LOCUS       BGC0000893             22006 bp    DNA     linear   BCT 27-FEB-2015
DEFINITION  Streptomyces venezuelae ATCC 10712 complete genome.
ACCESSION   BGC0000893
VERSION     BGC0000893
KEYWORDS    .
SOURCE      Streptomyces venezuelae ATCC 10712
  ORGANISM  Streptomyces venezuelae ATCC 10712
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:23:30
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22006
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1035
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0913"
                     /db_xref="EnsemblGenomes-Tr:CCA54200"
                     /db_xref="InterPro:IPR003115"
                     /db_xref="UniProtKB/TrEMBL:F2RB72"
                     /locus_tag="SVEN_0913"
                     /old_locus_tag="SMD01675"
                     /product="transcriptional regulator protein"
                     /protein_id="CCA54200.1"
                     /transl_table=11
                     /translation="MSTISDLRQASTFDIDIHTLLPADSPRFALDQAHVRALAESETEF
                     PPILVHRATLRVIDGMHRVRAAKLRNRDTIGARWFEGDEQAAFLLAVESNTRHGLPLSS
                     DERKQAALRILRTHPHWSDRSIAERTGWSATGVGALRRDIADPDARPEARVGRDGRVRP
                     STTAEGRRVAAEVIRRNPDASLREIARQAGISVGTARDVRHRLAEGRPAVPDGRRADAP
                     PADPVAAPPGPGPDEDRTGRGGAPDLARRITLFDGLRNDPSLRLSESGRLVLQRLHAQL
                     RTTEEWKRLAPTIPLHGRSAVADILSACADDLKGMARELRCVEDSLTDHAASGSERRPD
                     AGPA"
     protocluster    1..22006
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[11177:14069]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      11178..14069
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..22006
                     /SMILES="NC(Cc1ccc(O)cc1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..22006
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000893"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..22006
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..1035
                     /locus_tag="SVEN_0913"
                     /old_locus_tag="SMD01675"
     misc_feature    343..345
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1040..1759)
                     /locus_tag="SVEN_0914"
                     /old_locus_tag="SMD01676"
     CDS             complement(1040..1759)
                     /NRPS_PKS="Domain: ACPS (105-169). E-value: 1.6e-20. Score:
                     65.3. Matches aSDomain: nrpspksdomains_SVEN_0914_ACPS.1"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0914"
                     /db_xref="EnsemblGenomes-Tr:CCA54201"
                     /db_xref="GOA:F2RB73"
                     /db_xref="InterPro:IPR003542"
                     /db_xref="InterPro:IPR008278"
                     /db_xref="UniProtKB/TrEMBL:F2RB73"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060:4'-phosphopantetheinyl transferase (Score: 232.9;
                     E-value: 4.8e-71)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SVEN_0914"
                     /old_locus_tag="SMD01676"
                     /product="phosphopantetheinyl transferase"
                     /protein_id="CCA54201.1"
                     /transl_table=11
                     /translation="MTPTLLTGLVPEAALTAEEFGDVPDAWIFPEEAAVLHRAADRRRR
                     EFATVRHCARLALTSLGRPAGPMVPGERGAPSWPEGVVGSMTHCDGYRAAAVSRRIDVA
                     ALGIDAEPHAPLPPGLLRRIASPTERAHLTELSRALPALHWDRLFFSAKESVYKAWFPL
                     TGTWLDFREAELVLDPYRQTFRARLLRTGHDDEGRPLHTLHGRWRVGRRLVVTAVAHRV
                     AAAALGGAGAAATAGRR"
     aSDomain        complement(1253..1444)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SVEN_0914_ACPS.1"
                     /evalue="1.60E-20"
                     /label="SVEN_0914_ACPS.1"
                     /locus_tag="SVEN_0914"
                     /protein_end="169"
                     /protein_start="105"
                     /score="65.3"
                     /tool="antismash"
                     /translation="LGIDAEPHAPLPPGLLRRIASPTERAHLTELSRALPALHWDRLFF
                     SAKESVYKAWFPLTGTWLD"
     gene            complement(1756..3174)
                     /locus_tag="SVEN_0915"
                     /old_locus_tag="SMD01677"
     CDS             complement(1756..3174)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0915"
                     /db_xref="EnsemblGenomes-Tr:CCA54202"
                     /db_xref="GOA:F2RB74"
                     /db_xref="InterPro:IPR006153"
                     /db_xref="UniProtKB/TrEMBL:F2RB74"
                     /gene_functions="transport (smcogs)
                     SMCOG1117:sodium/hydrogen exchanger (Score: 212.4; E-value:
                     1.6e-64)"
                     /gene_kind="transport"
                     /locus_tag="SVEN_0915"
                     /old_locus_tag="SMD01677"
                     /product="Na+ or H+ antiporter"
                     /protein_id="CCA54202.1"
                     /transl_table=11
                     /translation="MTTHQTAMIMMGLAVVLALAHVLGRLARRCGQPAVLGEILAGILL
                     GPTLFHGALSDAVFPTDVRPMLSTLGNLGVALFMFLVGLELDHRLLRGNKRAAVGVSVG
                     SIVCSFGLGAVLAVWLWNAHPVGDRLGFVLFLGAAMSITAFPVLARILTDRGIQHTRVG
                     ALAMASAAAGDVVAWLLLAAVLTFTGSQSSWQVLLVLPYAVAMVAVVRPLLGRYLTARE
                     PGGTGAGGHGRGVAGGERGVAGRGQGVAGGEQGTDRPGAGERGPGAGPLGVLTVLLLVS
                     GALSEWFGLHFIFGAFLAGAIVPRQGTERLRAAVADRFEAVTWMLLPAYFTVAGLKVDL
                     STVDADGLGELGLILLVAVGGKFGGAYLGARAAGRPGRSATTLGILMNTRGLTELIILG
                     VGLQLGLLDTDLYSLMVVMALVTTAMTAPLLRWAYPRQMVDADLRELAAEWEAAVPRPQ
                     AARAGGGKPSGAKR"
     gene            3487..4698
                     /locus_tag="SVEN_0916"
                     /old_locus_tag="SMD01679"
     CDS             3487..4698
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0916"
                     /db_xref="EnsemblGenomes-Tr:CCA54203"
                     /db_xref="GOA:F2RB75"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="UniProtKB/TrEMBL:F2RB75"
                     /gene_functions="resistance (resist) Chlor_Efflux_Pump
                     (Score: 357.2; E-value: 7.6e-109)"
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 338; E-value: 9.5e-103)"
                     /gene_kind="transport"
                     /locus_tag="SVEN_0916"
                     /old_locus_tag="SMD01679"
                     /product="major facilitator family transporter, putative"
                     /protein_id="CCA54203.1"
                     /transl_table=11
                     /translation="MPFAIYVLGLAVFAQGTSEFMLSGLVEDMAADFGVSLQAVGSLTS
                     AFAVGMIIGAPLVAMLSLRWPRRRALLAFLITFLLAHVVGALTNSFEVLFVTRVIAALA
                     NAGFLAVGLATAASMAGPQAKGRATSILLSGVTLACIAGVPLGAVLSEVWGWRSAFWGV
                     AIISAPAVFAVLWSVPATPVDPSAPSVRHELRALRTPKVGVTLLLGALVNGATFCSFTY
                     LAPVITNVTELSSGWVPATLALFGIGSFVGVNVGGRLADTRPGQVLAVGGAALLAGWLV
                     FALTAGNPVVALVLVFVQGALSFGVGSTLIAQALYTASDAPTLAGGFATAALNVGAAAG
                     PALGGLALGAEFGYRSPLVVSAVLVATALVLAGVARAAGVTGAKADAAATENPPTGRPV
                     EARS"
     gene            complement(4802..6064)
                     /locus_tag="SVEN_0917"
                     /old_locus_tag="SMD01680"
     CDS             complement(4802..6064)
                     /EC_number="2.5.1.54"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0917"
                     /db_xref="EnsemblGenomes-Tr:CCA54204"
                     /db_xref="GOA:F2RB76"
                     /db_xref="InterPro:IPR002480"
                     /db_xref="UniProtKB/TrEMBL:F2RB76"
                     /locus_tag="SVEN_0917"
                     /old_locus_tag="SMD01680"
                     /product="2-keto-3-deoxy-D-arabino-heptulosonate-7-
                     phosphate synthase II"
                     /protein_id="CCA54204.1"
                     /transl_table=11
                     /translation="MTPPVRTTPYDPHHSPAGGVPTRAEETTMHATTTLAALTGRTAAQ
                     QPYWPDPDAVDTVERELAGLPVLTPEDEVVDLMNGMALVARGAALLVQGGDCAERFHEA
                     VPDLVRRKVDNLQGLAAIMRAGSGLPAVALGRIAGQYGKPRSSPFETEESGAGRKMPSY
                     CGDAVNEPEFEPAARTPEPRRLLTAYTCSQIVLDEIRRSWSGRPVLERVYTSHELLLLP
                     YERPLVREGAHGTYSGSAHFGWIGERTRREDGAHVALAQAVHNPVGVKLGPTVSPEDAV
                     ALSRSLNPEGVPGRLTFIVRFGAKEVDELLPPVVRAVARHGAPVVWLCDPMHGNGLKLA
                     GHKTRLIEPMRAETAAFVRTLREHGQWPAGLHLELTPDPVTECVSELDRPPRFTDYRST
                     CDPRLNPEQSADMVTHFLSLL"
     gene            complement(6061..6372)
                     /locus_tag="SVEN_0918"
                     /old_locus_tag="SMD01683"
     CDS             complement(6061..6372)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0918"
                     /db_xref="EnsemblGenomes-Tr:CCA54205"
                     /db_xref="GOA:F2RB77"
                     /db_xref="InterPro:IPR002701"
                     /db_xref="InterPro:IPR008241"
                     /db_xref="InterPro:IPR020822"
                     /db_xref="UniProtKB/TrEMBL:F2RB77"
                     /locus_tag="SVEN_0918"
                     /old_locus_tag="SMD01683"
                     /product="possible chorismate mutase"
