BGC0000877: polyoxin A biosynthetic gene cluster from Streptomyces cacaoi subsp. asoensis
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Location: 1 - 46,066 nt. (total: 46,066 nt).
This entry is originally from NCBI GenBank EU158805.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000877
Short description polyoxin A biosynthetic gene cluster from Streptomyces cacaoi subsp. asoensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
EU158805.1
via
Compounds
  • polyoxin A
  • polyoxin H
Species Streptomyces cacaoi subsp. asoensis [taxonomy]
References
Chemical products information
polyoxin A Evidence:
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C23H32N6O14
Chemical database entries
PubCHEM
polyoxin H Evidence:
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C22H30N6O13
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABX24473.1
 437 - 1213 (+) hypothetical protein
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    • ABX24474.1
    		 1356 - 2039 (+) putative peptidase
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      • ABX24475.1
      		 2198 - 3778 (+) hypothetical protein
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        • ABX24476.1
        		 3775 - 4758 (+) aspartate aminotransferase
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          • ABX24477.1
          		 4761 - 5282 (-) putative acetyltransferase
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            • ABX24478.1
            		 5375 - 5905 (+) putative GCN5-related N-acetyltransferase
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              • ABX24479.1
              		 5877 - 7241 (-) putative flavin-containing monooxygenase
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                • ABX24480.1
                		 7427 - 8080 (+) transcriptional regulatory protein
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                  • ABX24481.1
                  		 8077 - 9789 (+) putative cholesterol oxidase
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                    • ABX24482.1
                    		 9786 - 10397 (+) hypothetical protein
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                      • ABX24483.1
                      		 10719 - 11654 (+) hypothetical protein
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                        • ABX24484.1
                        • polB
                        		 11999 - 12772 (+) thymidylate synthase
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                          • ABX24485.1
                          • polA
                          		 12838 - 14175 (+) uridine-5'-monophosphate enolpyruvyltransferase
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                            • ABX24486.1
                            • polQ2
                            		 14230 - 14796 (-) putative adenylate kinase
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                              • ABX24487.1
                              • polQ1
                              		 14793 - 16052 (-) putative membrane protein
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                                • ABX24488.1
                                • polP
                                		 16218 - 17060 (-) acetylglutamate kinase
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                                  • ABX24489.1
                                  • polO
                                  		 17057 - 18778 (-) carbamoyltransferase
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                                    • ABX24490.1
                                    • polN
                                    		 18775 - 19281 (-) amino-acid N-acetyltransferase
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                                      • ABX24491.1
                                      • polM
                                      		 19274 - 20041 (-) short-chain dehydrogenase
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                                        • ABX24492.1
                                        • polL
                                        		 20099 - 20830 (-) hypothetical protein
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                                          • ABX24493.1
                                          • polK
                                          		 20887 - 21528 (-) putative hydroxylase
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                                            • ABX24494.1
                                            • polJ
                                            		 21515 - 22336 (-) putative phosphatase
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                                              • ABX24495.1
                                              • polI
                                              		 22333 - 23475 (-) putative aminotransferase
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                                                • ABX24496.1
                                                • polH
                                                		 23472 - 24881 (-) putative radical SAM protein
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                                                  • ABX24497.1
                                                  • polG
                                                  		 24874 - 26166 (-) putative carboxylase
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                                                    • ABX24498.1
                                                    • polF
                                                    		 26196 - 27023 (-) putative molybdopterin oxidoreductase
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                                                      • ABX24499.1
                                                      • polE
                                                      		 27075 - 28187 (-) hypothetical protein
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                                                        • ABX24500.1
                                                        • polD
                                                        		 28210 - 28857 (-) putative hydroxylase
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                                                          • ABX24501.1
                                                          • polC
                                                          		 28862 - 29476 (-) putative hydroxylase
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                                                            • ABX24502.1
                                                            • polY
                                                            		 29681 - 32569 (-) response regulator
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                                                              • ABX24503.1
                                                              • polR
                                                              		 32787 - 36122 (+) pathway-specific regulatory protein
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                                                                • ABX24504.1
                                                                		 36264 - 37124 (+) putative cyclase family protein
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                                                                  • ABX24505.1
                                                                  		 37321 - 38124 (-) putative transport protein
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                                                                    • ABX24506.1
                                                                    		 38323 - 41112 (+) ATPase E1-E2 type
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                                                                      • ABX24507.1
                                                                      		 41109 - 41768 (+) TrkA-N domain protein
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                                                                        • ABX24508.1
                                                                        		 41765 - 42421 (+) putative potassium uptake protein
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                                                                          • ABX24509.1
                                                                          		 42509 - 43648 (-) cation-transporting ATPase
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                                                                            • ABX24510.1
                                                                            		 43737 - 44252 (+) hypothetical protein
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                                                                              • ABX24511.1
                                                                              		 44523 - 46016 (-) respiratory-chain NADH dehydrogenase
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                                                                                Biosynthesis information
                                                                                Annotation changelog

                                                                                Entry version: 4

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2022-10-07
                                                                                Update chemical activity to schema version 2.11
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                Entry version: 3

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2022-09-15
                                                                                Updated bioactivity data
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                Entry version: 2

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2019-10-16
                                                                                Migrated from v1.4
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                2019-10-16
                                                                                Updated compound(s) information (NPAtlas curation)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                Entry version: 1

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2015-06-12
                                                                                Submitted
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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