LOCUS       BGC0001007             23687 bp    DNA     linear   BCT 28-JAN-2014
DEFINITION  Salinispora arenicola CNS-205, complete genome.
ACCESSION   BGC0001007
VERSION     BGC0001007
KEYWORDS    .
SOURCE      Salinispora arenicola CNS-205
  ORGANISM  Salinispora arenicola CNS-205
            Bacteria; Actinobacteria; Micromonosporales; Micromonosporaceae;
            Salinispora.
COMMENT     URL -- http://www.jgi.doe.gov
            JGI Project ID: 4002390
            Source DNA and bacteria available from Paul Jensen
            (pjensen@ucsd.edu)
            Contacts: Paul Jensen (pjensen@ucsd.edu)
            Paul Richardson (microbes@cuba.jgi-psf.org)
            Quality assurance done by JGI-Stanford
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-PGF
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:38:05
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 23687
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..858
                     /NRPS_PKS="Domain: oMT (41-153). E-value: 9.5e-10. Score:
                     28.9. Matches aSDomain: nrpspksdomains_Sare_3281_oMT.1"
                     /codon_start=1
                     /db_xref="InterPro:IPR000682"
                     /db_xref="InterPro:IPR003333"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR013217"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 95.3; E-value:
                     6.9e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_3281"
                     /note="PFAM: protein-L-isoaspartate(D-aspartate)
                     O-methyltransferase; Cyclopropane-fatty-acyl-phospholipid
                     synthase; Methyltransferase type 11; Methyltransferase type
                     12; KEGG: stp:Strop_3055 methyltransferase type 11"
                     /product="Methyltransferase type 11"
                     /protein_id="ABV99084.1"
                     /sec_met_domain="PCMT (E-value: 6.5e-13, bitscore: 38.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQSNITSRVRDAYDKSADQYESAGQIIFHPLGKMVADLLELKP
                     GERVLDLGCGRGACLFPVAAQVGTDGFVLGIDQAPGMVDACGADIEARGLADRAQVRLG
                     DAQNFTVDQPFDALSAGMVLFLLPEPQQALACAAAALRSGGRLAATTFPTENGRLAAGW
                     ESAEILAEVLSTYLPAGVDDPWRLVLGLNGPLVCEESTAAAVLAAGFTDVEIRHVPARS
                     RFESIDDYLDWTWTVTPRMQWELVPPERRTEATDAARTALRKLAGSDGSLEFSCPTRTI
                     RAVR"
     protocluster    1..23687
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[914:8039]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      915..8039
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     protocluster    1..23687
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[914:8039]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      915..8039
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..23687
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..23687
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001007"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..23687
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..858
                     /locus_tag="Sare_3281"
     aSDomain        124..459
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Sare_3281_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="9.50E-10"
                     /label="Sare_3281_oMT.1"
                     /locus_tag="Sare_3281"
                     /protein_end="153"
                     /protein_start="41"
                     /score="28.9"
                     /tool="antismash"
                     /translation="ELKPGERVLDLGCGRGACLFPVAAQVGTDGFVLGIDQAPGMVDAC
                     GADIEARGLADRAQVRLGDAQNFTVDQPFDALSAGMVLFLLPEPQQALACAAAALRSGG
                     RLAATTFP"
     gene            915..8039
                     /locus_tag="Sare_3282"
     CDS             915..8039
                     /NRPS_PKS="Domain: CAL_domain (33-444). E-value: 9.7e-167.
                     Score: 547.7. Matches aSDomain:
                     nrpspksdomains_Sare_3282_CAL_domain.1"
                     /NRPS_PKS="Domain: ACP (552-624). E-value: 1.9e-27. Score:
                     87.3. Matches aSDomain: nrpspksdomains_Sare_3282_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (649-1073). E-value:
                     6.8e-178. Score: 583.7. Matches aSDomain:
                     nrpspksdomains_Sare_3282_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1180-1473). E-value: 4.2e-109.
                     Score: 356.3. Matches aSDomain:
                     nrpspksdomains_Sare_3282_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DHt (1455-1582). E-value: 1.2e-06.
                     Score: 20.4. Matches aSDomain:
                     nrpspksdomains_Sare_3282_PKS_DHt.1"
                     /NRPS_PKS="Domain: ACP (1591-1661). E-value: 1.3e-27.
                     Score: 87.8. Matches aSDomain:
                     nrpspksdomains_Sare_3282_ACP.2"
                     /NRPS_PKS="Domain: TD (1701-1941). E-value: 5.6e-90. Score:
                     292.6. Matches aSDomain: nrpspksdomains_Sare_3282_TD.1"
                     /codon_start=1
                     /db_xref="InterPro:IPR000182"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002016"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR010080"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR014043"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 292.1; E-value:
                     1.2e-88)"
                     /gene_kind="biosynthetic"
                     /locus_tag="Sare_3282"
                     /note="TIGRFAM: thioester reductase domain; PFAM:
                     GCN5-related N-acetyltransferase; AMP-dependent synthetase
                     and ligase; NAD-dependent epimerase/dehydratase;
                     phosphopantetheine-binding; Male sterility domain;
                     Beta-ketoacyl synthase; Acyl transferase; KEGG:
                     stp:Strop_3056 thioester reductase domain"
                     /product="thioester reductase domain"
                     /protein_id="ABV99085.1"
                     /sec_met_domain="AMP-binding (E-value: 6.3e-111, bitscore:
                     360.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 1.3e-219, bitscore:
                     719.0, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 9.9e-110, bitscore:
                     356.3, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2e-19, bitscore:
                     59.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 7.5e-67, bitscore:
                     214.8, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAELIRPLSELLGQHAVRRGDKIAFADGRRGVSYGDLDRRTARL
                     AGHLAALGLEAGGRAVILMGNSVEAVESCLAVIRAGGVAVPLNPQSSQAEVDYFLDDAE
                     PTVIVCDPARLDQVSRAHSAGRRPPIILAGEAGPGEHGAPDTVRYEDLVGTEPSGPTPD
                     EAPLDDPTWMLYTSGTTGRPKGVLYSLRSSLWLVAACHEPVLGLSEQDRLLWPMPLFHG
                     LGQNLCVIGVTAVGATARLMSGFAPSEVRELLREEAVTFLAGVPTTYHYLLDHVTDGAT
                     DLPALRLGFVAGSASGAALGRRFEEAFGVPLVDQYGSSETGAITSNRPFGDRIPGSVGP
                     PVPGVDIRLVDPDSGRDVPAGEQGEVWVAGPNVMLGYHRQPDATAAVLRDGWYRTGDLA
                     RRDVHGHLTLTGRRKELIIRGGENIHPVEVEEVLRAAAGVSDVAVGAEPHDVLGEVPVA
                     YLVPDPEGVDVATVFAHCRRLLAYHKVPDKLYAIECVPRTTTGKITRHLLAAANPRLLG
                     VATPDSATGETTPVSGDGWTRQLQEMPPSEQTRTVLDLVRTEVARTVGLDAADQIRPDQ
                     PFVDLGLGSLAVVGVGQRLSAQTGLRLPATVVFDHPTPAALASRLVAALTGTSGPAERI
                     HIPDRAGSSNADEPIAIVAMACRFPGGVEDPEQLWTLIADGRDATSDLPQDRNWPLDTL
                     IDPNPDRLGTSYVSRGGFLSDPAGFDAAFFGISPREATAMDPQQRVLLEVAWEAFERAG
                     IDPSRMAGSPTGLFIGTKGQTYSSLAAPASEYEGYLGFATSGSVLSGRVAYTLGLEGPA
                     ITVDTACSASLVALHLACQSLHSGESRLALAGGVTVMATPDDLITFSRQRGLAADGRVK