                     /protein_id="CCA54205.1"
                     /transl_table=11
                     /translation="MTEQNELQRLRAELDALDGTLLDTVRRRIDLGVRIARYKSRHGVP
                     MMQPGRVSLVKDRAARYAADHGLDESFLVNLYDVIITEMCRVEDLVMSRESLTAEDRR"
     gene            complement(6369..7355)
                     /locus_tag="SVEN_0919"
                     /old_locus_tag="SMD01684"
     CDS             complement(6369..7355)
                     /EC_number="1.3.1.-"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0919"
                     /db_xref="EnsemblGenomes-Tr:CCA54206"
                     /db_xref="GOA:F2RB78"
                     /db_xref="InterPro:IPR003099"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:F2RB78"
                     /locus_tag="SVEN_0919"
                     /old_locus_tag="SMD01684"
                     /product="4-amino, 4-deoxyprephenate dehydrogenase PapC"
                     /protein_id="CCA54206.1"
                     /transl_table=11
                     /translation="MSGFPRSVVVGGSGAVGGMFAGLLREAGSRTLVVDLVPPPGRPDA
                     CLVGDVTAPGPELAAALRDADLVLLAVHEDVALKAVAPVTRLMRPGALLADTLSVRTGM
                     AAELAAHAPGVQHVGLNPMFAPAAGMTGRPVAAVVTRDGPGVTALLRLVEGGGGRPVRL
                     TAEEHDRTTAATQALTHAVILSFGLALARLGVDVRALAATAPPPHQVLLALLARVLGGS
                     PEVYGDIQRSNPRAASARRALAEALRSFAALIGDDPDRAEDPDRADDPDRTDNPGHPGG
                     CDGAGNLDGVFEELRRLMGPELAAGQDHCQELFRTLHRTDDEGEKDR"
     gene            complement(7352..9412)
                     /locus_tag="SVEN_0920"
                     /old_locus_tag="SMD01686"
     CDS             complement(7352..9412)
                     /EC_number="2.6.1.85"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0920"
                     /db_xref="EnsemblGenomes-Tr:CCA54207"
                     /db_xref="GOA:F2RB79"
                     /db_xref="InterPro:IPR005801"
                     /db_xref="InterPro:IPR005802"
                     /db_xref="InterPro:IPR006221"
                     /db_xref="InterPro:IPR006805"
                     /db_xref="InterPro:IPR015890"
                     /db_xref="InterPro:IPR017926"
                     /db_xref="InterPro:IPR029062"
                     /db_xref="UniProtKB/TrEMBL:F2RB79"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 433.3; E-value:
                     2.3e-131)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SVEN_0920"
                     /old_locus_tag="SMD01686"
                     /product="Para-aminobenzoate synthase, amidotransferase
                     component or Para-aminobenzoate synthase, aminase
                     component"
                     /protein_id="CCA54207.1"
                     /transl_table=11
                     /translation="MRTLLIDNYDSFTHNLFQYIGEATGQPPVVVPNDADWSRLPLEDF
                     DAIVVSPGPGSPDRERDFGISRRAITDSGLPVLGVCLGHQGIAQLFGGTVGLAPEPMHG
                     RVSEVRHTGEDVFRGLPSPFTAVRYHSLAATDLPDELEPLAWSDDGVVMGLRHREKPLW
                     GVQFHPESIGSDFGREIMANFRDLALAHHRARRDAADSPYELHVRRVDVLPDAEEVRRG
                     CLPGEGATFWLDSSSVLEGASRFSFLGDDRGPLAEYLTYRVADGVVSVRGSDGTTTRTR
                     RPFFSYLEEQLERRRVPVAPDLPFEFNLGYVGYLGYELKAETTGDPAHRSPHPDAAFLF
                     ADRAIALDHQEGCCYLLALDRRGHDDGARAWLRETAETLTGLAVRVPAEPTPAMVFGVP
                     EAAAGFGPLARARHDKDAYLKRIDECLKEIRNGESYEICLTNMVTAPTEATALPLYSAL
                     RAISPVPYGALLEFPELSVLSASPERFLTIGADGGVESKPIKGTRPRGGTAEEDERLRA
                     DLAGREKDRAENLMIVDLVRNDLNSVCAIGSVHVPRLFEVETYAPVHQLVSTIRGRLRP
                     GTSTAACVRAAFPGGSMTGAPKKRTMEIIDRLEEGPRGVYSGALGWFALSGAADLSIVI
                     RTIVLADGRAEFGVGGAIVSLSDQEEEFTETVVKARAMVTALDGSAVAGAR"
     gene            complement(9556..11154)
                     /locus_tag="SVEN_0921"
                     /old_locus_tag="SMD01687"
     CDS             complement(9556..11154)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0921"
                     /db_xref="EnsemblGenomes-Tr:CCA54208"
                     /db_xref="GOA:F2RB80"
                     /db_xref="InterPro:IPR001279"
                     /db_xref="InterPro:IPR019204"
                     /db_xref="PDB:4JO0"
                     /db_xref="UniProtKB/TrEMBL:F2RB80"
                     /locus_tag="SVEN_0921"
                     /old_locus_tag="SMD01687"
                     /product="hypothetical protein"
                     /protein_id="CCA54208.1"
                     /transl_table=11
                     /translation="MRYSLRQDIAVEPVIAGWYGWSYLLPPQTLARFVHNRFNRIVESY
                     LDDPQVHAAAVRQRRMHGGPWIHAHEHRDAIEAWYRETAPRRERLDELFEAVRRLEEDI
                     LPRHHGECLDPVYQELPAALAGRVEVFYGRDNRTADYRFVEPLMYASEYYDESWQQVRF
                     RPVTEDAREFALTTPMLEYGPEQLLVDVPLNSPLLDAVFRGGLTGTELDDLAARFGLDG
                     ERAARFASYFEPTPAASEAPAPASSSEEDVLEYVGHACVFARHRGTTFLVDPVLSYSGY
                     PGGAENRFTFADLPERIDHLLITHNHQDHMLFETLLRIRHRVGRVLVPKSTNASLVDPG
                     LGGILRRLGFTDVVEVDDLETLSCGSAEVVALPFLGEHGDLRIRSKTGWLIRFGERSVL
                     FAADSTNISPTMYTKVAEVIGPVDTVFIGMESIGAAASWIYGPLYGEPLDRRTDQSRRL
                     NGSNFPQAREIVDALEPDEVYVYAMGLEPWMGVVMAVDYDESHPAIVDSDLLVRHVQDK
                     GGTAERLHLRRTLRL"
     misc_feature    complement(11140..11142)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11178..14069)
                     /locus_tag="SVEN_0922"
                     /old_locus_tag="SMD01688"
     CDS             complement(11178..14069)
                     /NRPS_PKS="Domain: AMP-binding (12-392). E-value: 1.2e-72.
                     Score: 236.5. Matches aSDomain:
                     nrpspksdomains_SVEN_0922_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (499-543). E-value: 1.5e-08.
                     Score: 27.0. Matches aSDomain:
                     nrpspksdomains_SVEN_0922_PP-binding.1"
                     /NRPS_PKS="Domain: TD (689-835). E-value: 5.1e-14. Score:
                     43.9. Matches aSDomain: nrpspksdomains_SVEN_0922_TD.1"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0922"
                     /db_xref="EnsemblGenomes-Tr:CCA54209"
                     /db_xref="GOA:F2RB81"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:F2RB81"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 271;
                     E-value: 2.7e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="SVEN_0922"
                     /old_locus_tag="SMD01688"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="CCA54209.1"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-74, bitscore:
                     240.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.5e-09, bitscore:
                     27.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVELPDLLTDLFRRHRGRTALRTAGRTWTYEELDRVTSALARRID
                     AECPAGRRVLVAGEHTAEAVVWALAAMRSHAVHTPMNPGLPADRFEEFARVADAALLVC
                     FEREALVRGEKAGLRALYAGDVGWPTDPAPAPADGTADEPARSRVAYSIFTSGSTGDPK
                     LVDVGHGGLLNLCRSLRRLLDITPDDQVLHFASLSFDASVSEILGTLYAGATLVVPVRD
                     QASWLGSVSRHLAAHGCDLAMLSPSVYARLDEAARSRIRKVEFCGEALGEGEYDKAARY
                     SRVFNAYGPTEATVCFSLAELTSYTPSIGTPVDGFRAYVRDPDSGDHATAGTGELVIVG
                     DGVALGYAGGSPAENEVFGTVDGSPAYATGDVVSLSDDGELTYLGRIDEQIKRLGHRVN
                     LAHVGSTLSRHLGREVALVRQDATILLVTAADGEATEESLMARIRDLVPVWEAPDRLVL
                     VDALPLTSGGKVDRSALRELLASPAGAPHGGTDGEDAAELRRVLDVVTAVLGQEIGPET
                     SIFDAGGSSLAMIQIQVKLSDAYGEEAVEAAFAAMDYDFAPAAFLRHLRGEAVAPAESA
                     VDTLLRRVETERDALRAELPLLRRDTRHEPVPGAADGDREVLLTGASGFIGGHVLDRLL
                     AAGRPVLVVSTGDPDGVLTGHATRFGRQAADYARVRAISYAELERWVDRRRGPVVDAVV
                     HCGYQVNHLLPLDSHLSGSVRNTALVVRAAAALGARSFAFLSAASAGADFLPLSAATLT
                     AVGDPYSRSKLISEEYVNTLAVLGCAVSHYRPGLVYGHRPEDRHHLKDDWFTALLETAR
                     RVGAMPRLSGHVPVCDVGTLADTLLGRPDANPGTADGASRTPDSRSAVVVHRTYALDEL
                     LRHTGLTEADVLAPAAWFERVRDGGEVPAPLLAAMQAALSGPGWPSAHREVDHDILGRL
                     LGTPPDTPAGDRPERTGTTAEAQNGAAHAPTPR"
     aSDomain        complement(11565..12002)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SVEN_0922_TD.1"
                     /evalue="5.10E-14"
                     /label="SVEN_0922_TD.1"
                     /locus_tag="SVEN_0922"
                     /protein_end="835"
                     /protein_start="689"
                     /score="43.9"
                     /tool="antismash"
                     /translation="VDAVVHCGYQVNHLLPLDSHLSGSVRNTALVVRAAAALGARSFAF
                     LSAASAGADFLPLSAATLTAVGDPYSRSKLISEEYVNTLAVLGCAVSHYRPGLVYGHRP
                     EDRHHLKDDWFTALLETARRVGAMPRLSGHVPVCDVGTLADT"
     aSModule        complement(11565..14033)
                     /complete
                     /domains="nrpspksdomains_SVEN_0922_AMP-binding.1"
                     /domains="nrpspksdomains_SVEN_0922_PP-binding.1"
                     /domains="nrpspksdomains_SVEN_0922_TD.1"
                     /final_module
                     /locus_tags="SVEN_0922"
                     /monomer_pairings="Tyr -> Tyr"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(12102..12137)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SVEN_0922_0006"
