BGC0000876 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000876 (Streptomyces tendae)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like	1	9,389	neopolyoxin C	other:other	100%

BGC0000876 - Region 1 - NRPS-like

Download region GenBank file

Download region SVG

Location: 1 - 9,389 nt. (total: 9,389 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 9,390
Label		BGC0000876

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000876	1.00	Other	neopolyoxin C	Streptomyces tendae
BGC0001206	0.32	Other	indolmycin	Streptomyces griseus subsp. griseus
BGC0002031	0.32	Alkaloid	kitasetaline	Kitasatospora setae KM-6054
BGC0000016	0.29	Other	amphotericin B	Streptomyces nodosus
BGC0000900	0.28	Other	ferrichrome	Aspergillus oryzae
BGC0000979	0.27	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980	0.27	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0000348	0.26	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001561	0.25	NRP	curacomycin	Streptomyces curacoi
BGC0002157	0.24	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000876	1.00	Other	neopolyoxin C	Streptomyces tendae
BGC0001206	0.66	Other	indolmycin	Streptomyces griseus subsp. griseus
BGC0002031	0.65	Alkaloid	kitasetaline	Kitasatospora setae KM-6054
BGC0000016	0.63	Other	amphotericin B	Streptomyces nodosus
BGC0000900	0.62	Other	ferrichrome	Aspergillus oryzae
BGC0000979	0.60	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980	0.60	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0000348	0.60	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001561	0.59	NRP	curacomycin	Streptomyces curacoi
BGC0002157	0.57	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 9389:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

nikP1

AMP-binding (77..488): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAESIAVITK
Nearest Stachelhaus code(s):: Arg DAEDIGAITK (59% 8Å match)
Stachelhaus code match:: 70% (weak)