                     AFAAAADGTAFGEGAGVLLLERLSDARRAGRKVLAVIRGSAINQDGTSNGLTAPNGQAQ
                     QRLIRQALASARLEPADIDLVEAHGTGTALGDPIEAEAILATYGQGRAPEQPVWLGSVK
                     SNITHTQAAAGAAGVIKVVQAMRHGTLPATLNVDQPSPHVDWASGQVRLLTEPRPWQVA
                     GRPRRAGVSAFGISGTNAHVVLEESPVEPPVTANVGRSRAPAAVAWMLSARSPAALRAQ
                     AARLASLARNAPELSPVAVGRALARSRAGLEHRAAIVGADTNQLLRGLDALGSGTPTAG
                     LTTARATPGRAVAVLFTGQGAQYQGMARHLHDSYDVFAEKLDEVCRYLAPEVRQALLAP
                     VDAPDDERIHQTGLTQPALFALEVAQFALLRSWGVVPDVLAGHSIGEITAAHVAGVLSL
                     PDAARLVTARGALMQALPPGGAMLAVKATEEEVLPLVAGEESRVGIAAVNAPRSVVVSG
                     DEDAVASLAATLAEHGHRTRQLKVSHAFHSCRMDPVLDDFRAVAGSLTYHRPTVPIVST
                     VTGAAAGADLITPEYWVGQLRRPVRFASAVESIRAQGADTFVELGPDGVLTALVRETLG
                     ADEHHAVSFSRRGRSGAEITALGALHALGVAVAWEELFPPTGEPEVDLPTYPFQRRRYW
                     LPPALAVPPPAGPEPASHVRVNGAVVAGLGADTARLTSDTQSTGSAESTGSALATRLGA
                     LDEEEQFLHLVQTIKAQVAAVLGHADPDEIDPDESLLDLGFDSLTAVELRNQISDLSGI
                     NLPASLVFEYPTVAVLSDHLLSRVLRAAADGGDDRVDFAAEVTLAADIVCADEVVTAVA
                     EPREVFLTGATGFLGAFLLRDLMHTTNAVVHCLVRSTDDEQARDRLRDNLQWYQLWDEI
                     DPSRLSVVVGDLAAPSFGLSPQRYDDLSRRIDAVYHAAATVNSLYPYSSLKAANVSGTE
                     EVLRLAARHRSVPVHHVSSTGVFSAEVVPGVALTSTDPPGPAEALSSGYRQTKLVAEQI
                     IEIARERGLPVSIYRVDEISGDSEQGRCQTHDFVWLSMKGILQAEAVPADPAGIFHLVP
                     VDYVSSAILRLSRDAAAAGRNHHLANSVHLPFADMMDSLRSLGYRLDELGWDAWVTRVR
                     ANPENTMVAMVDGFESTIYSGRNHYLTVDTSETRALLAGTGIDCPAMTRDLFEKYVDFF
                     VRVGYFPPPGAQEASSAGGRLHIRPATTADLPQLARICYEAFEATNASLGLPPEWPSEQ
                     AVTEMLQGRLTAPSCVSEVAVDAAGSVVGSNFLVLGEEVAAFGPLSVAPDTQGSGVGRM
                     LMESIVAASERLGRPSVRAVQVTNNLRNYRLYSSLGFVPREQLSVMVGFAPPTPRTMAG
                     FEVRPMTEADVTGCQGLYRKINGHSRDSELHMAAKRAFDWSMPYVVLDKTSGELAGYTT
                     GLADLGHLTAVSEAAARALYAGAGALMHRHDAAGPAPRLRIPGRLAPDLLSWAARTRGL
                     SLLRLETLISLGTYTPPEGGVYCPGLSY"
     aSDomain        1014..2246
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Sare_3282_CAL_domain.1"
                     /evalue="9.70E-167"
                     /label="Sare_3282_CAL_domain.1"
                     /locus_tag="Sare_3282"
                     /protein_end="444"
                     /protein_start="33"
                     /score="547.7"
                     /specificity="Minowa: AHBA"
                     /tool="antismash"
                     /translation="SYGDLDRRTARLAGHLAALGLEAGGRAVILMGNSVEAVESCLAVI
                     RAGGVAVPLNPQSSQAEVDYFLDDAEPTVIVCDPARLDQVSRAHSAGRRPPIILAGEAG
                     PGEHGAPDTVRYEDLVGTEPSGPTPDEAPLDDPTWMLYTSGTTGRPKGVLYSLRSSLWL
                     VAACHEPVLGLSEQDRLLWPMPLFHGLGQNLCVIGVTAVGATARLMSGFAPSEVRELLR
                     EEAVTFLAGVPTTYHYLLDHVTDGATDLPALRLGFVAGSASGAALGRRFEEAFGVPLVD
                     QYGSSETGAITSNRPFGDRIPGSVGPPVPGVDIRLVDPDSGRDVPAGEQGEVWVAGPNV
                     MLGYHRQPDATAAVLRDGWYRTGDLARRDVHGHLTLTGRRKELIIRGGENIHPVEVEEV
                     LRAAAGVSDVAV"
     aSModule        1014..2786
                     /domains="nrpspksdomains_Sare_3282_CAL_domain.1"
                     /domains="nrpspksdomains_Sare_3282_ACP.1"
                     /incomplete
                     /locus_tags="Sare_3282"
                     /starter_module
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       1431..1475
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Sare_3282_0001"
                     /evalue="8.90E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="Sare_3282"
                     /protein_end="187"
                     /protein_start="172"
                     /score="18.4"
                     /tool="antismash"
                     /translation="MLYTSGTTGRPKGVL"
     CDS_motif       1989..2072
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Sare_3282_0002"
                     /evalue="1.50E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="Sare_3282"
                     /protein_end="386"
                     /protein_start="358"
                     /score="30.1"
                     /tool="antismash"
                     /translation="PAGEQGEVWVAGPNVMLGYHRQPDATAA"
     aSDomain        2571..2786
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Sare_3282_ACP.1"
                     /evalue="1.90E-27"
                     /label="Sare_3282_ACP.1"
                     /locus_tag="Sare_3282"
                     /protein_end="624"
                     /protein_start="552"
                     /score="87.3"
                     /tool="antismash"
                     /translation="LDLVRTEVARTVGLDAADQIRPDQPFVDLGLGSLAVVGVGQRLSA
                     QTGLRLPATVVFDHPTPAALASRLVAA"
     aSDomain        2862..4133
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Sare_3282_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="6.80E-178"
                     /label="Sare_3282_PKS_KS.1"
                     /locus_tag="Sare_3282"
                     /protein_end="1073"
                     /protein_start="649"
                     /score="583.7"
                     /tool="antismash"
                     /translation="IAIVAMACRFPGGVEDPEQLWTLIADGRDATSDLPQDRNWPLDTL
                     IDPNPDRLGTSYVSRGGFLSDPAGFDAAFFGISPREATAMDPQQRVLLEVAWEAFERAG
                     IDPSRMAGSPTGLFIGTKGQTYSSLAAPASEYEGYLGFATSGSVLSGRVAYTLGLEGPA
                     ITVDTACSASLVALHLACQSLHSGESRLALAGGVTVMATPDDLITFSRQRGLAADGRVK
                     AFAAAADGTAFGEGAGVLLLERLSDARRAGRKVLAVIRGSAINQDGTSNGLTAPNGQAQ
                     QRLIRQALASARLEPADIDLVEAHGTGTALGDPIEAEAILATYGQGRAPEQPVWLGSVK
                     SNITHTQAAAGAAGVIKVVQAMRHGTLPATLNVDQPSPHVDWASGQVRLLTEPRPWQVA
                     GRPRRAGVSAFGISGTNAHVVLEES"
     aSModule        2862..6737
                     /complete
                     /domains="nrpspksdomains_Sare_3282_PKS_KS.1"
                     /domains="nrpspksdomains_Sare_3282_PKS_AT.1"
                     /domains="nrpspksdomains_Sare_3282_PKS_DHt.1"
                     /domains="nrpspksdomains_Sare_3282_ACP.2"
                     /domains="nrpspksdomains_Sare_3282_TD.1"
                     /final_module
                     /locus_tags="Sare_3282"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       3342..3389
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Sare_3282_0003"
                     /evalue="8.10E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="Sare_3282"
                     /protein_end="825"
                     /protein_start="809"
                     /score="17.9"
                     /tool="antismash"
                     /translation="GPAITVDTACSASLVA"
     CDS_motif       3765..3809
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Sare_3282_0004"
                     /evalue="5.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="Sare_3282"
                     /protein_end="965"
                     /protein_start="950"
                     /score="12.2"
                     /tool="antismash"
                     /translation="VEAHGTGTALGDPIE"
     aSDomain        4455..5333
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Sare_3282_PKS_AT.1"
                     /evalue="4.20E-109"
                     /label="Sare_3282_PKS_AT.1"
                     /locus_tag="Sare_3282"
                     /protein_end="1473"
                     /protein_start="1180"
                     /score="356.3"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGAQYQGMARHLHDSYDVFAEKLDEVCRYLAPEVRQALLAP
                     VDAPDDERIHQTGLTQPALFALEVAQFALLRSWGVVPDVLAGHSIGEITAAHVAGVLSL
                     PDAARLVTARGALMQALPPGGAMLAVKATEEEVLPLVAGEESRVGIAAVNAPRSVVVSG
                     DEDAVASLAATLAEHGHRTRQLKVSHAFHSCRMDPVLDDFRAVAGSLTYHRPTVPIVST
