BGC0000898: desosamine biosynthetic gene cluster from Streptomyces venezuelae
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Location: 1 - 12,441 nt. (total: 12,441 nt).
This entry is originally from NCBI GenBank AF079762.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000898
Short description desosamine biosynthetic gene cluster from Streptomyces venezuelae
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • saccharide (hybrid/tailoring)
Loci
AF079762.1
via
Compounds
  • desosamine
  • pikromycin
  • neomethymycin
  • narbomycin
Species Streptomyces venezuelae [taxonomy]
References
Chemical products information
desosamine Evidence:
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C25H43N1O7
Chemical database entries
PubCHEM
NPAtlas
pikromycin Evidence:
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C28H47N1O8
neomethymycin Evidence:
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C25H43N1O7
narbomycin Evidence:
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C28H47N1O7
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAC68676.1
  • desVIII
 119 - 1327 (+) putative tautomerase
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    • AAC68677.1
    • desVII
    		 1475 - 2755 (+) glycosyl transferase
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      • AAC68678.1
      • desVI
      		 2845 - 3558 (+) N,N-dimethyltransferase
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        • AAC68679.1
        • desR
        		 3625 - 6054 (+) beta-glucosidase
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          • AAC68680.1
          • desV
          		 6143 - 7282 (-) transaminase
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            • AAC68681.1
            • desIV
            		 7279 - 8292 (-) TDP-glucose-4,6-dehydratase
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              • AAC68682.1
              • desIII
              		 8424 - 9302 (-) alpha-D-glucose-1-phosphate thymidylyltransferase
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                • AAC68683.1
                • desII
                		 9495 - 10952 (-) putative reductase
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                  • AAC68684.1
                  • desI
                  		 10949 - 12196 (-) 4-dehydrase
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                    Biosynthesis information
                    Annotation changelog

                    Entry version: 4

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-10-07
                    Update chemical activity to schema version 2.11
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 3

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-09-15
                    Update compound structure (SMILES) for desosamine
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2022-09-15
                    Linked new PubChem id for desosamine (pubchem:5282034)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2022-09-15
                    Linked new NPAtlas id for desosamine (npatlas:NPA01238)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2022-09-15
                    Add new compound: pikromycin
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2022-09-15
                    Add new compound: neomethymycin
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2022-09-15
                    Add new compound: narbomycin
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 2

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2019-10-16
                    Migrated from v1.4
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 1

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2015-06-12
                    Submitted
                    • (ID: RIBLHRV4YSJAGJ5EVZV4GS2Z)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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