LOCUS       BGC0000935             29897 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptomyces antibioticus strain Tu 2706 plasmid esmeraldin
            biosynthetic gene cluster, complete sequence.
ACCESSION   BGC0000935
VERSION     BGC0000935
KEYWORDS    .
SOURCE      Streptomyces antibioticus
  ORGANISM  Streptomyces antibioticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 14:27:07
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 29897
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..29897
                     /db_xref="taxon:1890"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces antibioticus"
                     /plasmid="unnamed"
                     /strain="Tu 2706"
     misc_feature    1..29897
                     /note="esmeraldin biosynthetic gene cluster"
     subregion       1..29897
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="other, PKS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..29897
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            152..1624
                     /gene="esmT3"
     CDS             152..1624
                     /codon_start=1
                     /gene="esmT3"
                     /note="integrin-like protein"
                     /product="EsmT3"
                     /protein_id="AFB35615.1"
                     /transl_table=11
                     /translation="MGIRRLAVSTAVVAALTGTFGVPLAAGTASAAGGATTVREDFNGD
                     GYQDVAVSAPAATVGGHAWAGYLTVTYGSANGLDTARTTVVTQDTAGVPGAAGDNAVFG
                     YAMVPRDLDGDGLTDLAVTTREYRPEENVSGSVIVLWGRTTGISGQDAVRVGAPANAEV
                     GTGITAGDFDGDGHVDLFMGNGDDYDYRSVLYGPFDRSGTPAREQDLMVFSTDNTLSST
                     AAGDFDGDGIEDLATFYVYENHAEGGKLWLGTEDGLSTVPQRLPSASATAVADFDRDGY
                     ADLATRVFPGGDTEMVDDPGTVKIYYGSPAGPSQTRTRTFTQESAGVPGASEKNDHFGA
                     RLSAGDANGDGYPDLAVGVPGEAIGSVAKAGATVLLKGGGAGLTGTGAQAFHQDTPDVP
                     GVAEKNDVFGASLRLLDVTGDGKADLTVSAPGEDLGTVRNGGAVWLLRGAAAGLTASKS
                     AAHNPVDLGTPVANAQYGWDLGGDNGPGVAIP"
     gene            1695..2423
                     /gene="esmT4"
     CDS             1695..2423
                     /codon_start=1
                     /gene="esmT4"
                     /gene_functions="regulatory (smcogs) SMCOG1215:TetR family
                     transcriptional regulator (Score: 120.8; E-value: 1.3e-36)"
                     /gene_kind="regulatory"
                     /note="transcriptional regulator"
                     /product="EsmT4"
                     /protein_id="AFB35616.1"
                     /transl_table=11
                     /translation="MRTMQYVSGKRAAEDGWRERKKRATRAALVESAVRLAAERGLESV
                     TVDAISAAAGVSARTFFNYFDSRDDVFVLIGAESSARVRRAVLDAPRALSPLEALRDAM
                     AEELQEVEQQTELWRLYAEVLDRTPALLARSLGAYMADEIGLAEAVAERIGGPSSPLTG
                     TGTDTGTGPDGPSEDERRRALDLYPRLLAAVGATAGRVAVEHWCVRQDGARFADVFREV
                     FEQLAAGLPQPPEPTTPGRR"
     gene            2551..3999
                     /gene="esmT5"
     CDS             2551..3999
                     /codon_start=1
                     /gene="esmT5"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 283.5; E-value:
                     3.8e-86)"
                     /gene_kind="transport"
                     /note="putative exporter"
                     /product="EsmT5"
                     /protein_id="AFB35617.1"
                     /transl_table=11
                     /translation="MTSPAAPEEASPTAMSHRQIMQAMSGLMAGMFVAILAGTVVANAL
                     PRIIADLGASQSSYTWVVTAELLAMTATVPLWGKLADLYDQKLLLQLSLCMFVVGSLLA
                     GFSHDVGLLIFSRVAQGIGAGGLTALAQVVMAAVIPPRRLGKYAGIFGAVFAVGTVAGP
                     LIGGVLVDTSWLGWRWCFFIGVPFALLAIVLLQRTLKLPTVRREAQIDFLGAFLIVAGV
                     CALLIWVSLAGNEFDWAPWQTAALTGGGLLALVAALYVESRVAEPIIPLGIFRNRTVSL
                     TTLSSLFVGVAMFGGTVFLSQYFQVSLGKSPTVAGLMSLPMILGLLVSSTVAGQIISAT
                     GRWKIYLVLAAQNDVPAAELGAATSVLSFFRSMGGTIGTSVLGAILANRVASEMTKGLQ
                     DAGAPAGSTEGGAHSVPDMTKLPAPMREIVEHAYGVATGDLFLVATPFALLALVAVLFI
                     KEKPLKDTSGMERLAEEKEPSAAR"
     gene            4154..4654
                     /gene="esmA1"
     CDS             4154..4654
                     /codon_start=1
                     /gene="esmA1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phenazine: phzB"
                     /gene_kind="biosynthetic"
                     /note="AOCHC dimerization"
                     /product="EsmA1"
                     /protein_id="AFB35618.1"
                     /sec_met_domain="phzB (E-value: 2.8e-77, bitscore: 250.5,
                     seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGASSMSDAKQQGFDDHAELRRINRETVEKYMHTTGQDRLERHLL
                     FTEDGSGGLWTTDTGEPIVIRGRDRLGEHAVWSLKCFPDWVWYNIEVFETQDPNRFWVE
                     CDGKGKILFPGYPEGYYRNHFLHSFLLENGKVVQNREFMNPFEQLRALGIPVPEIKREG
                     IPT"
     gene            4703..5035
                     /gene="esmH1"
     CDS             4703..5035
                     /codon_start=1
                     /gene="esmH1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) thio_amide"
                     /gene_kind="biosynthetic-additional"
                     /note="hypothetical"
                     /product="EsmH1"
                     /protein_id="AFB35619.1"
                     /sec_met_domain="thio_amide (E-value: 2.2e-19, bitscore:
                     60.1, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAMIAWWALDDSDQTIDSLRDFLRDEAVDAWALVRGMPLKFWIA
                     DRENNRWGAVMLWESAEAAAPPLPRSPAELIGYPPTHRTWFDIEAVIEGIHSLPPLAGL
                     GLALDT"
     gene            5068..5703
                     /gene="esmA2"
     CDS             5068..5703
                     /codon_start=1
                     /gene="esmA2"
                     /note="penazine-1,6-dicarboxylic acid formation"
                     /product="EsmA2"
                     /protein_id="AFB35620.1"
                     /transl_table=11
                     /translation="MSVTPQKIVPKSADALSESGTPPDDPIELFRAWLADAAENGVREP
                     GALALATADAQGRASNRIIQLGPLTSDGFVFATHDISPKARDMEATAWASAVLYWRETD
                     QQTVLSGRVTRLPDVESDELWRVRSIDAQAMTTVSRQSEPLDDAAALRAEVGKLAEAGK
                     PLPRPARFVGYHLAPESVEFWHTGKDRLHKRLLYSRVAGGWSVTRLQP"
     gene            complement(5783..7204)
                     /gene="esmB2"
     CDS             complement(5783..7204)
                     /codon_start=1
                     /gene="esmB2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /note="functions with EsmB1"
                     /product="EsmB2"
                     /protein_id="AFB35621.1"
                     /sec_met_domain="Aldedh (E-value: 1.4e-14, bitscore: 44.1,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQSPPQNQNQNQDKAPAPADVVTLDALGPNGPYASRSHQEIKDV
                     AGNPAARLGLVPTLFVTRAMSALRRATPLPVDERIAAIARAGELFATATLGGLSVSAYE
                     HRVSRVSGLPVPVVREATRTAAHRAAHVYDSVQYARPQGSAGDWRDPLTRTGRAVWTRR
                     GEVLAVHVSGVHPGAHSLWLEALALGYRVAVRPTRREPYTAHRLVTALWAAGFGTDHVV
                     LLPTEQEPGEALLRGADLAYGGDDVIRKYAGESTVLSQEPGRSKVLLTAGADWRDHLDM
                     IVDSVAHHGGTGCVNATAVLVEGDPAPVAEALAARLAALPSLPPEDEKAVLPVQARMPA
                     RALERYVLSNAAETRAWLGGDGFVDELGDGSAVVRPTVHQLDSPTAPQADLELPFPCVW
                     VAPWTPEAGLEALRDTLVLTVVTEDEHLIDTLVNEPTIGNLYVGRHPTHWTDIGMPHDG
                     YLSDFLMRTKTVIRG"
     gene            complement(7204..8301)
                     /gene="esmB1"
     CDS             complement(7204..8301)
                     /NRPS_PKS="Domain: AMP-binding (72-315). E-value: 1.3e-10.
                     Score: 32.3. Matches aSDomain:
                     nrpspksdomains_esmB1_AMP-binding.1"
                     /codon_start=1
                     /gene="esmB1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_kind="biosynthetic-additional"
                     /note="phenazine-1,6-dicarboxylic acid adenylase"
                     /product="EsmB1"
                     /protein_id="AFB35623.1"
                     /sec_met_domain="AMP-binding (E-value: 3.7e-10, bitscore:
                     29.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSREANPVLDLPFDVRPDPDEFIQAAMDWHFSPETGSPYWLERAK
                     KLDFDPRADVTSHQDLQLFPNVVNELRDVPAQDLVPRGYDAPDVVGVYESGGTTGAPKR
                     VVCLADWMDRVVAWSVANLDAHGFPRGANWLGVTPTGPHVVGELFSRSAAAHGSLSFPV
                     DLDPRWVKRLIAEGKTDQADAYAEHVVDQAAFVLRTQDIGVMAITPPLLERLTRRDELV
                     DLVNRKVRAIRWGGTQMDADSRYLYRTEVFPDTTLYGHYGSTMILGIAGQRPGLGDDDP
                     CVFDTFSPYITFSVVNPETRKTVPYGERGRVVMNHVSKSLFLPNNLERDLATRIAPLPG
                     QIGDAVADIAPVTHFEDEAVIEGVY"
     aSDomain        complement(7357..8085)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_esmB1_AMP-binding.1"
                     /evalue="1.30E-10"
                     /label="esmB1_AMP-binding.1"
                     /locus_tag="esmB1"
                     /protein_end="315"
                     /protein_start="72"
                     /score="32.3"
                     /tool="antismash"
                     /translation="DVPAQDLVPRGYDAPDVVGVYESGGTTGAPKRVVCLADWMDRVVA
                     WSVANLDAHGFPRGANWLGVTPTGPHVVGELFSRSAAAHGSLSFPVDLDPRWVKRLIAE
                     GKTDQADAYAEHVVDQAAFVLRTQDIGVMAITPPLLERLTRRDELVDLVNRKVRAIRWG
                     GTQMDADSRYLYRTEVFPDTTLYGHYGSTMILGIAGQRPGLGDDDPCVFDTFSPYITFS
                     VVNPETRKTVPYGERGRVVMN"
     gene            complement(8314..9399)
                     /gene="esmT1"
     CDS             complement(8314..9399)
                     /codon_start=1
                     /gene="esmT1"
                     /note="transcriptional regulator"
                     /product="EsmT1"
                     /protein_id="AFB35624.1"
                     /transl_table=11
                     /translation="MIRRTGTSKSLPENPESTVEPSSEETETAPVNLLIPGYSPRIGGE
                     ITSHVQALAETEGTLPPIIVHRPSMRVIDGMHRVRSAILRGQQTIRVRYFDGTEQDAFV
                     LAVRLNVKHGLPLTLAERRRAAARIVVSHAQLSDRAIASLTGLSGKTVGEIRKRTAEGA
                     HQPLARVGRDGRTRPLNTERGRRLAAEYLSANPGGSLREVSRVAGISPETVRDVRDKLS
                     RGEDPIPVRQRFLPAAEEAGGSAAAPARTEKDGARRFGRPAAVHRVPADGRHALNVLRK
                     DPSLRFTEAGRVLLRLMDPHILFADRREQLIKDLPEHTLGMLSEVARQYAASWSDIAGA
                     LEERARQTALNPQSAAEIRIS"
     gene            9770..10507
                     /gene="esmA3"
     CDS             9770..10507
