BGC0000988: epothilone B biosynthetic gene cluster from Sorangium cellulosum
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Location: 1 - 68,750 nt. (total: 68,750 nt).
This entry is originally from NCBI GenBank AF210843.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0000988
Short description epothilone B biosynthetic gene cluster from Sorangium cellulosum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
AF210843.1
via
Compounds
  • epothilone B
Species Sorangium cellulosum [taxonomy]
References
Chemical products information
epothilone B Evidence:
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C27H41N1O6S1
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAF26904.1
 <5 - 1826 (+) unknown
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    • AAF26905.1
    		 1900 - 3171 (-) unknown
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      • AAF26906.1
      		 3415 - 5556 (+) unknown
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        • AAF26907.1
        		 5612 - 5992 (-) unknown
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          • AAF26908.1
          		 6226 - 6675 (+) unknown
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            • AAF26919.1
            • epoA
            		 7610 - 11875 (+) polyketide synthase
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              • AAF26925.1
              • epoP
              		 11872 - 16104 (+) nonribosomal peptide synthetase
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                • AAF26920.1
                • epoB
                		 16251 - 21749 (+) polyketide synthase
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                  • AAF26921.1
                  • epoC
                  		 21746 - 43519 (+) polyketide synthase
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                    • AAF26922.1
                    • epoD
                    		 43524 - 54920 (+) polyketide synthase
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                      • AAF26923.1
                      • epoE
                      		 54935 - 62254 (+) polyketide synthase
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                        • AAF26924.1
                        • epoF
                        		 62369 - 63628 (+) cytochrome P450
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                          • AAF26909.1
                          		 63779 - 64333 (+) unknown
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                            • AAF26910.1
                            		 63853 - 64290 (-) unknown
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                              • AAF26912.1
                              		 64287 - 64727 (-) unknown
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                                • AAF26911.1
                                		 64363 - 64920 (+) unknown
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                                  • AAF26914.1
                                  		 65008 - 65874 (-) unknown
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                                    • AAF26913.1
                                    		 65063 - 65767 (+) unknown
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                                      • AAF26915.1
                                      		 65871 - 66338 (-) unknown
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                                        • AAF26916.1
                                        		 66667 - 67137 (+) unknown
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                                          • AAF26917.1
                                          		 67334 - 68251 (+) putative transport protein
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                                            • AAF26918.1
                                            		 68346 - >68750 (+) unknown
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                                              Biosynthesis information

                                              No biosynthesis information available for this record.

                                              Annotation changelog

                                              Entry version: 4

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2022-10-07
                                              Update chemical activity to schema version 2.11
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 3

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2022-09-15
                                              Updated bioactivity data
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 2

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2019-10-16
                                              Migrated from v1.4
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              2019-10-16
                                              Updated compound(s) information (NPAtlas curation)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 1

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2015-06-12
                                              Submitted
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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