BGC0000914: methylenomycin A biosynthetic gene cluster from Streptomyces coelicolor A3(2)
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Location: 231,676 - 251,017 nt. (total: 19,342 nt).
This entry is originally from NCBI GenBank AL589148.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000914
Short description methylenomycin A biosynthetic gene cluster from Streptomyces coelicolor A3(2)
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
AL589148.1
231676 - 251017
via
Compounds
  • methylenomycin A
Species Streptomyces coelicolor A3(2) [taxonomy]
References
Chemical products information
methylenomycin A Evidence:
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C9H10O4
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAC36752.1
  • mmyF
 231676 - 232200 (-) putative oxidoreductase, MmyF
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    • CAC36753.1
    • mmyY
    		 232231 - 232692 (-) hypothetical protein, MmyY
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      • CAC36754.1
      • mmyB
      		 232923 - 233864 (+) putative DNA-binding protein, MmyB
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        • CAC36755.1
        • mmyQ
        		 233951 - 234604 (+) hypothetical protein, MmyQ
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          • CAC36756.1
          • mmyE
          		 234674 - 235837 (+) putative enoyl reductase, MmyE
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            • CAC36757.1
            • mmyD
            		 236410 - 237429 (+) hypothetical protein, MmyD
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              • CAC36758.1
              • mmyX
              		 237541 - 238245 (+) putative ATP/GTP-binding protein, MmyX
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                • CAC36759.1
                • mmyC
                		 238242 - 239240 (+) putative acyl carrier protein synthase, MmyC
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                  • CAC36760.1
                  • mmyA
                  		 239304 - 239552 (+) putative acyl carrier protein, MmyA
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                    • CAC36761.1
                    • mmyP
                    		 239676 - 240374 (+) hypothetical protein, MmyP
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                      • CAC36762.1
                      • mmyK
                      		 240371 - 240991 (+) putative ATP/GTP-binding protein, MmyK
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                        • CAC36763.1
                        • mmr
                        		 241054 - 242481 (-) methylenomycin A resistance protein, Mmr
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                          • CAC36764.1
                          • mmyJ
                          		 242698 - 243033 (+) hypothetical protein, MmyJ
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                            • CAC36765.1
                            • mmyG
                            		 242996 - 244177 (-) putative oxidoreductase, MmyG
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                              • CAC36766.1
                              • mmyO
                              		 244260 - 245381 (-) putative monooxygenase, mmyO
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                                • CAC36767.1
                                • mmyT
                                		 245412 - 246221 (-) putative thioesterase, MmyT
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                                  • CAC36768.1
                                  • mmfR
                                  		 246362 - 247006 (-) putative 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acid-dependent transcriptional regulator (TetR-family), MmfR
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                                    • CAC36769.1
                                    • mmfL
                                    		 247201 - 248262 (+) 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acid biosynthesis protein, MmfL
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                                      • CAC36770.1
                                      • mmfH
                                      		 248259 - 249461 (+) putative oxidoreductase involved in 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acid biosynthesis, MmfH
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                                        • CAC36771.1
                                        • mmfP
                                        		 249458 - 250255 (+) putative phosphatase involved in 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acid biosynthesis, MmfP
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                                          • CAC36772.1
                                          • mmyR
                                          		 250406 - 251017 (+) putative 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acid-dependent transcriptional regulator (TetR-family), MmyR
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                                            Biosynthesis information
                                            Annotation changelog

                                            Entry version: 4

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-10-07
                                            Update chemical activity to schema version 2.11
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 3

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-09-15
                                            Updated bioactivity data
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 2

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2019-10-16
                                            Migrated from v1.4
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            2019-10-16
                                            Updated compound(s) information (NPAtlas curation)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 1

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2015-06-12
                                            Submitted
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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