BGC0000994: FR-900520 biosynthetic gene cluster from Streptomyces hygroscopicus subsp. ascomyceticus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 77,534 nt. (total: 77,534 nt).
This entry is originally from NCBI GenBank AF235504.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000994
Short description FR-900520 biosynthetic gene cluster from Streptomyces hygroscopicus subsp. ascomyceticus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: AF235504.1
Compounds
  • FR-900520
Species Streptomyces hygroscopicus subsp. ascomyceticus [taxonomy]
References
Chemical products information
FR-900520
Copy SMILES
C43H69N1O12
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAF86380.1
  • fkbW
 412 - 1836 (-) FkbW
copy AA seq
copy Nt seq
  • AAF86381.1
  • fkbU
 2020 - 3579 (-) polyhydroxybutyrate depolymerase
copy AA seq
copy Nt seq
  • AAF86382.1
  • fkbR2
 3969 - 4496 (-) FkbR2
copy AA seq
copy Nt seq
  • AAF86383.1
  • fkbR1
 4595 - 5488 (-) FkbR1
copy AA seq
copy Nt seq
  • AAF86384.1
  • fkbE
 5601 - 6818 (+) FkbE
copy AA seq
copy Nt seq
  • AAF86385.1
  • fkbF
 6808 - 8052 (+) FkbF
copy AA seq
copy Nt seq
  • AAF86386.1
  • fkbG
 8156 - 8824 (+) FkbG
copy AA seq
copy Nt seq
  • AAF86387.1
  • fkbH
 8802 - 9884 (-) FkbH
copy AA seq
copy Nt seq
  • AAF86388.1
  • fkbI
 9895 - 10995 (-) FkbI
copy AA seq
copy Nt seq
  • AAF86389.1
  • fkbJ
 10988 - 11248 (-) FkbJ
copy AA seq
copy Nt seq
  • AAF86390.1
  • fkbK
 11245 - 12093 (-) FkbK
copy AA seq
copy Nt seq
  • AAF86391.1
  • fkbL
 12114 - 13151 (-) FkbL
copy AA seq
copy Nt seq
  • AAF86392.1
  • fkbC
 13214 - 23989 (-) FkbC
copy AA seq
copy Nt seq
  • AAF86393.1
  • fkbB
 23994 - 46571 (-) FkbB
copy AA seq
copy Nt seq
  • AAF86394.1
  • fkbO
 46752 - 47786 (+) FkbO
copy AA seq
copy Nt seq
  • AAF86395.1
  • fkbP
 47783 - 52270 (+) FkbP
copy AA seq
copy Nt seq
  • AAF86396.1
  • fkbA
 52273 - 71463 (+) FkbA
copy AA seq
copy Nt seq
  • AAF86397.1
  • fkbD
 71460 - 72626 (+) FkbD
copy AA seq
copy Nt seq
  • AAF86398.1
  • fkbM
 72623 - 73405 (+) FkbM
copy AA seq
copy Nt seq
  • AAF86399.1
  • fkbN
 73459 - 76200 (-) FkbN
copy AA seq
copy Nt seq
  • AAF86400.1
  • fkbQ
 76335 - 77078 (-) FkbQ
copy AA seq
copy Nt seq
  • AAF86401.1
  • fkbS
 77075 - >77533 (-) FkbS
copy AA seq
copy Nt seq
NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
fkbP
Module ?
Specificity: pipecolic acid
Evidence for specificity:
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.