BGC0000985 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000985 (Tistrella mobilis KA081020-065)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	54,757

BGC0000985 - Region 1 - NRPS

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Location: 1 - 54,757 nt. (total: 54,757 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 54,758
Label		BGC0000985

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000985.1	0.89	NRP, Polyketide	didemnin B, nordidemnin B, didemnin X, didemnin Y	Tistrella mobilis KA081020-065
BGC0001135.1	0.34	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000389.1	0.33	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0002071.1	0.33	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0001844.1	0.33	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000427.1	0.33	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001758.1	0.32	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001050.1	0.32	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0001128.1	0.32	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001261.1	0.32	NRP	AM-toxin	Alternaria alternata

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000985.1	0.96	NRP, Polyketide	didemnin B, nordidemnin B, didemnin X, didemnin Y	Tistrella mobilis KA081020-065
BGC0001135.1	0.67	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000389.1	0.67	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0002071.1	0.67	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0001844.1	0.66	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000427.1	0.66	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001758.1	0.66	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001050.1	0.66	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0001128.1	0.65	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001261.1	0.65	NRP	AM-toxin	Alternaria alternata

Similar known gene clusters

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 54757:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gln - gln) + (pro) + (D-NMe-leu - thr - ile) + (leu) + (pro) + (NMe-tyr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TMO_c0602

Search NORINE for peptide: strict or relaxed

AMP-binding (466..852): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: DAWQFGLIDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 100% (strong)

AMP-binding (1513..1896): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAWQFGLIDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 100% (strong)

TMO_c0603

CAL_domain (738..1157): pk

minowa: AHBA

Prediction, score:

AHBA: 14.0
fatty_acid: 12.0
shikimic_acid: 0.0
NH2: 0.0
Acetyl-CoA: 0.0

TMO_c0604

Search NORINE for peptide: strict or relaxed

AMP-binding (523..911): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFAAqVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 90% (moderate)

TMO_c0605

Search NORINE for peptide: strict or relaxed

AMP-binding (249..642): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGhVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 90% (moderate)

AMP-binding (2212..2615): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

AMP-binding (3246..3653): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFlGITFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 90% (moderate)

TMO_c0607

CAL_domain (554..969): pk

minowa: shikimic_acid

Prediction, score:

shikimic_acid: 0.0
fatty_acid: 0.0
NH2: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

TMO_c0609

Search NORINE for peptide: strict or relaxed

AMP-binding (503..896): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

TMO_c0610

Search NORINE for peptide: strict or relaxed

AMP-binding (257..645): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFlAqVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 80% (moderate)

TMO_c0611

Search NORINE for peptide: strict or relaxed

AMP-binding (525..906): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DASTlAAVCK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 90% (moderate)