                     /codon_start=1
                     /gene="esmA3"
                     /note="DHHA isomerase"
                     /product="EsmA3"
                     /protein_id="AFB35622.1"
                     /transl_table=11
                     /translation="MQKIAREMNLSEVTFVLPAEKGGDARIRIFTPVNELPFAGHPMLG
                     TAAVLGDTFEGDRLLLETAMGVIPFDLDRENGRVTSVRMQQPVPVWEPYEHADELLEGL
                     GLKSSTLPVEAYRNGPRHVFVGLEDVAALSAVRPDLRVLARFPDMAANCFAPADGHWRS
                     RMFSPAYGVAEDAATGSAAGPLAIHVARHGLGRFGQRVEILQGVEMGRPSTMIARAEGT
                     ADRITSVEVGGAAVVVAEGTLRI"
     gene            10563..13358
                     /gene="esmT2"
     CDS             10563..13358
                     /codon_start=1
                     /gene="esmT2"
                     /gene_functions="regulatory (smcogs) SMCOG1149:LuxR family
                     transcriptional regulator (Score: 132.8; E-value: 2.2e-40)"
                     /gene_kind="regulatory"
                     /note="quorum sensing"
                     /product="EsmT2"
                     /protein_id="AFB35625.1"
                     /transl_table=11
                     /translation="MMSDDTVTEWPMAGRNTELDRIEAAVARGHGALLTGVPGVGKSRL
                     LRASLRRAAAQGAEVRLVSGAGMCGAEVSSLFTGWGSASGREQPDASRHLLDETFPSRR
                     TPSADGLQGQFVLGLDDAHCLAPGFAARLRAGVAEGRLTLVAAVRAGVPAPDGIHRLWV
                     ERLVERVEIGELDRSAAADVVHARLGGHVSAAAQERLWQLTHGNALLLTELADSALADG
                     SLRREDGTWLWDGLNGRPAGRLTDMVHLRLGHLSPDERRLVQMIALAEPLEAELSAVAE
                     LAHAVEALDSRGLITAELSGLRLRLRLAYPLYRPVLVSSLPELTGLRLRRRLADALEDT
                     GLRRDDDVLRMVVLRIDAGQLPCAEQLQCAARTALRRLRFALAERLCLLALAASDADVP
                     GLTLLRGRALEGQGRQAEAETLFAAVSAADAPTAPAVWAEAVQARSENLAWGLHLVQDA
                     VTVLDEAVATAPEADLGPLQGTRTVMMLLGDRLEEAAAMGETVLAEPRDPAVVQRVLPP
                     AAFAHNELGDAVGALSLLQRCRPEPETWSDEARLAHQLVAACAALQTGAVAVAAAVLDG
                     LPAQDADDDRTGELWTASVRARLYRSSGRFTEGIALLRRVSAMPDTRDWLTTRAWRLAQ
                     MAGALAEVGEHAEAMRILVEVRAEESGTVRYPLAADGVAMERALVLAHVGDFAGALHDA
                     LELGERAAAAGRAFQALGALHLAARIGEARAVAERASDLAEHLDSGLAELQAEHVRALA
                     DADGDALSELAERFELSGLLPLAAEASAQACRAHQAAGRHRKSRAARSVCQELLQRFGG
                     TLPVWAALDAQGPEQSAELTGREREVAALAASGLSNQDVADRLGVSVRTVENHLHRAYG
                     KLGVTTRADLARHLDSRLPTDGFGAAPAPGRGRAPRALDPAPPTPGTPGRRPGRTGAAT
                     P"
     gene            complement(13803..15731)
                     /gene="esmA5"
     CDS             complement(13803..15731)
                     /codon_start=1
                     /gene="esmA5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 322.5; E-value:
                     9.4e-98)"
                     /gene_kind="biosynthetic-additional"
                     /note="ADIC synthase"
                     /product="EsmA5"
                     /protein_id="AFB35626.1"
                     /transl_table=11
                     /translation="MTARDPAGSLLDRLTGGTPPPSFALLHRPRASGAGHIDLLAGDVS
                     EVGSTADIPLPPEGGRDRHEVLALLPFRQIAERGYEHNDDGEPLLVMKVGEQAVARTDE
                     VLARLPDLPIEVRDGGFDIDDEEYAATVRRILTDEIGTGAGANFVIKRAFTARLANWSA
                     QTALTLFGRLLRHTSGAHWTFLIRVGGRTFIGASPERHLTLDGGTAVMNPISGTYRYPP
                     SGPTLKGALEFLGDRKEANELYMVVDEELKMMCRVCDGGARVVGPRLREMPHLAHTEYF
                     IEGEVTRDIREVVRETLFAPTVTGSPLESACRVIAKYENEGRGYYAGVVALLGRDAGGL
                     RRLDSAILIRTADIDRTGRLRLGVGSTLVRDSDPRAEAEETRAKASGLLAALYADPGTG
                     ADPARPAVGVPRLGDLPEVADALAARNVPMADFWRQPPAARRGGSSRLAGRRALLIDAE
                     DTFTAMGAAMMSELGLDVSVHRFDEEYRFEGHDLVVVGPGPGDPRDTSHPKNAHLRAVT
                     RRLLGTDIPFLSICLGHQALSGVLGLELVRKEVPNQGVQREIDFFGRREAVYFYNTFAA
                     VSPQDSFPGPPTRPGPVEVCRDPVDHEVHGMRGQGFASVQFHPASVMSRDGAAILSRMI
                     TNLLPTP"
     gene            complement(15728..16396)
                     /gene="esmA4"
     CDS             complement(15728..16396)
                     /codon_start=1
                     /gene="esmA4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:isochorismatase (Score: 292.5; E-value: 3.8e-89)"
                     /gene_kind="biosynthetic-additional"
                     /note="DHHA synthase"
                     /product="EsmA4"
                     /protein_id="AFB35627.1"
                     /transl_table=11
                     /translation="MAAPSIPEIAPYPMPEAADLPENTAHWTVDPRRAVLLVHDMQHFF
                     LRPFPAGRPPVTDLVGHVVRLREAAVAAGVPVAYTAQPGDMTAEQRGLLKDFWGPGMSA
                     DPEQRGVPDELAPGPDDVVLDKWRPSAFFRTPLLDLLRERGRDQLVLCGVYAHVGILQT
                     ACEAFAHDIQTFLVGDAVADFSARDHRMAVEYAAARCSVVVPTDTVVNALGRVVTGTAL
                     "
     gene            complement(16422..16673)
                     /gene="esmD3"
     CDS             complement(16422..16673)
                     /NRPS_PKS="Domain: PP-binding (9-75). E-value: 1.7e-12.
                     Score: 39.6. Matches aSDomain:
                     nrpspksdomains_esmD3_PP-binding.1"
                     /codon_start=1
                     /gene="esmD3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /note="6-methylsalicylyl carrier protein"
                     /product="EsmD3"
                     /protein_id="AFB35628.1"
                     /sec_met_domain="PP-binding (E-value: 7.5e-13, bitscore:
                     39.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADEPVSTSDQVRTAVAALIGTAPHDIPGDANLVFLGLGSLDVMR
                     LSSRWRREGLPVEFEVLTADPTIDSWARHLDSLRPRSN"
     aSDomain        complement(16449..16646)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_esmD3_PP-binding.1"
                     /evalue="1.70E-12"
                     /label="esmD3_PP-binding.1"
                     /locus_tag="esmD3"
                     /protein_end="75"
                     /protein_start="9"
                     /score="39.6"
                     /tool="antismash"
                     /translation="DQVRTAVAALIGTAPHDIPGDANLVFLGLGSLDVMRLSSRWRREG
                     LPVEFEVLTADPTIDSWARHL"
     gene            complement(16712..18415)
                     /gene="esmD2"
     CDS             complement(16712..18415)
                     /NRPS_PKS="Domain: AMP-binding (31-446). E-value: 2.6e-81.
                     Score: 265.1. Matches aSDomain:
                     nrpspksdomains_esmD2_AMP-binding.1"
                     /codon_start=1
                     /gene="esmD2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     447.8; E-value: 6.6e-136)"
                     /gene_kind="biosynthetic-additional"
                     /note="6-MSA adenylase"
                     /product="EsmD2"
                     /protein_id="AFB35629.1"
                     /sec_met_domain="AMP-binding (E-value: 7.2e-92, bitscore:
                     298.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDGCTPWPDEYAERYRAQGHWSGETLIDVLESSAARHGSRTALV
                     QGDRRVSYDELVRRSRWAAAGFRELGIAADDRVVVQLPNVAEFVVVCFALFRLGAKPVF
                     ALPSHRASEIRHLVDISGAVGYVLPGVHRGFDHPALGRRVRDETGTLRHLFTLDDAAAD
                     DDMIALSAVEAAGAAADPSGSASFPAPDPADVAFFLLSGGTTALPKLIPRTHDDYVYMM
                     RAAVEAIRLTENDVYLAVLPVEFNFTFGCPGVIGTLLSGGTAVLASDATPELCFPVVER
                     EGVTVTSVGPSVVQLWLDAAEWMKPDLSSVRALQIGGSKLHRDLAERIRPELGCGIQQV
                     FGMAEGLICFTREGDSEEDLLTTQGLPISPADEMKIVDDKDQEVPAGTIGELLTRGPYT
                     PRGYYRSPEHNARAFTEDGFYRSGDLARLTPEGRLVIEGRIKDLINRGGEKVSAGEVEG
                     HLETHPAIARAAVVPVPDDYLGERICAYIVPVGAPPSLPEIKAALTERGLAAYKLPDRV
                     EVVDELPLTGLGKIDKKVLAARSRGAATPAASAFLATTHSSGTDPDRPAS"
     aSDomain        complement(17078..18322)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_esmD2_AMP-binding.1"
                     /evalue="2.60E-81"
                     /label="esmD2_AMP-binding.1"
                     /locus_tag="esmD2"
                     /protein_end="446"
                     /protein_start="31"
                     /score="265.1"
                     /tool="antismash"
                     /translation="ESSAARHGSRTALVQGDRRVSYDELVRRSRWAAAGFRELGIAADD
                     RVVVQLPNVAEFVVVCFALFRLGAKPVFALPSHRASEIRHLVDISGAVGYVLPGVHRGF
                     DHPALGRRVRDETGTLRHLFTLDDAAADDDMIALSAVEAAGAAADPSGSASFPAPDPAD
                     VAFFLLSGGTTALPKLIPRTHDDYVYMMRAAVEAIRLTENDVYLAVLPVEFNFTFGCPG
                     VIGTLLSGGTAVLASDATPELCFPVVEREGVTVTSVGPSVVQLWLDAAEWMKPDLSSVR
                     ALQIGGSKLHRDLAERIRPELGCGIQQVFGMAEGLICFTREGDSEEDLLTTQGLPISPA
                     DEMKIVDDKDQEVPAGTIGELLTRGPYTPRGYYRSPEHNARAFTEDGFYRSGDLARLTP
                     EGRLVIEGRIKDLINR"
     CDS_motif       complement(17174..17263)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_esmD2_0001"
                     /evalue="3.10E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="esmD2"
                     /protein_end="414"
                     /protein_start="384"
                     /score="19.6"
                     /tool="antismash"
                     /translation="PAGTIGELLTRGPYTPRGYYRSPEHNARAF"
     gene            complement(18518..19555)
                     /gene="esmD1"
     CDS             complement(18518..19555)
                     /codon_start=1
                     /gene="esmD1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PKS-like: ksIII"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 81; E-value: 1.4e-24)"
                     /gene_kind="biosynthetic"
                     /note="esterification"
                     /product="EsmD1"
                     /protein_id="AFB35630.1"
                     /sec_met_domain="ksIII (E-value: 8.4e-76, bitscore: 245.6,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLENIYLAGVGTYIPELMPVEQAVKAGLYTEEEHRASGMESVAV
                     EDTLGAPDMAIRAAEIAIRRSGHHPDDFASLLHSTTFLQGPHDGWSPSHYILLNTLDRP
                     ISAAVIQQGCNGLMTGIEMAAHRLMASPDKDAALVTGADNFNTPLVDRWRASGLFFMAD
                     SGSAIVVSRRGGFAKVLAVGSVSDPKLEWRHRAEGSLMPPREPSHKLLDFETRVKFWQR
                     KWAEGAPPPGGNFIDLLADVAQRTLAEVGLTMDQVARVTHVGFHHGSLHALYLEPLGID
                     ADRGTWEHSRRIGHASMSDVVIGLEHLWLTRQVNPGDRVLMIGTTPGMEVGCAVVEITR
                     GPEDA"
     gene            complement(19651..20187)
                     /gene="esmA8"
     CDS             complement(19651..20187)
                     /codon_start=1
                     /gene="esmA8"
                     /note="shikimate kinase"
                     /product="EsmA8"
