LOCUS       BGC0001026             19818 bp    DNA     linear   PLN 24-JUL-2016
DEFINITION  Metarhizium anisopliae strain ARSEF 2575 NG-391 biosynthetic gene
            cluster, partial sequence.
ACCESSION   BGC0001026
VERSION     BGC0001026
KEYWORDS    .
SOURCE      Metarhizium anisopliae
  ORGANISM  Metarhizium anisopliae
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Clavicipitaceae;
            Metarhizium.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:41:27
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 19818
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     mRNA            <1..>694
                     /product="eukaryotic aspartyl protease"
     source          1..19818
                     /db_xref="taxon:5530"
                     /mol_type="genomic DNA"
                     /organism="Metarhizium anisopliae"
                     /strain="ARSEF 2575"
     misc_feature    <1..>19818
                     /note="NG-391 biosynthetic gene cluster; putative"
     protocluster    1..19818
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[4156:16022]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4157..16022
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..19818
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[4156:16022]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      4157..16022
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..19818
                     /SMILES="C([*])C(-O)(C)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="chemical_hybrid"
                     /product="T1PKS"
                     /product="NRPS"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..19818
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001026"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..19818
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             <1..694
                     /codon_start=2
                     /note="ORF1"
                     /product="eukaryotic aspartyl protease"
                     /protein_id="ACS68551.1"
                     /transl_table=11
                     /translation="MRALAGQAKFVLGGTDQAMYDASRMQVYSIQNPSWLSEAFYPYNP
                     PKSNYWSTALTGVWISGEEESTNFIYNFSGSNNVSMQTLALLDEGSEGLGAPLSLNAYK
                     WLVKQVNGTRASNATVQAIMAQGSSGYNGASQDWYTVPCNSTGSRPTLVYELDGRQNYT
                     IPESDYIIRLESAATPVCYLNVNVWKYGRTSSGDSKVLLLGGAFLKRLYVQLDFENLSF
                     GLAPLKKH"
     mRNA            complement(join(<1264..1875,1949..>2002))
                     /product="eEF-1B gamma subunit-like protein"
     CDS             complement(join(1264..1875,1949..2002))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_N_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1193:glutathione S-transferase (Score: 138.1; E-value:
                     4.8e-42)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF2"
                     /product="eEF-1B gamma subunit-like protein"
                     /protein_id="ACS68552.1"
                     /sec_met_domain="GST_N_3 (E-value: 7e-10, bitscore: 28.1,
                     seeds: 52, tool: rule-based-clusters)"
                     /sec_met_domain="GST_C (E-value: 6.5e-17, bitscore: 50.4,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPFGKIYSFMPNGRVFKIMAAAKLNNLDIEVADYQHMVTNKSAG
                     FLEKFPLGKVPAFEGVDGLCLFESDAIARYIAASGPFSSQLLGSDAATSAQIQQWVSFT
                     EGEIYQAVLELVMWRVGMRPFEESTECKALDKLERGLSILEGHLKNREWLVGPQLTLAD
                     LTAASALVWAFMHIIDEPMREEFPKTTAWYLRVIGTTGIESVFGPPNLITARRTGPTC"
     mRNA            complement(<2466..>3746)
                     /product="alpha/beta hydrolase"
     CDS             complement(2466..3746)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF3"
                     /product="alpha/beta hydrolase"
                     /protein_id="ACS68553.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.8e-12, bitscore:
                     35.1, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 7.9e-09, bitscore:
                     23.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQVFPSTFFNFEFLRLLGTVPYYGAEVGECLETASRIKDGDPET
                     WYQAWWDIGQEVLSQAEDAAKTGDKTAASWAYIRSANYFRASEFLLHCTPNDPRILAAS
                     RASVDAFNKGWVLLDADVREVEIPYDNDKTLPGRLYLPAAQHRVTQKLPLIVQTGGFDS
                     TQEELYFYGAAGALPRGYAVLTFDGPGQGRALREKKLYLRPDWEHVTGQVLDFVVDKLS
                     SEYDLDLDRLSVFGASLGGYLSLRAATDARIKACITVDGPFDLFEITKSRMPAWFINGW
                     LSGWLSDKFVNSVIGCLERVNFQLAWEFGHSKWVYGVDTPADVLRFMQKFTLHSTKNAV
                     LSNIKCPTLVTGAADSFYFTPDQNAHKIMEGLTCLSDTQKRLWIGNGVKGGGLQAKIGA
                     LALVHYEMFAWLDKTFGIERENLINKV"
     mRNA            join(<4157..11539,11598..>16022)
                     /product="hybrid PKS-NRPS protein"
     CDS             join(4157..11539,11598..16022)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (10-443). E-value:
                     1.2e-168. Score: 553.2. Matches aSDomain:
                     nrpspksdomains_ACS68554.1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (548-863). E-value: 1.4e-92.
                     Score: 302.1. Matches aSDomain:
                     nrpspksdomains_ACS68554.1_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (935-1110). E-value: 1.2e-25.
