LOCUS       BGC0000878              9120 bp    DNA     linear   BCT 14-JUL-2016
DEFINITION  Streptomyces alboniger napH, pur7, pur10, pur6, pur4, pur5 and pur3
            genes.
ACCESSION   BGC0000878
VERSION     BGC0000878
KEYWORDS    .
SOURCE      Streptomyces alboniger
  ORGANISM  Streptomyces alboniger
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces; Streptomyces aurantiacus group.
COMMENT     Related sequence M25346.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 20:55:35
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9120
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            <1..435
                     /gene="orfA"
     CDS             <1..435
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q53736"
                     /gene="orfA"
                     /protein_id="CAA63157.1"
                     /transl_table=11
                     /translation="IDELRSCGIWQPRNGVASEWEHYVGRLADSFGLSLAFSGAALSDE
                     HFLEHLWSHGEMACLAGADVSYAFSPDIRSIPLVDPTPVYPWSMVWRRQAGHPLVDRLV
                     GLAKRSAGDWLTHVPGEIWLPAPDRALLRGAGVDVDAVRG"
     source          1..9120
                     /culture_collection="ATCC:12461"
                     /db_xref="taxon:132473"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces alboniger"
                     /strain="ATCC 12461"
                     /type_material="type strain of Streptomyces alboniger"
     subregion       1..9120
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="Other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..9120
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     sig_peptide     720..818
                     /gene="napH"
     gene            720..2177
                     /gene="napH"
     CDS             720..2177
                     /codon_start=1
                     /db_xref="GOA:Q53737"
                     /db_xref="HSSP:1CP7"
                     /db_xref="InterPro:IPR003137"
                     /db_xref="InterPro:IPR007484"
                     /db_xref="UniProtKB/TrEMBL:Q53737"
                     /gene="napH"
                     /product="N-acetylpuromycin N-acetylhydrolase"
                     /protein_id="CAA63158.1"
                     /transl_table=11
                     /translation="MLHRIQRKRAMTAGAVGVLFLAQLVISSSSAAAGESEVTPPPLSQ
                     DRIEKHLTRFERIADAHGGDRASGTQGYAESVDYTEKLLKKAGYSTQRQQFPFRYTRTL
                     EEKLVLRDGSTPGVVVSGYSQSTPRGGLTARPTAVGGDTERRQGCRAGAYDGVPAGGRI
                     ALVDAGGCSMDDKQRVAADAGAAAVIVANTGPGELHTWLADPEAARIPIGGVTQETGRL
                     LAAEARAGRTVQLTLRSLTERRTTENLIAVSPRGNPEHTVVSGAHLDSVPEGPGINDNG
                     VAAAVLLESALAAAKDHGTRAEDNRLVFGFWGAEEFGLLGSQHYVDSLTQEERERTGLY
                     LNLEMIGSPNYGLFTLDSKATDPVTGQRPAPGSDEIERELTDAFAAQGRTSLPGPADGR
                     SDYVAFLGAGIPTGGLYGGSFEAKTPEQAALWGGTAGRPYDPCYHLTCDRTAQYSREAA
                     TLHGQAFQTVLTHYSRHRLGEAAAHHG"
     gene            2170..2628
                     /gene="pur7"
     CDS             2170..2628
                     /codon_start=1