                     /protein_id="AFB35631.1"
                     /transl_table=11
                     /translation="MTGRAPGPAVVLVGPMAVGKTTVGRILAGRLGLPFRDTDADIVAA
                     RARTVADVFAEEGEARFRELERAAVRAALAEHTGVLALGGGAVLDARTRGLLAGGPVVF
                     LDMEPQDAVRRLAAGPVRPLLAVDPEAVWRATSASRRPLYTQVARVVVATGGRTPEGVA
                     DIVLEALAAAPAPGR"
     gene            complement(20199..21383)
                     /gene="esmA7"
     CDS             complement(20199..21383)
                     /codon_start=1
                     /gene="esmA7"
                     /note="chorismate synthase"
                     /product="EsmA7"
                     /protein_id="AFB35632.1"
                     /transl_table=11
                     /translation="MSSLRWLTAGESHGPALVATLEGLPSGVPVTKRMVSDALARRRLG
                     HGRGARMTFERDEVTFLGGVRHGLTLGSPVAVMVANTEWPKWQQVMAADPVAPEVLAGL
                     ARNAPLTRPRPGHADLAGMQKYGFPEARPVLERASARETAARVALGAVARSYLRATAGV
                     EIVSHVVELGAVAAPYGLLPAPRDTARLDADPVRCLDPDTSARMVAAIDGARAEGDTLG
                     GVVEVLAHGVPVGLGSHVHWDRRLDARLAAALMGIQAIKAVELGDGTALARVPGSRAHD
                     EIVPSPDGVRRASGRSGGTEGGLSTGEPLRVRAAMKPIATVPRALATVDVATGDTARAH
                     HQRSDVCAVPAAGIVAEAMVALVLADAVAEKFGGDSVPETRRNVTGFLDHLAVQ"
     gene            complement(21427..22842)
                     /gene="esmA6"
     CDS             complement(21427..22842)
                     /codon_start=1
                     /gene="esmA6"
                     /note="DAHP synthase"
                     /product="EsmA6"
                     /protein_id="AFB35633.1"
                     /transl_table=11
                     /translation="MRSFLKGSPMASGNASARDSLRTYPAAQQPDWPDRSALDAVTRKL
                     ETLPPLVFAGECDRLKDRLAAVALGEAFLLQGGDCAETFDGVRADTTRDKLSTLLQMAV
                     VLSYASSVPVVKVGRLAGQYAKPRSKPTETRDGVVLPVYRGDAVNGFEFTEDSRVPDPA
                     RLLTMYQASVTTLNLVRAFTSGGDANLRQIHDLTRDFVSGSPSGHRYESIADEIDRALR
                     FMHATGGPGGADAEEFFVSHEGLLLDYEAALTRVDTFTGLPYATSGHMLWIGERTRDLS
                     GAHVEYFSRINNPIAVKLGPKADADTVLQLIDRLDPKREPGRLTLVVRMGADKVQDALP
                     PLVEKVTASGAKVAWVCDPMHGNTLEAPSGHKTRRFDDVLDEIRGFFDVHHSLGTHPGG
                     IHVEFTGNDVTECVGGGHEVLFEDLASRYESVCDPRLNRSQSLDLAFLVSEFLGTRERR
                     PARPLSATSGPLV"
     gene            23336..23743
                     /gene="esmB3"
     CDS             23336..23743
                     /NRPS_PKS="Domain: PCP (27-96). E-value: 5.8e-23. Score:
                     72.8. Matches aSDomain: nrpspksdomains_esmB3_PCP.1"
                     /codon_start=1
                     /gene="esmB3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /note="carrier protein"
                     /product="EsmB3"
                     /protein_id="AFB35634.1"
                     /sec_met_domain="PP-binding (E-value: 8.6e-18, bitscore:
                     55.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSQPEPQDSLTDLSGKESPRPSATDTERAIAEIWSEVLEERQVG
                     PEDNFFDLGGHSVLLHLVQDRITEELGRKPSLVDLFTYTTVRALARHLDGDTAGPARSG
                     SAAERAGGRARLQQRARRTRSAARDQGGTGE"
     aSDomain        23417..23623
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_esmB3_PCP.1"
                     /evalue="5.80E-23"
                     /label="esmB3_PCP.1"
                     /locus_tag="esmB3"
                     /protein_end="96"
                     /protein_start="27"
                     /score="72.8"
                     /tool="antismash"
                     /translation="ERAIAEIWSEVLEERQVGPEDNFFDLGGHSVLLHLVQDRITEELG
                     RKPSLVDLFTYTTVRALARHLDGD"
     CDS_motif       23480..23509
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_esmB3_0001"
                     /evalue="2.60E-03"
                     /label="PCP_mC"
                     /locus_tag="esmB3"
                     /protein_end="58"
                     /protein_start="48"
                     /score="11.1"
                     /tool="antismash"
                     /translation="NFFDLGGHSV"
     gene            23736..26510
                     /gene="esmB4"
     CDS             23736..26510
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (15-435). E-value:
                     9.3e-155. Score: 507.5. Matches aSDomain:
                     nrpspksdomains_esmB4_PKS_KS.1"
                     /NRPS_PKS="Domain: PCP (845-911). E-value: 2.9e-18. Score:
                     57.7. Matches aSDomain: nrpspksdomains_esmB4_PCP.1"
                     /codon_start=1
                     /gene="esmB4"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 69.2; E-value:
                     4.6e-21)"
                     /gene_kind="biosynthetic"
                     /note="ketosynthase-acyltransferase-acyl carrier protein"
                     /product="EsmB4"
                     /protein_id="AFB35635.1"
                     /sec_met_domain="hyb_KS (E-value: 6.4e-157, bitscore:
                     513.4, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 3.5e-21, bitscore: 66.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.1e-16, bitscore:
                     51.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDDGLGEPADDAEHIAVIGMAARFPGAEDIGQFWRNLTDGLDTV
                     TRSDPRPVPGGGPTRSYVPARGLLREPEWFDADYFGYSPREARIIDPQHRVLLECAVQA
                     LEHAGHDPARYPGAIGVYGGGTATRYAELARSGADSVSGATDMEILLGNANDYLVTRIA
                     YKLGLRGPAVTVQAACATSLVAVHTAVQALLSGDCDMALAGGAAVHVPARNSPYAEGGI
                     LSADGFCRTFDAAAGGTVGGDGVGVVVLKRLADALSDGDHVHAVLRGTAVNNDGSGRIG
                     FTAPSVDGQAAVVRDALSVAGVDPATVTYVEAHGTATPLGDPIEVAALTKAFRDGTDRS
                     GFCRIGSVKTNIGHTDAAAGAAGLIKTVLALEHATIPPSLHYGEPNPRIDFAATPFRVA
                     DRLEEWRPPAGTPRRAGVSSFGIGGTNAHVVLEEAPAAAPAEPAAPWQLLVLSARTPTA
                     LEAVTENLAAHLDAHPEVPVADVAWTLQAGRRRHGHRRYAVVAGTPDAVRALSGTDGRL
                     AGSDGPPVPRPVTFLFPGTGAPGEAGRLHTEHRAFRRAFDACRTAARDIEGVDVRDLRP
                     GVRPADPVAAELLAFAEEYALARTLTAWGVRPASVLGTGVGVFTAAAVAGVFSVRDAIR
                     LVAERTRLLGAAGAEPAADGVAAADGVAAADGVARFEELVREAGPRVPGIPLVRATAPG
                     DWSAYLRGEDEWHRALDLVLEDSRSVLVETGAGSALDAARRRPGHTDDHLLVAPLAGEA
                     EADGPPALLTALGDLWLAGTEVSWAEVHAARRLRVPLPTYPFERRRHLVAAAEPERVSA
                     GAEEAVAPDGASGSGNGNGNGPEGGSDGASTADRVARLFAQTLGLADVAPENSFFDLGG
                     DSLIAVQLLSRAREDFGVEIDVLALYDAETVTEFAALVDTLAGGHDSPPHTPS"
     aSDomain        23781..25040
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_esmB4_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="9.30E-155"
                     /label="esmB4_PKS_KS.1"
                     /locus_tag="esmB4"
                     /protein_end="435"
                     /protein_start="15"
                     /score="507.5"
                     /tool="antismash"
                     /translation="IAVIGMAARFPGAEDIGQFWRNLTDGLDTVTRSDPRPVPGGGPTR
                     SYVPARGLLREPEWFDADYFGYSPREARIIDPQHRVLLECAVQALEHAGHDPARYPGAI
                     GVYGGGTATRYAELARSGADSVSGATDMEILLGNANDYLVTRIAYKLGLRGPAVTVQAA
                     CATSLVAVHTAVQALLSGDCDMALAGGAAVHVPARNSPYAEGGILSADGFCRTFDAAAG
                     GTVGGDGVGVVVLKRLADALSDGDHVHAVLRGTAVNNDGSGRIGFTAPSVDGQAAVVRD
                     ALSVAGVDPATVTYVEAHGTATPLGDPIEVAALTKAFRDGTDRSGFCRIGSVKTNIGHT
                     DAAAGAAGLIKTVLALEHATIPPSLHYGEPNPRIDFAATPFRVADRLEEWRPPAGTPRR
                     AGVSSFGIGGTNAHVVLEEAP"
     aSModule        23781..26468
                     /domains="nrpspksdomains_esmB4_PKS_KS.1"
                     /domains="nrpspksdomains_esmB4_PCP.1"
                     /incomplete
                     /locus_tags="esmB4"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       24243..24290
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_esmB4_0001"
                     /evalue="1.30E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="esmB4"
                     /protein_end="185"
                     /protein_start="169"
                     /score="14.4"
                     /tool="antismash"
                     /translation="GPAVTVQAACATSLVA"
     CDS_motif       24663..24710
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_esmB4_0002"
                     /evalue="3.70E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="esmB4"
                     /protein_end="325"
                     /protein_start="309"
                     /score="12.7"
                     /tool="antismash"
                     /translation="YVEAHGTATPLGDPIE"
     CDS_motif       24771..24815
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_esmB4_0003"
                     /evalue="3.70E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="esmB4"
                     /protein_end="360"
                     /protein_start="345"
                     /score="12.8"
                     /tool="antismash"
                     /translation="GSVKTNIGHTDAAAG"
     CDS_motif       25548..25667
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_esmB4_0004"
                     /evalue="6.80E-12"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="esmB4"
                     /protein_end="644"
                     /protein_start="604"
                     /score="37.4"
                     /tool="antismash"
                     /translation="GVRPASVLGTGVGVFTAAAVAGVFSVRDAIRLVAERTRLL"
     CDS_motif       25890..25928
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_esmB4_0005"
                     /evalue="8.30E+01"
                     /label="PKSI-KS_m3"
                     /locus_tag="esmB4"
                     /protein_end="731"
                     /protein_start="718"
                     /score="-2.8"
                     /tool="antismash"
                     /translation="SVLVETGAGSALD"
     aSDomain        26271..26468
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_esmB4_PCP.1"
                     /evalue="2.90E-18"
                     /label="esmB4_PCP.1"
                     /locus_tag="esmB4"
                     /protein_end="911"
                     /protein_start="845"
                     /score="57.7"
                     /tool="antismash"
                     /translation="RVARLFAQTLGLADVAPENSFFDLGGDSLIAVQLLSRAREDFGVE
                     IDVLALYDAETVTEFAALVDT"
     gene            26523..27314
                     /gene="esmB5"
     CDS             26523..27314
                     /NRPS_PKS="Domain: Thioesterase (31-250). E-value: 4.2e-43.
