BGC0000921 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000921 (Pseudomonas putida)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like	1	15,751	promysalin	other:shikimate-derived+PKS+NRPS:Type I	100%

BGC0000921 - Region 1 - NRPS-like

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Location: 1 - 15,751 nt. (total: 15,751 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 15,752
Label		BGC0000921

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000921	1.00	Other (Shikimate-derived), Polyketide, NRP	promysalin	Pseudomonas putida
BGC0001925	0.31	Alkaloid	altemicidin, SB-203207, SB-203208	Streptomyces sp.
BGC0000343	0.30	NRP	enterobactin	Pseudomonas sp. J465
BGC0002474	0.26	NRP	agrobactin	Agrobacterium tumefaciens
BGC0001444	0.24	Other (shikimate derived)	caboxamycin	Streptomyces sp. NTK 937
BGC0002020	0.23	Saccharide, NRP	photolose	Photorhabdus laumondii subsp. laumondii TTO1
BGC0002225	0.23	Terpene	aculene A, aculene B, aculene C, asperaculane A, asperaculane B, aculene D	Aspergillus aculeatus ATCC 16872
BGC0002493	0.22	NRP	parabactin	Paracoccus denitrificans PD1222
BGC0002711	0.22	Polyketide	nostovalerolactone, 9-dehydronostovalerolactone	Nostoc punctiforme PCC 73102
BGC0001739	0.22	Other	phosphonoacetic Acid	Streptomyces sp. NRRL F-525

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000921	1.00	Other (Shikimate-derived), Polyketide, NRP	promysalin	Pseudomonas putida
BGC0001925	0.64	Alkaloid	altemicidin, SB-203207, SB-203208	Streptomyces sp.
BGC0000343	0.64	NRP	enterobactin	Pseudomonas sp. J465
BGC0002474	0.59	NRP	agrobactin	Agrobacterium tumefaciens
BGC0001444	0.57	Other (shikimate derived)	caboxamycin	Streptomyces sp. NTK 937
BGC0002020	0.56	Saccharide, NRP	photolose	Photorhabdus laumondii subsp. laumondii TTO1
BGC0002225	0.56	Terpene	aculene A, aculene B, aculene C, asperaculane A, asperaculane B, aculene D	Aspergillus aculeatus ATCC 16872
BGC0002493	0.56	NRP	parabactin	Paracoccus denitrificans PD1222
BGC0002711	0.55	Polyketide	nostovalerolactone, 9-dehydronostovalerolactone	Nostoc punctiforme PCC 73102
BGC0001739	0.55	Other	phosphonoacetic Acid	Streptomyces sp. NRRL F-525

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 15751:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Pro)

Direct lookup in NORINE database: strict or relaxed

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NRPS/PKS substrate predictions

ppgJ

Search NORINE for peptide: strict or relaxed

AMP-binding (15..416): Pro

nrpys: Pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)
Small clusters prediction:: pro (Pro)
Single AA prediction:: pro (Pro)

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFVAHVVK
Nearest Stachelhaus code(s):: Pro DVQFVAHVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ppgM

AMP-binding (29..429): X

nrpys: Sal

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ALPSQGILCK
Nearest Stachelhaus code(s):: Sal ALPSQGVLNK (74% 8Å match)
Stachelhaus code match:: 80% (moderate)