LOCUS       BGC0000899             17665 bp    DNA     linear   BCT 24-JUL-2016
DEFINITION  Streptomyces narbonensis desosamine biosynthetic gene cluster,
            partial sequence.
ACCESSION   BGC0000899
VERSION     BGC0000899
KEYWORDS    .
SOURCE      Streptomyces narbonensis
  ORGANISM  Streptomyces narbonensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 14:23:50
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17665
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            <1..528
                     /gene="nbmA"
     CDS             <1..528
                     /NRPS_PKS="Domain: Thioesterase (3-156). E-value: 2.2e-23.
                     Score: 75.7. Matches aSDomain:
                     nrpspksdomains_nbmA_Thioesterase.1"
                     /codon_start=1
                     /gene="nbmA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /note="terminal thioesterase I (TEI) domain of type I
                     polyketide synthase"
                     /product="NbmA"
                     /protein_id="AAM88350.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 9.1e-10, bitscore:
                     29.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLRAAGDAPVVLLGHSGGALLAHELAFRLERAHGTAPAGIVLVD
                     PYPPGHQEPIEVWSRQLGEGLFAGELEPMSDARLLAMGRYARFLAGPRPGRSSAPVLLV
                     RASERLGDWPEERGDWRAHWDLPHSVADVPGDHFTMMRDHAPAVAVAVLAWLDGIERDT
                     AAGRRTAQGADQ"
     source          1..17665
                     /db_xref="taxon:67333"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces narbonensis"
     subregion       1..17665
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="saccharide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..17665
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     aSDomain        10..468
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nbmA_Thioesterase.1"
                     /evalue="2.20E-23"
                     /label="nbmA_Thioesterase.1"
                     /locus_tag="nbmA"
                     /protein_end="156"
                     /protein_start="3"
                     /score="75.7"
                     /tool="antismash"
                     /translation="RAAGDAPVVLLGHSGGALLAHELAFRLERAHGTAPAGIVLVDPYP
                     PGHQEPIEVWSRQLGEGLFAGELEPMSDARLLAMGRYARFLAGPRPGRSSAPVLLVRAS
                     ERLGDWPEERGDWRAHWDLPHSVADVPGDHFTMMRDHAPAVAVAVLAWL"
     CDS_motif       22..90
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_nbmA_0001"
                     /evalue="1.10E-06"
                     /label="NRPS-te1"
                     /locus_tag="nbmA"
                     /protein_end="30"
                     /protein_start="7"
                     /score="21.2"
                     /tool="antismash"
                     /translation="DAPVVLLGHSGGALLAHELAFRL"
     gene            525..1370
                     /gene="nbmB"
     CDS             525..1370
                     /NRPS_PKS="Domain: Thioesterase (25-251). E-value: 4e-57.
                     Score: 186.1. Matches aSDomain:
                     nrpspksdomains_nbmB_Thioesterase.1"
                     /codon_start=1
                     /gene="nbmB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 268.9; E-value: 4.8e-82)"
                     /gene_kind="biosynthetic-additional"
                     /note="thioesterase II (TEII)"
                     /product="NbmB"
                     /protein_id="AAM88351.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1e-11, bitscore:
                     35.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDRVLNVDSSLWIRRFHPSPNSAVRLVCLPHAGGSASYFFRFSE
                     ELHPSVEALSVQYPGRQDRRAEPCLESVEELAEHVVAATEAWWREGRLAFFGHSLGASV
                     AYEAARILEQRHGVRPEGLYVSGRRAPSLAPDRLVHQLDDRAFLAEIRQLSGTDERFLQ
                     DDELMRLVLPALRSDYKAAETYEHRPSAKLACPVMALAGDRDPKAPLNEVAEWRRHTSG
                     PFCLRAYSGGHFYLNDQWHGICNDISDHLLVTRGAPDSRVVQPPTRLIEGAAKRWQNPR
                     "
     aSDomain        600..1277
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nbmB_Thioesterase.1"
                     /evalue="4.00E-57"
                     /label="nbmB_Thioesterase.1"
                     /locus_tag="nbmB"
                     /protein_end="251"
                     /protein_start="25"
                     /score="186.1"
                     /tool="antismash"
                     /translation="RLVCLPHAGGSASYFFRFSEELHPSVEALSVQYPGRQDRRAEPCL
                     ESVEELAEHVVAATEAWWREGRLAFFGHSLGASVAYEAARILEQRHGVRPEGLYVSGRR
                     APSLAPDRLVHQLDDRAFLAEIRQLSGTDERFLQDDELMRLVLPALRSDYKAAETYEHR
                     PSAKLACPVMALAGDRDPKAPLNEVAEWRRHTSGPFCLRAYSGGHFYLNDQWHGICNDI
                     SDHL"
     CDS_motif       792..860
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_nbmB_0001"
                     /evalue="1.40E-06"
                     /label="NRPS-te1"
                     /locus_tag="nbmB"
                     /protein_end="112"
                     /protein_start="89"
                     /score="20.8"
                     /tool="antismash"
                     /translation="EGRLAFFGHSLGASVAYEAARIL"
     gene            1367..2713
                     /gene="nbmC"
     CDS             1367..2713
                     /codon_start=1
                     /gene="nbmC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 141.1; E-value: 7.7e-43)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative NDP-deoxyhexose 3,4-isomerase"
                     /product="NbmC"
                     /protein_id="AAM88352.1"
                     /sec_met_domain="p450 (E-value: 5.1e-15, bitscore: 44.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDPARALTQPPLGRTVSAVADPELGAHLLETRGIHWIHAANGD
                     PYAAVLRGQADDPYPAYERVRARGVLSFSPTGSWVTADHAVAASVLCSTEFGVPGADGV
                     PVPQQVLSYGEGCPLEHEQAPRAAAEVPGAWAGQRRAVVEEVHRQILEGLAPDPSASYA
                     FELVGGFVRPAVTGAAAAVLGVPAGRRGEFAELVERLRPLSDSLLAPQSLRTVRAADGA
                     LAALTALLAEAGVSAATDGSDPSSGPSAPSSDPSASSSGPTAPSSGPTAPSSGVAGRPD