                     Score: 140.2. Matches aSDomain:
                     nrpspksdomains_esmB5_Thioesterase.1"
                     /codon_start=1
                     /gene="esmB5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 200.2; E-value: 4.7e-61)"
                     /gene_kind="biosynthetic-additional"
                     /note="thioesterase"
                     /product="EsmB5"
                     /protein_id="AFB35636.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7.4e-12, bitscore:
                     37.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGKQSVAGASRTASGKPWLVGRERGPAATATLYCFTPAGGAPGE
                     YVRWSDDLPDVQVWAVQLPGRASRRAEPPYRRMEPLVDALVEQVVFEPPFAFFGHSLGG
                     LVAFEVARALRDRGREQPERLFLSSAVPPPVVLTGPPLHTLSDADLLSAVERRWGPLPG
                     PVRENPALLEILLAYYRADLELFETYDHRPGEPLDRPITAFAGTEERDTLDIEGWQAYT
                     SAPFDPHHLPGGHFYLRAERRELLRRVAASMPGPRAPRGQQ"
     aSDomain        26616..27272
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_esmB5_Thioesterase.1"
                     /evalue="4.20E-43"
                     /label="esmB5_Thioesterase.1"
                     /locus_tag="esmB5"
                     /protein_end="250"
                     /protein_start="31"
                     /score="140.2"
                     /tool="antismash"
                     /translation="TLYCFTPAGGAPGEYVRWSDDLPDVQVWAVQLPGRASRRAEPPYR
                     RMEPLVDALVEQVVFEPPFAFFGHSLGGLVAFEVARALRDRGREQPERLFLSSAVPPPV
                     VLTGPPLHTLSDADLLSAVERRWGPLPGPVRENPALLEILLAYYRADLELFETYDHRPG
                     EPLDRPITAFAGTEERDTLDIEGWQAYTSAPFDPHHLPGGHFYLRAERRELLRRVA"
     CDS_motif       26802..26864
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_esmB5_0001"
                     /evalue="6.20E-09"
                     /label="NRPS-te1"
                     /locus_tag="esmB5"
                     /protein_end="114"
                     /protein_start="93"
                     /score="28.3"
                     /tool="antismash"
                     /translation="PFAFFGHSLGGLVAFEVARAL"
     gene            27311..28384
                     /gene="esmC"
     CDS             27311..28384
                     /codon_start=1
                     /gene="esmC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     339.9; E-value: 2e-103)"
                     /gene_kind="biosynthetic-additional"
                     /note="6-acetyl-PCA reductase"
                     /product="EsmC"
                     /protein_id="AFB35637.1"
                     /transl_table=11
                     /translation="MTGVAMRYTTFGRGTGLRVSEYGLGTVNFGTGWGGGAEPDEARKV
                     FDRFAEAGGTLIDTADCYQFGQAEELLGDFLAADRDHFVVATKFGYGSAPQPRISGTGN
                     SRKNIVRSVEASLKRLSTDYVDLYWAHFPDTVTPTEEILAALDDLVRAGKILHVGLSNF
                     PAWQVSRAVTVAEYRHQAPVVAVQTEYSLADRTAERELLPMAESLGLGVGLWSPLGGGL
                     LTGKYRSGAEGRLTDWKGRVIRTENDDRRTAVLDTVIAVAEESGTPASQVSVAWVRERA
                     RRARTAFVPVIGPRSVAQLDDYLAALDVELTDGQLARLDEASAVPLGSPHEVSAAALGR
                     VLGGDAGRVRGGDVPVA"
     gene            28479..28916
                     /gene="esmH2"
     CDS             28479..28916
                     /codon_start=1
                     /gene="esmH2"
                     /note="hypothetical"
                     /product="EsmH2"
                     /protein_id="AFB35638.1"
                     /transl_table=11
                     /translation="MTASELIGVWRLASFHDVDEEGRTQEGPLGPEPDGLLFYSAEGHV
                     SVHMMRTGPQAGPRASRGGSGERPPQDYMSYSGTWRRAGDQVVHTITVAPERGWIGTDQ
                     VRDLSLAGDTLTLHGDSLIGRRQRRVLVWRRVSGEAGPGRP"
     gene            complement(28885..29847)
                     /gene="esmT6"
     CDS             complement(28885..29847)
                     /codon_start=1
                     /gene="esmT6"
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 242.2; E-value: 1.1e-73)"
                     /gene_kind="regulatory"
                     /note="transcriptional regulator"
                     /product="EsmT6"
                     /protein_id="AFB35639.1"
                     /transl_table=11
                     /translation="MEYFVAVVEEASFTKAAARLHVAQPGVSAQIRRLERKLGQELLDR
                     SGRLVRPTEVGAAVLPYARAALTAITDTRLVVDELTGLLRGHVAIGMVPACGGFDLPAL
                     LAEFHQDHPSVEITLSEGNSETMIESLRDGRLDAAFVALPGSAGPGPTGLATHVVADER
                     LVATVSPGDPLATRKEITLDDIRDRTLISLPPGTGMRTSLDAVCAKAGITPRIGFEAGN
                     PSTLAELAGWGLGVALLPESLARSHPARLCAIPFAHPELRGQVALGWRLEGPVSPATRA
                     FISRVRAATAEPGSAPADPRPRSAHGHGTVTDAPAPPPR"
ORIGIN
        1 agatctcggc cgaaaagagt tgatccggtg gatctcggtt ccggttcatc tcccgttcac
       61 cggacacaac cctcggtcgt tgccgtgtgt ctcacaggcg aaggtcaccc gcgcgcggct
      121 cctgtgccgc gtgcttctgg taggaggact cgtgggcatc cgtcgactgg ccgtatcgac
      181 cgcggtggtc gccgctctga ccggcacttt cggtgtgccg ctcgccgcgg gcaccgcatc
      241 cgccgcgggc ggtgccacca ccgtgcgcga ggacttcaac ggcgacggct accaggacgt
      301 cgccgtgagc gcgccggccg ccacggtggg cggtcacgcc tgggcgggct acctcacggt
      361 cacctacggt tcggcgaacg gcctcgacac cgctcgtacc accgtcgtca cccaggacac
      421 cgcgggcgtc ccgggcgccg cgggcgacaa cgcggtgttc ggctacgcga tggtcccccg
      481 cgacctggac ggcgacggcc tcaccgacct ggccgtgacg acccgcgagt accgccccga
      541 ggagaacgtc agcggatcgg tgatcgtcct gtggggccgc acgacgggca tatccggcca
      601 ggacgccgtc cgcgtcggcg cacccgcgaa cgccgaggtc ggcaccggca tcaccgcggg
      661 tgacttcgac ggggacggac acgtcgacct gttcatgggc aacggcgacg actacgacta
      721 ccgcagcgtg ctctacggcc cgttcgaccg cagcggcacc cctgcgcgcg agcaggacct
      781 gatggtgttc agcaccgaca acacgctctc ctccaccgcg gccggcgact tcgacggcga
      841 cggcatcgag gacctcgcga cgttctacgt ctacgagaac cacgccgagg gcggcaaact
      901 gtggctcggc acggaggacg gcctgtccac cgtcccgcag cggctgccct ccgcgtccgc
      961 caccgccgtc gccgacttcg acagggacgg ttacgccgac ctcgccacgc gtgtcttccc
     1021 gggcggcgac accgagatgg tggacgaccc ggggaccgtc aagatctact acggttcgcc
     1081 ggccggtccc agccagaccc gtacgcggac cttcacgcag gagagcgcgg gcgtgcccgg
     1141 cgcgagtgag aagaacgacc acttcggcgc gcgcctgagc gccggcgacg cgaacggcga
     1201 cggatacccc gacctggccg tgggcgtccc cggggaggcg atcggctcgg tggccaaggc
     1261 cggtgccacg gtgctcctca agggcggcgg cgccggactc accggcacgg gggcgcaggc
     1321 gttccaccag gacaccccgg acgtcccggg ggtcgccgag aagaacgacg tgttcggcgc
     1381 ctcgctgcgg ctgctcgacg tgaccgggga cggaaaggcg gacctgaccg tgagcgcccc
     1441 gggcgaggac ctcggcacgg tgcggaacgg cggcgcggtg tggctgctgc gcggcgcggc
     1501 ggccggcctg acggcgtcga agtcggccgc gcacaacccc gtggacctcg gaacgccggt
     1561 ggcgaacgcc cagtacggct gggacctcgg cggcgacaac ggcccgggcg tggcgatccc
     1621 ctagccatcc ggacggcgcc gggggcagct tctgctcccg ggccgggcgg aggattattg
     1681 cagagcctgc atttttgcgt actatgcaat acgtgagtgg gaagagggcc gcggaagacg
     1741 gctggcgcga gcgcaagaag cgggccaccc gcgccgcact cgtcgagtcg gcggtacggc
     1801 tggccgccga gcgcgggctg gagagcgtca ccgtcgacgc gatcagcgcc gcggcggggg
     1861 tctccgcgcg caccttcttc aactacttcg actcccgcga cgacgtgttc gtcctgatcg
     1921 gcgcggaatc gagcgcccgg gtgcggcgtg ccgtactgga cgccccccgc gcgctgtcgc
     1981 cgcttgaggc gctgcgcgac gccatggcgg aggagttgca ggaggtcgag cagcagacag
     2041 agctgtggcg cctgtacgcc gaggtactgg acaggactcc ggctctgctc gcccgtagtc
     2101 tcggtgccta catggccgac gagatcggtc tggccgaagc cgtcgccgag cggatcggcg
     2161 gtccctcgtc cccgctcacc ggcaccggca ccgacaccgg caccgggccg gacggcccgt
     2221 cggaggacga gcggcgacgt gcgctcgacc tctacccgcg gctgctggcg gcggtcggtg
     2281 ccaccgccgg gcgggtcgcc gtggagcact ggtgcgtccg ccaggacggg gcccgcttcg
     2341 ccgacgtgtt ccgcgaggtc ttcgagcaac tggccgcggg actcccgcaa ccgccggagc
     2401 cgaccactcc cggtcgacgc tgaccggact ccttgcctcg gggcacccca ccgctctcct
     2461 tccgtgagtt ctgcaggttc cgcaggttct gcgggttctg cggtttccgc gggcgcgggg
     2521 tgccccgttc cgaactgtga aagagatgaa gtgacttcac cagcggcgcc tgaagaggcg
     2581 tccccgaccg ccatgtccca ccggcagatc atgcaggcca tgtccgggct gatggccggc
     2641 atgttcgtcg ccatcctcgc cgggaccgtg gtggccaacg cgctgccgag gatcatcgcc
     2701 gacctggggg cgagccagtc ctcctacacc tgggtcgtca ccgccgaact gctggccatg
     2761 acggcgaccg tgccgttgtg gggcaagctc gccgacctct acgaccagaa gctgctgctc
     2821 cagctgtccc tctgcatgtt cgtggtcggc tccctgctcg cgggcttctc gcacgacgtg
     2881 ggactgctga tcttcagccg ggtcgcccag ggcatcggcg cgggcggcct caccgcgctg
     2941 gcgcaggtcg tgatggcggc cgtcatcccg ccccgtcgac tcgggaagta cgcggggata
     3001 ttcggcgcgg tcttcgccgt gggcaccgtg gcgggaccgc tcatcggcgg cgtcctggtc
