LOCUS       BGC0000962             40156 bp    DNA     linear   BCT 03-OCT-2002
DEFINITION  Lyngbya majuscula barbamide biosynthesis gene cluster, complete
            sequence.
ACCESSION   BGC0000962
VERSION     BGC0000962
KEYWORDS    .
SOURCE      Lyngbya majuscula
  ORGANISM  Lyngbya majuscula
            Bacteria; Cyanobacteria; Oscillatoriophycideae; Oscillatoriales;
            Oscillatoriaceae; Lyngbya.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 21:15:26
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 40156
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..40156
                     /db_xref="taxon:158786"
                     /mol_type="genomic DNA"
                     /organism="Lyngbya majuscula"
     subregion       1..40156
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="NRP, Polyketide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..40156
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            5531..5818
                     /gene="barA"
     CDS             5531..5818
                     /NRPS_PKS="Domain: PCP (19-88). E-value: 2.9e-17. Score:
                     54.5. Matches aSDomain: nrpspksdomains_barA_PCP.1"
                     /codon_start=1
                     /function="probably involved in the activation of leucine
                     to iniciate barbamide biosynthesis"
                     /gene="barA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /note="peptidyl carrier protein"
                     /product="BarA"
                     /protein_id="AAN32974.1"
                     /sec_met_domain="PP-binding (E-value: 5.2e-14, bitscore:
                     42.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNSTELPISDVVVPQTETEKQLAEIWKDVLSVETISIEDRFMDI
                     GGNSINLVEVVNQVTEKMGVSIKARWFFDKHKSTIAELSKEIDAVREQTH"
     aSDomain        5588..5794
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barA_PCP.1"
                     /evalue="2.90E-17"
                     /label="barA_PCP.1"
                     /locus_tag="barA"
                     /protein_end="88"
                     /protein_start="19"
                     /score="54.5"
                     /tool="antismash"
                     /translation="EKQLAEIWKDVLSVETISIEDRFMDIGGNSINLVEVVNQVTEKMG
                     VSIKARWFFDKHKSTIAELSKEID"
     gene            5850..6752
                     /gene="barB1"
     CDS             5850..6752
                     /codon_start=1
                     /function="probably related to chlorination"
                     /gene="barB1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /note="similar to the syringomycin SyrB2 protein and the
                     coronamic acid CmaB protein"
                     /product="BarB1"
                     /protein_id="AAN32975.1"
                     /sec_met_domain="PhyH (E-value: 3.3e-36, bitscore: 115.2,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTRAKAELSYYLSVEEKQFFRDNGYIGPFTLFQPEEILELWNEI
                     RMDLLDRETAPFPNSKMNYDRHLDIQALSDIISHPKIAHRVSSLLGSNVLCWRTAWFPK
                     YPGDEGTDWHQAESFVEFEGKSKLVPTESHDGPWELTAWVAFSEATRENGCMKVMPGTH
                     NTWYFDEHRNIEFEPDKINQKLTGGKKTGVYGYDYYKLKLDPNWEPDESQAVHLEMEPG
                     QFILFTSRCMHGSEPNTSGSSIRYGWSTRFVPTDVRVYPDWESFQHFGEVFPLERYATV
                     LVAGEDTYKHNKIRRPLGQ"
     gene            6812..7705
                     /gene="barB2"
     CDS             6812..7705
                     /codon_start=1
                     /function="probably related to chlorination"
                     /gene="barB2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /note="similar to BarB1, syringomycin SyrB2 protein and the
                     coronamic acid CmaB protein"
                     /product="BarB2"
                     /protein_id="AAN32976.1"
                     /sec_met_domain="PhyH (E-value: 5.5e-35, bitscore: 111.2,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTITAEPRYYLSVEEKQFFQENGYIGPFTLFPPEEMLELWYGIK
                     MDLLDKETAPFPNNKMNYDRHLDIKALNDIISHPKVVDRVSSILGPNVLCWRTEWFPKY
                     PGDEGTDWHQAESFVEFEGESKLVPTESHDGPWELTAWVTFSEATRKNGCMKVMPGTHT
                     TWYFDEHRNIKFEPDNINQKLTKGQKSGFYGYDYDKLKLDPNWEPDESQAVHLEMEPGQ
                     FFLFTSRCMHGSEPNTSESSIRYGWSTRFVSTDVRVYPDWDSFEHFGEKFMLDRYSTVL
                     VAGEDTYKHNKVRQPL"
     gene            7859..8665
                     /gene="barC"
     CDS             7859..8665
                     /NRPS_PKS="Domain: Thioesterase (22-247). E-value: 4.2e-50.
                     Score: 163.1. Matches aSDomain:
                     nrpspksdomains_barC_Thioesterase.1"
                     /codon_start=1
                     /function="proofreading or editing role or chlorination
                     role"
                     /gene="barC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 251; E-value: 1.4e-76)"
                     /gene_kind="biosynthetic-additional"
                     /note="thioesterase II"
                     /product="BarC"
                     /protein_id="AAN32977.1"
                     /transl_table=11
                     /translation="MQTDDSSWLIFDETPKCEASKMRLFCFHYAGAGGSIFQDWSRALP
                     DEVELVAIQLPGREKRCYEPLMSNIEDINLVLAQELSPFLSKPFAFMGHSMGALIAFDL
                     IRLLRQQELGQPQFLMVSGFDAPQLRPKESSNMHQLPDDEFAQAIRDYNGIPQVIAQNE
                     ELFELLLPRLRSDIKLGETYIYKDEEPLDCRIIALYSTEDSFVSKSGMYSWQEQTKGEF
                     ELYTFPGDHFFLHSAEELVLNTICTELQRYIKANDNCSTKVALQKS"
     aSDomain        7925..8599
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barC_Thioesterase.1"
                     /evalue="4.20E-50"
                     /label="barC_Thioesterase.1"
                     /locus_tag="barC"
                     /protein_end="247"
                     /protein_start="22"
                     /score="163.1"
                     /tool="antismash"
                     /translation="RLFCFHYAGAGGSIFQDWSRALPDEVELVAIQLPGREKRCYEPLM
                     SNIEDINLVLAQELSPFLSKPFAFMGHSMGALIAFDLIRLLRQQELGQPQFLMVSGFDA
                     PQLRPKESSNMHQLPDDEFAQAIRDYNGIPQVIAQNEELFELLLPRLRSDIKLGETYIY
                     KDEEPLDCRIIALYSTEDSFVSKSGMYSWQEQTKGEFELYTFPGDHFFLHSAEELVLNT
                     ICT"
     CDS_motif       8120..8179
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barC_0001"
                     /evalue="1.50E-05"
                     /label="NRPS-te1"
                     /locus_tag="barC"
                     /protein_end="107"
                     /protein_start="87"
                     /score="17.5"
                     /tool="antismash"
                     /translation="PFAFMGHSMGALIAFDLIRL"
     gene            8700..10253
                     /gene="barD"
     CDS             8700..10253
                     /NRPS_PKS="Domain: AMP-binding (10-411). E-value: 1.8e-91.
                     Score: 298.6. Matches aSDomain:
                     nrpspksdomains_barD_AMP-binding.1"
                     /codon_start=1
                     /function="adenylation; involved in activation of leucine"
                     /gene="barD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     309.2; E-value: 7e-94)"
                     /gene_kind="biosynthetic-additional"
                     /note="sequence similar to adenylation domains of NRPS"
                     /product="BarD"
                     /protein_id="AAN32978.1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-96, bitscore:
                     313.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKNIANLVTRHSKKSPHKCAITDGQTELSYGVWEAASNRFARKL
                     IEMGCQKGDRVVVLASKQTILMVGILGIFKAGCIHVPLDGKMPVNRLNKIITEIIPSVI
                     LTDQELLHLVSENVPQEVKIVLIEQLHPLITDSTVEEKDRLPQIESEDIAYCIYTSGST
                     GDPKGVLIKHGSVIDFFEGTREFYDVDEDSRCVSFSPFHFDASVIDILFPLYQGAWLYL
                     YSDVVLHELLFEVIKNNSVTHFAAFGSMLGLIAQTKEFDDVILKDLKTILTGADVPDIK
                     VIQKWLGKGENIKIINGYGPTEGTCACAAYIIRDRDPNRRELYPIGKPLKNAKLYLVDQ
                     QNQEIYDPEIPGELLIGGTQVMAGYWNREQQSKERLVEFKGTTCYKTGDICKYLADGNL
                     FFVGRNDNEVNVGGYRVHLNGIKQVINRFHWVENSEVVTLESKYGEKMLAAALMLANET
                     SKDSALKQIKEHLNQELPQYMVPRQIVVMEKFPQLSSGKTDRKTLSSILERDLLASKVH
                     "
     aSDomain        8730..9932
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barD_AMP-binding.1"
                     /evalue="1.80E-91"
                     /label="barD_AMP-binding.1"
                     /locus_tag="barD"
                     /protein_end="411"
                     /protein_start="10"
                     /score="298.6"
                     /tool="antismash"
                     /translation="RHSKKSPHKCAITDGQTELSYGVWEAASNRFARKLIEMGCQKGDR
                     VVVLASKQTILMVGILGIFKAGCIHVPLDGKMPVNRLNKIITEIIPSVILTDQELLHLV
                     SENVPQEVKIVLIEQLHPLITDSTVEEKDRLPQIESEDIAYCIYTSGSTGDPKGVLIKH
                     GSVIDFFEGTREFYDVDEDSRCVSFSPFHFDASVIDILFPLYQGAWLYLYSDVVLHELL
                     FEVIKNNSVTHFAAFGSMLGLIAQTKEFDDVILKDLKTILTGADVPDIKVIQKWLGKGE
                     NIKIINGYGPTEGTCACAAYIIRDRDPNRRELYPIGKPLKNAKLYLVDQQNQEIYDPEI
                     PGELLIGGTQVMAGYWNREQQSKERLVEFKGTTCYKTGDICKYLADGNLFFVGRNDNEV
                     NV"
     CDS_motif       8910..8951
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barD_0001"
                     /evalue="5.50E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="barD"
                     /protein_end="84"
                     /protein_start="70"
                     /score="13.4"
                     /tool="antismash"
                     /translation="LGIFKAGCIHVPLD"
     CDS_motif       9159..9218
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barD_0002"
                     /evalue="8.80E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="barD"
                     /protein_end="173"
                     /protein_start="153"
                     /score="30.5"
                     /tool="antismash"
                     /translation="AYCIYTSGSTGDPKGVLIKH"
     CDS_motif       9747..9824
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barD_0003"
                     /evalue="5.50E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="barD"
                     /protein_end="375"
                     /protein_start="349"
                     /score="28.3"
                     /tool="antismash"
                     /translation="IPGELLIGGTQVMAGYWNREQQSKER"
     CDS_motif       9900..9956
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barD_0004"
                     /evalue="1.10E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="barD"
                     /protein_end="419"
                     /protein_start="400"
                     /score="15.0"
                     /tool="antismash"
                     /translation="FVGRNDNEVNVGGYRVHLN"
     gene            10313..15433
                     /gene="barE"
     CDS             10313..15433
                     /NRPS_PKS="Domain: CAL_domain (64-481). E-value: 4.6e-90.
                     Score: 293.8. Matches aSDomain:
                     nrpspksdomains_barE_CAL_domain.1"
                     /NRPS_PKS="Domain: PCP (600-669). E-value: 9.8e-24. Score:
                     75.2. Matches aSDomain: nrpspksdomains_barE_PCP.1"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (696-1134). E-value:
                     1.1e-161. Score: 530.3. Matches aSDomain:
                     nrpspksdomains_barE_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1251-1548). E-value: 7.2e-115.