                     GALLSALGVTAAVQLTGNAVLALLAHPEQWRELCARPGLAAAAVEETLRYDPPVQLDAR
                     VARVETELAGRRLPAGAHVVVLTAGTGRDPGVFTDPERFDLARPDATAHLALHPAGPYG
                     PVASLVRLQAEVALRTLAGRFPGLRKAGPVLRPRRAPVGRGPLSVPVGS"
     gene            2782..4062
                     /gene="nbmD"
     CDS             2782..4062
                     /codon_start=1
                     /gene="nbmD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 367.4;
                     E-value: 1.8e-111)"
                     /gene_kind="biosynthetic-additional"
                     /note="desosaminyl transferase"
                     /product="NbmD"
                     /protein_id="AAM88353.1"
                     /sec_met_domain="MGT (E-value: 1.6e-145, bitscore: 474.9,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLLTSFAHHTHYYGLVPLAWALLAAGHEVRVASQPALTDTITG
                     SGLAAVPVGTDHLIHEYRVRMAGEPRPNHPAIAFDEARSEPLDWDHALGIDAILAPYFY
                     LLANNDSMIDDLVGFARSWQPDLVLWEPTTYAGAVAAQVTGAAHARVLWGPDVMGSARR
                     KFVALRDRQPPEHREDPTAEWLTWTLDRFGASFEEELLTGQFTVDPTPPSLRLDTGLPT
                     VGVQYVPYNGTSVVPDWLAEPPARPRVCLTLGVSAREVLGGDGVSQADILEALADLDIE
                     LVATLDAGQRAEIRSYPKHTRFTDFVPMHALLPSCSAIVHHGGAGTYATAVINAVPQVM
                     LAELWDAPVKARAVAEQGAGFFLPPAGLTPQAVRDAVVRILDDPSVLAAAHRLREETHR
                     DPTPAGIVPELERLAAQHRRPPADARR"
     gene            4151..4864
                     /gene="nbmE"
     CDS             4151..4864
                     /codon_start=1
                     /gene="nbmE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 232.7; E-value:
                     7.6e-71)"
                     /gene_kind="biosynthetic-additional"
                     /note="N,N-methyltransferase"
                     /product="NbmE"
                     /protein_id="AAM88354.1"
                     /transl_table=11
                     /translation="MYEVDHADVYDLFYLGRGKDYAAEASDIADLVRTRTPEASSLLDV
                     ACGTGTHLEHFTKEFGDTAGLELSEDMLTHARKRLPDATLHQGDMRDFRLGRRFSAVVS
                     MFSSVGYLRTTAELDAAVASFAAHLEPGGVVVVEPWWFPETFADGWVSADVVRRDGRTV
                     ARVSHSVRDGDATRMEVHFTVADPGRGVRHFSDVHLITLFHRAEYEAAFTAAGLRVEYL
                     EGGPSGRGLFVGVPA"
     gene            4908..7424
                     /gene="nbmF"
     CDS             4908..7424
                     /codon_start=1
                     /gene="nbmF"
                     /note="beta glucosidase"
                     /product="NbmF"
                     /protein_id="AAM88355.1"
                     /transl_table=11
                     /translation="MHQAQREKSTVTGKTRIPRVRRSRTTPRAFTLAVVGTLLAGTTVA
                     AAAPGAAGTGHVQYTSKAAELVAQMTLDEKISFVHWALDPDRQNVGYLPGVPRLGIPEL
                     RAADGPNGIRLVGRTATALPAPVALASTFDDSMADSYGRVMGRDGRALGQDMVLGPMMN
                     NIRVPHGGRNYETFSEDPLVSSRTAVAQIKGIQGAGLMTTAKHFAANNQENNRFSVNAT
                     VDEQTLREIEFPAFEASSKAGAASFMCAYNGVNGKPSCGNDELLNNVLRTQWGFQGWVM
                     SDWLATPGTDAITKGLDQEMGVELPGDIPPGEPSPPAKFFGDALKQAVLNGTVPEAAVT
                     RSAERIVNQMDKFGLLLATPAPRPERDKAGAQAVSRKVAENGAVLLRNEGQALPLAGDA
                     GKSIAVIGPTAVDPKVTGLGSAHVVPDSAAAPLDTIKARAGAGATVTYETGEETFGTRI
                     PAAQLSPAFNQGHQLEPGKAGALYDGTLTVPADGEYRISVKATGGYATVQLGSHTIEAG
                     QVYGKVSSPLLKLTKGTHKLTISGFAMSATPLSLELGWVTPEAADATIAKAVESARKAR
                     TAIVFAYDDGTEGVDRPNLSLPGTQDKLISAVADANPNTIVVLNTGSSVLMPWLSKTRA
                     VLDMWYPGQAGAEATAALLYGDVNPSGKLTQSFPAAENQHAVAGDPNRYPGVDNQQTYS
                     EGIHVGYRWFDKENVKPLFPFGHGLSYTSFTQSAPTVVRTSTGGLKVTVTVRNSGQRAG
                     QEVVQAYLGASPKVTAPQAEKKLVGYTKVALAAGESKTVTVNVDRRQLQYWDAASDSWR
                     TGTGSRLLQTGSSSADLKNSSQVTVW"
     gene            complement(7514..8653)
                     /gene="nbmG"
     CDS             complement(7514..8653)
                     /NRPS_PKS="Domain: Aminotran_1_2 (44-220). E-value:
                     1.9e-08. Score: 25.7. Matches aSDomain:
                     nrpspksdomains_nbmG_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="nbmG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     395.7; E-value: 3.5e-120)"
                     /gene_kind="biosynthetic-additional"
                     /note="aminotransferase"
                     /product="NbmG"
                     /protein_id="AAM88356.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 6.5e-128,
                     bitscore: 416.7, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.3e-09, bitscore:
                     25.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARTETGRVPFLDLKAAYEELRPETDAAIARVLDSGRYLLGPEL
                     EAFEAEFATYCETDHAVGVNSGMDALQLALRGLGIGPGDEVIVPSHTYIASWLAVSATG
                     ATPVPVEPNEDHPTLDPLLVEKAITPRTRALLPVHLYGHPADLDALRDLADRHGLHIVE
                     DAAQAHGARYRGRRIGAGASVAAFSFYPGKNLGCFGDGGAVVTGDPALAERLRMLRNYG
                     SRQKYSHETKGTNSRLDEIQAAVLRIRLAHLDSWNGRRSTLAAEYLSGLAGLPGIALPV
                     TAPGTDPVWHLFTVRTDRRDELRDHLDSRGVDTLTHYPVPVHLSPAYAGQAPPEGSLPR
                     AESFARQVLSLPIGPHLERTQALRVIDAVREWAEQAGRP"
     aSDomain        complement(7994..8521)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nbmG_Aminotran_1_2.1"
                     /evalue="1.90E-08"
                     /label="nbmG_Aminotran_1_2.1"
                     /locus_tag="nbmG"
                     /protein_end="220"
                     /protein_start="44"
                     /score="25.7"
                     /tool="antismash"
                     /translation="LEAFEAEFATYCETDHAVGVNSGMDALQLALRGLGIGPGDEVIVP
                     SHTYIASWLAVSATGATPVPVEPNEDHPTLDPLLVEKAITPRTRALLPVHLYGHPADLD
                     ALRDLADRHGLHIVEDAAQAHGARYRGRRIGAGASVAAFSFYPGKNLGCFGDGGAVVTG
                     DPALAERLRMLRN"
     gene            complement(8650..9684)
                     /gene="nbmH"
     CDS             complement(8650..9684)
                     /NRPS_PKS="Domain: NAD_binding_4 (4-180). E-value: 1.6e-18.