                     VTGAAAGADLITPEYWVGQLRRPVRFASAVESIRAQGADTFVELGPDGVLTALVRETLG
                     ADEHHAVSFSRR"
     CDS_motif       4458..4505
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Sare_3282_0005"
                     /evalue="2.40E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="Sare_3282"
                     /protein_end="1197"
                     /protein_start="1181"
                     /score="16.9"
                     /tool="antismash"
                     /translation="FTGQGAQYQGMARHLH"
     CDS_motif       4689..4811
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Sare_3282_0006"
                     /evalue="4.00E-22"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="Sare_3282"
                     /protein_end="1299"
                     /protein_start="1258"
                     /score="70.5"
                     /tool="antismash"
                     /translation="GVVPDVLAGHSIGEITAAHVAGVLSLPDAARLVTARGALMQ"
     CDS_motif       4905..4943
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Sare_3282_0007"
                     /evalue="1.30E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="Sare_3282"
                     /protein_end="1343"
                     /protein_start="1330"
                     /score="12.1"
                     /tool="antismash"
                     /translation="AAVNAPRSVVVSG"
     CDS_motif       5163..5198
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Sare_3282_0008"
                     /evalue="2.40E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="Sare_3282"
                     /protein_end="1428"
                     /protein_start="1416"
                     /score="11.4"
                     /tool="antismash"
                     /translation="YWVGQLRRPVRF"
     aSDomain        5280..5660
                     /aSDomain="PKS_DHt"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Sare_3282_PKS_DHt.1"
                     /evalue="1.20E-06"
                     /label="Sare_3282_PKS_DHt.1"
                     /locus_tag="Sare_3282"
                     /protein_end="1582"
                     /protein_start="1455"
                     /score="20.4"
                     /tool="antismash"
                     /translation="VRETLGADEHHAVSFSRRGRSGAEITALGALHALGVAVAWEELFP
                     PTGEPEVDLPTYPFQRRRYWLPPALAVPPPAGPEPASHVRVNGAVVAGLGADTARLTSD
                     TQSTGSAESTGSALATRLGALDE"
     aSDomain        5688..5897
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Sare_3282_ACP.2"
                     /evalue="1.30E-27"
                     /label="Sare_3282_ACP.2"
                     /locus_tag="Sare_3282"
                     /protein_end="1661"
                     /protein_start="1591"
                     /score="87.8"
                     /tool="antismash"
                     /translation="TIKAQVAAVLGHADPDEIDPDESLLDLGFDSLTAVELRNQISDLS
                     GINLPASLVFEYPTVAVLSDHLLSR"
     aSDomain        6018..6737
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Sare_3282_TD.1"
                     /evalue="5.60E-90"
                     /label="Sare_3282_TD.1"
                     /locus_tag="Sare_3282"
                     /protein_end="1941"
                     /protein_start="1701"
                     /score="292.6"
                     /tool="antismash"
                     /translation="VFLTGATGFLGAFLLRDLMHTTNAVVHCLVRSTDDEQARDRLRDN
                     LQWYQLWDEIDPSRLSVVVGDLAAPSFGLSPQRYDDLSRRIDAVYHAAATVNSLYPYSS
                     LKAANVSGTEEVLRLAARHRSVPVHHVSSTGVFSAEVVPGVALTSTDPPGPAEALSSGY
                     RQTKLVAEQIIEIARERGLPVSIYRVDEISGDSEQGRCQTHDFVWLSMKGILQAEAVPA
                     DPAGIFHLVPVDYVSSAI"
     gene            complement(8219..10180)
                     /locus_tag="Sare_3283"
     CDS             complement(8219..10180)
                     /EC_number="6.3.5.4"
                     /codon_start=1
                     /db_xref="InterPro:IPR000583"
                     /db_xref="InterPro:IPR001962"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR006426"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 632.2; E-value: 1.5e-191)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_3283"
                     /note="KEGG: stp:Strop_3057 asparagine synthase
                     (glutamine-hydrolyzing); TIGRFAM: asparagine synthase
                     (glutamine-hydrolyzing); PFAM: glutamine amidotransferase
                     class-II; asparagine synthase"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="ABV99086.1"
                     /sec_met_domain="GATase_7 (E-value: 2.9e-43, bitscore:
                     136.5, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 2.2e-100, bitscore:
                     326.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLLAFFSARGDAAAHRDHIAGALECLHHRGPDETGVEVVGDAS
                     GQYADGVFAHKRLAIIDVASSHEPLPYAGGRYLLTFNGEIYNYIELREELARDYGAQFA
                     TSGDGEVIVAGYHYWGEQVLSRLRGMFAFVIWDRQERRAFGARDYFGIKPLHYLETADG
                     LYLASEKKALLPFAPANYHGDAGIDTASLSHYLTLQYVPEPGTLHQGIRRIGSGEYLTW
                     TPGGRIDVRRWYRPVFRPAPVSDEQKLYHEIRERLRDSVRIHMRSDVPVGSFLSSGIDS
                     TAVVALAREFNPNILTFTVGYDVPGYSEIDVAQESARHLDVTTIPTKIGPQDMMAALPK
                     IVWHLDDPVADPALVPLYFVARKAAEHVTVVLSGEGADEFFGGYTIYREPLSLSTVNGL
                     PGGVQKGLRAVSKAIPQGVKGKSFLERGTTPIEARYYGNARMFTEEEKQHLLRRYDPSV
                     RYTDITAPIYAECTELDDVTKMQYVDLYTWLRGDILVKADRISMAHSLEVRVPFLDREV
                     FDVASKIPVDLKLPPRSDATKYAMRQALQGVVPPAIVNRRKLGFPTPTRVWLRGEMYEW
                     ARHMLATSGAGDLIDLSYALRLLDEHKREEADHSRKVWTVLIFCIWHAIFVAKTLDPGI
                     QRNQSALLTKPVVGSMVR"
     gene            10300..11778
                     /locus_tag="Sare_3284"
     CDS             10300..11778
                     /EC_number="3.4.11.9"
                     /codon_start=1
                     /db_xref="InterPro:IPR000994"
                     /db_xref="InterPro:IPR007865"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172:methionine aminopeptidase (Score: 311.8; E-value:
                     1.1e-94)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_3284"
                     /note="PFAM: peptidase M24; peptidase M24B X-Pro
                     dipeptidase/aminopeptidase domain protein; KEGG:
                     stp:Strop_3058 Xaa-Pro aminopeptidase"
                     /product="Xaa-Pro aminopeptidase"
                     /protein_id="ABV99087.1"
                     /transl_table=11
                     /translation="MTEERVNRSPEGTESHDPAFPQALLAFMRQGWRDTALPVSPRPEV
                     PNYAKRRAALSAAFPGETLVIPTGGEKTRANDTAFRFRPGTDFAYLTGDHAPDSVLVLH
                     PTASGHEPVLYLRPHSSRQTDEFFRSRHGELWLGRRHTLAEKATELGLATADLDELDAA
                     LAGLAPARTRVLRGFDAQVDAAIRSYDEQRERGQPARDRELAIAISELRLVKDEWEIAQ
                     LQDAVDATVRGFEDVARALPADRGVSERLLEGIFALRARHDGNDVGYGSILGAGEHATI
                     LHWVHNHGSTRPGELLLMDMGVENHHLYTADVTRVLPVSGRFTALQRQVYDIVYASQQA
                     GIEFIRPGVAFKDVHLTCMRVLAEGLADLGLLPVSVDEAMDEKSAVYRRWTLHGFGHML
                     GIDVHDCTNARAEMYRDGTLGEGYVLTVEPGLYFQPEDELVPEELRGIGVRIEDDVLVT
                     ATGTVNLSAGLPRTAGDVETWLAEQREAGPRLPG"
     gene            12055..13653
                     /locus_tag="Sare_3285"
     CDS             12055..13653
                     /codon_start=1
                     /locus_tag="Sare_3285"
                     /note="KEGG: stp:Strop_3059 hypothetical protein"
                     /product="conserved hypothetical protein"
                     /protein_id="ABV99088.1"
                     /transl_table=11
                     /translation="MSIDVTTPDGGANAGPPKRGRRALWVAAGVVGLTGVVGLAALGGA
                     VTRDDKTAGSAGQTEATEAQANARQNVGDAGPTKAGTTNDSQGEGTWSGGDQSGRDDHR
