LOCUS       BGC0000882             19814 bp    DNA     linear   BCT 14-MAR-2012
DEFINITION  Streptomyces rimofaciens strain ZJU5119 mildiomycin biosynthetic
            gene cluster and flanking regions, complete cds.
ACCESSION   BGC0000882
VERSION     BGC0000882
KEYWORDS    .
SOURCE      Streptomyces rimofaciens (Streptoverticillium rimofaciens)
  ORGANISM  Streptomyces rimofaciens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     On Mar 14, 2012 this sequence version replaced EU328345.1.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 14:22:09
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 6124
            Orig. end    :: 25938
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..1005
                     /gene="milA"
     CDS             1..1005
                     /codon_start=1
                     /gene="milA"
                     /note="MilA"
                     /product="CMP 5-hydroxymethylase"
                     /protein_id="ACA14348.1"
                     /transl_table=11
                     /translation="METHTFGTFQDAYLSQLRDIYHSPEFRNAPRGQASRERIGAGFRL
                     LDPVQRHISVPARRANVVFNFAEALWYLSGSDRLDFIQYYAPGIAAYSADGRTLRGTAY
                     GPRIFRHPAGGVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLI
                     RDGLLCGIGYMRANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIYDSDA
                     RWAERVLDAATPDGGPRPGFPAMPDGDNWPHVRRVLEWEERLRTNAARLSADALDALDL
                     PAYWKHVVALFEAHRQVRHEDTPDRALLAALPEVYRQSLAVKWPGHFGSPAGS"
     misc_feature    1..19814
                     /note="mildiomycin biosynthetic gene cluster"
     subregion       1..19814
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..19814
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1128..1640
                     /gene="MilB"
     CDS             1128..1640
                     /codon_start=1
                     /gene="MilB"
                     /note="BlsM-like protein"
                     /product="CMP/hydroxymethyl CMP hydrolase"
                     /protein_id="ACA14349.1"
                     /transl_table=11
                     /translation="MTTTPKPRTAPAVGSVFLGGPFRQLVDPRTGVMSSGDQNVFSRLI
                     EHFESRGTTVYNAHRREAWGAEFLSPAEATRLDHDEIKAADVFVAFPGVPASPGTHVEI
                     GWASGMGKPMVLLLERDEDYAFLVTGLESQANVEILRFSGTEEIVERLDGAVARVLGRA
                     GEPTVIG"
     gene            1782..3044
                     /gene="milC"
     CDS             1782..3044
                     /codon_start=1
                     /gene="milC"
                     /note="MilC; BlsD-like protein"
                     /product="cytosylglucuronic acid/hydroxymethyl
                     cytosylglucuronic acid synthase"
                     /protein_id="AFD20743.1"
                     /transl_table=11
                     /translation="MAGAEFGWGSAGKLAAIVAALRERHGERVRFAGLGSGLGRPVLGA
                     LDARDWTDVPEPGDGPAGEAALAALLRERGVDAAVVVLDGLLAARLEAVGCPVVYVDSL
                     PFLWTEHDFVPSGVHTYCAQLCPSLPRQSWPVLRGIEALRWVEPVVGTYGAGGLDPVPG
                     KAVLNVGGLRSPFTAEDDDSYVELVLGPALRALRAAGFGQVVISGNVDPGLARVPHAGT
                     HGLTVTAGRLDHGAFIEELRTAELLVTSPGRTTLLEAAALGQRAVVLPPQNFSQVMNAA
                     DVADLVDPAVVVPWPAAVLDLAELARVRDQGEEGAVRLMYARIAAARREPGTVAGPLAD
                     ALGAAVAHVRRHDVRMGPFAGTDGSGAGTRGAGGARDTGGAGGARSVADAVDELIGKLT
                     DGPAAGNRRDGSPLAAPVRAR"
     gene            3061..4248
                     /gene="milD"
     CDS             3061..4248
                     /codon_start=1
                     /gene="milD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     182.9; E-value: 1.7e-55)"
                     /gene_kind="biosynthetic-additional"
                     /note="MilD; BlsH-like protein"
                     /product="degT/dnrJ/eryC1/strS aminotransferase"
                     /protein_id="AFD20744.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.4e-55,
                     bitscore: 179.1, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRHPRELRQDTSLAINGGTPTFAALPEEDTGIVAEAADEVAELIR
                     TRRTVHWGGGPHTRVLERDFAALVGRERAFFHNSGTAALQTALFALEVEEGTPVALSDS
                     GFVASLNALYHLRARPVFLPTHPATLQCVDDVAEWTAGTGVHTALITHFFGNVADVEAI
                     WRTSGARHLVEDGGQAHGARLRGRPVGSFGTVGSFAGSTKKLVTAGQGGLNVHDDEHLD
                     WRMRTYAHHGKSGNYEGTFPGYNFRGGEMEAILAHAALRRLDERVAARNRTADTMFRIF
                     DEAGIRTARPAPGLDCSPAWFDVALILDEEWLGHRDWLVEAMVADGIPGWHYPALIGMP
                     WVEPWMRSKGWWGEREQELLASETALWGRTLVLGAQMNAVDAERIAHAVVALLKG"
     gene            4256..5077
                     /gene="milE"
     CDS             4256..5077
                     /codon_start=1
                     /gene="milE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /note="MilE"
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="AFD20745.1"
                     /sec_met_domain="APH (E-value: 6.1e-20, bitscore: 62.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTCGEISEVRRVLRRLGDGGPRSVRVRENGNCAVYVGDRLVVRVG
                     HSWPLDARGELHCWSVARDAGVPAPERIDEGRLPGGRTYVAYVYVMGTPAGTPASLAAA
                     GAVLARLHTVPGEHFPAVAHNLPRRRDRYRTAVRCARAAGLAPGGLAHRCLLRAADDWR
                     RSREVAAHGDFRTPNLVVRGRGVRAVLDWSDARAASPESDLGQLGPGQLRPLLRGYLDR
                     ARRAPDLELVAGHMLARHLALEAAGVFPAGTSAALARRFGPGLSRGRWTVA"
     gene            5070..5543
                     /gene="milF"
     CDS             5070..5543
                     /codon_start=1
                     /gene="milF"
                     /note="MilF"
                     /product="hypothetical protein"
                     /protein_id="AFD20746.1"
                     /transl_table=11
                     /translation="MPDRSPAAEPLILDVGSAGQLAELAGDLVDLAGPGGATGPWVLTW
                     AHGAGEPGGEPGEGQNRGPNGGTGGGPGGTVARPPGATVVRHGGLEVVTVPRPPRDLGG
                     FLDACCRTGPVSGHPDVTRTILILADPTDRDRSASPPEAPHDAPRDGARDGRP"
     gene            5503..6510
                     /gene="milG"
     CDS             5503..6510
                     /codon_start=1
                     /gene="milG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /note="MilG; BlsE-like protein"
                     /product="radical SAM superfamily"
                     /protein_id="AFD20747.1"
                     /sec_met_domain="PF04055 (E-value: 3.2e-21, bitscore: 66.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.5e-08, bitscore: 23.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHPATGPATGGRDRYLFIRILEACNADCFMCEFALSRDTYRFTL
                     DDFRELLPQAQESGVRYVRFTGGEPLMHGEVLDLIREGTAAGMRMSLITNGFRLPQMVD
                     KLAEAGLAQVIVSLDGSSGETHDVYRRTPGMFDRGLDGLVRASRAGMLTRVNTVVGPHN
                     FAQMPELQRVLTEARVEQWEMSALKLERHIAYPPAEEVLHACEPVFLADPKRWLVPLGK
                     RFYGETAEEREAFFERGTTPSASRPLCHVTDDVMYLDPKLGRTFACSCLPHRDGPGADM
                     RDERGRVFLNSPSFRAHAEEFKQQGPVICSGCSTTAAGYSDDVARLGSVPAWHY"
     gene            6605..8827
                     /gene="milH"
     CDS             6605..8827
                     /codon_start=1
                     /gene="milH"
                     /note="BlsK-like protein"
                     /product="MilH"
                     /protein_id="AFD20748.1"
                     /transl_table=11
                     /translation="MILRTDHVDAYLSAVSAILDEPGRAGAGVPVLCRPGSPLDVLVTR
                     WSALLGHAGPRARSDRPGRAVVAVGDDPVVSAAARLLAVLTGRTALAVADVKELPALWE
                     RHDLVSTALVGIGTGFDVPGVEPSAFWRLDATDATLGILTGRDRESLTWFVAKSLLTST
                     VPGDAQTLLLPDRKPREDTASAGVGAGGVEVLYGAAAEEALPALAEDERVRALIAVEAH
                     GRADHLGVRDGIICGDRLAHLGRSSEPEGIGRVPQCAFGHGCFKPGARVAISRMPAQSL
                     FLHSCTSSHTEADMYEKSFLLGLAALEGPARHVLGTVRPMHDGGHEVGLVSALTAAGAS
                     AGEVTRLLNASYHQHRGEPAPYLLLGDPELPFADGPVGGPDAGPAVELDASAGALPLGG
                     RRTAVLGSGPGVLVVGDATGDEDGDGPGLPAGVGALTVRRGDRTDVVAWSTEGPLPEGA
                     LPLVRREGGAVAADGGAEELHARWDHVDHGIASGGALGLLPKDLTGRLQELRDLAAAVG
                     TADRDARFFPGRLGAVRRAAARLDQRIRDADRALMHALLGRNGKPFDADDRLESAFVPL
                     ESQYGRQVCWCGRDAVVSRLRPRLGAREVRRKYNCMQCGDYAQVAVDGVDVRWEAPEFV
                     ASGGELEHSFRIANPLPHPVTGVLALSVSPWYGGDVSFRPGIATFSVAPGGTCRVGVTM
                     RAAGLKPHRYTVDATVVSHLRINAYRKFVQVRPAGPVGPSDEDGAL"
     gene            8824..9906
                     /gene="milI"
     CDS             8824..9906
                     /NRPS_PKS="Domain: PP-binding (57-108). E-value: 4.3e-07.
