BGC0000937: fosfazinomycin A biosynthetic gene cluster from Streptomyces sp. WM6372
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Location: 9,914 - 33,560 nt. (total: 23,647 nt).
This entry is originally from NCBI GenBank KF386865.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
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History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000937
Short description fosfazinomycin A biosynthetic gene cluster from Streptomyces sp. WM6372
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: incomplete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Other
Loci NCBI GenBank: KF386865.1
Compounds
  • fosfazinomycin A
  • fosfazinomycin B
Species Streptomyces sp. WM6372 [taxonomy]
References
Chemical products information
fosfazinomycin A
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C15H32N7O7P1
Chemical database entries
PubCHEM
fosfazinomycin B
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C10H23N6O6P1
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AGZ93896.1
 9914 - 12097 (+) asparagine synthetase
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  • AGZ93897.1
 12124 - 12825 (+) methyltransferase type 11
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  • AGZ93898.1
 12825 - 13679 (+) PEP mutase
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  • AGZ93899.1
 13676 - 14812 (+) phosphonopyruvate decarboxylase
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  • AGZ93900.1
 14809 - 15570 (+) metallophosphoesterase
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  • AGZ93901.1
 15658 - 17055 (+) methylcrotonyl-CoA carboxylase alpha subunit
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  • AGZ93902.1
 17062 - 18015 (+) 2-ketoglutarate dependent dioxygenase
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  • AGZ93903.1
 18012 - 19061 (+) methyltransferase small
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  • AGZ93904.1
 19114 - 20394 (+) hypothetical protein
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  • AGZ93905.1
 20426 - 21661 (-) major facilitator superfamily MFS_1
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  • AGZ93906.1
 21661 - 22356 (-) thymidylate kinase-like protein
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  • AGZ93907.1
 22406 - 23884 (-) 3-carboxy-ciscis-muconate cycloisomerase
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  • AGZ93908.1
 23884 - 25851 (-) hypothetical protein
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  • AGZ93909.1
 25829 - 27388 (-) glutamine synthetase family protein
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  • AGZ93910.1
 27385 - 28887 (-) amidase
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  • AGZ93911.1
 28877 - 30604 (-) hypothetical protein
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  • AGZ93912.1
 30680 - 31084 (-) GCN5-related N-acetyltransferase
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  • AGZ93913.1
 31071 - 32378 (-) adenylosuccinate lyase
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  • AGZ93914.1
 32535 - 33560 (-) transcriptional regulator
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: 3MLJYPZS4D4TV7XCS2U44ZHE, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Update compound, loci and subcluster information
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Hidden contributor (ID: 3UOU7PODQJXIM6BEPUHHRRA5, no GDPR consent given).
  • Hidden contributor (ID: H5KVDLSVQ3TJW7SKCDNBDEVC, no GDPR consent given).
  • Fixed gene accessions
  • Fix DOI
  • Add new compound: fosfazinomycin B
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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