                     Score: 375.2. Matches aSDomain:
                     nrpspksdomains_barE_PKS_AT.1"
                     /codon_start=1
                     /function="involved in activation of trichloleucine and
                     condensation with malonyl group"
                     /gene="barE"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     282.4; E-value: 9.6e-86)"
                     /gene_kind="biosynthetic"
                     /note="NRPS/PKS; A, PCP, KS and AT domains are located on
                     BarE"
                     /product="BarE"
                     /protein_id="AAN32979.1"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-89, bitscore:
                     288.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.8e-20, bitscore:
                     61.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.6e-115, bitscore:
                     375.2, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 9.7e-174, bitscore:
                     567.8, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDNPMGIHQKNYDEVNHKLSTSFGGSLNIPSNSPTLLCDLLPRA
                     ALTNKGITYIQADGSEQYQSYQDLLLDAKRILAGLRQWDLKPQDKVILQLEEGHDFIPA
                     FWGCLLGGFIPVPLSIAPTYQQLNNVTKKLHNAWQMLEHPLILTNRELAPEIRSLSTHL
                     NLRDFQTGVIEDLRKQDPTQEIYRGQPDELALLLLTSGSTGLPKGVMLSHRNILSESAG
                     TIQMNHFDSEAVTLNWMPLDHVGGIIMLNVMAVELGCQQVHAPTKYILQNPLHWLALIE
                     RHQATISWGPNFAYSLINDLVQDAEAGSWDLSSISFLVNGGEQISPKVARRFLKLMKRQ
                     GLAETVLRPAFGMSETSGGITWSDQFSLSNTSDDMPFVGLGLPIPGACLRIVNDDNEIV
                     HEGAIGKLQVKGASVTSGYYQNPEINQAAFTADGWFRTGDLGYLENGYLVLTGRDKDVI
                     LINGVNYPAHEIEAVVEEVDGVEISFTAACAIQGKTNSSSSDQLAIFFSAVEANIETNP
                     EVLKGLIKKIRGAVVQNIGINPDYLLPVGKESIPKTAIGKIQRQKLKQQFEAGEFDPLI
                     ETVGQSLRIMGSQETALALPQTEVEQVIVNIWQDVLGLDKIGLQENFFELGGHSLLLLT
                     LQSQLQESFGKELSIAEMFSHPTIEALAQYFTQTQPEDSAAQQGYARAQIRQEVRKADS
                     TEIAVIGMAGRFPGADNLDQFWQNLQNGTESITFFSDSELLASGIDPKLLSNPNYVRAS
                     PILSDVEYFDAHFFGYTNREAEFMDPQQRLLMECAWESLEDAGYDPLTYSGSIGLYAGA
                     MLSTYFIHNLLPNRDTFDEHDDLRVLTPDSMGGLQVVLANDKDYLTTRISHKLNLTGPS
                     VNIQTACSTSLVTVHTAVQSLLNGECDLALAGGVSVQVPQRVGHLHQEGLIASPDGHCR
                     AFDAQAEGTIFGNGVGLVALKRLEEALQDGDHIYAVIKGSAINNDGSNKVAYTAPNGEG
                     QTTVVAEAIATANINPETITYVEAHGTGTLLGDPIELGALSQAFQAKTQRKQFCALGSV
                     KTNVGHLQITSGIVGLIKTVLALYHKQIPPSLHFQTPNPKIDFANSPFFVNTMLSEWER
                     NGHPRRAGVNSLGFGGTNAHVILEEAPENAQPKTRNEDGAKLEDRSHHLLTLSAKTAPA
                     LQALVKRYQRYLSDNTEVELGDICYTACVGRAHFEHRLAIVSDSIPDLRCKLANVLDDN
                     AELSPEQTQELAQGQTKASVRAQIAFLFTGQGSQYLNMGRQLYQTQSVFRDAIDQCDQI
                     LQSELEVSLIDLLYPQTADEQNAARLNNTAYTQPALFAIEYALAQLWQSWGIQPAVVMG
                     HSVGEYVAATIAGVFDLETGLKLIAARGRLMQQLPAGXAMVSVMASEERVRSLISPHTE
                     KISIAAINGPESVVISGVAEVLGAISNQLESAGVKTKSLQVSHAFHSPLMEPILAEFTT
                     VAEQLTYHSPRIPLISNVTGVKADEQIATAQYWVNHIRQPVRFAHSMEALSEFGYDCFL
                     EIGPKPILLGMGRQCLPEGTGVWLPSLRPTVDDEQQMLSSLGKLYVQGVRVNWSSLNQE
                     YSYQKVTLPTYPFERKKYWIEKYETNEQKFTSATSKNQKNNFIRLLNQGNVLDLIQYLK
                     KTLDLSREEEVKLLSKFAQLIINLYHQENELLTNKDRKEKDLMNQMLQMDSENLNKLLS
                     EAEKFSQNS"
     aSDomain        10505..11755
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barE_CAL_domain.1"
                     /evalue="4.60E-90"
                     /label="barE_CAL_domain.1"
                     /locus_tag="barE"
                     /protein_end="481"
                     /protein_start="64"
                     /score="293.8"
                     /tool="antismash"
                     /translation="SYQDLLLDAKRILAGLRQWDLKPQDKVILQLEEGHDFIPAFWGCL
                     LGGFIPVPLSIAPTYQQLNNVTKKLHNAWQMLEHPLILTNRELAPEIRSLSTHLNLRDF
                     QTGVIEDLRKQDPTQEIYRGQPDELALLLLTSGSTGLPKGVMLSHRNILSESAGTIQMN
                     HFDSEAVTLNWMPLDHVGGIIMLNVMAVELGCQQVHAPTKYILQNPLHWLALIERHQAT
                     ISWGPNFAYSLINDLVQDAEAGSWDLSSISFLVNGGEQISPKVARRFLKLMKRQGLAET
                     VLRPAFGMSETSGGITWSDQFSLSNTSDDMPFVGLGLPIPGACLRIVNDDNEIVHEGAI
                     GKLQVKGASVTSGYYQNPEINQAAFTADGWFRTGDLGYLENGYLVLTGRDKDVILINGV
                     NYPAHEIEAVVEEVDGVE"
     aSModule        10505..12319
                     /domains="nrpspksdomains_barE_CAL_domain.1"
                     /domains="nrpspksdomains_barE_PCP.1"
                     /incomplete
                     /locus_tags="barE"
                     /starter_module
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       10892..10951
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barE_0001"
                     /evalue="2.80E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="barE"
                     /protein_end="213"
                     /protein_start="193"
                     /score="22.9"
                     /tool="antismash"
                     /translation="ALLLLTSGSTGLPKGVMLSH"
     CDS_motif       11516..11599
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barE_0002"
                     /evalue="4.30E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="barE"
                     /protein_end="429"
                     /protein_start="401"
                     /score="19.1"
                     /tool="antismash"
                     /translation="GAIGKLQVKGASVTSGYYQNPEINQAAF"
     aSDomain        12113..12319
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barE_PCP.1"
                     /evalue="9.80E-24"
                     /label="barE_PCP.1"
                     /locus_tag="barE"
                     /protein_end="669"
                     /protein_start="600"
                     /score="75.2"
                     /tool="antismash"
                     /translation="EQVIVNIWQDVLGLDKIGLQENFFELGGHSLLLLTLQSQLQESFG
                     KELSIAEMFSHPTIEALAQYFTQT"
     aSDomain        12401..13714
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barE_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="1.10E-161"
                     /label="barE_PKS_KS.1"
                     /locus_tag="barE"
                     /protein_end="1134"
                     /protein_start="696"
                     /score="530.3"
                     /tool="antismash"
                     /translation="IAVIGMAGRFPGADNLDQFWQNLQNGTESITFFSDSELLASGIDP
                     KLLSNPNYVRASPILSDVEYFDAHFFGYTNREAEFMDPQQRLLMECAWESLEDAGYDPL
                     TYSGSIGLYAGAMLSTYFIHNLLPNRDTFDEHDDLRVLTPDSMGGLQVVLANDKDYLTT
                     RISHKLNLTGPSVNIQTACSTSLVTVHTAVQSLLNGECDLALAGGVSVQVPQRVGHLHQ
                     EGLIASPDGHCRAFDAQAEGTIFGNGVGLVALKRLEEALQDGDHIYAVIKGSAINNDGS
                     NKVAYTAPNGEGQTTVVAEAIATANINPETITYVEAHGTGTLLGDPIELGALSQAFQAK
                     TQRKQFCALGSVKTNVGHLQITSGIVGLIKTVLALYHKQIPPSLHFQTPNPKIDFANSP
                     FFVNTMLSEWERNGHPRRAGVNSLGFGGTNAHVILEEAP"
     aSModule        12401..16879
                     /complete
                     /domains="nrpspksdomains_barE_PKS_KS.1"
                     /domains="nrpspksdomains_barE_PKS_AT.1"
                     /domains="nrpspksdomains_barF_oMT.1"
                     /domains="nrpspksdomains_barF_PKS_PP.1"
                     /locus_tags="barE"
                     /locus_tags="barF"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       12917..12961
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barE_0003"
                     /evalue="4.60E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="barE"
                     /protein_end="883"
                     /protein_start="868"
                     /score="15.7"
                     /tool="antismash"
                     /translation="GPSVNIQTACSTSLV"
     CDS_motif       13340..13387
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barE_0004"
                     /evalue="3.20E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="barE"
                     /protein_end="1025"
                     /protein_start="1009"
                     /score="12.9"
                     /tool="antismash"
                     /translation="YVEAHGTGTLLGDPIE"
     aSDomain        14066..14956
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barE_PKS_AT.1"
                     /evalue="7.20E-115"
                     /label="barE_PKS_AT.1"
                     /locus_tag="barE"
                     /protein_end="1548"
                     /protein_start="1251"
                     /score="375.2"
                     /tool="antismash"
                     /translation="LFTGQGSQYLNMGRQLYQTQSVFRDAIDQCDQILQSELEVSLIDL
                     LYPQTADEQNAARLNNTAYTQPALFAIEYALAQLWQSWGIQPAVVMGHSVGEYVAATIA
                     GVFDLETGLKLIAARGRLMQQLPAGXAMVSVMASEERVRSLISPHTEKISIAAINGPES
                     VVISGVAEVLGAISNQLESAGVKTKSLQVSHAFHSPLMEPILAEFTTVAEQLTYHSPRI
                     PLISNVTGVKADEQIATAQYWVNHIRQPVRFAHSMEALSEFGYDCFLEIGPKPILLGMG
                     RQCLPEGTGVWLPSLR"
     CDS_motif       14069..14116
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barE_0005"
                     /evalue="2.40E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="barE"
                     /protein_end="1268"
                     /protein_start="1252"
                     /score="19.9"
                     /tool="antismash"
                     /translation="FTGQGSQYLNMGRQLY"
     CDS_motif       14255..14311
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barE_0006"
                     /evalue="1.50E-05"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="barE"
                     /protein_end="1333"
                     /protein_start="1314"
                     /score="17.9"
                     /tool="antismash"
                     /translation="YTQPALFAIEYALAQLWQS"
     CDS_motif       14315..14437
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barE_0007"
                     /evalue="1.20E-25"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="barE"
                     /protein_end="1375"
                     /protein_start="1334"
                     /score="81.8"
                     /tool="antismash"
                     /translation="GIQPAVVMGHSVGEYVAATIAGVFDLETGLKLIAARGRLMQ"
     CDS_motif       14531..14569
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barE_0008"
                     /evalue="1.10E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="barE"
                     /protein_end="1419"
                     /protein_start="1406"
                     /score="15.3"
                     /tool="antismash"
                     /translation="AAINGPESVVISG"
     CDS_motif       14723..14755
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barE_0009"
                     /evalue="1.60E-03"
                     /label="PKSI-AT-M_m7"
                     /locus_tag="barE"
                     /protein_end="1481"
                     /protein_start="1470"
                     /score="11.1"
                     /tool="antismash"
                     /translation="PRIPLISNVTG"
     CDS_motif       14789..14824
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barE_0010"
                     /evalue="1.40E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="barE"
                     /protein_end="1504"
                     /protein_start="1492"
                     /score="18.3"
                     /tool="antismash"
                     /translation="YWVNHIRQPVRF"
     gene            15476..16990
                     /gene="barF"
     CDS             15476..16990
                     /NRPS_PKS="Domain: oMT (68-323). E-value: 4e-117. Score:
                     383.2. Matches aSDomain: nrpspksdomains_barF_oMT.1"
                     /NRPS_PKS="Domain: PKS_PP (396-468). E-value: 2.3e-14.
                     Score: 45.4. Matches aSDomain:
                     nrpspksdomains_barF_PKS_PP.1"
                     /codon_start=1
                     /function="involved in addition of O methyl group"
                     /gene="barF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /note="contains methyltransferase (MT) and ACP domains"
                     /product="BarF"
                     /protein_id="AAN32980.1"
                     /sec_met_domain="PP-binding (E-value: 6e-15, bitscore:
                     45.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDDLENMNNLQERLSKLSPEQRQFFEKKIAENKPHQQLSGQEFI
                     AEKGSTEERLSRYYRALDHSNTAKDYARFAPFSEVVPDFSWLEVILNPDQHPEQTSLSL
                     QAQAEMKAVLFRGIDFSSIKKVMDIGCGYSHDLIDLATNHVHLQLDGYNISPEQVKAGE
                     QKIQGLGYSDRIYLYNRDSAKQPLPDTYDLIFSCQVIHHIKRKEDVFLNISQHLNDSGF
                     FVAAEIISNLPLTPIDDAKSTAYYVTRSKWAQLLARNNLKVVEGVDASLGIANYLYDPN
                     FTDNLARLCQGYDENAKDHFVGPHELGELLRKKLAVYLLITVQKDSFTEKETILRLNQE
                     KLQNLTPYSKIIENSPNGKPLLLPQFFREGSTTFSQGTREDFRQQFLSQDLSDAQVGLA
                     FYLKTVVAAILKETQAEINEETSLTVMGVDSLMVLELRNRVQADLGVDISVADLMGDIN
                     ISRLAIKVSELLHRNAQGAQDLESKMDGDNLQEIALQDKKMREGRL"
     aSDomain        15680..16444
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barF_oMT.1"
                     /domain_subtype="oMT"
                     /evalue="4.00E-117"
                     /label="barF_oMT.1"
                     /locus_tag="barF"
                     /protein_end="323"
                     /protein_start="68"
                     /score="383.2"
                     /tool="antismash"
                     /translation="KDYARFAPFSEVVPDFSWLEVILNPDQHPEQTSLSLQAQAEMKAV
                     LFRGIDFSSIKKVMDIGCGYSHDLIDLATNHVHLQLDGYNISPEQVKAGEQKIQGLGYS
                     DRIYLYNRDSAKQPLPDTYDLIFSCQVIHHIKRKEDVFLNISQHLNDSGFFVAAEIISN
                     LPLTPIDDAKSTAYYVTRSKWAQLLARNNLKVVEGVDASLGIANYLYDPNFTDNLARLC
                     QGYDENAKDHFVGPHELGELLRKKLAVYLLITV"
     aSDomain        16664..16879
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barF_PKS_PP.1"
                     /evalue="2.30E-14"
                     /label="barF_PKS_PP.1"
                     /locus_tag="barF"
                     /protein_end="468"
                     /protein_start="396"
                     /score="45.4"
                     /tool="antismash"
                     /translation="GLAFYLKTVVAAILKETQAEINEETSLTVMGVDSLMVLELRNRVQ
                     ADLGVDISVADLMGDINISRLAIKVSE"
     gene            16987..25650
                     /gene="barG"
     CDS             16987..25650
                     /NRPS_PKS="Domain: Condensation_LCL (60-354). E-value:
                     2.1e-93. Score: 304.4. Matches aSDomain:
                     nrpspksdomains_barG_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (531-923). E-value:
                     2.8e-114. Score: 373.7. Matches aSDomain:
                     nrpspksdomains_barG_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (1016-1239). E-value: 2e-127. Score:
                     417.0. Matches aSDomain: nrpspksdomains_barG_nMT.1"
                     /NRPS_PKS="Domain: PCP (1446-1512). E-value: 4.2e-27.
                     Score: 86.0. Matches aSDomain: nrpspksdomains_barG_PCP.1"
                     /NRPS_PKS="Domain: Heterocyclization (1540-1838). E-value:
                     2.3e-104. Score: 340.8. Matches aSDomain:
                     nrpspksdomains_barG_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (2014-2412). E-value:
                     6.6e-96. Score: 313.2. Matches aSDomain:
                     nrpspksdomains_barG_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2533-2602). E-value: 1.2e-24.