                     /evalue="2.30E+00"
                     /label="NRPS-A_a3"
                     /locus_tag="SVEN_0922"
                     /protein_end="656"
                     /protein_start="644"
                     /score="2.0"
                     /tool="antismash"
                     /translation="STGDPDGVLTGH"
     CDS_motif       complement(12333..12356)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SVEN_0922_0005"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a5"
                     /locus_tag="SVEN_0922"
                     /protein_end="579"
                     /protein_start="571"
                     /score="-3.2"
                     /tool="antismash"
                     /translation="PAESAVDT"
     aSDomain        complement(12441..12572)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SVEN_0922_PP-binding.1"
                     /evalue="1.50E-08"
                     /label="SVEN_0922_PP-binding.1"
                     /locus_tag="SVEN_0922"
                     /protein_end="543"
                     /protein_start="499"
                     /score="27.0"
                     /tool="antismash"
                     /translation="RVLDVVTAVLGQEIGPETSIFDAGGSSLAMIQIQVKLSDAYGEE"
     CDS_motif       complement(12861..12923)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SVEN_0922_0004"
                     /evalue="3.00E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="SVEN_0922"
                     /protein_end="403"
                     /protein_start="382"
                     /score="16.7"
                     /tool="antismash"
                     /translation="YLGRIDEQIKRLGHRVNLAHV"
     aSDomain        complement(12894..14033)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SVEN_0922_AMP-binding.1"
                     /evalue="1.20E-72"
                     /label="SVEN_0922_AMP-binding.1"
                     /locus_tag="SVEN_0922"
                     /protein_end="392"
                     /protein_start="12"
                     /score="236.5"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="RRHRGRTALRTAGRTWTYEELDRVTSALARRIDAECPAGRRVLVA
                     GEHTAEAVVWALAAMRSHAVHTPMNPGLPADRFEEFARVADAALLVCFEREALVRGEKA
                     GLRALYAGDVGWPTDPAPAPADGTADEPARSRVAYSIFTSGSTGDPKLVDVGHGGLLNL
                     CRSLRRLLDITPDDQVLHFASLSFDASVSEILGTLYAGATLVVPVRDQASWLGSVSRHL
                     AAHGCDLAMLSPSVYARLDEAARSRIRKVEFCGEALGEGEYDKAARYSRVFNAYGPTEA
                     TVCFSLAELTSYTPSIGTPVDGFRAYVRDPDSGDHATAGTGELVIVGDGVALGYAGGSP
                     AENEVFGTVDGSPAYATGDVVSLSDDGELTYLGRIDEQIK"
     CDS_motif       complement(13023..13073)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SVEN_0922_0003"
                     /evalue="1.60E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="SVEN_0922"
                     /protein_end="349"
                     /protein_start="332"
                     /score="14.2"
                     /tool="antismash"
                     /translation="TGELVIVGDGVALGYAG"
     CDS_motif       complement(13182..13208)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SVEN_0922_0002"
                     /evalue="8.00E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="SVEN_0922"
                     /protein_end="296"
                     /protein_start="287"
                     /score="9.0"
                     /tool="antismash"
                     /translation="YGPTEATVC"
     CDS_motif       complement(13563..13622)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SVEN_0922_0001"
                     /evalue="2.30E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="SVEN_0922"
                     /protein_end="169"
                     /protein_start="149"
                     /score="20.2"
                     /tool="antismash"
                     /translation="AYSIFTSGSTGDPKLVDVGH"
     gene            complement(14053..15231)
                     /locus_tag="SVEN_0923"
                     /old_locus_tag="SMD01689"
     CDS             complement(14053..15231)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0923"
                     /db_xref="EnsemblGenomes-Tr:CCA54210"
                     /db_xref="UniProtKB/TrEMBL:F2RB82"
                     /locus_tag="SVEN_0923"
                     /old_locus_tag="SMD01689"
                     /product="CmlG"
                     /protein_id="CCA54210.1"
                     /transl_table=11
                     /translation="MTAGSPGPAGRTPLRPRALAVRDIHSFLADLGMDCDVNPCTAFVG
                     TVEPGRVEDPAAWREFVARLGLTRALADLVEVAEEDVVVTLDPRPGPVEGGPAELADLV
                     TAYHNSRPLRIDEAVRLAYWRHTDGEYLVFVKFSHLIVDLADVVDLLRQIRAHLRGDTP
                     PGRIGSRYRHHARTVEQYTALPAADPAEVTRALGELPVPGRKGIPTISASVEEWLPLRE
                     GVTFDELLSAVTGVLLPALGGGLVLQYPYSRWEFATKGGYYVEIKPLVVRPGLPSDYTP
                     EYFAKTRHAQESLGRFTMSDLDAFARAFTSGRMPRVVVSDTTFMRPEPDRWRWVPVRSA
                     RVFEDLKFLADRSWPGPPLLRMQYKRGFLSPGAAADVLDGLKQRIGASGGTP"
     gene            complement(15228..16247)
                     /locus_tag="SVEN_0924"
                     /old_locus_tag="SMD01691"
     CDS             complement(15228..16247)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0924"
                     /db_xref="EnsemblGenomes-Tr:CCA54211"
                     /db_xref="InterPro:IPR025859"
                     /db_xref="UniProtKB/TrEMBL:F2RB83"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AurF"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SVEN_0924"
                     /old_locus_tag="SMD01691"
                     /product="hypothetical protein"
                     /protein_id="CCA54211.1"
                     /sec_met_domain="AurF (E-value: 6.3e-74, bitscore: 238.8,
                     seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDHTDEKSEAAGNDDGHVRIGGLPAFDPDDPAENAVINRLVGNW
                     HRRAAVKREEPDVYALFDPGRPDFREDMIPFRGHPIWERLSDETRSRLLSWGWVAYNRN
                     TVLIEQRIANPAFELVIGGAYPGLGGQQLELAVAQAMVDEQYHTLMHINGSAVTRRMRR
                     SDFSDRVLPDSHITTIHQEHLDRCEEPWQRSLTTLGFATVAEISINAYLDLLADDQEIQ
                     VVNSTTVKLHNRDEYCHASISGEMMKQVYEALPADRRRFLLEKVVAGLEAFVAPDFTTW
                     ESIVAFEGVPGWEKAAAEVREAQGGTHLVQDHSGIHTLLTEMDVLDQVEFGWGTTVTR"
     gene            16521..16847
                     /locus_tag="SVEN_0925"
                     /old_locus_tag="SMD01692"
     CDS             16521..16847
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0925"
                     /db_xref="EnsemblGenomes-Tr:CCA54212"
                     /db_xref="UniProtKB/TrEMBL:F2RB84"
                     /locus_tag="SVEN_0925"
                     /old_locus_tag="SMD01692"
                     /product="hypothetical protein"
                     /protein_id="CCA54212.1"
                     /transl_table=11
                     /translation="MLDGGLKVTERIQGVVVAALEEINLTREEKIPTDQVLDLCLYGDS
                     GVFESMYLVAFLSLVEENIEDEFGTEVSLTSEKAVSRRVSPFSSVRRLIGFIEEELELV
                     GVRG"
     gene            16865..17563
                     /locus_tag="SVEN_0926"
                     /old_locus_tag="SMD01694"
     CDS             16865..17563
                     /NRPS_PKS="Domain: PKS_KR (2-155). E-value: 5.1e-07. Score:
                     21.6. Matches aSDomain: nrpspksdomains_SVEN_0926_PKS_KR.1"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0926"
                     /db_xref="EnsemblGenomes-Tr:CCA54213"
                     /db_xref="GOA:F2RB85"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:F2RB85"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     153.1; E-value: 1.5e-46)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SVEN_0926"
                     /old_locus_tag="SMD01694"
                     /product="short-chain dehydrogenase or reductase SDR"
                     /protein_id="CCA54213.1"
                     /transl_table=11
                     /translation="MILMITGTRTGIGKALAEHFLEAGHDVVGCSRRPPTIDHPRYRHH
                     EADLADPGQTKRMFRSVRAEYGKLDALVNNAGTSSMNHFMTTPDEVSRKIFDINFFAVL
                     NCCREAVKLLRKSTEQSSAILNVSTVAVPWAIEGQLAYSASKSAVEQLVRVMSKELSTF
                     GIRVNGIGLPPVHTVLTRTVPRPKIDALIARQAISRQCTTADIVGPVEFLIGRQSEFIT
                     GETLFLGGVH"
     aSDomain        16871..17329
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SVEN_0926_PKS_KR.1"
                     /evalue="5.10E-07"
                     /label="SVEN_0926_PKS_KR.1"
                     /locus_tag="SVEN_0926"
                     /protein_end="155"
                     /protein_start="2"
                     /score="21.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LMITGTRTGIGKALAEHFLEAGHDVVGCSRRPPTIDHPRYRHHEA
                     DLADPGQTKRMFRSVRAEYGKLDALVNNAGTSSMNHFMTTPDEVSRKIFDINFFAVLNC
                     CREAVKLLRKSTEQSSAILNVSTVAVPWAIEGQLAYSASKSAVEQLVRV"
     gene            17563..19008
                     /locus_tag="SVEN_0927"
                     /old_locus_tag="SMD01696"
     CDS             17563..19008
                     /EC_number="6.2.1.3"
                     /NRPS_PKS="Domain: AMP-binding (10-384). E-value: 1.3e-59.