                     SPARRTKNIPCNSDKLIQAIVHANQNRGGELTLAKGCTYELTRSVHGNGLPVIKEPIVL
                     KGYDTTIVRAANAEHFRIFNVGRDGHLTLQGVTVKGGQTTPRWDHYPTLEAAPPLTLSA
                     QDGVTRATKPTVAGSTAAGAVGRHGDGAGILVQRGGEANIQDSSVVLNHGRNGGGIANY
                     GTTTIRKSSVEHNSATGFGGGVFNVGVLRIEWAKIEQNNARLGGGGFANGSLGFGDKGG
                     TVWVWRSTISHNQTLGLAGGILDRSGDTSVTRSEVTENTAGRDAGGVLGVDGSRLYLEE
                     VMIERNVATGVAGGLAVADDATAILEKSVLEENVAEGVGGAGLFNAQAYVTLRDSKIVG
                     NRAIGPFAVGGGIVNAFGQVSLIRSTVTGNFATTPPGGIFTTNDGVEIDEKSAVKKNRP
                     TNCTGSPVIPERCFG"
     gene            14002..16524
                     /locus_tag="Sare_3286"
     CDS             14002..16524
                     /codon_start=1
                     /db_xref="InterPro:IPR003368"
                     /locus_tag="Sare_3286"
                     /note="KEGG: stp:Strop_3060 hypothetical protein"
                     /product="hypothetical protein"
                     /protein_id="ABV99089.1"
                     /transl_table=11
                     /translation="MSNYQAQNNAIDPEAASKRRRKLWLASGVAGLTGVVSIAAVGFTG
                     AGAGARDLAWNTAQITKNGEQVADDPGAGRVGGWEANHRGDSDGNRDDRNRGKKKRGKE
                     VPCNTDQLIQAIVYANSNQGGVLKLAKDCTYTLTRSDKHGNGLPIIKEPITLAGYNTKI
                     VRDSQADFFRILNVGRGGHLKVEGLTIKGGKTLEGERGANTPEAVWSRFSNSVAAGEAA
                     KAGKPFLPLLQAEPGAAARGTDAARAAEGAPAGRVAAATDAAPAPVWNDRAPAGRSATE
                     GAPAIDAAPAAGWTDRAPAADKAPAAEGAPADRLAPATDAAPAPVWTDRAPAADKAPAG
                     GWGDKAPAAEGAPADRRAPAADKAPATDAAPAPVWTDRAPAADKAPAGGWGDKAPAAEG
                     APADRRAPAADKAPATDAAPAPVWTDRAPAADKAPAGGWGDKAPAAEGAPADRRAPAAE
                     QAPATDAAPAPVWTDRAPAADKAPAGGWGDKAPAAEGAPADRRAPAAEQAPATDAAPAP
                     VWTDRAPAADKAPAGGWGDKAPAAKKEKPKVLRHDRSSDGAGVLVQAGGTAEFEKSYLE
                     HNLAGGVGGGLANFGKTSLYHTTVANNDAFHYGGGIFNAGVLRVSSSRVMDNGAAIGGG
                     GIANGAAFVDRKDIEPGYVTVEKAEVTGNEVLGFGGGLFDIGGETTVKQSIVARNLALL
                     AGGGIAAVEGSNLYLKEMEVADNTTIGDGGGLALALGAIANVDKSKVRDNKAGVFGGGV
                     FNLLSAVTFRNSSVSGNLAGISGGGIFNVAGSVDLTATKVTKNRSTLEPGGVFSALGKV
                     TVDNKSAVKGNDPTNCKGSVDRIENCFG"
     gene            complement(16708..17301)
                     /locus_tag="Sare_3287"
     CDS             complement(16708..17301)
                     /codon_start=1
                     /locus_tag="Sare_3287"
                     /note="KEGG: pac:PPA1515 hypothetical protein"
                     /product="conserved hypothetical protein"
                     /protein_id="ABV99090.1"
                     /transl_table=11
                     /translation="MTNRLGFWLAHLFVLSYCGVLLAAFGVQFVTGELPCPLCILQRMA
                     MMLVVCGPLYIIGRARRGDVTLADYAMGYGLSIVAAVAGAAYAARQILLHIVPPDPGYG
                     SPVLGLHPYTWAFITFCVVLVFCGVSLVFGRELVPRGVRFGWPSKVVIGLFLVIVAANL
                     VAVFVQEGFHWFLPADPTRYEIFDDLSLVGDARG"
     gene            complement(17317..17475)
                     /locus_tag="Sare_3288"
     CDS             complement(17317..17475)
                     /codon_start=1
                     /locus_tag="Sare_3288"
                     /product="hypothetical protein"
                     /protein_id="ABV99091.1"
                     /transl_table=11
                     /translation="MDTLIFAVILLSVWLTARGSRRRTVLAVWTVALCATLLLFIHHSA
                     TKLPLNF"
     gene            17770..20616
                     /locus_tag="Sare_3289"
     CDS             17770..20616
                     /codon_start=1
                     /db_xref="InterPro:IPR000573"
                     /db_xref="InterPro:IPR001030"
                     /db_xref="InterPro:IPR006249"
                     /locus_tag="Sare_3289"
                     /note="TIGRFAM: aconitate hydratase 1; PFAM: aconitate
                     hydratase domain protein; KEGG: stp:Strop_3062 aconitate
                     hydratase 1"
                     /product="aconitate hydratase 1"
                     /protein_id="ABV99092.1"
                     /transl_table=11
                     /translation="MASLDTFGAKTQLRVGDASYEIFKINKVKGHERLPYSLKILLENL
                     LRTEDGANITADHIRQLGAWEPTADPSVEIQFTPARVLMQDFTGVPCVVDLATMREAVR
                     DLGGDPTKVNPLAPAELVIDHSVIADLFGREDAFQRNVELEYERNKERYQFLRWGQTAF
                     NEFKVVPPGTGIVHQVNIEYLARTVMERNGQAYPDTVVGTDSHTTMVNGLGVVGWGVGG
                     IEAEAAMLGQPVSMLIPRVVGFKLSGEMPAGTTATDLVLTITEMLRRHGVVGKFVEFYG
                     PGVSAVPLANRATIGNMSPEYGSTVAIFPIDAETVRYLELTGRDPQQVALVEAYAKEQG
                     LWHDPSAEPDYSERLELDLGSIEPSLAGPKRPQDRVPLGNAKTLFRAALTDYVATDETG
                     GDLGRGQEHGVTGHADEASAESFPASDAPANEITDPADAPRDLVTAAVGAGGRATSPIR
                     VTGADGTEFELDHGAVVIAAITSCTNTSNPQVMIGAALLARNAVERGLARKPWVKTTLA
                     PGSKVVMDYYERAGLTPYLEKLGFHLVGYGCTTCIGNSGPLPEEISAAVNEKDLAVVSV
                     LSGNRNFEGRINPDVKMNYLASPPLVVAYALAGTMDIDLANEPIGEDAQGTPVFLRDIW
                     PSSTEIQDVIASAIGAGGFSSAYADVFAGDERWRSLPTPTGDTFAWEGESTYVRKPPYF
                     EGMRREPAPVSDIAAARVLAKLGDSVTTDHISPAGAIKPDSPAGRYLAEHDVPRHEFNS
                     YGSRRGNHEVMIRGTFANIRLRNQLRVPSAGSAAGVALPEGGFTVNHLTGEQSTIYDAA
                     VAYQETGIPLIVLAGKEYGSGSSRDWAAKGTMLLGVKAVIAESYERIHRSNLIGMGVLP
                     LQFPVGETAESLGLTGTESFSVTGVTALNGGDTPRTVRVTTDTGIEFDAVVRIDTPGEA
                     DYFRHGGILQYVLRRMIG"
     gene            20803..21051
                     /locus_tag="Sare_3290"
     CDS             20803..21051
                     /codon_start=1
                     /locus_tag="Sare_3290"
                     /note="KEGG: stp:Strop_3063 hypothetical protein"
                     /product="conserved hypothetical protein"
                     /protein_id="ABV99093.1"
                     /transl_table=11
                     /translation="MDDKTILKRISELVDEEHRLRTEAQANEEGTDEESRNRLRDLAES
                     LDQCWDLLRRRRAARTTHGDPDAQGVRPAPEVARYLQ"
     gene            complement(21188..22114)
                     /locus_tag="Sare_3291"
     CDS             complement(21188..22114)
                     /codon_start=1
                     /db_xref="InterPro:IPR000687"
                     /locus_tag="Sare_3291"
                     /note="PFAM: protein of unknown function RIO1; KEGG:
                     stp:Strop_3064 protein of unknown function RIO1"
                     /product="protein of unknown function RIO1"
                     /protein_id="ABV99094.1"
                     /transl_table=11
                     /translation="MRDHDFPAPERRTRGRRRFDDDEPHLAKRGRKAEPQPVDLDPLPD
                     AGTWSSWDDAVHGPRPYPAWLVTELAARDTELGVLKTGKEADVHLVRRAVPDTDRSCLL
                     AAKRYRDADHRLFHRDAGYLEGRRVRRSREMRAMTRRTAFGRQMIAGQWAAAEFAVLGR
                     LWEIGARYGTITVPYPVQLRGTELMLEFLGDPDEGLAAPRLAQLRPGEADLRDLWGQLV
                     EALMVLARAGHAHGDLSPYNLLVHEGRLVLIDLPQVVDLVANPQGPEFLARDVRVVATW
                     FAARGLPAALADPLALTEQLLREAGLR"
     gene            complement(22268..22912)
                     /locus_tag="Sare_3292"
     CDS             complement(22268..22912)
                     /codon_start=1
                     /db_xref="InterPro:IPR005834"
                     /db_xref="InterPro:IPR006439"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 55.5; E-value: 1.1e-16)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_3292"
                     /note="TIGRFAM: HAD-superfamily hydrolase, subfamily IA,
                     variant 1; PFAM: Haloacid dehalogenase domain protein
                     hydrolase; KEGG: stp:Strop_3065 HAD-superfamily hydrolase,
                     subfamily IA, variant 1"
                     /product="HAD-superfamily hydrolase, subfamily IA, variant
                     1"
                     /protein_id="ABV99095.1"