                     /db_xref="GOA:Q53738"
                     /db_xref="HSSP:1Q27"
                     /db_xref="InterPro:IPR000086"
                     /db_xref="InterPro:IPR015797"
                     /db_xref="InterPro:IPR020084"
                     /db_xref="InterPro:IPR020476"
                     /db_xref="UniProtKB/TrEMBL:Q53738"
                     /gene="pur7"
                     /product="NTP pyrophosphohydrolase"
                     /protein_id="CAA63159.1"
                     /transl_table=11
                     /translation="MADGTAPKLVVGALISDPLGRIFVQRRSADRRLFPACWDVVGGAV
                     EDGETHHEALAREIAEETGWRLRRVLARVVHESWTADGVRHLESDYVVEVDGDLSSPTL
                     ERDKHPEFAWVGPQDISLLDENVRRGAGTFIKDTVAAGHDWLAGSTRR"
     gene            2713..3729
                     /gene="pur10"
     CDS             2713..3729
                     /codon_start=1
                     /db_xref="GOA:Q53739"
                     /db_xref="InterPro:IPR000683"
                     /db_xref="InterPro:IPR004104"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q53739"
                     /gene="pur10"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     nucleoside: pur10"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 159; E-value: 3.2e-48)"
                     /gene_kind="biosynthetic"
                     /product="Oxido-reductase"
                     /protein_id="CAA63160.1"
                     /sec_met_domain="pur10 (E-value: 6.7e-210, bitscore: 685.3,
                     seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTYSQKRAQPRLRALMVGFAGHQGKEYLPVVREYADIVGGVDVA
                     PAAGALADDWGFPRFTGIGEALKRVDFDVAMVTVPHSEHFPLCRELLLHGKHIVKEKPF
                     AVTEEEARQLIELAEGADRSVYTLLQRNFNPVFQFARKNLARIGDPYWFSYDYHFNLAQ
                     PTSGWRASREQALGGVLLDMGYHLIDVLSGMFPEPSRVNAAFVHHYQEMRDRHLEDLVS
                     LMCSYPSPTLSGSLRISRHNHEKSERLCVLGTGGALNVEPQGATLHSTGGRLLERFTRP
                     GPKTDAVRAMIAHYLGHLDDRDVREDHFRRQLTTVRVIDGIYRERSRERNELADRYS"
     gene            3762..6080
                     /gene="pur6"
     CDS             3762..6080
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q53740"
                     /gene="pur6"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     nucleoside: pur6"
                     /gene_kind="biosynthetic"
                     /product="Synthetase"
                     /protein_id="CAA63161.1"
                     /sec_met_domain="pur6 (E-value: 0.0, bitscore: 1525.1,
                     seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLSITLTRTPGEYLAAALDRPATAPAAVPVLDPTGRHVWPRRIA
                     ARLGLPLTTAHDPDRPAGPAAAAGDATRDEDVLLGAALTELRTGREEHLVVAVAHGDDH
                     AFAHPAAVYALAKRARLLSAANEDDIHRTVRDTAPRFLTLVGPARLLDFGLVTRIRARF
                     PALDVGVLYAHSAAKLSELVLKTLVYPEAPATADVLIAPLLKGDEPLRNGQLTVYPQDA
                     VDAATFTRPAPRPGVATAEPRDPAEPAPMHRLFSVITHGSEDYLRLTSQDILCGLTPDP
                     AEQAAARRESRTLPACMHGGDCVYPDARRWDPAGIPAQIVFANACLTLKLGTQLFGSHN
                     RFTVAQRFLDSWAGTYIASPLLKDGTPGENLLFHYLLDEGATVGGAVRQVNDSLRRWGV
