LOCUS       BGC0000886             15080 bp    DNA     linear   BCT 11-MAY-2010
DEFINITION  Streptomyces tsukubaensis strain NRLL18488 allylmalonyl-CoA
            biosynthesis gene cluster, complete sequence; and FkbG (fkbG) gene,
            complete cds.
ACCESSION   BGC0000886
VERSION     BGC0000886
KEYWORDS    .
SOURCE      Streptomyces tsukubensis
  ORGANISM  Streptomyces tsukubensis
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 20:56:57
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15080
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..15080
                     /db_xref="taxon:83656"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces tsukubensis"
                     /strain="NRLL18488"
     subregion       1..15080
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="Other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..15080
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            2775..4070
                     /gene="allA"
     CDS             2775..4070
                     /NRPS_PKS="Domain: PKS_AT (7-299). E-value: 2.1e-59. Score:
                     193.1. Matches aSDomain: nrpspksdomains_allA_PKS_AT.1"
                     /NRPS_PKS="Domain: PP-binding (348-416). E-value: 2.1e-12.
                     Score: 39.3. Matches aSDomain:
                     nrpspksdomains_allA_PP-binding.1"
                     /codon_start=1
                     /gene="allA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 172.5; E-value: 2.7e-52)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative acyltransferase and ACP; component of PKS"
                     /product="AllA"
                     /protein_id="ADG39431.1"
                     /sec_met_domain="PP-binding (E-value: 3.8e-13, bitscore:
                     39.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 3.9e-60, bitscore: 193.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSGVAFLFPGQGSYVPGVFAGLGADAGRVATLVAEIDAAVEEFR
                     LKPVRPLLFSPDAPALAELLESDHERLDVAILATSIALAELLESRHGMSPDHVAGHSLG
                     EFGALAVAGVFTPGDAARAVCERHATLRKAPPPTGGMLAVKADAARAGELIAAARAGTS
                     AVSALNSPSQTVISGAEADLVKVQQLAREEGIRTSRLHVPGPFHVPQLADASALYATTM
                     RTIRISAPRERFFYSHGLGRFLTAQDDVVDLMVNDMTRPVRFHDSVRALNAEGVTTYVE
                     CGALDVLTRIVSGSLPRAVTLAPLREATTTPDLSARLRPAGTPAVNGVAAPAGPAPAAE
                     VDPEVLAGVRAVCAEVLEYPLEVITDDADFQADLGVDSLAMTELQAHALQRFGLKETLQ
                     DADTGTYGTVSGLAAYITGLLSEGTGSVSGRR"
     misc_feature    2775..14123
                     /note="allylmalonyl-CoA biosynthesis gene cluster"
     aSDomain        2796..3671
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_allA_PKS_AT.1"
                     /evalue="2.10E-59"
                     /label="allA_PKS_AT.1"
                     /locus_tag="allA"
                     /protein_end="299"
                     /protein_start="7"
                     /score="193.1"
                     /tool="antismash"
                     /translation="LFPGQGSYVPGVFAGLGADAGRVATLVAEIDAAVEEFRLKPVRPL
                     LFSPDAPALAELLESDHERLDVAILATSIALAELLESRHGMSPDHVAGHSLGEFGALAV
                     AGVFTPGDAARAVCERHATLRKAPPPTGGMLAVKADAARAGELIAAARAGTSAVSALNS
                     PSQTVISGAEADLVKVQQLAREEGIRTSRLHVPGPFHVPQLADASALYATTMRTIRISA
                     PRERFFYSHGLGRFLTAQDDVVDLMVNDMTRPVRFHDSVRALNAEGVTTYVECGALDVL
                     TRIVSGSLPRA"
     aSModule        2796..4022
                     /complete
                     /domains="nrpspksdomains_allA_PKS_AT.1"
                     /domains="nrpspksdomains_allA_PP-binding.1"
                     /locus_tags="allA"
                     /starter_module
                     /tool="antismash"
                     /type="pks"
     CDS_motif       3048..3155
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_allA_0001"
                     /evalue="2.60E-12"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="allA"
                     /protein_end="127"
                     /protein_start="91"
                     /score="38.7"
                     /tool="antismash"
                     /translation="GMSPDHVAGHSLGEFGALAVAGVFTPGDAARAVCER"
     CDS_motif       3273..3308
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_allA_0002"
                     /evalue="1.00E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="allA"
                     /protein_end="178"
                     /protein_start="166"
                     /score="12.4"
                     /tool="antismash"
                     /translation="ALNSPSQTVISG"
     aSDomain        3819..4022
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_allA_PP-binding.1"
                     /evalue="2.10E-12"
                     /label="allA_PP-binding.1"
                     /locus_tag="allA"
                     /protein_end="416"
                     /protein_start="348"
                     /score="39.3"
                     /tool="antismash"
                     /translation="VRAVCAEVLEYPLEVITDDADFQADLGVDSLAMTELQAHALQRFG
                     LKETLQDADTGTYGTVSGLAAYI"
     gene            4078..6468
                     /gene="allK"
     CDS             4078..6468
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (15-461). E-value:
                     1.3e-70. Score: 230.2. Matches aSDomain:
                     nrpspksdomains_allK_PKS_KS.1"
                     /codon_start=1
                     /gene="allK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_KS"
                     /gene_kind="biosynthetic-additional"
                     /note="PKS; putative ketoacyl synthetase"
                     /product="AllK"
                     /protein_id="ADG39432.1"
                     /sec_met_domain="PKS_KS (E-value: 2.4e-71, bitscore: 230.2,
                     seeds: 2284, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISRAPDGEGPHDDRVAVVGMGVAVPGACDPEELWKLLCGDRPVF
                     DEPSDRFRLDSFWSADPAAEDRGYVRTSGFLHDFRPHPALAAEIAAGTLSAAAQNPVWL