                     Score: 193.6. Matches aSDomain:
                     nrpspksdomains_SVEN_0927_AMP-binding.1"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0927"
                     /db_xref="EnsemblGenomes-Tr:CCA54214"
                     /db_xref="GOA:F2RB86"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR025110"
                     /db_xref="UniProtKB/TrEMBL:F2RB86"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     249.2; E-value: 1.1e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SVEN_0927"
                     /old_locus_tag="SMD01696"
                     /product="Long-chain-fatty-acid--CoA ligase"
                     /protein_id="CCA54214.1"
                     /sec_met_domain="AMP-binding (E-value: 9.9e-59, bitscore:
                     189.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDELLRRFEDFGARTALYDRGTAVTYAELLKRIGETRQLLALHG
                     VKPRETVVVHGDYSLDSVAALFALFLDRNVVVPVVTLTDTTLDTLVEHCRPGHLIRTTG
                     AGTEVEDLAARAEPAARAEPAGPAQLAGAEEPTDGAEAVHGRLGDPDAAGLVLLSSGST
                     GAPKVILHSLDVLVGEKLEKRPRRRENALNILMVLMFDHIGGINSLLSTLLVGGTAVLP
                     RQRTPDEICALIERHRILVLPTSPTYLNLIMVGDYHRTHDLSSLRLITYGTEPMSEELL
                     LRVRKTFPGVRLLQTFGTSETGIATTTSESSTSTYFKISDAGVEYRIVDGELQLRSRTQ
                     FLGYLNYDDDSLTEDRWFRTGDLVEEAAHGYLRIKGRAKEVINVGGEKLLPLELESVLM
                     GSPLVEDCVVYGRPNAITGQSVCVDIKPTGELTRAALRKHVTEFLAGRVEPFKVPSKIN
                     VVDTIAMSDRMKKLRSRPGADEE"
     aSDomain        17593..18714
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SVEN_0927_AMP-binding.1"
                     /evalue="1.30E-59"
                     /label="SVEN_0927_AMP-binding.1"
                     /locus_tag="SVEN_0927"
                     /protein_end="384"
                     /protein_start="10"
                     /score="193.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DFGARTALYDRGTAVTYAELLKRIGETRQLLALHGVKPRETVVVH
                     GDYSLDSVAALFALFLDRNVVVPVVTLTDTTLDTLVEHCRPGHLIRTTGAGTEVEDLAA
                     RAEPAARAEPAGPAQLAGAEEPTDGAEAVHGRLGDPDAAGLVLLSSGSTGAPKVILHSL
                     DVLVGEKLEKRPRRRENALNILMVLMFDHIGGINSLLSTLLVGGTAVLPRQRTPDEICA
                     LIERHRILVLPTSPTYLNLIMVGDYHRTHDLSSLRLITYGTEPMSEELLLRVRKTFPGV
                     RLLQTFGTSETGIATTTSESSTSTYFKISDAGVEYRIVDGELQLRSRTQFLGYLNYDDD
                     SLTEDRWFRTGDLVEEAAHGYLRIKGRAKEVINV"
     CDS_motif       18028..18075
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SVEN_0927_0001"
                     /evalue="3.20E-03"
                     /label="NRPS-A_a3"
                     /locus_tag="SVEN_0927"
                     /protein_end="171"
                     /protein_start="155"
                     /score="10.7"
                     /tool="antismash"
                     /translation="VLLSSGSTGAPKVILH"
     gene            19112..20827
                     /locus_tag="SVEN_0928"
                     /old_locus_tag="SMD01699"
     CDS             19112..20827
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0928"
                     /db_xref="EnsemblGenomes-Tr:CCA54215"
                     /db_xref="GOA:F2RB87"
                     /db_xref="InterPro:IPR003042"
                     /db_xref="InterPro:IPR006905"
                     /db_xref="UniProtKB/TrEMBL:F2RB87"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 439.9; E-value: 1.9e-133)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SVEN_0928"
                     /old_locus_tag="SMD01699"
                     /product="FAD-binding protein"
                     /protein_id="CCA54215.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.2e-10, bitscore:
                     28.5, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Trp_halogenase (E-value: 9.1e-34,
                     bitscore: 107.1, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSKVAIIGGGPAGSVAGLTLHKLGHDVTIYERSAFPRYRVGES
                     LLPGTMSILNRLGLQEKIDAQNYVKKPSATFLWGQDQAPWTFSFAAPKVAPWVFDHAVQ
                     VKREEFDKLLLDEARSRGITVHEETPVTDVDLSDPDRVVLTVRRGGESVTVESDFVIDA
                     GGSGGPISRKLGVRQYDEFYRNFAVWSYFKLKDPFEGDLKGTTYSITFEDGWVWMIPIK
                     DDLYSVGLVVDRSKSAEVREQGADAFYSSTLAKCAKAMDILGGAEQVDEVRIVQDWSYD
                     TEVFSADRFFLCGDAACFTDPLFSQGVHLASQSAVSAAAAIDRITRHGDEKDAVHAWYN
                     RTYREAYEQYHQFLASFYTFASFTEPDSEFWRKRRITESDDDRLTRKKWFESLAGNGPE
                     DPSGTVASFRDRASTMIAIGRHQRPELSDDFSEAELNPARVRWISDLTKRLNSITRFKW
                     TGGKAVLKQHYRVEPIGFRLEQREVLANGEGLDMAQYPMDDEARQIFQDLAEEEFGYKT
                     LVKRLGAVGRQELSTQIVVRLMEAGLLTGYDAQGEKVFVQGRLHFGGVGVEYEV"
     gap             20961..20980
                     /estimated_length=20
     gene            21026..22006
                     /locus_tag="SVEN_0929"
                     /old_locus_tag="SMD01700"
     CDS             21026..22006
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SVEN_0929"
                     /db_xref="EnsemblGenomes-Tr:CCA54216"
                     /db_xref="InterPro:IPR001395"
                     /db_xref="InterPro:IPR023210"
                     /db_xref="UniProtKB/TrEMBL:F2RB88"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     340.2; E-value: 1.6e-103)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SVEN_0929"
                     /old_locus_tag="SMD01700"
                     /product="Aldo-keto reductase"
                     /protein_id="CCA54216.1"
                     /transl_table=11
                     /translation="MRHTRLRDLEVSRIGLGTMGMSFGYTGSGSDDAGSVRALHRALDL
                     GVTFLDTAEIYGPYTNERLVGRALGARRDQVVLATKFGLVSHAGGGPGQLDSSPANVRT
                     AVEGSLRRLGTDHIDLCYQHRVDPGTPIEDTVGALAELVAEGKIRHIGLSEAGPATIRR
                     AHAVHPVTAVQSEYSLWTRDPEEAVLPVLRELGIGFVAYSPLGHGFLTGTVRAAGRFDA
                     SDLRADNPRFTAENLPRNLRIADEIAAVAAEADATPAQVALAWLLTRGDDVVPIPGSRR
                     AARVEENTTAAEVRLSAGQLARLDALPPAAGEHHTEEQMAMMDRV"
ORIGIN
        1 atgtccacga tttcggatct acgacaggcg tcgaccttcg acatcgacat ccacaccctg
       61 ctgccggccg actcgccgcg cttcgcgctc gaccaggcgc acgtacgggc gctcgcggag
      121 agcgagaccg agttcccccc gatcctggtg caccgggcga ccctgcgggt catcgacggc
      181 atgcaccggg tgcgggccgc gaagctgcgc aacagggaca ccatcggcgc gcgctggttc
      241 gagggcgacg agcaggcggc cttcctgctc gccgtggagt ccaacacgcg gcacgggctc
      301 ccgctctcca gcgacgagcg gaaacaggcg gcgctgcgga tattacgtac ccacccccac
      361 tggtccgacc gcagcatcgc cgagcggacc ggctggagcg ccaccggcgt cggcgccctg
      421 cgccgggaca tcgccgaccc ggacgcgcgg ccggaggcgc gggtggggcg ggacggccgg
      481 gtccgcccgt ccaccacggc cgagggccgc cgggtggcgg ccgaggtgat ccggcggaat
      541 ccggacgcct ctctgcggga gatcgcccgg caggccggga tctccgtggg caccgcccgc