                     DAPEVLVIGDPEARYAPAAARPVPDAVTCQEEPGRAEITFEGRLPAFTRVPLKDPDLRE
                     AHRGGQLRLVPAKPFGGKLPLYGTFGETADGEPAALVFGFQERRLSGTETSRTLTAAPR
                     QRTAADRIVRAVERYENLAALDIKLDKTRSVLTDTANSLPAVARRTKDHIADLTQSEPL
                     HRATERILANCARLDRHLLDTLLRLTETREYHFVEAYRPTYAVEEVRSPYGECRYCGEA
                     THRYTSAHVLRPWLCRLLISCPVCGATQDTEDATVGIAIEGDAVLAPDSTTSLRARITN
                     DGDQELDLLLGARITRGKPHGFRFALSPDRLTVPAGGTATSHLTITTGRPTSLHAMLLR
                     FYAVGLGRIDFAGRDLRFR"
     gene            6137..7426
                     /gene="pur4"
     CDS             6137..7426
                     /codon_start=1
                     /db_xref="GOA:Q53741"
                     /db_xref="HSSP:1MDO"
                     /db_xref="InterPro:IPR000653"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="UniProtKB/TrEMBL:Q53741"
                     /gene="pur4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     291; E-value: 2.4e-88)"
                     /gene_kind="biosynthetic-additional"
                     /product="Amino-transferase"
                     /protein_id="CAA63162.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.1e-102,
                     bitscore: 332.9, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTADKLALLGGTPAIDRPLPHEIWPPRADEAELAALTEQRNTDI
                     SIKGNSGPIGQLEAEFLAFLDHGVRYAVTFNSGTSALLAAYFALGVREGVEVAGPALTY
                     HAALSPVFALRGDVVLVDIDPVSRGLDPKALEAAITENTRVVTVVHQWGHPCDMDAILG
                     VAERYGLRVLEDCSHAHGSRYKGKPVGTFGDAAVFSLQANKAVYAGEGGILVTDDALVQ
                     DRATLLGHYRDRSRDSVIDEELRSHWVTGFGLKLRMSPFNAIVARHSLAAFPARKEARH
                     RCLRHFGELLREVDYLEPITVPDHVDMGAWYGYKPLYRPEALGGVPRSVLIEALRAEGM
                     EVGAPSGPRLATLPLYARPENPLFPGTPKRASAPEPGSQAAHVEQHALSLPTFTDWPED
                     VALIEAYAEAFRKIGRHREALAAHAAETSR"
     gene            7483..8169
                     /gene="pur5"
     CDS             7483..8169
                     /codon_start=1
                     /db_xref="GOA:Q53742"
                     /db_xref="InterPro:IPR007848"
                     /db_xref="UniProtKB/TrEMBL:Q53742"
                     /gene="pur5"
                     /product="N-methyl-transferase"
                     /protein_id="CAA63163.1"
                     /transl_table=11
                     /translation="MTVKESPEAAAKVLEHVMTGDDLPDDFSLLGREWTLHRGVFPGTL
                     TAATEVMASIVPYPKGGSFLEVGCGTGVISVTAALHGSDVTALDINEKAVANTLANAER
                     HGVEDRVRVLHSDLYAALEPTDRFDAIFWNVPWTYVEDGFPLSSDLHSAVFDPGYQGQS
                     RFISGARDHLADGGRLLIGTADLGDRERIDAFAAEAGMTVEMLRRVRRIEVVRVMEYHL
                     LELRAK"
     gene            8253..9074
                     /gene="pur3"
     CDS             8253..9074
                     /codon_start=1
                     /db_xref="GOA:Q53743"
                     /db_xref="HSSP:1IMF"
                     /db_xref="InterPro:IPR000760"
                     /db_xref="InterPro:IPR011809"
                     /db_xref="InterPro:IPR020583"