                     RHCLLQARDTVTARSTDRYAYHVGTSALVGQRTDEAVLAECVPRAVAERLHRDEPARMA
                     EAEARLRALLRSHHGYGAEEPRDTLPDRVVRAAAAGLLPDDCEFSVVDAACSSSLYAIG
                     LGVASLLAGACDIAYCGGVSGVTPRYNVTFSKLHGLSPSGDVRAFDDDADGTLFSDGAG
                     VVALKRLDRAVEDGDPVFGVLVGFGGSSDGRGTAIYAPNPVGQRRCLDRARQASGLTAD
                     DVDWVIAHGTGTAVGDAVELRTLAAATDPGSVWCGSNKSLLGHTGWSSGVVSVVQALTA
                     LRQGTIPAQRRFTGPGLTAQTGDRVRIPSADVPWHAGGRRSRTAGVSAFGFGGTNAHLL
                     ITDREPVRTGPRPARTGPDPVVVLAWTAHLPGDPGPEATERLLREGRIPGPRTFGPRYP
                     APPFPDVRLPPPTVRSTDAGQLMALRVAGLFAAEHGELWAPVRATTGVFAAATGPPPSS
                     MDHLVRCHAADVHRILDEPDRTAFTEWLADLRATTPATTKDTLPGLLPNIIPARIANRY
                     DLGGPTMLVDTGTTSGLTAVHTAVRQLAAGAVDMALVLGVSATGRPEFARFMGVAAERI
                     AEGAFLLALSRESVALAHGLTPLVRLRTDWTGSPQASADAVPGGPGAAEDTFLGADGVL
                     AVIRALHSTASGVTVGPADGEPGPVITLSPADGSPLRQTRTSR"
     aSDomain        4123..5460
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_allK_PKS_KS.1"
                     /domain_subtype="Modular-KS"
                     /evalue="1.30E-70"
                     /label="allK_PKS_KS.1"
                     /locus_tag="allK"
                     /protein_end="461"
                     /protein_start="15"
                     /score="230.2"
                     /tool="antismash"
                     /translation="VAVVGMGVAVPGACDPEELWKLLCGDRPVFDEPSDRFRLDSFWSA
                     DPAAEDRGYVRTSGFLHDFRPHPALAAEIAAGTLSAAAQNPVWLRHCLLQARDTVTARS
                     TDRYAYHVGTSALVGQRTDEAVLAECVPRAVAERLHRDEPARMAEAEARLRALLRSHHG
                     YGAEEPRDTLPDRVVRAAAAGLLPDDCEFSVVDAACSSSLYAIGLGVASLLAGACDIAY
                     CGGVSGVTPRYNVTFSKLHGLSPSGDVRAFDDDADGTLFSDGAGVVALKRLDRAVEDGD
                     PVFGVLVGFGGSSDGRGTAIYAPNPVGQRRCLDRARQASGLTADDVDWVIAHGTGTAVG
                     DAVELRTLAAATDPGSVWCGSNKSLLGHTGWSSGVVSVVQALTALRQGTIPAQRRFTGP
                     GLTAQTGDRVRIPSADVPWHAGGRRSRTAGVSAFGFGGTNAHLLITD"
     CDS_motif       4702..4737
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_allK_0001"
                     /evalue="1.10E-03"
                     /label="PKSI-KS_m3"
                     /locus_tag="allK"
                     /protein_end="220"
                     /protein_start="208"
                     /score="11.6"
                     /tool="antismash"
                     /translation="VVDAACSSSLYA"
     CDS_motif       5113..5154
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_allK_0002"
                     /evalue="6.00E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="allK"
                     /protein_end="359"
                     /protein_start="345"
                     /score="9.5"
                     /tool="antismash"
                     /translation="IAHGTGTAVGDAVE"
     CDS_motif       5992..6039
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_allK_0003"
                     /evalue="8.40E-02"
                     /label="PKSI-KS_m3"
                     /locus_tag="allK"
                     /protein_end="654"
                     /protein_start="638"
                     /score="6.1"
                     /tool="antismash"
                     /translation="GPTMLVDTGTTSGLTA"
     gene            6465..7802
                     /gene="allR"
     CDS             6465..7802
                     /NRPS_PKS="Domain: PKS_ER (50-410). E-value: 1.2e-23.
                     Score: 75.5. Matches aSDomain:
                     nrpspksdomains_allR_PKS_ER.1"
                     /codon_start=1
                     /gene="allR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 317.7; E-value: 1.4e-96)"
                     /gene_kind="biosynthetic-additional"
                     /note="enoyl-CoA reductase; similar to corotonyl-CoA
                     reductase"
                     /product="AllR"
                     /protein_id="ADG39433.1"
                     /sec_met_domain="ADH_N (E-value: 9.1e-10, bitscore: 27.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.5e-27, bitscore:
                     85.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHVRDAAATDDPQAIAACEVPAGYRAAVVLAADHQALAGSPVED
                     RDPRKTVQVQEVPTPEPDHGEVLIATMASSINYNTVWSALFEPVPTFRFLRTLGRTSPE
                     AARHDQPYHVLGSDLSGVVLRTGPGVREWKPGDEVVAHCLQPDLQTPGGHDDTLLDPGQ
                     RVWGYETNFGGLAELSLVKANQLMPKPAHLTWEEAASLGVALSTAYRQLVSHHGAAMKQ
                     GERVLVWGAAGGVGAYATQLALNGGAVPICVVSSQAKADLCRQMGAELVIDRAAEGFSF
                     WEGRDRPRLSEWSRFRGAVRSLAGDDPDIVIEHPGRDTFGVSVMIAARGGKVVTCASTT
                     GYQHTYDNRHLWMRVKRIIGSHMANYREAWAANELVARGSIHPVLSRVYPLDATGDATH
                     AVANNSHHGKVGVLCLADRPGMGVRDPELRARKLDSINLFRKGQPR"
     aSDomain        6615..7694
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_allR_PKS_ER.1"
                     /evalue="1.20E-23"
                     /label="allR_PKS_ER.1"
                     /locus_tag="allR"
                     /protein_end="410"
                     /protein_start="50"
                     /score="75.5"
                     /tool="antismash"
                     /translation="TVQVQEVPTPEPDHGEVLIATMASSINYNTVWSALFEPVPTFRFL
                     RTLGRTSPEAARHDQPYHVLGSDLSGVVLRTGPGVREWKPGDEVVAHCLQPDLQTPGGH
                     DDTLLDPGQRVWGYETNFGGLAELSLVKANQLMPKPAHLTWEEAASLGVALSTAYRQLV
                     SHHGAAMKQGERVLVWGAAGGVGAYATQLALNGGAVPICVVSSQAKADLCRQMGAELVI
                     DRAAEGFSFWEGRDRPRLSEWSRFRGAVRSLAGDDPDIVIEHPGRDTFGVSVMIAARGG
                     KVVTCASTTGYQHTYDNRHLWMRVKRIIGSHMANYREAWAANELVARGSIHPVLSRVYP
                     LDATGDATHAVANNSHHGKV"
     CDS_motif       7131..7193
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_allR_0001"
                     /evalue="6.10E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="allR"
                     /protein_end="243"
                     /protein_start="222"
                     /score="15.7"