      601 gacgtgcgcc accggctggc cgaggggcgg ccggcggttc ccgacggtcg ccgtgccgac
      661 gctccccccg ccgatcccgt cgccgcgccg ccggggccgg ggccggacga ggaccgtacg
      721 gggcgagggg gcgcgcccga cctcgcccgc cgcatcaccc tcttcgacgg gctccgcaac
      781 gatccctcgc tccggctcag cgagagcgga cggctggtcc tgcagcgcct gcacgcgcag
      841 ctgcggacca ccgaggagtg gaagcgcctc gccccgacca tccccctgca cggccggagc
      901 gcggtggccg acatcctgtc cgcctgcgcg gacgacctca aggggatggc cagggaactg
      961 cggtgcgtcg aggactccct gaccgaccac gccgcgtccg gaagcgagcg gcggccggac
     1021 gcgggcccgg cctgatcccc taccgccgcc ccgccgtagc ggcggcgccc gctcccccca
     1081 aggcggcggc cgccacccgg tgggccacgg cggtgacgac caggcggcgg ccgacccgcc
     1141 atcggccgtg gagggtgtgg agtggtcgcc cctcgtcgtc gtggccggtg cggaggagac
     1201 gggcgcggaa ggtctgccgg tacgggtcga ggaccagctc ggcctcgcgg aagtccagcc
     1261 aggtcccggt cagcgggaac cacgccttgt acaccgactc cttggcgctg aagaacagcc
     1321 ggtcccagtg gagcgcgggc agggcccggg acagttcggt caggtgggcc cgctcggtgg
     1381 gtgacgcgat ccgccggagc aggcccggcg gcagcggtgc gtggggttcg gcgtcgatgc
     1441 cgagggcggc gacgtcgatc ctgcgggaca cagcggccgc gcggtagccg tcgcagtggg
     1501 tcatcgaacc caccacgccc tccggccagc tcggcgcgcc ccgctcgccc ggcaccatcg
     1561 gcccggcggg ccggccgagg gaggtcaggg cgagccgtgc gcagtgccgt acggtggcga
     1621 actcccggcg ccggcggtcc gccgcccggt gcagcacggc cgcctcctcc gggaagatcc
     1681 aggcgtccgg gacgtccccg aactcctcgg cggtcagcgc cgcttccggt acgagcccgg
     1741 tcaggagcgt cggcgtcacc gcttcgcccc cgacggcttc ccgccgccgg cgcgggcggc
     1801 ctgggggcgc ggcaccgcgg cctcccattc ggcggccagc tcccgcaggt ccgcgtcgac
     1861 catctggcgc gggtacgccc agcgcagcag gggcgcggtc atggcggtgg tgacgagggc
     1921 catgacgacc atcagggagt acaggtccgt gtcgaggagc cccagttgca ggccgacgcc
     1981 gaggatgatg agttcggtga gaccgcgggt gttcatgagg atgcccagtg tcgtcgccga
     2041 ccgtccgggc ctgcccgcgg cccgcgctcc caggtaggcg ccgccgaact tgccgccgac
     2101 cgccacgagg aggatcaggc cgagctcgcc gagtccgtcc gcgtcgaccg tgctcaggtc
     2161 caccttcagc ccggcgacgg tgaagtaggc gggcagcagc atccaggtga ccgcctcgaa
     2221 ccggtcggcg accgccgcgc gcagccgctc ggtgccctgg cgcggcacga tcgcgcccgc
     2281 gaggaacgcg ccgaagatga agtgcagtcc gaaccactcg ctcagcgcgc cggagacgag
     2341 cagcagcacc gtgagaaccc cgagcggccc ggcccccggc ccgcgctcgc ccgcccccgg
     2401 ccggtccgtg ccctgctcac ccccggccac gccctgcccg cgcccggcca cgccccgttc
     2461 tcccccggcc acgccccgcc cgtgcccgcc cgcacccgtt ccgcccggct cgcgggcggt
     2521 caggtacctg ccgaggagcg gccgtaccac cgcgaccatg gccacggcgt acggcaggac
     2581 gaggagcacc tgccaggagc tctggctgcc cgtgaaggtg aggacggccg cgagcagcag
     2641 ccaggcgacg acgtcaccgg cggccgcgct cgccatggcc agcgcgccga cccgcgtgtg
     2701 ctgaatgccc cggtcggtga ggatgcgggc gaggaccggg aaggccgtga tggacatggc
     2761 cgcgccgagg aacagcacga agccgagccg gtcgccgacc gggtgggcgt tccacagcca
     2821 caccgccagc acggcgccga gtccgaacga gcagacgatc gatcccacgg acaccccgac
     2881 cgcggcgcgc ttgttcccgc gcagcagccg gtggtcgagt tcgaggccga cgaggaacat
     2941 gaacagcgcg acgccgaggt ttcccagggt gctgagcatt ggccggacgt ccgtggggaa
     3001 aacggcgtcc gagagggcgc cgtggaacag cgtcggaccg agcaggatgc cggcgaggat
     3061 ctcgccgagg acggccggct ggccgcatcg ccgtgcgagg cgcccgagca cgtgcgccag
     3121 tgcgaggacc accgcgagcc ccatcatgat catggctgtc tggtgggtcg tcatgaacac
     3181 tccttctccg cgccgggggt gtccaagtcg ttagacacgg cgttccgggc gttgctatgt
     3241 tgagaggtat gtcgagtcct gaggcggaaa gaagcgagcc accggtgatc cggtggctga
     3301 tcgcgtaacc ctctgacgac cctgcttccc ccggcctctg ccgccgagca gcgcgtcgcg
     3361 cattcgccac ggatcaaccg catcgcggga tcacgtccgg atctctccgg gacgtctccc
     3421 acgccacgca cggcctttcg tcctgcgtcg cgtctcccct ttctgcgatg tagttggagc
     3481 tttttcatgc cattcgccat ctacgttctc gggctggccg tattcgccca gggaacgtcg
     3541 gaattcatgc tgtccgggct cgtggaggac atggccgccg atttcggcgt gtccctccag
     3601 gccgtcggct cactcacctc ggccttcgcg gtcggaatga tcatcggcgc accgctggtc
     3661 gcgatgctga gcctgcgctg gccgcgccgc cgggcgctgc tcgcgttcct catcacgttc
     3721 ctcctcgcgc acgtcgtcgg cgctctcacc aacagcttcg aagtcctctt cgtcacgcgg
     3781 gtgatcgccg cactggccaa cgcgggcttc ctcgccgtcg gcctcgccac cgcggcgagc
     3841 atggccgggc cgcaggcgaa gggccgggcg acgtcgatcc tgctcagcgg cgtcaccctc
     3901 gcctgcatcg ccggtgtccc gctcggcgcc gtcctcagcg aggtctgggg ctggcgctcg
     3961 gcgttctggg gggtcgcgat catctccgcc cccgcggtct tcgcggtgct gtggtccgtg
     4021 ccggcgacgc ccgtcgaccc ctcggctccc agcgtccgcc acgaactgcg ggcgctccgc
     4081 acgcccaagg tgggcgtgac gctgctgctc ggggcgctgg tcaacggcgc gacgttctgc
     4141 tcgttcacgt acctcgcgcc ggtcatcacc aacgtgacgg agctgagctc cggttgggtg
     4201 ccggccacgc tcgcgctgtt cggcattggt tccttcgtcg gggtcaacgt cggcggccgg
     4261 ctcgcggaca cccgtcccgg ccaggtcctc gcggtcggtg gtgcggccct cctcgccggc
     4321 tggctggtgt tcgccctcac ggccgggaac ccggtcgtgg cgctcgtcct cgtcttcgtc
     4381 cagggcgcgc tgtcgttcgg cgtgggctcc acgctgatcg cgcaggccct ctacacggcg
     4441 tcggacgccc ccacgctcgc cggtggcttc gccaccgccg cgctgaacgt cggcgccgcc
     4501 gccgggcccg ccctgggcgg tctcgccctg ggcgccgagt tcggttaccg ctcgccgctg
     4561 gtggtgagcg ccgtgctcgt cgcgaccgcg ctcgtcctgg cgggcgtggc ccgggccgcc
     4621 ggtgtcaccg gcgccaaggc cgacgccgcc gccacggaga acccgcccac cgggcgtccg
     4681 gtggaggccc gttcctgact gtccgtacgg tcggtccttc ccgtccgtcc cgtctccggt
     4741 ggcccgtccc cctcgtgggg gcgggccacc ggccgtccgg ggtggacggc acgggagccg
     4801 gtcagagcag ggagaggaaa tgggtgacca tgtccgccga ctgctcgggg ttcagccggg
     4861 ggtcgcaggt ggaccggtag tccgtgaacc gcggcggccg gtcgagctcc gacacgcatt
     4921 cggtgaccgg gtccggggtg agctccaggt ggaggcccgc gggccactgc ccgtgctccc
     4981 ggagcgtccg tacgaaggcg gcggtctcgg cgcgcatcgg ctcgatcagc cgggtcttgt
     5041 gaccggccag tttcagcccg ttgccgtgca tcgggtcgca gagccagacg accggtgcgc
     5101 cgtgccgggc gaccgcacgg acgaccggcg gcaggagctc gtccacctcc ttggcgccga
     5161 agcgcacgat gaacgtcagc cgtcccggta cgccctccgg gttcagcgac cggctcaggg
     5221 cgaccgcgtc ctccggcgac accgtcggcc ccagcttgac gcctacgggg ttgtgtacgg
     5281 cctgggcgag ggcgacgtgg gcgccgtcct cccggcgggt gcgctcgccg atccagccga
     5341 aatgcgcgga accgctgtac gtaccgtggg cgccctcgcg caccagcggc cgctcgtacg
     5401 gcagcagcag caactcgtgc gaggtgtaga cccgttccag gacgggccgg cccgaccagg
     5461 agcgccggat ctcgtcgagg acgatctgcg agcaggtgta cgcggtgagg agcctgcggg
     5521 gttccggggt cctggcggcc ggttcgaact cgggctcgtt gacggcgtcg ccgcagtagc
     5581 tgggcatctt ccggcccgcg cccgactcct cggtctcgaa cggcgaggag cgcggcttcc
     5641 cgtactggcc ggcgatccgg ccgagggcca ccgcgggcag cccgctgccg gcccgcatga
     5701 tcgcggcgag gccctggagg ttgtcgacct tgcgccggac caggtcgggc acggcctcgt
     5761 ggaagcgttc ggcgcagtcg ccgccctgga cgaggagcgc cgcgccgcgg gcgaccagcg
     5821 ccatcccgtt catcaggtcg acgacctcgt cctcgggggt gaggacgggc agtccggcca
     5881 gctcccgctc caccgtgtcg acggcgtccg ggtcgggcca gtagggctgt tgtgccgccg