                     Score: 22.3. Matches aSDomain:
                     nrpspksdomains_milI_PP-binding.1"
                     /codon_start=1
                     /gene="milI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /note="MilI"
                     /product="chitinase A precursor"
                     /protein_id="AFD20749.1"
                     /sec_met_domain="PP-binding (E-value: 1.3e-07, bitscore:
                     22.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPTTGPTTGPTTGPTAGPTTGPTAGPTAGPTAGSAVAEEAVAE
                     WAAAWLEQVHGVRYGPDDALFGSLDSLALTELLVACEAHFGLRIDEGFGWQALASVRSL
                     AAHVATGVRPPSDRVWFRSGPGATGDADLDRTAVVRVALGLPPGAAVARLSPRELALGI
                     GAAAAPSEKPATTLPPERERLSLARESSTRPGSLLAVGATAARIRAFAGRLDAALAAVG
                     ATPVWYPITTDSPVGADHVQGIPSELTAGRLGHAGCLQLLAELPAERDVVYSGIAYAFR
                     DEPGRRWEPAGRLEAYRVHETVVHGTEEFRTAMWRRLYELVDRELSALGPGGWQEGRDG
                     FTPRHGPQARMAAGTRRWAR"
     aSDomain        8995..9147
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_milI_PP-binding.1"
                     /evalue="4.30E-07"
                     /label="milI_PP-binding.1"
                     /locus_tag="milI"
                     /protein_end="108"
                     /protein_start="57"
                     /score="22.3"
                     /tool="antismash"
                     /translation="RYGPDDALFGSLDSLALTELLVACEAHFGLRIDEGFGWQALASVR
                     SLAAHV"
     gene            10078..11031
                     /gene="milJ"
     CDS             10078..11031
                     /codon_start=1
                     /gene="milJ"
                     /note="MilJ"
                     /product="predicted protein"
                     /protein_id="AFD20750.1"
                     /transl_table=11
                     /translation="MDAAPGTARTAAGTSVPPVLPVDAERPAARRTLAMEEGTPRQWEG
                     LGLHGVPEAVEAALGPAAELVVAARGGGRSPLPGLVFAQPCLGRSAGVARDLPVSVVWE
                     TGVALAIARALDRPAVIGLCVYEEILQQPHRDAEFTALGAAVARTVEALGRLLGVAVTA
                     RVETAAPRAAEVPARRLYGLYTPFSESTYPRGFPNEAEVLRAFSAYCGRYEDAARREAS
                     LWVTEGVHLAKAALLGLGPGVPFLATTPLPDPAHPGRLLQDAPAATRVTLERRSALPAD
                     WWPEQALERALGTGLRRLTEDFHALIEDFHDPAGDR"
     gene            11028..12356
                     /gene="milK"
     CDS             11028..12356
                     /codon_start=1
                     /gene="milK"
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 56.1; E-value: 3.8e-17)"
                     /gene_kind="transport"
                     /note="MilK; BlsJ-like protein"
                     /product="major facilitator superfamily"
                     /protein_id="AFD20751.1"
                     /transl_table=11
                     /translation="MRTPRTGAVLGGRGPALPFVAYMALSNAQFTRGVFVLFLLRGNIS
                     LAEVGLLESLFHLTRVLCEVPAGSVADRWGRRRTIQAGLILSAAAMPAFLLGGMFWYAL
                     AFVFQGAGWAAQRGADTALLYELLERTGGTDRYARILGRSHAASYGTLALTTALGAMLY
                     QRHVSLPFWLQAAVTLLAVGAIGVLPESSGTAASGAGSSGSGSSGEPAERPMGVWRLAR
                     AGARLVVGHPVLRLFVAFVALVEAGTTVVSIFSQSFFRTLGYGTATTGLILALVTAFSA
                     AAALQSHRLVERGPVRVLMAASSLYLVGLAGMASLQPQLAVVGYYLVFLNLDLLAPVLS
                     AFFHRSVDEEVRATAGSYLNLSTSVLTFAAFPLSGSLIDAGGYRPLLIITALVSLPLLV
                     FLVGAARRVLSPPEEGDSGEDAGERAGPKGPGAAAPDTTTTGV"
     gene            12364..13350
                     /gene="milL"
     CDS             12364..13350
                     /codon_start=1
                     /gene="milL"
                     /note="MilL; BlsF-like protein"
                     /product="hypothetical protein"
                     /protein_id="AFD20752.1"
                     /transl_table=11
                     /translation="MTTRADSPSPGSGGPVGPGGSGGDDGRPVIALRFAPADVEAAAAA
                     EYVAAHLGGFRCLPECPQEGDSGPGRNPPAAVIVFGRSGAAGGAGPAGVPTVLVEGAEP
                     VPGTDADVVCRQAPGWLTAGEPPAPPAVRPGGGRIRTVDVAAVAPFRQVRSGGGGGRAA
                     LLLGGAGGPDGSGASAGGEALPGALARFIAGHPAAAGDAWAVLTDLTGEPLRELLGLLP
                     PTARTVGAADWAQVLRRADSLVATPTLLAAAHARTARIPLHVLDPAGPAQRRVHRALAA
                     IAGAPGEPGGLPVVGPDDWPRDDGRAGALGGAAQIARQVRQLCLAPA"
     gene            13424..14593
                     /gene="milM"
     CDS             13424..14593
                     /NRPS_PKS="Domain: Aminotran_1_2 (65-374). E-value:
                     4.9e-09. Score: 27.6. Matches aSDomain:
                     nrpspksdomains_milM_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="milM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 76.1; E-value: 4.3e-23)"
                     /gene_kind="biosynthetic-additional"
                     /note="MilM"
                     /product="Aspartate/tyrosine/aromatic aminotransferase"
                     /protein_id="AFD20753.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.5e-09, bitscore:
                     27.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDTLAHNRPLDLTQHEIAALRSEHNLADAHTHQYQSPAQQLIVD
