Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000999.1:
Cluster 1NRP / Polyketide120280

BGC0000999, heat-stable antifungal factor biosynthetic gene cluster from Lysobacter enzymogenes. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: heat-stable antifungal factor

Class-specific details

Biosynthetic class(es):
NRP / Polyketide
Polyketide synthase subclass:
Type I

Gene cluster description

heat-stable antifungal factor (BGC0000999). Gene Cluster 1. Biosynthetic class = NRP/Polyketide. GenBank EF028635. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Yu F et al. (2007) Structure and biosynthesis of heat-stable antifungal factor (HSAF), a broad-spectrum antimycotic with a novel mode of action. Antimicrob Agents Chemother 51(1):64-72. doi: 10.1128/AAC.00931-06.