     3061 gacacctcct ggctggggtg gcgctggtgc ttcttcatcg gcgtaccgtt cgcgctgctg
     3121 gccatcgtgc tgctgcagcg caccctgaaa ctgccgaccg tccgccgcga ggcgcagatc
     3181 gacttcctgg gcgccttcct gatcgtcgcg ggcgtctgcg cgctgctcat ctgggtctcg
     3241 ctggccggca acgagttcga ctgggccccc tggcagaccg cggccctgac cgggggaggc
     3301 ctcctggccc tggtcgccgc actctacgtc gagtcgcgcg tcgcggagcc gatcatcccg
     3361 ctggggatct tccgcaaccg caccgtgtcg ctgaccacgc tgtccagcct gttcgtcggt
     3421 gtggccatgt tcggcggcac cgtgttcctc tcgcagtact tccaggtctc cctcggcaag
     3481 tcaccgacgg tcgcgggcct gatgagcctg cccatgatcc tgggcctgct ggtgtcctcg
     3541 accgtcgcgg ggcagatcat cagtgccacg ggccgctgga agatctacct ggtcctcgcc
     3601 gcccagaacg acgtccccgc cgccgaactc ggcgccgcca cctcggtgct gtccttcttc
     3661 cgcagcatgg gcggcaccat cgggaccagc gtgctcggcg cgatcctcgc caaccgcgtc
     3721 gccagtgaga tgaccaaggg cctgcaggac gcaggggccc cggccggctc caccgagggc
     3781 ggtgcccaca gcgttccgga catgacgaag ctgccggccc cgatgcggga gatcgtggag
     3841 cacgcctacg gagtcgccac gggtgacctc ttcctcgtcg ccaccccgtt cgccctcctg
     3901 gcgctggtcg cggtgctgtt catcaaggag aagccgctca aggacaccag cggcatggag
     3961 cgcctcgccg aggagaagga gccgtcggca gcacggtgac cgcgaagggc cgacgtgacg
     4021 gggccggagg attcgacggt ggtcaggacc ggcgtcgtca cgtcggggcg tatagaaaaa
     4081 tgatggtccg tgcggccccg gatatagcag gcgtcgccag gatgacgtgg acgacgttcc
     4141 gtgatggcta cctatggggg catcatccat gtctgacgcc aagcagcagg ggttcgacga
     4201 ccacgcagaa ctgcggcgga tcaaccggga gacggttgag aagtacatgc acaccacggg
     4261 gcaggaccgg ctcgaacggc acctgctctt caccgaggac ggatccggtg ggctgtggac
     4321 caccgacacc ggcgagccga tcgtcatccg cggccgggac aggctcggcg agcacgccgt
     4381 gtggtcgctg aagtgctttc ccgactgggt ctggtacaac atcgaggtct tcgagaccca
     4441 ggatccgaac cgcttctggg tcgagtgcga cggcaagggg aagatcctct tccccggata
     4501 tcccgagggg tattaccgga accacttcct gcactcgttc ctgctggaga acgggaaggt
     4561 cgtgcagaac cgcgagttca tgaacccgtt cgagcagttg cgggccctgg gcatcccggt
     4621 gccggagatc aagcgggagg gaatccccac ctgacgtggt gaacagccgg gcacaggacc
     4681 gaagagaaga ggtgcgggcg ccgtgagggc catgatcgcc tggtgggcac tcgacgactc
     4741 cgaccagacc atcgactcgc tgcgggactt cctgcgggac gaggccgtgg acgcgtgggc
     4801 cctggtacgg gggatgccgc tcaagttctg gatcgccgac cgggagaaca accgctgggg
     4861 agcggtcatg ctctgggagt cggcggaggc cgccgccccg ccgctgccga gaagtcccgc
     4921 cgaactcatc ggatacccgc ccacgcaccg gacctggttc gacatcgagg ccgtgatcga
     4981 gggcatccac tccctgccgc ccctggccgg gctgggactg gccctggaca cgtgaacggc
     5041 cggacaccgg acatacggag aaaccccatg agcgtgaccc cgcagaagat cgttccgaag
     5101 tccgccgacg cgctgtcgga gtccggaacg ccccccgacg acccgatcga gctgttccgc
     5161 gcctggctgg ccgacgcggc ggagaacggc gtgcgcgagc ccggcgcgct ggccctggcc
     5221 acggccgacg cgcaggggcg tgcgtcgaac cggatcatcc agctgggccc gctgacctcc
     5281 gacggtttcg tgttcgccac gcacgacatc agtcccaagg cccgcgacat ggaggcgacg
     5341 gcctgggcct cggccgtcct gtactggcgg gagaccgacc agcagaccgt cctgagcggc
     5401 cgcgtcacgc ggctccccga cgtggagtcc gacgagctgt ggagggtgcg gtcgatcgac
     5461 gcgcaggcga tgacgaccgt ctcgcggcag agtgaaccgc tcgacgacgc ggcggccctg
     5521 cgcgccgagg tcgggaaact cgccgaggcc gggaagccgc tgccccggcc cgcgaggttc
     5581 gtcgggtacc acctggcgcc ggagtccgtc gagttctggc acaccggcaa ggaccggctg
     5641 cacaagcggc tgctctactc ccgggtcgcc gggggctgga gcgtcacccg cctgcagccc
     5701 tgagccccgg gacagctccc ggacggatag gcccgatcgg ccgccccggg ccgggacccg
     5761 cgcgggcccc gggaccggcg ggtcagccgc ggatcacggt cttcgtacgc atgaggaagt
     5821 cggagagata gccgtcgtgg ggcatcccga tgtcggtcca gtgcgtgggg tgccggccga
     5881 cgtagaggtt gccgatcgtc ggctcgttca ccagggtgtc gatgaggtgc tcgtcctcgg
     5941 tgaccacggt gagcaccagg gtgtccctca gcgcttccag acctgcttcg ggcgtccacg
     6001 gcgccaccca gacgcagggg aagggcagtt cgaggtcggc ctgcggcgcg gtcgggctgt
     6061 cgagctggtg gacggtgggc cgtacgaccg cgctgccgtc gccgagctcg tcgacgaagc
     6121 cgtcgccgcc cagccaggcg cgggtttcgg cggcattgga cagcacgtac cgttcgaggg
     6181 cgcgggcggg catccgggcc tggaccggga ggaccgcctt ctcgtcctcg ggaggcaggc
     6241 tgggaagggc ggcgagccgt gcggcgagag cctcggccac cggcgccggg tcgccctcga
     6301 ccagtaccgc ggtggcgttc acgcagccgg tgccgccgtg gtgggcgacc gagtcgacga
     6361 tcatgtccag atggtcgcgc cagtcggcgc cggcggtcag caggaccttg gaacggcccg
     6421 gctcctggga cagcacggtg ctctccccgg cgtacttgcg gatcacgtcg tcgccgccgt
     6481 acgcgaggtc ggcaccgcgc aacagggcct cacccggctc ctgttcggtc gggagcagga
     6541 cgacgtggtc ggtcccgaac cccgcggccc acagcgccgt gacgagccgg tgcgcggtgt
     6601 agggctcccg gcgggtgggc cgtaccgcca cccggtagcc cagcgcgagc gcctccagcc
     6661 agaggctgtg cgccccgggg tgcaccccgg agacatggac cgcgagcacc tcgccgcgcc
     6721 gggtccacac ggcccggccg gtacgggtga gcgggtcgcg ccagtcgccg gccgacccct
     6781 ggggccgggc gtactgcacg ctgtcgtaca cgtgcgcggc gcggtgcgcg gcggtccggg
     6841 tggcctcccg gaccaccggg acgggcagtc cggagacccg gctgacccgg tgttcgtagg
     6901 cgctcaccga gaggccgccc agggtggcgg tggcgaacag ctcgccggcc cgggcgatcg
     6961 cggcgatcct ctcgtccacc ggcagcgggg tggccctgcg cagggcggac atggcacggg
     7021 tgacgaacag ggtcggcacc aggcccagcc gggcggccgg gttgccggcc acgtccttga
     7081 tctcctggtg gctgcgggag gcgtaggggc cgttgggacc cagcgcgtcc agcgtgacga
     7141 cgtcggccgg agccggggcc ttgtcctggt tctggttctg gttctggggc ggtgactgtg
     7201 tcatcagtag accccctcga tgacggcctc gtcctcgaaa tgcgtgaccg gggcgatgtc
     7261 ggcgaccgcg tccccgatct gtcccggcag cggagcgatc cgcgtggcga ggtcgcgctc
     7321 caggttgttg ggcaggaaca gcgacttgct gacgtggttc atcaccaccc ggccgcgctc
     7381 gccgtaggga acggtcttcc tggtctcggg gttgacgacc gagaacgtga tgtagggcga
     7441 gaaggtgtcg aagacacagg ggtcgtcgtc gccgaggccc gggcgctgcc cggcgatccc
     7501 caggatcatg gtgctgccgt agtggccgta gagcgtggtg tcgggaaaca cctcggtgcg
     7561 gtagaggtag cgcgagtccg cgtccatctg cgtcccgccc caccggatcg cccgtacctt
     7621 ccggttgacc aggtcgacga gttcgtcacg gcgggtcagc cgctccagga gcgggggcgt
     7681 gatggccatg accccgatgt cctgcgtgcg caggacgaac gcggcctggt cgacgacgtg
     7741 ttcggcgtag gcgtccgcct ggtcggtctt cccctcggcg atgagccgct tcacccaccg
     7801 cgggtcgagg tcgaccggga agctcagcga accgtgggcg gccgcggagc gggagaacag
     7861 ctcgccgacg acgtggggcc cggtgggggt gacgccgagc cagttcgcac cgcgcggaaa
     7921 gccgtgcgcg tccaggttgg cgacgctcca ggcgaccacg cggtccatcc agtcggccag
     7981 gcacacgacc cgtttcggcg cgccggtggt gccgccgctc tcgtagacgc cgacgacgtc
     8041 gggggcgtcg tagccccggg gcacgagatc ctgggcgggg acgtcccgca gttcgttgac
     8101 gacgttgggg aagagctgga ggtcctggtg gctcgtgacg tcggcccgcg ggtcgaagtc
     8161 gagcttcttg gcgcgctcca gccagtaggg ggacccggtc tccgggctga aatgccagtc
     8221 catcgcggcc tggatgaact cgtccggatc gggccggacg tcgaagggca ggtccaggac
     8281 cggattggcc tctcgcgaca cgatgactcc ttgtcagctg atgcggattt ctgcggccga
     8341 ctgcggattg agggccgtct gccgggcccg ctcctccagc gcgcccgcga tgtcgctcca
     8401 ggaggcggcg tactgccggg cgacctcgga gagcatgccg agggtgtgtt cgggaaggtc
     8461 cttgatcagc tgttcgcggc ggtcggcgaa caggatgtgg ggatccatga ggcgcagcag
     8521 gacccggccg gcctccgtga accgcagtga ggggtccttg cgcaggacgt tcagggcgtg
     8581 ccggccgtcg gccggcaccc ggtggacggc cgcggggcgc ccgaagcgcc gggcgccgtc
     8641 cttctcggtc ctcgccggcg cggcggcgct tcctcccgcc tcctccgcgg ccgggaggaa
     8701 gcgctgccgc acgggtatgg ggtcctcgcc gcggctgagt ttgtcccgta cgtcccggac
     8761 ggtctccggc gatatgccgg ccaccctgga gacctcccgc agcgagccgc ccgggttggc
     8821 gctgaggtac tcggcggcca gtcggcgtcc gcgctcggtg ttcagcggcc tggtgcgccc
     8881 gtcccggccg accctggcga gcggctggtg cgccccctcg gcggtgcgtt tgcggatctc
     8941 gcccaccgtc ttgccggaca gtcccgtgag cgaggcgatc gcccggtccg acaactgcgc
     9001 gtgggacacg acgatccgcg cggcggctct tcggcgctcc gcgagggtga gcggcagccc
     9061 gtgcttgacg ttcagccgga cggcgagcac gaaggcgtcc tgttcggtgc cgtcgaagta
     9121 ccgcacccgg atcgtctgct ggccgcgcag gatcgcggac cgcacccggt gcataccgtc
     9181 gatgacccgc atgctcggcc ggtggacgat gatgggcgga agcgtcccct ccgtctcggc
     9241 gagcgcctgc acatgactgg tgatctcgcc gccgatccgc ggggagtacc ccgggatcag
     9301 caggttcacc ggcgcggtct cggtctcttc ggaagacggc tcgacagtgc tttccggatt
     9361 ctcgggtaag gattttgagg tgccggtcct acggatcacc gaaatccctc ctaggccttt
     9421 cctgtgcgct ggtggtctca cgttcaagca tgagattcgg gactatattt aggcgggcgg
     9481 gggctatatt ttttctatac ggcgccgacg gccccggcag gagccccggt gcgcgtcggg
     9541 tgtcgtcccg aatggcctgg accagcgtca agtcggcgcc aaagcaaggg agtcgaacgg
     9601 ccgacgtccg ttcgacgccg cgggaagcgt ggctttcggt gtggtggggg tcactggtag
     9661 cttcgccgat atgcatagct acgtagtcgc ggatgccttt acggacacgc cgcttgaagg
     9721 aaatccggtc gctgttttct tcgacgccca cgacattcct gacgcgcgta tgcagaaaat
