Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000887.1:
Cluster 1Alkaloid130991

BGC0000887, AWQC131C biosynthetic gene cluster from Dolichospermum circinale. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: Saxitoxin
PubChem ID: 37165
ChEBI ID: 34970
ChEMBL ID: 501134
ChemSpider ID: 34106
SMILES string: Copy to clipboard
Molecular formula: C10H17N7O4
Average molecular mass: 299.291 Da
Molecular activity: Other
Molecular target: Voltage-gated sodium channel

Class-specific details

Biosynthetic class(es):
Alkaloid subclass:

Gene cluster description

AWQC131C (BGC0000887). Gene Cluster 1. Biosynthetic class = Alkaloid. GenBank DQ787201. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Sequence-based prediction
Contact for this cluster:Brett Neilan (The University of New South Wales)

Literature references

1. Mihali TK et al. (2009) Characterisation of the paralytic shellfish toxin biosynthesis gene clusters in Anabaena circinalis AWQC131C and Aphanizomenon sp. NH-5. BMC Biochem 10:8. doi: 10.1186/1471-2091-10-8.
2. D'Agostino PM et al. (2014) Comparative proteomics reveals that a saxitoxin-producing and a nontoxic strain of Anabaena circinalis are two different ecotypes. J Proteome Res 13(3):1474-84. doi: 10.1021/pr401007k. Epub 2014 Feb