LOCUS       BGC0000871              8807 bp    DNA     linear   BCT 31-JAN-2014
DEFINITION  Myxococcus xanthus DK 1622, complete genome.
ACCESSION   BGC0000871
VERSION     BGC0000871
KEYWORDS    .
SOURCE      Myxococcus xanthus DK 1622
  ORGANISM  Myxococcus xanthus DK 1622
            Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
            Cystobacterineae; Myxococcaceae; Myxococcus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 20:53:48
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1789112
            Orig. end    :: 1797919
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..1029)
                     /locus_tag="MXAN_1527"
     CDS             complement(1..1029)
                     /NRPS_PKS="Domain: NAD_binding_4 (53-176). E-value:
                     1.1e-13. Score: 42.7. Matches aSDomain:
                     nrpspksdomains_MXAN_1527_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 217;
                     E-value: 6.4e-66)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="MXAN_1527"
                     /note="identified by match to protein family HMM PF00106;
                     match to protein family HMM PF01073; match to protein
                     family HMM PF01370; match to protein family HMM PF02719;
                     match to protein family HMM PF04321; match to protein
                     family HMM PF05368; match to protein family HMM PF07993"
                     /product="NAD dependent epimerase/dehydratase family
                     protein"
                     /protein_id="ABF89140.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 1e-14, bitscore:
                     42.7, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.6e-08, bitscore:
                     21.7, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLLVTGGTGFLGTHLVPRLVAAGHEVRLIGRSRPSGAPYAGTEY
                     VPGDLKNRDAVRRALEGVDAVYHLAGLVSFQPKDARKMFELHVDSTRELLRDVREAGVK
                     RVVLASTSGTIAVSKEAHVRDESADYPITVVGQWPYYLSKIYEEKLALAYCRKHEIPLV
                     VLNPSLLMGPGDDRLSSTWTVVKFLNREIPAMPGGGISFVDARDAADAFVQALTRGEVY
                     GRHLMGVNLSMKDFFQRLERLSGVPAPKLKLPSKVNVLGGKLLERWAKVRGTTPTLDPQ
                     EIDIGEHWFWLDASKAEAELGFRARDIQETLSETVQHIYGKMPPQSLPGTKGRLAELRE
                     NT"
     subregion       1..8807
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="Other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..8807
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     aSDomain        complement(502..870)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MXAN_1527_NAD_binding_4.1"
                     /evalue="1.10E-13"
                     /label="MXAN_1527_NAD_binding_4.1"
                     /locus_tag="MXAN_1527"
                     /protein_end="176"
                     /protein_start="53"
                     /score="42.7"
                     /tool="antismash"
                     /translation="DAVRRALEGVDAVYHLAGLVSFQPKDARKMFELHVDSTRELLRDV
                     REAGVKRVVLASTSGTIAVSKEAHVRDESADYPITVVGQWPYYLSKIYEEKLALAYCRK
                     HEIPLVVLNPSLLMGPGDD"
     CDS_motif       complement(931..1020)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_1527_0001"
                     /evalue="4.10E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="MXAN_1527"
                     /protein_end="33"
                     /protein_start="3"
                     /score="9.8"
                     /tool="antismash"
                     /translation="LVTGGTGFLGTHLVPRLVAAGHEVRLIGRS"
     gene            complement(1026..5438)
                     /locus_tag="MXAN_1528"
     CDS             complement(1026..5438)
                     /NRPS_PKS="Domain: NAD_binding_4 (21-357). E-value: 2e-49.
                     Score: 159.7. Matches aSDomain:
                     nrpspksdomains_MXAN_1528_NAD_binding_4.1"
                     /NRPS_PKS="Domain: AMP-binding (568-998). E-value: 1.3e-99.