                     Score: 82.7. Matches aSDomain:
                     nrpspksdomains_ACS68554.1_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1362-1562). E-value: 6.6e-91.
                     Score: 296.5. Matches aSDomain:
                     nrpspksdomains_ACS68554.1_cMT.1"
                     /NRPS_PKS="Domain: PKS_KR (2085-2261). E-value: 5.1e-51.
                     Score: 165.0. Matches aSDomain:
                     nrpspksdomains_ACS68554.1_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2371-2442). E-value: 1e-12.
                     Score: 40.1. Matches aSDomain:
                     nrpspksdomains_ACS68554.1_PKS_PP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (2522-2807). E-value:
                     8.4e-62. Score: 200.7. Matches aSDomain:
                     nrpspksdomains_ACS68554.1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (2972-3387). E-value: 5e-91.
                     Score: 297.1. Matches aSDomain:
                     nrpspksdomains_ACS68554.1_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (3505-3574). E-value:
                     9.1e-12. Score: 37.3. Matches aSDomain:
                     nrpspksdomains_ACS68554.1_PP-binding.1"
                     /NRPS_PKS="Domain: TD (3619-3849). E-value: 6.3e-66. Score:
                     213.9. Matches aSDomain: nrpspksdomains_ACS68554.1_TD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 225.7; E-value:
                     1.8e-68)"
                     /gene_kind="biosynthetic"
                     /note="NGS1; ORF4"
                     /product="hybrid PKS-NRPS protein"
                     /protein_id="ACS68554.1"
                     /sec_met_domain="itr_KS (E-value: 5.3e-178, bitscore:
                     580.7, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.5e-93, bitscore: 302.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 8.1e-49, bitscore:
                     154.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2e-51, bitscore:
                     163.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.9e-95, bitscore:
                     307.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.8e-13, bitscore:
                     37.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 8.1e-46, bitscore:
                     144.8, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQNSIVREPIAVVGVACRFPGEATSPSKLWDLVCEKRDVQKPIS
                     SDRFNSDAFYNSNGEASGCTDVKRAYLLSEDIRLFDASFFRTNALEAEAMDPQQRLLLE
                     TVYEAIESAGLPLEDLKGSDTAVYVGSMTGDYHEMLLRDPQDMPKYMATGTARSILSNR
                     LSYFFDWKGPSMTIDTACSSSLVAVHEAVTALRLGVSTIACAAGANLILGPEMMISESN
                     LHMLSPTGRSRMWDASANGYGRGEGTAAVIMKTLLQALKDGDYIHGIIRETGVNSDGRT
                     NGITLPSSESQTALIRQTYKAAGIDLALERCQFFEAHGTGTPAGDPIEARAIYEAFFDG
                     EESTSNTTGNIYVGSVKSTIGHLEGCAGLAGLIKTMEAVRRGTIPPNMGFKKLNPKIER
                     FSKNLIVPTEALPWPELPEGTPRRASVNSFGFGGTNAHAIIENFEAAQHGQSPRDIIVT
                     PVVLSANSEKSLREQAIQLNAAMQLADESRLRDIMYTLSHRRSQLPLRTFFVGHSAEEV
                     KKSVKDALAEDGTFTVHKDEKPSHQPSRILGVFTGQGAQWPTMGREILKESKFAQEVVK
                     TLEQSLASLPEPPTWTLSEQIFADAAASRLSEAEVSQPLCTAVQLMLVEMLRAAGIQFS
                     GVIGHSSGEIAAAYCAGFLSASDAIRVAYYRGVCAKLAKGSNGKSGAMMAVGLSYEEAL
                     QFCNNEFDSRLDVAASNAPASTTISGDEDAIQEAKALLDQRSIFARVLKVDTAYHSHHM
                     LPCAGPYSSLLKECGVRSLSGNPACEWYSSVICERIDGTRHDGILGAEYWRDNMVNAVK
                     FSSAAELAIQSGEDFDVVLEVGPHPALKGPFEQTVKQVSDSTPPYQATLMRNIHDIDAL
                     SKTLGFLWSRLGKSVVDFSAYAACFDVLPGRMADNMPTYPWDHGQSFWKESRKSANFRL
                     RTHPPHPLLGVRSSEDMGPEMRWLNILRVNEIPWLEGHKVQGQVIYPAAAYLVMAMEAA
                     KAIDETKLVQLVELYDVRILSAIQLAQSSQGVEISFSLNITEKDDNSSVAEWACYTSSS
                     TNTANWKCHAKGHVRVEFAMPVDGHLPPRNPPDVSLSTLDMDRFYECLTDIGLQYSLEF
                     RSLSSVQRRLGYATASVSHIATDFGATIHPALLDSSFQSLFAAYCWPGDGTLNCPFVPT
                     YLKRLRILNIGVPEGEPLVIDSYLTSVNVSDITCDIDIALTDKNKPFVQLEGLTCTSLL
                     RHDPKNSKELYTRTEWEVDVHSEIRTLEVAQSDEQQNLGLVDLCERFAYYYLRNLDRVV
                     HRKEVETMEWHYQRVFEWIDYLFPMIEMGKHPTIKPEWSEDQLPWLMEQKSQYPDQIDL