                     /tool="antismash"
                     /translation="GERVLVWGAAGGVGAYATQLA"
     gene            7799..8959
                     /gene="allD"
     CDS             7799..8959
                     /codon_start=1
                     /gene="allD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 252.7; E-value:
                     1e-76)"
                     /gene_kind="biosynthetic-additional"
                     /note="acyl-CoA dehydrohenase"
                     /product="AllD"
                     /protein_id="ADG39434.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 6.1e-18, bitscore:
                     55.1, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.8e-20, bitscore:
                     62.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 9.6e-28, bitscore:
                     86.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSESERLGIVRDFVAREILGREGILDSLADAPLALYERFAETGLM
                     NWWVPKEHGGLGLGLEESVRIVSELAYGDAGVAFTLFLPVLTTSMIGWYGSEELKERFL
                     GPLVARRGFCATLGSEHEAGSELARISTTVRRDGDTLVLDGTKAFSTSTDFARFLVVIA
                     RSADDPARYTAVTVPRDAPGLRVDKRWDVIGMRASATYQVSFSDCRVPGDNALNGNGLR
                     LLEIGLNASRILIAASALGVARRIRDVCMEYGKTKSLKGAPLVKDGVFAGRLGQFEMQI
                     DVMANQCLAAARAYDATAARPDAARVLLRQGAQKSALTAKMFCGQTAWQIASTASEMFG
                     GIGYTHDMVIGKLLRDVRHASIIEGGDDVLRDLVYQRFVVPTAKRT"
     gene            complement(8972..10126)
                     /gene="allM"
     CDS             complement(8972..10126)
                     /codon_start=1
                     /gene="allM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168:O-succinylhomoserine sulfhydrylase (Score: 319.8;
                     E-value: 3.3e-97)"
                     /gene_kind="biosynthetic-additional"
                     /note="methionine gamma lyase"
                     /product="AllM"
                     /protein_id="ADG39435.1"
                     /transl_table=11
                     /translation="MPSHHWETRAVHAGREDLVDLGLHVPPIDLSTTYPSRDTVAEAAR
                     IDVFGSGADDGGPPIYGRAGNPTVARFESALAELEGAEAAVAFASGMAALCACLLVQVA
                     RGRPHIVAVRPLYGTSDYLLDSGLLGTSVTWAQPHSAGDAIRSDTGLVIVESPANPTLT
                     ETDIQALAAACAPVPVLVDNTFATPALQRPLNRGAAIVLHSATKYLGGHGDVMGGVVAS
                     NEEFARALRRIRFATGGILHPLAGYQLLRGLSTLSVRMHHASASAAEIARRLLHHPAVT
                     RVHYPGLSGEPRPPKQMAAGGAIVSFEVDDPHAVTGGVRLFTPAVSLGSVDSLIQHPVS
                     LTHHAMDPGSREQAGISDRLLRISVGLEHVDDLWADLTQALTRD"
     gene            10186..10653
                     /gene="allN"
     CDS             10186..10653
                     /codon_start=1
                     /gene="allN"
                     /gene_functions="regulatory (smcogs) SMCOG1120:AsnC family
                     transcriptional regulator (Score: 134.6; E-value: 3.4e-41)"
                     /gene_kind="regulatory"
                     /note="putative transcriptional regulator of AsnC family"
                     /product="AllN"
                     /protein_id="ADG39436.1"
                     /transl_table=11
                     /translation="MKEKVVLDSIDQAILRELQNDGRLPNKTLARRVGVAPSTCLARTQ
                     RLMEAGVIRGFQAQVSAAAIGRQVQAVLAVQFIAHSRPFVDPFVAWARERPETRALHHV
                     TGAFDFLVHTACRDTENLQQLVLEFTARREVGRVETHLVFGSWSGGPLTPG"
     gene            10757..11986
                     /gene="allP"
     CDS             10757..11986
                     /codon_start=1
                     /gene="allP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 370.8; E-value:
                     1.3e-112)"
                     /gene_kind="biosynthetic-additional"
                     /note="P450 monooxygenase; putative cytochrome P450"
                     /product="AllP"
                     /protein_id="ADG39437.1"
                     /sec_met_domain="p450 (E-value: 5.4e-11, bitscore: 31.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDREPVFVLDPRGGDRHGEDAALRARGPLTRVDALGVEAWSVTDP
                     VLLRRLLLDSRVSKNARQHWPAFPEEIVGVWPLALWVAVENMFTAYGEEHRRLRRTIGP
                     AFAARRINALAPVIEQLVGELLDELAATPPGEPVDLREHFAYPLPIGVVGQLAGLPESV
                     RPRFRRTVDVIFSTSHSPEETTAAVQDLYALLADLVAAKRAEPGDDLTSALIAARDTEG
                     DGEPLTEAELVDTLLLVVNAGFETTVNLLDQAITALLTDPGQLAHVRAGRAGWKDVVEE
                     SLRHEAPLAHLPMRFAVEDIPLPEHGVTIRQGDAVLPAYAAANRHPDLHGLTADDFDAT
                     RSDKSHLSFGHGMHLCLGAALGRLEAEIALRGLFERFPRLALAVPLDRLRPKPSFISNG
                     HSELPVIIDP"
     gene            12171..13358
                     /gene="allO"
     CDS             12171..13358
                     /codon_start=1
                     /gene="allO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191:acyl-CoA dehydrogenase type 2 (Score: 332.9;
                     E-value: 3.4e-101)"
                     /gene_kind="biosynthetic-additional"
                     /note="acyl-CoA oxidoreductase"
                     /product="AllO"
                     /protein_id="ADG39438.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 6.1e-10, bitscore:
                     29.3, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.9e-09, bitscore:
                     26.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTPQPDVAEGLTPVEAARSLVPLLAAEAARTEERRALTGATVTG
                     LRRAGLLRLGTPTECGGRGAGARTAVDVCEELAKGCASASWIVGIAYGGALFASQLPHS
                     ERAALWRDDPDAVVCGSANPSGTARRTDGGWTLSGRWPWISGIHHAPWTLLGFVRPGAG
                     GEPERGMAVVPTAGLTVEDVWHMAGMRGTGSDTAVADGVYVPDSRTISLTAMADGAYRR
                     RHPGEPRVTFHLSINLPLVATAVGIATASLEKVLDAAARGKQTVSPLHRLVAEDSAHQL
                     NVADAATLIDTARLHLRRAADEVDSHARAGRRPALAERARLRMDAAHAMRCARDAVSLL
                     LDTAGAGSFADGSVLQRAWRDIETASRHAALSVQTSKEIYGRALLGAPLPPGPVV"
     gene            13467..14123
                     /gene="allS"
     CDS             13467..14123
                     /NRPS_PKS="Domain: PKS_KR (27-132). E-value: 3.3e-09.