                     Score: 325.4. Matches aSDomain:
                     nrpspksdomains_MXAN_1528_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (1132-1191). E-value:
                     1.7e-10. Score: 33.2. Matches aSDomain:
                     nrpspksdomains_MXAN_1528_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     349.6; E-value: 4.1e-106)"
                     /gene_kind="biosynthetic"
                     /locus_tag="MXAN_1528"
                     /note="identified by similarity to GB:AAQ66826.1; match to
                     protein family HMM PF00501; match to protein family HMM
                     PF00550; match to protein family HMM PF01553; match to
                     protein family HMM PF07993"
                     /product="putative long-chain-fatty-acid CoA ligase"
                     /protein_id="ABF88003.1"
                     /sec_met_domain="AMP-binding (E-value: 9.7e-104, bitscore:
                     335.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-11, bitscore:
                     33.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.9e-50, bitscore:
                     159.7, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAALPELNVTQTFTGKRLLFAGATGFVGKVTLSMLLTRYGQDLDK
                     VYVLVRKGSAASAERRFFDKVATSEPFQPLRDSLGDEGALAFIRQKVEVLDGDITDPWM
                     GLEEPQVEALTGKVHAFINCAGLVSFNPSLEVGLNVNTHGLKFAAALAVRWSVPLIHMS
                     TAFVAGNRSGLVFEDEEVRGYFPKREEMDGRDFSLEQELQDAARIVARLREQAEDRALT
                     STFRKKALDRLEEEGRDPNDEKTLRLAVGRERKLWLSGELVRAGMERAAHWGWPNTYTY
                     TKSLGEQVLAATPGLRYSIVRPSIVESARHFPFPGWNEGFTTSAPLAFAGIKGPGGIPA
                     GENTILDIIPVDQVAGATIGITAHAMDVEERRIYQLASGDMNPFYAGRSVELVGLYRRR
                     YYRNRESGNALMNKLRSRVEPQPVSKKEFELFSAPMLSRGARFLKKAIDEVRPAWGAPA
                     VQAMLDKAKVSLDEVDDNAQGIIALTELFLPFLYENRYVFRCDNTRSVYARMAHADRLK
                     VPWDPEHIDWREYFLGTHLPGLEKWVFPGMESEREKRTVIPAHRDLLELMEATVHAYRH
                     RVAFRMVAGEKEERFTYGEVHRYAARVGSFLLAAGIKHGDRVLLVSENRPEWGISYFGI
                     LRAGATVVPVDPGLSEAELVNIARRADARACLVSEDAARDFPGLFAALGDGVTVASLAE
                     AMTGDPAHPDRIGPVRRSAAADDLASIIFTSGTTGTPKGVMLTHRNFAALVAKLAGTFD
                     IGVGDGVLSVLPLHHTFEFAAGFLTPFWRGAEITYIDELTSDRLGEVFETGRITAMVGV
                     PALWQLLHRKITQEFASRPPFIEQALKALMATHGELRNRNNINLGKLLFWPVHRKFGGR
                     IKVIVSGGSALPDDVHKAFHELGFNITEGYGLTEAAPVLAVTKPGNKRQPGTVGRALPG
                     IELRILNPDNDGLGEVLAKGPNVMPGYFGDREATEAVLKDGWLHTGDLGRLDAEGHLYL
                     VGRAKDVIIDHNGKNIYPDELEELYQDHTHIKELSIVGLPDDAGGEKVACLCVPDYADR
                     PREEVRRELEEHFRKVSAGMPFYRRVKVLRLWDGELPRTAKRSVKRKQVVEELKRQERM
                     AASASKAREKAANPTTGGIADWLFPLIADVSHRPVSDVRPDALLSGDLGFDSLMLTELS
                     SALEAAGVPLPAVEDLTQVQTVEDLRKVVASSGKRPTVETRAKEISKENERAEEVEIPV
                     PDVVADVGRQLLSFGQKVLYGGVFDVKVTGKSFIPQNRNFLVIANHSSHLDAGLVRVAL
                     GDQGERLVSLAARDYFFNTPLKRAWFENFTNLIPIERQGSLRESLRMAGEALRQGFNVL
                     IFPEGTRSTTGELMEFKSTLGYLALTFNMDVLPLYIGGAFDALPKGSVLPKTKTPLRVN
                     IGPALGHADLRTRVQGMARSEGYRYVTRIAEDSMRALRDGRVLNLERVDLPPAGASPRA
                     STSTEGKDS"
     aSDomain        complement(1866..2042)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MXAN_1528_PP-binding.1"
