BGC0001022: myxalamid biosynthetic gene cluster from Stigmatella aurantiaca
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Location: 1 - 49,736 nt. (total: 49,736 nt).
This entry is originally from NCBI GenBank AF319998.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001022
Short description myxalamid biosynthetic gene cluster from Stigmatella aurantiaca
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
AF319998.1
via
Compounds
  • myxalamid
  • myxalamid A
  • myxalamid C
  • myxalamid D
Species Stigmatella aurantiaca [taxonomy]
References
Chemical products information
myxalamid Evidence:
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C25H39N1O3
Chemical database entries
PubCHEM
myxalamid A Evidence:
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C26H41N1O3
myxalamid C Evidence:
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C24H37N1O3
myxalamid D Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAK57182.1
 2 - 1306 (-) putative aspartokinase
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    • AAK57183.1
    		 1363 - 2895 (+) putative histidine ammonium lyase
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      • AAK57184.1
      • mxaA
      		 3275 - 7822 (-) MxaA
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        • AAK57185.1
        • mxaB1
        		 7819 - 11520 (-) MxaB1
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          • AAK57186.1
          • mxaB2
          		 11487 - 14303 (-) MxaB2
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            • AAK57187.1
            • mxaC
            		 14300 - 29878 (-) MxaC
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              • AAK57188.1
              • mxaD
              		 29889 - 35411 (-) MxaD
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                • AAK57189.1
                • mxaE
                		 35479 - 41067 (-) MxaE
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                  • AAK57190.1
                  • mxaF
                  		 41064 - 48170 (-) MxaF
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                    • AAK57191.1
                    		 48435 - 49295 (+) putative acetyl transferase
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                      • AAK57192.1
                      		 49377 - 49736 (-) putative transcriptional repressor
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                        Biosynthesis information

                        Biosynthetic modules

                        Name
                        Unk01
                        Type
                        nrps-type1
                        Genes
                        mxaA
                        Substrates
                        alanine (evidence: )
                        Integrated Monomers
                        Domains
                        adenylation
                        Annotation changelog

                        Entry version: 4

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-10-07
                        Update chemical activity to schema version 2.11
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 3

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-09-15
                        Add new compound: myxalamid A
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2022-09-15
                        Add new compound: myxalamid C
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2022-09-15
                        Add new compound: myxalamid D
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2022-09-15
                        Updated bioactivity data
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2022-09-15
                        Added NRP substrate specificities
                        • (ID: 5UL74VURKJ25VSPPPO3H2NYB)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 2

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2019-10-16
                        Migrated from v1.4
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 1

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2015-06-12
                        Submitted
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        Detailed domain annotation
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