaaa attatctaac caattattct ctccaattta
     7921 tcagcaagct attaaccctg ctgttagaga acttttgcag tatgaagact ttaatttagc
     7981 tgtaccaagt gcaaccaaag cgtctttata caatgcaatg atatctggtt taccagcatc
     8041 tatcgtagct caagcactat ctctatccca gattaattta tgtctggatg ctgcttgttc
     8101 gtcatcattt tatgcgatta aactagcatc tcattactta tggtcacaca aagctgatgt
     8161 catgttagct ggagccataa gttgtgcaga ttccctattc gtgcggatgt tattttccgg
     8221 tgttcaagga tatgcagaaa acggcatcag ccgcccctta gataaatcct ctagagggct
     8281 aatccccgcc gatggtgttg ggatggtgat gctgaaaaga tattctgatg ccgttagaga
     8341 tggtgataat attctcgcca ctatctgcgg taatggactc tcgaatgatg gcaaaggtaa
     8401 gcacttactg agtccgaatc ctaaaggaca agttttagct tttgaacgag catacaatga
     8461 ggcgaaattt agtccaaaaa gcattgatta tctagagtgt cacgccactg gcacattact
     8521 aggagataca accgaattca attccatcga aacatttttt ggtcaaaatc aagctgctcc
     8581 tctggtgggt tctgccaaag caaatactgg tcacttgtta actgctgccg gcatggttgg
     8641 cttgactaaa gtgattttga gtatgtctca tggtgtaatt ccagcaacca tgaatgtttc
     8701 ggaaccttta acttcagaaa aaggtacaat ttccgccgat aaaattgtta gaacagctac
     8761 gatatggcct aataataacg caccaattaa acgggcagct attagcgctt ttggttttgg
     8821 cggcactaat tctcatctga ttttagaaca aggaaataca acagaatcag ttgaatcaac
     8881 tccacctgtt ccacctacaa aaattgccat tgtcggcatg gatgcctttt ttggtaactg
     8941 caatggctta gatgcttttg aacgcagtat ttatgatggg acacagcatt ttacttctct
     9001 accgcctcaa agatggcatg ggatagaaaa tcaaaagagt gtcctgaaag agtacggttt
     9061 agcagacggg aaagcaccag taggggcata tatcaaggat tttgaaatcg atactttatc
     9121 gtgcaaaatc ccaccgaatg aaatcgaaaa gttaaaccca caacaattat tactcctgaa
     9181 agttagcgat cgcgccgtaa aagatgcgaa actacaggaa ggcggcaatg tagcagttat
     9241 agtcgccgcc gagacagaat tctctgtaca tcagctagag caaagatgga atctatcttg
     9301 gcaagttaag gatggcttac tcaaccaagg aatttctcta cctgctgaac acctttccca
     9361 actggaaact atcgtcaaag atagcattca ccaaccagta gaaatcggcg aatatgtgag
     9421 tcacatcgcc aacatcatgg caagtcggat ttctgcttta tggaatttca ctggccctgc
     9481 attcactgtc agcactggcg aaaattctgc cctcaaagcc ttggaagttg cccaaatgct
     9541 actcgctacg ggagaagtag acgcggtggt tgtgggtgcg gtagatttag ccggtggtgt
     9601 ggaaaatgtc ttgttccgca gccaatttgc accaattaat acgggtgtca ataccttggg
     9661 ttatgaccaa caagccaatg gttggacggt tggcgaaggt gcgggtgctg tcgtcctcaa
     9721 gcgctacgag gctgctaagg aagataatga acgcatctat gcagtaattg atgccatgag
     9781 tttcgcacaa ggtaattcta ctttgagtga ggctccggta aaacctgatg cttcagctat
     9841 cagtgatgtc tgcaaacaag ctttcgagat ggctgagatt caacccacag aagttaacta
