BGC0000940: desferrioxamin B biosynthetic gene cluster from Streptomyces coelicolor A3(2)
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Location: 3,033,355 - 3,040,682 nt. (total: 7,328 nt).
This entry is originally from NCBI GenBank AL645882.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000940
Short description desferrioxamin B biosynthetic gene cluster from Streptomyces coelicolor A3(2)
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
AL645882.2
3033355 - 3040682
via Knock-out studies, Enzymatic assays
Compounds
  • desferrioxamin B
  • desferrioxamine E
Species Streptomyces coelicolor A3(2) [taxonomy]
References
Chemical products information
desferrioxamin B Evidence:
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C25H48N6O8
Chemical database entries
NPAtlas
desferrioxamine E Evidence:
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C27H48N6O9
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAB87217.1
  • SCO2780
 3033355 - 3034404 (+) Ferric-siderophore lipoprotein receptor
  • Transport
  • Knock-out
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  • CAB87218.1
  • SCO2781
 3034632 - 3035477 (+) Ferric-siderophore hydrolase
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    • CAB87219.1
    • SCO2782
    		 3035641 - 3037083 (+) putative pyridoxal-dependent decarboxylase
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      • CAB87220.1
      • SCO2783
      		 3037106 - 3038347 (+) putative monooxygenase
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        • CAB87221.1
        • SCO2784
        		 3038344 - 3038898 (+) Acyl CoA acyl transferase
        • Scaffold biosynthesis
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        • CAB87222.1
        • SCO2785
        		 3038895 - 3040682 (+) ATP-dependent siderophore synthetase (IucA-IucC family)
        • Scaffold biosynthesis
        • Knock-out Activity assay
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        Biosynthesis information
        Annotation changelog

        Entry version: 4

        Date
        Changes
        Submitters
        Reviewers
        2022-10-07
        Update chemical activity to schema version 2.11
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 3

        Date
        Changes
        Submitters
        Reviewers
        2022-09-15
        Updated bioactivity data
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 2

        Date
        Changes
        Submitters
        Reviewers
        2019-10-16
        Migrated from v1.4
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        2019-10-16
        Updated compound(s) information (NPAtlas curation)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 1

        Date
        Changes
        Submitters
        Reviewers
        2015-06-12
        Submitted
        • (ID: TQLOJWF4PZL7W4TCL4J4Z4SZ)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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