                     Score: 78.1. Matches aSDomain: nrpspksdomains_barG_PCP.2"
                     /NRPS_PKS="Domain: Thioesterase (2621-2870). E-value:
                     1.9e-40. Score: 131.5. Matches aSDomain:
                     nrpspksdomains_barG_Thioesterase.1"
                     /codon_start=1
                     /function="responsible for the recognition and activation
                     of phenylalanine and cysteine and for the release of the
                     barbamide intermediate from the assembly line"
                     /gene="barG"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 59.5; E-value:
                     5.9e-18)"
                     /gene_kind="biosynthetic"
                     /note="NRPS; two NRPS modules are located on the protein
                     containing C, A, MT, PCP, Cy, A, PCP and Te domains"
                     /product="BarG"
                     /protein_id="AAN32981.1"
                     /sec_met_domain="Condensation (E-value: 1.5e-67, bitscore:
                     217.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-124, bitscore:
                     404.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-17, bitscore:
                     53.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLSEFLQELVISGWQFWAEEGQVCFQAPDADSTDQVLAQLKQHK
                     RDILTILQEHPEVLQVYPLGYGQQGIWFLWQLFPDNPNYNVSFATRIYSQVNVTTWQQT
                     FEALRKRHPLLCSTFPKCGETPIRQHSEQLDFVQIDASTWDENELQTQVVAAHRHPFDL
                     QTDPVMRVRWFTRSEQEHILLLTIHHIAWDGSSANIIVKELSELYQAHCAGVAVDLPSL
                     QHTYQDYVKWQQQLVEGSKGESLWTYWQQQLAGELPVLNLPTDRPHPPIQTNNGAVYRF
                     QLPEHLVTQVKALSQAEGATLYMTLLAAFQVLLHRYTGQEDILVGSPTSGRTRPEFTSV
                     VGYFVDSMVMRAKVSGSLSFREFLTQVRQTVIDALAHQDYPFSLLVEKLQPERDLSRSP
                     IFQVFFGLHNFLQSETQQLFLGETKTLVHWGGMEVETFLFDQYESLEDLVLEIIEINSQ
                     LSGFFKYNTDLFDEQTIAQMASHLQTLLAGIVTHPEQRLESLPLLTQAEQHQLLVEWNQ
                     TTTHYPTDKCIHQLFEEQVEQTPDAIAVVFKEEKLSYQELNIRANQLARYLQSLGVSPE
                     VLVGVCVERSLEMIVGLLGILKAGGVYVPLDPKYPQERLDYMFRDSQMSVLLTQQQLLT
                     LLPQYEAKVVCLDRDWQKIVTENPKNVTSEVTAENLAYVIYTSGSTGKPKGVMVAHIGL
                     HNLLKVQIQAFKVSSNSRVLQFASLSFDASIWEIVMALGSGASLYLESRENLLPGASLS
                     KWLNEKKITHLTLPPSALAVMQKEELPSLQTIVVAGEACPAEVISQWSQGRQFVNAYGP
                     TESTVCATMAECSPEYSVLPIGHPIANTQIYLLDNNLQPVPIGIPAEMYIGGIGLARGY
                     LNRPDLTTQKFIPNPFSNKAEQRLYKTGDLARYLPDGNIEFLGRIDHQVKIRGFRIETA
                     EIEAVLNQNPTVKQTVVVAREDKPGDKHLCAYIVAQMETATNSNPELSETHLNSWQEIF
                     NQQIYSQLSEVTDPLFNTTGYLSNYDKQPIPEAQMRDWAEDIVTQVLANKPNSVWEVGC
                     GTGMLLFKIAPHTRAYYGTDISEVSLKYIQTQIAQQPDKYAHVTLAQKAAEEMADIADN
                     SFDVVLLSSIVQYFPSVEYLLQVISNSIRVVKPGGMIFLGDIRSLPLMRAFHTSVQLHK
                     APPSLSVQQLKQGIYRLMQQETELLVSPELFVALKDTYPEITHVQIRLQRGSEHNELNK
                     YRYSVLLHIQAKPTSVIVAPVENGVGMSMEDIEVYLGQQQPESICFSSLTNGRVATDMA
                     AVELLSQVESKLNVQQLRQQLRQKLVNGIEPEQLHQLSASLGYELELCWSHKTEGCFDA
                     VFVRSSLAPEAMVLTPLTQQSVVGGNWHRYGNNPLASVTGKQLIPQWRKYLEERLPEYM
                     VPSRYVILPQLPLTPNGKVNRKALPAPDNTSSRSTEFVAPETSTEKALAAIWAEVLSIQ
                     QVGIHDNFFESGGHSLLATQVVSRIRQALGKELTLQRLLESPTIAELDSALVQLPRVED
                     SPKQKPDGLLPTIVPAPSQRYQPFPLTEIQQAYWLGRNSHFDLGNITTHGYLELDCENL
                     ALDRLSQAWQQVIDHHDMLRMVILPNGEQQVLEQVYPYQIEVLDLRGQPEQIVSTELET
                     IRYRLSHEMFPAGEWPLFKIRVTRLADQRYRLHWSFDALIADAWSMIIVWQQWLQLYQN
                     PDSFLPKLDLTFRDYVLAELSLKDTPQYRRSQQYWWNRLETLPPAPELPLVKQTATLEQ
                     PEFNCYRAELSAPDWQQLQARAKQASLTPSGVLLAAFADFLAYWSKSPKFTINLTLFNR
                     LPLHPQVNDLVGDFTSLTLLEVNQKNAAPFAQRAQRLQGQLWQDLDHRYVGGVEVQREL
                     RRQRGSYQPMGVVFTSTLALNTSAEKGLPSNEWHAWPFDQLGETVYMVSKTPQVWLDNS
                     VAEQNGALLLIWNVVEDLFPEGFLNDMFTSYYHWLQQLATSDVAWAQTCPQLLPLSQLT
                     QRLQVNETYAPVSEETLHNLFVKQVQQRPEAIALITPQRTLTYHELYTEAQALGQQVQQ
                     LGATPNTLVAVLMEKGWEQIVAVLGILMAGAAYLPIDAALPQERQWSLLEQGEVKLVVT
                     QAALNASLGLPDHLHCLVVASQPQEIIDTPLEANVSSSDLAYVIFTSGSTGTPKGVMID
                     HRGAVNTIQDINQRFDVQPTDRMLAVSALNFDLSVYDIFGLLAAGGTLVMPTPEAAKDP
                     VHWVELMTTHQVTLWNTVPALMQMLVEYLSEHPDQVTEDLRLALLSGDWIPLNLPTQIQ
                     SLWPQGQVVSLGGATEASIWSVYYPITTVEPEWKSIPYGKPLVNQSLHVLNHNLDPCPN
                     WVPGQLYIGGIGLAQGYWRDEQKTNASFILHPQTGERLYKTGDLARYLPDGNSEFLGRE
                     DFQVKISGYRIELGEIEATLLGHATVKETVVAAVGELQSKQLVAYVVFHSESSSDSATE
                     DVHDDMRIDELRHYLQQQLPEYMVPPSYMVLDALPLTANGKVDRKRLPTPELISDHYSP
                     DTYIPPRNHQELQLVKLWEEILEVQPIGVGSHFFDLGGHSLLAVRLMNRIEQDFGRSLP
                     LATLFQAPTIEQLAVILQQEQGVPTLSPLVPIQTQGNQPPIFCVHPAGGTVFCYLELSQ
                     LLGANQPFYGLQSLGQQEGQAPLTTVEEMANVYLAAIREVQPQGPYLLMGWSFGGMVAL
                     QMAHDLLSQGEQVAFLGLLDTYAPAHMPDEQVLSEDVEVLLELFGGPLSLDWEVLRDLP
                     SEQQSALIWEQAHQANLVPPDLGAAQIERLLQLMKLNHKAMRSYSPPDYPDVITLLHAE
                     AGSVAVSSTEVTTDPTLGWQAISPSKVEVHTIPGYHEYMVYQPTVVIVAETIKADIEKG
                     LNTDVETSSK"
     aSDomain        17167..18048
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barG_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.10E-93"
                     /label="barG_Condensation_LCL.1"
                     /locus_tag="barG"
                     /protein_end="354"
                     /protein_start="60"
                     /score="304.4"
                     /tool="antismash"
                     /translation="VYPLGYGQQGIWFLWQLFPDNPNYNVSFATRIYSQVNVTTWQQTF
                     EALRKRHPLLCSTFPKCGETPIRQHSEQLDFVQIDASTWDENELQTQVVAAHRHPFDLQ
                     TDPVMRVRWFTRSEQEHILLLTIHHIAWDGSSANIIVKELSELYQAHCAGVAVDLPSLQ
                     HTYQDYVKWQQQLVEGSKGESLWTYWQQQLAGELPVLNLPTDRPHPPIQTNNGAVYRFQ
                     LPEHLVTQVKALSQAEGATLYMTLLAAFQVLLHRYTGQEDILVGSPTSGRTRPEFTSVV
                     GYFVDSMVMRAKV"
     aSModule        17167..21522
                     /complete
                     /domains="nrpspksdomains_barG_Condensation_LCL.1"
                     /domains="nrpspksdomains_barG_AMP-binding.1"
                     /domains="nrpspksdomains_barG_nMT.1"
                     /domains="nrpspksdomains_barG_PCP.1"
                     /locus_tags="barG"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       17230..17346
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0001"
                     /evalue="4.00E-09"
                     /label="C2_LCL_024-062"
                     /locus_tag="barG"
                     /protein_end="120"
                     /protein_start="81"
                     /score="28.9"
                     /tool="antismash"
                     /translation="PNYNVSFATRIYSQVNVTTWQQTFEALRKRHPLLCSTFP"
     CDS_motif       17545..17610
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0002"
                     /evalue="1.20E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="barG"
                     /protein_end="208"
                     /protein_start="186"
                     /score="27.4"
                     /tool="antismash"
                     /translation="IHHIAWDGSSANIIVKELSELY"
     CDS_motif       17950..18039
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0003"
                     /evalue="2.00E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="barG"
                     /protein_end="351"
                     /protein_start="321"
                     /score="39.4"
                     /tool="antismash"
                     /translation="DILVGSPTSGRTRPEFTSVVGYFVDSMVMR"
     CDS_motif       18088..18207
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0004"
                     /evalue="6.50E-24"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="barG"
                     /protein_end="407"
                     /protein_start="367"
                     /score="76.4"
                     /tool="antismash"
                     /translation="RQTVIDALAHQDYPFSLLVEKLQPERDLSRSPIFQVFFGL"
     aSDomain        18580..19755
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barG_AMP-binding.1"
                     /evalue="2.80E-114"
                     /label="barG_AMP-binding.1"
                     /locus_tag="barG"
                     /protein_end="923"
                     /protein_start="531"
                     /score="373.7"
                     /tool="antismash"
                     /translation="FEEQVEQTPDAIAVVFKEEKLSYQELNIRANQLARYLQSLGVSPE
                     VLVGVCVERSLEMIVGLLGILKAGGVYVPLDPKYPQERLDYMFRDSQMSVLLTQQQLLT
                     LLPQYEAKVVCLDRDWQKIVTENPKNVTSEVTAENLAYVIYTSGSTGKPKGVMVAHIGL
                     HNLLKVQIQAFKVSSNSRVLQFASLSFDASIWEIVMALGSGASLYLESRENLLPGASLS
                     KWLNEKKITHLTLPPSALAVMQKEELPSLQTIVVAGEACPAEVISQWSQGRQFVNAYGP
                     TESTVCATMAECSPEYSVLPIGHPIANTQIYLLDNNLQPVPIGIPAEMYIGGIGLARGY
                     LNRPDLTTQKFIPNPFSNKAEQRLYKTGDLARYLPDGNIEFLGRIDHQVKIR"
     CDS_motif       18766..18807
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0005"
                     /evalue="3.00E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="barG"
                     /protein_end="607"
                     /protein_start="593"
                     /score="17.2"
                     /tool="antismash"
                     /translation="LGILKAGGVYVPLD"
     CDS_motif       19000..19059
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0006"
                     /evalue="1.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="barG"
                     /protein_end="691"
                     /protein_start="671"
                     /score="33.1"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVMVAH"
     CDS_motif       19543..19632
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0007"
                     /evalue="2.10E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="barG"
                     /protein_end="882"
                     /protein_start="852"
                     /score="45.6"
                     /tool="antismash"
                     /translation="PIGIPAEMYIGGIGLARGYLNRPDLTTQKF"
     CDS_motif       19720..19785
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0008"
                     /evalue="2.60E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="barG"
                     /protein_end="933"
                     /protein_start="911"
                     /score="35.5"
                     /tool="antismash"
                     /translation="FLGRIDHQVKIRGFRIETAEIE"
     aSDomain        20035..20703
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barG_nMT.1"
                     /domain_subtype="nMT"
                     /evalue="2.00E-127"
                     /label="barG_nMT.1"
                     /locus_tag="barG"
                     /protein_end="1239"
                     /protein_start="1016"
                     /score="417.0"
                     /tool="antismash"
                     /translation="QPIPEAQMRDWAEDIVTQVLANKPNSVWEVGCGTGMLLFKIAPHT
                     RAYYGTDISEVSLKYIQTQIAQQPDKYAHVTLAQKAAEEMADIADNSFDVVLLSSIVQY
                     FPSVEYLLQVISNSIRVVKPGGMIFLGDIRSLPLMRAFHTSVQLHKAPPSLSVQQLKQG
                     IYRLMQQETELLVSPELFVALKDTYPEITHVQIRLQRGSEHNELNKYRYSVLLHIQAKP
                     T"
     aSDomain        21325..21522
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barG_PCP.1"
                     /evalue="4.20E-27"
                     /label="barG_PCP.1"
                     /locus_tag="barG"
                     /protein_end="1512"
                     /protein_start="1446"
                     /score="86.0"
                     /tool="antismash"
                     /translation="EKALAAIWAEVLSIQQVGIHDNFFESGGHSLLATQVVSRIRQALG
                     KELTLQRLLESPTIAELDSAL"
     CDS_motif       21331..21363
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0009"
                     /evalue="4.30E+00"
                     /label="Cy4"
                     /locus_tag="barG"
                     /protein_end="1459"
                     /protein_start="1448"
                     /score="0.8"
                     /tool="antismash"
                     /translation="ALAAIWAEVLS"
     aSDomain        21607..22500
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barG_Heterocyclization.1"
                     /evalue="2.30E-104"
                     /label="barG_Heterocyclization.1"
                     /locus_tag="barG"
                     /protein_end="1838"
                     /protein_start="1540"
                     /score="340.8"
                     /tool="antismash"