     9901 tgtggaagtc tttggtagcg gcgttcccca ggaggatgaa gccgaaatta caggtttact
     9961 ccaagcttat ccgaaagtgg gcaatggttt gcattgtgca ttgggcagcg tcaaagctaa
    10021 tatcggccac acctatacag catcgggaat tgctagctta atcaaaaccg ctctctgtct
    10081 ttattacagg tatattcccg ccacacccaa atggtctggt gtcaaaacac cgcaagtatg
    10141 ggaaggtagc cctttctatg tggcgatgga atcaagacct tggtttgtcg ataaaggcgg
    10201 cacacgcaga atagcagcaa ttaatagcat gggtatagat ggcagttacg cccatttaat
    10261 cttatcggag gaacccagcc aagaggagcg ggacaacaga tatttgcaac aaatgccttt
    10321 tcatctgttt ccgatagcag ttagcgatcg caccactatc cccgatcttc tcaacaatct
    10381 ccaacatacc atagaagcga gttcttcttt atcagctacc gccagcgaaa cattcgctac
    10441 ttttcaacag cattctcatc caaaatacgt cttatcaatt acaggacgta acacaaaaga
    10501 tttactcaaa gaaattgaat ctgcccgcaa aggtgtaaat aatgcttttg aaaacggcac
    10561 agattggcaa acaccactag gaagttattt cacagcaaaa ccattaggta aaactgggtc
    10621 agttgcttac gtttatcccg cagccgtcaa ttcttatatc ggcattggtc ggactgtttt
    10681 tcgcttattt ccgaaagttt tcgaggactt aaaaagtaac aatctctaca accgggctgc
    10741 tgatgttgaa aagttagttt atcccagaag tttacctaaa ttgacaacta ggcaactaga
    10801 aactctcgaa aagcaattgt tagatgattc actggcaatg tttgaaagtg aaatcgcctt
    10861 cgctagatac atgacagcaa ttttccgaga tgattttaaa gtcaagccgc aatctgtatt
    10921 tgggtatagc ttgggtgaaa ctagtatgat ggttgcccaa ggagtttgga gtgattttga
    10981 gggtggaagc aacaccttaa actcatcacc tctatttggc gataagttat ctgggcctaa
    11041 aaatgctgtg cgtgaatatt ggggattaac agattcacca aacaacaatt tttggaatac
    11101 ctatgttctc atggctactc catctcaagt tagagaatgc ctgaaacatg agaatcacgt
    11161 ctacttaact caaatcaaca caccagaaga agtattaatt gctggtgaag atgcagcctg
    11221 taagcgagtg attgcaactt taggttgcaa tgctttcccc gctcccttcg accatgtgat
    11281 acattgtgaa gcgatgcgat cgcagtacga ggaaatcaag aaggtaaaca ccttaccatc
    11341 gcaaaatctc cctggtattg tgttctattc agccgccgac tatcaaccag ttgcactcga
    11401 aagagatgcg atcgcgcata acatcgccaa aggattgtgt caagaacttg attttccgca
    11461 attggtaaat cgtgtctacg atgatggtgt gaaaatattt ctagaagcag gcgcaggtag
    11521 tgtttgttca cgatggattg ataaaattct cggcaacaaa gaacacatca cagtctctct
    11581 aaatcgtaga gggatggatg accatgcttc gatggtcaaa gcattagcaa aactactcag
    11641 tcatcaggtg aacgtggatt tatcaccgtt gtacaacaaa gctcaagaaa gtgctaattc
    11701 aagtaaagca acattgagaa cagttacctt gggtggaaaa gcgatcgctg ctacaatttt
    11761 gagcgaagaa aatcgtaaac ttgttgaaaa ttttgctggg gatcttagga gcgaacgttt
    11821 caaaatacag catccagata tacctaatgt ccaacaatct gaaatcacag attatcttaa
    11881 cacttccaac caaataaccc aacaagaaaa ttattcccct aacatcttgc ctcagccaga
