LOCUS       BGC0000902              3903 bp    DNA     linear   BCT 27-FEB-2015
DEFINITION  Saccharopolyspora erythraea NRRL2338 complete genome.
ACCESSION   BGC0000902
VERSION     BGC0000902
KEYWORDS    .
SOURCE      Saccharopolyspora erythraea NRRL 2338
  ORGANISM  Saccharopolyspora erythraea NRRL 2338
            Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
            Saccharopolyspora.
COMMENT     Project: 18489.
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 21:00:37
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3903
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3903
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[1777:2881]"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1778..2881
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     cand_cluster    1..3903
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..3903
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000902"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..3903
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..540)
                     /locus_tag="SACE_1241"
     CDS             complement(1..540)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SACE_1241"
                     /db_xref="EnsemblGenomes-Tr:CAM00566"
                     /db_xref="GOA:A4F941"
                     /db_xref="InterPro:IPR006045"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:A4F941"
                     /locus_tag="SACE_1241"
                     /product="hypothetical protein"
                     /protein_id="CAM00566.1"
                     /transl_table=11
                     /translation="MTGLMLPPGSGRRLVAGAQDVTFKVTGEHSRAASSFEVVVPPGFD
                     VGAHVHTRSEELFYVLDGELDLLAFEPVTRSGDNWREWESDTGQRVLRAGPGSVMFVPP
                     GCPHAFANSSGAPAKMFFQSSPPTHHERYFEELIEILQAPGGVDHGAVEDLRRRYDIEQ
                     LTPLKYAPPVASQPTS"
     gene            complement(576..1781)
                     /gene="cyp25"
                     /locus_tag="SACE_1242"
     CDS             complement(576..1781)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SACE_1242"
                     /db_xref="EnsemblGenomes-Tr:CAM00567"
                     /db_xref="GOA:A4F942"
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002397"
                     /db_xref="InterPro:IPR017972"
                     /db_xref="UniProtKB/TrEMBL:A4F942"
                     /function="Cytochrome P450"
                     /gene="cyp25"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 384; E-value: 1.3e-116)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SACE_1242"
                     /product="cytochrome P450"
                     /protein_id="CAM00567.1"
                     /sec_met_domain="p450 (E-value: 7.7e-27, bitscore: 82.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDRCPARMYDPADLPGMTFDPVFLELLRDEPVARIRMRYGEGEA
                     WLLTRYEDVKFVTSDPRFSRKIMGRPFPKMTKHHIPMDRAISFSDPPEHARVRRVVARD
                     FSPGSIERLRPTAEKIMHRYLDELVASGPPADLVRHVTSPFPMAVLGELMGIPESDRQW
                     LIDCSSQVLSMAPDQAAVDRINGIKAEVAEYFLALVESRRADPRDDVVSTVAAARERGD
                     LDDEEVGAMTVLLALNGWHAVRNNSTNMVYVLLTDPELRSRLKADLALVPTAVEELLRY
                     IPHKRGIGQPRIATEDVDIRGVRISKGDVVYVSYIAANWDEEVYPEPDRVDLDRPEVPH
                     LAFGHGPHYCMGPMLARMESQVLLSSLLTRLPDLALAVPPEQVAWQPNALIRGPVELPV
                     TW"
     gene            complement(1778..2881)
                     /gene="rppA"
                     /locus_tag="SACE_1243"
     CDS             complement(1778..2881)
                     /EC_number="2.3.1.74"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SACE_1243"
                     /db_xref="EnsemblGenomes-Tr:CAM00568"
                     /db_xref="GOA:A4F943"
                     /db_xref="InterPro:IPR011141"
                     /db_xref="InterPro:IPR012328"