                     /translation="YQPFPLTEIQQAYWLGRNSHFDLGNITTHGYLELDCENLALDRLS
                     QAWQQVIDHHDMLRMVILPNGEQQVLEQVYPYQIEVLDLRGQPEQIVSTELETIRYRLS
                     HEMFPAGEWPLFKIRVTRLADQRYRLHWSFDALIADAWSMIIVWQQWLQLYQNPDSFLP
                     KLDLTFRDYVLAELSLKDTPQYRRSQQYWWNRLETLPPAPELPLVKQTATLEQPEFNCY
                     RAELSAPDWQQLQARAKQASLTPSGVLLAAFADFLAYWSKSPKFTINLTLFNRLPLHPQ
                     VNDLVGDFTSLTLLEVN"
     aSModule        21607..25596
                     /complete
                     /domains="nrpspksdomains_barG_Heterocyclization.1"
                     /domains="nrpspksdomains_barG_AMP-binding.2"
                     /domains="nrpspksdomains_barG_PCP.2"
                     /domains="nrpspksdomains_barG_Thioesterase.1"
                     /final_module
                     /locus_tags="barG"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       21757..21810
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0010"
                     /evalue="2.70E-08"
                     /label="Cy2"
                     /locus_tag="barG"
                     /protein_end="1608"
                     /protein_start="1590"
                     /score="26.0"
                     /tool="antismash"
                     /translation="VIDHHDMLRMVILPNGEQ"
     CDS_motif       21991..22035
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0011"
                     /evalue="1.30E-05"
                     /label="Cy3"
                     /locus_tag="barG"
                     /protein_end="1683"
                     /protein_start="1668"
                     /score="18.3"
                     /tool="antismash"
                     /translation="RLHWSFDALIADAWS"
     CDS_motif       22333..22389
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0012"
                     /evalue="7.30E-08"
                     /label="Cy4"
                     /locus_tag="barG"
                     /protein_end="1801"
                     /protein_start="1782"
                     /score="25.1"
                     /tool="antismash"
                     /translation="LTPSGVLLAAFADFLAYWS"
     CDS_motif       22402..22440
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0013"
                     /evalue="2.90E-04"
                     /label="afterCy4"
                     /locus_tag="barG"
                     /protein_end="1818"
                     /protein_start="1805"
                     /score="13.4"
                     /tool="antismash"
                     /translation="FTINLTLFNRLPL"
     CDS_motif       22441..22497
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0014"
                     /evalue="5.50E-10"
                     /label="Cy5"
                     /locus_tag="barG"
                     /protein_end="1837"
                     /protein_start="1818"
                     /score="31.2"
                     /tool="antismash"
                     /translation="HPQVNDLVGDFTSLTLLEV"
     CDS_motif       22561..22608
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0015"
                     /evalue="7.90E-06"
                     /label="afterCy5"
                     /locus_tag="barG"
                     /protein_end="1874"
                     /protein_start="1858"
                     /score="18.5"
                     /tool="antismash"
                     /translation="DLDHRYVGGVEVQREL"
     CDS_motif       22750..22800
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0016"
                     /evalue="1.10E-04"
                     /label="Cy7"
                     /locus_tag="barG"
                     /protein_end="1938"
                     /protein_start="1921"
                     /score="15.2"
                     /tool="antismash"
                     /translation="VSKTPQVWLDNSVAEQN"
     aSDomain        23029..24222
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barG_AMP-binding.2"
                     /evalue="6.60E-96"
                     /label="barG_AMP-binding.2"
                     /locus_tag="barG"
                     /protein_end="2412"
                     /protein_start="2014"
                     /score="313.2"
                     /tool="antismash"
                     /translation="KQVQQRPEAIALITPQRTLTYHELYTEAQALGQQVQQLGATPNTL
                     VAVLMEKGWEQIVAVLGILMAGAAYLPIDAALPQERQWSLLEQGEVKLVVTQAALNASL
                     GLPDHLHCLVVASQPQEIIDTPLEANVSSSDLAYVIFTSGSTGTPKGVMIDHRGAVNTI
                     QDINQRFDVQPTDRMLAVSALNFDLSVYDIFGLLAAGGTLVMPTPEAAKDPVHWVELMT
                     THQVTLWNTVPALMQMLVEYLSEHPDQVTEDLRLALLSGDWIPLNLPTQIQSLWPQGQV
                     VSLGGATEASIWSVYYPITTVEPEWKSIPYGKPLVNQSLHVLNHNLDPCPNWVPGQLYI
                     GGIGLAQGYWRDEQKTNASFILHPQTGERLYKTGDLARYLPDGNSEFLGREDFQVKIS"
     CDS_motif       23209..23250
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0017"
                     /evalue="5.20E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="barG"
                     /protein_end="2088"
                     /protein_start="2074"
                     /score="13.5"
                     /tool="antismash"
                     /translation="LGILMAGAAYLPID"
     CDS_motif       23437..23496
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0018"
                     /evalue="9.90E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="barG"
                     /protein_end="2170"
                     /protein_start="2150"
                     /score="33.4"
                     /tool="antismash"
                     /translation="AYVIFTSGSTGTPKGVMIDH"
     CDS_motif       24019..24108
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0019"
                     /evalue="2.30E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="barG"
                     /protein_end="2374"
                     /protein_start="2344"
                     /score="35.9"
                     /tool="antismash"
                     /translation="PNWVPGQLYIGGIGLAQGYWRDEQKTNASF"
     CDS_motif       24187..24252
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0020"
                     /evalue="9.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="barG"
                     /protein_end="2422"
                     /protein_start="2400"
                     /score="33.8"
                     /tool="antismash"
                     /translation="FLGREDFQVKISGYRIELGEIE"
     CDS_motif       24331..24363
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0021"
                     /evalue="2.70E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="barG"
                     /protein_end="2459"
                     /protein_start="2448"
                     /score="-1.2"
                     /tool="antismash"
                     /translation="AYVVFHSESSS"
     aSDomain        24586..24792
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barG_PCP.2"
                     /evalue="1.20E-24"
                     /label="barG_PCP.2"
                     /locus_tag="barG"
                     /protein_end="2602"
                     /protein_start="2533"
                     /score="78.1"
                     /tool="antismash"
                     /translation="ELQLVKLWEEILEVQPIGVGSHFFDLGGHSLLAVRLMNRIEQDFG
                     RSLPLATLFQAPTIEQLAVILQQE"
     CDS_motif       24850..24879
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0022"
                     /evalue="6.40E-03"
                     /label="NRPS-beforete1"
                     /locus_tag="barG"
                     /protein_end="2631"
                     /protein_start="2621"
                     /score="9.6"
                     /tool="antismash"
                     /translation="PIFCVHPAGG"
     aSDomain        24850..25596
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_barG_Thioesterase.1"
                     /evalue="1.90E-40"
                     /label="barG_Thioesterase.1"
                     /locus_tag="barG"
                     /protein_end="2870"
                     /protein_start="2621"
                     /score="131.5"
                     /tool="antismash"
                     /translation="PIFCVHPAGGTVFCYLELSQLLGANQPFYGLQSLGQQEGQAPLTT
                     VEEMANVYLAAIREVQPQGPYLLMGWSFGGMVALQMAHDLLSQGEQVAFLGLLDTYAPA
                     HMPDEQVLSEDVEVLLELFGGPLSLDWEVLRDLPSEQQSALIWEQAHQANLVPPDLGAA
                     QIERLLQLMKLNHKAMRSYSPPDYPDVITLLHAEAGSVAVSSTEVTTDPTLGWQAISPS
                     KVEVHTIPGYHEYMVYQPTVVIVAETI"
     CDS_motif       25030..25104
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_barG_0023"
                     /evalue="8.70E-13"
                     /label="NRPS-te1"
                     /locus_tag="barG"
                     /protein_end="2706"
                     /protein_start="2681"
                     /score="40.6"
                     /tool="antismash"
                     /translation="QPQGPYLLMGWSFGGMVALQMAHDL"
     gene            25696..26778
                     /gene="barH"
     CDS             25696..26778
                     /codon_start=1
                     /function="probably involved in decarboxylation"
                     /gene="barH"
                     /note="hydrolase"
                     /product="BarH"
                     /protein_id="AAN32982.1"
                     /transl_table=11
                     /translation="MLKNFDIIDADSHVLEPDDLWEKYLDPQFKDLAPKDNQFEGKSIM
                     YKTPDVVVAEGRRLFEENPDRYKGGYNPQARVELMEKMGSDVTFLYPTIGLFMWAIDTM
                     DSKLADALVRAYNNWLQDFCSHDPQKLRGVGAISQHDPEDMVPELQRIAEFGWRAVFIR
                     PNPVKGKLLSDPAYEPFWSECERLNIAVTIHEGTHSRLPTAGADRFHSRFALHTCSHPL
                     EMMMGLLAMIEGGVLERHPQLRVGLFEAGCGWLPYWLWRMDEKYENLVYEVKDNVKMKP
                     SEYFHRQCFIGVETSEPYIPELIQYIGADKLLFGSDFPHMDHPNFIESVDEALALKERL
                     PEETIHKILHDNPLNYYGLT"
     gene            complement(27013..28806)
                     /gene="barI"
     CDS             complement(27013..28806)
                     /codon_start=1
                     /gene="barI"
                     /note="membrane protein"
                     /product="BarI"
                     /protein_id="AAN32983.1"
                     /transl_table=11
                     /translation="MFYFITTWNFLLIPCYLIGTAVLNVLQADSFKRVSDRIIAAVWLG
                     IVVLSIALLATSLVFPLNSWVGWCTAVSLSLLSLTSQPTRDEIANLCFMLFPNLALGLL
                     TLEFGVAAFTSRQVTWLDTGLYHYGAIRWLSEYGAVPGIALLLQQLGFTSSWFALAAPF
                     NPPIFDAQVSAITNGFAFLLAIVHFLIALAQLFTNKAQLSDWFIVICSLIVLPLLALSS
                     LMSDILVSPSPDIPVIFLTVIIAWAILIIAHHRSSSVTRGKNSSFKNKFNNKFYDEFIP
                     LILAAGAVTIKLTSLPLLFISVIFYTVFSRFCVQRLVIGGVITSLLLSPMCAVNIITSG
                     CPLFPSSFFCLDLPWSWTAEDAEAVAENTRGWGTWFGSPPPNSNPWLWLFWQWFSSSTL
                     NQIATGIILISILLAIYILRTSIIHRLWGLIWVLGLAISGTLFMMLYAPVIRFGLGYLI
                     LLPGLYITIVCHQKIGNLNLLITKKLPVSKLWIIPPIFRITSYLALSLITLVIVLNQKT
                     SYRLIIPPQMMTSDLVKKQVNGINYFSPQDISPEEHELCWSAKLPCAFELEDNIQLRDP
                     NRGIRGGFIKVKSEKGTGNRE"
     gene            complement(28816..30285)
                     /gene="barJ"
     CDS             complement(28816..30285)
                     /codon_start=1
                     /function="likely involved in the oxidative deamination to
                     convert trichloroleucine to trichloro-a-ketoisocaproyl
                     moiety"
                     /gene="barJ"
                     /product="BarJ"
                     /protein_id="AAN32984.1"
                     /transl_table=11
                     /translation="MEHYPVVITGAGPAGLTAAYDLVKQGIKSIVLEKSNKVGGIARTE
                     VYKGYRFDIGGHRFYTKVEAAHQRWQEVLGEDFIKVPRMSRIYYQGKFYDYPLSIFNTL
                     SNLGIITSLVMLLSYFKAKIKAKLRPWHEPETFEEWVSDRFGRRLYRLFFKTYTEKVWG
                     IPCDKIQAEWAAQRIQKLSLKRAIINALFGSQNSKSLIKEFDYPLLGPGMMWEKFQQAV
                     DNQGGQVRLNTVVTSIQRDGNHIKSITALQDEKTISISGDHFISSMPVTALVKKLDPPP
                     PPAVIEAAKSLSYRAFIIVALIIDAKDLFPDQWIYIHSPEVKVGRIQNFKNWSPKMVSD
                     PSKTCLGLEYFCNEGDEIWNLSDPKLLDLATRELASLGLADAKAVEDGTVLRQPKAYPV
                     YDRDYRQHLQVIQDFLADFDNLQTIGRNGMHRYNNQDHSMLTGMLAVKNLLGENHDLWQ
                     VNTERSYYEEFTTEELKQKQDSVEDSVFQPV"
     gene            complement(30616..31677)
                     /gene="barK"
     CDS             complement(30616..31677)
                     /codon_start=1
                     /gene="barK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 55.4; E-value: 1.1e-16)"
                     /gene_kind="biosynthetic-additional"
                     /note="glycosyltransferase"
                     /product="BarK"
                     /protein_id="AAN32985.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 9e-31, bitscore:
                     96.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDSAKLTISVIIPVYNGGEDFRQCLARLSQAAPPPDQVIVVADG