                     Score: 28.7. Matches aSDomain:
                     nrpspksdomains_allS_PKS_KR.1"
                     /codon_start=1
                     /gene="allS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     180.5; E-value: 6.8e-55)"
                     /gene_kind="biosynthetic-additional"
                     /note="putatative acetoacetyl-CoA or acetoacetyl-ACP
                     reductase"
                     /product="AllS"
                     /protein_id="ADG39439.1"
                     /transl_table=11
                     /translation="MALLDRDGDAVTGLSAALDPAGAGTALPLRADVDDTDAVHAALRE
                     TAAAWHAPDILINNAARTAPGSVWDIEPDEWDAVLTTNLRSVLTLTRLCAPAMRDRGWG
                     RVVNLSSLAGQQGGTLAGAHYSAAKAGVLVLTKVFARELAAHGVTVNAVAPAAVDTPAV
                     AGLGPSAVAEAARQIPVGRMGRPSEVAGLVAYLVGEEGGYVTGATFDINGGTHMR"
     aSDomain        13548..13862
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_allS_PKS_KR.1"
                     /evalue="3.30E-09"
                     /label="allS_PKS_KR.1"
                     /locus_tag="allS"
                     /protein_end="132"
                     /protein_start="27"
                     /score="28.7"
                     /tool="antismash"
                     /translation="PLRADVDDTDAVHAALRETAAAWHAPDILINNAARTAPGSVWDIE
                     PDEWDAVLTTNLRSVLTLTRLCAPAMRDRGWGRVVNLSSLAGQQGGTLAGAHYSAAKAG
                     V"
     gene            14295..14963
                     /gene="fkbG"
     CDS             14295..14963
                     /codon_start=1
                     /function="FK-506 biosynthesis"
                     /gene="fkbG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Methyltransf_3"
                     /gene_kind="biosynthetic-additional"
                     /product="FkbG"
                     /protein_id="ADG39440.1"
                     /sec_met_domain="PCMT (E-value: 2.5e-08, bitscore: 23.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="Methyltransf_3 (E-value: 4.5e-63,
                     bitscore: 201.6, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANQVTMSDALLAYVRKVSLRDDRVLGGLRAESAGLPGGNALPVS
                     AEEGQFLEFLVRLTGARQVLEIGTYTGYSTLCLARGLPPGARVVTCDNTAKWPEVGRPY
                     WERAGVAERIDVRIGDALDVLAGLRDEPGAGPGSFDVVFIDADKERYPAYYEAALPLVR
                     GGGLIVVDNTLFFGRVADDAVTDPETTAIRALNAGLRDDDRVDLAMLASADGITLLRKR
                     "
ORIGIN
        1 agcacctgca ctcaacggat gaggggcctc gacagggtgt ccccgagggc gaaccgcgta
       61 tcggaacagg ggtagcggat gctggaagtc tttgccggat tgagcggtgt cgtcgtactg
      121 ctgggaacac gtctggcgta tcagtggatc cggggtcgga cggaggtcga gctggcccgg
      181 gtggcccggg agaccgcggc cggtctgccg ccgggcagtg tgctcaccga tcggcgcccg
      241 ggcagcgagc tacgggtgca gatcgggccc ggattccggg ggcagtcgca tggctgaggc
      301 cccgggccac cccgccgtcc cggtggcgca gccgttacgc ccgcccgacc cggacacacg
      361 gccgggcgcc gagttcgccc gctactacga acagcagatg ccccggctgc tcattcatct
      421 ggtccgccgg ggggcgagct ggcacgaggc cggggaagcc gcccaggccg ccttcaccga
      481 ggcgttcacc cagtgggatc gcatcgcaca ccccgccggc tggctgcggc tggtcgccta
      541 ccgcctctat ctgcgccgcc ccgcacgccg ggaggagccc accgaccagc tgcccgacgg
      601 gcccggaggc agctgtccgc tgcacaaggt ggaactgaag gagtccgagc agtgggtcct
      661 gtccgctctg tcggccctgc cgtcgcagca gagcgcggtc atggcctggc acctcgacgg
      721 cttcgccacc cgggagatcg cggaggccct cgggaccacc ccggcagcgg tacggcagaa
      781 cctcgccagg gcccgcgccc ggctcaagac gatcctgctc gcacccaccg accggacagg
      841 agacggaggc cgggaatgac gatccacgac gacgatgacg cagcactcga cgcgctgctc
      901 gacgccgccg acgacggcct gcgcgctgcg gtcgcggcga gcctggacgc cgacgcaggc
      961 cgtgccgcga tcttcacccg ggcactgccg ccccaccgcg acgcgctccc accggcggac
     1021 aatatgttcg gcggccacac cacgatccac tgggccgatg cgatcgacac cgacccccac
     1081 gtcagccgga tcctggagct tctgtccgag gccctgaacc gcctctcgga gctgggctgc
     1141 tggctccgga ccccgggcgg cccgggaacc ccaccgggcc ggacggagac cgccgccacc
     1201 ctgctgaccg ccctgtggct gggggtcaag gaacggggcg tcgaccagcc caccgcccag
     1261 accttcgtgg gcgtcggcct cgacgagatc cgtgaactgc ggaacgagct gaggaggtcc
     1321 gtcggatcgg ggcggcagct acggcccgat ccctgggaca gctgggacgg ccagtgggcc
     1381 gacgcccact gtcaccggct gcacaccacc ctgcagaccg cccggaatct gctcccggac
     1441 ctcttccgcg acggcagcga gacctcctcc gtgcccctgt cgagccgttg aatccgcggc