                     SLPALWHEAEKGRQADFEQRFIEAFFRLHGQPTAIGLDRTLLTYAASISTMIAGMFLKR
                     RDARVTLVEPCFDNLPDLLVNLGVPLTALPEDALRDPARIHRELSRLVTTEALFLVDPN
                     NPTGHSLFADGMRGFEEVVRFCRERGTVLVLDLCFAAFALGSGGPGRHDVYELLENSGV
                     TYIAMEDTGKTWPVQDAKCALLTTSADIYPAVYNLHTSVLLNVSPFILNTLTRYIEDSR
                     RDGFASVTDVLERNRKSLRAATEGTVLRAHEPDVPVSVAWFTIDDRGPDATQLQRDLSG
                     HGIHVLPGTYFYWNEPSRGERYVRVALARDPGEFDASMARLRTLLARYA"
     aSDomain        13619..14545
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_milM_Aminotran_1_2.1"
                     /evalue="4.90E-09"
                     /label="milM_Aminotran_1_2.1"
                     /locus_tag="milM"
                     /protein_end="374"
                     /protein_start="65"
                     /score="27.6"
                     /tool="antismash"
                     /translation="FIEAFFRLHGQPTAIGLDRTLLTYAASISTMIAGMFLKRRDARVT
                     LVEPCFDNLPDLLVNLGVPLTALPEDALRDPARIHRELSRLVTTEALFLVDPNNPTGHS
                     LFADGMRGFEEVVRFCRERGTVLVLDLCFAAFALGSGGPGRHDVYELLENSGVTYIAME
                     DTGKTWPVQDAKCALLTTSADIYPAVYNLHTSVLLNVSPFILNTLTRYIEDSRRDGFAS
                     VTDVLERNRKSLRAATEGTVLRAHEPDVPVSVAWFTIDDRGPDATQLQRDLSGHGIHVL
                     PGTYFYWNEPSRGERYVRVALARDPGEF"
     gene            14586..15362
                     /gene="milN"
     CDS             14586..15362
                     /codon_start=1
                     /gene="milN"
                     /note="MilN"
                     /product="dihydrodipicolinate synthetase family protein"
                     /protein_id="AFD20754.1"
                     /transl_table=11
                     /translation="MREPGLIAPLVTPLTPDGAVSEACVRAQVARVRPYVRALMPGISC
                     GEGWLLDRPRWERLAAAVLDCRDGLPVHLGVQAADTAEVIRRARWAVRHGADAVTVGPP
                     HGAGARQRAVHEHFARVCAAVDTPVCVYHESVVSGTRMTPATLTAVCRLDGVRAVKESG
                     REPSVTNDLIAAVPDVAVHQGWEDLFHATPGAAGLIGPLVLIDPALCAELVAGVGGVQG
                     VVTDRCRELGLFRPDYVARTKRELCRLGVLAHAVTL"
     gene            complement(16095..17165)
                     /gene="milO"
     CDS             complement(16095..17165)
                     /codon_start=1
                     /gene="milO"
                     /note="MilO"
                     /product="regulatory protein LuxR family"
                     /protein_id="AFD20755.1"
                     /transl_table=11
                     /translation="MCPLTEARLTGRARAVYLEILRAGGSLPRTALRTPGPPEHSGEGT
                     DADGDHELTEAIDALVALRLIQHTDRGRLLAAISPQSAAAALSAVREGEIQRQRLEDER
                     LRSAMASLQDAYDAVNEGRARKAPQIESLTDISTIRGLLSAAARDCRHEVLTAQPEALL
                     ESTLADSRPRDLSLLTRGIAIRTVYPHTVLSSPAVQQHFSLMHEAGTQIRTTTGVLDRV
                     VIFDQSLAFLADRRSDGPGAVVIRHPAVVDYLYRTIEQVWRLAKPFVYTHVGYGPAADE
                     IRAGILRLMAAGAKDEVIAKRMNMSTRTCRRHIAEMMAELGAESRFQAGVLAADRGLLR
                     LSGGPPPLRGFRGLSG"
     gene            complement(17171..18754)
                     /gene="milP"
     CDS             complement(17171..18754)
                     /codon_start=1
                     /gene="milP"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 72.3; E-value:
                     8.7e-22)"
                     /gene_kind="transport"
                     /note="MilP"
                     /product="ABC transporter superfamily"
                     /protein_id="AFD20756.1"
                     /transl_table=11
                     /translation="MKVALVGPNGAGKTTLLRMIAGDLPVTRGAVARSGGLGVMRQFIG
                     MVSDETTLAGLALSLSPAGLRGAGEALARAETAMAVPGAGEKAQLRYAEALVAWGDAGG
                     YEQEVVFDTVVTDILGTPWDEARSRPVRTLSGGEQKRFALSLLLAGPDEVLLLDEPDNF
                     LDVPGKRRLEARLAESPKTVLYVSHDRELLANTASRVVTVEGGSAWMHPGSFASWHDAR
                     VSRYERFEEERRRWDEEHAKLKELVRHYQVKASHNDAMASRLQAARTRLAKFEAQPPPP
                     PRPREQNIRMRLTGDRTGKRAVVCERLGLDGLTDPFGFEAWYGDRIAVLGANGTGKSHF
                     LRLLGRGGSDPELPSLTPLEPVAHTGSARLGARVVPGHFSQTHDRPELVGRTLEDILWK
                     GDVRRDSLPRDEAMAALGRYELAGQGGQRFETLSGGQQARFLILLLELSGATLLLLDEP
                     TDNLDLASAEALEQGLAGFRGTVLAVTHDRWFTRSFDRFLHFRGDGAVKEVTAPVWEPA
                     VVEGAGQAGR"
     gene            19044..19814
                     /gene="milQ"
     CDS             19044..19814
                     /codon_start=1
                     /gene="milQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /note="MilQ"
                     /product="Aminoglycoside phosphotransferase"
                     /protein_id="AFD20757.1"
                     /sec_met_domain="APH (E-value: 3.5e-14, bitscore: 43.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEDGGSARGSVTTVRRVGDTVRRPRGRWTANVHALLRHLADAGF
                     LRAPRALGVDEDGSEILSFLDGEVAMRPWPAALRERSGVVELAVWLREYHDVVRDFRPP
                     CPDEWFVPGVSWRPGRLVRHGDLGPWNSVWRGSRLVGFIDWDFAEPGDPLDDLAQLAWY
                     CVPLGGRATGAGGEESRVRVRERLAAVCTAYGAEPVSVLDALAGLQEREARRITDLGGR