                     DTDGSWRLAQDFGATVIRLPTAGGPAKARNLGAKVAQTDILFFIDADVAIYPDTIGQVV
                     KIFNNEPNLTALIGSYDDSPGAANFLSQYKNLLHHYTHQTASEEAFTFWGACGAIRRDI
                     FIAMGGFEENYRQPCIEDIELGYRLKQEGYRIKLCKTLRVKHLKPWGIISLLRADFFYR
                     ALPWTAVILKVRDASPENCREFISDLNLKLSSRISVVLVYALLGALVTAYWWSSTLIAM
                     ATCVFSLALLVLNRPVYQFFYQKRGLLFTIRTIPWHWLYYFYSGLAFAIGIVRHCFQKY
                     LQPRIYLPKLSSL"
ORIGIN
        1 ttggggaaat aatgcctcta attctgcacg agtgcgttcg tgtacgacta accaagtagg
       61 aattcctcgt tggcgcaaaa ttcgatagta atgtaatgga agagctgctt caccaccaaa
      121 ctttgcagat gcatgttccg ctgcaatcaa tactcgaagg ttcatattat ataccctatg
      181 ttctgtgatc tgtttatcca ctagcacccg ggattgacct ttggtcacgc tacgccatgc
      241 gacctaggag ccgctaaaac cgatcgacta cacttacttt gtcactctaa ttacctatac
      301 agggtcaatg tatattgtca ataaactact aatatttctt aataaactcg gccttattgt
      361 gcttgttgac aatgtatttt ccacatatag cagtcttaaa tgattcgtga aatatattgg
      421 ccacgctgcg cgaacgccaa atccctataa cccttgccca gcaacgatta ccgattttgc
      481 tgattttaca aatgatttgg gtgcggctct tctagaaata cggtattatt taaaataaga
      541 aaactaacaa gcttgtcaga gtaaggcttt gagtcaaaaa aaccgttaag ggacgtttct
      601 tgtacataag tggaaaaccg gggttaaatt cagagatatg caagcatcgt actcaaatga
      661 agacatcttc ttttcaccag cacgagagct atttgaagaa atcgtagagt ggttgggttc
      721 agatcgggtt tgcggtgcgc gagcatgggg agttagagaa caaattactg gagaacgggt
      781 acgaactatt aagacggcaa ctgccgcggt tattttgata gacgtagtga tgacgagatt
      841 gaaggtgagt gtttgggtag tgaccaagcc agaagaactc ataagaagaa gttgactcgt
      901 aaactgacca ccttatttgg aaccgtaaga gtcaatcgaa ttggttatgg aggaaggaag
      961 ctcaattccc tgagtccatt ggatgcggaa ttaaacctac cgccatccca atattcccac
     1021 ggactgacag agcgagtcgc agtagaagta gcccgttcgg ggtttggtga aacagtagag
     1081 ataaatttcc caaacaaccg cagccaaagt tggtaagcgt caagtggaag aattagcctt
     1141 caatagtgcc tgtgactttg accaatttta ccaccagcaa caatcacata tagagcaatc
     1201 tccacaaaca ggggaaatag tagtgattac tgttgagggt cttggtgtag tgatgctaaa
     1261 ggaagattta cgtgctcata aaagaattag ggcgctggca aagagcaaga agttaaataa
     1321 acgattaacc cttggtgaaa aacgaaactc gaagcgaatg gctacagtag cttcggttta
     1381 taccattgac ccattcgttc gcacacctga acaaattgtc aatccggaag gggaggagct
     1441 tgatattaaa gaactcaaaa gacccaagcc tcaatccaag cgtgtttggg caagcttaat
     1501 taaacagcca gaagtagtta ttagcgaagc atttgacgag gtattgcacc gccgaagcac
     1561 tcaacaaaaa cactttttgt gctttggtag atggtaataa aactcaatta tcgcgctttg
     1621 aagaagtttg cgagcaaaca ccagattaac ttaacaattg ttctcgatat tatccatgta
     1681 attgaatatt tatggaaggc ggcatttgcc ttgaacctat cccactattg tccgaaaact
     1741 tgatagactg aaaatcaagt aatcagaaaa acttgaacag ataaatgcca ggaagatttg
     1801 aaggattaag tgacatagaa tgggagctgt ttgaaaagat tttgccgtgt gaagcgcaaa
     1861 agcgaggtag aggtatgccc catgtaccat tccgttacgt tttaaacaca ctgctgtacg
     1921 tattaattac aggatgtcgt tggtgtgatg tgcccagagg ggaacagtgg gcatcaaaaa
     1981 gttcagcaca tcgatggttg aaacgatggc aaaaaaacgg aacttagcga aaaaatacaa
     2041 tgtagagtat tggcgatcgc gcaaaatcga gggttgatta actggaatta tggagccgta
     2101 gatggctctt tttccccctg gcaagggagg aggtgaagga gtagcctatg gatataaagg
     2161 gaaaggagtg ttgatacaca cagtcacaga aggtaatggt atgcccatgg cttacagcac
     2221 cacaccagct aatgggagtg aaccggagca ggtgatacca ttactagata gcatcgcgct
     2281 ttgttacagg taaacggggt cgtcccttga aaagattccg agtaatagcc gctgacaagg
     2341 gttacgactc attagagaaa cgttcactgc taagaattag aggtaaatga ccccagttcc
     2401 ctaaaagagt tgatcagtcc ttgatgcatc gaggtagacc aatcaaagat gatacaccac
     2461 gatttcaact ttaacgaaga ttcacttggt atcaaaggaa gtaccgacgg aaaggtggtt
     2521 cgttgggaac gcggcttgtg ttgtgttcga tgctttcctt gccaagcgcg actattcata
     2581 agctgttcgg catttaaatt ggtatagttg tttcaattaa ggataagacg gtgatgaggt
     2641 aaaatgaaaa gggtatattt tcaataactg acagcaatgc catacagtct agatttcaga
     2701 aaaaaagtaa taaactatat agaaaaaggt ggaaaaatta cagaggcagc gaaagtattt
     2761 gggataggaa gagcgacaat atacaagtgg ttgaatcgtt ccgaactaaa ggctaataaa
     2821 gtagaacgtc gtcaaagaaa gctagattgg aaagccttat aacaagatgt caaagaaaat
     2881 ccagatgcta aattaataga gagagccaaa aaatttggag tgcgcccaag tgcaatatta
     2941 tacgcactca aaaaaatgaa aataactcgt aaaaaaaaag aacttcgtta tcgggaaaga
     3001 gataggaaag aaagaataaa gtatttaaga gcattaagag aattaataaa aatatctgga
     3061 attaaaagcc ttgtattcat tgatgagtcg gggtttgaca aaatacagtc atgcctttat
     3121 ggatggtcaa aaaaagggaa aaaactgtat ggtgaacaaa caggaaaacg aataaaaaga
     3181 gaaaatttag tagcaggaag aaggaagaaa tcaaaagatt taatagcccc ttgtttagtg
     3241 gtagtcttaa tgcagaagta tttgaaggat ggttaagcca atatttatta gcctcattaa
     3301 caattccttc agtattaatt atggataatg caccaattca tagaaaaaat gcaattagag
     3361 aattagtaga gtcagccggt catcaagtat tatttttgcc gaaatactct ccagatttca
     3421 atgatataga gcatgatttt agtgctttaa agagagccag aatgtatact tctatagaca
     3481 cttctctgga tgaagtaatt cgtgaatatt gtgcttctta gtgtctcctc cttatttaaa
     3541 ataactatat aataaaaatt aataaataac ccaanaatan naaatatgcc agcaaaaaat
     3601 tatctgacag caaaaaacaa tacttcaaaa agccttaaaa atagaagaaa atggaaatat
     3661 tagagaacgt attttaattt tgctgttgtt gaatagtgga aaaacacagt tagaaattgc
     3721 tgaagttttg ggttgttcaa agaacacagt ctgttattgg tgtgtccacg gagatccaga
     3781 tgacttagag agtcttaaag ataaaagaat gaaaggcaat caccaaaaag caacaaaaca
     3841 atatatagaa gtattattag aattagtcga aaaagaaccc gaagaattag gatatgaatt
     3901 tggtcgatgg acagctcaaa aattagccgt tcatttagaa gatacaacag gcatcaagtt
     3961 aagtgggtct caagttcgta ggatactagt caagaaaaaa tatgtttacc tttggtcaaa
     4021 gtatagctta gattctaaaa aagaccctaa aaaaagggaa gcatttaaaa agaaactaga
     4081 tgagtattta aaaatagaaa aagaaagccc agagcgtctt caggtatggt tttgggatga
     4141 aagcggattt agtttgagag tcatcagaag aaaaaactgg tgtaaaagag gaaagcgaaa
     4201 aaaagttaga ggagaccgtt cgcgcagcgt cgggctttgc ccgaaaggca agggagagtt
     4261 aatgtgatgg gagctttgcg atattcagat aaaaaaagat ttgtagattt cctcaaaaaa
     4321 agcaatagtc aaacttttta tgaagtttta aaaacctttt ataaagagct agaaaatgaa
     4381 tggatggaag cgggtaatca actagaagac tttgctaaga aaggaccgaa aatcgtcatt
     4441 attttagaca atgctagttt tcacaaaaaa gccgaatata ttcataaaat agaagaagat
     4501 atgccgaata tttatttaga atatcttccc gagtatagtc ctgattataa cttaattgaa
     4561 ttggtttggc attcagcaaa agaatatatt gccaatcgag ttttcaaatc aattgaagaa
     4621 ttagaatgtt tgttaaatca tcttttaaat gaaggagggt taattataaa atgggtacga
     4681 aaaataaaaa acaaaggcaa tgctgttatc acagtttaaa tgcgcaacag cttatgtgga
     4741 ttactaaaat tatattagtg ggataggttc attacagcga gtttacgaat cagctctgag
     4801 gtgcttttga ataaaataac cacctcaagc agcgtgagcc ttggccttgg ccataggcca
     4861 agctttcggc aaagccgacg cttcgcgaac gcgaatggct gacggctgaa tgcttacata
     4921 tttagtttat attttttagg ttaattattt attattaaca aagcttaata actattattt
     4981 tttcgttgaa agttgtcatt tttgtgaatg atcgcaagca tctcaaagct agtgatagaa
     5041 ctgctttgca attcctggag atgtctacag ggtaattcta gatttttggt attattgttt
     5101 actttttgaa tgtaaatttt gatacaaatt tagatgcgtt taccttgaat aaccctcgac
     5161 gttttttttt cggtgctttc ataatgtttt tctatactat taaaaatatt cataatattt
     5221 tttgataaga taatcttgtt atttttggct ggctctgtga taccatgaaa aatggatata
     5281 gcaattctca tattcatgag gacaaagctt atcattttca ggcaagatgc aaaaggcaaa
     5341 agccaatatt taagggggtt gtacggggat aatcctgaaa ttgcgctgta catcataatc
     5401 acgataaacg ctataaataa gcaaagtgta taaactcccc ttaacactct tccttactta
     5461 aaaaggttag tccagagatg tgacaagcac ttttaacatc tcttatagat agataaatca
     5521 ggataaatag atgagtaatt caacagaact acccatttct gatgtcgtgg ttccccagac
     5581 agaaacagaa aagcagcttg ctgaaatatg gaaagacgtt ctcagtgttg agacaatcag
     5641 tatagaagat cgctttatgg atatcggggg gaactcaata aatttggttg aagtggttaa
     5701 tcaggtaaca gaaaagatgg gggttagcat caaagctcgg tggttttttg ataagcacaa
     5761 atcaacaatt gctgaactga gtaaagaaat tgatgcggtc agagagcaaa cacattagca
     5821 gttaacttta tcggtgagta aaaaagtaga tgaaaactag ggcaaaagct gaactcagtt
     5881 attatctttc tgtggaagaa aaacaattct ttcgagacaa tggctatatt ggacctttta
     5941 ctctatttca acctgaagag atcctggagt tgtggaacga aatcaggatg gatcttttgg
     6001 acagggaaac ggcacctttc cctaacagta aaatgaacta tgaccgtcat ctggatatcc
     6061 aggctttgag tgatattatc tctcacccaa aaattgctca ccgtgttagc agtcttttgg
     6121 gctcaaatgt actatgttgg agaacggctt ggtttcccaa atatcctggt gatgaaggaa
     6181 cagactggca tcaagcagaa agcttcgtcg agtttgaggg caagtcaaag ctggttccta
     6241 ctgagtctca cgatggacct tgggaactga ctgcttgggt tgcatttagt gaagccaccc
     6301 gagaaaatgg ctgtatgaaa gtaatgcccg gtactcacaa tacctggtac tttgacgagc
     6361 atcgtaacat tgagtttgag ccagacaaga tcaaccaaaa actcactggg ggtaaaaaga
     6421 ctggggtcta tggctatgac tactataaac tgaaactaga tcctaactgg gagcctgatg
     6481 aatcccaagc ggtacacctg gaaatggaac cgggtcaatt tattctgttt acgtctagat
     6541 gtatgcatgg ctcagaacca aatacctctg gctcatcgat acgttacggc tggtcaacac
     6601 gcttcgttcc cacagacgtg agagtatatc cagattggga atcttttcag cactttggag
     6661 aagtatttcc tttagaacgg tatgcaactg ttctggtagc aggggaagat acttacaaac
     6721 acaacaaaat tagacgacct ttgggacagt aacctgagta gatttgttgc agaagtattt
     6781 gaccacttca agagaaacaa gggagataag aatgaaaact atcactgctg aacccagata
     6841 ctatctttct gtggaagaaa aacaattctt tcaggaaaat ggctatattg gaccttttac
     6901 tctcttccca ccagaagaga tgcttgagtt atggtatggt atcaagatgg atctgttgga
     6961 caaggaaacg gctcctttcc caaacaacaa aatgaactat gatcgccatc ttgatatcaa
     7021 ggctctcaat gatatcatct ctcacccaaa agttgttgat cgtgttagta gtattttggg
     7081 tccaaatgta ctgtgctggc gaacagagtg gtttcccaaa tatccgggtg atgaaggtac
     7141 agactggcat caagcagaaa gcttcgtaga atttgaggga gagtcgaagc tggttcctac
     7201 tgagtctcac gatggacctt gggaactgac tgcttgggta accttcagtg aagccactcg
     7261 aaaaaatggt tgtatgaaag tcatgcctgg tactcacact acctggtact ttgacgaaca
     7321 tcggaacatt aagtttgagc cagataatat caaccaaaaa ctcaccaaag gccaaaaatc
     7381 aggtttctat ggctatgact acgataaact gaaactcgat ccaaattggg aaccagatga
     7441 atcccaagcg gtacacttgg agatggaacc gggtcaattt ttcctgttta cctctcgctg
     7501 tatgcatggt tctgaaccaa atacctctga atcatcgata cgttacggtt ggtcaacacg
     7561 ctttgtatca acagatgtga gagtatatcc agattgggat tcttttgagc actttgggga
     7621 aaagtttatg ctggatcgct attcaactgt tctagtggct ggggaagata cttacaaaca
     7681 caacaaagtg agacaacctc tgtagagaat ttgtcaagta ttctcggcaa accgggtttc
     7741 ccatgaggag gacaaggaaa tatcagtatt tcctcaaaag aaccccggtt tcttgactgg
     7801 ctctctaaga aaggaacctc ctagcatacc ttcatggcaa catattagtt ataagccaat
     7861 gcaaacagat gattcatcct ggttaatttt tgatgaaacc ccaaaatgtg aggcatccaa
     7921 gatgcgttta ttttgctttc attatgcagg tgcagggggt tctattttcc aggattggtc
     7981 gagagcgctc cctgatgaag ttgagttagt cgcaattcag ttaccaggca gggaaaagcg
     8041 ttgttatgaa ccgttaatgt ccaatattga ggacattaat cttgtactag ctcaagagtt
     8101 gtcgccgttt ctgtccaaac cctttgcttt tatgggtcat agcatgggtg cattgattgc
     8161 tttcgacttg attaggctat tacgtcaaca agaactcgga caaccccaat ttctaatggt
     8221 ttcagggttt gatgctcccc agctaagacc aaaagaatcc tcaaatatgc accagttgcc
     8281 tgatgatgaa tttgctcaag caattcgcga ttataacggg atacctcaag tgattgctca
     8341 aaatgaggaa ttgtttgagt tgctgcttcc acgcctccga tcggacatca aactgggaga
     8401 aacttatatt tataaagatg aagagccact ggactgccgg atcattgctt tatatagtac
     8461 agaagattca tttgttagta agagcggtat gtatagttgg caagaacaaa ctaaggggga
     8521 gtttgaacta tatactttcc ctggagacca tttcttcctg cacagtgcag aagagttagt
     8581 gcttaacact atctgcacag aattacagcg atatattaag gctaatgata attgttcgac
     8641 gaaagtagca ttgcaaaaat catagcttac taaccatcat ataaaaggat gaaatcacca
     8701 tgggtaaaaa cattgctaat cttgtgacaa gacatagtaa aaaatctcct cataaatgtg
     8761 caataacaga tggacaaact gaattatcct atggtgtctg ggaggcagct agtaaccgct
     8821 ttgcacgaaa gttaatcgag atgggttgtc aaaaaggcga tcgcgtagtg gtactagcca
     8881 gtaagcagac tatactcatg gttggtatac tgggcatatt taaggcaggc tgcatccatg
     8941 tgcccctaga tggtaagatg cctgtcaatc gtcttaataa aatcattaca gaaattattc
     9001 ctagtgtgat attgacagac caagaattat tgcatttggt cagcgaaaat gttccgcagg
     9061 aagtgaaaat agttctaatc gagcaattac accctctaat caccgacagc acagtagagg
     9121 aaaaagatag attgccacaa attgaaagtg aagatattgc ttattgcatt tatacatcgg
     9181 gctcaactgg agatcctaaa ggagtattga ttaagcatgg cagtgtcata gatttttttg
     9241 agggaactcg agagttttat gatgtagatg aagattcacg ttgtgtcagt ttctcacctt
     9301 ttcattttga tgcatcagta atagatatac tatttcccct ttaccaagga gcctggctat
     9361 atttatatag tgatgttgtc ttacatgagt tgctgtttga ggtaatcaaa aataactcag
     9421 taactcattt tgctgctttc ggttcaatgt taggcttgat tgcgcaaaca aaagagttcg
     9481 acgatgttat ccttaaagat ctcaaaacaa ttctaactgg tgcagatgtt cccgatatca
     9541 aagtgatcca aaaatggttg ggaaagggtg agaacataaa aattatcaat ggctacggac
     9601 cgactgaggg aacttgtgct tgtgcagcct atatcatccg cgatcgagat ccaaatcgtc
     9661 gcgagctata tcctattggc aaaccgttga aaaatgctaa gctatatcta gtagatcagc