     9781 agcgagggag atgaacctct ccgaggtcac ctttgtgctc cccgccgaga agggcggcga
     9841 cgcgcgcatc cgcatcttca caccggtcaa cgaactgccg ttcgcgggac acccgatgct
     9901 gggcaccgcc gccgtcctgg gcgacacgtt cgagggcgac cggctgctcc tggagaccgc
     9961 catgggcgtg atccccttcg acctcgaccg cgagaacggc agggtcacct ccgtccgcat
    10021 gcagcagccg gtccccgtct gggaaccgta cgagcacgcc gacgaactcc tggagggcct
    10081 cggcctcaag tcgtccacgc tgccggtgga ggcgtaccgg aacgggccgc ggcacgtctt
    10141 cgtggggctg gaggacgtgg cggcgctgtc cgccgtccgg cccgacctcc gtgtgctcgc
    10201 gcgctttccc gacatggccg ccaactgctt cgccccggcg gacgggcact ggcggagcag
    10261 gatgttctca cccgcctacg gggtggccga ggacgccgcg accggatcgg ccgcgggacc
    10321 gctggcgatc cacgtcgccc ggcacggcct gggccggttc ggccagcggg tcgagatcct
    10381 ccagggcgtc gagatgggcc ggccgtcgac gatgatcgcc agggccgagg gcaccgcgga
    10441 ccggatcacc tccgtcgagg tgggcggggc cgccgtcgtc gtcgccgagg ggaccctgcg
    10501 gatatgacgc gcactagagc cgccgcgccg gaccggaacc cgggcgggac gggcagcgcc
    10561 gagtgatgtc ggacgacacg gtcaccgagt ggcccatggc cggccgcaac accgaactgg
    10621 acaggatcga ggcggcggtg gcccgcggcc acggcgccct gctgaccggg gtccccgggg
    10681 tcggcaagag ccggctgctg cgtgcctcgc tgcgccgggc ggcggcgcag ggggccgagg
    10741 tcaggctggt gagcggggcg gggatgtgcg gggcggaggt gtcgtcgctg ttcaccggct
    10801 gggggagcgc atccggccgc gaacagcccg acgcctcccg gcacctcctc gacgagacgt
    10861 tccccagccg ccgcacgccc tccgcggacg gtctccaggg gcagttcgtc ctcggcctcg
    10921 acgacgcgca ctgtctggct ccgggcttcg cggcacgcct gcgggcgggc gtcgccgagg
    10981 gacggctgac cctggtggcc gccgtccggg ccggcgtccc ggcgcccgac gggatccaca
    11041 ggctctgggt ggaacggctg gtcgagcggg tggagatcgg ggaactcgac agatcggcgg
    11101 cggccgacgt cgtccacgcg aggctcggcg gacacgtctc cgcggcggcg caggagcggc
    11161 tgtggcagct cacgcacggg aacgcgctgc tgctgacgga actcgccgac tccgccctcg
    11221 ccgacggcag cctgcgccgg gaggacggca cctggctgtg ggacgggctc aacggcagac
    11281 cggccgggcg cctcacggac atggtgcacc tgcgcctcgg ccacctctcg ccggacgagc
    11341 gccggctcgt gcagatgatc gccctcgccg agccgctgga ggcggagctg tcggccgtcg
    11401 ccgagctggc ccacgccgtg gaggcgctcg acagccgggg cctcatcacc gccgaactca
    11461 gcggcctgcg actgcgcttg agactggcct accccctcta ccggcccgtc ctcgtctcca
    11521 gcctgcccga actgaccggc ctgcggctgc ggcgccggct cgccgacgcc ctggaggaca
    11581 ccgggctgcg ccgcgacgac gacgtcctgc gcatggtcgt cctgcggatc gatgccgggc
    11641 agctgccgtg cgccgagcag ttgcagtgtg ccgcccggac cgcgctgcgc cggctgcgct
    11701 tcgcgctcgc cgaacggctg tgcctgctcg cgctcgcggc gtccgacgcc gacgtccccg
    11761 ggctcacgct gctgcgcggc cgggcgctgg agggccaggg acgccaggcc gaggccgaga
    11821 cgctgttcgc cgcggtgtcc gccgcggacg ccccgaccgc ccccgccgtg tgggccgagg
    11881 ccgtgcaggc ccgttcggag aacctggcct gggggctgca cctcgtccag gacgccgtga
    11941 ccgtcctgga cgaggccgtc gccaccgccc cggaggcgga cctggggccg ctgcagggca
    12001 cccgcaccgt catgatgctg ctgggcgacc ggctggagga ggccgcggcc atgggcgaga
    12061 cggtgctcgc cgaaccgcgc gatccggccg tggtccagcg ggtcctgccg cccgccgcct
    12121 tcgcccacaa cgaactgggc gacgcggtcg gtgcgctctc cctcctccag cgctgccgcc
    12181 ccgaaccgga gacctggagc gacgaggccc gtctggccca ccagctggtg gcggcctgcg
    12241 ccgcgctgca gaccggcgcg gtggcggtgg cggccgcggt cctggacggc ctgcccgccc
    12301 aggacgcgga cgacgaccgc accggcgagc tgtggaccgc gtcggtacgg gcccggctgt
    12361 accgcagttc gggccggttc accgagggga tcgccctgct gcggcgggtc agcgcgatgc
    12421 cggacacccg tgactggctc acgaccaggg cctggcgcct ggcccagatg gcgggggcgc
    12481 tcgccgaggt cggcgaacac gccgaggcga tgcgcatcct ggtcgaggtc cgtgccgagg
    12541 agagcggcac cgtgcggtac ccgctcgccg cggacggggt ggccatggag cgcgcgctgg
    12601 tcctcgcgca cgtcggggac ttcgccggcg cgctgcacga cgcactggaa ctcggcgagc
    12661 gcgcggccgc cgcgggccgc gccttccagg cgctcggcgc gctgcatctg gccgccagga
    12721 tcggggaggc ccgcgcggtc gccgagcggg cctccgacct cgccgagcac ctcgactccg
    12781 gcctcgccga gctccaggcc gagcacgtgc gggcgctggc cgacgcggac ggcgacgcgc
    12841 tctccgagct cgccgagcgg ttcgagctct cggggctgct gccgctggcc gccgaggcgt
    12901 cggcgcaggc gtgccgcgcc caccaggccg ccgggcggca ccgcaagagc cgggccgccc
    12961 ggtccgtctg ccaggagctg ttgcagcggt tcggcggaac actgccggtg tgggccgcgc
    13021 tggacgcgca gggccccgag cagtcggccg aactcaccgg ccgggagcgg gaggtcgcgg
    13081 cgctggccgc ctccgggctc tccaaccagg acgtcgccga ccgcctgggc gtgtcggtgc
    13141 gcacggtgga gaaccacctg caccgcgcct acggcaaact cggcgtcacc acgcgggccg
    13201 acctcgcccg gcacctggac tccagactgc ccacggacgg cttcggagcc gccccggccc
    13261 ccggccgcgg ccgcgcgccc cgagccctgg acccggctcc accgaccccc ggcacaccgg
    13321 ggcgccggcc cggcaggacc ggggcggcca ccccctgaga accacgacag ggactcgccc
    13381 cgtcacccgg ggctctggcc ccgccgcgcc cctgccgggc ccggtcctga cggcgcggac
    13441 cagggtactg acgtgacgcc acatggtggg ccgggcaacc cggtcggccg gtacggcggg
    13501 tcgcgacgac ccgcccgggg ccggcccggg cgccccgagc ggctaggcga caaagccccg
    13561 ggaggggggc cggccttccg gcccggcctc ctcaggcgtc ccgggccgcg tgcgccctcc
    13621 gcacccctgc cggacccggg cccggcgacc cggagtgccg gacgaggacg ctgaagcggc
    13681 gtcgggtcgg cggtcggcca gctgggttcg ccggaacgtc cggccggccg gccaggtccg
    13741 ccggagtgtg cggctgggcg cccggccccc ggaacggttg tccgggcggc tgacgccgcc
    13801 cgtcacggcg tgggcagcag attcgtgatc atgcggctca ggatggccgc gccgtcgcgg
    13861 gacatcaccg acgccggatg gaactgcacc gacgcgaacc cctggccccg catgccgtgc
    13921 acctcgtggt ccaccgggtc cctgcacacc tcgaccgggc ccggccgggt gggcgggccg
    13981 gggaaggagt cctgcgggct gacggcggcg aaggtgttgt agaagtacac ggcctcccgc
    14041 cgcccgaaga agtcgatctc ccgctgcacc ccctggttgg gcacctcctt gcggaccagc
    14101 tccagcccga ggaccccgct cagcgcctgg tgccccaggc agatggagag gaacgggatg
    14161 tccgtgccga gcagccgcct cgtcaccgca cgcagatgcg cgttcttggg gtggctcgtg
    14221 tcgcgcggat cgccgggccc gggccccacg acgaccaggt cgtggccctc gaaccggtac
    14281 tcctcgtcga agcggtgcac gctcacgtcg agaccgagtt cggacatcat cgccgcgccc
    14341 atcgcggtga aggtgtcctc cgcgtcgatg agcagggccc tgcgcccggc cagccgcgac
    14401 gacccgccgc gccgggccgc gggtggctgc cgccagaagt cggccatcgg gacgttccgg
    14461 gcggccagcg cgtcggccac ctctggcaga tcgcccagcc ggggcacgcc gacggcaggc
    14521 cgcgcggggt cggcgccggt gccggggtcg gcgtacaggg cggcgagcag acccgacgcc
    14581 ttggccctgg tctcctccgc ctcggcccgc gggtcggaat cgcggaccag ggtcgagccc
    14641 acaccgagcc gcagccgccc ggtgcggtcg atgtcggcgg tccggatgag gatggccgag
    14701 tccagccgcc gcagcccccc ggcgtcccgg cccagcaggg ccaccacacc ggcgtagtag
    14761 ccccggccct cgttctcgta cttcgcgatg acgcggcagg cgctctccag cggactgccc
    14821 gtgacggtgg gcgcgaacag cgtctcccgc acgacctcgc ggatgtcgcg ggtgacctct
    14881 ccctcgatga agtactcggt gtgcgcgagg tgcggcatct cgcgcagacg cggcccgacc
    14941 acgcgggcgc cgccgtcgca cacccggcac atcatcttga gttcctcgtc cacgaccatg
    15001 tagagctcgt tggcctcctt gcggtcgccc aggaactcca gcgccccctt gagcgtgggg
    15061 ccggacggcg gatagcggta ggtgccgctg atggggttca tcacggccgt gccgccgtcc
    15121 agcgtgaggt gccgctcggg gctcgcgccg atgaaggtgc ggccgcccac ccggatcagg
    15181 aacgtccagt gggcccccga ggtgtgccgc agcagccggc cgaacagggt gagcgcggtc
    15241 tgcgccgacc agttcgcgag ccgcgcggtg aaggcgcgct tgatgacgaa gttggcgccc
    15301 gcgccggtgc cgatctcgtc ggtgaggatc cgccgcacgg tggcagcgta ctcctcgtcg
    15361 tcgatgtcga agccgccgtc gcgcacctcg atgggcaggt ccgggagccg ggccagcacc
    15421 tcgtcggtcc gcgcgacggc ctgctcgccg accttcatga cgagcagcgg ttcgccgtcg
    15481 tcgttgtgct cgtagccgcg ctccgcgatc tgccggaacg gcagcagggc cagcacctcg
    15541 tgccggtcgc ggccgccctc cgggggcagc gggatgtcgg ccgtcgaccc gacctccgac
    15601 acgtctccgg ccagcaggtc gatgtggccc gcacccgacg ccctcggccg gtgcagcagg
    15661 gcgaacgagg gcggcggcgt cccgcccgtc agccggtcga gcagggagcc ggccgggtcg
    15721 cgagcggtca cagcgctgtt cccgtgacga ccctgcccag ggcgttcacc acggtgtccg
    15781 tcggcaccac cacggagcag cgggcggccg cgtactcgac ggccatccgg tggtcccgcg
    15841 cggagaagtc ggcgacggcg tcaccgacca ggaacgtctg gatgtcgtgc gcgaacgcct
    15901 cgcaggcggt ctggaggatg cccacgtggg cgtagacgcc gcacagcacc agctggtccc
    15961 ggccccgctc gcgcagcagg tcgagcagtg gcgtccggaa gaacgcgctc ggccgccact
    16021 tgtcgaggac gacgtcgtcc ggaccgggcg ccagttcgtc gggcacgccc cgctgctcgg
    16081 ggtcggcact catccccgga ccccagaagt ccttgagcag accgcgctgt tcggcggtca
    16141 tgtcaccggg ctgcgcggtg tacgccaccg ggacgccggc cgccacggcg gcctcccgga
    16201 gccggacgac atgaccgacc aggtcggtca ccggagggcg gccggccggg aagggccgga
    16261 ggaagaagtg ctgcatgtcg tgcacgagga gcacggcgcg ccgcgggtcg accgtccagt
    16321 gcgccgtgtt ctccggcagg tcggcggctt cgggcatggg gtagggcgct atctcgggga
    16381 tggacggagc tgccatgtcg gctctccttc tcgcggggcg gtcagttgga gcggggacgg
    16441 agggagtcga ggtgacgcgc ccagctgtcg atcgtggggt cggcggtcag gacctcgaac