                     GLEPWTSFLARGDATAIEEERAWLLTHREGLLVG"
ORIGIN
        1 atggaaaccc atacgttcgg gacgttccaa gacgcttatc tgagccagct gcgcgacatc
       61 taccactcac cggaattccg taacgcaccg cgtggacagg cgagtcgcga acggatcggc
      121 gccggattcc ggctgctgga tcccgtgcag cgccacatat ccgtgccggc ccggcgcgcc
      181 aacgtcgtgt tcaacttcgc cgaggcgctc tggtacctct ccggctccga ccgcctcgac
      241 ttcatccagt actacgcgcc cggcatcgcg gcctattcgg ccgacgggcg gaccctgcgg
      301 ggcaccgcct acgggccccg tatcttccgc cacccggcgg gcggggtgaa ccagtgggag
      361 aacgtcgtca agacgctgac ggacgacccc gacagcaaac gggccgtcat ccagatcttc
      421 gacccccggg aactggccgt cgccgacaac atcgacgtcg cctgcaccct ggccctgcaa
      481 ttcctgatcc gcgacgggct gctctgcggc atcggctaca tgcgggcgaa cgacgccttc
      541 cggggcgccg tgagcgacgt cttctccttc actttcctgc aggaattcac ggcccgctat
      601 ctcgggctcg gtatcggcac gtaccaccac gtcgtggggt ccgtgcacat ctacgacagc
      661 gacgcccggt gggcggagcg ggtgctggac gccgcgacgc cggacggcgg cccgcggccc
      721 ggcttccccg ccatgccgga cggcgacaac tggccgcacg tccgccgtgt actggagtgg
      781 gaggaacgcc tccgcacgaa cgcggcgcgc ctctcggcgg acgccctgga cgccctggac
      841 ctgcccgcct actggaagca cgtcgtggcg ctgttcgagg cccaccgtca ggtccggcac
      901 gaggacacgc ccgaccgggc gctgctcgcc gcgctgcccg aggtctaccg gcagtcgctg
      961 gccgtcaaat ggcccggcca cttcggctct ccggccggct cctgaccccg atcggctcct
     1021 gacctcggtc cgttcccgac cccggtccgt tcccgaccgt tcgccgggca cgcccggacg
     1081 acgcgacccc accagagacg cgaccccacc agaaaggaac aaccccggtg accaccaccc
     1141 ccaagccccg taccgccccc gcggtcggct cggtcttcct cggcgggccg ttccgccagc
     1201 tcgtcgaccc ccgcaccggt gtgatgagca gcggtgacca gaacgtcttc agccgcctca
     1261 tcgagcactt cgagagccgc ggcacgacgg tctacaacgc ccaccgccgc gaggcctggg
     1321 gcgccgaatt cctgtcgccc gccgaggcga cccggctcga ccacgacgag atcaaggccg
     1381 cggacgtctt cgtcgccttc cccggcgtcc cggcctcccc cggcacccat gtggagatcg
     1441 gctgggcgag cggcatgggc aagcccatgg tcctgctgct ggagcgcgac gaggactacg
     1501 cgttcctggt caccggtctg gagagccagg ccaatgtgga gatcctccgg ttctccggca
     1561 ccgaggagat cgtcgagcgg ctggacgggg ccgtcgcccg ggtgctgggc cgggcgggcg
     1621 agccgacggt catcggctga ggcgcggccc gcatggacct cttatcggcg gcccgggcgg
     1681 accgggcgga tcggtcggac caggcggatc ggccgactcg gccggacgga gcggatcggg
     1741 cggactggac ggctcgggcg gacggacccg tgaccctggc ggtggcgggt gccgagttcg
     1801 gctgggggag cgcggggaag ctggccgcga tcgtcgccgc gttgcgcgaa cggcacggcg
     1861 agcgggtccg gttcgccggc ctgggctccg ggctcgggcg ccccgtgctg ggcgccctgg
     1921 acgcccgcga ctggacggac gtgccggagc cgggcgacgg cccggcgggc gaggccgcgc
     1981 tggcggcgct gctgcgcgag cggggcgtgg acgcggcggt cgtcgtcctc gacggcctgc
     2041 tggcggcccg gctggaggcg gtggggtgtc ccgtcgtcta cgtcgacagc ctgcccttcc
     2101 tgtggaccga gcacgacttc gtcccgtccg gagtccacac ctactgcgcg cagttgtgcc
     2161 cctcgctgcc ccggcagagc tggcccgtgc tgcgcgggat cgaggcactg cgctgggtgg
     2221 aaccggtggt gggcacgtac ggggccggcg gcctcgaccc ggtgccgggg aaggccgtgc
     2281 tcaacgtcgg cggcctgcgc tcgccgttca ccgccgagga cgacgactcc tatgtggagc
     2341 tcgtcctggg ccccgccctg cgggcgctgc gggcggcggg cttcggacag gtcgtgatca
     2401 gcggcaatgt ggatcccggc ctggcccggg tgccgcacgc cggtacgcac gggctgaccg
     2461 tgacggcggg gcggctggac cacggcgcgt tcatcgagga actgcgcacg gcggagctgc
     2521 tggtgacctc gccgggccgc accaccctgc tggaggcggc ggcgctcggc cagcgggccg
     2581 tcgtcctgcc cccgcagaac ttcagccagg tcatgaacgc cgcggacgtc gcggacctgg
     2641 tggacccggc cgtcgtggtc ccctggccgg ccgccgtcct ggacctggcc gagctggccc
     2701 gggtccgcga ccagggcgag gagggcgcgg tgcggctgat gtacgcccgt atcgccgcgg
     2761 cgcgccggga gccggggacg gtggccggcc cgctggccga cgcgctcggc gccgccgtcg
     2821 cccacgtccg ccggcacgac gtccgcatgg ggccgttcgc cggcacggac gggagcggcg
     2881 cgggaacgcg aggcgcggga ggcgcaagag atacaggagg cgcaggagga gcgcggagtg
     2941 tggcggacgc cgtcgacgag ctgatcggga agctgacgga cggcccggcc gccgggaatc
     3001 gcagggacgg atcaccactg gcggcgccgg tccgggcgcg ctgagggaga gaaggaagcg
     3061 atgcggcacc ccagggaact caggcaggac acctcgctcg cgatcaacgg ggggaccccc
     3121 acgttcgccg cgctcccgga ggaggacacc gggatcgtgg ccgaggccgc cgacgaggtg
     3181 gcggagctga tcaggaccag gcgcaccgtc cactggggcg gcggccccca cacccgcgtc
     3241 ctggaacggg acttcgcggc cctcgtcggc cgggagcgcg cgttcttcca caactccggc
     3301 acggcggccc tgcagaccgc cctcttcgcc ctggaggtcg aggagggcac ccccgtcgcc
     3361 ctcagcgact ccggtttcgt cgccagtctc aacgccctct accacctccg ggcgcggccg
     3421 gtcttcctgc ccacccaccc ggccacgctg cagtgcgtcg acgacgtcgc ggagtggacc
     3481 gccgggaccg gcgtccacac ggcgctgatc acccacttct tcggcaacgt cgccgacgtc
     3541 gaggcgatct ggcgcacctc cggggcccgg catctggtcg aggacggcgg ccaggcccac
     3601 ggcgcgcggc tgcggggccg gccggtcggc tccttcggga ccgtcggctc cttcgcgggc
     3661 tcgacgaaga agctggtcac cgccgggcag ggcgggctga acgtccacga cgacgagcac
     3721 ctggactggc ggatgcgcac ctacgcgcac cacggcaagt ccgggaacta cgaagggacg
     3781 ttccccggct acaacttccg gggcggggag atggaggcga tcctcgccca cgccgccctg
     3841 cggcgcctgg acgagcgcgt cgcggcccgc aaccgcaccg ccgacacgat gttccggatc