     5941 tccgcccggt cagggccgcg agcgtcgtgg tcgcgtgcat cgtggtctcc tccgccctcg
     6001 tcggaacacc gccggcgggg ctgtggtggg ggtcgtacgg agtggtccgg accggcgggg
     6061 tcaccgccgg tcctcggccg tcaggctctc ccggctcatc accaggtcct cgacgcggca
     6121 catctccgtg atgatcacgt cgtagaggtt caccaggaac gattcgtcga ggccgtggtc
     6181 ggcggcgtag cgggcggccc tgtccttgac caggctgacc cggccgggct gcatcatcgg
     6241 gacgccgtgc cgggacttgt accgcgcgat gcggacaccg aggtcgatgc ggcgccgcac
     6301 cgtgtccaga agcgtcccgt cgagggcgtc gagctccgcg cgcagccgct gcagctcgtt
     6361 ctgctcggtc atcggtcctt ctcgccttcg tcgtcggtgc ggtggagggt gcggaacagc
     6421 tcctggcagt ggtcctggcc cgccgcgagc tccggtccca tgagccggcg gagttcctcg
     6481 aagacgccgt cgaggttccc ggcgccgtcg catcccccgg gatggccggg gttgtcggtg
     6541 cggtcggggt cgtcggcgcg gtccgggtcc tcggcgcggt ccgggtcgtc gccgatcagc
     6601 gcggcgaagg agcgcagggc ctcggcgagc gcccggcgcg cggacgccgc ccgggggttg
     6661 gaccgctgga tgtccccgta cacctcgggg ctgccgccga gcacacgggc caggagggcg
     6721 agcagcacct ggtggggcgg cggtgccgtc gccgccaggg cccggacgtc gacgccgagg
     6781 cgggcgaggg cgagcccgaa ggagaggatc acggcgtgcg tcagggcctg ggtcgccgcc
     6841 gtcgtccggt cgtgctcctc cgccgtgagc cgtacgggcc tgccgccgcc gccctcgacg
     6901 agccgcagca gggccgtgac gcccggcccg tccctggtga ccacggcggc cacgggccgg
     6961 ccggtcatgc cggcggcggg ggcgaacatc gggttgaggc ccacgtgctg gacgccgggg
     7021 gcgtgggccg cgagctccgc ggccatgccc gtccggacgg acagggtgtc ggcgagcagc
     7081 gcgcccggtc gcatgagccg ggtcacgggc gccacggcct tgagggccac gtcctcgtgt
     7141 acggcgagca ggacgaggtc cgcgtcccgg agggcggccg cgagctcggg ccccggcgcg
     7201 gtgacgtcgc ccaccaggca ggcgtccggc cgtcccggcg gcggtacgag gtcgacgacg
     7261 agcgtgcggc tgcccgcctc ccgcagcagc ccggcgaaca tgccgcccac cgctccgctg
     7321 ccgccgacga cgacgctccg ggggaagccg ctcatcgggc gcccgccact gcgctgccgt
     7381 cgagggcggt gaccatggcg cgggccttga ccacggtctc ggtgaactcc tcctcctggt
     7441 cggagaggga cacgatcgcc ccgccgacgc cgaactcggc ccggccgtcg gccagcacga
     7501 tggtgcggat gacgatgctg aggtcggcgg cgccgctgag ggcgaaccat ccgagcgccc
     7561 cggagtagac gccccggggg ccttcctcca ggcggtcgat gatctccatg gtgcgcttct
     7621 tgggcgcgcc ggtcatggag ccgccgggga aggcggcgcg tacgcaggcg gcggtgctgg
     7681 tgccgggccg cagccgtccc cggatggtcg acaccagctg gtgcacgggc gcgtaggtct
     7741 ccacctcgaa gagccggggc acgtggacgg agccgatcgc gcagacgctg ttgaggtcgt
     7801 tgcggaccag gtcgacgatc atcaggttct cggcccggtc cttctcccgg ccggccaggt
     7861 cggcgcggag ccgctcgtcc tcctccgcgg tgccgccccg ggggcgggtc cccttgatgg
     7921 gcttggactc gacgccgccg tcggcgccga tcgtgaggaa ccgctcgggc gaggcgctga
     7981 gcaccgacag ctcggggaac tcgagcaggg cgccgtacgg gacggggctg atggcgcgca
     8041 gcgcggagta gagcggcagg gccgtcgcct cggtcggcgc ggtgaccatg ttggtcaggc
     8101 agatctcgta cgactcgccg ttgcggatct ccttgaggca ctcgtcgatg cgcttgaggt
     8161 aggcgtcctt gtcgtggcgt gcgcgggcca gggggccgaa gccggccgcc gcctcgggga
     8221 ccccgaagac catggcgggg gtcggctcgg ccgggacgcg gacggccagg ccggtgaggg
     8281 tctcggccgt ctcccgcagc caggcgcggg cgccgtcgtc gtggccccgg cggtcgaggg
     8341 ccagcaggta gcagcagcct tcctggtggt cgagggcgat ggcgcggtcg gcgaagagga
     8401 acgcggcgtc ggggtgcggg gaccggtgcg cggggtcgcc ggtggtctcc gccttcagct
     8461 cgtagccgag gtagccgacg tagccgaggt tgaactcgaa gggcaggtcg ggggcgacgg
     8521 ggacccgccg gcgttcgagc tgctcctcca ggtagctgaa gaagggtcgc cgcgtccggg
     8581 tcgtggtgcc gtcggagccg cggacggaga cgacgccgtc ggcgacgcgg taggtgaggt
     8641 actcggcgag cgggccgcgg tcgtcgccga ggaaggagaa gcgcgaggcg ccttcgagga
     8701 cggagctgct gtccagccag aacgtggcgc cctcgccggg caggcagccg cggcgtacct
     8761 cttcggcgtc cggcagcacg tcgacgcggc gcacgtggag ttcgtacggg gagtcggccg
     8821 cgtcgcgacg tgcccggtgg tgggcgaggg cgaggtcgcg gaagttggcc atgatctccc
     8881 ggccgaagtc gctgccgatg gactccgggt ggaactggac gccccacagc ggcttctcgc
     8941 ggtgccgcag gcccatgacg acgccgtcgt cgctccaggc gaggggttcg agctcgtcgg
     9001 ggaggtcggt ggcggccagg gagtggtagc gcacggcggt gaacggcgag gggaggcccc
     9061 ggaagacgtc ctcgccggtg tgccgcacct cggagacccg gccgtgcatg ggttccgggg
     9121 cgaggccgac ggttccgccg aagagctggg cgatgccctg gtggccgagg cagacgccga
     9181 ggacgggcag gccgctgtcg gtgatcgccc ggcggctgat cccgaagtcc cgttcccggt
     9241 cggggctgcc ggggcccggg gacacgacga tcgcgtcgaa gtcctcgagg ggcagccgcg
     9301 accagtcggc gtcgttgggc acgacgacgg ggggctgccc ggtggcctcg ccgatgtact
     9361 ggaacaggtt gtgggtgaac gagtcgtagt tgtcgatcag aagcgtgcgc atgatggggc
     9421 accttgtctc gaagggctcg ccggagggcg cgggggcggc ggcgggccac ggggacgggc
     9481 cggaggggcc gtgccggagg ggccgggggc cgggggcggc ggatcgccgc gccccggccg
     9541 cgggcgtcgc gtcgctcaga ggcgcagcgt ccgccggagg tgcagccgtt cggcggtccc
     9601 gcccttgtcc tggacgtgcc ggacgaggag gtcgctgtcg acgatggcgg ggtggctctc
     9661 gtcgtagtcg acggccatca cgacgcccat ccagggttcg aggcccatcg cgtacacata
     9721 gacctcgtcg ggctccaggg cgtcgacgat ctccctcgcc tgggggaagt tggagccgtt
     9781 gagccgtcgg ctctggtcgg tcctgcggtc gagcggctcg ccgtagagcg gaccgtagat
     9841 ccagctggcc gccgcgccga tgctctccat gccgatgaag acggtgtcga cggggccgat
     9901 cacctcggcc accttggtgt acatcgtcgg ggagatgttg gtggagtcgg cggcgaacag
     9961 cacggagcgc tccccgaagc ggatcagcca tccggtcttg ctgcggatgc gcaggtcgcc
    10021 gtgttcgccg aggaagggca gggcgacgac ctcggcggat ccgcaggaca gcgtctccag
    10081 gtcgtcgacc tcgacgacgt cggtgaagcc gagccggcgc aggatgccgc cgagtccggg
    10141 gtccaccagg cttgcgttgg tggatttggg gaccaggacc ctgccgaccc ggtgccggat
    10201 ccgcagcagg gtctcgaaca gcatgtggtc ctggtggttg tgggtgatga gcaggtggtc
    10261 gatgcgctcg ggcaggtcgg cgaaggtgaa ccggttctcc gctcccccgg ggtatccgct
    10321 gtagctcagc accgggtcca cgaggaaggt ggtgccccgg tggcgggcga acacgcaggc
    10381 gtggccgacg tattcgagga cgtcctcctc ggaggaggag gcgggggcgg gagcttccga
    10441 cgccgccggg gtgggctcga agtacgaggc gaaccgggcg gcccgctcgc cgtcgaggcc
    10501 gaaccgcgcc gccaggtcgt cgagttcggt cccggtcagg ccgccgcgga agaccgcgtc
    10561 gagcagcggg gagttcagcg ggacgtcgac caggagctgc tccgggccgt actccagcat
    10621 cggcgtggtg agggcgaact cgcgggcgtc ctccgtgacg gggcggaagc ggacctgctg
    10681 ccaggactcg tcgtagtact cggaggcgta catcagcggc tcgacgaagc ggtagtcggc
    10741 cgtgcggttg tccctgccgt agaacacctc cacccggccg gccagggccg ccggcagctc
    10801 ctggtagacg gggtcgaggc actcgccgtg gtggcggggc aggatgtcct cctccaggcg
    10861 ccggacggcc tcgaagagtt cgtcgagccg ctcgcgccgt ggagcggtct cccggtacca
    10921 ggcctcgatg gcgtcgcggt gctcgtgggc gtggatccag gggccgccgt gcatccggcg
    10981 ctgccggacg gccgccgcgt ggacctgcgg gtcgtcgagg tagctctcga cgatgcggtt
    11041 gaagcggttg tggacgaagc gggcgagggt ctgcggcggc agcaggtacg accagccgta
    11101 ccagccggcg atgaccggct cgaccgcgat gtcctggcgt aacgagtagc gcatggggga
    11161 ctacggctcc gttcctgtca gcgcggtgtc ggcgcgtggg cggcgccgtt ctgggcctct
    11221 gcggtggtcc cggtccgctc cggccggtcg ccggccgggg tgtccggcgg ggtgccgagc
    11281 agccggccga ggatgtcgtg gtcgacctcg cggtgggcgg agggccagcc cggtccgctc