     1501 gccgcggtga ccggaaggca cccgcgggcc cgcccgtgat ctactgacag gaatcggccg
     1561 cagcagcggc tgcagcgggg ctacgacagg gctacgacgg gggaacgacg cgatgttcgg
     1621 attccggggg cggcggaacg atccgccggc cgagcgcgcc aggggcgggg gcgcggagct
     1681 ggtcctgccg tccgccgatc cggtcgagcg ggcggaggcg ctgagctggc tccaggagca
     1741 cgcgcgcgag tatctcgacc ccggtgccct cgccgaccgt gaggatctgc gccggtgacc
     1801 ccctccgagc ggccggcccc gcgctacctc gcccatacgt cactggtctg gcggctgctt
     1861 ttcggcacgg tcggcggccc ctggcccgag cgggtcgccg aagggctcgt gaccatctgc
     1921 cccgtcaccc atgccgaact ccggcacggt ctgcaccccg gtacggaccc cttgcccctg
     1981 catctggcgc tcgaccgggc cttcggctcc gtcccgctga ggcacttcga caagcagccc
     2041 gaagccgccg acgtgggcaa gcggctgcgc gcgctcggcg tcgggcagcc gccctccctg
     2101 atggacatcg tgaccgcgct caccgcacgc gaccacggtc tgaccctcgt ccacaccatc
     2161 gaccgcttcg acagcatcaa ccgggtgtgc cccgatatct ccctgatcaa ggtgcaggcg
     2221 gcccgccctc cgcgccccga gccctcccgg gacaccaacc ggcggcgggg cttcctgcgc
     2281 agcctcctgg acgactgacc cggccccacc ggccccgagc ggccctcagc ggcccggacc
     2341 ccgccccgac cggggcccgc gtacagccgc cggagtccgc ggcacgggca gcccggcggc
     2401 cgacccgttc ccggacaagg gccctcccac cgccccccta ggcatctgtc ccatggtcgc
     2461 ttaggggggt ccggcctgcc gtcctagggg gctgacgggc cgacgaagcc ctccctatgc
     2521 tcgggtcgtt cgttacgggg agacggcatc ccggagccgc cgcggccact cttcgaccac
     2581 cggtgggtcc ggtacgcggc ggacccgtcc cctcgtcccg cgctaccgca cctccatccc
     2641 gatcatgccc ctcctgtccg gccggagcat gtccagcggc atgtccgacg gttccccctg
     2701 cccggcagga gaagcgccgg cccgagctgt ccgggcggga ccggcccggg ccatcccgac
     2761 gaaaggacga tgacatgacc agtggggtgg cgttcctctt ccccggccaa gggtcgtacg
     2821 taccgggcgt cttcgccggt ctgggtgccg atgccggccg ggtggcgacc ctcgtcgcgg
     2881 agatcgacgc ggccgtcgag gagttccggc tgaagccggt ccggccgctt ctgttctccc
     2941 cggacgctcc ggcgctggcg gagctgctcg aatccgatca cgagcggctc gacgtggcca
     3001 tcctggcaac ctccatcgcc ctggcggagc ttctggagtc acggcacggg atgagtcccg
     3061 accatgtcgc cgggcacagt ctcggggagt tcggagccct cgccgtcgcc ggtgtcttca
     3121 ccccgggcga cgcggccagg gcggtctgcg aacgccacgc cacgctgcgc aaggcgccgc
     3181 cgcccacggg cgggatgctg gcggtgaagg cggacgcggc ccgcgccggg gagctgatcg
     3241 ctgccgcgcg ggccgggacg tcggccgtat cggcgctgaa ctcccccagc cagacggtga
     3301 tcagcggcgc ggaagcggat ctggtgaagg tgcagcagct ggcacgggag gaaggcatcc
     3361 gtacctcccg gctgcatgtc cccggcccct tccacgtccc gcagctggcc gacgcgagcg
     3421 ccctgtacgc gacgacgatg cgcaccatac ggatatccgc gccccgggag cgcttcttct
     3481 actcccacgg tctgggccgc ttcctgacgg cgcaggacga tgtcgtcgac ctgatggtga
     3541 acgacatgac ccgtccggtg cggttccacg actccgtacg cgcgctgaac gcggagggcg
     3601 tcacgaccta tgtggagtgc ggtgcgctgg acgtcctcac ccggatcgtg tccggatcgc
     3661 tgccccgcgc cgtgaccctg gcaccgctcc gggaggccac gacgacaccg gatctgtccg
     3721 cccggctgcg gcccgccggc accccggccg tgaacggcgt cgctgcgccc gcgggcccgg
     3781 cgccggccgc cgaggtcgac ccggaggtgc tcgcgggggt acgtgcggtg tgcgccgagg
     3841 tcctggagta tccgctggag gtgatcaccg acgacgcgga cttccaggcc gatctcggtg
     3901 tcgactccct ggcgatgacc gagctgcagg cccacgcgct gcagcggttc ggtctgaagg
     3961 agacgctgca ggacgcggat acgggaacgt acggcacggt ttccggtctg gccgcgtaca
     4021 tcacgggcct gctgagtgag ggcaccggtt ccgtttccgg gcggcggtga tccggtcgtg
     4081 atctcccgtg ctccggacgg ggaggggccg cacgacgaca gggtcgccgt cgtcgggatg
     4141 ggtgtcgccg tgccgggcgc ctgcgacccg gaggagctgt ggaagctgct gtgcggtgac
     4201 agacccgtgt tcgatgagcc gtcggaccgc ttccggctcg attccttctg gtccgcggat
     4261 ccggccgccg aggaccgcgg ctatgtccgc acttcgggtt ttctgcacga cttccgtccg
     4321 caccccgcac tggccgcgga gatcgcggcc ggaacgctct cggccgccgc gcagaacccg
     4381 gtctggctgc ggcactgcct gctgcaggcg cgggacaccg tcaccgcccg cagcaccgac
     4441 cgatacgcct accacgtcgg gaccagcgcc ctggtcggcc agcgcaccga cgaggcggtg
     4501 ctggccgagt gcgttccccg ggccgtcgcc gagcggctgc accgcgacga gcccgcccgg
     4561 atggccgagg ccgaggcacg gctgcgcgcc ctgctgagaa gccaccacgg gtacggcgcc
     4621 gaagagccgc gggacacact gcccgaccgg gtcgtacggg ccgcggcggc cggactgtta
     4681 cccgacgact gcgagttctc cgtggtcgac gcggcctgct cgtcctcgct gtacgcgatc
     4741 ggtctgggtg tcgcgagcct gctggcgggc gcctgcgata tcgcctactg cggcggggtg
     4801 tcgggagtga cgccgcgtta caacgtcacg ttctccaaac tgcacgggct gagccccagc