     3901 ttcgacgagg ccgggatccg caccgcgcgc ccggcgcccg gactcgactg ctcgcccgcc
     3961 tggttcgacg tcgcgctgat cctcgacgag gagtggctgg gccaccgcga ctggctggtc
     4021 gaggcgatgg tcgccgacgg catccccggc tggcactacc cggcgctgat cggcatgccc
     4081 tgggtcgagc cgtggatgcg atccaagggc tggtggggcg agcgcgaaca ggagctgctc
     4141 gcctcggaga ccgcgctgtg gggccgcacc ctcgtcctcg gcgcccagat gaacgccgtg
     4201 gacgccgagc ggatcgccca cgccgtcgtg gcgctgctca agggatgaca cggcgatgac
     4261 ctgcggcgag atctccgagg tgcgccgggt gctgcgccgg ctcggcgacg gcgggccgcg
     4321 ttccgtccgg gtcagggaga acgggaactg cgcggtgtac gtgggggacc ggctcgtggt
     4381 gcgcgtcggc cactcctggc cgctggacgc ccggggcgag ctccactgct ggagcgtcgc
     4441 ccgggatgcg ggggtgcccg cccccgagcg gatcgacgag ggccggctgc ccggcgggcg
     4501 tacgtacgtg gcgtacgtgt acgtcatggg caccccggcc gggacgcccg cctccctcgc
     4561 ggccgcgggc gccgtgctgg cgcggctgca cacggtgccg ggcgagcact tcccggccgt
     4621 ggcgcacaac ctgccccggc gcagggaccg ttaccgcacg gcggtgcggt gcgcgcgggc
     4681 cgccgggctc gcgcccggcg gcctcgccca ccgctgtctg ctgcgcgcgg cggacgactg
     4741 gcggcggtcg cgggaggtgg ccgcgcacgg cgacttccgc acgcccaacc tggtggtccg
     4801 gggccggggg gtgagggccg tcctggactg gagcgacgcc cgcgccgcca gccccgagag
     4861 cgatctgggc cagctcgggc ccgggcagct gcgcccgctc ctgcggggct atctggaccg
     4921 tgcccggcgc gccccggacc tggagctggt ggccgggcac atgctggccc ggcatctcgc
     4981 cctggaggcc gccggggtgt tcccggcggg cacgtcggcg gcgctcgccc ggaggttcgg
     5041 gccggggctg tcccggggga ggtggaccgt tgcctgaccg gagtccggcg gccgagccgc
     5101 tgatcctcga cgtcggcagc gcgggccagc tcgcggagct ggccggcgac ctggtcgacc
     5161 tggccgggcc cggcggcgcg accggcccct gggtgctcac ctgggcccac ggcgccgggg
     5221 agccgggcgg ggagccgggc gaggggcaga accgggggcc gaacgggggc acgggcgggg
     5281 gcccgggcgg gacggtggcc cggccgccgg gcgccacggt cgtgcgccac ggcgggctgg
     5341 aggtggtcac ggtgccccgt ccgccacgcg acctcggcgg tttcctcgac gcgtgctgcc
     5401 gcaccggccc ggtctcgggc cacccggacg tcacccgcac gatcctcatc cttgccgacc
     5461 ccacggaccg ggaccggtcc gcttcccctc cggaggcacc tcatgacgca ccccgcgacg
     5521 gggcccgcga cgggcggccg tgaccgctat ctcttcatca ggatcctgga ggcgtgcaac
     5581 gccgactgct tcatgtgcga gttcgccctc tcccgcgaca cctaccgctt caccctcgac
     5641 gacttccgcg aactgctgcc gcaggcacag gagtcgggcg tgcgatacgt ccggttcacc
     5701 ggcggcgagc cgctgatgca cggcgaggtg ctcgacctga tccgcgaggg caccgccgcc
     5761 ggcatgcgga tgtcgctcat caccaacggc ttccggctgc cgcagatggt cgacaagctg
     5821 gcggaggcgg ggctggcgca ggtcatcgtc agcctcgacg gctcctccgg tgagacgcac
     5881 gacgtctacc ggcgcacccc cgggatgttc gaccgcgggc tggacggact cgtacgcgcc
     5941 tcccgggcgg gcatgctcac ccgcgtcaac acggtcgtcg ggccgcacaa cttcgcgcag
     6001 atgccggagc tgcagcgggt cctgaccgag gcccgcgtgg agcagtggga gatgtccgcg
     6061 ctcaagctgg aacggcacat cgcctacccc ccggccgagg aggtgctcca cgcctgcgaa
     6121 cccgtcttcc tggccgaccc gaagcggtgg ctggtgcccc tgggcaagcg cttctacggg
     6181 gagaccgccg aggaacggga ggcgttcttc gagcgcggca cgaccccgag cgcgtcacgg
     6241 ccgctgtgcc atgtgaccga cgacgtgatg tacctggacc ccaagctggg ccgcaccttc
     6301 gcctgcagct gtctgcccca ccgggacggc ccgggcgccg acatgcgcga cgagcggggc
     6361 cgcgtcttcc tcaacagccc ttcgttccgc gcgcacgccg aggagttcaa gcagcagggg
     6421 cccgtgatct gcagcggctg ctcgaccacg gcggccggct acagcgacga cgtggcccgg
     6481 ctcggctcgg tgcccgcctg gcactactga ccggggcgcc acgccctttg ctcgcacgcc
     6541 ccgtccgtac acccgtacgc ctcctccacc gcccgcacgt catcctccgc ccaggaagcc
     6601 gaacatgatc ctgcgtaccg accacgtgga cgcgtatctg tccgccgtgt ccgccatcct
     6661 cgacgagccc ggccgcgccg gggccggcgt ccccgtgctg tgccggccgg gctctccgct
     6721 ggacgtgctg gtgacccgct ggtccgccct gctgggccac gccgggccgc gtgcccgctc
     6781 ggaccggccg ggccgggccg tcgtcgcggt cggcgacgac cccgtcgtct ccgcggcggc
     6841 acggctgctc gccgtgctca cgggacggac cgcgctggcc gtcgccgacg tcaaggagct
     6901 gcccgccctg tgggagcggc acgacctcgt ctccaccgcg ctggtgggca tcggcaccgg
     6961 gttcgacgtc ccgggcgtcg agcccagcgc cttctggcgg ctcgacgcga ccgacgcgac
     7021 cctcggcatc ctgaccggcc gggaccggga gtccctgacc tggttcgtcg ccaagagtct
     7081 gctcacctcc accgtccccg gcgacgcgca gacgctgctg ctgccggacc gcaagccgcg
     7141 cgaggacacg gcgtcggcgg gcgtgggtgc cgggggcgtc gaggtgctgt acggggccgc
     7201 cgccgaggag gcgctgcccg cgctcgccga ggacgagcgg gtacgggcgc tgatcgccgt
     7261 ggaggcccac ggcagggccg accacctggg ggtgcgggac ggcatcatct gcggcgaccg
     7321 gctggcccat ctgggccggt ccagcgagcc ggagggcatc gggcgggtgc cgcagtgcgc
     7381 gttcgggcac ggctgcttca agcccggcgc ccgggtggcg atctcccgta tgccggcgca
     7441 gtcgctgttc ctgcacagct gcaccagttc gcacaccgag gcggacatgt acgagaagtc
     7501 gttcctgctg ggcctggccg ccctggaagg gcccgcccgg cacgtgctgg gcaccgtccg
     7561 cccgatgcac gacgggggcc acgaggtcgg actcgtctcg gcgttgacgg cggcgggcgc
     7621 ctccgccggc gaggtgaccc ggctgctgaa cgcctcctac caccagcacc gcggcgagcc
     7681 cgcgccctat ctgctgctcg gcgacccgga gctgccgttc gcggacgggc cggtgggcgg
     7741 gccggacgcg ggcccggccg tggagctgga cgcctccgcc ggcgcgctgc cgctcggcgg
     7801 ccggcgcacg gcggtcctgg gcagcggccc cggcgtgctg gtcgtgggcg acgcgaccgg
     7861 ggacgaggac ggggacggcc cggggcttcc cgcgggcgtg ggcgcgctga ccgtccggcg
