BGC0000932: tropodithietic acid biosynthetic gene cluster from Phaeobacter inhibens DSM 17395
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Location: 88,772 - 108,389 nt. (total: 19,618 nt).
This entry is originally from NCBI GenBank CP002977.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000932
Short description tropodithietic acid biosynthetic gene cluster from Phaeobacter inhibens DSM 17395
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
CP002977.1
88772 - 108389
via
Compounds
  • tropodithietic acid
  • hydroxytropodithietic acid
Species Phaeobacter inhibens DSM 17395 [taxonomy]
References
Chemical products information
tropodithietic acid Evidence:
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C8H4O3S2
Chemical database entries
PubCHEM
hydroxytropodithietic acid Evidence:
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C8H4O4S2
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • PGA1_262p00800
  • AFO93362.1
  • paaZ
 88772 - 90904 (+) phenylacetic acid degradation protein PaaZ
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    • PGA1_262p00810
    • AFO93363.1
    • tdaF
    		 90939 - 91508 (+) putative flavoprotein, HFCD family
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      • PGA1_262p00820
      • AFO93364.1
      		 91588 - 92028 (-) hypothetical protein
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        • PGA1_262p00830
        • AFO93365.1
        		 92033 - 93094 (-) hypothetical protein
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          • PGA1_262p00840
          • AFO93366.1
          		 93186 - 94511 (-) hypothetical protein
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            • PGA1_262p00850
            • AFO93367.1
            		 94642 - 96099 (-) putative sodium dependent symporter
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              • PGA1_262p00860
              • AFO93368.1
              		 96397 - 96855 (+) hypothetical protein
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                • PGA1_262p00870
                • AFO93369.1
                		 96898 - 98499 (+) ABC transporter, extracellular solute-binding protein
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                  • PGA1_262p00880
                  • AFO93370.1
                  		 98504 - 99547 (+) ABC transporter, integral inner membrane component
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                    • PGA1_262p00890
                    • AFO93371.1
                    		 99548 - 100357 (+) ABC transporter, integral inner membrane component
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                      • PGA1_262p00900
                      • AFO93372.1
                      		 100354 - 101850 (+) ABC transporter, ATP-binding protein
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                        • PGA1_262p00910
                        • AFO93373.1
                        		 101847 - 102404 (-) putative cation transort protein
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                          • PGA1_262p00920
                          • AFO93374.1
                          		 102488 - 103174 (-) conserved hypothetical protein, peptidase M23-like protein
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                            • PGA1_262p00930
                            • AFO93375.1
                            		 103171 - 103752 (-) hypothetical protein
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                              • PGA1_262p00940
                              • AFO93376.1
                              • tdaE
                              		 103793 - 104986 (-) acyl-CoA dehydrogenase TdaE
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                                • PGA1_262p00950
                                • AFO93377.1
                                • tdaD
                                		 105010 - 105426 (-) thioesterase superfamily protein TdaD
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                                  • PGA1_262p00960
                                  • AFO93378.1
                                  • tdaC
                                  		 105464 - 106066 (-) prephenate dehydratase TdaC-like protein
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                                    • PGA1_262p00970
                                    • AFO93379.1
                                    • tdaB
                                    		 106586 - 107284 (-) putative beta etherase TdaB
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                                      • PGA1_262p00980
                                      • AFO93380.1
                                      • tdaA
                                      		 107499 - 108389 (-) transcriptional regulator, LysR family
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                                        Biosynthesis information
                                        Annotation changelog

                                        Entry version: next

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2024-04-23
                                        MIBiG v4 annotathon
                                        • (ID: 6QCS3DG25AGWNE77BXBLFKVB)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 4

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2022-10-07
                                        Update chemical activity to schema version 2.11
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 3

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2022-09-15
                                        Add new compound structure (SMILES) for tropodithietic acid
                                        • (ID: 5UL74VURKJ25VSPPPO3H2NYB)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        2022-09-15
                                        Linked new PubChem id for tropodithietic acid (pubchem:44632924)
                                        • (ID: FXGHY3FQ6PUVIIQ6EB3CJFGW)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        2022-09-15
                                        Add new compound: hydroxytropodithietic acid
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        2022-09-15
                                        Merged annotations from duplicate entry BGC0001362
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        2022-09-15
                                        Updated bioactivity data
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 2

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2019-10-16
                                        Migrated from v1.4
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 1

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2015-06-12
                                        Submitted
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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