BGC0000914: methylenomycin A biosynthetic gene cluster from Streptomyces coelicolor A3(2)
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 231,676 - 251,017 nt. (total: 19,342 nt).
This entry is originally from NCBI GenBank AL589148.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000914
Short description methylenomycin A biosynthetic gene cluster from Streptomyces coelicolor A3(2)
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Other
Loci NCBI GenBank: AL589148.1
Compounds
  • methylenomycin A
Species Streptomyces coelicolor A3(2) [taxonomy]
References
Chemical products information
methylenomycin A
Copy SMILES
C9H10O4
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAC36752.1
  • mmyF
231676 - 232200 (-) putative oxidoreductase, MmyF
copy AA seq
copy Nt seq
  • CAC36753.1
  • mmyY
232231 - 232692 (-) hypothetical protein, MmyY
copy AA seq
copy Nt seq
  • CAC36754.1
  • mmyB
232923 - 233864 (+) putative DNA-binding protein, MmyB
copy AA seq
copy Nt seq
  • CAC36755.1
  • mmyQ
233951 - 234604 (+) hypothetical protein, MmyQ
copy AA seq
copy Nt seq
  • CAC36756.1
  • mmyE
234674 - 235837 (+) putative enoyl reductase, MmyE
copy AA seq
copy Nt seq
  • CAC36757.1
  • mmyD
236410 - 237429 (+) hypothetical protein, MmyD
copy AA seq
copy Nt seq
  • CAC36758.1
  • mmyX
237541 - 238245 (+) putative ATP/GTP-binding protein, MmyX
copy AA seq
copy Nt seq
  • CAC36759.1
  • mmyC
238242 - 239240 (+) putative acyl carrier protein synthase, MmyC
copy AA seq
copy Nt seq
  • CAC36760.1
  • mmyA
239304 - 239552 (+) putative acyl carrier protein, MmyA
copy AA seq
copy Nt seq
  • CAC36761.1
  • mmyP
239676 - 240374 (+) hypothetical protein, MmyP
copy AA seq
copy Nt seq
  • CAC36762.1
  • mmyK
240371 - 240991 (+) putative ATP/GTP-binding protein, MmyK
copy AA seq
copy Nt seq
  • CAC36763.1
  • mmr
241054 - 242481 (-) methylenomycin A resistance protein, Mmr
copy AA seq
copy Nt seq
  • CAC36764.1
  • mmyJ
242698 - 243033 (+) hypothetical protein, MmyJ
copy AA seq
copy Nt seq
  • CAC36765.1
  • mmyG
242996 - 244177 (-) putative oxidoreductase, MmyG
copy AA seq
copy Nt seq
  • CAC36766.1
  • mmyO
244260 - 245381 (-) putative monooxygenase, mmyO
copy AA seq
copy Nt seq
  • CAC36767.1
  • mmyT
245412 - 246221 (-) putative thioesterase, MmyT
copy AA seq
copy Nt seq
  • CAC36768.1
  • mmfR
246362 - 247006 (-) putative 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acid-dependent transcriptional regulator (TetR-family), MmfR
copy AA seq
copy Nt seq
  • CAC36769.1
  • mmfL
247201 - 248262 (+) 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acid biosynthesis protein, MmfL
copy AA seq
copy Nt seq
  • CAC36770.1
  • mmfH
248259 - 249461 (+) putative oxidoreductase involved in 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acid biosynthesis, MmfH
copy AA seq
copy Nt seq
  • CAC36771.1
  • mmfP
249458 - 250255 (+) putative phosphatase involved in 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acid biosynthesis, MmfP
copy AA seq
copy Nt seq
  • CAC36772.1
  • mmyR
250406 - 251017 (+) putative 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acid-dependent transcriptional regulator (TetR-family), MmyR
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.