BGC0000877: polyoxin A biosynthetic gene cluster from Streptomyces cacaoi subsp. asoensis
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Location: 1 - 46,066 nt. (total: 46,066 nt).
This entry is originally from NCBI GenBank EU158805.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
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KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000877
Short description polyoxin A biosynthetic gene cluster from Streptomyces cacaoi subsp. asoensis
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Other
Loci NCBI GenBank: EU158805.1
Compounds
  • polyoxin A
  • polyoxin H
Species Streptomyces cacaoi subsp. asoensis [taxonomy]
References
Chemical products information
polyoxin A
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C23H32N6O14
Chemical database entries
PubCHEM
polyoxin H
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C22H30N6O13
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABX24473.1
 437 - 1213 (+) hypothetical protein
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  • ABX24474.1
 1356 - 2039 (+) putative peptidase
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  • ABX24475.1
 2198 - 3778 (+) hypothetical protein
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  • ABX24476.1
 3775 - 4758 (+) aspartate aminotransferase
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  • ABX24477.1
 4761 - 5282 (-) putative acetyltransferase
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  • ABX24478.1
 5375 - 5905 (+) putative GCN5-related N-acetyltransferase
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  • ABX24479.1
 5877 - 7241 (-) putative flavin-containing monooxygenase
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  • ABX24480.1
 7427 - 8080 (+) transcriptional regulatory protein
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  • ABX24481.1
 8077 - 9789 (+) putative cholesterol oxidase
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  • ABX24482.1
 9786 - 10397 (+) hypothetical protein
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  • ABX24483.1
 10719 - 11654 (+) hypothetical protein
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  • ABX24484.1
  • polB
 11999 - 12772 (+) thymidylate synthase
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  • ABX24485.1
  • polA
 12838 - 14175 (+) uridine-5'-monophosphate enolpyruvyltransferase
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  • ABX24486.1
  • polQ2
 14230 - 14796 (-) putative adenylate kinase
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  • ABX24487.1
  • polQ1
 14793 - 16052 (-) putative membrane protein
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  • ABX24488.1
  • polP
 16218 - 17060 (-) acetylglutamate kinase
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  • ABX24489.1
  • polO
 17057 - 18778 (-) carbamoyltransferase
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  • ABX24490.1
  • polN
 18775 - 19281 (-) amino-acid N-acetyltransferase
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  • ABX24491.1
  • polM
 19274 - 20041 (-) short-chain dehydrogenase
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  • ABX24492.1
  • polL
 20099 - 20830 (-) hypothetical protein
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  • ABX24493.1
  • polK
 20887 - 21528 (-) putative hydroxylase
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  • ABX24494.1
  • polJ
 21515 - 22336 (-) putative phosphatase
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  • ABX24495.1
  • polI
 22333 - 23475 (-) putative aminotransferase
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  • ABX24496.1
  • polH
 23472 - 24881 (-) putative radical SAM protein
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  • ABX24497.1
  • polG
 24874 - 26166 (-) putative carboxylase
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  • ABX24498.1
  • polF
 26196 - 27023 (-) putative molybdopterin oxidoreductase
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  • ABX24499.1
  • polE
 27075 - 28187 (-) hypothetical protein
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  • ABX24500.1
  • polD
 28210 - 28857 (-) putative hydroxylase
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  • ABX24501.1
  • polC
 28862 - 29476 (-) putative hydroxylase
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  • ABX24502.1
  • polY
 29681 - 32569 (-) response regulator
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  • ABX24503.1
  • polR
 32787 - 36122 (+) pathway-specific regulatory protein
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  • ABX24504.1
 36264 - 37124 (+) putative cyclase family protein
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  • ABX24505.1
 37321 - 38124 (-) putative transport protein
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  • ABX24506.1
 38323 - 41112 (+) ATPase E1-E2 type
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  • ABX24507.1
 41109 - 41768 (+) TrkA-N domain protein
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  • ABX24508.1
 41765 - 42421 (+) putative potassium uptake protein
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  • ABX24509.1
 42509 - 43648 (-) cation-transporting ATPase
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  • ABX24510.1
 43737 - 44252 (+) hypothetical protein
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  • ABX24511.1
 44523 - 46016 (-) respiratory-chain NADH dehydrogenase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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