    11941 agaagtaaaa ccgaaaaata tcattgataa cgtttttcaa ccgagagaac aattacaatc
    12001 ttctgagtca agcgcaatta gacagccaat tcctgttttc tctccacccg tcagaactaa
    12061 aaaaattagt agcatcatca gcatgttcga tttaaataag acccagtatc aaaagctcaa
    12121 tgctaataat tcaaagataa ctaaagcaca cactgccttc ttacaagcta gacaagatta
    12181 cagtcaacaa atgagcgaaa tcattcaatt gcaactagct tgcgcccaaa acttgcttaa
    12241 cgaagaatct taatatctca taccaattct ctctaaactt tctcttcctt cgcgcccttt
    12301 gcgtccttcg cggttcgttt aaaaattatt acgtgcatct ctcagagaat tggtattact
    12361 ctcttactct gtgccctctg cgcctctgcg gttcgttaac agagtcaaca cccttcaact
    12421 ttatcatcca ttgtttgtaa tccgagggat aactaccgtg acaaccgtag atacggtact
    12481 aagtaaacac gataatggtc ttaacttctc cacttggtct tataacaaaa accaagtttg
    12541 gaaaggttct ttagaaactg tatcttttga gaaacaaacc atcaaagata aattgatggt
    12601 gttaaataaa ccctgctaca tcgtgaaagt tgccggaaaa atcggtgtca ctaatgaggg
    12661 ttatttatcc cctggtgata atggcacaac agcacaagta gaactgctaa catttgcagc
    12721 cccaatccgc attcaacaat ttggagatcc gaattttctc tcctctcatg gagtaaaata
    12781 tgcctacgtt accggcgcaa tggctggcgg aattgcttcc gaagaaatgg tcattgcact
    12841 cggaaaagag caaattttga gttcctttgg tgcaggtggt ttaactccag aacgtttgga
    12901 agcagccata aatcgcattc aacaagcctt acctcaaggg ccctacgcat ttaatctaat
    12961 ccacagcccc aacgaacctg cgattgaacg tcgcgctgta gatttatacc tcaaatatca
    13021 agtgagaaca gtagaagcct ctgcatttct cgacttgacc cccaacattg tttattaccg
    13081 tgttgctgga ttgggtttga ataacgccaa tcaaattgaa atcaaaaata aaatcattgc
    13141 caaaatttct cgccgagaag ttgcaactaa atttctgcaa ccagcaccag cgagaataat
    13201 taaagaactc ctagaacaag ggttaattac tgagttacaa gcaactcttg cagctaaagt
    13261 tccgatggct gatgatatta ccgtcgaggc tgattctgga ggtcatacag ataaccgtcc
    13321 cttggtttgt gtgttacctt ctattattgc cttgcgagat gaaattcaag cccaatatca
    13381 ttatcaaaca ccaattagaa ttggcgtagc tggaggaatt gggacaccac aatcagcatt
    13441 agcagctttc atgatgggtg ctgcttatat aatgaccggt tccattaatc aatcatgcgt
    13501 tgaatctggg gcttgtgaac ataccaaaaa gttattagcc caagcagaaa tggctgatat
    13561 gataatggct ccagccgcag atatgtttga aatgggagtc aaattgcaag ttctcaaacg
    13621 gggtacaatg ttccccatgc gagcgcaaaa attatttgaa ctctaccgcg cttatgattc
    13681 cattgaaagc atcccccttg cagaaagaga gaaattagaa aaacaagttt ttcgcaaaac
    13741 tattgccgaa gtatgggaag gaactgcggc ttatttgtcc caaaagaatc ctgagaaact
    13801 tgggaaagca gtcaataatc ctaaactaaa aatggcgtta attttccgtt ggtatctagg
    13861 attatcttct cgctggtcta gttctggcga aaaaggtaga gaagtcgatt atcaaatttg