                     MLIQAVGENLPAVVRKQTTMLEHMVKDDVLNRFYKEGLGFQRANGYMSRISRQIAHRYP
                     RMNILEIGAGTGGATKGILQSLGSTFGTYTFTDVSTGFFEAAAEQFSPWADKMVFKALN
                     IENSPTEQGYSEASYDLVIASNVLHATKTLSETMRNVRRLLKPGGFLLLLEVTSDIVRV
                     KMMMSGLSGWWLGGDDGRRHGPTITVPEWDTLLRSTGFSGVDNTFNDFGHSSKYMTSVM
                     LSQAMDERVEFLRQPLSSRGDSTMADSLTIVGGTQGNVANIIARHLADCHPRLVVQCVA
                     GFEDFASPLNSTAMKSLLVLQDLDEPVLQKLASSTLGGLQKAIDQCRQVLWVSSGCRKD
                     NPFANMSVGLCRSLSSEYPHIKIQHIDVETRLDQGTMHRISEAALRLLHLEKLSADTLW
                     SFEPELILEDKKWYIPRLVPDEKLNQRLTSTKMAVQVDTSLKERTVEIVSEASKYIVTQ
                     SVPCIDAEQQTPLTTINVTKALLHPVATECHKDYFLCYGYRDSCPDIPVLALATANASS
                     VSVPEHFVFDLPAVVTDGAAALQRAAFSVVAEQVLEDVDTPGTIFLHNEDQRFSLVVRQ
                     AAAELGLRCIATTSQEPASSTSQSIFIHPHASQRVLKALIPQNAKRFIDFSTDVVDQSR
                     FRDCLPPTCRFYALNHMVATGSNVSGISVQQAIKALTSTLDSCLSSTVNQVSISELHAQ
                     AAARFPYGTVVDFVGESTIARVPPLQSTRLFRCDKTYLLAGCTGGFGKALCRWMVASGV
                     RHLALTTRNISAVDEVWVREIERAGACLKLYQVDVSDKNALQAVYEDIGRNMPPVVGVA
                     NAAMVLSDKSFGELKTDNFDIVFGPKVRGTQNLHDIFKGQALDFFIMFSSLASVVGNRG
                     QSNYAAANLFMTTIAEQRRASNLAASVIHIGMVLGVGYVSSTGTYENTLRQYNYMPISE
                     SDFLNMFSQAILIGHPRSNHPCELITGLNRYSLNSDAQQYFWHENMRFSHHYIEEEQRK
                     VSTATRTSVSERLEDARGSEEILAVIEEEFCTKLERMLQAEAGTIKASQSLANLGVDSL
                     VAVEIRSWFFKEADVDIPVLDVLNTGTISELCQRAAQSVAAAQLSDAEECAKPDDKSPI
                     LLSANIPESNESTAANTSVPHSLFEESSRGGSETPSEDMGSSDISLPSRRDFEFERCGR
                     LSFAQERLWFLQKYLQDPTTYNVSMAYKISGPLRRRDFEDAFEKVIQRHASLRTGFYVD
                     ADTSLPMQRVYKYPHFRFTHKEGADYEEEYHNMQKMRYDLESGDVISATIIRYTDQEHV
                     FILGFHHIAMDGFSAQILVKDLIDAYGGLTISSGCNEYLDYAIHQRDAGIPVEISKFWM
                     SEFNTLPPVLPLFDFAECKTRTPLLDYKTKAVERTVPTTVSSKVKILARQLGATPFHIY
                     LAALQALLYDINSNKDICIGITDANKTDPAYLDTIGFFVNLVPIRFHIDESEAVLELVA
                     RSKKTATNALSNSMPFDVLLDDLQVPRSTTHSPLFQVILNYKMGSTQTVRFEDCEAEIL
                     RFPGASNAFDLAFDIGNFPDGSASISLKTQAYMYTDLELRFILDSYIRILSSFVSNPSQ
                     KLHEVTALSEDEKEKSLQLGRGRQLPDPRLETVAHFFEDWALTQPLKIALREDSGAEFT
                     YRQIQSIVNAFTETLHGAGLGPGSKVCVYCEPGTHILAALLAISKIGGIYIPLDPQNPT
                     ERLQLIVNDCEPDAILCDDVTSTLASLLKSAGKSINVTDIDTSATTTSIPDWNKAKGDS
                     AAFVFYTSGTTGVPKGIALTHSNVVHHINSIMHFYSIKRGVVLQQAPLGFDMSLTQMTL
                     TMMTGGTLVVASSATRRDPRQIASLMYANKVTHTFMTPTLALALIRHGYDALARCSDWE
                     FSLLSGEAFRAHVVHEFRRLGLAGLKLYNGYGPTEITINSSSGMDELDEAAPRDTRNPS
                     IGATLPNYTNYILDKNMQPVRIGNAGELFVGGAGIALGYLRRDKLNKEKFLPDPFASAD
                     NRARGWCRMYRTGDKAKFLPDGRIVFLGRIQGDSQVKLRGFRIELVDISNTIIKSSHGN
                     ITEAGISLRRNGNGSDDESFLVAFAVVSHSFDHPEPSAFFKKLLNDLQLPRYMIPAKIV
                     PVDRLPMSSSGKLDQNVLDSLPVPKEEESNQSPLTDTQERLKKLWVEALPPIGATAVID
                     QDVDFFQVGGNSLRIILLRESISREFCVSVSVFDLFANSTLGRMAARIDESTDTTTSPE
                     TIDWNTETLFDVPVIETCEDDSYKQHRATSDGLEIILTGATGFLGSAILASLVQDARVS
                     KVHCVAIRQPLKSLTAEQPIFKSPRVSCYAGDLSLPRLGLSTSDFTQLSANTDKIIHNG
                     ADVSFLKSYQSLRATNVGSTKEIVRMAALHRIPIHFISTGGLANLTNLDGLPQVSVSSF
                     TPPVDGSQGYIATKWASEVYLENVVTRLGIPVWIHRPSNITGIRSPSVDLMQIIFKYSE
                     QIKAVPEIDGWKGCFDFVPVETVARGIVCAIHEPGVQQGTRPIYRHHCGRDKIPVTGIR
                     EHLETKVGARIDSVGIEEWLSRAQSVGLDDTAAALVSSTFAQSSTKTVPWLRSGD"
     aSDomain        4187..5485
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACS68554.1_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.20E-168"
                     /label="ACS68554.1_PKS_KS.1"
                     /locus_tag="ACS68554.1"
                     /protein_end="443"
                     /protein_start="10"
                     /score="553.2"
                     /tool="antismash"
                     /translation="IAVVGVACRFPGEATSPSKLWDLVCEKRDVQKPISSDRFNSDAFY
                     NSNGEASGCTDVKRAYLLSEDIRLFDASFFRTNALEAEAMDPQQRLLLETVYEAIESAG