                     /transl_table=11
                     /translation="MPLLLLDLDNTLLDRENLFRSWAERFLVKVGAPPGDLDWLLAVDG
                     DGLTDRWDVADAIRNRYALSVRSVDLVEELHDGTLADTRLDPLVACALRIAGEVGWMPV
                     VVCNGAVRQQEGKIRRTGLDRYIADWVISEEVGVSKPNPRIFALAAQRVRMPLRGAWVV
                     GDGPEADIGGAAAAGLPSVWLHRGRTWNDSRFAPTYTADGPIAAVAAVLAA"
     gene            23115..23687
                     /locus_tag="Sare_3293"
     CDS             23115..23687
                     /codon_start=1
                     /db_xref="InterPro:IPR001647"
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 82; E-value: 1.2e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="Sare_3293"
                     /note="PFAM: regulatory protein TetR; KEGG: stp:Strop_3066
                     transcriptional regulator, TetR family"
                     /product="transcriptional regulator, TetR family"
                     /protein_id="ABV99096.1"
                     /transl_table=11
                     /translation="MPRVSQDQLDARRQEILTAARVCFARHGYEGATVRRLEEATGLSR
                     GAIFHHFRDKDSLFLAVAEDDAAAMVETVARNGLVQVMRDLLARAVSPDTTGWLGSQLE
                     VSRRLRTDPAFARRWAERSAAIAEATRDRLRRQREAGVLRDDVSIDVLAQFLELAYDGL
                     VLHLAMGRPAGDLGPVLNLVEEAVRRR"
ORIGIN
        1 atgaccgagc agtccaacat cacctcgcgt gttcgggacg cctacgacaa gtctgctgat
       61 cagtacgagt cggccggcca gatcatcttc cacccactgg gcaagatggt tgccgacctg
      121 ctggagctca agccgggcga gcgggtgctc gacctcggct gcggccgagg cgcctgcctg
      181 tttcccgtcg ccgcccaggt tggcaccgac ggcttcgtgc tcggcatcga ccaggcaccc
      241 ggcatggtgg acgcgtgcgg ggccgacatc gaggcccgcg gactggccga ccgcgcgcag
      301 gtcaggttgg gtgacgccca gaacttcacc gtcgaccagc ccttcgacgc gctgagcgcc
      361 ggcatggtcc tgttcctgct gccagagccg cagcaggcgt tggcgtgcgc cgcggcggcg
      421 ctgcgcagcg gtgggcggtt ggccgcgacg accttcccca cggagaacgg ccgacttgcc
      481 gcgggctggg agtcggcgga gatcctcgcc gaggtgctgt ccacgtatct cccggcgggt
      541 gtcgacgatc cgtggcggct cgtcctcggt ctcaacggac cgctggtctg cgaggagtcg
      601 acggccgccg cggtcctggc cgccggcttc accgacgtcg agattcgtca cgtaccagcg
      661 aggtcccggt tcgagtcgat cgatgactac ctggactgga cctggacggt caccccgcgc
      721 atgcagtggg aactggtgcc gccggagcgg cgcaccgagg caaccgacgc ggcccgtacc
      781 gcactgcgga aactggcggg ctccgacggt tcgctggagt tctcctgccc gaccagaacg
      841 atccgcgccg tgcgctgagt ggcgccgccc gccaacaccg actaccccag tacgaagccg
      901 aaaggtacga agtcatgcgt gcagagttga tccggccgct gtccgagctg ctcggccaac
      961 acgccgtccg acgcggggac aagatcgcct tcgccgacgg aaggcgtggc gtcagctatg
     1021 gcgacctgga tcgacggacc gcccgactgg ccgggcacct ggccgcgttg gggttggaag
     1081 ccggtgggcg ggccgtgatc ctgatgggta acagcgtcga ggcggtggag agctgcctcg
     1141 cggtgatccg ggccggtggt gtcgcggtgc cactcaaccc acagtcctcc caggccgagg
     1201 tcgactactt cctcgacgac gccgagccga cggtcatcgt gtgcgacccg gcccgactcg
     1261 accaggtgag ccgggcccac tccgccggtc ggcgaccacc gatcattctc gccggcgagg
     1321 ccggacccgg ggagcacggt gcacccgaca cggtgcgata cgaggatctg gtgggcaccg
     1381 agccgagcgg gccgaccccc gacgaggcac cgctggacga cccgacgtgg atgctctaca
     1441 cgtcggggac caccggccgg ccgaagggtg tgctgtactc gcttcgcagc tcgctgtggc
     1501 tggtcgctgc ctgtcacgag ccggtgctgg gcctgtccga gcaggaccgt ctgttgtggc
     1561 ccatgccgct gttccacggg ctcgggcaga acctgtgcgt gatcggggtg accgcggtcg
     1621 gcgcaactgc ccggctgatg agcggcttcg ccccgtcgga ggtgcgtgag ctcctgcgcg
     1681 aggaggccgt cacatttctg gctggggtgc caaccaccta ccactatttg ttggaccacg
     1741 tcaccgacgg cgccacggat ctccccgcgc tgcggctggg cttcgtggcg ggatcggcga
     1801 gtggtgcggc gctgggcagg cggttcgagg aggcgttcgg tgtgccgctg gtggaccagt
     1861 acggttcctc cgagaccggt gcgatcacct cgaaccggcc gttcggagac cgaatccccg
     1921 gctccgtggg gccgccggta ccaggcgtgg acatccgcct ggtcgacccc gattcgggcc
     1981 gggacgtacc tgcaggggaa cagggcgagg tgtgggtcgc cggccccaac gtcatgctgg
     2041 gatatcaccg gcagcccgat gccaccgccg cggttctccg cgatggctgg taccgcacag
     2101 gtgacctggc acgacgcgat gtccatgggc acctgaccct gaccggtcgg cgcaaggaac
     2161 tgatcatccg tggtggcgag aacatccacc cggtcgaggt cgaggaagtg ctgcgcgccg
     2221 ccgccggggt gtccgacgtg gcggtgggcg ccgagccaca cgacgtgctc ggtgaggtgc
     2281 cggtggccta tctggtgccg gatccggaag gcgtggacgt ggcaacggtc ttcgcgcact
     2341 gccggcggct gctggcgtac cacaaggtgc ccgacaagct ctacgccatc gagtgcgttc
     2401 cccgaaccac caccggcaag atcacccggc acctcctggc agcggcgaac ccacggctgc
     2461 tgggcgtggc caccccggac agcgcaaccg gtgagaccac gccggtgtcg ggcgacgggt
     2521 ggacccggca gttgcaggag atgcccccga gcgagcagac ccggaccgtc ctggatctgg
     2581 ttcgtaccga ggtggcacgg accgtcggtc tggacgccgc cgaccagatc aggcccgatc
     2641 agccgttcgt cgacctcggg ctcggttcgc tggccgtcgt cggggtcggc cagcgactca
     2701 gtgcgcagac cgggctacgg ctcccagcga ccgtcgtgtt cgaccatccg acacccgcgg
     2761 ccctcgcgtc caggctggtc gccgcactga ccgggacgag cggcccagcc gaacgcattc
     2821 acattccgga ccgggccggc tcgtccaacg ccgacgagcc gatcgcgatc gtcgcgatgg
     2881 cctgccgatt ccccggcgga gtcgaggatc cagagcaact gtggacgctg atcgccgacg
     2941 ggcgggacgc tacctcggac ctcccgcagg accggaactg gccgctggac acgctcatcg
     3001 acccgaaccc ggaccggctc ggcaccagct acgtgtcccg gggcgggttc ctgtccgacc
     3061 ccgccggctt cgacgccgct ttcttcggga tcagcccccg ggaggcgacc gcgatggacc
     3121 cgcagcagcg ggtactcctg gaagtcgcgt gggaggcgtt cgaacgggcc ggtatcgacc
     3181 cgagccggat ggccggttcg ccgaccggcc tcttcatcgg cacgaagggg cagacataca
     3241 gttccctcgc cgcgccggcc tcggagtacg agggctacct gggcttcgcc acctcgggca
     3301 gcgtgctgtc cggacgcgtc gcctacaccc tcgggctgga aggcccggcc atcaccgtgg
     3361 acaccgcctg ctcggcttcg ttggtggcac ttcacctggc gtgtcagtcc ctgcactccg
     3421 gggagtcccg gctcgccctc gccggtggtg tcacggtgat ggccaccccg gacgacctga
     3481 tcacgttcag caggcagcgc ggtctcgcgg cggacggccg ggtcaaggcg ttcgccgcgg
     3541 cggccgacgg caccgccttc ggcgagggcg ccggtgtcct gctgctggaa cggctctcgg
     3601 acgcacgccg ggctggacgc aaggtgctcg ccgtcatccg gggcagcgcg atcaaccagg
     3661 acggcacgtc gaacgggctc accgccccca acggccaggc acaacagcgg ctgatccgcc
     3721 aggccctcgc ctccgcccgg ctcgaacccg ccgacatcga cctggtcgag gcgcatggca
     3781 ccggaacggc tctcggtgac ccgatcgaag ccgaggcgat tctcgccacc tacgggcagg
     3841 ggcgtgcgcc cgagcagccg gtgtggctcg gatccgtcaa gtccaacatc acccacaccc
     3901 aggctgctgc cggtgccgcc ggcgtcatca aggtcgtgca ggcgatgcgc catggaaccc
     3961 tcccggccac gctcaacgtc gaccaaccgt ctccgcatgt cgactgggcc tccgggcagg
     4021 tacgcctact gaccgagccc cgaccgtggc aggtagccgg ccgcccccga cgtgccgggg
     4081 tttccgcgtt cggcatcagc ggcaccaatg cccacgtggt cctggaggag agcccggtgg
     4141 agccgccggt cacggcgaac gtcggccggt cccgggcacc cgccgcggtt gcctggatgc
     4201 tgtctgcccg ctcgccggcg gcgctccggg cgcaggccgc ccggctggcc tcgctggcgc
     4261 ggaacgcgcc ggagctcagc ccggtcgccg tgggccgcgc tctggctcgt tcgcgcgcgg
     4321 gcctggaaca ccgggcggcc atcgtgggtg ccgacacgaa ccagctgctg cgtggtctgg
     4381 atgccctcgg ttcgggtacg ccgacggccg ggctgaccac ggcgcgcgcg acacccggcc
     4441 gggccgtggc ggttctcttc accgggcagg gcgcgcagta ccagggcatg gcccgccacc
     4501 tccacgacag ctacgacgtg ttcgccgaga aactggacga ggtgtgccga tatctggctc
     4561 cggaggtacg gcaggccctg ctggcgcccg tggacgcgcc ggacgacgaa cggatccacc
     4621 aaaccggtct cactcagccc gccctgttcg ccttggaggt cgcacagttt gccctcctgc
     4681 gctcctgggg ggtggtcccc gacgtccttg ctgggcactc catcggtgag atcaccgcag
     4741 cgcatgtggc tggggtgctc tcactgccgg acgcggcccg tctggtcacc gcccgtggcg
     4801 ccctgatgca ggcgctgccc ccgggtgggg cgatgctcgc ggtcaaggcc acggaggagg
     4861 aggtgctgcc cctggtcgcc ggggaggagt cgcgcgtggg aatcgccgcg gtcaacgcac
     4921 cccggtcggt cgtcgtctcg ggcgacgagg acgccgtggc ctcgctcgcc gcgacgctgg
     4981 ccgagcacgg gcaccgcacc aggcagctca aggtgagcca tgctttccac tcgtgtcgca
     5041 tggaccctgt cctcgacgac ttccgcgccg tcgcggggtc gctgacctac caccggccaa
     5101 ccgttccgat cgtctccacc gtgaccggcg cggccgccgg tgcggacctg atcacgccgg
