BGC0000993: FR901228 biosynthetic gene cluster from Chromobacterium violaceum
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Location: 1 - 40,434 nt. (total: 40,434 nt).
This entry is originally from NCBI GenBank EF210776.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Polyketide
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000993
Short description FR901228 biosynthetic gene cluster from Chromobacterium violaceum
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP (Cyclic depsipeptide)
  • Polyketide (Macrolide)
Loci NCBI GenBank: EF210776.1
Compounds
  • FR901228
Species Chromobacterium violaceum [taxonomy]
References
Chemical products information
FR901228
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C24H36N4O6S2
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABP57738.1
 2 - 454 (+) 16S rRNA pseudouridine synthase
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  • ABP57739.1
 466 - 957 (+) MutT/nudix family phosphohydrolase
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  • ABP57740.1
 972 - 1544 (+) transcription elongation factor GreB
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  • ABP57741.1
  • depK
 1616 - 1873 (-) DepK
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  • ABP57742.1
  • depL
 1971 - 2438 (-) DepL
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  • ABP57743.1
  • depM
 2513 - 3682 (+) DepM
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  • ABP57744.1
  • depN
 4469 - 4666 (+) DepN
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  • ABP57745.1
  • depA
 5034 - 10127 (+) DepA
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  • ABP57746.1
  • depB
 10127 - 14788 (+) DepB
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  • ABP57747.1
  • depC
 14785 - 18336 (+) DepC
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  • ABP57748.1
  • depD
 18333 - 27506 (+) DepD
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  • ABP57749.1
  • depE
 27503 - 33181 (+) DepE
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  • ABP57750.1
  • depF
 33178 - 34350 (+) DepF
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  • ABP57751.1
  • depG
 34347 - 35312 (+) DepG
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  • ABP57752.1
  • depH
 35309 - 36268 (+) DepH
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  • ABP57753.1
  • depI
 36324 - 37238 (+) DepI
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  • ABP57754.1
  • depJ
 37235 - 37999 (+) DepJ
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  • ABP57755.1
 38068 - 39006 (-) hydrogen peroxid-inducible genes activator OxyR
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  • ABP57756.1
 39010 - 39267 (-) cell division topological specificity factor MinE
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  • ABP57757.1
 39271 - 40083 (-) septum site-determining protein MinD
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  • ABP57758.1
 40110 - >40433 (-) septum formation inhibitor MinC
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Polyketide-specific information
Subclass Macrolide
Starter unit Malonyl-CoA
Cyclic? yes
Release type
  • Macrolactamization
Polyketide-synthases
Genes Properties Modules
depJ Synthase subclass: Modular type I
Thioesterases:
  • depJ (Type II)
NRP-specific information
Subclass Cyclic depsipeptide
Cyclic? yes
Release type
  • Macrolactamization
NRP-synthases
Gene Modules
depA
Module ?
Specificity: cysteine
Evidence for specificity:
  • Structure-based inference
depD
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: cysteine
Evidence for specificity:
  • Structure-based inference
depE
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: DUUOEWRWRZA5NTLPQCYGT6Z6, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected gene identifiers
  • Added NRP substrate specificities
Detailed domain annotation
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