BGC0000994: FR-900520 biosynthetic gene cluster from Streptomyces hygroscopicus subsp. ascomyceticus
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Location: 1 - 77,534 nt. (total: 77,534 nt).
This entry is originally from NCBI GenBank AF235504.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000994
Short description FR-900520 biosynthetic gene cluster from Streptomyces hygroscopicus subsp. ascomyceticus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: AF235504.1
Compounds
  • FR-900520
Species Streptomyces hygroscopicus subsp. ascomyceticus [taxonomy]
References
Chemical products information
FR-900520
Copy SMILES
C43H69N1O12
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAF86380.1
  • fkbW
412 - 1836 (-) FkbW
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  • AAF86381.1
  • fkbU
2020 - 3579 (-) polyhydroxybutyrate depolymerase
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  • AAF86382.1
  • fkbR2
3969 - 4496 (-) FkbR2
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  • AAF86383.1
  • fkbR1
4595 - 5488 (-) FkbR1
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  • AAF86384.1
  • fkbE
5601 - 6818 (+) FkbE
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  • AAF86385.1
  • fkbF
6808 - 8052 (+) FkbF
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  • AAF86386.1
  • fkbG
8156 - 8824 (+) FkbG
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  • AAF86387.1
  • fkbH
8802 - 9884 (-) FkbH
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  • AAF86388.1
  • fkbI
9895 - 10995 (-) FkbI
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  • AAF86389.1
  • fkbJ
10988 - 11248 (-) FkbJ
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  • AAF86390.1
  • fkbK
11245 - 12093 (-) FkbK
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  • AAF86391.1
  • fkbL
12114 - 13151 (-) FkbL
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  • AAF86392.1
  • fkbC
13214 - 23989 (-) FkbC
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  • AAF86393.1
  • fkbB
23994 - 46571 (-) FkbB
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  • AAF86394.1
  • fkbO
46752 - 47786 (+) FkbO
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  • AAF86395.1
  • fkbP
47783 - 52270 (+) FkbP
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  • AAF86396.1
  • fkbA
52273 - 71463 (+) FkbA
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  • AAF86397.1
  • fkbD
71460 - 72626 (+) FkbD
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  • AAF86398.1
  • fkbM
72623 - 73405 (+) FkbM
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  • AAF86399.1
  • fkbN
73459 - 76200 (-) FkbN
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  • AAF86400.1
  • fkbQ
76335 - 77078 (-) FkbQ
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  • AAF86401.1
  • fkbS
77075 - >77533 (-) FkbS
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
fkbP
Module ?
Specificity: pipecolic acid
Evidence for specificity:
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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