                     LPLEDLKGSDTAVYVGSMTGDYHEMLLRDPQDMPKYMATGTARSILSNRLSYFFDWKGP
                     SMTIDTACSSSLVAVHEAVTALRLGVSTIACAAGANLILGPEMMISESNLHMLSPTGRS
                     RMWDASANGYGRGEGTAAVIMKTLLQALKDGDYIHGIIRETGVNSDGRTNGITLPSSES
                     QTALIRQTYKAAGIDLALERCQFFEAHGTGTPAGDPIEARAIYEAFFDGEESTSNTTGN
                     IYVGSVKSTIGHLEGCAGLAGLIKTMEAVRRGTIPPNMGFKKLNPKIERFSKNLIVPTE
                     ALPWPELPEGTPRRASVNSFGFGGTNAHAIIENF"
     aSModule        4187..11482
                     /complete
                     /domains="nrpspksdomains_ACS68554.1_PKS_KS.1"
                     /domains="nrpspksdomains_ACS68554.1_PKS_AT.1"
                     /domains="nrpspksdomains_ACS68554.1_PKS_DH.1"
                     /domains="nrpspksdomains_ACS68554.1_cMT.1"
                     /domains="nrpspksdomains_ACS68554.1_PKS_KR.1"
                     /domains="nrpspksdomains_ACS68554.1_PKS_PP.1"
                     /iterative
                     /locus_tags="ACS68554.1"
                     /monomer_pairings="pk -> Me-pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       4670..4717
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0001"
                     /evalue="5.10E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="ACS68554.1"
                     /protein_end="187"
                     /protein_start="171"
                     /score="21.5"
                     /tool="antismash"
                     /translation="GPSMTIDTACSSSLVA"
     CDS_motif       4859..4897
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0002"
                     /evalue="1.60E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="ACS68554.1"
                     /protein_end="247"
                     /protein_start="234"
                     /score="11.7"
                     /tool="antismash"
                     /translation="WDASANGYGRGEG"
     CDS_motif       5099..5143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0003"
                     /evalue="2.30E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="ACS68554.1"
                     /protein_end="329"
                     /protein_start="314"
                     /score="10.6"
                     /tool="antismash"
                     /translation="FEAHGTGTPAGDPIE"
     CDS_motif       5801..5851
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0004"
                     /evalue="7.70E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ACS68554.1"
                     /protein_end="565"
                     /protein_start="548"
                     /score="15.3"
                     /tool="antismash"
                     /translation="VFTGQGAQWPTMGREIL"
     aSDomain        5801..6745
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACS68554.1_PKS_AT.1"
                     /evalue="1.40E-92"
                     /label="ACS68554.1_PKS_AT.1"
                     /locus_tag="ACS68554.1"
                     /protein_end="863"
                     /protein_start="548"
                     /score="302.1"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFTGQGAQWPTMGREILKESKFAQEVVKTLEQSLASLPEPPTWTL
                     SEQIFADAAASRLSEAEVSQPLCTAVQLMLVEMLRAAGIQFSGVIGHSSGEIAAAYCAG
                     FLSASDAIRVAYYRGVCAKLAKGSNGKSGAMMAVGLSYEEALQFCNNEFDSRLDVAASN
                     APASTTISGDEDAIQEAKALLDQRSIFARVLKVDTAYHSHHMLPCAGPYSSLLKECGVR
                     SLSGNPACEWYSSVICERIDGTRHDGILGAEYWRDNMVNAVKFSSAAELAIQSGEDFDV
                     VLEVGPHPALKGPFEQTVKQVSDSTPPYQATLMR"
     CDS_motif       6047..6154
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0005"
                     /evalue="6.20E-11"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="ACS68554.1"
                     /protein_end="666"
                     /protein_start="630"
                     /score="34.7"
                     /tool="antismash"
                     /translation="GIQFSGVIGHSSGEIAAAYCAGFLSASDAIRVAYYR"
     aSDomain        6962..7486
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACS68554.1_PKS_DH.1"
                     /evalue="1.20E-25"
                     /label="ACS68554.1_PKS_DH.1"
                     /locus_tag="ACS68554.1"