     4861 ggcgacgtcc gcgcgttcga cgacgacgcc gacggaacgc tgttctcgga cggagcgggc
     4921 gttgtcgcgc tgaagcgcct ggaccgggcc gtcgaggacg gggacccggt gttcggcgtc
     4981 ctcgtgggat tcggcgggtc gtcggacggc cggggaacgg cgatctacgc ccccaacccc
     5041 gtcggtcagc gccgctgcct ggaccgcgcc cggcaggcat cgggtctcac ggcggacgat
     5101 gtcgactggg tcatcgcgca cgggacgggc acggccgtcg gtgacgcggt cgagctgcgg
     5161 accctcgccg ccgccaccga tccgggcagc gtctggtgcg gatccaacaa gtccctgctc
     5221 ggtcataccg ggtggagctc cggagtggtc tcggtcgtcc aggccctcac ggcgctgcgg
     5281 cagggcacga taccggcaca gcgacgcttc accggtcccg ggctcaccgc gcagaccggc
     5341 gaccgggtac gcataccttc ggcggacgtt ccctggcatg cgggcggccg gcgttccagg
     5401 accgcaggcg tctccgcctt cggcttcggc ggcaccaacg cccatctgct gatcaccgac
     5461 cgagagcccg tgcggacggg cccgcgcccc gcccgcaccg ggcccgatcc ggtggtcgtc
     5521 ctcgcctgga ccgcgcacct gcccggcgac cccggccccg aggcgacgga gcggctgctg
     5581 cgcgaaggcc gcatccccgg gccgcgtacc ttcggccccc gctatccggc gcccccgttt
     5641 ccggacgtcc gtctccctcc gcccaccgta cggtccacgg acgcgggcca gctcatggcc
     5701 ctgcgggtgg cgggcctgtt cgccgccgaa cacggtgagc tgtgggcgcc ggtacgggcg
     5761 accaccgggg tcttcgcggc cgccaccggt ccgccgccgt cctccatgga tcatctggtg
     5821 cgctgtcatg ccgccgacgt acaccgcatt ctcgacgaac ccgaccggac ggcgttcacc
     5881 gaatggctcg ccgacctgcg ggccacgacc ccggcgacca ccaaggacac gctgccgggg
     5941 ctgctgccca acatcatccc ggcgcgtatc gccaaccgct acgacctggg cggccccacc
     6001 atgctggtcg acacgggcac caccagcggg ctcaccgccg tgcacaccgc cgtccgccaa
     6061 ctggcggccg gtgccgtcga catggcgctc gtcctcggtg tcagcgcgac cggccgaccc
     6121 gagttcgccc gcttcatggg cgtcgcggcc gagcggatcg cggagggggc gttcctcctc
     6181 gcgctgagtc gcgagtccgt cgccctcgcg cacggcctga cccccctcgt ccgcctccgc
     6241 acggactgga ccggcagccc tcaggcgtct gcggatgccg tccccggcgg gcccggtgcg
     6301 gcggaggaca ccttcctcgg cgccgacggc gtcctcgccg tgatccgtgc cctgcactcc
     6361 accgcgtccg gcgtcaccgt gggacccgcg gacggcgaac cgggcccggt gatcaccctc
     6421 tcccccgccg acggctcacc tcttcggcag acaaggacca gccgatgacc cacgttcgcg
     6481 acgccgcggc caccgacgac ccgcaggcca tcgccgcctg cgaggtcccg gccggctacc
     6541 gggccgccgt tgtcctcgcg gccgaccacc aggcactcgc cgggagcccc gtcgaagacc
     6601 gggacccccg caagacggtc caggtccagg aggtccccac ccccgaaccg gaccacggcg
     6661 aggtgctcat cgccaccatg gcgagctcca tcaactacaa caccgtgtgg tcggcgctct
     6721 tcgagcccgt tcccaccttc cgctttctgc gcaccctcgg ccgtacctca ccggaggcgg
     6781 cccgccacga ccagccgtac cacgtgctcg gctccgacct gtccggagtg gtgctgcgca
     6841 ccggaccggg tgtacgggag tggaagcccg gcgacgaagt cgtcgcgcac tgtctgcaac
     6901 cggacctgca gacgccgggc gggcacgacg acaccctgct cgaccccggc cagcgggtct
     6961 ggggctacga gacgaacttc ggcggcctcg ccgaactctc cctggtcaag gcgaaccagc
     7021 tgatgccgaa gcccgcccat ctcacctggg aggaggcggc ctccctgggg gtggcgctct
     7081 ccacggccta ccgtcagctg gtgtcccacc acggggcggc gatgaagcag ggcgagcgcg
     7141 tcctggtctg gggtgccgcc ggtggcgtcg gcgcctacgc gacccagctg gccctcaacg
     7201 gcggcgccgt tccgatctgt gtggtgtcgt cgcaggccaa ggccgacctg tgccggcaga
     7261 tgggcgcgga gctcgtcatc gaccgtgctg cggagggctt ctcgttctgg gaggggcggg
     7321 accgcccgcg gctgagcgag tggagccgct tccgcggtgc cgtccggtcc ctggcgggtg
     7381 acgacccgga catcgtcatc gagcaccccg gccgggacac cttcggcgtc agcgtcatga
     7441 tcgccgcccg gggcggaaag gtggtcacct gcgcatcgac caccggctac cagcacacct
     7501 acgacaaccg ccatctgtgg atgcgcgtca aacgcatcat cgggtcacat atggcgaact
     7561 accgggaagc ctgggccgcg aacgaactcg tcgcacgcgg cagcatccac cccgtgctct
     7621 cccgggtcta ccccctcgac gccacaggcg acgccacgca cgccgtcgcc aacaacagcc
     7681 accacggcaa ggtgggcgtg ctctgcctcg ccgaccgccc cggcatggga gtgcgcgacc
     7741 ccgagctgcg ggcccggaaa ctcgacagca tcaacctgtt ccggaagggg cagccccggt
     7801 gagcgaatcc gaacgcctcg gtatcgtcag ggatttcgtc gcccgggaga tcctgggccg
     7861 cgaaggcatc ctcgactcgc tggcggacgc accactggcc ctgtacgaac gcttcgccga
     7921 gacgggcctg atgaactggt gggtccccaa ggagcacggc ggtcttgggc tcggcctgga
     7981 agagagtgtg cggatcgtct ccgaactcgc ctacggggac gccggggtgg cgttcaccct
     8041 gtttctgccc gtcctgacga ccagcatgat cggctggtac ggcagcgagg agctcaagga
     8101 gagattcctc ggccctctcg tggcccggcg gggcttctgc gccacgctgg gcagcgagca
     8161 cgaggccggc agcgaactgg cccggatctc caccacggtc cgccgtgacg gcgacacgct
     8221 ggtactcgac ggcaccaagg ccttctccac cagcaccgac ttcgcccggt tcctcgtcgt