     7921 cggcgaccgt acggacgtcg tggcgtggag caccgagggc ccgctccccg aaggggcgct
     7981 tccgttggtc cgccgggagg gcggggcggt ggccgcggac ggcggtgccg aggagctcca
     8041 cgcccgctgg gaccacgtcg accacggcat cgcgtcgggc ggcgcgctcg gcctgctgcc
     8101 caaggacctc acgggcaggc tccaggagct gcgggacctc gccgcagccg tcggcaccgc
     8161 cgaccgggac gcccgcttct tccccggccg cctgggcgcg gtccggcgcg cagcggcccg
     8221 gctcgaccag cggatccgcg acgccgaccg ggcactgatg cacgcgctgc tcggccgcaa
     8281 cggcaagccg ttcgacgccg acgacaggct ggagagcgcc ttcgtgccgc tggagtccca
     8341 gtacggccgc caggtgtgct ggtgcggccg ggacgcggtc gtcagccggc tgcggccccg
     8401 gctgggcgcc cgggaagtgc gccggaagta caactgcatg cagtgcgggg actacgccca
     8461 ggtcgcggtg gacggcgtcg acgtgcgctg ggaggccccg gagttcgtgg cctcgggagg
     8521 cgagctggag cactccttcc ggatcgccaa cccccttccc cacccggtca ccggggtgct
     8581 cgcgctgagc gtgtccccct ggtacggcgg cgacgtgtcc ttccgccccg gcatcgcgac
     8641 cttctcggtg gcgccgggcg gcacgtgccg ggtgggcgtc acgatgcgcg ccgccgggct
     8701 gaagccccac cgctacacgg tcgacgcgac ggtggtcagc catctgcgca tcaacgccta
     8761 tcgcaagttc gtgcaggtcc gcccggcggg acccgtcggc ccgagcgacg aggacggtgc
     8821 gctgtgacag cacctacgac cggaccgacc accggaccca cgaccgggcc cacggccggg
     8881 cccacgaccg ggcccacggc cgggcccacg gccgggccca cggccggatc ggcggtcgcc
     8941 gaggaggccg tggcggagtg ggccgcggcc tggctggagc aggtgcacgg ggtgcgctac
     9001 gggcccgacg acgcgctctt cggctcgctc gactcgctcg cgctgaccga gctcctggtg
     9061 gcctgcgagg cccatttcgg gctgcgcatc gacgaggggt tcggctggca ggcgctcgcc
     9121 tcggtccgca gcctcgccgc ccatgtggcc acgggggtcc gcccgcccag cgaccgcgtc
     9181 tggttccggt cgggccccgg cgcgaccggg gacgcggacc tggaccgtac ggccgtcgtc
     9241 cgggtggcgc tggggctgcc gccgggcgcg gccgtggccc ggctctcccc gagggagctg
     9301 gcgctgggca tcggcgccgc cgcagcgcct tccgagaagc cggccacgac cctgccgccc
     9361 gagcgcgaac ggctttccct cgctcgggag tcgagcaccc ggcccggctc gctgctggcc
     9421 gtcggcgcca cggccgcgcg gatccgggcg ttcgccgggc gcctcgacgc cgcgctcgcg
     9481 gcggtggggg ccacgcccgt ctggtacccg atcacgaccg acagccccgt cggcgccgac
     9541 cacgtccagg gcatcccctc cgagctgacg gcgggccgcc tcgggcacgc gggctgtctg
     9601 cagctgctcg ccgaactgcc cgcggaacgc gacgtcgtgt actcgggcat cgcctacgcc
     9661 ttccgggacg agcccggccg ccgctgggaa cccgccggcc ggctggaggc ctaccgggtc
     9721 cacgagacgg tcgtgcacgg caccgaggag ttccgcacgg cgatgtggcg acggctgtac
     9781 gagctggtgg accgggagct gtcggccctc ggcccgggcg gctggcagga ggggcgggac
     9841 ggcttcaccc cccggcatgg accgcaagct cgaatggctg ctggaactcg acgctgggca
     9901 cggtgagcgt ggggggcacg gccatccggg tggacggatc gcggtggcct cgctcaacga
     9961 ccacggcggg ctcttcgcgg cggcgccgga cggctccggc acgccggacg gcggcccgcc
    10021 gggctccttc tgtctgggca tcggcgtcga ccggctcgcc tcgctggggg tgatctgatg
    10081 gacgccgcgc ccggcaccgc ccgtacggcc gcgggcacgt ccgtaccgcc cgtactcccc
    10141 gtcgatgccg aacgtcccgc cgcccggcgc accctggcca tggaggaggg cacaccccgg
    10201 cagtgggagg gcctagggct gcacggtgtt ccggaggccg tggaggcggc gctgggcccg
    10261 gccgccgagc tggtcgtcgc cgcgcggggc ggcggccggt ccccgctgcc cggcctcgtc
    10321 ttcgcccagc cctgcctcgg ccgctccgcc ggcgtggccc gggacctgcc cgtctccgtg
    10381 gtgtgggaga cgggcgtggc cctcgcgatc gcccgggcgc tggaccggcc cgcggtgatc
    10441 gggctgtgcg tgtacgagga gatcctccag cagccgcacc gggacgccga gttcaccgcg
    10501 ctgggcgcgg ccgtcgcgcg gaccgtcgag gcgctgggcc ggctgctggg cgtggcggtc
    10561 accgcccgcg tcgagaccgc cgcgccccgc gccgcggagg tgccggcgcg acggctctac
    10621 ggtctgtaca cgccgttctc cgaatccacc tatccgaggg gtttccccaa cgaggcggag
    10681 gtgctgcgcg ccttctccgc gtactgcggg cgctacgagg acgccgcccg gcgggaggcg
    10741 tccctgtggg tgacggaagg cgtgcacctg gccaaggcgg cgctcctcgg cctcggcccc
    10801 ggcgtgccct tcctggccac caccccgctg cccgaccctg cgcaccccgg ccggcttctc
    10861 caggacgccc cggccgccac ccgggtcacc ctggaacgcc gctcggcgct gcctgccgac
    10921 tggtggccgg agcaggcgct ggaacgcgcg ctcgggaccg gtctgcggcg gctgaccgag
    10981 gacttccacg cgctgatcga agacttccac gacccggcgg gagaccgatg agaacgcccc
    11041 ggaccggagc cgtcctcggc gggcgcggcc ccgccctgcc cttcgtcgcc tatatggcgc
    11101 tctccaacgc ccagttcacc cggggcgtgt tcgtcctctt cctgctgcgc gggaacatca
    11161 gcctggccga agtcggactg ctggagagcc tgttccacct cacccgggtg ctctgcgagg
    11221 tgcccgccgg cagcgtcgcc gaccgctggg gccgccgtcg tacgatccag gcgggcctga
    11281 tcctctcggc ggcggcgatg ccggcgttcc tgctcggcgg gatgttctgg tacgcgctgg
    11341 cgttcgtgtt ccagggcgcg ggctgggccg cccagcgcgg cgccgacacc gcgctgctgt
    11401 acgagctgct ggaacggacc ggcgggaccg atcgctacgc ccgcatcctg gggcgctccc
    11461 acgcggcctc gtacgggacg ctcgccctca ccaccgcgct cggcgcgatg ctctaccagc
    11521 ggcacgtcag cctgccgttc tggcttcagg cggccgtcac cctgctggcc gtcggggcga
    11581 tcggcgtgct gccggagagc tcggggacgg cggcgtcggg ggcggggtct tcggggtcgg
    11641 ggtcctcggg ggagccggcc gaacggccca tgggtgtctg gcggctggcc cgcgcggggg
    11701 cccggctggt ggtcggccac cccgtgctga ggctcttcgt cgccttcgtc gccctggtcg
    11761 aggccgggac gacggtggtg agcatcttct cccagagctt cttccggacg ctcggatacg
    11821 gcaccgccac caccgggctg atcctcgccc tggtcacggc cttcagcgcg gcggccgcgc