    11341 agggccgcct gcatggcggc caggagcggg gcggggacct cgccgccgtc gcgtacccgc
    11401 tcgaaccatg cggcgggcgc caggacgtcc gcctcggtga ggccggtgtg gcgcagcagc
    11461 tcgtcgagcg cgtacgtacg gtggacgacg accgccgaac gggagtccgg agtccgggag
    11521 gcgccgtcgg ccgtgcccgg gttcgcgtcc ggccggccga ggagggtgtc ggccagggtg
    11581 ccgacgtcgc agacgggcac gtggccgctg agccggggca tcgcgcccac ccggcgcgcg
    11641 gtctccagga gggcggtgaa ccagtcgtcc ttgaggtggt ggcggtcctc gggccggtgc
    11701 ccgtagacaa gacccggccg gtagtgggag acggcgcagc ccagcacggc gagggtgttc
    11761 acgtactcct cgctgatcag cttcgaccgc gagtacgggt cgccgaccgc cgtgagggtc
    11821 gcggccgaca ggggcaggaa gtccgccccg gccgaggcgg ccgacaggaa cgcgaaggac
    11881 cgggcgccga gggccgccgc cgcgcggacg accagggccg tgttgcgcac gctgccgctc
    11941 aggtggctgt cgagcggcag caggtggttg acctggtagc cgcagtggac caccgcgtcg
    12001 acgacggggc cgcgccgccg gtcgacccag cgctcgagct ccgcgtacga gatggcccgg
    12061 acccgggcgt agtcggcggc ctgccgtccg aaccgggtcg cgtggccggt gaggaccccg
    12121 tcggggtcgc cggtgctgac gacgaggacg gggcggccgg cggcgagcag ccggtcgagg
    12181 acgtgcccgc cgatgaagcc ggacgcgccg gtgaggagca cctcgcggtc gccgtccgcg
    12241 gcgccgggca ccggctcgtg gcgggtgtcg cggcgcagca gcggcagctc ggcgcgcagg
    12301 gcgtcgcgct cggtctccac ccggcgcagc agcgtgtcga cggcggactc cgccggggcg
    12361 acggcctcgc cgcgcaggtg gcgcaggaag gcggccgggg cgaagtcgta gtccatggcg
    12421 gcgaacgcgg cctcgacggc ctcctcgccg tacgcgtcgg agagtttgac ctggatctgg
    12481 atcatggcga gggagctgcc gccggcgtcg aagatggacg tctcggggcc gatctcctgg
    12541 ccgaggacgg cggtcacgac gtcgagcacg cgccgcagtt ccgcggcgtc ctcgccgtcc
    12601 gtcccgccgt gcggggcgcc ggccggggag gcgagcagct cgcgcagggc gctccggtcc
    12661 accttcccgc cggaggtgag cgggagcgcg tcgaccagga ccaaccggtc gggtgcctcc
    12721 cagacgggca ccaggtccct gatccgggcc atcagcgact cctcggtggc ctcgccgtcc
    12781 gcggccgtga cgagcaggat cgtggcgtcc tggcggacga gtgccacctc gcgccccagg
    12841 tggcgggaga gcgtggagcc gacgtgggcg aggttcaccc ggtggccgag gcgtttgatc
    12901 tgctcgtcga tccgtccgag gtaggtgagt tcgccgtcgt cggagaggga gacgacgtcc
    12961 ccggtggcgt aggccgggga gccgtcgacc gtaccgaaca cctcgttctc ggccgggctg
    13021 ccgccggcgt agccgagtgc cacgccgtcg ccgacgatga cgagttcgcc ggtgcccgcc
    13081 gtggcgtggt caccggagtc ggggtcgcgg acgtaggccc ggaagccgtc gacgggggtg
    13141 ccgatgctcg gcgtgtacga ggtcagctcg gccagggaga agcagacggt ggcttcggtc
    13201 gggccgtacg cgttgaacac cctgctgtac cgggcggcct tgtcgtactc gccctcgccg
    13261 agggcctcgc cgcagaactc caccttccgg atgcggctgc gggccgcctc gtcgagccgg
    13321 gcgtagacgg acggcgacag catggcgagg tcacagccgt gggcggcgag gtgccgcgag
    13381 acggacccca gccaggaggc ctggtcgcgc acggggacga cgagggtcgc cccggcgtac
    13441 agggtgccga ggatctcgct gacggaggcg tcgaacgaca gcgacgcgaa gtgcaggacc
    13501 tggtcgtcgg gggtgatgtc gagcagcctc cgcagggagc ggcagaggtt gagcaggccg
    13561 ccgtgcccga cgtcgacgag cttggggtcg ccggtcgaac ccgaggtgaa gatggagtac
    13621 gcgacgcggg aacgggccgg ctcgtcggcc gtgccgtccg ccggcgccgg ggccgggtcg
    13681 gtgggccagc cgacatcacc ggcgtacagg gcgcgcaggc cggccttctc gccgcgcacc
    13741 agcgcctcgc gctcgaagca gacgagcagc gccgcgtccg cgacccgcgc gaactcctcg
    13801 aaccggtcgg cgggcaggcc cgggttcatc ggggtgtgca cggcgtggct gcgcatcgcc
    13861 gcgagggccc agaccacggc ttccgccgtg tgctccccgg cgaccaggac gcggcggccc
    13921 gcggggcact cggcgtcgat ccggcgggcg agcgcgctgg tgacccggtc gagctcctcg
    13981 taggtccagg tccgtccggc ggtccgcagc gcggtccgtc cgcggtggcg ccggaagagg
    14041 tcggtcaaca ggtcagggag ttccaccact tgctccaatt cgctgcttga gtccgtcgag
    14101 gacgtcggcc gcggccccgg gggagaggaa gccgcgcttg tactgcatcc gcaacagcgg
    14161 cgggcccggc caggaccggt cggcgaggaa cttgaggtcc tcgaagaccc gggcgctgcg
    14221 caccgggacc cagcgccacc ggtccggctc cggacgcatg aacgtcgtgt cggagacgac
    14281 gacacggggc atccggccgc tggtgaacgc ccgcgcgaag gcgtcgaggt cggacatcgt
    14341 gaaccggccg agggactcct gggcgtgccg ggtcttggcg aagtactcgg gggtgtagtc
    14401 ggacggcagc ccgggccgta cgacgagggg cttgatctcg acgtagtagc cgcccttcgt
    14461 cgcgaactcc cagcgggagt aggggtactg caggaccagg ccgccgccga gggcgggcag
    14521 caggacgccg gtgacggcgc tgagcagttc gtcgaaggtg acgccctcgc gcagcggcag
    14581 ccactcctcc acggacgcgg agatcgtcgg gatgcccttg cggcccggca cgggcagctc
    14641 gccgagggcg cgggtgacct ccgcggggtc ggccgccggc agggccgtgt actgctcgac
    14701 ggtccgtgcg tggtggcggt agcgggagcc gatccggccg ggcggggtgt cgccgcgcag
    14761 atgggccctg atctgccgga gcaggtcgac gacgtcggcg aggtcgacga tcagatgact
    14821 gaacttgacg aagacgaggt actcgccgtc cgtgtgccgc cagtacgcga ggcgcacggc
    14881 ctcgtcgatc cgcagcggcc ggctgttgtg gtacgcggtg acgaggtccg ccagctcggc
    14941 ggggccgccc tcgacggggc ccggccgcgg gtcgagggtg acgaccacgt cctcctccgc
    15001 cacctcgacc aggtcggcca gggcccgggt gaggccgagc cgggccacga actcccgcca
    15061 cgcggccggg tcctcgaccc ggccgggttc gacggtgccc acgaaggccg tgcacgggtt
    15121 gacgtcgcag tccatgccga ggtcggcgag gaagctgtgg atgtcgcgca cggcgagcgc
    15181 gcgggggcgc agcggagtgc ggccggccgg cccggggctg cccgcggtca tcgggtcacc
    15241 gtcgtgcccc agccgaactc gacctggtcg aggacgtcca tctcggtgag gagggtgtgg
    15301 atgcccgagt ggtcctgcac gaggtgggtg ccgccctggg cctcgcgcac ctcggcggcg
    15361 gccttctccc agccggggac gccctcgaac gcgacgatcg actcccaggt cgtgaagtcg
    15421 ggggcgacga aggcctccag gccggccacg accttctcca ggaggaatcg gcgccggtcg
    15481 gccggaaggg cctcgtagac ctgcttcatc atctcgccgg agatcgaggc gtggcagtac
    15541 tcgtcgcggt tgtgcagctt caccgtggtg gagttgacga cctggatctc ctggtcgtcg
    15601 gcgaggaggt cgaggtaggc gttgatggag atctcggcga ccgtcgcgaa gcccagggtg
    15661 gtgaggctcc gctgccacgg ttcctcgcag cggtccaggt gttcctggtg gatcgtggtg
    15721 atgtgcgagt ccggcagcac gcggtcggag aagtcgctcc ggcgcatccg ccgggtcacc
    15781 gcgctgccgt tgatgtgcat gagcgtgtgg tactgctcgt ccaccatggc ctgtgcgacg
    15841 gcgagctcca gctgctggcc gccgagaccg gggtacgcgc cgccgatgac cagttcgaag
    15901 gccgggttgg cgatccgctg ctcgatcagc accgtgttgc ggttgtaggc gacccagccc
    15961 cagctcagca gccgggaacg ggtctcgtcg gagaggcgct cccagatcgg gtggccccgg
    16021 aaggggatca tgtcctcccg gaagtccggg cggccgggat cgaacagcgc gtagacgtcc
    16081 ggttcctcgc gcttcacggc ggcgcgccgg tgccagttcc cgacgagccg gttgatgacc
    16141 gcgttctcgg cggggtcgtc cgggtcgaat gccggcagtc cgccgatccg gacgtgcccg
    16201 tcgtcgttcc cggcggcttc ggatttctcg tccgtgtggt cacgcatggc ccaccccttc
    16261 cttcacttcc ctttgcgggc tcttcccttt gcgggctcgg cccttcccgg gtccggcgtc
    16321 tcgaagtctg tggatatcgg tcgcgggccg caagggtgtg cagatcacca ccccgtgcaa
    16381 ctgaaggaac cggacagttg aacagggcgg tgaaccgcgc ggactgaacg accttgcgtg
    16441 ggccgggggc gtatgacata aaaatccagg cgtcggcccg gagcacgact cggccggcga
    16501 cgcgatctgt tctgtctttc gtgctggacg gaggccttaa ggtgacggag cgaatccagg
    16561 gtgtcgtcgt ggcggcgctc gaagaaatca atctgacgcg tgaggagaag attccgaccg
    16621 accaggtcct cgacctgtgt ctctacggtg actccggcgt gttcgagtcc atgtacctgg