     8281 catcgcccgt tcggcggacg acccggcccg gtacacggcg gtcaccgtac cgcgggacgc
     8341 gccggggctg cgggtcgaca aacgctggga cgtcatcggg atgcgcgcct ccgcgaccta
     8401 tcaggtgtcg ttctccgact gccgggtgcc gggggacaac gcgctgaacg gcaatgggct
     8461 gcggctgctg gagatcggcc tcaacgccag cagaatcctg atcgccgcat ccgctctggg
     8521 tgtcgcccgc aggatccgcg atgtgtgcat ggagtacggg aagacgaagt cgctcaaggg
     8581 cgctccgctc gtcaaggacg gcgtgttcgc cgggcggctc ggccagttcg agatgcagat
     8641 cgacgtgatg gcgaaccagt gcctggcggc cgcacgggcc tacgacgcga ccgcggcccg
     8701 gcccgacgcc gccagggtgc tgctgcggca gggcgcccag aagtcggcac tgaccgcgaa
     8761 gatgttctgc gggcagacgg cctggcagat cgcgtccacc gcgtcggaga tgttcggcgg
     8821 catcgggtac acgcacgaca tggtgatcgg gaagctgctg cgggatgtgc ggcacgcttc
     8881 gatcatcgag ggcggcgacg acgtcctgcg cgatctcgtc taccagcgct tcgtcgtccc
     8941 caccgcgaaa cgtacctagg gcatgttctg gtcagtcccg cgtcagggcc tgggtgaggt
     9001 cggcccacag atcgtcgacg tgttcgaggc cgacggagat ccggagcagt cggtcggaga
     9061 taccggcctg ttcgcgtgag cccgggtcca tggcgtggtg ggtgagcgag accgggtgct
     9121 gaatgaggct gtcgacgctg ccgaggctga ccgccggggt gaagagacgt acgccgccgg
     9181 tcaccgcgtg cggatcgtcg acctcgaagg acacgattgc cccgcctgcg gccatctgct
     9241 tcggcggccg gggttcaccg ctcagccccg ggtagtggac cctggtgacc gccggatggt
     9301 gcaggagccg gcgggcgatc tcggcagccg aggccgaagc gtggtgcatc cgcaccgaga
     9361 gcgtcgacag tcctctgagg agctggtagc cagccagggg gtgcaggatc cctccggtgg
     9421 cgaaccggat ccgccgcagg gcacgggcga actcctcgtt cgacgccacc acaccgccca
     9481 tgacgtcacc gtggcccccc aggtacttcg tcgcgctgtg cagaacgatg gcggcacccc
     9541 tgttcagggg gcgctggagc gcgggcgttg cgaaggtgtt gtcgaccagt accggaaccg
     9601 gagcgcatgc agcggccagc gcctggatgt cggtctccgt cagtgtgggg ttggcgggtg
     9661 actcgacgat caccagcccc gtgtcgctgc ggatggcatc gccggcgctg tggggttgcg
     9721 cccaggtcac cgaggtgccc agcaggcccg agtccaggag gtagtcgctg gtgccgtaca
     9781 ggggacggac ggcgacgata tgcggccgtc cccgggcgac ctgcacgaga aggcaggcgc
     9841 agagcgctgc cataccgctg gcgaaggcca ccgcggcttc ggccccttcc agttcggcca
     9901 gcgcggactc gaaccgtgcg acggtggggt tccctgcccg gccgtagatc ggcggaccgc
     9961 cgtcgtcggc tccggagccg aacacgtcga tccgcgccgc ctcggcaacg gtgtcgcggg
    10021 aggggtaggt ggtggacagg tctatgggcg ggacatgcag tccgagatcg acaagatcct
    10081 cacggccggc atggaccgcc cgggtttccc agtgatgcga aggcatgacg acagtcttcg
    10141 caaagcgtca ggatcagtga ctgaatctcg cactacattc ggtccatgaa agaaaaggtt
    10201 gtcctggatt cgatagatca ggcaattctg cgtgagctgc agaatgatgg tcggctgccc
    10261 aacaagacgc tggcccggag ggtcggcgtg gcaccgtcca cctgtctggc ccgcacgcag
    10321 aggctgatgg aggcaggtgt gatcagaggt ttccaggctc aggtgagtgc cgcggcgatc
    10381 ggccggcagg tccaggccgt cctcgccgtc cagttcatcg cccattcacg tccctttgtc
    10441 gacccgttcg tggcatgggc cagggagcgg cccgagactc gtgcgcttca ccatgtgacc
    10501 ggagccttcg acttcctcgt ccacacggcc tgccgtgaca ccgagaacct ccagcaactc
    10561 gtcctggagt tcaccgcacg ccgagaggtg ggccgagtgg agacccacct cgtattcgga
    10621 tcctggtcgg gaggacccct gactccgggc tagtgatctg aatcggagat tcgtcggcag
    10681 gtcgggcggg cgccgatgtc ccgccggtac agtcgccacc gtcgttccat ccaccctctg
    10741 tctccaagga gacctcgtgg accgagaacc cgttttcgtc ctcgacccgc gcggcggcga
    10801 tcgccatggc gaggacgccg ccctccgcgc ccgcggcccc ctgacccgag tcgacgccct
    10861 cggcgtggag gcgtggtcgg tcaccgaccc ggtgctgctc cgtcggctgc tgctggactc
    10921 gcgggtctcc aaaaacgccc ggcaacactg gcccgccttc ccggaggaga tcgtcggagt
    10981 ctggccgctc gccctctggg tcgccgtgga gaacatgttc accgcctatg gcgaggagca
    11041 ccgacggctg cggcggacca tcgggccggc cttcgccgcc cgcaggatca acgcgctggc
    11101 gccggtcatc gagcagctcg tgggggagct gctggacgag ctcgccgcca ccccgcccgg
    11161 agagccggtc gacctgcggg agcacttcgc ctatccgctg cccatcgggg tcgtcggcca
    11221 gctcgccggc ctccccgaat ccgtccggcc ccggttccgc cgtaccgtcg acgtgatctt
    11281 ctccaccagc cacagccccg aggagacgac cgccgcggtc caggatctgt acgcgctcct
    11341 cgccgacctc gtggccgcca agcgcgccga gccgggagac gacctcacgt cggcgctcat
    11401 cgccgccagg gatacggaag gcgacggaga gcccctgacg gaggccgaac tcgtcgacac
    11461 cctgctgctg gtggtcaacg ccggtttcga aaccaccgtc aacctcctgg accaggcgat
    11521 caccgcactc ctcaccgacc ccgggcaact cgcccatgtc cgcgccggac gcgcgggctg
    11581 gaaggacgtg gtcgaggaat cactccgcca cgaggccccg ctcgcgcatc tgccgatgcg
    11641 cttcgccgtg gaggacatcc ccctccccga acacggcgtg accatccggc agggcgacgc