    11881 tgcagtccca ccgcctcgtc gaacgcggtc cggtccgggt gctgatggcc gcttcgagcc
    11941 tgtacctcgt ggggctggcc gggatggcct cgctgcagcc gcagctggcc gtcgtgggct
    12001 actacctcgt cttcctcaac cttgacctgc tcgccccggt gctgagcgcc ttcttccacc
    12061 gctctgtgga cgaggaggtg cgagcgaccg ccggttcgta cctcaacctg tcgaccagcg
    12121 tgctcacctt cgccgccttc ccgctctccg gctcgctgat cgacgccggc ggctaccgcc
    12181 cgctgctgat catcaccgcc ctggtcagcc tgccgctcct ggtcttcctc gtcggcgcgg
    12241 cccggcgggt cctctcaccg ccggaagagg gcgattccgg ggaggacgcc ggggagcggg
    12301 ccgggcccaa ggggcccggt gcggcggcac ccgacaccac cacgacggga gtgtgagaac
    12361 accatgacca ccagggctga ctccccgtct cccgggtccg gcgggcctgt cggacccggc
    12421 gggtccggcg gcgacgacgg acggccggtg atcgcgctgc gcttcgcccc ggccgacgtc
    12481 gaagcggcgg ccgcggcgga gtacgtcgcc gcgcacctcg gcggtttccg gtgcctgccg
    12541 gagtgtcccc aggagggcga ttccggcccg ggccggaatc cacccgccgc cgtgatcgtc
    12601 ttcgggcggt ccggtgccgc cggaggggcc ggtcccgcgg gcgtgcccac cgtcctggtc
    12661 gagggcgcgg aaccggtgcc cggcacggac gcggacgtcg tctgccggca ggcgcccggc
    12721 tggctcaccg ccggggaacc gcccgccccg cccgccgtac gccccggcgg cggccggatc
    12781 cgcaccgtgg acgtggccgc cgtcgcgccc ttccgtcagg tgcggtcggg cgggggtggc
    12841 gggcgggctg ccctcctgct cggcggggcc ggtgggcccg acgggtccgg tgcgtccgcc
    12901 gggggcgagg ctcttcccgg cgccctcgcc cggttcatcg ccgggcatcc ggccgccgcc
    12961 ggtgacgcgt gggccgtgct caccgatctc accggggagc ccctgcggga gctgctcggc
    13021 ctgctgcccc cgaccgcccg cacggtgggt gcggcggact gggcccaggt cctgcgccgc
    13081 gcggactcgt tggtggcgac ccccaccctg ctggccgccg cccatgcccg taccgcccgg
    13141 atccccctgc acgtactgga cccggcggga ccggcccagc ggcgcgtcca ccgggcgctg
    13201 gccgcgatcg ccggcgctcc cggggagccg ggcggcctcc cggtggtcgg gcccgacgac
    13261 tggccgcgtg acgacggccg cgccggagcc ctgggcgggg ccgcgcagat cgcccggcag
    13321 gtgcggcagt tgtgcctcgc gccggcctga accgtccggc gggtcctgtc acgtcccttg
    13381 agacgtccct ccggggcgtc ccccacgcaa aggtatggat ggcatgtccg acactctcgc
    13441 gcacaaccgt cccctcgacc tgacccagca cgagatagcg gccctgcgct ccgagcacaa
    13501 tctcgcggac gcgcacacgc accagtacca gtcgccggcc cagcagctca tcgtggactc
    13561 cctgcccgcc ctctggcacg aggcggagaa gggccggcag gccgatttcg aacagcggtt
    13621 catcgaggcg ttcttccggc tgcacggcca gcccacggcc atcggcctgg accgcacgct
    13681 gctcacctac gccgcctcca tctccacgat gatcgccggg atgttcctca agcgccgcga
    13741 cgcgcgggtg acgctggtcg agccctgctt cgacaacctc cccgacctgc tcgtcaatct
    13801 gggcgttccg ctcaccgccc tccccgagga tgccctgcgc gaccccgcgc gcatccaccg
    13861 cgaactgtca cggctggtga ccaccgaggc gctttttctc gtcgacccca acaacccgac
    13921 tggccatagc ctgttcgccg acggcatgcg cggcttcgag gaggtcgtac ggttctgccg
    13981 cgagcgcggc acggtcctcg tcctcgacct gtgcttcgcg gccttcgccc tcggcagtgg
    14041 cggacccggc cgtcacgacg tctacgagct gctggagaac tccggcgtca cctacatcgc
    14101 catggaggac accggcaaga cctggcccgt ccaggacgcc aaatgcgccc tgctcaccac
    14161 cagcgccgac atctaccccg ccgtgtacaa cctccacacc agcgtcctgc tgaacgtctc
    14221 gcccttcatc ctgaacaccc tcacccgcta catcgaggat tcccggcggg acggcttcgc
    14281 ctccgtgacc gacgtcctcg aacgcaatcg caagtccctg cgggcggcca ccgagggcac
    14341 ggtgctccgc gcccacgagc ccgacgtccc ggtcagcgtc gcctggttca ccatcgacga
    14401 ccgcggcccg gacgccacgc agctgcagcg cgacctctcc ggccacggca tccacgtcct
    14461 gcccggtacg tacttctact ggaacgagcc gagccgcggc gagcgctacg tccgggtggc
    14521 gctggcgcgt gatcccgggg agttcgacgc ctccatggcc cggctgcgga cgcttctcgc
    14581 ccgctatgcg tgagcccggc ctcatcgctc cgctggtcac cccgctgacc cccgacggcg
    14641 cggtctcgga agcgtgcgta cgggcgcagg tcgcgcgcgt ccgcccgtac gtccgcgccc
    14701 tgatgcccgg catcagctgc ggggaggggt ggctcctgga ccgtccgcgg tgggagcggc
    14761 tggccgccgc cgtcctggac tgccgcgacg gcctgcccgt ccacctcggt gtccaggcgg
    14821 cggacacggc ggaggtgatc cggcgcgccc gctgggccgt acggcacggg gccgacgccg
    14881 tcacggtcgg ccccccgcac ggcgcgggcg cccggcagcg ggcggtccac gagcacttcg
    14941 cgcgggtctg cgcggcggtc gacacccccg tctgcgtcta ccacgagagc gtcgtcagcg
    15001 gcacgcgcat gacgcccgcc acgctgaccg ccgtctgccg gctcgacggc gtccgcgccg
    15061 tgaaggagtc gggccgcgag ccgtccgtca ccaacgacct catcgccgcg gttcccgacg
    15121 tggccgtcca ccagggctgg gaggacctct tccacgccac gcccggggcc gccgggctga
    15181 tcgggcccct tgtcctcatc gacccggcgc tgtgcgcgga gctcgtcgcc ggggtgggtg
    15241 gggtgcaggg ggtggtgacg gaccgctgtc gtgagctggg gcttttccga cctgattatg
    15301 tggcccgcac caagcgggag ttgtgccggc tgggtgtcct ggcccatgcc gtgacgctgt
    15361 gaccccccac cgtacggaaa tgggagtgac catgaatcct tcgaagacct ttctcgttgt
    15421 cgggccgctg cgtgccgaca ccggctggca gtagagggca cggccgatca tttctgagtt
    15481 ctcgtggagc gaggcggtgc ggctggccgg cgtcgcggcg gaggcgctcg gggcgggaga
    15541 tctggcgggc gccgtcgggg cgcttgaccg ggtggccgcg ctgatccggc tggcggggga
    15601 gtcggggggc gggggtgctg cggccggggt gcggggcttt cgggcgagtg cggcgctgat
    15661 ctgggacgcc ttcgcggcgg ctgcgtccgg gccgtgcgac gcgctgcgga tcgcggaggt
    15721 ctgccgggcg ctgcgggggc tggacgaggc ggtggcctcc tgggaggaga cctgttaccg
    15781 gttcttcccg gcgctgggtg gggaggaggg ggcgggctgt gcggggccta cggcttggtg