                     /protein_end="1110"
                     /protein_start="935"
                     /score="82.7"
                     /tool="antismash"
                     /translation="HPLLGVRSSEDMGPEMRWLNILRVNEIPWLEGHKVQGQVIYPAAA
                     YLVMAMEAAKAIDETKLVQLVELYDVRILSAIQLAQSSQGVEISFSLNITEKDDNSSVA
                     EWACYTSSSTNTANWKCHAKGHVRVEFAMPVDGHLPPRNPPDVSLSTLDMDRFYECLTD
                     IGLQYSLEFRSL"
     CDS_motif       7046..7123
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0006"
                     /evalue="1.20E-11"
                     /label="PKSI-DH_m2"
                     /locus_tag="ACS68554.1"
                     /protein_end="989"
                     /protein_start="963"
                     /score="37.0"
                     /tool="antismash"
                     /translation="WLEGHKVQGQVIYPAAAYLVMAMEAA"
     aSDomain        8243..8842
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACS68554.1_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="6.60E-91"
                     /label="ACS68554.1_cMT.1"
                     /locus_tag="ACS68554.1"
                     /protein_end="1562"
                     /protein_start="1362"
                     /score="296.5"
                     /tool="antismash"
                     /translation="MLEHMVKDDVLNRFYKEGLGFQRANGYMSRISRQIAHRYPRMNIL
                     EIGAGTGGATKGILQSLGSTFGTYTFTDVSTGFFEAAAEQFSPWADKMVFKALNIENSP
                     TEQGYSEASYDLVIASNVLHATKTLSETMRNVRRLLKPGGFLLLLEVTSDIVRVKMMMS
                     GLSGWWLGGDDGRRHGPTITVPEWDTLLRSTGFSGVD"
     CDS_motif       8984..9049
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0007"
                     /evalue="9.90E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="ACS68554.1"
                     /protein_end="1631"
                     /protein_start="1609"
                     /score="-1.0"
                     /tool="antismash"
                     /translation="VGGTQGNVANIIARHLADCHPR"
     aSDomain        10412..10939
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACS68554.1_PKS_KR.1"
                     /evalue="5.10E-51"
                     /label="ACS68554.1_PKS_KR.1"
                     /locus_tag="ACS68554.1"
                     /protein_end="2261"
                     /protein_start="2085"
                     /score="165.0"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="KTYLLAGCTGGFGKALCRWMVASGVRHLALTTRNISAVDEVWVRE
                     IERAGACLKLYQVDVSDKNALQAVYEDIGRNMPPVVGVANAAMVLSDKSFGELKTDNFD
                     IVFGPKVRGTQNLHDIFKGQALDFFIMFSSLASVVGNRGQSNYAAANLFMTTIAEQRRA
                     SNLAASVIHIGMV"
     CDS_motif       10415..10513
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0008"
                     /evalue="1.00E-13"
                     /label="PKSI-KR_m1"
                     /locus_tag="ACS68554.1"
                     /protein_end="2119"
                     /protein_start="2086"
                     /score="43.8"
                     /tool="antismash"
                     /translation="TYLLAGCTGGFGKALCRWMVASGVRHLALTTRN"
     CDS_motif       10787..10897
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0009"
                     /evalue="1.10E-21"
                     /label="PKSI-KR_m4"
                     /locus_tag="ACS68554.1"
                     /protein_end="2247"
                     /protein_start="2210"
                     /score="69.5"
                     /tool="antismash"
                     /translation="LDFFIMFSSLASVVGNRGQSNYAAANLFMTTIAEQRR"
     aSDomain        11270..11482
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACS68554.1_PKS_PP.1"
                     /evalue="1.00E-12"
                     /label="ACS68554.1_PKS_PP.1"
                     /locus_tag="ACS68554.1"
                     /protein_end="2442"
                     /protein_start="2371"
                     /score="40.1"
                     /tool="antismash"
                     /translation="IEEEFCTKLERMLQAEAGTIKASQSLANLGVDSLVAVEIRSWFFK
                     EADVDIPVLDVLNTGTISELCQRAAQ"
     aSDomain        11781..12635
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACS68554.1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="8.40E-62"
