BGC0000961: bactobolin biosynthetic gene cluster from Burkholderia thailandensis E264
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1,445,675 - 1,482,269 nt. (total: 36,595 nt).
This entry is originally from NCBI GenBank CP000085.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000961
Short description bactobolin biosynthetic gene cluster from Burkholderia thailandensis E264
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: CP000085.1
Compounds
  • bactobolin
Species Burkholderia thailandensis E264 [taxonomy]
References
Chemical products information
bactobolin
Copy SMILES
C14H20Cl2N2O6
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BTH_II1222
  • ABC34571.1
1445675 - 1446820 (+) 4-hydroxyphenylpyruvate dioxygenase
copy AA seq
copy Nt seq
  • BTH_II1223
  • ABC36200.1
1446810 - 1447106 (-) conserved hypothetical protein
copy AA seq
copy Nt seq
  • BTH_II1224
  • ABC35151.1
1447197 - 1448120 (-) CmaB
copy AA seq
copy Nt seq
  • BTH_II1225
  • ABC35825.1
1448266 - 1448511 (-) hypothetical phosphopantetheine-containing protein
copy AA seq
copy Nt seq
  • BTH_II1226
  • ABC34137.1
1448529 - 1450175 (-) peptide synthetase, putative
copy AA seq
copy Nt seq
  • BTH_II1227
  • ABC34067.1
1450117 - 1450737 (-) N-acyl homoserine lactone synthase
copy AA seq
copy Nt seq
  • BTH_II1228
  • ABC35966.1
1450821 - 1451228 (-) conserved hypothetical protein
copy AA seq
copy Nt seq
  • BTH_II1229
  • ABC34499.1
1451868 - 1453100 (+) sodium/hydrogen exchanger
copy AA seq
copy Nt seq
  • BTH_II1230
  • ABC35002.1
1453151 - 1454008 (+) hypothetical protein
copy AA seq
copy Nt seq
  • BTH_II1231
  • ABC34774.1
1454107 - 1454811 (-) autoinducer-binding transcriptional regulator, LuxR family
copy AA seq
copy Nt seq
  • BTH_II1232
  • ABC35159.1
1455361 - 1457442 (-) oligopeptidase A
copy AA seq
copy Nt seq
  • BTH_II1233
  • ABC34305.1
1457826 - 1462166 (+) peptide synthetase, putative
copy AA seq
copy Nt seq
  • BTH_II1234
  • ABC34108.1
1462174 - 1466748 (+) JamP
copy AA seq
copy Nt seq
  • BTH_II1235
  • ABC35027.1
1466630 - 1470742 (+) JamP
copy AA seq
copy Nt seq
  • BTH_II1236
  • ABC34483.1
1470782 - 1474216 (+) nonribosomal peptide synthetase, putative
copy AA seq
copy Nt seq
  • BTH_II1237
  • ABC34154.1
1474257 - 1476596 (+) thiotemplate mechanism natural product synthetase
copy AA seq
copy Nt seq
  • BTH_II1238
  • ABC35075.1
1476609 - 1478201 (+) polyketide synthase
copy AA seq
copy Nt seq
  • BTH_II1239
  • ABC34220.1
1478206 - 1479051 (+) acetyltransferase, GNAT family
copy AA seq
copy Nt seq
  • BTH_II1240
  • ABC35463.1
1479032 - 1479874 (+) thioesterase II of alpha/beta hydrolase superfamily
copy AA seq
copy Nt seq
  • BTH_II1241
  • ABC36044.1
1479935 - 1481161 (+) drug resistance transporter, Bcr/CflA family protein, putative
copy AA seq
copy Nt seq
  • BTH_II1242
  • ABC36162.1
1481424 - 1482269 (-) dioxygenase, TauD/TfdA family
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.