                     /db_xref="InterPro:IPR013601"
                     /db_xref="InterPro:IPR016038"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="UniProtKB/TrEMBL:A4F943"
                     /function="predicted naringenin-chalcone synthase"
                     /gene="rppA"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_C"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:chalcone and stilbene synthase domain protein
                     (Score: 387.2; E-value: 9.5e-118)"
                     /gene_kind="biosynthetic"
                     /locus_tag="SACE_1243"
                     /product="putative type III polyketide synthase"
                     /protein_id="CAM00568.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 3.1e-19,
                     bitscore: 57.4, seeds: 21, tool: rule-based-clusters)"
                     /sec_met_domain="Chal_sti_synt_C (E-value: 1.5e-22,
                     bitscore: 68.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVLCTPAVAVPEHVITVEETLDLARRVHADHPQLPLVLRLISNT
                     GVRERHLIRPIEDTLEHPGFEVRNRIYEEQAKQRVPAVVREALDSAELGPEDIDLIVYV
                     SCTGFMMPSLTAWLINSMGFRMSTRQLPIAQLGCAAGGAAINRAHDFCTAYPDANALIV
                     SCEFCSLCYQPTDDDIGSLLSNGLFGDAVAAAVVRGHGGTGVRLERNASSMIPETEDWI
                     SYAVKATGFHFQLDKRVPKTMEPLAPALRALAEDHRWDVAGLDFYVIHAGGPRILDDLT
                     KFLGVPSEAFRHSRATLAQYGNIASAVVLDALRRIIEEGRLESGARGMIAGFGPGITAE
                     MSVGTWVPHDVLLHGEHSTTSAPGGNR"
     gene            complement(3235..3903)
                     /locus_tag="SACE_1244"
     CDS             complement(3235..3903)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SACE_1244"
                     /db_xref="EnsemblGenomes-Tr:CAM00569"
                     /db_xref="InterPro:IPR002577"
                     /db_xref="InterPro:IPR003033"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="UniProtKB/TrEMBL:A4F944"
                     /function="predicted transcriptional regulators"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1167:transcriptional regulator (Score: 101.5; E-value:
                     2.4e-31)"
                     /gene_kind="regulatory"
                     /locus_tag="SACE_1244"
                     /product="transcriptional regulator"
                     /protein_id="CAM00569.1"
                     /transl_table=11
                     /translation="MGSRTYGQFCGLARALEIVGERWALLIVRDLAVGPKRFTDLRQGL
                     PKIPTNVLSTRLKELEQSDVVRRRVLPRPAAAVVYELTEYGRGLEDIVIRLGRWGARTL
                     GEPRQDEIVTPDSMIMALRATFRPEAARGHRAGYELRLGEVVVHARVDDGELETGEGEL
                     SGADLVIETGPAVRALLAGELTSDEAIANGSVHLTGDSGLLATFAEMFQIPRSVAPLSA
                     "
ORIGIN
        1 tcacgaggtg ggctgcgaag cgacgggcgg cgcgtacttc agcggcgtga gctgctcgat
       61 gtcgtagcgc cgacgcaggt cttccaccgc gccgtggtcc acaccgcccg gtgcttgcag
      121 gatctcgatc agctcctcga agtaccgctc gtggtgcgtc ggcggcgagg actggaagaa
      181 catcttcgcc ggtgcgccgc tggagttggc gaaggcgtgc gggcagccgg gcgggacgaa
      241 catgacgctg cccggcccgg cgcgcagcac ccgctgtccc gtgtcgctct cccactcccg
      301 ccagttgtcg ccgctgcgcg tcaccggctc gaacgccagc aggtcgagct cgccgtcgag
      361 cacgtagaac agctcctcgc tgcgggtgtg cacgtgcgcg ccgacgtcga acccgggcgg
      421 gacgacgacc tcgaagctcg acgccgcccg cgagtgctcg ccggtgacct tgaacgtgac
      481 gtcctgcgcc ccggcgacga gccgcctgcc gctgcccggt ggcagcatga gtccggtcat
      541 gggttcgggt ccttctgcgc tgggactggc tcgggctacc aggtcacggg gagctcgacc
      601 ggcccccgga tcaacgcgtt gggctgccag gccacctgct ccggcggcac cgccagcgcg
      661 aggtccggca gccgcgtcag cagcgaggac agcagcacct gcgactccat ccgcgccagc
      721 atcggcccca tgcagtagtg cgggccgtgc ccgaacgcca ggtgcggcac ctccgggcgg
      781 tcgaggtcga cccggtcggg ctcggggtag acctcctcgt cccagttggc ggcgatgtag
      841 gagacgtaga cgacgtcgcc cttggagatc cgcacgcccc ggatatcgac gtcctcggtg
