BGC0001002 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001002 (Streptomyces roseoverticillatus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	13,261	liposidomycin B / liposidomycin A / liposidomycin C / liposidomycin Z / liposidomycin H / liposidomycin G / liposidomycin L / liposidomycin M / liposidomycin K / liposidomycin N	Other:Nucleoside	12%

BGC0001002 - Region 1 - T1PKS

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Location: 1 - 13,261 nt. (total: 13,261 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 13,262
Label		BGC0001002

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001002.1	0.45	NRP, Polyketide	jawsamycin	Streptomyces roseoverticillatus
BGC0001858.1	0.25	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001197.1	0.24	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0001909.1	0.23	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001280.1	0.22	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.22	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001444.1	0.22	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0000231.1	0.21	Polyketide	griseusin	Streptomyces griseus
BGC0000888.1	0.21	Other	bacilysin	Bacillus sp. CS93
BGC0000043.1	0.20	Polyketide	curacin A	Moorea producens 19L

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001002.1	0.75	NRP, Polyketide	jawsamycin	Streptomyces roseoverticillatus
BGC0001858.1	0.59	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001197.1	0.57	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0001909.1	0.56	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001280.1	0.55	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.55	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001444.1	0.54	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0000231.1	0.54	Polyketide	griseusin	Streptomyces griseus
BGC0000888.1	0.53	Other	bacilysin	Bacillus sp. CS93
BGC0000043.1	0.53	Polyketide	curacin A	Moorea producens 19L

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 13261:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

jaw4

PKS_AT (568..866): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 70.8%; Propionyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 167.7
inactive: 99.8
Methoxymalonyl-CoA: 96.1
Methylmalonyl-CoA: 85.6
Propionyl-CoA: 56.8
Isobutyryl-CoA: 41.6
Ethylmalonyl-CoA: 40.2
2-Methylbutyryl-CoA: 37.4
fatty_acid: 34.9
CHC-CoA: 30.0
Acetyl-CoA: 29.8
Benzoyl-CoA: 20.1
trans-1,2-CPDA: 17.8
3-Methylbutyryl-CoA: 17.6