                     /db_xref="UniProtKB/TrEMBL:Q53743"
                     /gene="pur3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207:inositol monophosphatase (Score: 271.6; E-value:
                     1.4e-82)"
                     /gene_kind="biosynthetic-additional"
                     /product="Mono-phosphatase"
                     /protein_id="CAA63164.1"
                     /transl_table=11
                     /translation="MPQQADLELAMRLADTADRITTRRFQARDCGYARKPDRTPVTDAD
                     TTVEAAVRESVRAARPDDDFAGEETGGEVTAGRTWIVDPIDGTKNFLRGVPVWATLIAL
                     LEDGRPTVGVVAAPALRSRWWAAAGHGAWLRRGSAGAEPLRLHVSGVARLENAYLSTTN
                     TRTWDAFHSRAAYLRLADACWEDRAFGDFLQHCMVAEGTVDIAAEPVVSPWDIAALQIL
                     VEEAGGVCTDLLGGSPQRGTGALSANPELHRLAVEALAAPAAATTGAATIP"
ORIGIN
        1 atcgatgagc tgcggagctg cggcatctgg cagccgcgca acggagtggc gtcggagtgg
       61 gagcactatg tcggccgcct ggccgactcc ttcggtctct cgctcgcctt ctcgggcgcg
      121 gcactgagcg atgagcactt cctggaacac ctgtggagcc acggcgagat ggcgtgcctg
      181 gccggggcgg acgtctccta cgccttctcg ccggacatca ggagcatccc gctcgtcgac
      241 cccacgccgg tctacccgtg gtcgatggtg tggcgtcggc aggcgggcca tccgctcgtc
      301 gaccggctgg tcggtctggc caagcggtcg gccggagact ggctgaccca cgtgcccggg
      361 gagatctggc tgccggcgcc cgaccgggcc ctgctgcgcg gcgcgggggt cgacgtggac
      421 gccgtccggg gctgaaccgg ccatcatcaa gaggcgcgac acgcggcgcc tggcgtgaac
      481 ttgatcgttt gtgcggcgcg cggccggggt atccgagggc gccgccgtcc cggtgcgagg
      541 ccggtagtac gggccgtaag tacgttccaa aacgccatcg gatcactgtg tcaagcccca
      601 gctgagacgt ccggattccg gcgatactct ttacggtttt ttggggcgca agaattgccc
      661 gggtaatgtg ctggtcgttg atgcgaactc acagaagcac cactggatat gggggaaacg
      721 tgcttcaccg gatccagaga aaaagagcga tgaccgcagg cgcggtcggt gtgctctttc
      781 tcgcgcagct tgtgattagt tcctcttcgg ctgcggcggg ggaatccgag gtcaccccgc
      841 cgccgctctc ccaggatcgg atagaaaagc atctgacgcg gttcgagcgc attgcggacg
      901 cgcacggcgg cgaccgtgca tccggcacgc aaggatatgc ggaatcggtc gactacaccg
      961 aaaagctgct caaaaaagcg ggatactcga cgcagcgcca gcaattccct ttccgctaca
     1021 ccaggacgct tgaggaaaag ctggtgctgc gggacggcag cacacccgga gtcgtggtca
     1081 gcggctactc gcagtcgacc ccccgaggcg gcctgacagc acggccgacg gcggtcggcg
     1141 gggacaccga gcggcggcag ggctgccgcg ccggcgcgta cgacggagtg ccggctggcg
     1201 ggcggatcgc gctcgtcgac gccgggggct gctcgatgga cgacaagcag cgggtggccg
     1261 ccgacgccgg cgcggccgcc gtaatcgtcg ccaacaccgg ccccggcgaa ctgcacacct
     1321 ggctggccga ccccgaggcg gcccgcatac ccatcggcgg cgtcacccag gagacgggcc
     1381 gcctcctcgc cgccgaggca cgggccggac gcaccgtcca gctcaccctg cgctcgctca
     1441 ccgaacgccg taccaccgag aacctgatcg ccgtgagccc ccgcggcaac cccgagcaca
     1501 ccgtggtctc cggcgcccac ctcgactccg tgccggaggg gcccggcatc aacgacaacg
     1561 gtgtcgccgc cgccgtactg ctcgaaagcg ccctggcggc cgccaaggac cacggcaccc
     1621 gggccgagga caaccggctg gtgttcggct tctggggcgc ggaggagttc ggcctgctcg
     1681 gctcgcagca ctacgtcgac tcgttgaccc aggaggagcg tgagcgcacc gggctgtacc
     1741 tcaacctgga gatgatcggc agccccaact acggtctctt cacgctggat tccaaggcca