                     /evalue="1.70E-10"
                     /label="MXAN_1528_PP-binding.1"
                     /locus_tag="MXAN_1528"
                     /protein_end="1191"
                     /protein_start="1132"
                     /score="33.2"
                     /tool="antismash"
                     /translation="LIADVSHRPVSDVRPDALLSGDLGFDSLMLTELSSALEAAGVPLP
                     AVEDLTQVQTVEDL"
     aSModule        1866..5375
                     /complete
                     /domains="nrpspksdomains_MXAN_1528_NAD_binding_4.1"
                     /domains="nrpspksdomains_MXAN_1528_AMP-binding.1"
                     /domains="nrpspksdomains_MXAN_1528_PP-binding.1"
                     /locus_tags="MXAN_1528"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(2445..3734)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MXAN_1528_AMP-binding.1"
                     /evalue="1.30E-99"
                     /label="MXAN_1528_AMP-binding.1"
                     /locus_tag="MXAN_1528"
                     /protein_end="998"
                     /protein_start="568"
                     /score="325.4"
                     /tool="antismash"
                     /translation="ATVHAYRHRVAFRMVAGEKEERFTYGEVHRYAARVGSFLLAAGIK
                     HGDRVLLVSENRPEWGISYFGILRAGATVVPVDPGLSEAELVNIARRADARACLVSEDA
                     ARDFPGLFAALGDGVTVASLAEAMTGDPAHPDRIGPVRRSAAADDLASIIFTSGTTGTP
                     KGVMLTHRNFAALVAKLAGTFDIGVGDGVLSVLPLHHTFEFAAGFLTPFWRGAEITYID
                     ELTSDRLGEVFETGRITAMVGVPALWQLLHRKITQEFASRPPFIEQALKALMATHGELR
                     NRNNINLGKLLFWPVHRKFGGRIKVIVSGGSALPDDVHKAFHELGFNITEGYGLTEAAP
                     VLAVTKPGNKRQPGTVGRALPGIELRILNPDNDGLGEVLAKGPNVMPGYFGDREATEAV
                     LKDGWLHTGDLGRLDAEGHLYLVGRAKDVII"
     CDS_motif       complement(2541..2609)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_1528_0002"
                     /evalue="6.30E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="MXAN_1528"
                     /protein_end="966"
                     /protein_start="943"
                     /score="12.2"
                     /tool="antismash"
                     /translation="GEVLAKGPNVMPGYFGDREATEA"
     CDS_motif       complement(3225..3284)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_1528_0001"
                     /evalue="5.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="MXAN_1528"
                     /protein_end="738"
                     /protein_start="718"
                     /score="28.2"
                     /tool="antismash"
                     /translation="ASIIFTSGTTGTPKGVMLTH"
     aSDomain        complement(4368..5375)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MXAN_1528_NAD_binding_4.1"
                     /evalue="2.00E-49"
                     /label="MXAN_1528_NAD_binding_4.1"
                     /locus_tag="MXAN_1528"
                     /protein_end="357"
                     /protein_start="21"
                     /score="159.7"
                     /tool="antismash"
                     /translation="GATGFVGKVTLSMLLTRYGQDLDKVYVLVRKGSAASAERRFFDKV
                     ATSEPFQPLRDSLGDEGALAFIRQKVEVLDGDITDPWMGLEEPQVEALTGKVHAFINCA
                     GLVSFNPSLEVGLNVNTHGLKFAAALAVRWSVPLIHMSTAFVAGNRSGLVFEDEEVRGY