                     Score: 58.6. Matches aSDomain:
                     nrpspksdomains_nbmH_NAD_binding_4.1"
                     /codon_start=1
                     /gene="nbmH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     335.3; E-value: 6.4e-102)"
                     /gene_kind="biosynthetic-additional"
                     /note="NDP-glucose 4,6 dehydratase"
                     /product="NbmH"
                     /protein_id="AAM88357.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 6.3e-20, bitscore:
                     61.1, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.1e-18,
                     bitscore: 57.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 3.6e-19, bitscore:
                     58.6, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLLVTGGAGFIGSHFVRQLLAGAYPDVPAGEVIVLDSLTYAGNR
                     ANLAPVEADPRLRFVHGDIRDADLLARELRGVDAVVHFAAESHVDRSIAGASVFTGTNV
                     QGTQTLLQCALDAGVGRVVHVSTDEVYGSIDSGSWNESSPLEPNSPYAASKAGSDLVAR
                     AYHRTYGLDVRITRCCNNYGPYQHPEKLIPLFVTNLLDGGTLPLYGDGANVREWVHTDD
                     HCRGIALVLAGGRAGEVYHIGGGRELTNRELTGILLDSLGADWSSVRRVADRQGHDLRY
                     SLDGGKIERELGYRPQIAFADGLARTIRWYRENRDWWEPLKATAPQPPATAPQPPATAV
                     GVSA"
     aSDomain        complement(9145..9672)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nbmH_NAD_binding_4.1"
                     /evalue="1.60E-18"
                     /label="nbmH_NAD_binding_4.1"
                     /locus_tag="nbmH"
                     /protein_end="180"
                     /protein_start="4"
                     /score="58.6"
                     /tool="antismash"
                     /translation="VTGGAGFIGSHFVRQLLAGAYPDVPAGEVIVLDSLTYAGNRANLA
                     PVEADPRLRFVHGDIRDADLLARELRGVDAVVHFAAESHVDRSIAGASVFTGTNVQGTQ
                     TLLQCALDAGVGRVVHVSTDEVYGSIDSGSWNESSPLEPNSPYAASKAGSDLVARAYHR
                     TYGLDVRITRCCN"
     CDS_motif       complement(9613..9675)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_nbmH_0001"
                     /evalue="4.40E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="nbmH"
                     /protein_end="24"
                     /protein_start="3"
                     /score="9.7"
                     /tool="antismash"
                     /translation="LVTGGAGFIGSHFVRQLLAGA"
     gene            complement(9759..10637)
                     /gene="nbmI"
     CDS             complement(9759..10637)
                     /codon_start=1
                     /gene="nbmI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 279; E-value:
                     7.2e-85)"
                     /gene_kind="biosynthetic-additional"
                     /note="NDP-glucose synthase"
                     /product="NbmI"
                     /protein_id="AAM88358.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.6e-12, bitscore:
                     37.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLHPATSVISKQILPVYNKPMIYYPLSVLMLGG
                     IREIQIISTPQHIELFQSLLGNGRHLGIELDYAVQKEPAGIADALLVGAGHIGDDTCAL
                     ILGDNIFHGPGLYSLLRDSIARLDGCVLFGYPVKDPERYGVAEVDATGRLTGLVEKPEK
                     PRSHLAVTGLYLYDNDVVDIAKNIRPSPRGELEITDVNRVYLERGRAELVDLGRGFAWL
                     DTGTHDSLLRAAQYVQVLEERQGVWIAGLEEIAFRMGFIDAEACHSLGEGLSRTEYGSY
                     LMEIAGREGAP"
     gene            complement(10840..12297)
                     /gene="nbmJ"
     CDS             complement(10840..12297)
                     /codon_start=1
                     /gene="nbmJ"
                     /note="putative NDP-deoxyhexose 3,4-reductase"
                     /product="NbmJ"
                     /protein_id="AAM88359.1"
                     /transl_table=11
                     /translation="MTAPAPVATAPSARCAHPGADLGAAVRAVGQSLAAGGLVPSDEAG
                     STARHLVGLAVRYGNSPFTPLEEARHDLGVDRDAFRRLLALFPRVPELRAAVEGGPAGA
                     YWQNTLLPLERRGVFDSALAGKPVFPYSVGLYPGPTCMFRCHFCVRVTGARYDPSALDT
                     GNAMFRSVIDEIPAGNPHALYFSGGLEPLTNPGLGTLAAHAAEHGLRPTVYTNSFALTE
                     RTLERQPGLWGLHAVRTSLYGLNDEEYEQTTGKKAAFRRVRENLRRFQQLRAEREAPIN
                     LGFAYIVLPGRAHRLLDLVDFIADLDESGQGRTIDFVNIREDYSGREDGKLPQEERAEL
                     QEALAAFEERVRERTPGLHIDYGYALNSLKAGADAELLRIKPATMRPTAHPQVAVQVDL
                     LGDVYLYREAGFPDLDGATRYIAGRVGPGTSLTEVVRDYVERGGRVAARDGDEYFMDGF
                     DQVVTARLNQLERDIADGWEEARGFLR"
     gene            complement(12294..13541)
                     /gene="nbmK"
     CDS             complement(12294..13541)
                     /NRPS_PKS="Domain: Aminotran_1_2 (52-181). E-value: 4e-09.
                     Score: 27.9. Matches aSDomain:
                     nrpspksdomains_nbmK_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="nbmK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     346.7; E-value: 2.7e-105)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative NDP-deoxyhexose 4-dehydratase"
                     /product="NbmK"
                     /protein_id="AAM88360.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 5.4e-106,
                     bitscore: 344.6, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.8e-10, bitscore:
                     27.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSVLSDLAFFGGTAAFDQPLLVGRPNRIDRAKLYERLDRALDGQ
                     WLSNGGPLVREFEERVAGLAGVKHAVATCNATAGLQLLAHATGLTGEVIMPSMTFAATP
                     HAMRWIGLTPVFADIDPDTGTLDPDRVAAAVTPRTSAILGVHLWGRLCAADQLRKVADE
                     HGLRLYFDAAHALGCAIDGRPAGSLGDAEVFSFHATKAVNAFEGGAVATDDADLAARIR
                     ALHNFGFDLHGGSPAGGTNAKMSEAAAAMGLTSLDAFPEVIDRNRRNHASYREHLADLP
                     GVLVADHDRHGVNNHQYVIVEIDEATTGIHRDLVMEVLKAEGVHTRAYFSPGCHQLEPY
                     RGQPHAPLTHTEHLAERVLCLPTGTAVDDDDVRRVADLLRLCVTRGRELTSRHRDTAPL
                     AALRTATPTPTIGRSR"
     aSDomain        complement(12999..13385)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nbmK_Aminotran_1_2.1"
                     /evalue="4.00E-09"
                     /label="nbmK_Aminotran_1_2.1"
                     /locus_tag="nbmK"
                     /protein_end="181"
                     /protein_start="52"
                     /score="27.9"
                     /tool="antismash"
                     /translation="LVREFEERVAGLAGVKHAVATCNATAGLQLLAHATGLTGEVIMPS
                     MTFAATPHAMRWIGLTPVFADIDPDTGTLDPDRVAAAVTPRTSAILGVHLWGRLCAADQ
                     LRKVADEHGLRLYFDAAHALGCAID"
     gene            13901..14209
                     /gene="nbmL"
     CDS             13901..14209
                     /codon_start=1
                     /gene="nbmL"
                     /note="cytochrome P450; frameshift generates premature stop
                     codon and truncated protein"
                     /product="truncated NbmL"
                     /protein_id="AAM88361.1"
                     /transl_table=11
                     /translation="MSRTHQGTTASRPVLDLAALGQDFAADPYPTYARLRAEGPAHRVR
                     TPEGDEVWLVVGYDTARAVLADPRFSKDWRNSATPPTEAEAALSHNMLESDPRCGPT"
     gene            14724..17561
                     /gene="nbmM"
     CDS             14724..17561
                     /codon_start=1
                     /gene="nbmM"
                     /gene_functions="regulatory (smcogs) SMCOG1149:LuxR family
                     transcriptional regulator (Score: 912.9; E-value:
                     4.2e-276)"
                     /gene_kind="regulatory"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="hypothetical regulatory protein"
                     /product="NbmM"
                     /protein_id="AAM88362.1"
                     /transl_table=11
                     /translation="MIAIRRRVRRPDEGTSAMNLVERDGETARLRAVLDASAAGEGTLL
                     LVSGPAGSGKTELLRSFRRLAAERGTPVWTVRALPGDRDVPLGVLCQLLRSAQQHGADT
                     STVRDLVDNASRRAGNLTSPADAPLRVDETHQLHDWLRSLSRRTPFLVAVDDLTHADTA
                     SLRFLLYCAAHHDQGGIGFVMTDRASQRAGYRVFRAELLRQPHCRNLWLSGLPPSGVRQ
                     FLTHYYGPEAAERRAPAYHATTGGNPLLLRALTQDRQAARTALGTADGDGPVHGDAFAQ
                     AVLDCLHRSSEGTLETARWLAVLEQSDPLLVERLTGTTAAAVERHIHELAAIGLLDEDG
                     ALGQPAIREAALLDLPAGERTELHRRAAEQLHRDGADEDTVARHLLVGGAPDAPWALPL
                     LERGAQQALFDDRLDDAFRILEFAVRSSTDNTQLARLAPHLVAASWRMNPHMTTRALAL
                     FDRLLSGELQPSHPVMGLIRCLVWYGRLPEAADALSRLRPRTDSEHLEMSLTRMWLAAL
                     CPPLLESLPPSPEPERGPVPVRLAPRTIALQAQAGVFQRGPDNASVAQAEQILQGCRLS
                     EETYEALETALLVLVHADRLDRAQFWSDALLAEAVERRSLGWEAIFAATRAMIAIRCGD
                     LPTARERAELALSHAAPESWGLAVGMPLSALLLACTEAGEYEQAERVLRQPVPDAMFDS
                     RHGMEYMHARGRYWLATGRLHAALGEFMLCGEILGSWNLDQPSIVPWRTSAAEVYLRLG
                     NRQKARALAEAQLALVRPGRSRTRGLTLRVLAAAADGQQAERLHAEAVDMLHDSGDRLE
                     HARALAGMSRHQQAQGDNYRARMTARLAGDMAWACGAYPLAEEIVPGRGGRRAKAVSTE
                     LELPGGPDVDLLSEAERRVAALAARGLTNRQIARRLCVTASTVEQHLTRVYRKLNVTRR
                     ADLPVSLAQDKSVTA"
ORIGIN
        1 gcggtcctcc gggccgccgg ggacgccccg gtcgtcctgc tcgggcactc cggcggcgcc
       61 ctgctcgccc acgagctggc cttccgcctg gagcgggccc atggcaccgc gccggccgga
      121 atcgtgctgg tcgaccccta cccgccgggg catcaggagc ccatcgaggt gtggagccgg
      181 cagctcggcg agggcctgtt cgcgggcgag ctggagccga tgtccgacgc gcggctgctc
      241 gccatgggcc ggtacgcccg cttcctcgcc ggcccgcggc cgggccgcag cagcgcgccc
      301 gtgctcctcg tgcgggcctc cgaacggctg ggcgactggc cggaggagcg cggtgactgg
      361 cgcgcccact gggacctccc gcacagcgtg gcggacgtgc ccggcgacca cttcacgatg
      421 atgcgggacc acgctccggc cgtcgccgtt gccgtcctcg cctggctcga cggcatcgag
      481 cgggacaccg ccgccgggcg gcggaccgcg cagggggcgg accagtgacc gacagagttc
      541 tgaacgtgga cagcagcctg tggatccgac gcttccaccc ctcgccgaac agcgcggtgc
      601 ggctggtctg tctgccgcac gccggtggtt ccgccagcta cttcttccgc ttctcggagg
      661 agctccaccc ctcggtcgag gccttgtcgg tgcagtaccc cggccgccag gaccggcgtg
      721 ccgagccgtg tctggagagc gtcgaggagc tcgccgagca cgtggtcgcg gccaccgaag
      781 cctggtggcg ggagggccgt ctcgccttct tcgggcacag cctcggtgcc tccgtcgcct
      841 acgaggcggc ccgcatcctc gaacagcggc acggggtacg gcccgagggc ctgtacgtct
      901 ccggccggcg cgccccgtcc ctggcaccgg accggctcgt ccaccagctg gacgaccggg
      961 cgttcctggc cgagatccgg cagctcagcg gcacggacga gcggttcctc caggacgacg
     1021 agctgatgcg gctggtgctg cccgcgctgc gcagcgacta caaggcggcg gagacgtacg
     1081 agcaccggcc ctccgcgaag ctcgcctgcc cggtgatggc cctggccggc gaccgcgacc