    11701 cgtcctgccc gcctacgccg ccgccaaccg gcatccggac ctgcacggcc tcaccgccga
    11761 cgacttcgac gccacccgga gcgacaagag ccatctctcc ttcggacacg gcatgcacct
    11821 ctgcctcgga gccgccctcg gtcgcctcga agccgaaatc gccctgcgcg gcctcttcga
    11881 acgcttcccc cgtctcgccc tcgccgtgcc cctggaccga ctgcgcccca agccgagctt
    11941 catctccaac ggccacagcg aactgcccgt catcatcgac ccgtagcccc cggccgacgg
    12001 cagggatgtc cgctctcaac agcacgggga tactctgatg aaccgcttcg cctcggacga
    12061 ggggctggac gacagagtcg cctactgact gcgaaggact tggaagcaca ccgagccgcc
    12121 gccccctccg ccccgtaccg gggcggcacg acgaaagggc agggacgact gtgggcactc
    12181 ctcaacccga tgtcgccgag ggcctcacgc cggtcgaggc ggcgcgctca ctggtcccgc
    12241 tgctcgctgc cgaagcggcc cgcaccgagg agcggcgcgc cctcaccggc gccactgtga
    12301 ccggcctgcg ccgggccggt ctgctccgcc tcgggacccc gaccgagtgc ggcggccggg
    12361 gtgcgggtgc ccgtaccgcg gtggatgtgt gcgaggagct ggccaagggc tgtgcgtccg
    12421 cctcctggat cgtgggcatc gcctacggcg gcgccctctt cgcctcccag cttccccact
    12481 ccgagcgtgc ggccctgtgg cgggacgacc cggacgctgt cgtctgcggc agcgccaacc
    12541 cgtccggaac ggcgcggcgt acggacggcg gctggaccct gagcggccgt tggccctgga
    12601 tctccggcat ccaccatgcg ccctggaccc tgctcggctt cgtccggccc ggcgcagggg
    12661 gcgaaccgga gcgcggcatg gccgtggtcc ccaccgccgg cctgaccgtc gaggacgtct
    12721 ggcatatggc gggcatgcgc ggcaccggca gcgacacggc cgtcgcggac ggcgtgtacg
    12781 tgccggactc ccgcacgatc tccctgaccg ccatggcgga cggcgcctac cggcgacgcc
    12841 atcccggcga accccgggtc accttccatc tctccatcaa cctgccgttg gtggcgacgg
    12901 ccgtcgggat cgccacagcg tccctggaga aggtgctgga tgccgcggcc cggggcaaac
    12961 agacggtctc cccgctgcac cggctggtcg ccgaggactc cgcccatcag ctcaatgtgg
    13021 cggacgccgc gacgctcatc gacacggccc ggctgcatct gcgccgcgcc gccgacgagg
    13081 tggactccca cgcccgcgcg gggcgccgtc ccgcgctcgc cgagcgggcc cgactgcgga
    13141 tggacgccgc ccacgccatg cgctgcgccc gcgacgccgt gagcctgctg ctggacaccg
    13201 cgggcgcggg cagcttcgcg gacggctcgg tcctgcaacg ggcctggcgc gatatcgaga
    13261 cggcgtcccg gcacgccgcg ctcagcgtcc agaccagcaa ggagatatac ggccgcgctc
    13321 tgctcggcgc cccgctgccg cccggcccgg tcgtctgagg ggggccacga tgacgacggc
    13381 aggcctccgg gtggcgctgg tcaccggcgc gggacgcggt atcgggggcc gcgatcgccg
    13441 aacggctgca cgggtccggc caccgggtgg ccctgctgga ccgcgacggc gacgccgtga
    13501 ccgggctgtc cgccgccctc gaccccgccg gcgcgggcac cgcgctgccg ctgcgtgcgg
    13561 acgtcgacga cacggacgcc gtccacgccg cgctgcgcga gaccgccgcc gcctggcacg
    13621 cgcccgacat cctgatcaac aatgccgccc ggaccgcccc cggctcggta tgggacatcg
    13681 aaccggacga atgggacgcc gtactgacga ccaatctgcg cagcgtcctg accctgaccc
    13741 ggctgtgcgc gcccgcgatg cgcgaccgcg gctggggccg ggtggtcaac ctctcctcgc
    13801 tggccggtca gcagggcggc accctcgccg gcgcccacta ctccgccgcc aaggcgggcg
    13861 ttctcgtgct gaccaaggtg ttcgcccgtg aactggcggc gcacggcgtg accgtcaacg
    13921 cggtagcccc ggccgccgtc gacaccccgg cggtcgccgg gctcggcccg tcggcggtgg
    13981 ccgaggcggc ccggcagatc ccggtgggcc ggatggggag gccttcggag gtcgccggcc
    14041 tcgtggccta tctggtgggc gaagagggcg gatacgtcac cggcgccacc ttcgacatca
    14101 acggcggcac ccatatgcgc tgacgcggcc ccgcgccctg cgatcgcgat gccgcccccg
    14161 aggcgccgct ggaccgtgtg gtcccgggtg ggtcccggcg ccgcaccgct acccccctcc
    14221 ccacccccct ggacccccct gacccggggg tccgggccgg gagggggacg ggacgcccgc
    14281 ctagcattcc gggcatggcg aatcaggtga ccatgtccga cgcgctgctc gcttacgtcc
    14341 ggaaggtgtc actgcgggac gacagggtgc tgggcggtct gcgggcggag tcggcagggc
    14401 tgccgggggg caacgctctg ccggtatccg ccgaagaggg ccagttcctg gaattcctgg
    14461 tgcggttgac cggcgcccgt caggtgctgg agatcgggac gtacaccggc tacagcaccc
    14521 tctgtctggc ccgcgggctg ccgcccgggg cccgggtggt gacgtgcgac aacacggcga
    14581 agtggccgga ggtgggcagg ccgtactggg agcgggccgg ggtggccgaa cggatcgacg
    14641 tacggatcgg cgacgccctg gacgtgctgg ccggactccg cgacgagccg ggcgcgggac
    14701 cggggtcgtt cgatgtcgtg ttcatcgacg ccgacaagga acgctatccg gcctactacg
    14761 aggcggctct gccgctggtg cgcggcggtg gcctgatcgt cgtcgacaac acgctgttct
    14821 tcggacgggt ggccgacgac gcggtgacgg acccggagac gacagcgatc cgcgcactca
    14881 atgcggggct gcgcgacgac gatcgggtgg acctggccat gctggcgtcg gccgacggca
    14941 tcaccttgtt gcggaagcgg tgaacgggat actgcccgcg gcggtcagtg tcagggtcct
    15001 cggcccgggt cgcggcgagg gctccagatg cagccgttcc acaccaccgg ccggctcccc
    15061 cagcggcgac gcgcaggcgc
//