    13921 gtgtggcccg gcaatgggcg gtttcaatga ctgggtacgc ggttcctatc tttctgaacc
    13981 aaataatcgt caagtagttg atgttgctaa tcaaattatg actggtgcag cctttttgta
    14041 tcgtgtccaa aatttgaaaa ttcaaggact gcaaacttcc gattattaca gtcaatatca
    14101 ccctgttcgt tctacatcat tgttggagat ttaaaaatga ctataaaaca gtcttttaca
    14161 gcagacgaca ttcaagtatt tttagtatct aacttagcta agttactaaa agtatcaact
    14221 gatgaaatag atgtcaaaga acatttagaa aactatgggt tggattcagc ccaagcaatg
    14281 attctagtca gtaacttaga aaagttgctc ggatttcaac cctctccgtt gctgctgtgg
    14341 cattacccaa atattgaagc tctttcacag cgtttagctg aagaagtgca agaaggttcg
    14401 ccagttcaag atacaaaggt agtagcctct aatgccaaca ctgccccctc tgttctagat
    14461 ttaggtgctg aggctgttct tgaccccacc atccatcccg gtgctgcatc taatgtactt
    14521 gtgggtgaac ccaagaacat ctttttaact ggcggaacag gctttttagg agcctttatc
    14581 atccgggaat tgctacaaga aaccaatgcg gatatctatt gcttagtgcg tgctgctaat
    14641 gccgaagaag gcaaaagcaa actgcaaaaa aatctggaac agtatgcaat ttggcaagaa
    14701 gaatttaact ccagaattat tccgattgtc ggtgatttat ctcagccatt gttaggtatt
    14761 ggttcagaac agtttcaaat tttagctggc aatattgata ctatatatca tagtgctgct
    14821 ttgttgaatt atgtttttcc atactctgca ttgaaggcag ctaatgtttt aggcactcaa
    14881 gaagttttga gattagcttg tcaaattaaa gtcaagcctg tacattacgt ttctagtgtg
    14941 gctgtttttg aatccacagc ttatgctggc aaggttgtta aagaacagga tgaattcaat
    15001 cattgggaag gtatttatct tggctactca caaactaaat gggtagctga aaagttagtc
    15061 aaaattgctc gtgaccgtgg gcttcctgta actatccata gacccccact gatttcaggt
    15121 gatagcaaga caggtatttg taacacacat gactttatca atttgatgac aaaaggctgt
    15181 ctacaaatgg gatatttccc tgatgtagat tatatgttgg atatgtcacc tgtggactat
    15241 gtaagcaaag cgatcgttta tctatcacgt caaaaagaat ccataggtaa agctttcaat
    15301 ttacaacatc cccaacccgc tgctttgaaa atgctagttg agtggatacg ctcttttggt
    15361 tattcagttg aaatgatccc ctatgaaaaa tggcaatcag agttaatcaa taatgtcact
    15421 tctgctgaca atcctttata tactctgcgg ccatttttac tggaacgttg gtctgatgaa
    15481 caactgacta ttcctgattt gtacttacaa gctagaagac cccatattag ctgccaagat
    15541 actcttcatg cactagcagg tagttctatt gcgtgtcctc caattgattc tcaattgttt
    15601 atgacttata ccgcctactt gattcaaagt ggattcttga atatagctta ggaattcaca
    15661 acttgtgtag gatgttggaa aagtgtttgg ctgtgatttt aggcacttgg agatccccct
    15721 accccctctt aataaggatg ggataagaag ctctaaatcc cccttttaaa cggggattta
    15781 ggaggatatc taaatgttaa gaatgtaacg cactatcccg gatactttgg tgcgttacat
    15841 aaaccgtaac acaccctaca aaataatttt ttagtcaacg tttttagaac tcagtactac
    15901 tgaatagcca atatttcaga tgccagcaac aactcacata ctaacagtgg caatataatt