                     FPKREEMDGRDFSLEQELQDAARIVARLREQAEDRALTSTFRKKALDRLEEEGRDPNDE
                     KTLRLAVGRERKLWLSGELVRAGMERAAHWGWPNTYTYTKSLGEQVLAATPGLRYSIVR
                     PSIVESARHFPFPGWNEGFTTSAPLAFAGIKGPGGIPAGENTILDIIPVDQVAGA"
     gene            complement(5447..7057)
                     /locus_tag="MXAN_1529"
     CDS             complement(5447..7057)
                     /codon_start=1
                     /locus_tag="MXAN_1529"
                     /note="identified by Glimmer2; putative"
                     /product="hypothetical protein"
                     /protein_id="ABF93100.1"
                     /transl_table=11
                     /translation="MRPFKTLQKLYDEESQVVITEKGSPPRVLFHGENFLQEDLPVGTR
                     VIFPRPPLAGVPNVKAAIRYAINNPEGMEPLHALLKPGMRLTCVIDDISVPLPPMVTPD
                     VRQTILEIVLELAADSGVDDVHLIIANALHRRMTEGEMKRMVGEKIFDAYYPDRYYNHD
                     AEDPDGMVALERTSHGEEVSVNRRVAESDLIVYVNVNFVPMNGGHKSMGTGVSNYASLR
                     HHHNPKTIRASDSYMEPKTSALYKSNERIGRNIDKHLKVFHIETALNNRMFGGPTDFLA
                     KKEEDYTEADRLKFQAMRFALSKLPRAAARKVLNSVPAPYDVTGVYAGATEPTHAKTLE
                     TSYKQYVVPVEGQSDIVIFPIPFISPYSVNSILNPLLVQVMGLGYFYNLNRGVPLVKKG
                     GVLILLHPAYDEFDPEHHPSYIEFFHRLLPETRDSMKLEHKYEREFAENPSYVHLYRKG
                     NAYHGVHPFYMWYWGENGRQHVGKVIVAGAENNHVPALMGWDRTDTLTEAIEEARGFMG
                     RSATISLLRIAPTVMVDVK"
     gene            complement(7071..7736)
                     /locus_tag="MXAN_1530"
     CDS             complement(7071..7736)
                     /codon_start=1
                     /locus_tag="MXAN_1530"
                     /note="identified by match to protein family HMM PF00702;
                     match to protein family HMM TIGR01488; match to protein
                     family HMM TIGR01490"
                     /product="HAD-superfamily subfamily IB hydrolase,
                     TIGR01490"
                     /protein_id="ABF89683.1"
                     /transl_table=11
                     /translation="MSSKAAFFDVDGTLVKTNVVHVYAYYAMNRGSVLGIAGRTLSTAL
                     SVPLFGVMDAVDRKTFNEFFYRYYAGLSEDRLVTIAEDMFEDVLQPALFEQTQDLIDQA
                     RRSGCKIVLVTGALDFTMRPLARHLGADDMIANKMQFVGGKATGKVIPPIIEGANKANA
                     IRAYCTKEGLSLDKCHGYSDSASDYAMLAVVGRPTAVNPDLRLRSIARAYNWPILDLK"
     gene            complement(7827..8807)
                     /locus_tag="MXAN_1531"
     CDS             complement(7827..8807)
                     /NRPS_PKS="Domain: NAD_binding_4 (4-205). E-value: 5.8e-16.
                     Score: 50.2. Matches aSDomain:
                     nrpspksdomains_MXAN_1531_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     180.5; E-value: 8.6e-55)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="MXAN_1531"
                     /note="identified by similarity to GB:AAP18311.1; match to
                     protein family HMM PF00106; match to protein family HMM
                     PF01073; match to protein family HMM PF01370; match to
                     protein family HMM PF04321; match to protein family HMM
                     PF07993"
                     /product="conserved hypothetical protein"
                     /protein_id="ABF87343.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 5.3e-17, bitscore:
                     50.2, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 6.3e-13, bitscore:
                     36.8, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALITGAGGFLGMWLAKALAARGDSVTCLLRPGGDASGLAGLTY
                     TRVEGDVTVPSTLSAAVAGQDVVFHLAGARRGATRDDFMRVNAEGTRHLCEAMVAAGHR
                     PRLVLTGSLAACGPSTPTRPHVEEDAFHPHEWYGESKAEAERIAFSYGDRLPVTVSRPP
                     RILGPGDRENLPFFKMAQRGIRLELSGGPRPLTMVDVEDVVDILLLQATHPAAIGEAFF
                     CAGPGEPLSLEKVQDLGAQALGLTPRTVRVSPALLRAMATAADGVSQLTGRKLALSRKM
                     AKQLLAPAWTCSGAKAERLLGFHPQRDLADSIRRSVQWYREQGWL"
     aSDomain        complement(8193..8795)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MXAN_1531_NAD_binding_4.1"
                     /evalue="5.80E-16"
                     /label="MXAN_1531_NAD_binding_4.1"
                     /locus_tag="MXAN_1531"
                     /protein_end="205"
                     /protein_start="4"
                     /score="50.2"
                     /tool="antismash"
                     /translation="ITGAGGFLGMWLAKALAARGDSVTCLLRPGGDASGLAGLTYTRVE
                     GDVTVPSTLSAAVAGQDVVFHLAGARRGATRDDFMRVNAEGTRHLCEAMVAAGHRPRLV
                     LTGSLAACGPSTPTRPHVEEDAFHPHEWYGESKAEAERIAFSYGDRLPVTVSRPPRILG
                     PGDRENLPFFKMAQRGIRLELSGGPRPLTMVDVEDVVD"
     CDS_motif       complement(8475..8588)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_1531_0002"
                     /evalue="1.50E-01"
                     /label="PKSI-KR_m1"
                     /locus_tag="MXAN_1531"
                     /protein_end="111"
                     /protein_start="73"
                     /score="4.8"
                     /tool="antismash"
                     /translation="ARRGATRDDFMRVNAEGTRHLCEAMVAAGHRPRLVLTG"
     CDS_motif       complement(8736..8798)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_1531_0001"
                     /evalue="2.30E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="MXAN_1531"
                     /protein_end="24"
                     /protein_start="3"
                     /score="7.5"
                     /tool="antismash"
                     /translation="LITGAGGFLGMWLAKALAARG"
ORIGIN
        1 tcaggtgttc tcgcgcagct ccgccagccg gcccttggtg ccaggcaggc tctggggcgg
       61 catcttcccg tagatgtgct gcaccgtctc ggagagcgtc tcctggatgt cgcgcgcgcg
      121 gaagccgagc tcggcctccg ccttggatgc gtccagccag aaccagtgct cgccgatgtc
      181 gatttcctgc gggtccagcg tcggcgtggt gccgcgcacc ttggcccagc gctccagcag
      241 cttcccgccg agcacgttga ccttggaggg gagcttcagc ttcggcgcgg gcacgcccga
      301 caggcgctcc agccgctgga agaagtcctt catggacaga ttcaccccca tgaggtgacg
      361 gccgtacacc tcgccccggg tgagcgcctg gacgaaggcg tccgccgcgt cgcgcgcgtc
      421 cacgaaggag atgccgccgc ccggcatggc cggaatctcg cggttgagga acttcaccac
      481 cgtccatgtg gaggacagcc ggtcatcccc gggccccatc agcaggctgg ggttgagcac
      541 caccagggga atctcgtgct tgcggcagta tgcgagcgcc agcttctcct cgtagatttt
      601 cgacaggtag tagggccact ggcccaccac cgtaatcggg tagtcggcgc tctcgtcgcg
      661 gacgtgcgcc tccttcgaca ccgcgatggt gccggaggtg gaggccagca ccacgcgctt
      721 cacgccggcc tcgcgcacgt cccgcagcag ctcgcgcgtg ctgtccacgt gcagctcgaa
      781 catcttccgc gcgtccttcg gctggaagga gacgagcccc gccaggtggt agacggcgtc
      841 cacgccctcc agcgcgcggc gcaccgcgtc ccggttcttc aagtcaccgg ggacgtactc