    16501 tccacgggca ggccctcgcg gcgccagcgg ctgctcagcc gcatgacgtc cagggaaccg
    16561 agcccgagga acacgaggtt ggcgtccccc gggatgtcgt gcggggcggt gccgatcagc
    16621 gccgccacgg cggtgcgtac ctgatcggag gtggagaccg gctcgtcggc catggtggtg
    16681 cccttctgtc tgtccgtgtc ggggtgccgc gtcagctcgc gggacggtcc gggtccgtcc
    16741 ccgaggaatg ggtggtggcg aggaaggccg aggcggcggg ggtggccgcg ccgcggctgc
    16801 gggccgccag gaccttcttg tcgatcttgc cgaggccggt gagcggcagt tcgtccacga
    16861 cctccacacg atccggcaac ttgtaggcgg ccaggccgcg ttcggtcagc gcggccttga
    16921 tctccggcag cgacggaggc gcgccgacgg gcacgatgta ggcgcagatg cgctcgccga
    16981 ggtagtcgtc cggcacgggg acgaccgccg cccgcgcgat cgcgggatgg gtctccagat
    17041 gtccctcgac ctcgccggcg gacaccttct cgccgccgcg gttgatgagg tccttgatcc
    17101 ggccctcgat gacgagccgc ccctcgggcg tcagccgcgc caggtccccg ctgcggtaga
    17161 agccgtcctc ggtgaaggcg cgggcgttgt gctcggggga ccggtagtag ccgcgtggcg
    17221 tgtaggggcc ccgggtcagc agctcgccga tcgtcccggc cgggacctcc tggtccttgt
    17281 cgtcgacgat cttcatctcg tcggccgggg agatggggag gccctgggtg gtgagcaggt
    17341 cctcctcgga gtcgccctcc cgggtgaagc agatcagccc ctcggccatg ccgaagacct
    17401 gctggatccc gcagccgagc tcgggccgga tgcgttccgc gaggtcccgg tggagcttgg
    17461 aaccgccgat ctggagggcg cgtacggagg acaggtcggg cttcatccac tccgcggcgt
    17521 ccagccagag ctggacgacg ctcgggccga ccgaggtgac ggtgacgccc tcccgctcga
    17581 cgaccgggaa gcagagctcg ggcgtggcgt ccgacgcgag caccgcggta ccgccggaca
    17641 gcagggtgcc gatcacgccg gggcagccga aggtgaagtt gaactcgacc ggcagcaccg
    17701 cgaggtacac gtcgttctcg gtcagccgga tcgcctcgac cgccgcgcgc atcatgtaca
    17761 cgtagtcgtc gtgggtgcgg gggatcagct tcggcagggc ggtggtcccg ccggacagca
    17821 ggaagaacgc cacgtcggcg gggtccgggg cggggaagga cgcactgccg gacggatcgg
    17881 ccgcggcccc cgcggcctcc accgcggaga gggcgatcat gtcgtcgtcc gccgccgcgt
    17941 cgtccagggt gaacaggtgc cgcagtgtcc cggtctcgtc gcgcacccgg cggccgaggg
    18001 ccgggtggtc gaagccgcgg tgcacgccgg gcaggacgta gccgaccgca ccggagatgt
    18061 cgacgaggtg ccggatctcg ctcgcccggt gcgacgggag cgcgaacacg ggcttggccc
    18121 cgagccggaa cagggcgaag cagaccacca cgaactccgc cacgttgggc agctggacca
    18181 ccacccggtc gtccgcggcg atccccagct cccggaaccc ggccgcggcc caccgcgacc
    18241 gccggaccag ctcgtcgtag gagacccggc ggtcaccctg gaccagcgcg gtgcgggagc
    18301 cgtgccgcgc ggccgaggac tccagtacgt cgatcagggt ctcgccgctc cagtggccct
    18361 gcgcacggta ccgctcggca tactcatccg gccagggcgt gcatccgtcg agcatcggtc
    18421 gtctccttcg gtcgctcatg ggcatctcgt gacagggggc ggcgcgggga acggggcggg
    18481 cgcagacggt ccggcgcgcc ccggaccgcg ggggcgctca cgcgtcctcc ggtccccggg
    18541 tgatctccac gaccgcgcag ccgacctcca tgccgggggt ggtgccgatc atcagtaccc
    18601 ggtcgcccgg gttcacctgg cgggtgagcc acaggtgttc gagcccgatg acgacgtcgg
    18661 acatgctggc gtgaccgatc cgccggctgt gctcccaggt cccgcggtcg gcgtcgatgc
    18721 cgagcggctc cagatacagg gcgtgcaggg agccgtggtg gaagccgacg tgcgtgaccc
    18781 gcgcgacctg atccatcgtc aggccgacct cggccaaggt gcgttgtgcg acgtcggcga
    18841 gcaggtcgat gaagttgcct cctggcggcg gggcgccctc ggcccacttg cgctgccaga
    18901 acttcacccg ggtctcgaag tcgaggagct tgtgcgacgg ttcgcgcggc ggcatcagcg
    18961 acccctcggc gcggtgccgc cactccagct tcgggtccga gaccgagccg accgcgagca
    19021 ccttggcgaa gccgccgcgc cgcgacacca cgatggccga gccgctgtcc gccatgaaga
    19081 acagtccgga ggcgcgccag cggtccacca gcggggtgtt gaagttgtcc gcgcccgtca
    19141 ccagggccgc gtccttgtcg ggggacgcca tgagccggtg ggcggccatc tcgatcccgg
    19201 tcatcaggcc gttgcagccc tgctggatca ccgcggcgct gatcggccgg tccagcgtgt
    19261 tcagcaggat gtagtgcgag ggggaccagc cgtcgtgcgg gccctgcagg aacgtggtgc
    19321 tgtgcagcag cgaggcgaag tcgtcggggt ggtgccccga ccgccgtatc gcgatctcgg
    19381 cggcccggat cgccatgtcg ggtgcgccga gggtgtcctc gaccgccacc gattccatgc
    19441 cggaggcccg gtgttcctcc tcggtgtaga gaccggcctt caccgcctgc tcgacgggca
    19501 tcagttcggg gatgtaggtg cccaccccgg cgaggtagat gttctcaagt ttcatcgcgg
    19561 tactgcctct ccctgcgcat gtcgtcctcc gcggacgagc cgggcccagc agagcacggc
    19621 ggccgcggtg gcttcctgag taggcgctac tcagcgcccc ggcgccggcg ccgcggccag
    19681 cgcctccagc acgatgtcgg cgacgccctc gggggtgcgg ccgccggtgg cgaccaccac
    19741 gcgggcgacc tgcgtgtaga ggggccggcg cgacgcgctc gtcgcgcgcc agaccgcctc
    19801 gggatcgacc gccagcaggg gccgtacggg gccggcggcg agccgccgga cggcgtcctg
    19861 cggctccatg tccaggaaca ccaccggccc gccggccagc agtccacggg tgcgggcgtc
    19921 gagcaccgcc ccgccgccca gcgccaggac accggtgtgc tccgccaggg cggcgcggac
    19981 cgccgcccgc tccagttccc ggaagcgggc ctcgccctcc tcggcgaaga cgtcggcgac
    20041 cgtccgggcc cgcgcggcca cgatgtcggc gtcggtgtcc ctgaacggca gcccgagccg
    20101 tcccgcgagt atccggccga ccgtcgtctt gccgaccgcc atggggccga ccagaaccac
    20161 cgccggaccc ggcgcgcgcc ccgtcaccgc gcgccccgtc actgtacggc caggtggtcg
    20221 aggaacccgg tgacgttgcg gcgggtctcc ggcacggagt cgccgccgaa cttctcggcg
    20281 acggcgtcgg ccaggaccag ggcgaccatc gcctcggcga cgatcccggc ggccgggacc
    20341 gcgcacacgt cggagcgctg gtggtgcgcg cgggcggtgt caccggtggc gacgtcgacg
    20401 gtggccaggg cgcgcggcac ggtggcgatc ggcttcatcg ccgcccgcac cctgagtggt
    20461 tcgccggtac tcagcccgcc ctcggtgccg ccgctgcggc cggaggcccg gcgcactccg
    20521 tccggcgagg ggacgatctc gtcgtgcgcc cgggaaccgg gcacccgggc cagtgccgtc
    20581 ccgtccccga gctcgacggc cttgatggcc tggatgccca tcagggccgc cgccaggcgc
    20641 gcgtccagcc gccggtccca gtgcacatgg ctgccgagcc ccaccggcac cccgtgggcc
    20701 agcacctcca ccacaccgcc gagggtgtcg ccctcggccc gggccccgtc gatcgcggcg
    20761 accatccgcg cgctcgtgtc cgggtccagg caccgcaccg ggtccgcgtc cagccgcgcg
    20821 gtgtcccgtg gcgcgggcag cagcccgtac ggggcggcga ccgcccccag ctcgacgacg
    20881 tgcgagacga tctcgacgcc ggcggtcgcg cggaggtagg accgggccac cgcgcccagc
    20941 gcgaccctgg ccgcggtctc ccgggcactg gcccgctcca gcaccggccg cgcctcgggg
    21001 aagccgtact tctgcatgcc cgccaggtcg gcgtggcccg ggcgggggcg ggtgagcggg
    21061 gcgttgcgcg ccaggccggc caggacctcc ggggccaccg gatcggccgc catgacctgc
    21121 tgccacttgg gccactcggt gttcgcgacc atgacggcca cgggggagcc cagggtcagc
    21181 ccgtgccgta cgccgccgag gaaggtgacc tcgtcgcgct cgaaggtcat ccgggcgccg
    21241 cggccgtggc ccagtctgcg ccgcgccagc gcgtcgctca ccatcctctt cgtcaccggg
    21301 acaccggagg gcagtccctc cagggtcgcg acgagtgcgg ggccgtgcga ctcaccggcc
    21361 gtcagccaac gcagactgct caacgacgct ctcctcacgg gttcgacagc ggtgcgggcg
    21421 gggggatcag accagcggac cgctcgtcgc ggacagcggc cgtgccggac ggcgctcgcg
    21481 cgtcccgagg aactcggaga cgaggaaggc caggtcgagg gactgactcc ggttcagccg
    21541 ggggtcgcac accgactcgt agcgcgaggc caggtcctcg aagagcacct cgtgcccgcc
    21601 gcccacgcac tcggtgacgt cgttgccggt gaactccacg tggatgccgc cgggatgggt
    21661 gcccagggag tggtggacgt cgaagaagcc ccggatctcg tcgagcacgt cgtcgaagcg
    21721 ccgggtcttg tgaccggacg gggcctccag cgtgttcccg tgcatggggt cgcacaccca
    21781 ggcgaccttc gctcccgagg cggtgacctt ctccaccagc gggggcagcg cgtcctgcac
    21841 cttgtccgcg cccatgcgga cgacgagggt gagccggccc ggctcgcgct tcgggtccag
    21901 ccggtcgatc agctgcagca cggtgtcggc gtcggccttc gggccgagct tcaccgcgat
    21961 cgggttgttg atccgggaga agtactcgac gtgggcaccg gagaggtccc gggtccgctc
    22021 accgatccac agcatgtgcc ccgaggtcgc gtagggcagc ccggtgaagg tgtcgacgcg
    22081 ggtgagcgcg gcctcgtagt ccaggagcag cccctcgtgg gagacgaaga actcctcggc
    22141 gtccgccccg cccggcccgc cggtggcgtg catgaagcgc agcgcccggt cgatctcgtc
    22201 ggcgatggac tcgtagcggt gcccggaggg cgacccggag acgaagtccc gcgtcaggtc
    22261 gtggatctgg cgcaggttcg cgtccccgcc cgaggtgaag gcgcggacca ggttcagcgt
    22321 cgtcaccgac gcctggtaca tcgtcagcag ccgggccggg tccgggacgc gggagtcctc
    22381 ggtgaactcg aagccgttga ccgcgtcgcc ccggtagacc ggcagcacga ccccgtcccg
    22441 ggtctcggtc ggcttcgaac gcggcttggc gtactgcccg gcgagccgcc cgaccttcac
    22501 gacggggacc gagctcgcgt aggacagcac caccgccatc tgcagcaggg tgctgagctt
    22561 gtcccgcgtg gtgtccgccc ggaccccgtc gaaggtctcc gcgcagtcac cgccctgcag
    22621 caggaacgcc tcgccgaggg ccacggcggc cagccggtcc ttgagacggt cgcactcgcc
    22681 ggcgaagacc agagggggaa gggtctccag cttccgcgtg acggcgtcga gggcggaccg
    22741 gtcgggccag tccggctgct gggcggccgg gtacgtacgc aaggagtccc gggctgaggc
    22801 gttccccgag gccatgggac tgcccttcag gaatgagcgc atgtcatgcc ttcacttcct
    22861 tgtgtcagtc ttgtgtcagg aatgatcaga ggtctctttt tcctgccggc ggcccatttc
    22921 ttccgtgacc caccagtcgg ccggtatgtg tttccgcggg tgtccgcgcg gtccgccgaa
    22981 ttcacggatg ccggaggtcc ggtaccggac agggacggct tcaccggtgc ccggaccgtc
    23041 gtgtccacca ccggtgcgca tcacgtggtc gggggccgaa cgagaacacc acgagtcccg
    23101 cgggccgggc catgagtggc atctactcag ttcacggccg cggtgaccgg ccgggcggcc
    23161 gggccggtcc ggcggaccgg gtgagggacc gggcgccgcc aaccggcgag attctccagt
