BGC0000961: bactobolin biosynthetic gene cluster from Burkholderia thailandensis E264
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Location: 1,445,675 - 1,482,269 nt. (total: 36,595 nt).
This entry is originally from NCBI GenBank CP000085.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000961
Short description bactobolin biosynthetic gene cluster from Burkholderia thailandensis E264
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
CP000085.1
1445675 - 1482269
via
Compounds
  • bactobolin
Species Burkholderia thailandensis E264 [taxonomy]
References
Chemical products information
bactobolin Evidence:
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C14H20Cl2N2O6
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BTH_II1222
  • ABC34571.1
 1445675 - 1446820 (+) 4-hydroxyphenylpyruvate dioxygenase
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    • BTH_II1223
    • ABC36200.1
    		 1446810 - 1447106 (-) conserved hypothetical protein
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      • BTH_II1224
      • ABC35151.1
      		 1447197 - 1448120 (-) CmaB
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        • BTH_II1225
        • ABC35825.1
        		 1448266 - 1448511 (-) hypothetical phosphopantetheine-containing protein
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          • BTH_II1226
          • ABC34137.1
          		 1448529 - 1450175 (-) peptide synthetase, putative
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            • BTH_II1227
            • ABC34067.1
            		 1450117 - 1450737 (-) N-acyl homoserine lactone synthase
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              • BTH_II1228
              • ABC35966.1
              		 1450821 - 1451228 (-) conserved hypothetical protein
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                • BTH_II1229
                • ABC34499.1
                		 1451868 - 1453100 (+) sodium/hydrogen exchanger
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                  • BTH_II1230
                  • ABC35002.1
                  		 1453151 - 1454008 (+) hypothetical protein
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                    • BTH_II1231
                    • ABC34774.1
                    		 1454107 - 1454811 (-) autoinducer-binding transcriptional regulator, LuxR family
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                      • BTH_II1232
                      • ABC35159.1
                      		 1455361 - 1457442 (-) oligopeptidase A
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                        • BTH_II1233
                        • ABC34305.1
                        		 1457826 - 1462166 (+) peptide synthetase, putative
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                          • BTH_II1234
                          • ABC34108.1
                          		 1462174 - 1466748 (+) JamP
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                            • BTH_II1235
                            • ABC35027.1
                            		 1466630 - 1470742 (+) JamP
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                              • BTH_II1236
                              • ABC34483.1
                              		 1470782 - 1474216 (+) nonribosomal peptide synthetase, putative
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                                • BTH_II1237
                                • ABC34154.1
                                		 1474257 - 1476596 (+) thiotemplate mechanism natural product synthetase
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                                  • BTH_II1238
                                  • ABC35075.1
                                  		 1476609 - 1478201 (+) polyketide synthase
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                                    • BTH_II1239
                                    • ABC34220.1
                                    		 1478206 - 1479051 (+) acetyltransferase, GNAT family
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                                      • BTH_II1240
                                      • ABC35463.1
                                      		 1479032 - 1479874 (+) thioesterase II of alpha/beta hydrolase superfamily
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                                        • BTH_II1241
                                        • ABC36044.1
                                        		 1479935 - 1481161 (+) drug resistance transporter, Bcr/CflA family protein, putative
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                                          • BTH_II1242
                                          • ABC36162.1
                                          		 1481424 - 1482269 (-) dioxygenase, TauD/TfdA family
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                                            Biosynthesis information
                                            Annotation changelog

                                            Entry version: 4

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-10-07
                                            Update chemical activity to schema version 2.11
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 3

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-09-15
                                            Updated bioactivity data
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 2

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2019-10-16
                                            Migrated from v1.4
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            2019-10-16
                                            Updated compound(s) information (NPAtlas curation)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 1

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2015-06-12
                                            Submitted
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            Detailed domain annotation
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