     1801 ccgaccccgt cacaggacag cgcccggccc ccggctcgga cgagatcgag cgcgagctga
     1861 ccgacgcgtt cgccgcccag ggccgcacct ccctgccggg acccgccgac gggcgctccg
     1921 actacgtggc gttcctgggc gcgggcatcc ccaccggcgg gctctacgga ggctcgttcg
     1981 aggccaagac ccccgagcag gccgctctgt ggggcggcac cgctggccgg ccgtacgacc
     2041 cctgctacca cctgacgtgc gacaggacgg cgcagtacag ccgcgaggcg gcgacgctgc
     2101 acgggcaggc gttccagacg gtgctcaccc actactcccg gcaccggctg ggagaggcag
     2161 ccgcccacca tggctgacgg gaccgcgccc aagctggtgg tgggtgcgct catcagcgat
     2221 ccgctcggcc ggatcttcgt acagcgccgc tcggccgacc ggcgcctgtt ccccgcatgc
     2281 tgggacgtcg tgggcggcgc cgtggaggac ggcgagaccc accacgaggc actggcccgg
     2341 gagatcgccg aggagaccgg ctggcggctg cgccgggtgc tggcccgggt ggtgcacgag
     2401 agctggacgg cggacggcgt acggcacctc gagtcggact acgtcgtcga ggtggacggg
     2461 gacctgtcgt cacccacgct cgaacgggac aagcacccgg agttcgcgtg ggtggggccg
     2521 caggacatct ccctgctcga cgagaacgtc cggcgcggcg ccggcacctt catcaaggac
     2581 acggtcgccg ccggacacga ctggctcgcc ggatccacgc gccgctgagc cctcccggcc
     2641 gtcctcaata cttcgttctt cgtcatcgtc accgtcatcg gcagaggcaa tcacgcgagg
     2701 gggaagttcc gcatgtccac ttattcacag aagcgtgcgc aaccgcggct gcgggccctg
     2761 atggtcggat tcgcaggcca ccagggaaag gagtacttac cggtcgtccg ggagtacgca
     2821 gacatcgtcg ggggcgtcga tgtcgcccct gcggcggggg cgctcgccga tgactgggga
     2881 tttccgcggt tcaccgggat cggcgaggca ctcaagcggg tcgacttcga tgtcgcgatg
     2941 gtcaccgtgc cgcacagcga acatttcccg ctgtgcagag aactgctgct gcacggcaag
     3001 cacatcgtca aggaaaagcc gttcgccgtc accgaggaag aggcccggca gctgatagag
     3061 ctggccgaag gagcggaccg cagcgtttac acgctcctcc agcgcaattt caacccggtc
     3121 ttccagttcg cgcggaagaa cctggcccgc atcggcgatc cctactggtt ctcgtacgac
     3181 taccacttca acctggcgca gccgacgagc ggttggcgcg cctcccgcga acaggccctc
     3241 ggcggggtgc tgctcgacat gggctaccac ctcatcgacg tgctcagcgg aatgttcccc
     3301 gaaccgagcc gcgtgaacgc cgccttcgtc caccactacc aggagatgcg cgaccggcac
     3361 ctggaggacc tggtcagcct gatgtgcagc tacccgtcgc cgaccctgtc cggctcgctg
     3421 cgcatctccc ggcacaacca cgagaagtcc gaacgcctct gcgtcctcgg caccgggggc
     3481 gcgctgaacg tggaacccca gggcgccacc ctgcactcca ccggcggccg cctcctcgaa
     3541 cgcttcaccc gccccggacc caagaccgac gcggtccgcg ccatgatcgc ccactacctc
     3601 ggacacctgg acgaccggga cgtacgtgag gaccacttcc gtcggcaact caccaccgtg
     3661 cgcgtgatcg acgggatcta ccgggagcgg tcacgggagc ggaacgaact cgccgatcgg
     3721 tacagctgat cctcaccgtc ccgaggcacc tggagagaaa cgtgacgtta agcatcactc
     3781 tgacgcgcac accgggggag tatctcgccg cggccctgga ccgccccgcc accgcacccg
     3841 ccgccgtccc tgtgctcgac cccacgggcc gccatgtgtg gccccgccgg atcgccgcac
     3901 gcctcggcct gccgctgacc accgcccacg acccggaccg gcccgccggc cccgcggccg
     3961 cggccggtga cgccacccgt gacgaagacg tcctcctggg cgccgccctc accgagctgc
     4021 gcaccggccg ggaggagcat ctcgtcgtgg ccgtcgccca cggcgacgac cacgccttcg
     4081 cccacccggc ggccgtctac gccctcgcca agcgcgcccg gctgctgtcg gcggcgaacg
     4141 aggacgacat ccaccggacc gtacgggaca ccgcgccccg cttcctgacc ctcgtcggac
     4201 ccgcccggct cctcgacttc ggcctcgtca cacggatacg ggcccgcttc cccgccctcg