      901 cgtgcccgcg tagggggcgc ccgaaggccg cgagcggccg atgagccgca cctcgtggcc
      961 cgccgccacc agcctgggca ccaggtgcgt gcccagaaag cccgtgcctc ccgtcaccag
     1021 cagcttcacg agtccttccc ttccgtggac gtggacgcgc ggggactggc cccggccgga
     1081 ggcaggtcca cgcgctccag gttcagcacc cggccgtcgc gcagcgcccg catggagtcc
     1141 tcggcgatgc gcgtgacgta gcggtatccc tccgagcgcg ccatgccctg cacccgcgtg
     1201 cgcaggtccg cgtggcccag cgccggaccg atgttcaccc gcaggggcgt cttcgtcttg
     1261 ggcagcacgc tgcccttggg cagcgcgtcg aaggcgccgc cgatgtacag cggcagcacg
     1321 tccatgttga aggtgagcgc caggtagccc agcgtggact tgaactccat cagctcaccg
     1381 gtggtggagc gcgtgccctc cgggaagatg aggacgttga agccctgacg cagcgcctcg
     1441 cccgccatcc gcagcgactc gcgcagcgag ccctgccgtt caatggggat caggttggtg
     1501 aagttctcga accaggcgcg cttgagcggc gtgttgaaga agtagtcgcg cgccgccagg
     1561 gacaccagtc gctcgccctg gtcacccagc gccacgcgga ccaggcccgc gtccaggtgg
     1621 ctggagtggt tggcgatgac gaggaagttg cggttctgcg ggatgaagga cttgcccgtc
     1681 accttcacgt cgaacacgcc gccgtagagc accttctgcc cgaaggacaa gagctgacgg
     1741 cccacgtccg ccaccacgtc gggcaccgga atctccacct cttccgcgcg ctcgttctcc
     1801 ttggagatct ccttcgcgcg cgtctccacc gtggggcgct tgccggagga cgccaccacc
     1861 ttgcgcaggt cctccactgt ctgcacctgc gtcaggtcct ccactgcggg cagcggcacg
     1921 ccggcggcct ccagcgcgga ggacagctcg gtgagcatca gcgagtcgaa gccgaggtcc
     1981 ccgctgagca gcgcgtccgg acgcacgtcg gacaccggcc ggtggctgac gtccgcgatg
     2041 agcgggaaga gccagtccgc gatgccaccc gtggtggggt tggccgcctt ctcgcgcgcc
     2101 ttgctggcgc tggccgccat gcgctcctgg cgcttgagct cctccaccac ctgcttgcgc
     2161 ttcacgctgc gcttggcggt gcggggcagc tcgccgtccc acaggcgcag caccttcacg
     2221 cgccggtaga agggcatgcc cgcgctcacc ttgcggaagt gctcctccaa ctcgcggcgc
     2281 acttcctcgc gtgggcggtc cgcgtagtcg ggcacgcaca ggcacgccac cttctcaccg
     2341 cccgcgtcgt cgggcaggcc gacgatggac agctccttga tgtgcgtgtg gtcctggtac
     2401 agctcctcca actcgtccgg gtagatgttc ttcccgttgt ggtcgatgat gacgtccttc
     2461 gcgcggccca ccaggtacag gtggccctcc gcgtccagac gtcccaggtc gcccgtgtgg
     2521 agccagccgt ccttgagcac cgcctcggtg gcctcgcggt cgccgaagta gccgggcatg
     2581 acgttggggc ccttggccag cacttcaccc aacccgtcgt tgtccggatt gaggatgcgc
     2641 agctcgatgc cgggcagcgc gcggcccacc gtaccgggct ggcgcttgtt gccgggcttc
     2701 gtcaccgcca gcaccggcgc ggcctccgtc aggccgtagc cctccgtgat gttgaagccc
     2761 agctcgtgga aggccttgtg cacgtcgtcc ggcagcgccg agccgcccga cacgatgacc
     2821 ttgatacgcc cgccgaactt gcggtgcacc ggccagaaca gcagcttgcc caggttgatg
     2881 ttgttgcggt tgcgcagctc gccgtgggtg gccatcagcg ccttgagcgc ctgttcgatg
     2941 aacggcgggc ggctggcgaa ctcctgcgta atcttgcgat gcaagagctg ccacagcgcc
     3001 ggcacgccca ccatggcggt gatgcggccc gtctcgaaca cctcgcccag ccggtccgac
     3061 gtcagctcgt cgatgtaggt gatttccgcc ccgcgccaga acggggtgag gaagccggcg
     3121 gcgaactcga aggtgtggtg cagcggcagg acggacagca cgccgtcgcc cacgccgatg
     3181 tcgaaggtcc ccgccagctt cgccaccagc gcggcgaagt tccggtgggt gagcatgacg
     3241 cccttgggcg tgcccgtggt gccggaggtg aagatgatgc tggccaggtc atccgccgcg
     3301 gcggacctgc gcactggccc gatgcggtcc gggtgcgccg ggtcgcctgt catcgcctcc
     3361 gcgaggctgg ccacggtgac gccgtcaccc agcgcggcga agaggccggg gaagtcccgg
     3421 gccgcgtcct cggagacgag gcacgcgcgc gcgtccgccc ggcgggcgat gttgacgagc
     3481 tccgcctcgc tcaagcccgg gtccaccgga acgacggtgg cgcccgcgcg caggatgccg