                     /label="ACS68554.1_Condensation_LCL.1"
                     /locus_tag="ACS68554.1"
                     /protein_end="2807"
                     /protein_start="2522"
                     /score="200.7"
                     /tool="antismash"
                     /translation="RLSFAQERLWFLQKYLQDPTTYNVSMAYKISGPLRRRDFEDAFEK
                     VIQRHASLRTGFYVDADTSLPMQRVYKYPHFRFTHKEGADYEEEYHNMQKMRYDLESGD
                     VISATIIRYTDQEHVFILGFHHIAMDGFSAQILVKDLIDAYGGLTISSGCNEYLDYAIH
                     QRDAGIPVEISKFWMSEFNTLPPVLPLFDFAECKTRTPLLDYKTKAVERTVPTTVSSKV
                     KILARQLGATPFHIYLAALQALLYDINSNKDICIGITDANKTDPAYLDTIGFFVNLVPI
                     RFHI"
     aSModule        11781..15761
                     /complete
                     /domains="nrpspksdomains_ACS68554.1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ACS68554.1_AMP-binding.1"
                     /domains="nrpspksdomains_ACS68554.1_PP-binding.1"
                     /domains="nrpspksdomains_ACS68554.1_TD.1"
                     /final_module
                     /locus_tags="ACS68554.1"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       11838..11951
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0010"
                     /evalue="1.60E-13"
                     /label="C2_LCL_024-062"
                     /locus_tag="ACS68554.1"
                     /protein_end="2579"
                     /protein_start="2541"
                     /score="43.0"
                     /tool="antismash"
                     /translation="TTYNVSMAYKISGPLRRRDFEDAFEKVIQRHASLRTGF"
     CDS_motif       12150..12215
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0011"
                     /evalue="1.90E-08"
                     /label="C3_DCL_135-156"
                     /locus_tag="ACS68554.1"
                     /protein_end="2667"
                     /protein_start="2645"
                     /score="26.8"
                     /tool="antismash"
                     /translation="FHHIAMDGFSAQILVKDLIDAY"
     CDS_motif       12537..12626
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0012"
                     /evalue="1.60E-07"
                     /label="C5_LCL_267-296"
                     /locus_tag="ACS68554.1"
                     /protein_end="2804"
                     /protein_start="2774"
                     /score="23.8"
                     /tool="antismash"
                     /translation="DICIGITDANKTDPAYLDTIGFFVNLVPIR"
     CDS_motif       12675..12791
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0013"
                     /evalue="3.90E-10"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ACS68554.1"
                     /protein_end="2859"
                     /protein_start="2820"
                     /score="32.0"
                     /tool="antismash"
                     /translation="KKTATNALSNSMPFDVLLDDLQVPRSTTHSPLFQVILNY"
     aSDomain        13131..14375
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACS68554.1_AMP-binding.1"
                     /evalue="5.00E-91"
                     /label="ACS68554.1_AMP-binding.1"
                     /locus_tag="ACS68554.1"
                     /protein_end="3387"
                     /protein_start="2972"
                     /score="297.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEDWALTQPLKIALREDSGAEFTYRQIQSIVNAFTETLHGAGLGP
                     GSKVCVYCEPGTHILAALLAISKIGGIYIPLDPQNPTERLQLIVNDCEPDAILCDDVTS
                     TLASLLKSAGKSINVTDIDTSATTTSIPDWNKAKGDSAAFVFYTSGTTGVPKGIALTHS
                     NVVHHINSIMHFYSIKRGVVLQQAPLGFDMSLTQMTLTMMTGGTLVVASSATRRDPRQI
                     ASLMYANKVTHTFMTPTLALALIRHGYDALARCSDWEFSLLSGEAFRAHVVHEFRRLGL
                     AGLKLYNGYGPTEITINSSSGMDELDEAAPRDTRNPSIGATLPNYTNYILDKNMQPVRI
                     GNAGELFVGGAGIALGYLRRDKLNKEKFLPDPFASADNRARGWCRMYRTGDKAKFLPDG
                     RIVFLGRIQGDSQVKL"
     CDS_motif       13557..13616
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0014"
                     /evalue="2.80E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ACS68554.1"
