BGC0001018: micropeptin K139 biosynthetic gene cluster from Microcystis aeruginosa K-139
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Location: 1 - 33,711 nt. (total: 33,711 nt).
This entry is originally from NCBI GenBank AB481215.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001018
Short description micropeptin K139 biosynthetic gene cluster from Microcystis aeruginosa K-139
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: AB481215.1
Compounds
  • micropeptin K139
Species Microcystis aeruginosa K-139 [taxonomy]
References
Chemical products information
micropeptin K139
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C47H74N10O13
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAH22761.1
  • mcnF
 162 - 2231 (-) putative ABC transporter
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  • BAH22762.1
  • mcnA
 2804 - 6142 (+) nonribosomal peptide synthetase
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  • BAH22763.1
  • mcnB
 6145 - 9462 (+) nonribosomal peptide synthetase
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  • BAH22764.1
  • mcnC
 9459 - 23657 (+) nonribosomal peptide synthetase
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  • BAH22765.1
  • mcnE
 23920 - 28080 (+) nonribosomal peptide synthetase
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  • BAH22766.1
 28304 - 28837 (+) hypothetical protein
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  • BAH22767.1
 29850 - 30638 (+) putative methyltransferase
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  • BAH22768.1
 30796 - 31530 (+) putative acyl-carrier protein reductase
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
mcnA
Module ?
Specificity: aspartic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
mcnB
Module ?
Specificity: threonine
Evidence for specificity:
  • ATP-PPi exchange assay
  • Structure-based inference
  • Sequence-based prediction
mcnC
Module ?
Specificity: arginine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: 3-amino-6-hydroxy-2-piperidone
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: tyrosine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
mcnE
Module ?
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: CUSGWVK3I4TVHJH7NHPFAP2L, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Removed erroneous polyketide class
  • Added NRP substrate specificities
Detailed domain annotation
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Similar known gene clusters
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