BGC0000977: cyclopiazonic acid biosynthetic gene cluster from Aspergillus oryzae
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 34,298 nt. (total: 34,298 nt).
This entry is originally from NCBI GenBank AB506492.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000977
Short description cyclopiazonic acid biosynthetic gene cluster from Aspergillus oryzae
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
AB506492.1
via
Compounds
  • cyclopiazonic acid
  • 2-oxocyclopiazonic acid
Species Aspergillus oryzae [taxonomy]
References
Chemical products information
cyclopiazonic acid [synonyms: α-cyclopiazonic acid] Evidence: Mass spectrometry [1], Experimental values match with authentic standard [1]
Copy SMILES
C20H20N2O3
Chemical database entries
NPAtlas
PubCHEM
2-oxocyclopiazonic acid Evidence: Mass spectrometry [1], Experimental values match with authentic standard [1], NMR [1]
Copy SMILES
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAK26557.1
  • cpaT
1607 - 3212 (-) putative MFS multidrug transporter
    copy AA seq
    copy Nt seq
    • BAK26558.1
    • cpaM
    3720 - 5293 (-) hypothetical protein
      copy AA seq
      copy Nt seq
      • BAK26559.1
      • cpaH
      5675 - 7324 (+) cytochrome P450
        copy AA seq
        copy Nt seq
        • BAK26560.1
        • cpaO
        8571 - 9938 (+) FAD-dependent oxidoreductase
          copy AA seq
          copy Nt seq
          • BAK26561.1
          • cpaD
          10407 - 11784 (-) dimethylallyltryptophan synthase
            copy AA seq
            copy Nt seq
            • BAK26562.1
            • cpaA
            12739 - 24462 (+) PKS-NRPS hybrid
              copy AA seq
              copy Nt seq
              • BAK26563.1
              • cpaR
              24909 - 26761 (+) putative C6 transcription factor
                copy AA seq
                copy Nt seq
                Biosynthesis information
                Annotation changelog

                Entry version: next

                Date
                Changes
                Submitters
                Reviewers
                MIBiG v4 annotathon
                • (ID: D44UGPXERIZAXNCG2VXZP5I3)
                • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 3

                Date
                Changes
                Submitters
                Reviewers
                Linked new NPAtlas id for cyclopiazonic acid (npatlas:NPA015449)
                • (ID: 5UL74VURKJ25VSPPPO3H2NYB)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 2

                Date
                Changes
                Submitters
                Reviewers
                Migrated from v1.4
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 1

                Date
                Changes
                Submitters
                Reviewers
                Submitted
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                Detailed domain annotation
                Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                A domain glossary is available here, and an explanation of the visualisation is available here.
                Selected features only
                Show module domains
                Similar known gene clusters from MIBiG 4.0
                Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                Click on reference genes to show details of similarities to genes within the current region.
                Click on an accession to open that entry in the MiBIG database.