    16681 tggccttcct ctccctggtc gaggagaaca tcgaggacga gttcggcacc gaggtgtcgc
    16741 tcacgtccga gaaggcggtg tcccgccggg tgagtccgtt cagcagcgtg cgcaggctga
    16801 tcggcttcat cgaggaagag ctggaactcg tcggcgtgcg cggttagcgc aggtcaccgc
    16861 cgccatgatc ctcatgatca ccggcacccg gaccggcatc ggcaaggccc tcgcggagca
    16921 tttcctggag gccgggcacg acgtcgtcgg gtgcagcaga aggcccccga ccatcgacca
    16981 cccgcgctac cggcaccacg aggcggatct cgcggacccc ggtcagacga aacgcatgtt
    17041 ccggagcgtc cgggcggagt acggaaagct cgacgccctg gtgaacaacg ccggcacctc
    17101 gtcgatgaac catttcatga cgaccccgga cgaggtttcc cggaagatat tcgacatcaa
    17161 tttcttcgcc gtgctgaact gctgccggga agcggtcaaa ctgctgcgga aatccactga
    17221 gcagagttcc gcgatcctga acgtctccac ggtcgcggtg ccctgggcca tcgaaggaca
    17281 gctcgcctat tcggccagca agagcgcggt cgaacaactc gtccgcgtga tgagcaagga
    17341 gttgtccacg ttcgggatca gggtgaacgg aatcggactt ccgcccgttc acaccgtatt
    17401 gacgaggacc gttccccggc caaagatcga cgctctgatc gcacgccagg cgatatcccg
    17461 tcagtgcacg acggcggaca tcgtcggccc cgtggagttc ctgatcggcc ggcagtcgga
    17521 gttcatcacg ggcgagacgc tctttctagg gggtgtgcac tgatgcgcga cgaactgctg
    17581 cgaaggttcg aggacttcgg cgcccgtacg gcgctctacg accgcgggac cgccgtcacg
    17641 tacgcggaac tcctgaagcg gatcggcgag acccggcagc tgctggcgct ccacggcgtg
    17701 aagccgcggg agaccgtggt cgtccacggc gactactcgc tggactcggt ggcggccctt
    17761 ttcgccctct tcctcgaccg gaacgtcgtg gtgccggtgg tcacgctcac cgacaccacc
    17821 ctcgacaccc tcgtcgagca ctgccggccg ggccatctga tcaggacgac cggggcgggt
    17881 acggaggtcg aggacctcgc cgcacgggcc gaacccgccg cacgggccga acccgccgga
    17941 ccggcccagc tcgccggcgc cgaggaaccc accgacgggg ccgaggccgt gcacggccgg
    18001 ctcggcgacc ctgacgcggc cggactcgtg ctgctcagca gcggcagcac cggcgcgccc
    18061 aaggtcatcc tgcacagtct cgacgtgctc gtcggcgaga agctggagaa gcggccgcgc
    18121 cgccgggaga acgccctcaa catcctcatg gtgctgatgt tcgatcacat cgggggcatc
    18181 aactccctgc tcagcaccct cctggtcggg ggcaccgcgg tcctcccccg ccagcgcacc
    18241 ccggacgaga tctgcgcgct gatcgagcgc caccggatcc tcgtcctccc caccagcccg
    18301 acctatctca acctgatcat ggtcggcgac taccaccgca cacacgacct cagcagcctg
    18361 cgcctgatca cgtacggcac cgagccgatg tccgaggaac tcctcctgcg ggtccgcaag
    18421 accttcccgg gggtccggct gctccagacc ttcgggacga gcgagaccgg catcgccacc
    18481 accaccagcg aatcgtcgac cagcacgtac ttcaagatct ccgacgccgg tgtggagtac
    18541 cgcatcgtcg acggcgaact ccagctcagg agccggaccc agttcctcgg ctatctgaac
    18601 tacgacgacg actcgctgac cgaggaccgc tggttccgga ccggggacct ggtcgaggag
    18661 gcggcccacg gctacctccg gatcaagggc cgggccaagg aggtcatcaa cgtcggcggc
    18721 gagaagctcc tcccgctgga actcgaatcg gtcctcatgg gcagccccct cgtcgaggac
    18781 tgcgtcgtgt acggcaggcc gaacgcgatc accggccagt ccgtgtgcgt cgacatcaag
    18841 cccacaggcg aactcacccg cgcggccctc cgcaagcacg tgacggagtt cctcgccggc
    18901 cgggtcgagc cgttcaaggt cccctcgaag atcaacgtgg tcgacacgat cgcgatgtcg
    18961 gaccgcatga agaagctgcg gtcccggccg ggcgccgacg aggagtgaac ggcctcctcc
    19021 cgcccgtacc ccgcacccct ttcacagcgc ttcctcctcg ccgccccggc gcggagtccc
    19081 gtcagcctgt ccccgtccca aggagtacgt gatgacacga tcgaaggtgg cgatcatcgg
    19141 cggagggccg gccggtagtg tcgcgggcct caccctgcac aagctgggcc acgacgtcac
    19201 gatctacgag cggtccgcct tcccccggta ccgcgtcggc gagtccctgc tgcccggcac
    19261 gatgtcgatc ctcaaccgcc tcgggctgca ggagaagatc gacgcgcaga actacgtcaa
    19321 gaagccctcg gcgaccttcc tctggggcca ggaccaggcc ccgtggacgt tctccttcgc
    19381 ggcccccaag gtcgcgccct gggtcttcga ccacgccgtc caggtgaagc gcgaggaatt
    19441 cgacaagctc ctcctcgacg aggcccggag ccgcgggata accgtccacg aggagacccc
    19501 ggtcaccgac gtggacctgt ccgaccccga ccgcgtcgtc ctgaccgtgc gccggggcgg
    19561 cgagagcgtc accgtcgaga gcgacttcgt catcgacgcg ggcggctcgg gcggtccgat
    19621 ctcccgcaag ctcggcgtgc gccagtacga cgagttctac cggaacttcg cggtctggtc
    19681 gtacttcaag ctgaaggacc ccttcgaggg ggacctcaag ggcaccacgt actcgatcac
    19741 cttcgaggac ggctgggtct ggatgatccc catcaaggac gacctgtaca gcgtcggcct
    19801 cgtcgtcgac cgctcgaagt ccgccgaggt gcgcgagcag ggcgccgacg ccttctactc
    19861 gtccaccctc gccaagtgcg ccaaggccat ggacatcctc ggcggcgccg agcaggtcga
    19921 cgaggtccgg atcgtgcagg actggtccta cgacaccgag gtcttctccg ccgaccgctt
    19981 cttcctctgc ggagacgccg cctgcttcac cgacccgctg ttctcccagg gcgtgcacct
    20041 ggcctcgcag tcggcggtct cggccgccgc ggccatcgac cgcatcaccc ggcacgggga
    20101 cgagaaggac gcggtgcacg cctggtacaa ccgcacctac cgcgaggcct acgagcagta
    20161 ccaccagttc ctcgcctcct tctacacctt cgcctccttc acggagcccg actccgagtt
    20221 ctggcggaag cggcgcatca cggagtccga cgacgaccgg ctgacccgaa agaagtggtt
    20281 cgagagcctg gcgggcaacg gcccggagga cccctccggg accgtggcgt ccttccgcga
    20341 ccgggcatcc acgatgatcg cgatcggccg ccaccagcgt ccggaactca gcgacgactt
    20401 cagcgaggcc gagctgaacc cggcccgggt ccgctggatc agcgacctca ccaagcggct
    20461 gaacagcatc acccgcttca agtggaccgg cggcaaggcc gtgctcaagc agcactaccg
    20521 cgtcgagccg atcggcttcc ggctggaaca gcgcgaggtc ctcgccaacg gggaagggct
    20581 cgacatggcc cagtacccga tggacgacga ggcccggcag atcttccagg acctcgccga
    20641 ggaggagttc ggctacaaga cgctggtcaa gcgcctcggc gcggtcggcc ggcaggagct
    20701 gagcacccag atcgtcgtcc ggctgatgga ggcgggcctc ctcaccggct acgacgcgca
    20761 gggcgagaag gtcttcgtcc agggccggct ccacttcggc ggcgtcgggg tcgagtacga
    20821 ggtctgaccg ccgccgcacg accacccgcc gggcagcccc gtcccgttca cgggagcgga
    20881 cgggacgggc cccggcgggc tcgggggccg gtgcacccac cggccaccac ccaccggcca
    20941 ccgcccaccg gccaccgggc nnnnnnnnnn nnnnnnnnnn acccccaccc ctcatccacc
    21001 ctcgcgcccc gaaggaggcg gtccgatgcg gcacacgaga ttgcgggacc tggaggtctc
    21061 ccggatcggc ctggggacca tgggcatgtc cttcggctac acgggctccg gctcggacga
    21121 cgcgggctcc gtccgcgccc tgcaccgcgc cctcgacctc ggcgtcacct tcctcgacac
    21181 cgccgagatc tacgggccct acaccaacga acggctcgtc ggccgagcgc tcggcgcccg
    21241 ccgcgaccag gtggtgctcg ccacgaagtt cggcctcgtc tcgcacgcgg gcggcggccc
    21301 cggacagctc gacagcagcc ccgcgaacgt ccgtaccgcc gtggagggtt cgctgcggcg
    21361 gctcgggacc gaccacatcg acctctgcta ccagcaccgc gtcgaccccg gcacccccat
    21421 cgaggacacc gtcggcgccc tcgccgagct ggtcgccgag ggcaagatcc gccacatcgg
    21481 cctctccgag gcgggccccg ccacgatccg ccgcgcgcac gccgtccacc cggtcaccgc
    21541 ggtccagtcc gagtactccc tgtggacccg cgaccccgag gaggcggtcc tgccggtcct
    21601 gcgcgaactg ggcatcggct tcgtggcgta ctccccgctc ggccacggct tcctcaccgg
    21661 cacggtccgc gcggccggcc gcttcgacgc ctcggacctc cgggcggaca acccccgctt
    21721 caccgcggag aacctgcccc ggaacctgcg catcgccgac gagatcgccg ccgtcgccgc
    21781 cgaggcggac gccaccccgg cgcaggtcgc cctcgcctgg ctgctcaccc ggggggacga
    21841 cgtcgtgccg attcccggca gccggcgggc cgcccgcgtc gaggagaaca cgacggccgc
    21901 cgaggtccgc ctgagcgcgg ggcaactcgc ccgcctcgac gccctgcccc ccgccgcggg
    21961 cgagcaccac actgaggagc agatggcgat gatggaccgc gtgtag
//