     1141 cgaaggcgcc gctgaacgag gtggccgagt ggcgccggca caccagcggg ccgttctgcc
     1201 tgcgggcgta ctccggcggt cacttctacc tcaacgacca gtggcacggg atctgcaacg
     1261 acatctccga ccacctgctc gtcacccgcg gcgcgcccga ttcccgcgtc gtgcagcccc
     1321 cgacccgact gatcgaagga gcggcgaaac gatggcagaa cccacggtga ccgacgaccc
     1381 ggcgcgggcg ctcacgcagc ctccgctggg ccgcaccgtc agcgcggtgg ccgaccccga
     1441 gctcggtgcc cacctcctgg agacccgcgg catccactgg atccacgccg cgaacggcga
     1501 cccgtacgcc gccgtgctgc gcgggcaggc cgacgatccg tatcccgcgt acgagcgggt
     1561 gcgcgcccgg ggcgtgctct ccttcagccc gacgggcagc tgggtcaccg ccgatcacgc
     1621 cgtggcggcg agcgtcctgt gctcgacgga gttcggggtg ccgggtgccg acggcgtccc
     1681 ggtgccgcag caggtcctct cctacgggga gggctgcccg ctggagcacg agcaggcgcc
     1741 gcgggcggcc gccgaggtgc cgggggcgtg ggcggggcag cgccgggccg tggtcgagga
     1801 ggtccaccgg cagatcctgg agggtctcgc gccggacccg tcggcttcgt acgccttcga
     1861 gttggtgggg ggtttcgtcc gtccggcggt gacgggcgcg gcggccgcgg tgctcggtgt
     1921 gccggcgggt cggcgcgggg agttcgccga gctggtggag cggctgcggc cgctgtccga
     1981 cagcctgctg gccccgcagt cgctgcggac ggtacgggcg gcggacggcg cgctggccgc
     2041 gttgacggcg ttgctcgccg aagccggtgt ctcggccgcc accgacggct ccgatccctc
     2101 ctccggcccc tccgcgccct cttccgatcc ctccgcttcc tcctccggcc ccaccgcgcc
     2161 ctcctccggc cccaccgcgc cctcgtccgg tgtcgcgggc cggccggacg gggcgctgct
     2221 gtcggcgctc ggtgtcaccg ccgccgtcca gctcaccggg aacgccgtgc tcgccctcct
     2281 cgcgcacccg gagcagtggc gggagctgtg cgcgcggccg gggctcgccg cggccgcggt
     2341 ggaggagaca ctccgctacg acccgccggt gcagctggac gcccgggtgg cccgcgtgga
     2401 aacggagctg gcgggccggc gtctcccggc cggggcgcat gtcgtcgtcc tcaccgccgg
     2461 caccggccgg gacccggggg tcttcacgga cccggagcgt ttcgacctcg cgcgccccga
     2521 cgccacggcg cacctcgcgc tgcaccccgc cggtccgtac ggcccggtgg cgtcgctggt
     2581 gcggctccag gcggaggtcg cgctgcggac cctggccggg cgtttccccg ggctgcggaa
     2641 ggccgggccc gtgctccgtc cccgccgcgc ccctgtcggc cgcgggccgc tgagcgtccc
     2701 ggtcggctcc tgagtccgtt ccgacctccc caccccgcct ccccaccccg acccttcacc
     2761 ggcaaggaag gacacgacgc catgcgcgtc ctgctgacct cgttcgcaca tcacacgcac
     2821 tactacggcc tcgttcccct ggcctgggcg ctgctcgccg ccgggcacga ggtgcgggtc
     2881 gcgagccagc ccgcgctcac ggacaccatc accgggtcag ggctcgcggc cgtgcccgtc
     2941 ggcacggatc acctcatcca cgagtaccgg gtgcggatgg cgggcgagcc gcgcccgaac
     3001 catccggcga tcgccttcga cgaggcccgt agcgagccgc tggactggga ccacgccctc
     3061 ggcatcgacg cgatcctcgc cccgtacttc tatctgctcg ccaacaacga ctcgatgatc
     3121 gacgacctgg tcggcttcgc caggtcctgg cagccggacc tggtgctgtg ggagccgacg
     3181 acgtacgcgg gcgccgtcgc cgcccaggtc acgggcgccg cgcacgcccg ggtcctgtgg
     3241 gggcccgacg tgatggggag cgcccgccgc aagttcgtcg cgctgcggga ccggcagccg
     3301 ccggagcacc gtgaggaccc cacggcggag tggctgacgt ggacgctgga ccggttcggc
     3361 gcctccttcg aagaggagct gctcaccggc cagttcacgg tcgacccgac tccgccgagt
     3421 ctgcgtctcg acacgggtct gccgaccgtc ggggtgcagt acgttccgta caacggcacg
     3481 tcggtcgtgc cggactggct cgccgagccg ccggcgcggc cccgggtctg cctcactctc
     3541 ggtgtctccg cgcgggaggt cctcggcggc gacggggtct cgcaggccga catcctggag
     3601 gcgctcgccg acctcgacat cgagctcgtg gccacgctcg acgcgggtca gcgcgcggag
     3661 atccgctcct atccgaagca cacgcggttc acggacttcg tgccgatgca cgcgctgctg
     3721 ccgagctgtt cggcgatcgt ccaccacggc ggggccggta cgtacgcgac cgccgtgatc
     3781 aacgcggtgc cgcaggtcat gctcgccgag ctgtgggacg cgccggtcaa ggcgcgggcc
     3841 gtcgcggagc agggggcggg gttcttcctg ccgcctgccg gcctcacccc gcaggcggtg
     3901 cgggacgcgg tcgtccgcat cctcgacgac ccctcggtcc tcgccgccgc gcaccggctg
     3961 cgcgaggaga cccatcgcga ccccaccccg gcggggatcg tccccgagct ggagcggctc
     4021 gccgcacagc accgccgccc gccggccgat gcccgccgct gagccgccct cctcgtccga
     4081 gggccccgag cctcaccact gatctccgcc gggggacgct ccccggccac ccaccgaaag
     4141 caggagtccc gtgtacgaag tcgaccacgc cgacgtctac gacctcttct acctcggtcg
     4201 cggcaaggac tacgccgccg aggcctccga catcgccgac ctggtgcgga cccgtacccc
     4261 cgaggcctcc tcgctcctgg acgtggcctg cggtacgggc acgcatctgg agcacttcac
     4321 caaggagttc ggcgacaccg ccggcctgga gctgtccgag gacatgctga cccacgcccg
     4381 gaagcggctg cccgacgcga cgctccacca gggcgacatg cgggacttcc gcctcggccg
     4441 ccggttctcc gcggtggtca gcatgttcag ctccgtcggc tacctgcgga cgacggccga
     4501 actcgacgcg gccgtcgcct cgttcgccgc gcacctggag cccggcggcg tcgtcgtcgt
     4561 cgagccgtgg tggttcccgg agaccttcgc cgacggctgg gtgagcgccg atgtcgtccg
     4621 gcgggacggg cggaccgtgg cccgtgtctc gcactcggtg cgggacggcg acgcgacgcg
     4681 catggaggtg cacttcaccg tggcggaccc gggccgcggc gtacggcact tctccgacgt
     4741 ccacctcatc accctgttcc accgggcgga gtacgaggcg gccttcacgg ccgccgggct
     4801 gcgcgtcgag tacctggagg gcggcccgtc gggccgtggc ctcttcgtcg gggtccccgc
     4861 ctagtccctc gcccggtcac cccacacaga cccccggggc gtcccgggtg caccaagcac
     4921 agagagagaa atccaccgtg acaggtaaga cccgaatacc gcgtgtccgc cgcagccgta
     4981 cgacccccag ggccttcacc ctggccgtcg tcggcaccct gctggcgggc accaccgtgg
     5041 cggccgccgc tcccggcgcc gccggcacgg gccacgtgca gtacacgagc aaggcggcgg
     5101 agctcgtcgc gcagatgacg ctcgacgaga agatcagctt cgtccactgg gcgctggacc
     5161 ccgaccggca gaacgtcggc taccttccgg gcgtgccgcg tctcggcatc ccggagctgc
     5221 gcgccgccga cggcccgaac ggcatccgtc tggtgggcag gaccgccacc gcgctgcccg
