BGC0000991: epothilone biosynthetic gene cluster from Sorangium cellulosum
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Location: 1 - 58,733 nt. (total: 58,733 nt).
This entry is originally from NCBI GenBank AF217189.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0000991
Short description epothilone biosynthetic gene cluster from Sorangium cellulosum
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: AF217189.1
Compounds
  • epothilone
Species Sorangium cellulosum [taxonomy]
References
Chemical products information
epothilone
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C27H41N1O6S1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAF62878.1
 3 - 992 (+) putative transposase
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  • AAF62879.1
 989 - 1501 (+) putative transposase
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  • AAF62880.1
  • epoA
 1998 - 6263 (+) EpoA
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  • AAF62881.1
  • epoB
 6260 - 10492 (+) EpoB
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  • AAF62882.1
  • epoC
 10639 - 16137 (+) EpoC
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  • AAF62883.1
  • epoD
 16134 - 37907 (+) epoD
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  • AAF62884.1
  • epoE
 37912 - 49308 (+) EpoE
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  • AAF62885.1
  • epoF
 49323 - 56642 (+) EpoF
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  • AAF62886.1
  • epoK
 56757 - 58016 (+) EpoK
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  • AAF62887.1
 58194 - 58733 (+) putative membrane protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
epoB
Module ?
Specificity: cysteine
Evidence for specificity:
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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