      901 gcgatgcgcg gctgtccgat cccgcgcttg tgcgggatgt agcgcagcag ctcctcgacc
      961 gcggtcggga cgagcgcgag gtcggccttc agccgggagc gcagctcggg gtcggtcagc
     1021 agcacgtaga ccatgttcgt gctgttgttg cggaccgcgt gccagccgtt gagcgccagc
     1081 agcacggtca tcgcgccgac ctcctcgtcg tcgaggtcgc cgcgttcgcg ggccgcggcg
     1141 accgtgctga ccacgtcgtc gcgggggtcc gcgcgccggc tttcgaccag tgcgaggaag
     1201 tactcggcga cctcggcctt gatcccgttg atgcggtcca cggcggcctg gtcgggcgcc
     1261 atgctcagca cctgggacga gcaatcgatc agccactgcc ggtcggactc cgggatgccc
     1321 atcagctcgc cgagcaccgc catcgggaac ggcgaggtca cgtggcgtac caggtcggcg
     1381 ggcggcccgg aggccaccag ctcgtccagg tatcggtgca tgatcttctc ggccgtcggg
     1441 cgcagccgct cgatggagcc ggggctgaag tccctggcga ccacccggcg cacccgcgcg
     1501 tgctcgggcg ggtcggagaa gctgatcgcc cggtccatcg ggatgtggtg tttggtcatc
     1561 ttcgggaacg gccggcccat gatcttgcgg ctgaaccgcg ggtccgacgt cacgaacttg
     1621 acgtcctcgt agcgggtcag cagccacgcc tcgccctcgc cgtagcgcat ccggatgcgg
     1681 gcgaccggct cgtcgcgcag aagttccagg aacaccgggt cgaaggtcat cccgggcagg
     1741 tccgccgggt cgtacattcg agcggggcag cggtcggtca tcggttgcct cccggggcgg
     1801 acgtggtcga gtgctcgccg tgcagcagga cgtcgtgcgg gacccaggtg ccgacggaca
     1861 tctccgcggt gatgccgggg ccgaagccgg cgatcatgcc gcgggcaccg gactccagcc
     1921 gcccctcctc gatgatgcgc cgcagcgcgt cgaggacgac cgcgctggcg atgttgccgt
     1981 actgggccag cgtcgcccgg ctgtgccgga acgcctcgga cggcacgccc aggaacttgg
     2041 tcaggtcgtc gaggatgcgc gggccgcccg cgtggatgac gtagaagtcc agccccgcga
     2101 cgtcccagcg gtggtcctcg gccagcgcgc gcagcgccgg cgccagcggc tccatcgtct
     2161 tgggcacccg cttgtcgagc tggaagtgga agccggtggc cttgacggcg taggagatcc
     2221 agtcctcggt ctcggggatc atcgacgacg cgttgcgctc caggcggacc ccggtcccgc
     2281 cgtgcccgcg caccaccgcg gcggcgacgg cgtcgccgaa cagtccgttc gacagcagcg
     2341 aaccgatgtc gtcgtcggtc ggctggtagc acagcgagca gaactcgcag gacacgatga
     2401 gcgcgttggc gtcggggtag gcggtgcaga agtcgtgcgc ccggttgatc gcggcgccgc
     2461 ccgcggcgca gccgagctgc gcgatgggca gctgccgggt gctcatgcgg aagcccatcg
     2521 agttgatcag ccacgcggtc agcgagggca tcatgaagcc ggtgcaggag acgtagacga
     2581 tgaggtctat gtcctcgggc cccagctcgg cgctgtcgag ggcctctcgc accacggcgg
     2641 gcacgcgctg cttggcctgc tcctcgtaga tccggttgcg gacctcgaaa cccgggtgct
     2701 cgagggtgtc ctcgatcggc ctgatcagat ggcgctcgcg cacgccggtg ttgctgatca
     2761 gccgaaggac gagcggtagc tgcgggtggt ccgcgtggac gcggcgggcc aggtcgaggg
     2821 tctcctcgac cgtgatgacg tgctccggga ccgcgaccgc aggggtgcat agaactgcca
     2881 ccgatgcctc cattgtgtac gtgcgcgctg aacacggtct gacgcattgc ggcggaggtc
     2941 ggtggtcatc ccgtggagca gcggttccgg ttgcctggtg taccggtcgt ccttcggtcg
     3001 acgacgggac gcgggacttc ggcctccctc cgcggggaga agtggcgcac cattgacatc
     3061 gaccgaccgg gcgcagtgct ttatcagtca agtgagcttt tcactcggct ggccaactaa
     3121 tagggggaaa ttaacgagat cagaccacag tggagcggcg gcccccgcga ccttgtgata
     3181 cggcggtttc gtcgcccgtt cggtgtgtgg agcggcggct cgtgcgcgcc tgtttcaggc
     3241 ggagagcgga gcgacggagc gcgggatctg gaacatttcg gcgaaggtcg ccagcaggcc
     3301 gctgtcgccg gtgagatgca cgctgccgtt ggcgatcgcc tcgtcggagg tgagctcccc
     3361 ggccagcagg gcgcgcacgg ccgggccggt ctcgatgacc aggtccgcgc cggacagctc
     3421 gccctcgccg gtttcgagtt cgccgtcgtc gacccgggcg tggaccacga cctcgccgag
     3481 gcgcagctcg tagcccgccc ggtgcccgcg cgccgcctcc gggcggaagg tcgcgcgcag
     3541 ggccatgatc atcgagtccg gcgtgacgat ctcgtcctgg cgtggctcgc cgagggtccg
     3601 ggctccccag cggccgagcc ggatcacgat gtcctccagg ccgcggccgt actcggtgag
     3661 ctcgtagacc acggccgccg cggggcgcgg aagcacgcgg cgccgcacca cgtccgactg
     3721 ctccaactcc ttcaaccgcg tcgacaggac gttggtcggg atcttgggca agccctggcg
     3781 caggtcggtg aagcgtttcg gtcccacggc gagatcgcgc acgatgagca gcgcccaccg
     3841 ctcgccgacg atctccagtg cgcgtgccag cccgcagaac tggccgtagg tccggcttcc
     3901 cat
//