     9721 agaatcagga gatctacgat ccagaaatac caggagaact cttgatcggt ggcactcagg
     9781 tcatggcggg ctattggaac cgggagcagc aaagtaaaga aagacttgtt gaattcaagg
     9841 ggacaacttg ctacaaaaca ggcgatattt gtaagtacct agcagatggt aacctcttct
     9901 tcgtcggacg gaatgataat gaagtaaatg ttggtgggta tagagttcac ctcaacggaa
     9961 taaagcaagt cattaataga ttccattggg tggaaaattc agaggtagtg acgctagaat
    10021 ctaagtatgg agaaaaaatg ttggctgcgg ctctgatgtt ggcaaatgag acatcaaaag
    10081 atagtgcatt gaaacaaata aaagagcatt taaaccaaga attaccacag tatatggtgc
    10141 cgaggcagat tgtcgttatg gaaaaatttc ctcagctatc ctctggaaaa accgatcgaa
    10201 aaacactatc gtctatctta gagagggatt tgctggcaag taaagtgcat taatatattt
    10261 atgatcatcg aggtagaatt gtaattgatt gctgaaaagt ggcactaaac gcatgaagga
    10321 taatcctatg ggtatacatc aaaaaaacta tgatgaggta aatcataaac tttccaccag
    10381 ctttggtggt tcattaaata tcccatcaaa ttctccaaca cttctatgcg atctgttacc
    10441 gcgagcagct ttaacgaata aaggaattac atatattcag gcggatggct cagaacaata
    10501 ccaatcctat caagacttac tattagatgc caaaaggata ttggcagggt taagacaatg
    10561 ggatcttaaa ccacaagata aggtgatatt gcaattggaa gaaggacatg attttattcc
    10621 agccttttgg ggttgtctat taggtggatt tattcctgta cctctatcta tcgcccctac
    10681 ttaccagcaa ttaaataatg taactaaaaa gttacacaat gcatggcaga tgctagagca
    10741 tccgctgata ttaaccaacc gagagcttgc tcctgagatt cggtctctat caactcatct
    10801 aaatttgagg gattttcaga caggtgtcat tgaagatcta aggaagcaag atccaactca
    10861 agaaatttac cgagggcaac cagatgaatt ggctttgctt ttgttaacct ctggcagtac
    10921 tggactccca aaaggagtca tgttgagcca tagaaatatt ttgagtgagt ctgcaggcac
    10981 gatccagatg aatcacttcg attctgaggc ggtaaccttg aattggatgc ccctagatca
    11041 cgtggggggg attattatgc tgaacgttat ggccgtagaa ctaggctgcc aacaagttca
    11101 tgcaccaact aaatatattt tgcaaaaccc actccattgg ttagctttga ttgaacgaca
    11161 tcaagcaaca atctcttggg gaccaaactt tgcatattcc ctcattaatg acttggttca
    11221 agatgctgaa gcagggtcat gggatttgtc atcgatcagt ttcttagtga atggaggaga
    11281 acaaatttcg cctaaagtcg ctcgtagatt tttgaaatta atgaagcgac aaggattagc
    11341 agaaacggta ttacgtccag cttttggcat gtcagaaacc tctggaggca ttacttggtc
    11401 cgatcaattt tcactcagta atacttcaga tgacatgccc tttgttggtt tgggtcttcc
    11461 tattcctggt gcttgtctgc gaattgttaa tgatgataat gaaattgttc atgaaggtgc
    11521 gatcggtaag ctccaagtta aaggggcatc agtcactagt ggttactatc aaaaccctga
    11581 gataaatcaa gctgcattta ctgcggatgg ctggtttagg acgggggatt taggctatct
    11641 agagaatgga tatcttgttt taacagggcg agataaggac gtaattttga tcaatggagt
    11701 taattaccct gcccatgaaa ttgaagcagt agtggaagaa gtggatggag ttgaaatttc
    11761 cttcacagct gcctgcgcta tacaaggtaa aacgaattcg tcttcatcag atcaacttgc
    11821 gattttcttt agtgcggttg aagcaaatat tgagaccaat ccagaagttc tcaaaggact
    11881 aataaaaaaa attagaggtg ctgtcgttca aaatatagga attaatcccg attatctcct
    11941 accggttggt aaggaatcta ttcctaaaac agcaattgga aaaattcaac gtcaaaagtt
    12001 aaagcagcaa tttgaagcag gagaatttga tcctttaatc gagacagtag gacagtctct
    12061 aagaattatg ggatctcagg aaacagcctt agccttacct caaactgagg tagaacaggt
    12121 aattgtcaat atttggcaag atgtcctcgg tttagataaa attggcttgc aagagaactt
    12181 ctttgaatta ggtggtcatt cccttttact gttaacgcta caaagtcagt tgcaagaatc
    12241 ttttggcaaa gaattgtcaa ttgcagagat gtttagtcat cccactatcg aggcgttggc
    12301 tcaatatttc acccagacgc aacctgaaga ttcagcagcc caacaggggt atgcacgggc
    12361 acagattcgc caagaagttc gtaaagcgga ctcaacagag attgcggtga ttggcatggc
    12421 aggtcgattc cctggcgcag ataatctcga tcaattctgg cagaacttac agaatggaac
    12481 ggagtccatt acctttttct cagattcaga actattagct tctggcattg atccgaagct
    12541 tttaagtaat cctaattatg tgagagcaag tccaattctt tctgatgtgg aatattttga
    12601 tgctcacttc tttggctata ctaaccgaga agctgaattt atggatcccc agcaacgatt
    12661 attgatggaa tgtgcctggg aaagcttgga agatgcaggg tatgatcctc tgacttattc
    12721 aggctctatt ggtttgtatg cgggagcaat gttaagtact tatttcattc ataatcttct
    12781 gcccaaccgt gacacttttg atgaacatga tgatttacga gtactcactc ccgactctat
    12841 gggcggcctg caggtggtac ttgctaatga taaagattat ctgacaacac gcatctccca
    12901 taaattgaac ctgactggac cgagtgtcaa tattcaaacg gcttgctcaa cttcactcgt
    12961 tacagttcac acagcagtcc agagcttgct taatggagaa tgtgacttgg ctcttgcggg
    13021 aggtgtttca gtgcaggtgc cccaacgagt tggacatctc caccaagaag ggctcatagc
    13081 atctcccgat ggccactgtc gagcctttga tgcccaagca gaaggaacta tttttggcaa
    13141 tggcgttggc ttggttgcct tgaagcgcct ggaggaagct ctccaagatg gagatcatat
    13201 ctatgcggtt attaagggat ctgccattaa taacgatggg agcaacaaag ttgcgtatac
    13261 cgcacccaat ggggagggac agactacagt ggtggccgag gcaattgcaa ctgccaatat
    13321 caatcccgag acgattacct atgtggaagc tcacggcaca ggaactttgc tcggagaccc
    13381 gatcgaattg ggtgctctga gccaagcatt tcaggctaaa actcagcgca aacagttttg
    13441 tgcccttggg tctgtcaaaa ccaatgtggg gcacttacaa atcacctccg gcattgtggg
    13501 cttgattaag acagtccttg ctctttacca caaacaaatc ccccctagtc ttcatttcca
    13561 aacaccgaat cccaaaattg actttgccaa tagtccgttt tttgtgaata caatgctctc
    13621 tgagtgggag aggaatggtc atcctcgacg ggccggtgtt aactccttag ggtttggagg
    13681 aacaaatgcc catgtgattt tggaggaagc accagaaaat gcccaaccaa aaaccagaaa
    13741 cgaagatgga gccaagcttg aggaccgatc gcatcatctt ctcacccttt cagccaaaac
    13801 agctcctgca ctgcaagcgt tagtcaagcg ctatcaacgc tatctgagtg acaatactga
    13861 agtggagctt ggagatattt gttatacggc ttgtgtggga agagcacact ttgaacatcg
    13921 gttagcgata gtaagtgatt cgattcctga tctacgttgc aaactggcaa atgtgttgga
    13981 tgataatgct gagttgagcc ctgagcaaac tcaggaactt gctcaagggc agactaaagc
    14041 atcagttcga gcccaaattg ctttcttgtt cactggtcaa gggtcgcaat atctgaacat
    14101 ggggcggcaa ctgtatcaaa ctcagtctgt gtttcgggat gcgattgacc aatgtgacca
    14161 gattttacag tccgagcttg aggtttcttt gattgatctt ctatatccgc aaacagcgga
    14221 tgagcagaat gctgctcggc tgaataacac agcctatacc caaccggctt tgtttgcgat
    14281 cgaatatgcc ttagctcaat tgtggcaatc ctgggggatt cagccagcgg tggtaatggg
    14341 gcatagcgta ggtgagtatg tggcagcgac gattgctggg gtctttgatt tagaaaccgg
    14401 actaaaactg attgctgctc ggggccggtt gatgcagcag ctacctgccg gangagcgat
    14461 ggtatcagtg atggcctctg angagagagt gcgatcgcta atttcccccc ataccgagaa
    14521 gatatctatt gcagctatta atggacctga aagtgtggtg atctcaggtg ttgctgaggt
    14581 cttgggtgcg atctctaacc agcttgaatc agcaggggta aagaccaagt cactccaagt
    14641 ttcccatgca tttcattctc ctctgatgga gccaatattg gcagagttta ccacggtagc
    14701 tgaacaactc acttatcatt ctcctcgcat tcccttgatc tcaaatgtga cgggggtaaa
    14761 agcagacgaa caaatcgcca ctgctcagta ctgggtcaat cacattcgtc aaccagttcg
    14821 atttgcccac agtatggaag cattatctga atttgggtat gactgctttc tagaaattgg
    14881 tcccaaaccc attttgttgg gtatgggacg tcaatgcctc ccagaaggga cgggggtgtg
    14941 gttaccttct ctgcgtccga cggtagacga tgagcagcag atgctctcta gtttaggaaa
    15001 gctatatgta cagggtgttc gggttaattg gtctagtttg aaccaagaat atagctatca
    15061 gaaggtgaca ttacccacat atccatttga acgcaaaaaa tactggattg aaaaatatga
    15121 aacgaatgag caaaaattca catcagcgac ttctaaaaat cagaaaaata attttattag
    15181 attgctcaat caaggaaatg ttttagattt aattcaatat ttaaaaaaaa cattggattt
    15241 atcgcgagag gaagaagtga aattactgtc gaaatttgcg cagttaatta taaatcttta
    15301 tcatcaagag aatgaactct tgactaataa agatcgtaaa gagaaggatt taatgaatca
    15361 gatgctacag atggatagtg aaaatttaaa taagctcttg tcagaagcag aaaaattttc
    15421 gcaaaattca tagcaaaatt aaccaaaaaa ctgaattaat taggaaacaa tcaaaatgtc
    15481 tgacgatcta gaaaacatga ataatcttca agaacgattg tcaaaacttt ctcctgaaca
    15541 acgtcaattt tttgaaaaga agattgccga aaacaaacca catcagcaac tatcaggtca
    15601 ggaattcatt gctgaaaaag ggtcaactga agaaaggtta agccgctatt atcgagcgct
    15661 agatcatagc aataccgcga aagattatgc gagatttgca cccttttctg aggttgtgcc
    15721 tgacttttct tggctggaag ttatcctcaa tcccgatcag cacccggagc agactagctt
    15781 aagtctacaa gcgcaagccg aaatgaaggc tgtattattt aggggcatcg acttctcatc
    15841 gattaaaaaa gttatggata ttggttgtgg atactcccat gatttaattg atttggcaac
    15901 caaccatgtc catctccagc tagatggcta taacatttct ccagagcaag tcaaagcagg
    15961 tgagcaaaaa atccaaggtt tgggctattc tgaccgtatt tacctttaca accgtgatag
    16021 tgctaaacag ccattgcctg atacctatga cttaatcttc agctgtcagg tcattcatca
    16081 tatcaagcgc aaggaagatg tattcttaaa tataagtcaa catctcaacg atagcggttt
    16141 tttcgtagca gcggaaatta tttccaattt gcccttgacg cccattgacg atgccaaatc
    16201 gactgcttat tatgttaccc gatcaaaatg ggcacagttg ctggctcgaa ataatttaaa
    16261 agtggttgag ggagtagatg ctagccttgg aattgccaat tatctgtacg atccaaattt
    16321 taccgataac ttagctcgtc tatgtcaagg ttatgatgag aacgctaaag atcattttgt
    16381 tggtccccat gaacttggag agttactgcg caaaaaattg gctgtttatc tattaattac
    16441 agtccagaaa gatagcttta ctgaaaagga gacaatttta cgactaaatc aagaaaaact
    16501 tcagaactta accccctact cgaaaattat tgagaacagt cctaatggta aacccctgtt
    16561 gttacctcag tttttcagag aaggatcgac gactttttct cagggtacta gagaagattt
    16621 tcggcaacaa tttctgtcac aggatctatc cgatgctcag gttggcttag cgttttatct
    16681 caaaactgtt gttgctgcta ttttaaagga gacacaagct gaaatcaatg aagagacatc
    16741 acttactgtg atgggtgttg attctctcat ggtcttggaa ttgcgaaatc gagttcaagc
    16801 tgacttgggt gttgacatct ctgttgcgga tttgatggga gatataaata ttagtcgtct
    16861 ggcaatcaag gtgagtgaac tactacatcg gaatgctcaa ggtgctcaag atctagagag
    16921 taagatggat ggcgacaatt tacaagagat agcgcttcag gacaaaaaaa tgagggaagg
    16981 taggttatga acttatcaga gtttttacaa gagcttgtca tcagcggctg gcaattttgg
    17041 gctgaagagg ggcaagtctg tttccaggct ccagatgctg actcaacaga tcaagtgtta
    17101 gcccagctca agcaacacaa acgagacatt ctcacaattt tgcaggagca cccagaagtt
    17161 ctccaggttt accctcttgg ttacggtcaa cagggcatct ggtttctgtg gcaactcttc
    17221 ccagacaacc ctaattacaa tgtttcattt gccactcgca tatattccca agtcaatgtt
    17281 acgacttggc aacagacgtt tgaggcgtta aggaagcgcc atccattgct gtgtagcact
    17341 ttccctaaat gtggggagac cccgattcga cagcattccg agcaactcga ctttgtgcag
    17401 attgacgcat ctacttggga tgagaatgaa ttgcagaccc aagttgtggc agcgcatcgg
    17461 catccctttg atctacaaac cgatcctgtg atgcgggtta gatggttcac gagatcagaa
    17521 caagagcata ttttgttgct taccatccat cacattgctt gggatggttc atctgccaat
    17581 ataattgtca aggaactctc agaactctat caagcccact gtgcaggtgt tgccgttgat
    17641 ctgccgtccc tgcagcatac ctaccaggat tatgttaagt ggcaacagca attagtggag
    17701 ggctcaaaag gagaaagcct gtggacctac tggcaacagc aactggcagg ggagttaccg
    17761 gtgttaaatt tgccaactga ccggccacat cctccaattc aaactaataa tggtgcggtt
    17821 taccggttcc agttacctga gcatttggta acacaggtca aagctctgag tcaagcagaa
    17881 ggggcaaccc tttacatgac gctcttagct gcatttcaag tattactgca tcgttataca
    17941 gggcaagaag atattctggt gggttctcca acctctggtc gaaccagacc ggagtttacc
    18001 tcagtggtgg gttattttgt tgactcgatg gtaatgcgag ctaaggtgtc agggagcctc
    18061 agttttcgag agtttttgac ccaagttcgt cagacggtta ttgatgcatt agcccaccag
    18121 gattatccct tttctttgtt agttgaaaaa ttgcaaccgg agcgcgatct cagccgttcc
    18181 cccattttcc aagtcttctt tggactccat aatttcctac agtccgaaac gcaacagctg
    18241 ttcctgggtg aaacaaagac cttggttcat tggggtggaa tggaagttga aacatttcta
    18301 ttcgatcaat atgaaagcct agaagacctg gtgctggaaa ttatcgaaat taactcacaa
    18361 ctgtctgggt tcttcaagta caacactgac ctatttgatg agcagactat tgcccagatg
    18421 gctagtcatt tacaaacgtt gttagcaggg attgtcacgc atcctgaaca aaggttagag
    18481 tcattgcctt tgttaaccca ggcagagcag catcagttat tagttgaatg gaatcagacc
    18541 actactcatt atccgacaga caaatgtatt catcagttgt ttgaagaaca agtggagcag
    18601 acaccggatg ctattgcggt ggtttttaag gaagagaaac tcagctacca agagttgaat
    18661 atccgtgcaa atcaattagc tcggtatcta caaagtttag gcgtaagtcc agaggtattg
    18721 gtgggcgttt gtgtagagcg ttcattagaa atgatagtgg gattgttggg gattctcaaa
    18781 gcaggaggag tttatgtacc tttagatccc aagtatcccc aagaacgtct agactatatg
    18841 tttcgcgact cccaaatgtc ggtgttgcta actcaacaac agttactaac tttgttgcct
    18901 caatacgaag caaaggtagt ttgcttagat cgagattggc aaaaaattgt tactgaaaat
    18961 cctaaaaatg ttaccagtga agttacggca gaaaatttag cctatgtgat ctacacttca
    19021 ggttccacag gcaaacccaa aggagtaatg gtagcccata ttggactaca taacctactt
    19081 aaagttcaga ttcaagcctt taaagtcagc tcaaatagtc gagtgcttca gttcgcatct
    19141 ttaagcttcg atgcctcgat ctgggaaata gttatggctt taggttccgg tgccagtctg
    19201 tatctggaaa gccgagaaaa tttgttgcca ggagctagtt tgagtaagtg gctcaatgag
    19261 aaaaaaatca cccaccttac cctgcctccg tcagctctag cagtgatgca aaaagaggaa
    19321 ttaccatccc tccagactat agtcgtagca ggagaagcct gtccagcaga ggtaatatcc
    19381 caatggtcac aggggcgaca atttgtcaat gcctacggac caacagaatc aacagtctgt
    19441 gccacgatgg cagaatgttc accagagtac tcagtgctgc ccattggtca ccccatagct
    19501 aatacccaaa tctaccttct agacaacaat ttacaaccag ttccgatcgg cattcctgct
    19561 gaaatgtata tcggtggtat cggtttggct cgtggctacc tcaaccgtcc cgacttaacc
    19621 actcagaagt ttatccccaa ccctttcagt aacaaagcag aacagaggct ttataaaaca
    19681 ggggatttag cacgttattt accagatggc aacatcgaat tcttgggtag gatcgaccat
    19741 caagtaaaaa tacgaggatt ccgcattgaa actgccgaaa ttgaagcggt actaaatcaa
    19801 aatcccacgg taaaacaaac agtagtagta gccagagaag acaaaccagg agacaaacat