                     /protein_end="3134"
                     /protein_start="3114"
                     /score="22.9"
                     /tool="antismash"
                     /translation="AFVFYTSGTTGVPKGIALTH"
     CDS_motif       14148..14234
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0015"
                     /evalue="1.40E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="ACS68554.1"
                     /protein_end="3340"
                     /protein_start="3311"
                     /score="30.2"
                     /tool="antismash"
                     /translation="IGNAGELFVGGAGIALGYLRRDKLNKEKF"
     CDS_motif       14355..14405
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0016"
                     /evalue="6.10E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="ACS68554.1"
                     /protein_end="3397"
                     /protein_start="3380"
                     /score="18.8"
                     /tool="antismash"
                     /translation="GDSQVKLRGFRIELVDI"
     aSDomain        14730..14936
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACS68554.1_PP-binding.1"
                     /evalue="9.10E-12"
                     /label="ACS68554.1_PP-binding.1"
                     /locus_tag="ACS68554.1"
                     /protein_end="3574"
                     /protein_start="3505"
                     /score="37.3"
                     /tool="antismash"
                     /translation="ERLKKLWVEALPPIGATAVIDQDVDFFQVGGNSLRIILLRESISR
                     EFCVSVSVFDLFANSTLGRMAARI"
     aSDomain        15072..15761
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACS68554.1_TD.1"
                     /evalue="6.30E-66"
                     /label="ACS68554.1_TD.1"
                     /locus_tag="ACS68554.1"
                     /protein_end="3849"
                     /protein_start="3619"
                     /score="213.9"
                     /tool="antismash"
                     /translation="IILTGATGFLGSAILASLVQDARVSKVHCVAIRQPLKSLTAEQPI
                     FKSPRVSCYAGDLSLPRLGLSTSDFTQLSANTDKIIHNGADVSFLKSYQSLRATNVGST
                     KEIVRMAALHRIPIHFISTGGLANLTNLDGLPQVSVSSFTPPVDGSQGYIATKWASEVY
                     LENVVTRLGIPVWIHRPSNITGIRSPSVDLMQIIFKYSEQIKAVPEIDGWKGCFDFVPV
                     ETVARGIV"
     CDS_motif       15075..15140
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACS68554.1_0017"
                     /evalue="2.00E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="ACS68554.1"
                     /protein_end="3642"
                     /protein_start="3620"
                     /score="1.2"
                     /tool="antismash"
                     /translation="ILTGATGFLGSAILASLVQDAR"
     mRNA            complement(<16691..>17191)
                     /product="hypothetical protein"
     CDS             complement(16691..17191)
                     /codon_start=1
                     /note="ORF5"
                     /product="hypothetical protein"
                     /protein_id="ACS68555.1"
                     /transl_table=11
                     /translation="MASGAFFDPLVALRALPLVSSTCTLLFGWDQTFFLGIMNRPENRA
                     KSKPLLQSYFNTFFYRGLPFVVGAIGVSTWSGVGNLFAQRSVLQSRQSYWWYAAGTIAA
                     ASHLLFVPLIAPSVKDMMDGKEQTDANDCLDEWLRVNNVRTWTVDLLAWGAFMVAAGKT
                     LCH"
     mRNA            <17452..>19101
                     /product="major facilitator superfamily protein"
     CDS             17452..19101
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 329.3; E-value:
                     4.8e-100)"
                     /gene_kind="transport"
                     /note="ORF6"
                     /product="major facilitator superfamily protein"
                     /protein_id="ACS68556.1"
                     /transl_table=11
                     /translation="MATDINVLAGGAAVDAGSQTNKKGLKFWLVFAAISLTTFLAALDT
                     SIISTALPTIAADLGSESLYVWIIDSYLLASTATIPIFAQAANIYGRRSLILISVLLFA
                     LGSGLCGGASNNAMMIGGRSVQGVGGGGILTMSEIIVCDLVSIRERGLYAGIIGGIWAV
                     ASVIAPIIGGAFAQNITWRWIFYINLPISGVSIIALALFLQLRRPPAGTIKSQVARIDW
