Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000944.1:
Cluster 1Other16093

BGC0000944, staphyloferrin biosynthetic gene cluster from Staphylococcus aureus. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: Staphyloferrin A
SMILES string: Copy to clipboard
Molecular formula: C17 H24 N2 O14
Exact molecular mass: 479.1 Da ([M-H]-)
Molecular activity: Siderophore
Molecular target: Iron

Class-specific details

Biosynthetic class(es):
Other
Other biosynthetic class:
Non-NRP siderophore

Gene cluster description

staphyloferrin (BGC0000944). Gene Cluster 1. Biosynthetic class = Other. GenBank CP000253, positions 257890-263982. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Knock-out studies, Enzymatic assays, Heterologous expression
MIxS-compliance:Unknown
Contact for this cluster:Carl Balibar (Merck)

Literature references

1. Cotton JL et al. (2009) Identification and characterization of the Staphylococcus aureus gene cluster coding for staphyloferrin A. Biochemistry 48(5):1025-35. doi: 10.1021/bi801844c.
2. Beasley FC et al. (2009) Characterization of staphyloferrin A biosynthetic and transport mutants in Staphylococcus aureus. Mol Microbiol 72(4):947-63. doi: 10.1111/j.1365-2958.2009.06698.x. Epub