Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000914.1:
Cluster 1Other119342

BGC0000914, methylenomycin biosynthetic gene cluster from Streptomyces coelicolor. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: methylenomycin
PubChem ID: 122733
SMILES string: Copy to clipboard
Molecular formula: C9H10O4
Average molecular mass: 182.175 Da

Class-specific details

Biosynthetic class(es):

Gene cluster description

methylenomycin (BGC0000914). Gene Cluster 1. Biosynthetic class = Other. GenBank AL589148, positions 231676-251017. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

Literature references

1. O'Rourke S et al. (2009) Extracellular signalling, translational control, two repressors and an activator all contribute to the regulation of methylenomycin production in Streptomyces coelicolor. Mol Microbiol 71(3):763-78. doi: 10.1111/j.1365-2958.2008.06560.x. Epub
2. Corre C et al. (2008) 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining. Proc Natl Acad Sci U S A 105(45):17510-5. doi:
3. Bentley SD et al. (2002) Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature 417(6885):141-7. doi: 10.1038/417141a.
4. Redenbach M et al. (1998) Cloning and physical mapping of the EcoRI fragments of the giant linear plasmid SCP1. J Bacteriol 180(10):2796-9.