BGC0000869 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000869 (Nostoc sp. 'Peltigera membranacea cyanobiont')

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS,hglE-KS	1	17,945

BGC0000869 - Region 1 - T1PKS,hglE-KS

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Location: 1 - 17,945 nt. (total: 17,945 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
hglE-KS: (hglE or hglD)

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core biosynthetic genes

additional biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 17,946
Label		BGC0000869

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000869.1	2.00	Other	heterocyst glycolipids	Nostoc sp. 'Peltigera membranacea cyanobiont'
BGC0001144.1	0.52	Polyketide	neosartoricin B	Trichophyton tonsurans CBS 112818
BGC0000284.1	0.50	Polyketide	phenolic lipids	Azotobacter vinelandii DJ
BGC0001542.1	0.50	Polyketide	cercosporin	Cercospora zeina
BGC0000862.1	0.50	Other	eicosapentaenoic acid	Shewanella pneumatophori
BGC0001872.1	0.49	Polyketide	fabclavine-polyamine	Xenorhabdus bovienii SS-2004
BGC0000056.1	0.48	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000048.1	0.47	Polyketide	dothistromin	Dothistroma septosporum
BGC0000161.1	0.47	Polyketide	isoterrein	Aspergillus terreus NIH2624
BGC0000863.1	0.45	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000869.1	1.00	Other	heterocyst glycolipids	Nostoc sp. 'Peltigera membranacea cyanobiont'
BGC0001144.1	0.59	Polyketide	neosartoricin B	Trichophyton tonsurans CBS 112818
BGC0000284.1	0.58	Polyketide	phenolic lipids	Azotobacter vinelandii DJ
BGC0001542.1	0.58	Polyketide	cercosporin	Cercospora zeina
BGC0000862.1	0.58	Other	eicosapentaenoic acid	Shewanella pneumatophori
BGC0001872.1	0.58	Polyketide	fabclavine-polyamine	Xenorhabdus bovienii SS-2004
BGC0000056.1	0.57	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000048.1	0.57	Polyketide	dothistromin	Dothistroma septosporum
BGC0000161.1	0.57	Polyketide	isoterrein	Aspergillus terreus NIH2624
BGC0000863.1	0.56	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12

Similar known gene clusters

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 17945:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

hglE

PKS_AT (634..932): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 70.8%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 86.7
inactive: 32.0
Methoxymalonyl-CoA: 31.5
Methylmalonyl-CoA: 23.3
Isobutyryl-CoA: 15.1
CHC-CoA: 14.5
Propionyl-CoA: 12.2
fatty_acid: 11.2
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

hglC

PKS_AT (1085..1361): mxmal

ATSignature: (unknown)

No matches above 50%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 17.3
Isobutyryl-CoA: 12.4
trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0