     5161 agtactgggt cgggcaactc cgccggccgg ttcgtttcgc gtcggcggtg gaatcgattc
     5221 gagcacaggg cgccgacacc ttcgtcgagc tcgggcccga cggggtactg acggcattgg
     5281 tgcgggaaac cctcggtgcg gacgagcacc acgcggtgtc gttcagccgc cgtggacggt
     5341 cgggcgccga gatcaccgcc ctgggagccc tgcacgctct tggtgtcgcc gtggcgtggg
     5401 aggagctctt cccaccgacc ggggaacccg aggtcgacct gcccacctac ccgttccagc
     5461 gacggcgcta ctggctccca ccagcccttg ccgtgccgcc gcccgcgggc ccggagccgg
     5521 ccagccacgt acgggtcaac ggggcggtcg tggccgggct gggagccgac accgcgcggt
     5581 tgaccagcga cacgcagtcg accggcagcg cggagtcgac cggcagcgcg ctggcgaccc
     5641 gactcggcgc cctcgacgag gaggaacagt tcctgcacct ggtgcagacc atcaaggccc
     5701 aggtcgccgc cgtgctcggg cacgccgacc cggacgagat cgatcccgac gagtccctgc
     5761 tggacctggg cttcgactcc ctcaccgcgg ttgagctgcg caaccagatc agcgacctca
     5821 gcgggatcaa cctccccgcc tcactggtct tcgagtatcc caccgtggcg gtcctctccg
     5881 atcacctgct gagcagggtg ctccgcgcgg cagctgacgg tggcgacgac cgggtggact
     5941 ttgccgccga ggtgaccctg gccgccgaca tcgtctgcgc ggacgaggtc gtcacggctg
     6001 tcgcggagcc ccgggaggtc ttcctcaccg gagcgaccgg cttcctcggc gccttcctgc
     6061 tccgcgacct gatgcacacc acgaacgccg tcgtgcactg cctcgtccgc tccaccgacg
     6121 acgaacaggc acgtgaccgg ctacgggaca acctccagtg gtaccagctc tgggacgaga
     6181 tcgacccgag ccggttgtcc gtggtggtcg gcgacctggc cgccccttcg ttcggcctgt
     6241 cgccgcagcg gtacgacgac ctctcccgca gaatcgacgc ggtctaccac gcggctgcca
     6301 ccgtcaacag tctctacccc tactcctcgc tgaaggcggc gaacgtgtcc ggcaccgagg
     6361 aggtgctccg gcttgccgca cggcaccgca gcgtgccggt ccaccacgtg tcgtccacgg
     6421 gtgtcttctc cgctgaggtg gtgcccggag tcgccctgac gtcgactgat ccgcccgggc
     6481 ccgccgaggc gttgtcctcc gggtaccgac agaccaagct ggtcgcggag cagatcatcg
     6541 agatcgcccg ggagcgtggg ctcccggtgt cgatctaccg ggtcgatgag atctccggcg
     6601 actcggagca gggccgttgc cagacgcacg acttcgtgtg gttgagcatg aagggcattc
     6661 tccaggcaga ggccgttccg gcggaccctg ccggcatctt ccacctggtt cccgtcgact
     6721 atgtcagctc ggcgatcctg cggctgtccc gggacgcggc cgccgccggc cgcaaccacc
     6781 acctcgccaa cagcgtgcat ctgccgttcg ccgacatgat ggactcactg cgctcgctcg
     6841 gctatcgact cgacgagttg ggctgggacg cctgggtcac gcgggtgcgc gccaaccccg
     6901 aaaacaccat ggtggcgatg gtcgacggct tcgagtccac catctacagc ggacgcaatc
     6961 actacctgac ggtcgacacg tccgagacgc gcgcgttgct ggccggcacc ggcatcgact
     7021 gtccggccat gacccgggac ctgttcgaga agtacgtcga cttcttcgtc cgggtgggct
     7081 acttcccacc gcccggtgcg caggaggcga gctccgcggg tggtcgcctc cacatccggc
     7141 cggcaaccac cgccgacctg ccacaactgg cccggatctg ctacgaggcg ttcgaggcca
     7201 ccaacgcgtc gttgggtcta ccccccgagt ggccctcgga acaggcggtg acggagatgc
     7261 tccagggacg actcaccgca ccgagttgcg tgagcgaggt ggcggtcgac gcggctgggt
     7321 cggtggtggg ctccaacttc ctggtactgg gtgaggaggt agccgccttc ggaccgctga
     7381 gcgtggcccc cgacacgcag ggaagtgggg tgggacggat gctgatggag tcgatcgtcg
     7441 ccgccagcga acggctcggc cggccgtccg ttcgcgccgt ccaggtcacc aacaacctcc
     7501 ggaactaccg gctgtactcg tcgctcggtt tcgtgcctcg ggaacaactc tctgtgatgg
     7561 tcggcttcgc cccaccgact ccccgcacca tggcggggtt cgaggtacgt cccatgactg
     7621 aggcggatgt taccggctgt cagggcctgt accgcaagat caatggccat tcccgggaca
     7681 gtgagctcca catggcggca aagcgggcgt tcgactggtc gatgccgtac gtggtgctgg
     7741 acaagacgag cggcgagctc gccggctaca ccaccggact ggccgacctg ggacacctga
     7801 ccgccgtttc ggaggcggcg gcgcgtgcgc tgtatgccgg cgccggtgcg ctgatgcatc
     7861 gccatgacgc cgccggcccg gcaccccggc tgcgcatccc tggccgcctg gcaccggacc
     7921 tgctcagctg ggcagcccga acccggggac tctcgctact ccgactggag acgctgatct
     7981 cgctgggcac ctacacccca ccggagggcg gggtgtactg cccggggctg tcctactgat
     8041 cgcccgggcc gcggaggttg tgctggttag gacacacgca acgcaccgat gggtgtcgtg
     8101 ggatgccagg gccgaaaccg ggttgaggga gcccgatcgg cccggagggg ggagcgtcgg
     8161 ggcggctcgt ggagccaccc cgacgcgcat cccgacgatg gcctggcccg gtgcccgctc
     8221 agcgcaccat gctgccgacc accggcttcg tcagcagggc cgactggttg cgctggatcc
     8281 ccgggtcgag ggtcttggca acgaagatcg catgccagat gcagaagatc agcacggtcc
     8341 ataccttgcg ggagtggtcg gcctcctccc gcttgtgctc atcgagcagc cgcagcgcgt
     8401 acgacaggtc gatcaggtca ccggcaccgg aggtggccag catgtgccgg gcccactcgt
     8461 acatctcacc ccgcagccac acccgagtcg gggtcgggaa gcccagcttc cggcggttga
     8521 cgatggccgg aggcaccacc ccctgcaacg cctggcgcat ggcgtacttg gtggcgtcgg
     8581 agcgcggggg cagcttgagg tcgaccggga tcttcgacgc cacgtcgaag acctcccggt
     8641 cgaggaacgg cacccgcacc tccagcgagt gcgccatcga gatccggtcg gccttgacca
     8701 ggatgtcgcc ccgcagccag gtgtagaggt ccacgtactg catcttggtg acgtcgtcga
     8761 gttcggtgca ctcggcgtag atcggggcgg tgatgtcggt gtagcgcacc gacgggtcgt
     8821 agcggcgcag caggtgctgt ttctcctcct cggtgaacat tcgggcgttg ccgtagtaac
     8881 gcgcctcgat gggagtggtg ccgcgctcca ggaagctctt gcccttgacc ccctgcggga
     8941 tcgccttcga gaccgcccgc agccccttct gcacaccgcc gggaagtccg ttgaccgtgc
     9001 tcagcgacag tggctcccgg tagatcgtgt acccgccgaa gaactcgtcg gcgccctcgc
     9061 cggagagcac caccgtgacg tgttcggcgg ccttacgcgc cacgaagtag agcggcacca
     9121 gcgccgggtc ggcgaccggg tcgtccaggt gccagacgat cttcggcagc gccgccatca
     9181 tgtcctgcgg cccgatcttg gtgggaatgg tggtgacgtc caggtggcgg gccgactcct
     9241 gggctacgtc gatctccgag tagccgggca cgtcgtagcc gaccgtgaag gtcagaatgt
     9301 tcgggttgaa ctcccgggcc agggccacca cggcggtgga gtcgatcccg ctggacagga
     9361 acgaaccgac cgggacatcc gagcgcatgt gaatccggac gctgtcccgc agtctctccc
     9421 ggatctcgtg gtagagcttc tgctcgtccg acaccggggc gggtcggaac accggccgat
     9481 accagcgacg gacatcgatc cggccaccgg gagtccaggt caggtactcc cccgagccga
     9541 tacgacggat cccctggtgc agggtgccgg gctccggcac atactgcaag gtcaggtagt
     9601 ggctgaggct ggccgtgtcg atgccggcgt cgccgtggta gttggccggc gcgaacggca
     9661 acagcgcctt cttttccgag gcgaggtaga gaccgtcggc cgtctccaga tagtgcagcg
     9721 gcttgatgcc gaagtagtcg cgcgcaccga acgcacgccg ttcctgtcgg tcccagatca
     9781 cgaaggcgaa catgccacgc agccggctga gcacctgctc accccagtag tggtagccgg
     9841 cgacgatcac ctccccgtca ccggaggtgg cgaactgcgc cccgtagtcg cgggccaact
     9901 cctcccgcag ctcgatgtag ttgtagatct cgccgttgaa ggtcagcagg tagcgtccgc
     9961 ccgcgtaggg caacggctcg tgactggacg ccacatcgat gatcgccaac cgcttgtggg
    10021 cgaacacgcc gtccgcatac tgtccggagg cgtcgccgac aacctcaacc ccggtctcgt
    10081 ccgggccacg atgatgcagg cattccaacg cgccggcgat gtgatcgcgg tgagccgcgg
    10141 catccccgcg cgcgctgaag aaggccagga gtccgcacat ggtcgtcatc tttccacgcg
    10201 cctgtcacga ccgtagcggc cgtctgccga acgggcccgg ccgccgaccc aaccgcgtcg
    10261 gataccgtcg ggaccagtag caacgtgaag ggagtggtga tgaccgagga acgcgtcaac
    10321 cgcagtccgg agggcacgga gtcacatgat ccggcctttc cgcaggcgct cctcgcgttc
    10381 atgcggcagg gctggcggga cactgcgctg ccggtcagcc cgcgtccgga ggtgccgaac
    10441 tacgccaagc gtcgggcggc gctctccgcg gccttcccag gcgagaccct ggtgatcccc
    10501 accggcggcg agaagacacg cgccaacgac accgcgttcc ggttccgtcc gggcaccgac
    10561 ttcgcgtacc tgaccggcga ccacgcccca gacagcgtgc tcgtgctaca cccgaccgcc
    10621 tccgggcacg agcccgtcct ctacctgcgt ccccactcgt cccgacagac cgacgagttc
    10681 ttccgcagtc gccacggcga gctgtggctc ggccggcggc acaccctggc ggagaaggcg
    10741 accgagttgg gcctggccac cgccgacctc gacgaactgg acgcagcgtt ggccggcctc
    10801 gccccggccc ggacgcgggt gctgcgcggc ttcgatgccc aggtcgacgc cgcgatccgt
    10861 tcgtacgacg agcagcggga gcgggggcag ccggcccgcg accgggagtt ggccatcgcg
    10921 atctcggagc tgaggctggt caaggacgag tgggagatcg cccagcttca ggacgcagtg
    10981 gatgccaccg tccggggttt cgaggacgtg gcccgggcgc tgccggccga ccggggggtc
    11041 tccgagcggc tactcgaggg catcttcgcg ctacgggccc ggcacgacgg caacgacgtc
    11101 ggctacggct cgatcctcgg tgccggcgag cacgccacga ttctgcactg ggtgcacaac
    11161 cacggctcca cccgcccggg tgagctgctg ctgatggaca tgggagtgga gaaccaccac
    11221 ctctacacgg ccgatgtgac ccgggtgctc ccggtgagcg gccgattcac cgcgctacag
    11281 cgccaggtct acgacatcgt gtacgcctcg cagcaagccg gcatcgagtt catccggccc