     5281 cgccggtcgc cctggccagc accttcgacg actccatggc cgacagctac ggcagggtca
     5341 tgggccgcga cggacgcgcg ctgggccagg acatggttct gggcccgatg atgaacaaca
     5401 tccgggtgcc acacggcggc cggaactacg agaccttcag cgaggacccc ctggtctcct
     5461 cgcgcaccgc ggtcgcccag atcaagggca tccagggtgc gggtctgatg accacggcca
     5521 agcacttcgc ggccaacaac caggagaaca accgcttcag cgtcaacgcc acggtcgacg
     5581 agcagacgct ccgcgagatc gagttcccgg cgttcgaggc gtcctcgaag gccggcgcgg
     5641 cctccttcat gtgtgcctat aacggcgtca acggcaagcc gtcctgcggc aacgacgagc
     5701 tgctcaacaa cgtgctgcgc acgcagtggg gcttccaggg ctgggtgatg tccgactggc
     5761 tcgccacccc gggcacggac gccatcacca agggcctcga ccaggagatg ggcgtcgagc
     5821 tccccggcga catcccgccg ggcgagccct cgccgccggc caagttcttc ggtgacgcgc
     5881 tgaagcaggc cgtcctgaac ggcacggtcc ccgaggcggc cgtgacgcgg tcggcggagc
     5941 gcatcgtcaa ccagatggac aagttcggtc tgctcctcgc gactccggcg ccccgccccg
     6001 agcgtgacaa ggcgggcgcc caggcggtgt cccgcaaggt cgccgagaac ggcgcggtgc
     6061 tcctgcgcaa cgagggccag gccctgccgc tcgccggtga cgccggcaag agcatcgccg
     6121 tcatcggccc gacggccgtc gaccccaagg tcaccggcct gggcagcgcc cacgtcgtcc
     6181 cggactcggc ggcggcgccg ctcgacacca tcaaggcccg cgcgggcgcg ggtgcgacgg
     6241 tgacgtacga gacgggtgag gagaccttcg ggacgcggat cccggcggcg cagctcagcc
     6301 cggcgttcaa ccagggccac cagctggagc cgggcaaggc gggggcgctg tacgacggca
     6361 cgctgaccgt gcccgccgac ggcgagtacc gcatctcggt caaggccacc ggtggctacg
     6421 cgacggtgca gctcggcagc cacaccatcg aggccggtca ggtctacggc aaggtgagca
     6481 gcccgctcct caagctgacc aagggcacgc acaagctcac gatctcgggc ttcgcgatga
     6541 gcgccacgcc gctctccctg gagctgggct gggtgacgcc ggaggcagcc gacgcgacga
     6601 tcgcgaaggc cgtggagtcg gcgcggaagg cccgtacggc catcgtgttc gcgtacgacg
     6661 acggcaccga gggcgtcgac cgtccgaacc tgtcgctgcc gggtacgcag gacaagctga
     6721 tctcggcggt cgccgacgcg aacccgaaca cgatcgtggt cctcaacacc ggttcgtcgg
     6781 tgctgatgcc gtggctgtcc aagacccgcg cggtcctgga catgtggtac ccgggccagg
     6841 cgggcgccga ggcgaccgcc gcgctgctct acggtgacgt gaacccgagc ggcaagctca
     6901 cgcagagctt cccggccgcc gagaaccagc acgccgtcgc cggcgacccg aaccgctacc
     6961 cgggcgtcga caaccagcag acgtacagcg agggcatcca cgtcgggtac cgctggttcg
     7021 acaaggagaa cgtcaagccg ctgttcccgt tcgggcacgg cctgtcgtac acctcgttca
     7081 cgcagagcgc cccgaccgtg gtgcgcacgt ccacgggcgg cctgaaggtc acggtcacgg
     7141 tgcgcaacag cgggcagcgc gcgggccagg aggtcgtcca ggcgtatctc ggcgcgagcc
     7201 cgaaggtgac ggctccgcag gcggagaaga agctcgtggg ctacacgaag gtcgcgctcg
     7261 cggcgggcga gtcgaagacg gtgacggtga acgtcgaccg ccgtcagctg cagtactggg
     7321 acgccgcgtc ggactcgtgg aggacgggaa cgggcagcag gctcctccag accggttcgt
     7381 cctccgcgga cctgaagaac agcagccagg tgaccgtctg gtgacgtgac agggtgcgaa
     7441 gcggcggtgc ccgccacccg ggagggtggc gggcaccgcc tttttcggcc tgctcggccg
     7501 gtcggccacc tgactagggc cggccggcct gctcggccca ttcgcgcacg gcgtcgatca
     7561 cccggagcgc ctgcgtgcgc tccaggtgcg ggccgatcgg caggctgagg acctgccggg
     7621 cgaaactctc ggcccgcggg agcgagcctt ccgggggtgc ttggcccgcg taggcgggcg
     7681 agaggtgcac cggcaccggg tagtgggtga gggtgtcgac gccgcgggag tcgaggtggt
     7741 cgcggagctc gtcgcggcgg tcggtgcgca cggtgaagag gtgccagacg gggtcggtgc
     7801 cgggcgcggt gaccggcagg gcgatgccgg ggaggccggc gagtccggag aggtattcgg
     7861 cggccagcgt cgacctgcgg ccgttccagc tgtcgaggtg ggcgagccgg atccgcagga
     7921 cggcggcctg tatctcgtcc aggcgggagt tggtgccctt cgtctcgtgg ctgtacttct
     7981 gccgggagcc gtagttgcgg agcatccgga gccgttcggc gagcgcgggg tcgccggtga
     8041 cgacggcgcc gccgtcgccg aagcagccga ggttcttgcc cgggtagaag ctgaacgcgg
     8101 ccaccgacgc accggcgccg atccgccggc cccggtagcg ggcgccgtgg gcctgggcgg
     8161 cgtcctcgac gatgtgcagg ccgtgccggt cggcgaggtc gcggagggcg tccaggtcgg
     8221 cggggtgccc gtagaggtgg acggggagca gcgcccgggt gcggggggtg atcgccttct
     8281 cgacgagcag cgggtcgagg gtggggtggt cctcgttcgg ctcgacgggc acgggggtcg
     8341 cgccggtggc ggagaccgcg agccagctgg cgatgtacgt gtgcgagggg acgatcacct
     8401 cgtccccggg tccgatgccg aggccgcgga gcgcgagctg gagggcgtcc atgccgctgt
     8461 tcacgccgac ggcgtggtcg gtctcgcagt aggtggcgaa ctcggcttcg aaggcttcga
     8521 gttcggggcc gaggaggtag cgccccgagt cgagtacgcg ggcgatggcg gcgtcggtct
     8581 ccgggcgcag ttcctcgtag gcggccttga ggtcgaggaa ggggacccgg ccggtctcgg
     8641 tgcgggcggt cacgcggaca cccccacggc ggtggcgggc ggctgcgggg cggtggcggg
     8701 cggctgcggg gcggtggcct tgagcggttc ccaccagtcg cggttctccc ggtaccagcg
     8761 gatggtgcgc gcgaggccgt ccgcgaaggc gatctgcggg cggtagccga gttcgcgctc
     8821 gatcttgccg ccgtcgaggg agtagcgcag gtcgtggccc tggcggtcgg cgacccgccg
     8881 gaccgaggac cagtcggcgc cgagcgagtc caggaggatg ccggtgagtt cgcggttggt
     8941 cagctcccgg ccgccgccga tgtggtagac ctcgccggcc cggccgcccg cgaggacgag
     9001 cgcgatgccc cggcagtggt cgtcggtgtg gacccactcg cggacgttcg cgccgtcgcc
     9061 gtacagcggg agcgtcccgc cgtcgaggag gttcgtcacg aagaggggga tgagcttctc
     9121 ggggtgctgg tacggcccgt agttgttgca gcagcgggtg atccgtacgt cgaggccgta
     9181 ggtgcggtgg taggcgcggg cgacgaggtc ggagccggcc ttggaggccg cgtaggggga
     9241 gttgggttcc agcgggctgc tctcgttcca cgagccggag tcgatcgacc cgtacacctc
     9301 gtcggtggag acgtgcacga cccggccgac gccggcgtcg agggcgcact ggagcagggt
     9361 ctgcgtgccc tggacgttgg tcccggtgaa cacggacgcc cccgcgatgg agcggtcgac