     3541 aagtagctga tgccccactc gggccggttc tccgacacca gcagcacgcg gtcgccgtgc
     3601 ttgatgcccg cggccagcag gaagctgccc acgcgcgcgg catagcggtg cacctcgccg
     3661 taggtgaagc gctcctcctt ctcgcccgcc accatgcgga aggccacgcg gtgccggtac
     3721 gcatgcaccg tggcttccat caactccagc aggtcgcggt gcgcggggat gacggtgcgc
     3781 ttctcgcgct ccgactccat gcccgggaac acccacttct ccaggccagg gaggtgtgtc
     3841 cccaggaagt actcgcgcca gtcgatgtgc tccgggtccc agggcacctt cagccggtcc
     3901 gcgtgcgcca tgcgcgcata cacggagcgg gtgttgtcgc agcggaagac gtagcggttc
     3961 tcgtagagga aggggaggaa cagctccgtc agggcgatga tgccctgggc gttgtcgtcc
     4021 acctcgtcca gcgacacctt cgccttgtcc agcatggcct ggacggccgg ggcgccccac
     4081 gcgggacgca cctcgtcgat ggccttcttc aggaagcgcg cgccgcgcga cagcatgggc
     4141 gcgctgaaca gctcgaactc cttcttgctg accggctgcg gctcgacgcg cgagcgcagc
     4201 ttgttcatca gcgcgttgcc ggactcgcgg ttgcggtagt agcgccgccg gtacaggccc
     4261 accagctcca cggagcggcc ggcgtagaag ggattcatat cgccggaggc gagctggtag
     4321 atgcgccgct cctccacgtc catggcatgc gcggtgatgc cgatggtggc gcccgccacc
     4381 tggtccaccg ggatgatgtc caggatggtg ttctcgcccg cggggatgcc gccggggccc
     4441 ttgatgcccg cgaaggccag gggcgcggag gtggtgaagc cctcgttcca gccggggaag
     4501 gggaagtgcc gcgcgctctc cacgatggag ggccggacga tggagtagcg caggcccggc
     4561 gtggccgcga gcacctgctc gcccagggac ttggtgtacg tgtacgtgtt gggccagccc
     4621 cagtgggcgg cgcgctccat gccggcgcgc accagctcgc cgctgagcca cagcttgcgc
     4681 tcacggccca ccgccagccg cagcgtcttc tcgtcgttgg ggtcgcggcc ttcttcctcc
     4741 agccggtcca acgccttctt gcggaaggtg gacgtgaggg cccggtcctc ggcctgctcg
     4801 cgcagccgcg cgacgatgcg cgccgcgtcc tgcagttcct gctccaggct gaagtcgcgg
     4861 ccgtccatct cctcccgctt ggggaagtag ccgcgaacct cctcgtcctc gaagacgagc
     4921 ccgctgcggt tgccggccac gaaggccgtg gacatgtgaa tcagcgggac ggaccagcgc
     4981 accgccagcg ccgcggcgaa cttcaggccg tgggtgttga cgttgaggcc cacctccagc
     5041 gacgggttga aggacaccag accggcgcag ttgatgaacg cgtgcacctt gccggtgagc
     5101 gcctccacct ggggctcttc caggcccatc cacgggtcgg tgatgtcgcc gtccagcacc
     5161 tccaccttct ggcggatgaa ggccagcgcg ccttcatccc ccaggctgtc tcgcagcggc
     5221 tggaagggct cactggtggc gaccttgtcg aagaagcggc gctcggcgga cgcggcgctg
     5281 cccttgcgga ccagcacgta caccttgtcc aggtcctgcc cgtagcgggt cagcagcatg
     5341 gacagcgtca ccttgcccac gaagccggtg gcgcccgcga agagcaggcg cttgccggtg
     5401 aaggtctggg tgacgttcag ctcgggaagg gcggccatgg gcgtcctcac ttcacatcca
     5461 ccatcaccgt gggcgcgatg cgcagcaggc tgatggtggc cgagcggccc atgaacccgc
     5521 gagcctcttc aatggcctcg gtgagcgtgt cggtgcggtc ccagcccatc agggcgggga
     5581 catggttgtt ctccgcgccc gcgacaatga ccttgcctac gtgctggcgg ccattctcgc
     5641 cccagtacca catgtagaag gggtgcacgc cgtggtaggc gttgcccttg cggtacaggt
     5701 gcacgtagct ggggttctcc gcgaactcgc gctcgtactt gtgctccagc ttcatggagt
     5761 cgcgcgtctc cggcagcagc cggtggaaga actcgatgta gctggggtgg tgctccgggt
     5821 cgaactcgtc gtaggccggg tgcagcagga tgagcacgcc gcccttcttc accagcggca
     5881 caccgcggtt caggttgtag aagtagccca gccccatcac ctgcaccagc agcgggttga
     5941 ggatggagtt gacgctgtac ggggagatga acgggatggg gaagatgacg atgtcgctct
     6001 gtccctccac cggcaccacg tactgcttgt agctcgtctc cagcgtcttc gcgtgcgtgg
     6061 gctccgtggc tccggcgtag acgcccgtga cgtcgtaggg cgcggggacg gagttgagca
     6121 ccttgcgcgc cgccgcgcgc ggcagcttgg acagcgcgaa gcgcatggcc tggaacttca