    15961 gccctgtttt ttatgctcaa taatgtaaat ttttagtatc cacctcttga cagaagcaat
    16021 cgaggataga atggttagtg tcgggcacaa aagtttgatt ttacctgctg gctcttgatt
    16081 agtcacaaaa accagcgcta gcagtttgaa ataaccaaac ttatttaatg ctcaacttct
    16141 tcgatgcata aatcctaagt ttgcgtttgg attgctacat ctatctaacg catcacacaa
    16201 gcatttgaaa gggtaataac ttaagatgtt tatcgtctgt tcaggtatta cacgcacttc
    16261 attgtagaac aagaaacact gtaaatgcaa cgcagcttca tcaagttgaa ttcaccaata
    16321 ttcttacatg aacacaacac atcaaggtcg gagcaaaaaa actgctctta ttactggggc
    16381 agctggtgga attgggtacg aattagcatg tatttttgct gctcatgatt acaatctggt
    16441 cttagtagac agaaacgggc caaagctagt agaaattgcg ggtaaattcc aagaaaaatt
    16501 tggaattttt gtcaaaacta ttgttaagga tttatctata tcaatggctc ctgaagaaat
    16561 tttcacggag ttgcaaaaag ccgatattaa tgttgatgtg ctggtaaata atgctggatt
    16621 tggtatacat ggattatttt acgaaacaga cctagctact gaattggaaa tgctacaggt
    16681 aaatttggtg tgtctcaccc atttaaccaa gctattcgtg aaggggatgg taaagcaagg
    16741 tgatggtaaa atattaaacg tcgcctcggc tgcggctttt caacctgggc ctttgatggc
    16801 agtttatttt gctactaaag cctatatctt atctttttca gaagcgatcg ctaatgaatt
    16861 agaaggtact ggtgtcactg tgacagttct ttgcccaggt tcaacagaat ctggctttca
    16921 tgagcgaact gggatggctg actctaagtt actcaagggc aagaagatga tggatgcaaa
    16981 aacagtagcc gaagttggtt ttcacgcctt aatgaagggc aaaaccattg tcattcctgg
    17041 ttttatgaat aaactacttg caaaaagcgt tagatttgta cctagaaacc tggtgacaaa
    17101 aattgtcaga aatatgcagg aggacaaata agtagattgt catttgtcat ttgtcattgg
    17161 tcattggtca ttggtcattt gataatgttg gcaaaatctc ttttatttca cccaggagat
    17221 gagcttaatc aaaattaata ttgccaacac tttatatgcc agccaaaatt ctctacagca
    17281 acagcagcaa cataattgtc agcaggcagt agttcaaaaa gactccagtc ttcagatatc
    17341 tgtaacttgg ctggttctgt gggagtgagc gacacttcaa tttgctctaa ctgggatagt
    17401 ccgtctccag ttgcttttaa ataagcttcc ttacaagtcc agtaacggaa aaatacctct
    17461 tgctgttggt tgggagatag cgatcgcaac atatcatatt ctctcggtaa aaagaaccgt
    17521 ttggcaagag cttccagatc ggacatcggg cgaatatatt ctaggtctac accaattggg
    17581 cgagtacaat tcaccgcaca caaacccaac ccttgagaat gagacaagtt aaactccagt
    17641 ccactgtcag caaatgtatc tgctaatact ggtttgccac gctgttgata attaaactgc
    17701 acttgtgacg gctggatacc taaatagcca cctaatatag ttcgcaggat accacgacca
    17761 gcgatgaaac gctgtcggtg ttcctgaaaa tagaaccgtt cagcacgaga tgtttcgtca
    17821 ctggaaagag ttgctgctaa attttgcaga tgtggttctg gttggtcaag gtttatgcgc
    17881 cagacatgaa tctcatctga taacaaagtt aaatctgtcg gtgcaggtag ccagagattc
    17941 atcat
//