    19861 ctatgtgcct atatagtggc tcaaatggaa acggcaacca actccaaccc agaactatca
    19921 gagactcacc tcaacagttg gcaagaaata ttcaaccaac aaatatactc tcaactaagt
    19981 gaagtcacag acccactgtt caacactact ggttacttaa gcaactacga caagcaaccc
    20041 atacccgaag cacaaatgcg agactgggcg gaggatatag taactcaagt cttagccaac
    20101 aaacccaatt cagtgtggga agtaggttgt ggcacaggaa tgctgctatt taaaatagcc
    20161 ccccacacac gggcttatta cggcaccgat atctcagaag tgtcgttgaa gtatatccaa
    20221 acacaaatag cacagcaacc ggacaaatat gctcatgtca ccttagctca gaaagcagca
    20281 gaagagatgg cagacattgc cgataacagc tttgatgtag tgcttctaag ctccatagtc
    20341 cagtatttcc caagtgtaga gtatctgttg caagtaatct ctaatagtat ccgggtagtc
    20401 aaaccaggag gaatgatttt cctaggggat atccgctctt tgccactaat gagggcattt
    20461 cacacttcgg tgcaactgca caaagctccc ccatcactct ctgtgcaaca actaaagcaa
    20521 ggcatataca ggcttatgca acaggagaca gagttgttgg tctcaccaga gttgtttgtc
    20581 gccctcaaag acacctatcc agaaatcact catgtacaga tccgtttaca gaggggaagc
    20641 gaacacaacg agctgaataa ataccgttac agtgtgctac tgcacataca ggctaaacct
    20701 acatcagtaa tcgttgcacc agtagagaat ggtgtgggta tgtcaatgga agacattgaa
    20761 gtatatctgg gacaacagca accagaatca atctgcttta gtagtttgac taatggtcgg
    20821 gtggcaacag atatggctgc ggtagagttg ctctcacaag tagagtcaaa actgaatgtg
    20881 cagcagttga gacaacagtt acggcagaag ctagtcaatg gtatcgaacc agaacagcta
    20941 catcaactga gcgcctcttt ggggtatgaa ctagagttgt gttggtcaca taagacggaa
    21001 ggatgttttg atgcagtatt tgtgcgaagc tccttagccc cagaagcgat ggtattaaca
    21061 ccactaactc aacaatcagt ggtagggggg aactggcatc gttatggcaa taatcccttg
    21121 gcttctgtaa caggcaaaca actaataccg cagtggagga agtatctgga ggagcggttg
    21181 ccggagtata tggtgccgag taggtacgtg attttgccac aactgccatt gacacccaat
    21241 ggcaaggtaa accgcaaggc attgcctgca cccgataata ccagtagtag gtcaaccgag
    21301 ttcgtggctc ctgagactag cacagagaaa gccttagctg caatttgggc agaggtgttg
    21361 agtatccaac aggtgggtat acatgacaac ttttttgaat cgggtggaca ttccttgctg
    21421 gctacccaag ttgtgtctcg gatcagacaa gctcttggaa aggaactgac tttacagcgt
    21481 ttattggaat cccccaccat tgccgaatta gactcagcct tagtccaatt acctagggtt
    21541 gaagattcac caaagcaaaa gcctgatggt cttttaccca caattgtgcc tgcgccaagc
    21601 cagcgctatc aaccctttcc cctcaccgag attcaacaag cttattggct cggccgcaat
    21661 tcgcactttg acttgggtaa tattaccacg catggttatc tggaactgga ctgtgagaat
    21721 ttagctttag accggttaag tcaggcttgg cagcaagtaa tagaccatca tgacatgctg
    21781 cgaatggtga ttctacccaa tggtgaacag caagtccttg aacaggttta cccctatcag
    21841 attgaagttt tagacttgcg cggtcaacca gaacaaatcg tctcaaccga actagaaacc
    21901 attcgttatc gcctgtccca cgagatgttc cccgctggag agtggccact atttaagatt
    21961 cgtgtgactc gcctagcgga tcagcgttac cgcttacact ggagctttga tgccctaatt
    22021 gctgatgcct ggagcatgat cattgtttgg caacaatggc tgcagctata ccagaaccca
    22081 gacagtttcc taccaaaatt agacctcaca tttcgggact atgtgttagc agaactgagt
    22141 ctcaaagaca cgccccaata tcgacgctct caacagtatt ggtggaatcg cttagagaca
    22201 ctcccccctg caccagaact tcccttggtc aagcaaactg ccacactaga gcaacctgaa
    22261 tttaattgtt atcgggctga actgtctgcc ccagattggc agcaattgca agccagggca
    22321 aaacaagcca gtttgacacc gtcaggggtc ttgttagccg cgtttgccga tttcctagcc
    22381 tattggagca aaagtcccaa attcacgatc aatctcaccc tctttaaccg gctacctttg
    22441 catccccaag tcaatgattt agtgggagac ttcacttccc tgacactctt agaggtcaat
    22501 caaaaaaacg cagctccctt tgctcagcgt gctcaacgtc tccagggaca actttggcaa
    22561 gacctagacc accgctatgt tgggggcgtt gaggtgcaac gagaacttcg ccgtcagcgc
    22621 ggtagttatc aacccatggg ggttgtattt accagtacgc tggcgctgaa tacgtcggca
    22681 gagaagggat tgccgtccaa tgaatggcac gcttggccat tcgaccaatt gggagaaact
    22741 gtttatatgg tctctaaaac ccctcaagtg tggctagaca attctgttgc tgaacaaaat
    22801 ggtgccttac tcctaatctg gaatgtagtc gaagacctct tcccagaggg gttcctcaat
    22861 gacatgttca caagctacta ccattggttg caacagctcg caacctccga tgtggcttgg
    22921 gcgcagactt gccctcaact actgcccctc tctcaactta cccaacgcct ccaagttaat
    22981 gaaacctatg cccctgtttc tgaagagacc ctccataatt tgtttgtgaa gcaagttcag
    23041 cagcgaccag aggcgatcgc cctcatcacc ccgcaacgca ccctcaccta ccatgaactc
    23101 tacaccgaag ctcaggcgct cggccagcaa gttcagcaat tgggagccac ccccaacacc
    23161 ctagtagccg tgctcatgga aaaaggctgg gagcaaatcg ttgctgtctt aggcattttg
    23221 atggctggtg cagcctatct ccccattgat gccgccctgc cccaggagcg tcaatggtct
    23281 ttgctggagc aaggagaagt caaactggtc gtgacacaag ctgccctaaa cgctagctta
    23341 ggattgccag accacctgca ctgcctggtg gttgcttccc aaccacagga gatcatagac
    23401 actcccctgg aggcaaacgt tagcagcagc gatttagcct atgtgatctt tacctccggt
    23461 tctacaggaa cacccaaagg ggtgatgatc gatcaccgag gagccgttaa caccatccaa
    23521 gatattaacc aacggtttga cgttcagccc actgaccgaa tgctggcggt ctctgccctc
    23581 aactttgacc tgtctgtcta cgatatcttt ggcctcctgg cagcgggggg caccctagtc
    23641 atgcccactc cagaggcagc caaagaccca gtccattggg ttgagttaat gacgacccat
    23701 caagtcaccc tctggaacac tgtcccagcc ctgatgcaga tgctagtgga atatctgtct
    23761 gagcacccag accaagtaac tgaggacctc cgacttgccc tgttgagtgg tgattggatt
    23821 ccactcaatt taccgaccca aatccaatca ttatggcccc aaggacaggt ggtcagtctg
    23881 gggggagcca cagaggcttc aatttggtct gtgtactatc ccatcactac cgtagagccg
    23941 gaatggaaga gcattcccta cggcaaacct ctagtgaatc aaagcctaca tgtgctcaat
    24001 cacaatctgg acccttgtcc taattgggtt ccaggtcagc tctacattgg tgggattggt
    24061 ctggcccagg gctattggcg ggatgagcaa aaaacgaatg ccagctttat cctgcatccc
    24121 cagactggag agcgcttgta taaaacgggt gatttggccc gctacttacc cgacggcaac
    24181 agtgaatttt tgggtcggga ggatttccaa gtcaaaatca gtggttatcg aattgaactc
    24241 ggtgagattg aggcaaccct gctggggcat gctacagtta aggaaaccgt tgtggctgct
    24301 gtgggtgaac tacagagtaa gcagttggtc gcctatgtgg tctttcactc agaatcatca
    24361 tctgactctg ccacagaaga cgtccacgat gacatgcgca tcgacgaact gcgtcactac
    24421 ttgcagcagc agttgccaga gtatatggtc ccgccgagtt acatggtcct cgatgccctg
    24481 cccctaacgg caaatggtaa ggtcgatcgc aaacgattgc ccacccctga attaatcagc
    24541 gatcattact cccctgatac ctacattccc ccacgcaatc accaagagct gcaactggtg
    24601 aagctatggg aggagatttt agaggttcaa cccattgggg tgggcagtca tttctttgac
    24661 ttgggggggc actccctgtt ggccgtgcgc ttaatgaatc gcatcgagca ggactttggg
    24721 cgctcgctgc ccttggcgac tctatttcag gccccaacca ttgagcaact ggccgtgatc
    24781 ttgcagcagg agcagggggt gcccacccta tctcccctgg ttcccattca gactcagggc
    24841 aaccaaccgc ccatcttctg tgtccaccct gctggtggga cggtcttttg ctacctggag
    24901 ctgtcccaac tgctcggtgc aaaccagccc ttctatggat tgcaatccct ggggcaacag
    24961 gaaggacaag ctccactgac aacggtggaa gagatggcca acgtctacct cgctgccatc
    25021 cgcgaagtcc aaccccaagg tccttaccta ctcatgggtt ggtcttttgg tgggatggtt
    25081 gccttgcaga tggcccacga tttgctctcc caaggtgagc aggttgcatt tctgggcctg
    25141 ttggatacct atgcaccggc ccacatgcct gatgagcaag tcttatcaga agatgtggaa
    25201 gtgctgcttg agctctttgg cggacctctc tccctcgatt gggaagtact ccgagatttg
    25261 ccctcggagc aacaatctgc cttgatttgg gagcaagctc accaggcgaa cctagtacca
    25321 ccagatttgg gggcagctca gattgagcgt cttctccagt tgatgaagct caatcacaag
    25381 gccatgcgca gttactctcc ccctgactat ccagatgtga tcacactgct gcacgctgaa
    25441 gctggttcag tggcagtatc ctcaacggaa gtgacaacag atcctacatt gggttggcaa
    25501 gcgatctcgc cctcaaaggt ggaggtccat accattcctg gttatcacga atatatggta
    25561 tatcagccca cagtcgtcat tgtggctgag accatcaaag ccgatattga aaaagggctc
    25621 aataccgatg ttgagacttc atctaaatga caatcttttg tttgtacatg aattaaaaaa
    25681 gggtaacgat atctcatgct gaaaaacttt gacattattg atgccgacag ccacgtctta
    25741 gagcccgacg atctctggga aaaatactta gaccctcagt ttaaagactt agcacctaaa
    25801 gacaatcaat ttgagggaaa atccatcatg tacaagacgc cagatgtcgt agtggcagaa
    25861 ggtcggcgtt tatttgaaga gaaccccgat cgctataaag ggggctataa tccccaagcc
    25921 cgcgttgagc taatggaaaa aatggggtct gacgtgacct ttttgtaccc aacaatcggg
    25981 ttgtttatgt gggcgattga caccatggac tcgaaactgg ctgacgctct ggtccgagcc
    26041 tataataatt ggctacagga cttttgcagt catgaccccc aaaagttaag gggggtgggt
    26101 gccattagcc aacatgaccc cgaagacatg gtaccagagt tgcagcgaat tgcagagttt
    26161 ggttggcgag cggtctttat ccgtcccaat ccagtcaagg gaaaactgtt aagtgatcca
    26221 gcctacgaac cgttttggag tgagtgcgaa cgtctcaaca tcgccgtcac gattcatgaa
    26281 ggaacccata gccgcctccc taccgccggg gcggatcggt ttcattctcg ttttgcgctt
    26341 catacctgct cccatcccct ggagatgatg atggggctat tggccatgat tgagggaggg
    26401 gttttagagc gtcatcctca attgagggta ggtttgtttg aagctgggtg tggttggctg
    26461 ccctactggc tatggcgaat ggatgagaaa tatgaaaatc tcgtctatga agtcaaggat
    26521 aatgtcaaga tgaagccctc tgaatatttc caccgtcagt gcttcattgg tgtcgaaaca
    26581 tcagaaccct atatacccga gttaatccag tacatcggag cagataaatt attgtttggg
    26641 tctgatttcc ctcacatgga tcatccgaac tttatcgaaa gtgtcgatga ggcactggca
    26701 ctgaaagagc gtctccctga ggagacaatt cacaaaattc tccatgacaa tcccttgaat
    26761 tactacgggc taacatagcg gcgttgctga atcaagtaat ggataggagt agagtgggca
    26821 tcctgcccgc tcgaaaataa gcatgaaact ggcaaaatgc cagttccagg caagatgccc
    26881 attntacagg tgcgacccaa gggtgagtaa atcgcccttg gaggcgcgca cctactctta
    26941 aaatcattat attattcagc aacgccggat tttttcccta ttccctattc cctactccct
    27001 attccctgtt ccctactccc tgttccctgt tcccttttca cttttcactt ttataaaacc
    27061 acctctaata ccacggtttg gatcgcgaag ttgaatatta tcttctagtt caaatgcaca
    27121 agggagttta gcagaccagc atagctcatg ctcttctgga gagatatctt gtggagaaaa
    27181 ataattaata ccattgactt gtttttttac taaatctgac gtcatcatct ggggagggat
    27241 aatcagtcga taggacgttt tttgattcaa aacaataact aaggtaataa gagataaagc
    27301 taaataacta gttatcctaa atatcggagg aattatccat aactttgata ccggtagttt
    27361 tttggtaatc agtaaattta aatttccgat tttttgatga caaactatag taatatataa
    27421 accaggtaga agaattagat atcctagtcc aaatctgatc acaggagcat aaagcatcat
    27481 aaataaagtt cccgaaatag ctaaacctaa gacccaaatc aaaccccaga ggcgatgaat
    27541 gattgatgtg cggagaatat agatggctaa taaaattgaa attaaaatta ttccagtcgc
    27601 aatttgattt agagtactag aactgaacca ctgccaaaat aaccaaagcc agggatttga
    27661 atttggggga ggtgagccaa accaggttcc ccagccgcga gtgttttcag caactgcttc
    27721 agcgtcttcc gctgtccaag accagggtaa atccagacag aagaaggatg atggaaaaag
    27781 tgggcaacca gaggtgatga tattgacagc gcacatgggt gataagagta aactcgtgat
    27841 gacaccacct atcactagtc gttgcacaca aaacctactg aaaacagtat aaaaaataac
    27901 tgatatgaat aataggggta gagaagtaag ctttatggtt acagctccag ctgctaaaat
    27961 cagtgggata aattcatcgt aaaatttatt attaaattta tttttaaaac tagaattttt
    28021 accccgagtt acggatgatg agcgatggtg agcaatgatt aaaattgccc aagcgatgat
    28081 tacggtgagg aaaattactg ggatatctgg cgatggagat accaggatat ctgacatcaa
    28141 actcgataga gctaggagag ggagtacaat caatgagcag atgacgataa accagtcact
    28201 gagctgtgct ttattggtga atagttgagc taaagcaatc agaaagtgta ctattgcgag
    28261 aagaaaggca aagccattgg ttatcgcact aacttgagca tcgaaaattg gagggttaaa
    28321 cggagcagcg agcgcaaacc acgatgaggt aaaaccaagc tgctgaagga gcagggcgat
    28381 acctggcact gctccatact cggacaacca tcggatggct ccatagtgat agagacctgt
    28441 gtcaagccaa gttacttgtc ggctggtgaa tgctgcgaca ccaaattcta aggtcaacaa
    28501 tcccaaggct aggttgggaa acagcatgaa acatagatta gcaatttcat cgcgggtagg
    28561 ttgtgatgtc agagacaata aactcagact aacagcggta caccagccta cccaggaatt
    28621 gaggggaaat actagggagg ttgctagcag tgcaatggac agcacaacga tgcccaacca
    28681 cactgctgca ataatgcgat cgctaactcg tttaaaggaa tccgcttgca gtacattcag
    28741 cacagcagtt ccgatcaagt agcaaggaat aagtagaaaa ttccaagtcg tgataaagta
    28801 gaacatgcca atagcctata caggctgaaa aactgagtcc tctactgaat cctgtttttg
    28861 ctttaactct tctgtggtaa attcttcata gtaagaacgc tcagtattta cctgccacag
    28921 atcatgattt tcccccagta agttcttaac tgctagcatt ccggttaaca tcgaatggtc
    28981 ttgattgttg tagcgatgca tcccattacg tccaatggtt tgtaggttat caaagtctgc
    29041 taaaaaatct tgaatcactt gtaaatgctg acgataatca cggtcgtaaa ctgggtaagc
    29101 tttaggttgg cgcaacacag taccatcctc tacagccttg gcatccgcca gacctaaact
    29161 cgccaattca cgggtggcta aatccagcaa tttgggatca gatagattcc agatttcatc
    29221 tccctcatta cagaagtatt ctaaacccag acaggtcttg ctaggatccg ataccatttt
    29281 tggactccaa ttcttaaaat tttggatgcg acccactttc acctctggac tatggatata
    29341 aatccactga tcaggaaata gatctttagc atcaataatg agcgctacaa taataaaagc
    29401 tcgataagat agggattttg ctgcttcgat taccgctggt gggggaggtg ggtcgagttt
    29461 tttaaccagt gctgtcactg gcatactgga gatgaaatgg tctccagaga tactgatagt
    29521 tttttcatcc tgcaaagcag taatgctttt gatatgattg ccatctcgtt gaatactagt
    29581 cactacagta ttcagtctta cctgaccacc ttgattatct actgcttgct gaaatttttc
    29641 ccacatcatc cctggtccaa gtagcgggta atcaaattcc ttaatcaagc ttttgctatt
    29701 ttgacttccg aacaaagcat tgatgattgc tcgttttaga gataattttt gaattcgctg
    29761 tgctgcccat tctgcttgaa ttttatcaca gggtatgccc catactttct ccgtataagt
    29821 tttaaaaaat agtctgtata aacgacgacc aaagcgatcg cttacccatt cttcaaaggt
    29881 ttcaggttca tgccaaggtc gcaattttgc cttgattttt gccttgaagt agctgagcaa
    29941 cataaccaga ctggtaatga tgcctagatt cgatagggtg ttaaagattg agaggggata