     6181 gccggtccgc ctccgtgtag tcctcttcct tcttcgccag gaagtcggtg gggccgccga
     6241 acatgcggtt gttcagcgcc gtctcgatgt ggaagacctt caggtgcttg tcgatgttgc
     6301 gcccgatgcg ctcgttgctc ttgtagagcg cgctcgtctt cggctccata tagctgtcgg
     6361 aggcgcggat ggtcttcggg ttgtggtggt gccgcagcga cgcgtagttg gacacgccgg
     6421 tgcccatgga cttgtgcccg ccgttcatgg gcacgaagtt cacgttcacg tagacgatga
     6481 ggtcgctctc cgccacgcgg cggttcaccg acacctcttc accgtgggac gtgcgctcca
     6541 gcgcgaccat cccgtccggg tcctcggcgt cgtggttgta gtagcggtcc gggtagtagg
     6601 cgtcgaagat cttctcgccc accatgcgct tcatctcgcc ttccgtcatc cggcggtgca
     6661 gggcgttggc gatgatgagg tgcacgtcgt ccacgccgct gtcggcggcc agctccagga
     6721 cgatttccag gatggtctgc cgcacgtccg gcgtgaccat gggcggcagc ggcacgctga
     6781 tgtcgtcgat gacgcacgtc aggcgcatgc ccggcttgag gagcgcgtgc agcggctcca
     6841 tgccctccgg gttgttgatg gcgtagcgga tggcggcctt gacgttgggc acgccggcca
     6901 ggggcgggcg cgggaagatg acgcgcgtgc cgaccggaag gtcttcctgc aggaagttct
     6961 caccgtggaa cagcacgcgc ggggggctgc ccttctcggt gatgacgacc tggctttcct
     7021 cgtcgtacag cttctggagc gtcttgaacg ggcgcatggc gtgggggctc ttacttgagg
     7081 tcgaggatgg gccagttgta ggcgcgcgcg atggagcgca gccgcaggtc cgggttcacc
     7141 gcggtgggac ggcccaccac cgcgagcatc gcgtagtcag aggcgctgtc ggagtagccg
     7201 tggcacttgt ccagcgacag gccttccttg gtgcagtagg cgcggatggc gttcgccttg
     7261 ttcgcgcctt cgatgatggg cggaatcacc ttgccggtcg ccttgccgcc cacgaactgc
     7321 atcttgttgg cgatcatgtc gtcggcgccc aggtggcgcg ccagcgggcg catggtgaag
     7381 tccagcgcgc ccgtgacgag gacaatcttg cagccgctgc ggcgagcctg gtcgatgagg
     7441 tcctgcgtct gctcgaagag ggcgggctgc agcacgtcct cgaacatgtc ctcggcgatg
     7501 gtgaccaggc ggtcttcgct caggcccgcg tagtagcggt agaagaactc gttgaacgtc
     7561 ttgcggtcca ccgcgtccat gacaccgaag agcggcacgc tgagggcggt gctcagggtc
     7621 cgccccgcga tgcccaggac ggagccgcgg ttcatcgcgt agtacgcgta gacgtggacg
     7681 acgttcgtct tcacgagcgt cccgtcgaca tcgaagaagg cagctttcga ggacatgggg
     7741 ctgcgggctt cctgacactt cgaggggggg gaggtcaatg atgccgggag tttggcgtgc
     7801 ctcccggcgg ctcgggggag aaggggctac agccagccct gctcccggta ccactgcacg
     7861 ctgcgacgga tggagtccgc caggtcgcgc tgggggtgaa agccgagcag ccgctcggcc
     7921 ttggccccgg agcacgtcca ggcaggcgcc aacagttgct tcgccatctt ccggctcagg
     7981 gccagcttgc ggcccgtcag ttgggacacg ccgtccgccg ccgtggccat ggcccgcagt
     8041 agcgcggggg acacgcgcac ggtgcggggc gtcagtccca gggcctgcgc gcccaggtcc
     8101 tgcaccttct ccaaggagag gggctcgccg gggcccgcgc agaagaaggc ctcaccgatg
     8161 gccgccgggt gggtggcctg caacaagagg atgtccacca cgtcctccac atccaccatg
     8221 gtcaacgggc gagggccgcc ggacagctcc agccggatgc cgcgctgagc catcttgaag
     8281 aagggaaggt tctccctgtc cccgggcccc aggatgcgcg gcggccggga caccgtgacg
     8341 ggcagccggt ctccatagga gaaggcgatg cgctccgcct ccgccttgct ctccccatac
     8401 cattcgtggg gatggaaggc gtcttcctcc acatgcggcc gggtgggcgt ggacggaccg
     8461 caggcggcca gcgagcccgt gagcaccagc cgggggcggt ggcccgcggc caccatggcc
     8521 tcgcacaggt ggcgggtgcc ctccgcgttg acgcgcatga agtcgtcgcg tgtcgcgccg
     8581 cggcgagcgc ccgccaggtg gaagacgacg tcctggcccg ccaccgcggc cgagagcgtg
     8641 gagggcaccg tcacgtcgcc ctccacccgc gtgtaggtca accccgcgag ccccgaggca
     8701 tctcctcccg ggcgcaacag gcatgtgacg ctgtctcccc gcgcggccag ggccttggcc
     8761 aaccacattc ccaggaagcc gcctgcaccg gtgatgaggg ctctcat
//
