BGC0000995: FR901464 biosynthetic gene cluster from Pseudomonas sp. 2663
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Location: 11,932 - 92,515 nt. (total: 80,584 nt).
This entry is originally from NCBI GenBank HM047288.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000995
Short description FR901464 biosynthetic gene cluster from Pseudomonas sp. 2663
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
HM047288.1
11932 - 92515
via
Compounds
  • FR901464
Species Pseudomonas sp. 2663 [taxonomy]
References
Chemical products information
FR901464 Evidence:
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C27H41N1O8
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADH01482.1
  • fr9A
 11932 - 12816 (+) transcriptional regulator
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    • ADH01483.1
    • fr9B
    		 13131 - 14213 (+) acyltransferase
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      • ADH01484.1
      • fr9C
      		 14687 - 29872 (+) putative type-I PKS
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        • ADH01485.1
        • fr9D
        		 29945 - 35257 (+) putative mixed polyketide synthase/non-ribosomal peptide synthetase
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          • ADH01486.1
          • fr9E
          		 35257 - 38823 (+) polyketide synthase
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            • ADH01487.1
            • fr9F
            		 38867 - 53581 (+) polyketide synthase
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              • ADH01488.1
              • fr9G
              		 53637 - 62690 (+) polyketide synthase
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                • ADH01489.1
                • fr9H
                		 62806 - 70794 (+) type I polyketide synthase
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                  • ADH01490.1
                  • fr9I
                  		 70796 - 79954 (+) type I polyketide synthase
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                    • ADH01491.1
                    • fr9J
                    		 80014 - 80904 (+) malonyl CoA-acyl carrier protein transacylase
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                      • ADH01492.1
                      • fr9K
                      		 80915 - 82204 (+) putative hydroxymethylglutaryl-coenzyme A synthase
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                        • ADH01493.1
                        • fr9L
                        		 82222 - 82977 (+) probable enoyl-CoA hydratase
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                          • ADH01494.1
                          • fr9M
                          		 83053 - 83292 (+) acyl carrier protein
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                            • ADH01495.1
                            • fr9N
                            		 83285 - 84550 (+) beta-ketoacyl synthase
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                              • ADH01496.1
                              • fr9O
                              		 84562 - 85695 (+) malonyl CoA-acyl carrier protein transacylase
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                                • ADH01497.1
                                • fr9P
                                		 86029 - 87054 (+) dioxygenase
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                                  • ADH01498.1
                                  • fr9Q
                                  		 87299 - 87736 (+) hypothetical protein
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                                    • ADH01499.1
                                    • fr9R
                                    		 87831 - 89279 (+) cytochrome P450
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                                      • ADH01500.1
                                      • fr9S
                                      		 89772 - 90230 (+) acetyltransferase
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                                        • ADH01501.1
                                        • fr9T
                                        		 91112 - 92515 (+) diguanylate cyclase
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                                          Biosynthesis information

                                          Biosynthetic modules

                                          Name
                                          Unk01
                                          Type
                                          nrps-type1
                                          Genes
                                          fr9D
                                          Substrates
                                          threonine (evidence: )
                                          Integrated Monomers
                                          Domains
                                          adenylation
                                          Annotation changelog

                                          Entry version: 4

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-10-07
                                          Update chemical activity to schema version 2.11
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 3

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-09-15
                                          Updated bioactivity data
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          2022-09-15
                                          Added NRP substrate specificities
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 2

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2019-10-16
                                          Migrated from v1.4
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          2019-10-16
                                          Updated compound(s) information (NPAtlas curation)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 1

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2015-06-12
                                          Submitted
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          Detailed domain annotation
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