    11341 ggcgtggcgt tcaaggatgt gcacctgacc tgtatgcgag tgctcgctga gggcctggcc
    11401 gacctgggtc tgctaccggt cagcgtcgac gaggcgatgg acgagaagtc ggcggtgtac
    11461 cggcggtgga cgctgcacgg tttcgggcac atgctcggca tcgacgtgca cgactgtacg
    11521 aacgctcgcg cggagatgta ccgcgacgga acgctcggcg agggctacgt gctcaccgtg
    11581 gagccgggcc tgtacttcca gcccgaggac gagttggttc cggaggaact gcgcggcatc
    11641 ggcgtccgga tcgaggacga tgtcctggtc acagcgaccg gcacggtgaa cctctccgcc
    11701 gggctgcccc gtacggccgg tgacgtggag acctggctgg ccgagcaacg ggaggctggc
    11761 ccgcgcctgc cgggctgacg tcgaccgagc caggccccgc cgcggcgcct gcgaccgtat
    11821 gagtcgctgg cgccgcggcg gggcctttcg tgtaggtagc cacgtttcga gcgccccgct
    11881 ccggctgcac cacccgcccc gaggtgagcc gaatgcgggg ttttttcaga tacatcctct
    11941 ccgcgaaaca tcttctcata cggtggtcat cggaggctgc aaccgatttg tagcaggtcg
    12001 caccaccctc atccggtgcg gaccgtctgg tagctgaaag ggcggaatgc tctgatgtcc
    12061 attgacgtaa caactcctga cggcggggcc aatgccggcc ccccgaagcg agggcggcgg
    12121 gcactctggg tcgccgccgg cgtcgtcggc ctgaccggcg tcgtcggcct ggccgccctc
    12181 ggcggtgccg tcacccgaga cgacaagacg gccggaagcg ccggccagac ggaggctacg
    12241 gaggctcagg ccaacgcccg acagaacgtc ggcgacgccg gccccaccaa ggccggcacg
    12301 accaacgaca gccagggcga ggggacgtgg agcggtggcg accagagcgg ccgagacgac
    12361 caccggagtc ccgcgcggcg cacgaagaac atcccctgca acagcgacaa gctgatccag
    12421 gccatcgtcc acgccaacca gaaccgtggc ggcgagctga cgctggccaa gggctgcacc
    12481 tacgagctga cccgaagcgt gcacggtaac ggcctgccgg tgatcaagga gccgatcgtc
    12541 ctcaagggct acgacaccac gatcgtccgc gcggccaacg ccgaacactt ccggatcttc
    12601 aacgtcgggc gcgatggcca cctgaccctc cagggcgtga ccgtcaaagg cggtcagacc
    12661 acgccccgct gggaccatta tccgacactc gaggcggcgc caccgctcac cctctcggca
    12721 caggacggag ttacccgggc aaccaaaccg accgtagccg ggtcaacggc cgcgggagcg
    12781 gtcggccgac acggcgacgg cgcggggatc ctggtccaac gcggtggcga ggccaacatc
    12841 caggacagct cggtggtact gaaccacggc cggaacggcg gtggcatcgc caactacggc
    12901 accaccacca tccggaagtc ctcggtcgag cacaacagcg ccactgggtt cggcggcggc
    12961 gtcttcaacg tcggcgtcct gcggatcgag tgggcgaaga tcgagcagaa caacgctcgc
    13021 ctgggtggtg gcggattcgc caacggctcg ttgggcttcg gcgacaaggg cggcaccgtc
    13081 tgggtgtgga gaagcacgat cagccacaac cagaccctcg gcctggccgg cggcattctt
    13141 gaccgttcgg gcgacacgag tgtcactcgt agcgaggtta cggagaacac cgcgggtcgg
    13201 gacgccggtg gagtgctcgg cgtcgacgga tcccggttgt acctggaaga ggtaatgatc
    13261 gagcggaacg tcgccacggg cgttgcaggc ggcctcgcag tggccgacga cgccaccgcg
    13321 atccttgaga agagcgtgct cgaggagaac gtggccgagg gcgtgggcgg cgccggcctg
    13381 ttcaacgcgc aggcatacgt gaccctgcgg gacagcaaga tcgtcggcaa ccgggcgatc
    13441 ggtccgttcg cggtgggcgg tggcatcgtc aacgccttcg gccaggtctc cctgatccgg
    13501 agcacggtga ccggcaactt cgccaccaca ccgccgggcg gcatcttcac caccaacgac
    13561 ggcgtcgaga tcgacgagaa gtccgcggtc aagaagaacc ggccgacgaa ctgcacgggc
    13621 agcccggtca tcccggaacg ctgcttcggt tgagacaccc ctgatgagtg caccaccaca
    13681 tagagcgggc tcctccggcc gacgtgcggc cggaggagcc ccgtatcacc ccggacgtcc
    13741 tgatgcacac cagcaacgtg atatgcgcct actacatccc ttagtacgcc tacctagcag
    13801 ttacggctga actacaccaa taacagttct cgtccgaaac catcctgcgg cgacccgtat
    13861 gtgggtttat ttcaggtaaa cgcacaaggt gaggaaaatt ctcatacggt gttgatggga
    13921 gctacaaccg atttgtagta gggacgctcg ctgtggggcg acgcgcccct gtctggtacg
    13981 aggagagggc agagagctcc aatgtccaac taccaagctc agaacaacgc catcgacccg
    14041 gaggccgcgt cgaaacgacg acgcaagctc tggctcgcca gcggcgtcgc cggcctcacc
    14101 ggggtggtca gcatcgccgc agttggcttc accggggccg gagccggtgc ccgggacctg
    14161 gcctggaaca cagcccagat caccaagaac ggcgagcagg tcgccgacga ccctggcgcg
    14221 ggccgcgtgg gcggctggga agccaaccac aggggcgact cggacggcaa tcgagacgac
    14281 agaaaccgcg ggaagaagaa gcgcgggaag gaggtgccct gcaataccga ccagctgatc
    14341 caagcgatcg tctacgccaa cagcaaccag ggcggcgtac tcaagctggc caaggactgc
    14401 acctacacgc tgacccgttc cgacaaacac ggcaacggcc tgccgatcat caaggaaccg
    14461 atcacgcttg ccggttacaa caccaagatc gtccgggaca gtcaggccga cttcttccga
    14521 attctcaacg tcggccgggg cgggcacctg aaggtcgagg gcctgaccat caagggtggg
    14581 aagaccctgg agggcgagcg gggcgcgaac acgccggagg cggtgtggtc gcgcttctcg
    14641 aactcggtcg cggcgggcga ggcggccaag gccggcaagc cgttcctgcc gctgttgcag
    14701 gccgagccgg gtgccgcagc tcggggcacc gacgcggcac gcgccgcaga aggggcacca
    14761 gccgggcgtg tggcagcagc caccgacgcg gcaccggccc ccgtctggaa cgaccgggca
    14821 ccagccggcc gatcggccac cgaaggcgca ccggctatcg acgcggcacc ggctgccgga
    14881 tggaccgacc gggcaccagc cgccgacaag gcaccagccg cggaaggcgc accggccgac
    14941 cgcctggcac cagccaccga cgcggcaccg gcccccgtct ggaccgaccg ggcaccagcc
    15001 gccgacaagg caccagccgg cggatggggc gacaaggcac cagccgcgga aggcgcaccg
    15061 gccgaccgac gggcaccagc cgccgacaag gcaccagcca ccgacgcggc accggccccc
    15121 gtctggaccg accgggcacc agccgccgac aaggcaccag ccggcggatg gggcgacaag
    15181 gcaccagccg cggaaggcgc accggccgac cgacgggcac cagccgccga caaggcacca
    15241 gccaccgacg cggcaccggc ccccgtctgg accgaccggg caccagccgc cgacaaggca
    15301 ccagccggcg gatggggcga caaggcacca gccgcggaag gcgcaccggc cgaccgacgg
    15361 gcaccagccg cagaacaggc accagccacc gacgcggcac cggcccccgt ctggaccgac
    15421 cgggcaccag ccgccgacaa ggcaccagcc ggcggatggg gcgacaaggc accagccgcg
    15481 gaaggcgcac cggccgaccg acgggcacca gccgcagaac aggcaccagc caccgacgcg
    15541 gcaccggccc ccgtctggac cgaccgggca ccagccgccg acaaggcacc agccggcgga
    15601 tggggcgaca aggcacctgc cgcgaagaag gagaagccca aggtcctccg gcacgacagg
    15661 tcaagcgacg gcgccggtgt cctcgtgcag gccggcggca ccgccgagtt cgagaagtcc
    15721 tacctggagc acaacctcgc cggcggtgtc ggaggcgggc tcgccaactt cggcaagacc
    15781 agcctctacc acaccaccgt ggccaacaat gacgccttcc actacggcgg cggcatcttc
    15841 aacgccggcg tgctgcgggt ctcctcgtcc agggtgatgg acaacggcgc cgctatcggc
    15901 ggtggcggca tcgccaacgg ggcggcgttc gtcgaccgca aggacatcga gcccggttat
    15961 gtcacggtcg aaaaggccga ggttaccggt aacgaggttc tcggcttcgg cggtggcctg
    16021 ttcgacatcg gtggcgaaac gaccgtcaag cagtcgatag tcgccaggaa cctggcgctc
    16081 ctcgccggtg gcgggatcgc ggcggtcgaa gggagcaacc tctacctgaa ggaaatggag
    16141 gttgccgaca acaccaccat cggtgacggt ggaggtctgg ctctggcact cggtgcgatc
    16201 gccaacgtgg acaagagcaa ggtccgggac aacaaagccg gcgtcttcgg gggtggcgtg
    16261 ttcaacctcc tcagcgcggt cacgttccgc aacagctcgg tctccggcaa cctcgctggt
    16321 atctccggcg gcgggatctt caacgtcgcg ggcagtgtcg acctgaccgc caccaaggtg
    16381 acgaagaacc gctccaccct cgaaccgggt ggtgtgttca gcgcactggg caaggtgacg
    16441 gtggacaaca agtccgcggt caaggggaac gacccgacca actgcaaggg cagcgttgac
    16501 cggatcgaga actgcttcgg ctgatcgacg ggtagccagt ccggccccct ccgcgtggcg
    16561 gagggggccg gaccacctgg tgcgccagta ccgatgacca caggtccagg gccaactgcg
    16621 agcaccagcg ccgagccgcc agcaaacgcc tgcgtcagcg gcgccctcaa tcccaagatc
    16681 accagatcgg gacaactcag gcctggctca gccccgagcg tcgcccacaa gcgacaggtc
    16741 gtcgaagatc tcgtagcgag ttgggtcggc cggcaggaac cagtggaagc cctcctggac
    16801 gaacactgcc accaggttcg ccgccacgat caccaggaac agcccgatga ccacctttga
    16861 cggccagccg aatcgcacgc cacgcggtac cagctcgcgg ccgaacacga ggctcacccc
    16921 gcagaacacc agcacgacgc agaacgtgat aaacgcccag gtgtacgggt gcaacccaag
    16981 aacgggcgat ccgtaaccag gatccggcgg tacgatgtgc agcaggatct ggcgggccgc
    17041 ataggcggcg ccggcgacgg cggcaacgat gctcagcccg taacccatgg cgtagtcggc
    17101 gagcgtcacg tcaccacgac gggcccgccc gatgatgtag agcggcccgc acaccaccag
    17161 catcatggcc atccgctgca ggatgcacag cgggcacgga agctctccgg tcacgaactg
    17221 caccccgaac gccgccagca gcacaccgca gtagctgagc acgaacaggt gcgcgagcca
    17281 aaaacccaga cgattggtca tgaacgcctc gatcgatcag aagttcagcg gaagtttcgt
    17341 agccgaatgg tggatgaaca gcagcagggt ggcgcacaag gcaaccgtcc acacggcaag
    17401 gaccgtcctg cgccggctgc cccgtgcggt gagccagacg ctgaggagta tcaccgcgaa
    17461 gatcaatgtg tccattactc gatagtgcag cccattacgg gatttgactc tggaatgacg
