BGC0000915: mitomycin biosynthetic gene cluster from Streptomyces lavendulae
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Location: 1 - 63,728 nt. (total: 63,728 nt).
This entry is originally from NCBI GenBank AF127374.2.

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core biosynthetic genes
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resistance
TTA codons
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General
Compounds
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KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000915
Short description mitomycin biosynthetic gene cluster from Streptomyces lavendulae
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Other (Aminocoumarin)
Loci NCBI GenBank: AF127374.2
Compounds
  • mitomycin
Species Streptomyces lavendulae [taxonomy]
References
Chemical products information
mitomycin
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C15H18N4O5
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAD28446.1
123 - 1367 (+) unknown
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  • AAD28447.1
1428 - 1958 (+) LinA-like
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  • AAD28448.1
2006 - 3229 (+) cytochrome P450 hydroxylase
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  • AAD28449.1
3226 - 4458 (+) cytochrome P450 hydroxylase
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  • AAD28450.1
4552 - 5658 (+) unknown
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  • AAD28451.1
5992 - 6849 (+) unknown
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  • AAD28452.1
  • mitT
6854 - 7666 (-) MitT
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  • AAD28453.1
  • mitS
7895 - 8842 (+) MitS
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  • AAD28454.1
  • mitR
8916 - 10460 (+) MitR
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  • AAD28455.1
  • mitQ
10607 - 11101 (+) MitQ
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  • AAD28456.1
  • mitP
11157 - 12188 (+) MitP
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  • AAD28457.1
  • mitO
12193 - 12633 (+) MitO
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  • AAD28458.1
  • mitN
12700 - 13527 (-) MitN
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  • AAD28459.1
  • mitM
13533 - 14384 (-) MitM
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  • AAD28460.1
  • mitL
14432 - 15994 (-) MitL
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  • AAD28461.1
  • mitK
15999 - 17039 (-) MitK
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  • AAD28462.1
  • mitJ
17036 - 17743 (-) MitJ
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  • AAD28463.1
  • mitI
17734 - 18606 (-) MitI
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  • AAD28464.1
  • mitH
18732 - 19880 (-) MitH
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  • AAD28465.1
  • mitG
19877 - 21091 (-) MitG
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  • AAD32718.1
  • mitF
21118 - 21891 (-) MitF
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  • AAD32719.1
  • mitE
21888 - 24011 (-) MitE
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  • AAD32720.1
  • mitD
24169 - 25320 (-) MitD
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  • AAD32721.1
  • mitC
25360 - 26142 (-) MitC
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  • AAD32722.1
  • mitB
26139 - 26957 (-) MitB
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  • AAD32723.1
  • mitA
27091 - 28257 (-) MitA
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  • AAD32724.1
  • mmcA
28969 - 30513 (+) MmcA
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  • AAD32725.1
  • mmcB
30595 - 30876 (+) MmcB
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  • AAD32726.1
  • mmcC
30935 - 32347 (+) MmcC
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  • AAD32727.1
  • mmcD
32347 - 34182 (+) MmcD
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  • AAD32728.1
  • mmcE
34169 - 35248 (+) MmcE
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  • AAD32729.1
  • mmcF
35262 - 35699 (+) MmcF
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  • AAD32730.1
  • mmcG
35789 - 36322 (-) MmcG
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  • AAD32731.1
  • mmcH
36350 - 37114 (-) MmcH
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  • AAD32732.1
  • mmcI
37206 - 38000 (+) MmcI
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  • AAD32733.1
  • mmcJ
38032 - 38856 (-) MmcJ
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  • AAD32734.1
  • mmcK
39063 - 40445 (+) MmcK
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  • AAD32735.1
  • mmcL
40448 - 41983 (-) MmcL
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  • AAD32736.1
  • mmcM
42081 - 43499 (-) MmcM
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  • AAD32737.1
  • mmcN
43595 - 44782 (-) MmcN
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  • AAD32738.1
  • mmcO
44779 - 46203 (-) MmcO
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  • AAD32739.1
  • mrd
46645 - 47037 (-) Mrd
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  • AAD32740.1
  • mmcP
47219 - 48550 (-) MmcP
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  • AAD32741.1
  • mmcQ
48759 - 49130 (-) MmcQ
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  • AAD32742.2
  • mmcR
49634 - 50683 (+) MmcR
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  • AAD32743.1
  • mmcS
50734 - 52374 (+) MmcS
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  • AAD32744.1
  • mmcT
52418 - 54124 (+) MmcT
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  • AAD32745.1
  • mmcU
54121 - 54603 (+) MmcU
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  • AAD32746.1
  • mmcV
54600 - 55559 (+) MmcV
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  • AAD32747.1
  • mct
55658 - 57112 (+) Mct
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  • AAD32748.1
  • mmcW
57143 - 57634 (+) MmcW
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  • AAD32749.1
  • mmcX
57772 - 59013 (+) MmcX
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  • AAD32750.1
  • mmcY
59216 - 60031 (-) MmcY
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  • AAD32751.1
60301 - 60720 (+) unknown
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  • AAD32752.1
60850 - 63660 (+) unknown
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: RIBLHRV4YSJAGJ5EVZV4GS2Z, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Linked new NPAtlas id for mitomycin (npatlas:NPA020531)
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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