    23221 tggacagccg tgccgcggcc cggtggggcc ggctgtccaa tgagctccgt tgacatgcgc
    23281 agggacggtc aattagaaag tcctggcagg ccgcgaaaag ctatgggaga aaaaagtgga
    23341 ctctcagccg gagccgcagg attccttaac cgacctttct gggaaagaaa gtccccggcc
    23401 atcggccacg gacacggagc gggcgatcgc agaaatatgg tcggaggttc tggaagagcg
    23461 tcaggtgggt cccgaggaca atttcttcga cctcggcggg cattcggtgc tgctgcacct
    23521 ggtccaggac cggatcaccg aggagctggg caggaagccg tccctggtcg acctgttcac
    23581 gtacacgacg gtccgggcgc tggcccgtca cctcgacggc gacacggccg gacccgcccg
    23641 ctccgggagc gcggcggaac gggccggcgg gcgcgcgcga ctccagcagc gcgcccggcg
    23701 gacccggtcg gccgcgcggg accagggtgg gacaggtgag tgacgacgga ctcggcgagc
    23761 cggcggacga cgccgagcac atcgccgtca tcggcatggc ggcccggttc cccggcgccg
    23821 aggacatcgg gcagttctgg cgcaacctca ccgacggcct ggacaccgtg acccgctcgg
    23881 atccgcggcc ggtcccgggc ggcggtccca cccgctcgta cgtaccggcc cgcggcctgc
    23941 tccgggaacc ggagtggttc gacgcggact acttcggcta ctcaccccgt gaggcccgga
    24001 tcatcgaccc ccagcaccgg gtcctgctgg agtgcgcggt ccaggccctg gaacacgccg
    24061 gccacgaccc ggcccggtac cccggagcca tcggcgtcta cggcggcggc accgccaccc
    24121 gctacgccga gctggcgagg tcgggggcgg acagcgtgtc gggggcgacc gacatggaga
    24181 tcctgctggg caacgcgaac gactacctgg tcacgcggat cgcctacaag ctggggctgc
    24241 gcggcccggc cgtcacggtg caggcggcgt gcgccacctc gctcgtcgcc gtccacacgg
    24301 ccgtccaggc cctgctctcc ggcgactgcg acatggccct ggccggcggc gccgccgtgc
    24361 acgtcccggc gcggaacagc ccttacgcgg agggcgggat cctgtccgcg gacgggttct
    24421 gccggacctt cgacgcggcc gcgggcggca ccgtgggcgg cgacggcgtg ggcgtcgtgg
    24481 tcctcaaacg gctcgcggac gccctgtcgg acggcgacca cgtccacgcc gtgctgcgcg
    24541 gcacggcggt gaacaacgac ggctccggac ggatcggctt caccgccccc agcgtcgacg
    24601 ggcaggccgc cgtcgtccgg gacgcgctgt ccgtggccgg ggtggacccc gccaccgtca
    24661 cctatgtgga ggcccacggc accgccacgc cgctcggcga ccccatcgag gtggcggcgc
    24721 tgaccaaggc gttccgggac ggcaccgacc gcagcgggtt ctgccggatc ggatcggtca
    24781 agacgaacat cgggcacacc gacgccgccg ccggcgcggc gggcctgatc aagacggtcc
    24841 tcgccctgga gcacgccacc atcccgccga gcctgcacta cggcgaaccc aacccgcgga
    24901 tcgacttcgc cgccaccccc ttccgggtgg ccgaccgcct ggaggaatgg cgcccgccgg
    24961 cgggcacccc ccggcgggcg ggggtcagtt ccttcggtat cggcggcacc aacgcccatg
    25021 tcgtcctgga ggaggccccc gccgccgcgc cggcggaacc cgccgccccc tggcagctgc
    25081 tggtcctctc ggcccgcacc ccgaccgccc tggaggcggt cacggagaac ctcgccgccc
    25141 atctggacgc gcaccccgag gtgccggtcg ccgacgtggc gtggacgctc caggccggac
    25201 gccgccggca cggccaccgc aggtacgcgg tcgtcgcggg gacaccggac gccgtacggg
    25261 cgctgtccgg cacggacgga cgcctggccg gctccgacgg ccccccggtg ccccggccgg
    25321 tgacgttcct gttccccggc accggagcgc ccggtgaagc cgggcggctc cacacggagc
    25381 accgggcctt ccgccgcgcc ttcgacgcct gccgcaccgc ggcacgcgac atcgagggcg
    25441 tcgacgtgcg ggacctccgg cccggcgtgc ggcccgccga cccggttgcg gccgaactgc
    25501 tcgccttcgc cgaggagtac gcgctggcac ggacgctgac cgcgtggggc gtgcgcccgg
    25561 cctcggtgct cggcacgggc gtgggcgtgt tcacggccgc cgcggtggcc ggtgtgttct
    25621 ccgtccggga cgcgatccgg ctggtggcgg aacggacccg gctgctcggc gcggccggtg
    25681 ccgagcccgc ggcggacggc gtggccgcgg cggacggtgt ggccgcggcg gacggcgtgg
    25741 cccgcttcga ggaactcgtc cgtgaggccg gcccccgggt ccccggcatc cccctcgtcc
    25801 gcgcgacggc ccccggggac tggtccgcgt acctgcgcgg ggaggacgag tggcaccgcg
    25861 ccctcgacct ggtgctggag gactcccggt ccgtcctggt cgagaccggc gcggggagcg
    25921 ctctggacgc cgcccggcgg cgtcccggac acacggacga ccacctgctc gtggcgcccc
    25981 tggccggaga ggccgaggcc gacgggcctc ccgcgctgct caccgcgctg ggggacctgt
    26041 ggctggcggg cacggaggtc tcctgggccg aggtccatgc ggcccgcagg ctccgggttc
    26101 cgctgccgac gtacccgttc gaacggcggc ggcacctcgt ggcggcggcc gaaccggaac
    26161 gtgtgtccgc cggcgccgag gaggccgtcg cgcccgacgg cgcgagcggg agcggcaacg
    26221 gcaacgggaa cggtccggaa ggggggagcg acggggcgag taccgcggac cgggttgccc
    26281 ggctgttcgc gcagaccctc ggcctcgccg acgtcgcccc cgagaacagt ttcttcgacc
    26341 tcggcggcga ctcgctcata gccgtccagc tgctgtcccg cgcccgtgag gacttcggcg
    26401 tggagatcga cgtcctggcg ctgtacgacg ccgagacggt gaccgagttc gccgcactcg
    26461 tggacacgct cgcaggcggt cacgacagcc cgccgcacac cccttcctga ggagccgtca
    26521 cagtggatgg aaagcagtcc gtcgccggtg cgtcccgtac ggcgtcgggg aaaccgtggc
    26581 tggtgggccg tgagcgcggg ccggcggcca ccgccaccct gtactgcttc acccccgcgg
    26641 gcggggcgcc cggcgagtac gtacggtggt ccgacgacct gccggacgtc caggtgtggg
    26701 cggtgcaact gccgggccgg gcctcccgcc gggccgaacc tccctaccgg aggatggagc
    26761 cgctggtcga cgcgctggtg gaacaggtgg tcttcgagcc gccgttcgcg ttcttcgggc
    26821 acagcctcgg cgggctggtc gccttcgagg tggcccgggc cctgcgcgac cgcggccggg
    26881 agcagccgga gcggctgttc ctgtcctcgg cggtgccgcc ccccgtcgtc ctcaccggcc
    26941 cgccgctgca cacgctctcc gacgccgacc tgctctccgc ggtggagcgc cgatgggggc
    27001 cgctgccggg gccggtccgc gagaaccccg cgctgctgga gatcttgctc gcctactacc
    27061 gggccgacct cgaactgttc gagacgtacg accaccgccc cggcgaaccg ctcgaccgcc
    27121 cgatcacggc cttcgccggc accgaggagc gggacaccct cgacatcgag ggctggcagg
    27181 cctacaccag cgccccgttc gatccgcacc acctgcccgg agggcacttc tacctccggg
    27241 cggagcggcg cgaactgctg cgcagggtgg ccgcatcgat gccggggccc cgggcgcccc
    27301 gaggacaaca gtgacgggag tcgccatgcg gtacacgacc ttcggccgtg gcacgggcct
    27361 gcgggtgtcg gagtacggac tgggcacggt caacttcggc accggctggg gcggtggggc
    27421 cgagcccgac gaggcgcgca aggtgttcga ccggttcgcc gaggcgggcg gcacactgat
    27481 cgacaccgcc gactgctacc agttcggcca ggcggaggag ctgctgggcg acttcctcgc
    27541 cgccgaccgc gaccacttcg tggtggcgac caagttcggc tacggatccg ccccgcagcc
    27601 gcggatctcc gggaccggca acagccgcaa gaacatcgtc cggtcggtgg aggcgagcct
    27661 gaaacggctg tccaccgatt acgtcgacct gtactgggcg cacttccccg acacggtcac
    27721 gcccacggag gagatcctcg ccgccctgga cgacctggtg cgggccggga agatcctgca
    27781 cgtgggcctc tccaacttcc ccgcctggca ggtctcccgg gcggtgaccg tcgcggagta
    27841 ccggcaccag gcgccggtcg tggccgtcca gaccgagtac agcctggccg accgcaccgc
    27901 cgagcgggaa ctgctgccca tggcggagag cctcggcctg ggcgtcgggc tctggtcgcc
    27961 gctgggcggc gggctgctga cgggcaagta ccgctccggc gccgaggggc ggctcaccga
    28021 ctggaagggc cgggtgatcc gcaccgagaa cgacgaccgg cggaccgccg tcctcgacac
    28081 cgtgatcgcc gtcgcggagg aatccgggac gcccgcctca caggtctcgg tcgcctgggt
    28141 gcgggagagg gcccggcgtg cccgcaccgc cttcgtgccc gtcatcgggc cgcgctcggt
    28201 ggcccagctc gacgactacc tggccgccct cgacgtcgag ctgaccgacg gacagctcgc
    28261 ccgtctggac gaggccagtg ccgtgccgct cggctcgccc cacgaggtga gcgcagccgc
    28321 cctggggcgg gtgctcggcg gcgacgccgg acgtgtacgg ggcggggacg tcccggtcgc
    28381 atgaggcgtc gcacgaggcg cgatcccagc cgcggccatg gccatgacca tgactgcggt
    28441 cgtgaagacg gagtcggaca ggaagggcgg accggagcat gacggcgagc gaactcatcg
    28501 gggtgtggcg gctggcgtcg ttccacgacg tcgacgagga ggggaggaca caggaggggc
    28561 cgctgggccc cgaacccgac ggactgctct tctactccgc cgaggggcac gtgtccgtgc
    28621 acatgatgcg tacaggaccg caggccggcc cccgggcgtc ccgcggtggc tccggggagc
    28681 ggccgccaca ggactacatg agctactcgg gcacctggcg gcgcgccggt gaccaggtcg
    28741 tccacacgat cacggtcgcc ccggagcggg gctggatcgg gaccgaccag gtccgggacc
    28801 tgtccctggc cggcgacacg ctcacgctgc acggcgactc gctgatcgga cgcaggcagc
    28861 gcagggtgct ggtctggcgg cgcgtcagcg gggaggcggg gccggggcgt ccgtgaccgt
    28921 gccgtgcccg tgagccgacc gggggcgggg atccgccggg gcgctcccgg gctccgccgt
    28981 ggcggcgcgc acgcggctga tgaacgcccg tgtggccgga ctgaccgggc cttcgaggcg
    29041 ccagccgagg gcgacctggc cgcgcagctc ggggtgggcg aaggggatcg cgcacaaccg
    29101 cgccggatgg gacctggcca gggactccgg gaggagggcc acgcccaggc cccagccggc
    29161 cagctccgcg agggtgctcg ggttcccggc ctcgaagccg atccgcgggg tgatgccggc
    29221 cttggcgcag accgcgtcga ggctcgtgcg catgccggtg cccgggggca ggctgatcag
    29281 ggtgcggtcc cggatgtcgt ccagggtgat ctccttgcgg gtggccaggg gatcgcccgg
    29341 gctcacggtg gcgaccagcc gctcgtccgc caccacgtgc gtcgccaggc ccgtgggccc
    29401 cggtccggcg ctgcccggca gcgcgacgaa cgccgcgtcg agccggccgt cccgcagcga
    29461 ctcgatcatc gtctccgagt tcccctccga gagggtgatc tccaccgacg ggtggtcctg
    29521 gtggaactcg gcgagcagcg cgggcaggtc gaaccccccg caggccggca ccatcccgat
    29581 cgcgacgtgc ccgcgcagca gaccggtcag ctcgtcgacg accagccggg tgtcggtgat
    29641 cgccgtgagc gcggcgcggg cgtaggggag cacggccgcg cccacctcgg tcggccgcac
    29701 cagacgtccg gaacggtcca gcagctcctg gcccagcttg cgctccagtc ggcggatctg
    29761 tgcgctcacc cccggctgcg cgacgtgcag ccgggcggcc gccttggtga aactcgcttc
    29821 ctcgaccacg gctacgaagt actccaactg cctcagctcc ataaccaatg attctagcaa
    29881 ggatgcattc cagatct
//
