BGC0000907: lincomycin biosynthetic gene cluster from Streptomyces lincolnensis
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 38,217 nt. (total: 38,217 nt).
This entry is originally from NCBI GenBank EU124663.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000907
Short description lincomycin biosynthetic gene cluster from Streptomyces lincolnensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
EU124663.1
via
Compounds
  • lincomycin
Species Streptomyces lincolnensis [taxonomy]
References
Chemical products information
lincomycin Evidence:
Copy SMILES
C18H34N2O6S1
Chemical database entries
PubCHEM
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABX00628.1
1 - 453 (+) Sli1
    copy AA seq
    copy Nt seq
    • ABX00596.1
    2497 - 3951 (+) LmrA
      copy AA seq
      copy Nt seq
      • ABX00597.1
      4320 - 6125 (+) LmbA
        copy AA seq
        copy Nt seq
        • ABX00598.1
        6215 - 6691 (+) LmbB1
          copy AA seq
          copy Nt seq
          • ABX00599.1
          6688 - 7641 (+) LmbB2
            copy AA seq
            copy Nt seq
            • ABX00600.1
            7731 - 9260 (-) LmbC
              copy AA seq
              copy Nt seq
              • ABX00601.1
              9292 - 10359 (+) LmbD
                copy AA seq
                copy Nt seq
                • ABX00602.1
                10377 - 11189 (-) LmbE
                  copy AA seq
                  copy Nt seq
                  • ABX00603.1
                  11237 - 12520 (-) LmbF
                    copy AA seq
                    copy Nt seq
                    • ABX00604.1
                    12517 - 13317 (-) LmbG
                      copy AA seq
                      copy Nt seq
                      • ABX00605.1
                      13366 - 14817 (-) LmbIH
                        copy AA seq
                        copy Nt seq
                        • ABX00606.1
                        14810 - 15559 (-) LmbJ
                          copy AA seq
                          copy Nt seq
                          • ABX00607.1
                          15622 - 16194 (+) LmbK
                            copy AA seq
                            copy Nt seq
                            • ABX00608.1
                            16208 - 17521 (-) LmbL
                              copy AA seq
                              copy Nt seq
                              • ABX00609.1
                              17518 - 18492 (-) LmbM
                                copy AA seq
                                copy Nt seq
                                • ABX00610.1
                                18489 - 19346 (-) LmbN
                                  copy AA seq
                                  copy Nt seq
                                  • ABX00611.1
                                  19343 - 20347 (-) LmbZ
                                    copy AA seq
                                    copy Nt seq
                                    • ABX00612.1
                                    20344 - 21327 (-) LmbP
                                      copy AA seq
                                      copy Nt seq
                                      • ABX00613.1
                                      21324 - 22022 (-) LmbO
                                        copy AA seq
                                        copy Nt seq
                                        • ABX00614.1
                                        22032 - 23180 (-) LmbS
                                          copy AA seq
                                          copy Nt seq
                                          • ABX00615.1
                                          23177 - 23839 (-) LmbR
                                            copy AA seq
                                            copy Nt seq
                                            • ABX00616.1
                                            23901 - 25007 (-) LmbQ
                                              copy AA seq
                                              copy Nt seq
                                              • ABX00617.1
                                              25004 - 26314 (-) LmbT
                                                copy AA seq
                                                copy Nt seq
                                                • ABX00618.1
                                                26311 - 27030 (-) LmbV
                                                  copy AA seq
                                                  copy Nt seq
                                                  • ABX00619.1
                                                  27348 - 28400 (+) LmbW
                                                    copy AA seq
                                                    copy Nt seq
                                                    • ABX00620.1
                                                    28455 - 29294 (-) LmrB
                                                      copy AA seq
                                                      copy Nt seq
                                                      • ABX00621.1
                                                      29389 - 30279 (-) LmbX
                                                        copy AA seq
                                                        copy Nt seq
                                                        • ABX00622.1
                                                        30276 - 31163 (-) LmbY
                                                          copy AA seq
                                                          copy Nt seq
                                                          • ABX00623.1
                                                          31309 - 31986 (-) LmbU
                                                            copy AA seq
                                                            copy Nt seq
                                                            • ABX00624.1
                                                            32696 - 34348 (-) LmrC
                                                              copy AA seq
                                                              copy Nt seq
                                                              • ABX00625.1
                                                              34751 - 35848 (-) Sli2
                                                                copy AA seq
                                                                copy Nt seq
                                                                • ABX00626.1
                                                                36033 - 36566 (-) Sli3
                                                                  copy AA seq
                                                                  copy Nt seq
                                                                  • ABX00627.1
                                                                  36804 - 38075 (+) Sli4
                                                                    copy AA seq
                                                                    copy Nt seq
                                                                    Biosynthesis information
                                                                    Annotation changelog

                                                                    Entry version: 4

                                                                    Date
                                                                    Changes
                                                                    Submitters
                                                                    Reviewers
                                                                    Update chemical activity to schema version 2.11
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                    Entry version: 3

                                                                    Date
                                                                    Changes
                                                                    Submitters
                                                                    Reviewers
                                                                    Updated bioactivity data
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                    Entry version: 2

                                                                    Date
                                                                    Changes
                                                                    Submitters
                                                                    Reviewers
                                                                    Migrated from v1.4
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    Updated compound(s) information (NPAtlas curation)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                    Entry version: 1

                                                                    Date
                                                                    Changes
                                                                    Submitters
                                                                    Reviewers
                                                                    Submitted
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    Similar known gene clusters from MIBiG 4.0
                                                                    Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                                    Click on reference genes to show details of similarities to genes within the current region.
                                                                    Click on an accession to open that entry in the MiBIG database.