    30001 gtcgtagaat ttaccctggt aataaatgcg tgacatgcgg ggaactttga taaaatcttc
    30061 ccctaaaacc tcttgccaac gttgatgcgc tgcttctact ttggtataga agcgatgacc
    30121 accaatatcg aagcgatagc ctttgtagac ttcggtgcga gcaataccac cgactttatt
    30181 ggatttttct agaacgatag atttaatgcc ttgtttaacc aggtcatagg cagctgtaag
    30241 accagccggt cctgcgcctg taatcactac gggataatgt tccattgatt aaaaatagtg
    30301 cgtcagtggt gagtgcgtca gtggtgagtg tttagtgctt agtaggacaa tattgatttt
    30361 tattccatag cgatagcaat tctaggttaa acctaaggtt aaacgttatt ttaaacgtcg
    30421 atagtaactg ttattgttca ggattttaat actcataaat aaacccgatt ttagtttatt
    30481 tttaaataaa gatttatagc gtttatcata cttatgatgt acattcattt ttattaccgt
    30541 tactccctac tccctactcc ctactcccta ctccctaaaa cccactacga aagtacctca
    30601 accaatttat ccctgctata aacttgatag cttaggcaag tatatccgag gttgtaggta
    30661 cttttgaaag caatgacgaa ctataccaat ggcaaacgca agtccgctgt aaaagtaata
    30721 cagccagtgc catggaatgg ttcgtatagt gaatagtaga ccacgctttt gataaaagaa
    30781 ttggtagaca ggtctgttga gtactagcag ggcgagacta aatacacaag tagccatagc
    30841 aatcagagta ctagaccacc aataagctgt aactaaagca cctagtagag catagaccaa
    30901 caccacacta atacgactag acagctttag gttcaagtca ctgataaact cacgacagtt
    30961 ttccggactt gcgtcgcgaa ccttgagaat tacggcagtc cagggcaagg cgcggtagaa
    31021 aaagtcagct ctaaggagag aaattatgcc ccagggcttg agatgtttca cccgtagagt
    31081 cttacacagc ttaatcctgt aaccttcttg cttgagtcga tagcctaact caatatcttc
    31141 aatacagggt tgacgataat tttcctcaaa gccacccatg gcaataaaga tgtcacgacg
    31201 gattgcgcca caggcacccc aaaaggtaaa tgcttcttca gatgcagttt gatgagtgta
    31261 gtggtggagt aaatttttgt actgggaaag gaaattagca gcaccgggag aatcgtcata
    31321 agaaccaatt aaagcggtta aattaggttc attattaaaa attttcacca cttgaccaat
    31381 agtatccgga tagatggcta catcagcatc tataaaaaac aggatatcgg tctgtgctac
    31441 tttagctccc aggtttcggg ctttagccgg accccctgct gtgggcaatc gaattactgt
    31501 ggctccaaag tcttgggcta gacgccatga gccatcagta tcgccgtcag ctactacaat
    31561 cacttgatcg ggagggggtg cagcttgaga tagtctggca agacattgac gaaagtcttc
    31621 ccctccgttg tatacgggga tgatgacgga gatagttagt ttagcagagt caaccattct
    31681 ttagagaatt taccttcaat tactgattga gattttgaga ttaaatcgtt actatgcatc
    31741 tcaataatac cctcgtatag tttaacatta ttttagttaa aattattaga ttacactaag
    31801 ttttacaaac tagtttattg gctttaacaa aactatataa gaatcaccag tagggatttt
    31861 tttaaaaaaa aatcctgaat tgactaagta actctgtact tgtaatacag gttgtgtcta
    31921 caggttgagc agtcagccat ccgctatcag cagtcagccc atagtcagcc catttgatat
    31981 agctaaacgc tgatagctaa attaaaagct ttgctgaatc ttcgaatgaa taggagtaga
    32041 gtgggcatcc tgcccgcccg aaaatatatt gaaactggca agatgccagt tccacggcaa
    32101 gatgcccatt ccacagcaag atgcccattc cacagcaaga tgcccattcc acagcaagat
    32161 gcccattcca cagcaagatg cccattccac aaaactctta aaatcattcc attattaagc
    32221 aacgctaaat taaaaactca gtttatccct gtggaaagta taaatataaa atttaaatca
    32281 ccaaatgtcg gttgttaaaa cagttgatag cttaccactg gtttcagtga ttatccctgc
    32341 ctataataca gagcagttta ttgaaatcac attacagtct gttctttctc agacctataa
    32401 aaacctggaa ttgatagtgg tagatgacgg ttctcaagac cggacagctg agattgttca
    32461 atctattgct aagcaagatc agcgtgttat cttactacaa caaccaaatt taggggtggc
    32521 tgctgctcgg aatttaggga ttcaaaacac taagggagac tatatcgctc ccctggatgc
    32581 tgatgatatt tggtatccgc aaaatttaga aaagcaaatg aaacgcttct tggcaacaga
    32641 tccagcggta gggttggttt atgcttggtc ggtggatatt gatgaggaaa attcactgac
    32701 tggagatttc cgtgcttcaa gtatagaggg aaaggtttat aaaactctgg tatgtcataa
    32761 ctttttaggc aatgctagtg catctatgat tcgcgcctgt tgttttgaga ccgttggtgg
    32821 ctacaactgt caactgaagg cacaacaggc tcaggggtgt gaggattggg agctctattt
    32881 gcgaattgca gaacattatg aatttgctgt tgtgccggaa tttctgattg gctatcgcaa
    32941 aattgttagt agtatgtctc gcgactacag ccaaatggct aagtctcatg gtttgatgct
    33001 acgtgacgtt caacaaaggc atccagagat tccagcagcg ctttatcgat tgtctaagag
    33061 tagtttttat atgtatttgg cacgacaaag tagtcagtgt agtagcgatc gcagtacgtt
    33121 attttggcta tctcaagctt taaaagctga ttttattacg cctatttttc gctatgggtt
    33181 gtatatcttg tcccttaaaa gcttattgag aattatcact aagcttaaat ccggtaatta
    33241 tgttaataaa ccgggtgtag gcgtaagtcc tgcggattta aataaacgcc gatggagtct
    33301 atatttcaag ctcttgcttg gaaatttatt acaccgttca ctgctgataa tataaggaag
    33361 ttttggttat gctttatcca atcaaagtgg tggacattga attgagccgc cccctgacta
    33421 ctcttgatgg tttagatggc tatattgcag tgaaaggact ggttcgcttc catggtgcgc
    33481 caattggata tgttcaagca ccgattacta atggttactg cacagcagaa accttaagta
    33541 aacttattct ggaaggccat agcgagacga ttatcaatcg ccttttgtac aatggattat
    33601 ccttacccct cggacgcgaa aggttgtgtc ttgaggattt gtttgatgtg tcaccaccag
    33661 agtataaggg caagttgccg ttagtaacag ttgcggtttg tactcgcgat cgcactgctg
    33721 atcttgctct atgtttagac gctatcaatc aactcgatta tccttactta gatattttag
    33781 ttgttgataa tgctcccacc agtgatgaca ctaataaact ggtggaaact tatactaatg
    33841 ttcgttatat ttgtgaacct cgtccgggtt tagattgggc gagaaaccga gctgttcttg
    33901 aagctaaagg agacataatt gcctatactg atgatgatgt agtggttgat tcaggatggg
    33961 taaaagcatt agcgctagtg tttattaaac atcctgacgt tatggcagtg actgggttag
    34021 ttgtgcctta tgaattggaa accgaagcac aagtgctgtt tgaaatgtat ggcggcttcg
    34081 ggcgaggcat gaggcgtaag tggtatcagg ttaatcgagg caacaaaatg ccttggaaat
    34141 tcctgggtac tggacaattc ggtacagggg caaacatggc ttatcgncgc tcagtatttg
    34201 atgatattgg tttctttgac cctgctttag atgtgggtac tgtgactaat ggtggtggtg
    34261 atttagaaat gtttttccgg gtggttaagg aaggacatac cctcgtctat gagcctagtg
    34321 ccatagtgcg ccatcgacat cgacgggatt atgctaagtt gcgtacgcaa attactaata
    34381 acagtattgg tctgttttct tactgtatcc gtagtctctt tgcctatcca gatgagtgtc
    34441 tttctttctt gtcgattttg ctctggtgga tagtgtattg gaatttaaga cgtctgtgga
    34501 ttggtttcaa acatcccact cgcttcccac gggatttaat tctggctgat taaangctgc
    34561 ttcattggtt taactcgcta tcacaaagtc tcgccacact gctgctgaga ttactaaatc
    34621 tttcggtgag caagaacggg aaacagaaga ggatgtagat agtgctccct acccgatttt
    34681 ttctgaccct atctttcctg ctctgactaa ggaagaaatc caaaaggtta aaaccaatcc
    34741 aggtatggca gtgcggactg tggatctacg ggaaccttta caggcattaa ctgatgttaa
    34801 agagtactca tcagtacgag tctttgtgaa atggcatgat cagcttttag gtagcgttga
    34861 tattcctaac cctgatcgag ggattagcaa gagtcgctta attgaggtta ttgtcaatca
    34921 gtttggtatg aagctgctgg aagtaaacct taacttcagt aggtattact gctatactca
    34981 agcaatatct atcttaaata atcactataa agtcacggat aaagagactg atttactaac
    35041 ctgtttacct gataaaatac caatctctat tatcatcgct acctatgatc gaccccaaga
    35101 tttgcggang tgtttgtgca gcatagttgc ccaaaagtat actcgacaat tggaaattat
    35161 tgtagttgat aatcatcccg cttctggttt gactccacca gtggttgctg agtttcctga
    35221 tgttgtctta gttagtgaat cccgtcaggg cactagctta tgctcgcaat gctggctttg
    35281 ttgctagtac tggggatatt gtgattgcga cggatgatga tgttactgtg ccaccggatt
    35341 ggttagaaaa actaatcgct ccttttgcta gagcggatgt gatgattgtc acaggtaatg
    35401 ttttgcccct acagttggaa accaatgccc agcagtgttt tgaaaattat ggcggcttgg
    35461 gacggggctt tgaggagttt gaggttaacg gagattggtt tgaatccttt tcacgccatg
    35521 ctgtaccaac ttggcagtta ggagcaaccg ctaatgctgc ttttcgtgcc agtatcttta
    35581 gtcatcccaa gattggtcta atgaacgaag ccctcggtcc cggtatgcct tcaggagttg
    35641 gtgaagatac ttacttattc tataaagtac ttaaagctgg ctacaccctc atctatgagc
    35701 caagcgctta tgtctggcat aagcatcgca ctgaaatggc agagctacat cgtcagcttt
    35761 acaactacag taaaggtcat gttgcttaca atctgaccac atggctacag gatggggatt
    35821 ggcgaggatt ggtgcaaata gtgctgggat tgccacttgc tcatttatct cgcatctatc
    35881 aacggctcag aggttggagc gattatccaa tctccctaat ctggttggaa atgacaggta
    35941 atctggctgg agtttggtct ttgtggcagt cccatctgcg ggttaaacgt gaaggtcgta
    36001 tagcaaaggg agtagggagt agggagtcgg gagtcgggag tagggagtcg ggagtcggga
    36061 gtcgggagtc gggagtaggg agtagggagt agggaacaaa aattatcaca atattgtttc
    36121 actctcgtaa aacaataatc tcagccaaag actgaaactt ttatttaatc aaggttttaa
    36181 gtttttttga ataactaaaa aattaaatca caatgggttg aataaagccc tatcaagctt
    36241 taatttactg ctttattaaa gtctaaaaaa atagtaatat agcattttaa aatagatcat
    36301 caaataatcg gatctatttc ctactattcc ctatttactg ctccctgctc cctgctccct
    36361 gctccctgct ctctaaaaac cagggagggc gaaattacct aaaccaattg acaactgctg
    36421 tcaaatgcta tattactcca atgtcttcaa tacaacatcg aaaatcaaaa ctcaaacaat
    36481 tttacaagtg gcggctttct tatctctatg atttgctacg agagctagtt aatcgggaga
    36541 tgaagctact ctacaaacgg tcagttttgg gagtagcttg gatgctgctt aatccactac
    36601 tccagctagc tgtattttcc tttgttttcc gttttgtatt gtcggttgat attcctcaat
    36661 atacctcctt tgcattttct ggtttgttgg tatggacatg gtttaacacg tctctttttc
    36721 aagccactgg ggtgattatt agtaatcgcc ccctgatccg acaaccgggt tttcccaacg
    36781 ctatcttacc ggtggttacc gtaacaacag gtctgattca ctttattcta gccctgccaa
    36841 tattagttat ctttctgtta atcgatggtg ttcagctaca gccagtaatt atactgttac
    36901 caatcctaca agctctacag ttttccgtta ccattagttt agcctatata ctagctgggc
    36961 ttaatgtaat atttcgcgac acccagcata ctatcggtgt acttctacag ctgttttttt
    37021 atctcacacc tattttttat gaaattacta atgtgcccaa aaattaccag tttttctatt
    37081 accttaaccc gatggtgcat ctggttaccg cctatcgcgc tgtactaatt aaaggaacac
    37141 caccggattg gatagctctg ctagttatgg ctttggtcac ggcagtgttt ttacctatcg
    37201 gtcttcaaat tttccggtgg cagagcgatc gctttgtgga ggaattatag atggttgatg
    37261 caattattgt tcaaggactc ggtaaacgct ttaactacta tcatcctgag cgaccgctta
    37321 ctattatgga ggcggcgctg tcgggttttc ggcatattat ggcagcggaa gggttttggg
    37381 cgttgcggaa tattacgttc aaggtttccc caggccaaat gctaggcatt ctcggtcaca
    37441 atggagcagg taaatcaacg ttattgcgct tgattggtgg ggttggaaaa ccggatgaag
    37501 ggaaggttag ggttaatggc tccattggag cgctgctgga tttgggggct ggtttccatc
    37561 cagatttgac tgggcgagaa aacgcttttg ttagtggtgt tgtagcaggt cttactcgtc
    37621 aagaggtggg gcggcgtttt gatgaaatcg tgacgtttgc tgaacttgag cagtttatcg
    37681 ataacccagt ccgcacttat agtacaggga tgcagatgcg gctggcgttt tcggtggctg
    37741 tacacacaga cccagatgtg atgctagttg atgagtttct gtccgttggg gatttggcat
    37801 ttcaggctaa gtgcttggaa cgaattgctc agttgaaaga gtctggctgt gctattgtcc
    37861 taatttctca cagtagcgag caaattgagc aactttgcga tcgcgctttg tggctacaac
    37921 aaggacaaat catggcttac ggtgagccaa aagtggtagc aggacagtat gtcaatcaaa
    37981 tgcgatcgca aacccagcaa cctactccca acagacctgc ccaactgact aggtctggtg
    38041 tggaactgcg aatgaatgaa aaccggtttg gctctctaga agtagaaatt accgatgtgc
    38101 tgctgttacc tagcttagag attaatagtg gtgattcctt ggccattgac attgagtact
    38161 tgtcacttca accaattgat ggactaattt ttagtgtcat cattagcact gaagatggtc
    38221 aaatctgtct tgagactaac acaactacca tgggagcatc cttaccaggt attaaaggta
    38281 aaggaaaaat aaaactccat ctatcccgct tagatttaaa cggtggtaag tattttgttg
    38341 atgttggggt ttatgaaccg aatcgggctt atacctatga ctaccattgg catgtgtatc
    38401 agcttttagt gcgttcaaaa gatagcgaaa aaggtattat tagcccaccg cttcgttggg
    38461 atgttgttga aggttgaaag ttggttgaag gtttaaattt ggttgaaggt tgaatgttgg
    38521 ttgaaggttg aatgttggtt gaaggttgaa tgttggttga aggttgaatg ttgggtgaag
    38581 gttgaaggtt gggtaaaagt tgaatgttga atgttgttcg cctttggcgt tcggtgaagg
    38641 gtaggtttaa tgttgcttga ttgttgactg aggaacaggt aataggcaac aggtaacaga
    38701 tttagcttta cgattcccga ttcccgattc ccgattcccg attcccgatt cccgattccc
    38761 gattcccgat tcccgattcc cgattcccga ttccccgatt cccgattccc cgattcccga
    38821 ttccccgatt ccccgattcc cgattccccg attcccgatt cccgattccc gattcccgat
    38881 tcccgattcc cgattcccga ttcccgattc ccgattccct ttgagcaaaa atttatcaaa
    38941 tctaaaacta ttgaaaaaaa tagtatatag attattaaag ctgattcaat caataagttt
    39001 agctatcttg attcttagtg tttctgtact gcccgtattt gctcaggaat ccttgaatgt
    39061 atctaatcag gatttgccta tggtatctac agccaatgat tcccagttag aactaactaa
    39121 attccaggat atagaaaaat ttagtgacga cttttttgtc aatcaaatgg cagaaaatca
    39181 tattcctggt gccgtattca ccttagtaaa agangacaag attctcttct cgaaaggcta
    39241 cggctacgct aaccttgagg ataagatacc ggttattcct aacaaaactc tgtttcgtgt
    39301 aggctctgta tctaaactag ttacctctac agcagtaatg caactagtcg agcaaggtaa
    39361 gcttaagcta catgaagata ttaaccagta tcttaagtaa tttcaaatta agactgataa
    39421 atttaagcca attacagttg atcatctctt aactcatact gatggattcg atgtagcttg
    39481 ggtgattggc ggagccactc gttgccagtc taagctgcta tccttagaaa aatttctcac
    39541 agaaaattta ccagagcgag tgcgaccacc aggtcaatta tatgtttatg gtgatgtagg
    39601 attagcattg gcaggttact tagtagaagt ggttgctgga attcctttca gtgaatatat
    39661 tgaccaaact atcctacaac ctttggatat gagtcaaagt agttttcagc aaccattacc
    39721 gtatcagctg gcagctaact tagctgtagg atatcggtac aaaaatggca attatctaaa
    39781 gcaagccttt acctgtaata aaagtgttcc tactacagct ttaactacta ctgctgaaga
    39841 catggcccac tttatgattg ctcatttaca gggaggtcgt tatcgtaaac agcgtatcct
    39901 gaatgatact acagtaaagg atatgcacca ccaacactat actaattttc cgaacattcc
    39961 tcaatcggca ggatctactt atggtttttt tgagcgcttt gtgaataatc aacggataat
    40021 tgagcatggc ggtagcatgt cagggtatac taatctggtg tttttaatcc cagaacaaaa
    40081 gttaggtttc tatattgctt acaatcgtaa cagtcttaat gagaatttgc gagacgactt
    40141 ggttgaacag ttttta
//