     4261 acgtcggcgt cctgtacgcg cacagcgccg ccaagctcag cgagctggtc ctcaagacgc
     4321 tcgtctaccc cgaggccccc gccaccgctg acgtgctgat cgccccgctc ctcaagggcg
     4381 acgagcccct gcgcaacgga cagctgaccg tctacccgca ggacgccgtc gacgccgcca
     4441 ccttcacacg gcccgccccc cggcccggcg tcgccaccgc cgaaccgcgg gatccggccg
     4501 aaccggcccc gatgcaccgc ctgttcagcg tcatcaccca cggcagcgag gactacctgc
     4561 ggctcacctc gcaggacatc ctgtgcggcc tcacccccga ccccgccgaa caggccgcgg
     4621 cacggcggga gtcacgcacc ctgcccgcct gcatgcacgg cggcgactgc gtctatcccg
     4681 acgcgcggcg ctgggacccg gccggcatcc ccgcccagat cgtcttcgcc aacgcctgcc
     4741 tcaccctcaa actcggcacc cagctcttcg gcagccacaa ccgcttcacc gtcgcccagc
     4801 gcttcctcga ctcctgggca ggcacctaca tagccagccc gctgctcaag gacggcaccc
     4861 ccggcgagaa cctgctcttc cactacctgc tcgacgaggg cgccaccgtc ggcggcgcgg
     4921 tccgccaggt caacgacagc ctgcggcgct ggggcgtcga cgcacccgaa gtgctcgtca
     4981 tcggcgaccc ggaggcccgc tacgcccccg ccgcggcacg gccggtgccg gacgcggtga
     5041 cctgccagga ggagccgggc cgcgccgaga tcaccttcga ggggaggctg cccgccttca
     5101 cccgcgtccc tctcaaggac cccgacctgc gcgaggccca ccgcggcgga caactgcgcc
     5161 tcgtccccgc caagccgttc ggcggcaaac tgcccctcta cggcacgttc ggcgaaaccg
     5221 ccgacggaga accggccgcg ctggtcttcg ggttccagga acgccggctc tccggcaccg
     5281 agacctcgcg caccctcacc gccgccccac ggcagcggac cgcggccgac cgcatcgtgc
     5341 gcgccgtgga gcgctacgag aacctcgccg ccctcgacat caagctcgac aagacccggt
     5401 cggtgctcac cgacaccgcc aacagcctgc ccgccgtggc ccgcaggacc aaggaccaca
     5461 tcgcggacct gacccagtcg gagccgctgc accgcgccac cgagcgcatc cttgccaact
     5521 gcgcccgcct cgaccggcac ctgctcgaca ccctgctgcg cctcaccgag acccgcgagt
     5581 accacttcgt ggaggcgtac cggcccacgt acgccgtcga agaggtccgc agcccgtacg
     5641 gcgagtgccg gtactgcggc gaggccaccc accgctacac cagcgcccat gtgctgcgcc
     5701 cgtggctgtg ccgcctgctg atcagctgcc ccgtgtgcgg cgccacccag gacaccgagg
     5761 acgccacggt cggcatcgcc atcgaagggg acgccgtcct cgcgcccgac agcacgacct
     5821 cgctgcgggc ccggatcacc aacgacggag accaggaact cgacctgctc ctcggggccc
     5881 gcatcacccg cggcaaaccg cacggcttcc ggttcgccct gagcccggac cggctgaccg
     5941 tccccgcggg cggcaccgcc acctcccacc tgaccatcac caccggccgg ccgacgtccc
     6001 tgcacgccat gctgctgcgc ttctacgccg tcggcctggg gcgcatcgac ttcgcgggcc
     6061 gcgatctgcg gttccgctga ccgcccaccg gcccggcacc ccggagccac gccactcccc
     6121 acgccaggaa ggacccatga ccaccgccga caagctcgcc ctcctcggag gcaccccggc
     6181 catcgaccgg ccgcttcccc acgagatctg gccgccccgc gcggacgagg ccgaactggc
     6241 cgcactcacc gagcagcgca acaccgacat ctccatcaag ggcaacagcg gccccatcgg
     6301 ccaactggaa gccgaattcc tcgccttcct cgaccacggc gtccgctacg ccgtcacctt
     6361 caactccggc accagcgccc tgctcgccgc ctacttcgca ctcggcgtac gcgagggggt
     6421 cgaggtggcg gggcccgcgc tcacctacca cgccgcgctc agccccgtct tcgccctgcg
     6481 cggcgacgtg gtcctcgtcg acatcgaccc cgtcagccgc ggcctcgacc ccaaggccct
     6541 ggaagcggcg atcaccgaga acacccgggt cgtcaccgtc gtccaccagt gggggcaccc
     6601 ctgcgacatg gacgcgatcc tgggcgtcgc cgagcgctac ggactgcgcg tcctggagga
