BGC0000937: fosfazinomycin A biosynthetic gene cluster from Streptomyces sp. WM6372
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Location: 9,914 - 33,560 nt. (total: 23,647 nt).
This entry is originally from NCBI GenBank KF386865.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000937
Short description fosfazinomycin A biosynthetic gene cluster from Streptomyces sp. WM6372
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: partial
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
KF386865.1
9914 - 33560
via
Compounds
  • fosfazinomycin A
  • fosfazinomycin B
Species Streptomyces sp. WM6372 [taxonomy]
References
Chemical products information
fosfazinomycin A Evidence: NMR, Mass spectrometry
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C15H32N7O7P1
Chemical database entries
PubCHEM
fosfazinomycin B Evidence:
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C10H23N6O6P1
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AGZ93896.1
 9914 - 12097 (+) asparagine synthetase
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    • AGZ93897.1
    		 12124 - 12825 (+) methyltransferase type 11
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      • AGZ93898.1
      		 12825 - 13679 (+) PEP mutase
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        • AGZ93899.1
        		 13676 - 14812 (+) phosphonopyruvate decarboxylase
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          • AGZ93900.1
          		 14809 - 15570 (+) metallophosphoesterase
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            • AGZ93901.1
            		 15658 - 17055 (+) methylcrotonyl-CoA carboxylase alpha subunit
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              • AGZ93902.1
              		 17062 - 18015 (+) 2-ketoglutarate dependent dioxygenase
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                • AGZ93903.1
                		 18012 - 19061 (+) methyltransferase small
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                  • AGZ93904.1
                  		 19114 - 20394 (+) hypothetical protein
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                    • AGZ93905.1
                    		 20426 - 21661 (-) major facilitator superfamily MFS_1
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                      • AGZ93906.1
                      		 21661 - 22356 (-) thymidylate kinase-like protein
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                        • AGZ93907.1
                        		 22406 - 23884 (-) 3-carboxy-ciscis-muconate cycloisomerase
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                          • AGZ93908.1
                          		 23884 - 25851 (-) hypothetical protein
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                            • AGZ93909.1
                            		 25829 - 27388 (-) glutamine synthetase family protein
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                              • AGZ93910.1
                              		 27385 - 28887 (-) amidase
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                                • AGZ93911.1
                                		 28877 - 30604 (-) hypothetical protein
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                                  • AGZ93912.1
                                  		 30680 - 31084 (-) GCN5-related N-acetyltransferase
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                                    • AGZ93913.1
                                    		 31071 - 32378 (-) adenylosuccinate lyase
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                                      • AGZ93914.1
                                      		 32535 - 33560 (-) transcriptional regulator
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                                        Biosynthesis information
                                        Annotation changelog

                                        Entry version: 4

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2022-10-07
                                        Update chemical activity to schema version 2.11
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 3

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2022-09-15
                                        Fixed gene accessions
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        2022-09-15
                                        Fix DOI
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        2022-09-15
                                        Add new compound: fosfazinomycin B
                                        • (ID: 3UOU7PODQJXIM6BEPUHHRRA5)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        2022-09-15
                                        Updated bioactivity data
                                        • (ID: H5KVDLSVQ3TJW7SKCDNBDEVC)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 2

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2019-10-16
                                        Migrated from v1.4
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        2019-10-16
                                        Update compound, loci and subcluster information
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 1

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2015-06-12
                                        Submitted
                                        • (ID: 3MLJYPZS4D4TV7XCS2U44ZHE)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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