BGC0000874: blasticidin S biosynthetic gene cluster from Streptomyces griseochromogenes
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Location: 1 - 36,677 nt. (total: 36,677 nt).
This entry is originally from NCBI GenBank AY196214.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000874
Short description blasticidin S biosynthetic gene cluster from Streptomyces griseochromogenes
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
AY196214.1
via
Compounds
  • blasticidin S
Species Streptomyces griseochromogenes [taxonomy]
References
Chemical products information
blasticidin S Evidence:
Copy SMILES
C17H26N8O5
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAP03101.1
  • bls_orf9
 1 - 823 (-) putative ATP-binding protein
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    • AAP03102.1
    • bls_orf8
    		 1149 - 2327 (+) putative 2-component system sensor kinase
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      • AAP03103.1
      • bls_orf7
      		 2324 - 2992 (+) putative 2-component system response regulator
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        • AAP03104.1
        • bls_orf6
        		 4658 - 6226 (-) putative secreted peptidase
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          • AAP03105.1
          • bls_orf5
          		 6609 - 7595 (+) possible hydrolase
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            • AAP03106.1
            • bls_orf4
            		 8856 - 9323 (+) putative oxidoreductase
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              • AAP03107.1
              • bls_orf3
              		 9371 - 10105 (-) putative transcriptional regulator
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                • AAP03108.1
                • bls_orf2
                		 10344 - 11375 (+) hypothetical protein, pqqE family
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                  • AAP03109.1
                  • bls_orf1
                  		 11432 - 14161 (+) putative serine/threonine protein kinase
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                    • AAP03110.1
                    • blsS
                    		 14413 - 16245 (-) putative GMC oxidoreductase
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                      • AAP03111.1
                      • blsR
                      		 16242 - 17681 (-) hypothetical protein BlsR
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                        • AAP03112.1
                        • blsQ
                        		 17678 - 18397 (-) putative transcriptional regulator
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                          • AAP03113.1
                          		 18552 - 19031 (-) putative membrane protein
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                            • AAP03114.1
                            • blsO
                            		 19165 - 19635 (-) putative membrane protein
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                              • AAP03115.1
                              • blsA
                              		 19872 - 20612 (+) possible methyltransferase
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                                • AAP03116.1
                                • blsB
                                		 20804 - 22345 (+) putative carboxyesterase
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                                  • AAP03117.1
                                  • blsC
                                  		 22394 - 22819 (+) putative regulatory protein
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                                    • AAP03118.1
                                    • blsD
                                    		 23999 - 24985 (+) cytosylglucuronic acid synthase
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                                      • AAP03119.1
                                      • blsE
                                      		 25034 - 26068 (+) hypothetical protein
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                                        • AAP03120.1
                                        • blsF
                                        		 26117 - 27070 (+) hypothetical protein
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                                          • AAP03121.1
                                          • blsG
                                          		 27190 - 28422 (+) arginine aminomutase
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                                            • AAP03122.1
                                            • blsH
                                            		 28419 - 29597 (+) putative cytosinine synthase
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                                              • AAP03123.1
                                              • blsI
                                              		 29594 - 30790 (+) putative ligase
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                                                • AAP03124.1
                                                • blsJ
                                                		 30848 - 32092 (+) putative efflux protein
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                                                  • AAP03125.1
                                                  • blsK
                                                  		 32325 - 34064 (+) hypothetical protein BlsK
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                                                    • AAP03126.1
                                                    • blsL
                                                    		 34103 - 34744 (+) putative leucyldemethylblasticidin S guanidino methyltransferase
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                                                      • AAP03127.1
                                                      • blsM
                                                      		 34826 - 35278 (+) putative (deoxy)cytidine deoxyribosyltransferase
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                                                        • AAP03128.1
                                                        • blsN
                                                        		 35450 - 36223 (+) conserved hypothetical protein
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                                                          Biosynthesis information
                                                          Annotation changelog

                                                          Entry version: 4

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2022-10-07
                                                          Update chemical activity to schema version 2.11
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 3

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2022-09-15
                                                          Updated bioactivity data
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 2

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2019-10-16
                                                          Migrated from v1.4
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          2019-10-16
                                                          Updated compound(s) information (NPAtlas curation)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 1

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2015-06-12
                                                          Submitted
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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