     9421 gtggctctcg gcggcgaagt ggacgacggc gtcgacgccg cgcagttccc gggcgaggag
     9481 gtcggcgtcg cggatgtcgc cgtggacgaa ccgcagccgc gggtccgctt ccaccggggc
     9541 gaggttggcg cggttgcccg cgtaggtgag gctgtccagg acgatcacct caccggcggg
     9601 gacgtcgggg tacgccccgg cgaggagctg ccgcacgaag tgcgagccga tgaagcccgc
     9661 acctccggtc accagaagcc gcactgccgt cttcctttcg gtcgcgctgt cggtggcact
     9721 gccggtggtg gggggaacgc gacggccgcg aggtgccctc acggggctcc ctcgcggccg
     9781 gcgatctcca tcagatagct gccgtactcg gtgcgggaga ggccttctcc caggctgtga
     9841 caggcctcgg cgtcgatgaa gcccatgcgg aaggcgatct cctccaggcc cgcgatccag
     9901 accccctgcc gctcctccag gacctggacg tactgggcgg cccggaggag cgagtcgtgg
     9961 gtgccggtgt cgagccaggc gaagccacgc cccaggtcga cgagttcggc ccggccccgc
    10021 tccaggtaga cgcggttgac gtcggtgatc tccagctcgc cgcgcggcga gggccggatg
    10081 ttcttggcga tgtcgacgac gtcgttgtcg tagaggtaga ggccggtgac ggcgaggtgg
    10141 gagcgcggct tctcgggttt ctcgacgagg ccggtcagcc ggcccgtggc gtcgacctcg
    10201 gcgacgccgt accgctcggg gtccttgacg gggtagccga agagcacgca gccgtcgagg
    10261 cgcgcgatgc tgtcccgaag gagcgagtag aggccgggcc cgtggaagat gttgtcgccc
    10321 aggatcaggg cgcaggtgtc gtcgccgatg tgtccggcgc cgacgaggag cgcgtccgcg
    10381 attcccgcgg gctctttctg gaccgcatag tcgagttcga ttcccaggtg cctgccgttt
    10441 ccgagcagcg actggaagag ttcgatgtgc tgaggcgtgg agattatttg tatctcgcga
    10501 ataccgccga gcatgagaac cgacagcgga tagtagatca tcggtttgtt gtagaccgga
    10561 agaatctgtt tcgaaatgac cgaggtcgcc ggatgcagcc gagttccgct cccgccggcc
    10621 aggactattc ccttcattcc cggaaactag caggaggctg tcggcgatta cggttggcgg
    10681 ggcggagtta ggggggcttt aggggctgcc cagggggagt cccttggccc ctttgggggg
    10741 ggtgggaaaa acgcggaggg cccggccgga cggccgggcc ctcggatggc gtgcggatgc
    10801 ggatgcgggt ctgggcgcgg gtccggctcc gggtgtgggt cagcgcagga agccgcgggc
    10861 ctcctcccag ccgtcggcga tgtcccgctc cagctggttg aggcgggcgg tgacgacctg
    10921 gtcgaagccg tccatgaagt actcgtcgcc gtcgcgggcc gccacccggc cgccgcgttc
    10981 gacgtagtcg cggacgacct cggtgagcga ggtgccgggg cccacgcggc ccgcgatgta
    11041 ccgggtcgcg ccgtccaggt cggggaagcc ggcctcgcgg tacaggtaca cgtcgccgag
    11101 gaggtcgacc tgcaccgcga cctgcgggtg cgcggtgggc cgcatggtgg cgggcttgat
    11161 ccgcagcagt tcggcgtcgg ccccggcctt caggctgttc agggcgtagc cgtagtcgat
    11221 gtggagcccg ggggtgcgct cgcggacccg ctcctcgaag gcggcgaggg cctcctggag
    11281 ctcggcgcgc tcctcctggg gcagcttgcc gtcctcgcgg ccgctgtagt cctcgcggat
    11341 gttgacgaag tcgatcgtcc tgccctgtcc tgactcgtcg aggtcggcga tgaagtcgac
    11401 caggtcgagc aggcggtggg cgcggcccgg gagcacgatg taggcgaagc cgaggttgat
    11461 cggcgcctcg cgttcggcgc ggagctgctg gaagcggcgc aggttctcgc ggacgcggcg
    11521 gaaggcggcc ttcttgccgg tggtctgctc gtactcctcg tcgttgaggc cgtagagcga
    11581 ggtgcggacg gcgtgcaggc cccacagtcc gggctggcgc tccagggtcc gctcggtgag
    11641 ggcgaaggag ttcgtgtaga cggtgggccg caggccgtgc tcggcggcgt gggcggccag
    11701 ggtgccgagg ccggggttgg tgaggggctc caggccgccg gagaagtaca gggcgtgggg
    11761 gttgcccgcg ggtatctcgt cgatgaccga gcggaacatc gcgttgccgg tgtcgagggc
    11821 ggacgggtcg tagcgggcgc cggtgacgcg gacgcagaag tggcagcgga acatgcaggt
    11881 cgggccgggg tagaggccga cgctgtacgg gaagacgggc ttgccggcga gggccgagtc
    11941 gaagactccg cgccgttcga gcgggagcag ggtgttctgc cagtacgccc ccgcggggcc
    12001 gccctccacg gccgcccgga gctccgggac ccgcgggaac agggcgagga ggcgccggaa
    12061 ggcgtcccgg tcgacgccca ggtcgtgacg ggcctcttcg agcggggtga aggggctgtt
    12121 gccgtagcgc acggcgagcc cgacgaggtg gcgggcggtg cttccggcct cgtcggacgg
    12181 cacgagaccg ccggcggcga ggctctggcc gacggcgcgg accgccgccc ccagatcggc
    12241 tccggggtgt gcgcagcgtg cggacggggc ggtggcgacg ggggcggggg cggtcatcgg
    12301 gagcgtccaa tcgtgggcgt gggcgtggct gtccggaggg ccgcgagcgg ggccgtgtcg
    12361 cggtggcgcg aggtcagttc gcgcccgcgg gtcacgcaga gtctcagcag gtcggcgacc
    12421 cggcggacgt cgtcgtcgtc gacggcagtg ccggtcggca ggcacagcac gcgctcggcg
    12481 aggtgttcgg tgtgggtcag cggggcgtgc ggctgcccgc ggtacggctc cagttggtgg
    12541 cagcccgggg agaagtaggc gcgggtgtgg acgccttcgg ccttcaggac ctccatcacg
    12601 aggtcgcggt ggatgccggt ggtggcctcg tcgatctcga cgatcacgta ctggtggttg
    12661 ttgacgccgt ggcggtcgtg gtcggcgacg aggacgccgg ggaggtccgc caggtgctcg
    12721 cggtaggagg cgtggttgcg ccggttccgg tcgattacct cggggaacgc gtcgagggag
    12781 gtgaggccca tggcggcggc ggcctcgctc atcttggcgt tggtgccgcc ggcggggctg
    12841 ccgccgtgca ggtcgaagcc gaagttgtgg agggcccgga tccgggcggc gaggtcggcg
    12901 tcgtcggtgg cgacggcgcc gccctcgaag gcgttgacgg ccttggtggc gtggaagctg
    12961 aagacctcgg cgtcgccgag gctgccggcg ggccggccgt cgatcgcgca gccgagggcg
    13021 tgtgcggcgt cgaagtacag ccgcaggccg tgttcgtcgg cgaccttccg cagctggtcg
    13081 gcggcgcaga ggcggcccca gaggtggacg ccgaggatgg ccgaggtgcg gggcgtgacg
    13141 gcggcggcca cccggtccgg gtcgagggtg ccggtgtccg ggtcgatgtc ggcgaagacc
    13201 ggggtgaggc cgatccagcg catcgcgtgc ggggtggcgg cgaaggtcat cgacggcatg
    13261 atcacctcac cggtcaggcc ggtggcgtgc gccaggagct ggagcccggc cgtggcgttg
    13321 caggtggcca cggcgtgctt gacgccggcg aggccggcga cgcgctcctc gaactcgcgg
    13381 acgagcgggc cgccgttgga cagccactgg ccgtcgagcg cgcggtcgag ccgctcgtag
    13441 agcttggcgc ggtcgatgcg gttgggccgc cccacgagga gcggctgatc gaaagcggcg
    13501 gtgccgccga agaatgcgag gtcggataag acgcttttca cggatgttcc ctccgggcca