    17521 caaaccaaaa cagcagtcgg tttgatcagt cacgctgcgg gcccgatgcc tgcaccgaca
    17581 cccggcacga catccgagcc gccgacctca ccccggtcca cgagccgagg ttgcatgaat
    17641 agcaagacgg acgtacggtt tttggcatgc agtcagtgcg ggtaagggcc acctaagcac
    17701 ggcaccgcca gcaccggtgc gacagactgc aaaggactgc tcacggccac tggtgtgaag
    17761 gagtacgacg tggcgagcct cgacaccttc ggtgcgaaga cccagctgcg cgtcggagac
    17821 gcaagctacg agattttcaa gatcaacaag gtgaaggggc acgaacggct cccctacagc
    17881 ctgaagatcc tcctggagaa cctgctccgg accgaggacg gcgcgaacat caccgccgac
    17941 cacatccggc agctcggcgc ctgggaacca accgccgacc cgagcgtgga gatccagttc
    18001 accccggcgc gggtgctgat gcaggacttc accggcgtac cctgcgtggt cgacctggcc
    18061 accatgcgcg aagccgtgcg cgacctgggc ggcgacccca ccaaggtcaa cccactcgcc
    18121 ccggccgaac tggtcatcga ccactccgtc atcgccgacc tgttcggccg cgaggacgcc
    18181 ttccaacgca acgtcgaact ggagtacgag cgcaacaagg agcgctacca gttcctgcgc
    18241 tggggccaga ccgcgttcaa cgagttcaag gtcgtcccac cgggcaccgg catcgtgcac
    18301 caggtgaaca tcgagtacct ggcccgtacc gtgatggagc gcaacggcca ggcataccca
    18361 gacacggtgg tcggcaccga ctcacacacc acgatggtca acggcctcgg cgtggtcggc
    18421 tggggcgtcg gcggcatcga ggccgaggcc gccatgctcg gtcagccggt cagcatgctc
    18481 atcccgcggg tcgtgggctt caaactgtcc ggcgagatgc ccgccggcac caccgccacc
    18541 gacctggtcc tgaccatcac cgagatgctg cggcggcacg gggtggtcgg caagttcgtc
    18601 gagttctatg gcccgggtgt cagcgcggtg ccgctcgcca accgggccac catcggcaac
    18661 atgtccccgg agtacggctc caccgtcgcg atcttcccga tcgacgccga gaccgtccgc
    18721 tacctggaac tgaccggacg cgatccgcag caggtcgccc tcgtcgaggc gtacgccaag
    18781 gaacagggcc tctggcacga cccgagcgcc gaaccggact actcagagcg tctggaactg
    18841 gacctgggca gcatcgaacc gtcgctggcc ggcccgaagc gcccccagga ccgggtgccg
    18901 ctgggcaacg ccaaaacctt gttccgggcc gcactcaccg actacgtcgc caccgacgag
    18961 accggcggtg acctcggacg tgggcaggag cacggtgtca ccgggcacgc cgacgaggcc
    19021 agcgccgagt cgttcccggc cagcgacgcc cccgccaacg agatcaccga ccctgccgac
    19081 gccccacgtg acctggtgac cgcggcggtc ggtgccggcg gccgggccac cagcccgatc
    19141 cgggtcaccg gcgccgacgg caccgaattc gagctggacc atggagcggt cgtgatcgcc
    19201 gccatcacct cctgcacgaa cacctccaac ccgcaggtga tgatcggtgc ggcgctgctg
    19261 gctcgcaacg cggtggaacg gggcctggcc cgcaagccgt gggtgaagac caccctcgcc
    19321 ccgggctcga aggtcgtcat ggactactac gagcgggccg gcctgacccc gtacctggag
    19381 aagctcggct tccacctggt cggctacggc tgcaccacct gcatcggcaa ctccggccca
    19441 ttgccggagg agatctccgc ggcggtgaac gagaaggatc tcgcggtcgt ctcggtgctc
    19501 tccggcaacc gcaacttcga gggtcggatc aaccctgacg tcaagatgaa ctacctggcg
    19561 tcgccgccgc tggtggtcgc gtacgcgctc gccggcacga tggacatcga cctggccaac
    19621 gagccgatcg gcgaggacgc ccagggaacc ccggtgttcc tgcgcgacat ctggccgagc
    19681 agcaccgaaa tccaggacgt catcgcttcc gcgatcggcg ccggcggctt cagctcggcg
    19741 tacgcggacg tgttcgccgg cgacgagcgg tggcggtcgc taccgacgcc gaccggcgac
    19801 accttcgcct gggagggcga gtcgacctac gtccgcaagc ccccgtactt cgagggcatg
    19861 cgacgcgagc cggcaccggt ctccgacatc gcagccgctc gggtactggc caagctcggt
    19921 gactcggtga ccaccgacca catctcgccg gccggcgcga tcaagcccga ctcccctgcc
    19981 ggtcggtacc tcgccgagca cgatgtgccg cggcacgagt tcaactcgta cggttctcgc
    20041 cggggcaacc acgaggtgat gatccggggc accttcgcca atatccggct ccgaaaccag
    20101 ctgcgggtac ccagcgccgg ttccgccgcg ggggtcgcgc ttccggaggg tgggttcacg
    20161 gtcaaccacc tgaccggcga gcagtccacc atctacgacg ccgcggtggc ctaccaggag
    20221 acggggatcc cgctgatcgt cctggccggc aaggagtacg gctcgggctc gtcccgggac
    20281 tgggctgcca agggcacgat gttgctgggc gtcaaggcgg tcatcgccga gtcgtacgag
    20341 cggatccacc gttccaacct gatcggcatg ggcgtcctgc cgctgcagtt cccggtgggc
    20401 gagaccgctg agtcgctggg cctgaccggc accgagtcct tctccgtcac cggggtcacc
    20461 gccctcaacg gcggcgacac cccacggacg gtgcgggtca ccaccgacac cgggatcgag
    20521 ttcgacgcgg tggtccgcat cgacaccccg ggggaggcgg actacttccg gcacggtggc
    20581 attctgcagt acgtgctacg ccgaatgatc ggctgacgga gtgcaacgcc gactactcgg
    20641 ctgagcggta tcggcagggc cccacatcgg tggggccctg tcgcgtcacc gaggctggat
    20701 cccaccgcgt acccgcgggt accgctcggc cgatcggcac gccgtcgggg cagcatgccg
    20761 atcctgggcg cgacatcgcc acgctgtgcc aggctcgtgt tcatggacga caagaccatc
    20821 ctgaagcgga tctccgaact ggtcgacgag gaacaccggc tccgcaccga ggcccaggcc
    20881 aacgaggagg gcaccgacga ggagagccgc aaccggctgc gggatctggc ggagtcactg
    20941 gaccagtgct gggacctgct acgccgtcgc cgtgccgccc gcaccaccca cggcgatccg
    21001 gacgcacagg gcgtacgccc agcccccgag gtggcgcgct acctccagta gggcaggcac
    21061 cgaaccctcc cggtccgccg ccgtggtggt gccgggctgc cgcgccgact gcccagcacc
    21121 acctcggtca gcggaaggcc gccccgctga gcggtctccg gcgcgggcca cccaacgcga
    21181 gcagagttca gcgcaggccc gcctcccgga ggagctgttc ggtgagggcg agcgggtcgg
    21241 ccagcgccgc cggcaggcca cgggcggcga accaggtggc gaccacccgc acgtcccggg
    21301 ccaggaactc cggtccctgc gggttggcga ccaggtccac gacctgaggc aggtcgatga
    21361 gcaccaggcg cccttcgtgt accagcaggt tgtagggcga caggtctccg tgtgcatggc
    21421 cggctcgggc gagtaccatc agcgcctcga cgagttgtcc ccacaggtca cgcaggtccg
    21481 cctcccccgg tcgcagctgc gccaaccgtg gggccgccag accctcgtcg gggtctccga
    21541 ggaactccag catcagctcg gtgccgcgga gttggaccgg gtagggcacg gtgatcgtgc
    21601 cgtaccgcgc accgatctcc cacaggcggc cgagcacggc gaactcggcc gctgcccact
    21661 gtccggcgat catctgccga ccgaacgcgg ttcgccgggt catcgcccgc atctcccggg
    21721 atcggcggac ccgccgcccc tccagatatc ccgcgtcccg gtggaacagc cggtggtcgg
    21781 cgtcgcggta tcgcttggcc gcgagcaggc aggaccgatc ggtgtcggga acggcgcgac
    21841 ggacgagatg gacgtccgcc tccttgccgg tcttgagcac gcccagctcg gtgtctctgg
    21901 cggccagctc cgttaccagc caggcggggt acggtcgcgg accgtggacc gcgtcgtccc
    21961 aggacgacca ggtcccggcg tccggcagcg ggtcgaggtc aacgggctgc ggttcggcct
    22021 tccgcccgcg cttggcgagg tgtggttcgt catcgtcgaa gcggcgtctg ccgcgggtac
    22081 ggcgctccgg cgccggaaag tcgtgatcgc gcactgcggt gaagtccctt ggtcgaggct
    22141 gctggagtca ggtggaagtg acctgtgaag acggccatga ccgaccccct ctcctcgacc
    22201 gggccacacg cccggatgca ctgtgcggtc ccatgctcac cgccgaatca cggcgaggca
    22261 accggtatta tgccgcgagc acggcggcga cggcggcgat cgggccgtcg gcggtgtagg
    22321 tcggggcgaa ccgactgtca ttccaggtac gtccccggtg cagccagacg ctgggcagac
    22381 ccgctgccgc ggcaccgccg atgtccgcct ccgggccgtc gccgaccacc caggcgcccc
    22441 gcagcggcat gcggacgcgc tgcgcggcca acgcgaagat ccgcgggttc ggcttactga
    22501 cgccgacttc ctcggaaatg acccagtcgg cgatgtaccg gtccaacccg gtccgccgga
    22561 tcttgccctc ctgctgccgc accgctccgt tgcacaccac caccggcatc caaccgacct
    22621 cgccggcgat ccgtagcgcg caggccacca gtggatccag tcgggtgtcg gcaagcgtgc
    22681 cgtcgtgcag ttcctccacc agatcgaccg accggacgct caatgcatag cggttacgga
    22741 tcgcgtcggc cacatcccac cggtcggtca gcccgtcccc gtcgaccgcg agcagccagt
    22801 cgaggtcgcc tggtggcgcg ccgaccttga ccaggaagcg ctcagcccag gatcggaaga
    22861 ggttttcccg atcgagcagg gtgttgtcca ggtcgagaag gagcagcggc actccggcac
    22921 cttacgggac tcaggtgttc gcccgacagg ccctagcagc cttttggtca attttttgtg
    22981 acaaacaggg taagtgctgg taggacgaac gtcgagggcg catgaggaca cgcggacggc
    23041 cgggtcagcc gtattcgaag tccaagccgt acgtacggtt tgcatgacac ggagcggcct
    23101 gacacgatcg acccgtgccc agagtaagcc aggaccaact cgacgcgcgc cggcaggaga
    23161 tcctcaccgc cgcccgggtc tgcttcgccc ggcacggata cgagggcgcc accgtgcgcc
    23221 gtctcgagga agccaccggg ctgtcccgtg gcgcgatctt ccaccacttc cgcgacaagg
    23281 actcactctt cctcgccgtg gccgaggacg acgcggcggc gatggtcgag accgtcgccc
    23341 gcaacggctt ggtgcaggtg atgcgggacc tgctggcacg ggccgtctcc cccgacacga
    23401 ccggctggtt gggcagccag ctggaggtct cgcgccggct ccgcaccgac cccgcgttcg
    23461 cccggcggtg ggccgaacgg tccgcagcca tcgccgaagc cacccgcgat cgcctgcgtc
    23521 gccagcggga ggcgggagtg ctccgcgacg acgtctccat cgacgtgctg gcccagttcc
    23581 ttgagctggc atacgacggc ctggtcctgc acctggcgat gggccgaccg gccggcgacc
    23641 tcggaccggt actcaacctg gtcgaagagg ccgtccgccg tcgttga
//