    15841 agcgtcgggg gcggggccgt gggtcggggg cggggtgggg tggacgggcc cttacggggc
    15901 tgatctcttc gcggtgcctg ccttcagggg agggtgcccc gtatttggct tcagcggcga
    15961 agagctcttt acgcccctac cagggcccgt tcaccccacc ccgccccctc gcgtcaccac
    16021 ctcgcgggct gcggttccgg gtgggcgggt gggcgaaacc ccgcgccgcc aggcgcggga
    16081 aaccccacgg cgggtcagcc ggagagtcca cggaaccccc gcaggggagg cggtccgccg
    16141 gaaaggcgga ggaggccgcg gtccgccgcc agaacgcccg cctggaagcg actctccgcc
    16201 cccaactccg ccatcatctc cgcgatgtgc cgccgacacg tccgcgtgga catgttcatc
    16261 cgcttggcga tgacctcgtc cttcgccccg gccgccatca gccgcaagat gcccgcgcgg
    16321 atctcgtcgg cggcggggcc gtagcccacg tgcgtgtaga cgaagggttt cgccaggcgc
    16381 cagacctgtt cgatggtccg gtagaggtag tccacgaccg ccgggtggcg gatgacgacc
    16441 gcgccggggc cgtcggagcg gcggtcggcc aggaaggcca gcgattggtc gaagatgacg
    16501 acgcgatcga gcaccccggt cgtggtcctg atctgggtgc cggcctcgtg catcagcgag
    16561 aagtgctgct ggaccgccgg gctcgacagg acggtgtgcg gatacacggt ccgtatggcg
    16621 atgccccggg tcagcaggga caggtcccgg gggcggctgt cggcgagggt gctctccagc
    16681 agggcttcgg gctgggcggt gagcacctcg tgccggcagt cgcgcgcggc agcgctcaac
    16741 agcccgcgga tcgtgctgat gtcggtgagg gactcgatct gcggcgcctt ccgggcgcgc
    16801 ccctcgttga ccgcgtcgta cgcgtcctgg agcgaggcca tggcgctgcg cagccgctcg
    16861 tcctccaggc gctgccgctg gatctcgccc tcgcggaccg cgctcagcgc ggcggccgcc
    16921 gactgcgggc tgatcgcggc cagcagtcgc ccgcggtccg tgtgctggat caggcgcagc
    16981 gcgacgagcg cgtcgatcgc ctccgtgagt tcgtggtccc cgtcggcgtc cgttccctcg
    17041 ccgctgtgtt ccggggggcc gggcgtgcgc agggccgtac ggggcaggga gccgccggcc
    17101 cgcaggatct ccaggtacac ggcgcgggcc cggccggtca gccgggcctc cgtcaggggg
    17161 cacacgccgg tcatcggccg gcctgcccgg cgccctccac cacggcgggc tcccagaccg
    17221 gggcggtcac ctccttgacc gcgccgtccc cccggaagtg caggaagcgg tcgaaggacc
    17281 gggtgaacca gcggtcgtgg gtgacggcca gtacggtgcc gcggaagccc gcgaggccct
    17341 gctccagcgc ttcggcgctc gcgaggtcca ggttgtccgt cggctcgtcg agcagcagca
    17401 aggtcgcccc ggagagctcc aggaggagga tgaggaagcg ggcctgttgg cctccggaca
    17461 gcgtctcgaa gcgctggccg ccctggccgg ccagttcgta gcggccgagg gcggccatcg
    17521 cctcgtccct gggcaggctg tcgcgccgga cgtcgccctt ccagaggatg tcctcgaggg
    17581 tgcggcccac gagttcgggc cggtcgtggg tctgggagaa gtgcccgggc accacccggg
    17641 cgcccagtcg ggcgctgccg gtgtgcgcca cgggctccag cggggtgagc gacggcagct
    17701 cggggtcgct gcccccgcgg cccagcagcc gcaggaagtg ggacttgccg gtgccgttcg
    17761 cccccaggac ggcgatgcgg tcgccgtacc aggcctcgaa gccgaaggga tccgtcagcc
    17821 cgtccagtcc cagccgctcg cagacgacgg cccgtttgcc ggtgcggtcg cccgtcagcc
    17881 gcatccggat gttctgctcg cgcggccggg gcggcggggg cggctgcgcc tcgaacttcg
    17941 ccagccgggt gcgggcggcc tgcagccggc tggccatggc gtcgttgtgc gaggccttga
    18001 cctggtagtg gcggacgagc tccttgagct tggcgtgctc ctcgtcccag cgacggcgct
    18061 cctcctcgaa gcgctcgtag cgggagacgc gggcgtcgtg ccaggaggcg aacgagcccg
    18121 ggtgcatcca ggcggagccg ccctcgacgg tgaccacgcg cgaggcggtg ttggccagca
    18181 gctcgcggtc gtgcgagacg tagagcaccg tcttcgggga ctcggcgagg cgggcctcca
    18241 gccggcgctt gccggggacg tcgaggaagt tgtcgggctc gtcgaggagc aggacctcgt
    18301 ccggcccggc gagcaggagc gagagggcga acctcttctg ctcgccgccc gacagggtgc
    18361 gcaccggacg cgaacgggcc tcgtcccagg gtgtgccgag gatgtcggtg acgacggtgt
    18421 cgaagacgac ctcctgttcg tatcccccgg cgtcgcccca ggccaccagg gcctcggcgt
    18481 agcgcagttg tgccttctcg ccggcgccgg gtacggccat cgcggtctcc gcccgcgcca
    18541 gtgcctcgcc ggcgccgcgg agcccggcgg gggagaggga gagggccagc ccggcgagcg
    18601 tggtctcgtc gctgaccatc ccgatgaact gccgcatcac gccgagcccg cccgagcggg
    18661 cgacggcccc gcgcgtcacg gggagatcgc ccgcgatcat gcgcaacaac gtggtcttgc
    18721 cggcgccgtt cggtccgacg agggcgacct tcatgccctc gcccactctg aaggagacgt
    18781 cttcgaagag aacgcgccca tctggcagta catgacggag acttgtcaca tcgacatatc
    18841 ccatgtgcgg aatcttgcaa catgcacggg atctctgtca cgcgactttg cggaaccagc
    18901 cactctggta tgtatccctg ggtaagcggc ttgattcgca tgtccgttcg caaggggtgg
    18961 atgtcctttc cggctcttga tctcgtgtgc gccaggcggt aattgggccc gttcgggggg
    19021 cccgtttccc gtagggtgga cgcgtgatcg aggacggcgg cagcgcgcgg ggaagtgtca
    19081 ccacggtgcg gcgtgtgggg gacaccgtcc gccgtccgcg cggccgctgg accgccaacg
    19141 tgcacgccct gctgcgccat ctggcggacg ccgggttcct ccgcgcgccc cgggcgctgg
    19201 gcgtcgacga ggacgggagc gagatcctgt ccttcctcga cggcgaggtc gcgatgcgtc
    19261 cctggccggc cgcgttgcgg gagcggtccg gtgttgtcga gctggccgtg tggctgcgcg
    19321 aataccacga tgttgtacgg gacttccgtc cgccgtgccc tgatgagtgg ttcgtgcccg
    19381 gtgtctcctg gcgtcccggg cggctcgtcc gccacggtga cctgggaccc tggaactccg
    19441 tctggcgtgg ctcccggctc gtgggcttca tcgactggga cttcgccgag cccggcgatc
    19501 ccctcgacga cctggcccag ctcgcctggt actgcgtccc tctgggcggg cgtgcgactg
    19561 gggcgggcgg tgaggagagc cgggtgcggg tccgggagcg cctcgcggcc gtgtgcacgg
    19621 cctacggggc cgagcccgtg tccgtcctgg acgccctggc cgggctgcag gagcgcgagg
    19681 cccgccgcat caccgacctg ggcggccggg gcctcgagcc gtggacgtcc ttcctcgccc
    19741 ggggcgacgc gacggcgatc gaggaggagc gcgcttggct gctgacccac cgggaggggt
    19801 tgctggtggg atga
//