    13561 ccgtcacgaa atgattcgcc gatccgggaa tcccgaacga ggtcgccgcg ctccaccgtg
    13621 acgtacgacg agatggtcga ttgtggtggt cgatttcggg gggactctaa tccgcgcgga
    13681 acggaccgac aagagcgcac tgtggacttc gaatgtgctt cggatcacat ccacctccgg
    13741 ggtattccat cggcggcccg aatgtgatga tgcttgtcaa gatccgggaa tcagcggagc
    13801 cgccgggagg gccggggcct gctccgcgga agagtacgcg cgagaagtcc cgttcctctt
    13861 cccgtttccg ttccacttcc ggcccggtct ggagttcttc gtgagccgca cccaccaggg
    13921 aacgaccgct tctcgccccg tgctcgacct ggcagccctg gggcaggact tcgcggccga
    13981 tccgtacccg acgtacgcga gactgcgtgc cgagggtccg gcccaccggg tgcgcacccc
    14041 cgaaggggac gaggtgtggc tggtcgtcgg ctacgacacg gcgcgggcgg tcctcgccga
    14101 tccccggttc agcaaggact ggcgcaactc cgcgactccc ccgaccgagg ccgaggccgc
    14161 gctcagccac aacatgctgg agtccgaccc gcgctgcggg ccgacctgac gctcttggac
    14221 ggcgcggtgg aggagatgct gcgctacgga ggacccgtgg agtccgcgac gtaccgcttc
    14281 ccggtcgagc ccgtcgacct ggacggcacg gtcctcccgg ccggcgagac ggtcctcgtc
    14341 gtgctggccg acgcccaccg cacaccggag cgcttccccg acccgcaccg cttcgacatc
    14401 cgccgcgaca ccgccggcca cctcgccttc gggcacggca tccacttctg caccggcgcc
    14461 ccactggccc ggatggaggc ccggatcgcc gtccgcgccc tcctcgaacg ctgcccggac
    14521 ctcgccctgg acgtctcccc cggcgaactg ttctggtacc cgaacccgat gatccgcgga
    14581 ctcgagtccc tgccgatccg ttggcggagc ggccgggagg cgggccggcg cgtaccggtc
    14641 gaaccggcct gtcgcccctg actgccccgc cgcgcgacac cccccggatc agcccctctc
    14701 cgccgtaaca agacctggtt agagtgattg ccatacggcg aagggttcgg cgcccggacg
    14761 aggggacttc cgcgatgaat ctggtggaac gcgacgggga aacagcccgc ctcagggccg
    14821 ttcttgacgc atccgccgca ggtgagggga cgctgttact cgtctccgga ccggccggca
    14881 gcggcaagac cgagctgctg cggtcgttcc ggcgtctggc ggccgagcgg gggacacccg
    14941 tctggacggt ccgcgcgtta ccgggcgacc gggacgtccc gctgggtgtg ctctgccagt
    15001 tactgcgcag cgcccagcag cacggtgccg acacgtccac cgtccgcgac ctggtcgaca
    15061 acgcctcccg gcgcgccggg aacctcacct cccccgcgga cgccccgctc cgcgtcgacg
    15121 agacacacca gctgcacgac tggctgcgct ccctctcgcg ccgcaccccg ttcctcgtcg
    15181 ccgtcgacga cctgacccac gccgacaccg cgtccctgag attcctcctg tactgcgccg
    15241 cccaccacga ccagggcggc atcggcttcg tcatgaccga ccgggcctcg cagcgcgccg
    15301 ggtaccgcgt cttccgcgcc gagctgctcc gccagccgca ctgccgcaat ctgtggctct
    15361 ccggacttcc tcccagcggg gtacggcagt tcctcacgca ctactacggc cccgaggcgg
    15421 ccgagcggcg agctcccgcg taccacgcga cgaccggggg gaacccgctg ctcctccggg
    15481 cgctgaccca ggaccggcag gcggcccgca cggccctcgg cacggccgac ggcgacggtc
    15541 ccgtgcacgg ggacgccttc gcccaggccg tcctcgactg cctgcaccgc agctccgagg
    15601 gcacactgga gaccgcccgc tggctagccg tcctcgaaca gtccgacccg ctcctcgtgg
    15661 agcggctcac ggggacgacc gccgccgccg tcgagcgcca catccacgaa ctcgccgcca
    15721 tcggcctcct ggacgaggac ggcgccctcg ggcagcccgc gatccgcgag gccgccctcc
    15781 tggacctgcc ggccggggaa cgcaccgagc tgcaccggcg cgccgcggaa cagctgcacc
    15841 gggacggcgc cgacgaggac accgtggccc gtcatctgct ggtcggcggc gcccccgacg
    15901 cgccgtgggc gctccccctg ctcgaacggg gcgcacagca ggccctcttc gacgaccgtc
    15961 tcgacgacgc cttccggatc ctcgagttcg ccgtgcggtc cagcaccgac aacacccagc
    16021 tggcccgcct cgccccgcac ctcgtcgcgg cctcctggcg gatgaacccg cacatgacga
    16081 cccgggccct cgccctcttc gaccggctcc tgagcggtga actgcagccc agccacccgg
    16141 tcatgggtct gatccgctgc ctcgtctggt acgggcggct gcccgaggcc gccgacgcgc
    16201 tgtcccggct gcggccccgc accgacagcg agcacctgga gatgtcgctg acccgcatgt
    16261 ggctggcagc gctgtgccct ccgcttctgg agtccctgcc gccgtcgccc gaaccggagc
    16321 gcggtcccgt cccggtgcgg ctcgcgcccc gcacgatcgc gctccaggcc caggccggcg
    16381 tcttccagcg gggcccggac aacgcgtcgg tcgcacaggc cgagcagata ctgcagggct
    16441 gccggctctc ggaggagacg tacgaggccc tggagacagc cctgctcgtc ctcgtccacg
    16501 cggaccggct cgaccgggcg cagttctggt ccgacgcgct gctcgcggag gcggtggagc
    16561 ggcggtcgct cggctgggag gcgatcttcg ccgcgacccg ggcgatgatc gcgatccgct
    16621 gcggggacct cccgacggcc cgggagcggg ccgagcttgc gctctcccac gcggcgccgg
    16681 agagctgggg gctcgccgtg ggcatgccgc tctccgcgct gctgctcgcc tgcacggagg
    16741 ccggcgagta cgagcaggcg gagcgggtcc tgcggcagcc ggtgccggac gcgatgttcg
    16801 actcgcggca cggcatggag tacatgcacg cgcggggccg ctactggctg gcgacgggac
    16861 gactgcacgc ggcactgggc gagttcatgc tctgcgggga gatcctgggc agctggaacc
    16921 tcgaccagcc gtcgatcgtg ccctggcgga cctcggccgc cgaggtgtac ctgcggctcg
    16981 gcaaccgcca gaaggcgcgg gcgctggccg aggcgcagct cgccctggtc cggccggggc
    17041 gctcccgcac ccggggcctc accctgcggg tccttgcggc cgcggcggac ggccagcagg
    17101 cggagcgcct gcacgccgag gcggtggaca tgctccacga cagcggcgac cggctcgaac
    17161 acgctcgcgc gctggccggg atgagccgcc accagcaggc acagggagac aactaccggg
    17221 cccggatgac ggcgcggctg gccggtgaca tggcgtgggc ctgcggcgcg tacccgctgg
    17281 ccgaggagat cgtgccgggc cgcggcggcc gccgcgcgaa ggcggtgagc acggaactgg
    17341 agctcccggg cggccccgac gtcgacctcc tctcggaggc cgaacgccgc gtcgcggccc
    17401 tggccgcccg gggcctgacg aaccgccaga tagcgcgccg tctctgtgtc accgcgagca
    17461 cggtcgaaca gcacctgacg cgcgtctacc gcaaactgaa cgtcacccgc cgagcagacc
    17521 tcccggtaag cctggcccag gacaagtccg tcacggcata ggccggcggg ggccgtgggc
    17581 acgccggggg gacagtgccc ggtacgacgc cggcaccccc ggtcaggcct gtacccggca
    17641 ggcgcctcgg tcggcgtatc gggac
//