     6661 ctgctcccac gcccacggca gccgctacaa gggaaagccg gtcggcacct tcggcgacgc
     6721 cgcggtcttc tccctccagg ccaacaaggc cgtctacgcg ggagagggcg gcatcctcgt
     6781 caccgacgac gcgctggtgc aggaccgcgc caccctcctc ggccactacc gggaccgctc
     6841 ccgggactcg gtcatcgacg aggagctgcg ctcgcactgg gtgaccggct tcggcctgaa
     6901 gctgcggatg tcgccgttca acgcgatcgt cgcccggcac tcgctcgccg ccttccccgc
     6961 ccgcaaggag gcccggcacc gctgtctgcg ccacttcggc gagttgcttc gcgaggtgga
     7021 ctacctggag cccatcacgg tccccgacca cgtcgacatg ggcgcctggt acggctacaa
     7081 gcccctctac cggcccgagg cgctgggcgg cgtcccgcgc tccgtactga tcgaggccct
     7141 gcgggccgag ggcatggagg tcggcgcgcc gtccggcccc cggctggcca ccctgccgct
     7201 gtacgcgcgg ccggagaacc ccctcttccc cggcaccccc aagcgcgcca gcgcaccgga
     7261 gcccggctcg caagccgccc atgtcgagca gcacgccctg tccttgccca ccttcaccga
     7321 ctggcccgag gacgtggcgc tgatcgaggc ctacgccgag gccttccgca agatcggacg
     7381 gcaccgggag gcgctggccg cccacgccgc cgagacctcc cggtgacccc cggcaccccg
     7441 acagcttcca cgatcccgtc accctcacag gaaaggtcaa ccatgactgt caaggaatcc
     7501 cccgaggccg ccgccaaggt cctcgagcac gtcatgaccg gggacgacct gccggacgac
     7561 ttctccctgc tgggccgcga gtggaccctg caccgcggcg tcttccccgg caccctgacc
     7621 gccgccaccg aggtcatggc ctcgatcgtg ccctatccca agggcggctc cttcctggag
     7681 gtcggctgcg gcaccggcgt catctccgtg accgcggcgc tccacggcag cgacgtcacg
     7741 gcgctcgaca tcaacgagaa ggcggtggcg aacaccctcg ccaatgccga gcggcacggc
     7801 gtcgaggacc gggtgcgggt gctgcacagc gacctgtacg cggcgctcga acccaccgac
     7861 cggttcgacg cgatcttctg gaacgtgccc tggacgtacg tggaggacgg cttcccgctc
     7921 tccagcgacc tgcactccgc ggtcttcgac cccggctacc agggccagtc ccggttcatc
     7981 tccggggccc gcgaccacct ggccgacggc ggccggctgc tgatcggcac ggccgatctg
     8041 ggagaccgcg agcggatcga cgccttcgcc gccgaggccg ggatgaccgt cgagatgctg
     8101 cgccgcgtac gccgtatcga ggtcgtccgg gtcatggagt accacctgct cgaactgcgc
     8161 gccaagtgag ccggccgccc cggcggcgca cttcccccgg cccgccgggg cggccccccg
     8221 accccgtgtc ccgtcgagga ggaggcacct tcatgccaca gcaggccgac ctggaactgg
     8281 ccatgcgact cgccgacacc gccgaccgca tcaccacccg ccgcttccag gcgcgcgact
     8341 gcggatacgc gaggaagccc gaccgcaccc ccgtcaccga cgcggacacc accgtcgagg
     8401 cggccgtacg cgagtccgtg cgggccgccc ggcccgacga cgacttcgcg ggagaggaga
     8461 ccggcggcga ggtgaccgca ggacgcacct ggatcgtcga ccccatcgac ggcaccaaga
     8521 acttcctgcg cggagtgccg gtctgggcca cgctgatcgc gctcctggag gacggcaggc
     8581 ccaccgtcgg cgtcgtcgcc gcgcccgccc tgcgcagccg ctggtgggcg gcggccgggc
     8641 acggggcctg gctgcggcgc gggtccgccg gcgccgaacc gctgcggctg cacgtctccg
     8701 gtgtcgcccg cctcgaaaac gcctatctgt ccaccaccaa cacccgtacc tgggacgcct
     8761 tccactcgcg cgcggcgtat ctgcgactcg ccgacgcctg ctgggaggac cgcgccttcg
     8821 gcgacttcct ccagcactgc atggtcgccg agggcacggt cgacatcgcg gccgaaccgg
     8881 tcgtgagccc ctgggacatc gccgccctcc agatcctcgt ggaggaggcg ggcggcgtct
     8941 gcaccgacct gctcggcggc tcgccccagc gcgggacggg tgccctgtcc gccaacccgg
     9001 agctgcaccg gctcgccgtg gaggccctcg ccgcccccgc ggccgccacg accggtgccg
     9061 ccaccatccc ctgacccacg cccctgaccc ctcacaagga gacgaccttc catgaccgag
//