                     GGSFLLITSITAIILALSWGGSTNPWSSWRTIVPLVLGFIGLVFFFVYQAAPWLTDLTM
                     PLRLFGNRTAVTVFIMSFIHSMLLFWVCYFLPVYFQGVKEASPSRSAVMLFPIATTSAP
                     GGVIAGISITKTGTYRIWHFLGFGLMALGCGLFTLFDETTPTGQWVGFQLLFGFGCGFV
                     FTSCLPPILASLPDSDVATATGAWTFLRNFGSIWGIAIPAAVFNTHANKFASEVSDPSV
                     RALLVNGGAYGHATREFITMFDGDPALKSEILSLYIRGLKVVWEVSIAFALPWAWLLLS
                     LFPSIELRDELNTEYGMKEAETKPTTDLGDKA"
ORIGIN
        1 aaatcgtgcc ttggcggggc aagccaaatt cgtgcttgga ggcacagatc aagccatgta
       61 tgacgcatcc agaatgcagg tttatagcat tcagaaccct tcatggctct cggaggcgtt
      121 ttacccgtat aatccaccga aaagcaacta ctggagtacc gcccttacgg gagtttggat
      181 ctcgggcgaa gaagagtcta ccaactttat ttacaatttc tcaggctcaa acaatgtttc
      241 catgcaaact ctggcactgt tagacgaggg ttcagaaggc ctgggtgcac cattgtcgct
      301 gaatgcgtat aagtggttgg taaaacaagt caacggcaca cgggccagta acgccacagt
      361 ccaagctatc atggcacaag ggtcttcggg ctacaacgga gcaagccaag actggtatac
      421 ggttccgtgt aacagtacag gcagccggcc gacattagtg tatgagctag atggacgaca
      481 gaattacaca atcccggaat ctgactacat catcagactc gagtccgcgg cgactcctgt
      541 gtgctacctc aatgtaaatg tttggaagta tggacgaact agttcggggg actcaaaagt
      601 cctcttgctg ggaggtgcgt ttctcaaacg actttatgtc cagctagact ttgagaatct
      661 ctcgtttggg cttgctcccc tcaagaagca ttaggtttca ggatatcaag cccgcgagtg
      721 atcaagtggc aaaagtaaga tcgtttattc agtttttccg gtttttcttt tgtatctgta
      781 atgtttcaag tagttcacaa aaaattatat cgcgaaacat taaacatttc tacaagtgga
      841 ccacgcgatg ctatttgaga ggctctgttc aatctggtgc ttataccatt gacgataaaa
      901 tgctatatat gttccggaga atcttagacg agtactgaag aaaagaaaat gagtccatgt
      961 gtagtgggag taatcaactt cgctaattta acaactgtca actgggccca gagaacaagc
     1021 cttgaactcc agctccgttt actactcggt gcatccgttc ttggtccatc actaactcta
     1081 cctacatatg tactctcttg gacgaatagg gctattgatt cctttcacag ttaggaggct
     1141 cattgaagtc tcgtttcatg actcaagttc aatgactaag tgatagaaac taaatatagc
     1201 attatccgtc taccctttgt aatccacatt cagaccttta gtcccaaacg tgtatatcgc
     1261 cgctcaacag gttggcccag tacgcctggc cgtaatcaag tttggtggtc caaacacgga
     1321 ttcaatgcca gtcgtcccga taacccgcaa ataccaggcc gtcgtcttgg ggaattcttc
     1381 gcgcattggc tcatcgatga tatgcataaa cgcccacaca agagccgacg cagccgtcaa
     1441 gtcagccaga gttagttgcg gaccaaccag ccactcccta ttcttcaaat gaccttccag
     1501 aatactcaga ccacgctcga gtttatcgag agccttgcac tccgtgcttt cttcaaacgg
     1561 gcgcatacca actctccaca tcactagctc gagtacggct tggtagatct ctccttctgt
     1621 aaagctcacc cactgttgaa tctgtgcgga tgtcgctgca tcggagccaa gtagctggga
     1681 agaaaacggt ccggaagcag caatgtatcg cgcgatagcg tctgattcaa aaaggcatag
     1741 accgtccacg ccctcgaagg cagggacttt acccaaaggg aatttctcca gaaacccggc
     1801 ggatttgttc gttaccatgt gctggtagtc tgcgacctca atgtcaagat tgttcaactt
     1861 ggcagctgcc atgatctaga gcccgtggtt aattcatggc tatgtcaaat ttggttgtca
     1921 ttgctttgat gtgactcaaa gaactgacct tgaaaactcg gccatttggc atgaacgagt
     1981 agatttttcc aaatggcgcc attatgacaa agtgctaatt tgtccaaaac aaactgttca
     2041 ttggccaaga caagtgtaag ttccgtgtgc cggggatgca tatatgcttg ccaagatggt
     2101 ctggttcggc gacttacata cgggcctggg ccgagagacg ttcgtgttcc caacggacta
     2161 tcgaaagata atctgacgcc tctgcccaca aatccaatat atgtctttgc taggccggct
     2221 gtggagtcac aaaaataaga cccgtgtaag cttacagggt gtgtgatatt cggcattaca
     2281 tccatgcgtc catcatctcc agttcagcat tattgtaaat ccatgtaaat ttcgatgcga
     2341 gactagcggt tttattttta tcagtcttca aaagacactg aaaactattc attgaaagag
     2401 cgcaaaaata tttctctcca gagtctttaa cttgtaatgt agtagacaac atcaatatac
     2461 aggacctaca ccttgttgat caagttctcc cgctcaatcc caaacgtctt gtccaaccag
     2521 gcgaacattt cgtagtgaac gagtgcaaga gctccgattt tcgcttgtaa accacctccc
     2581 ttgaccccat ttccaatcca aagtcgcttt tgagtgtcgc tgagacaggt caaaccctcc
     2641 ataatcttgt gtgcattttg atctggagtg aagtagaaag agtccgccgc accagtaaca
     2701 agcgtcgggc acttgatgtt ggataagact gcgttttttg tactgtgcag agtgaacttt
     2761 tgcatgaatc tcaagacatc ggccggagtg tcgacgccgt acacccactt gctgtgccca
     2821 aattcccagg ccagttggaa attcaccctt tcaagacacc caatgaccga attgacgaat
     2881 ttgtcactca gccagccgct cagccagcca ttgataaacc aagccggcat acggctcttc
     2941 gtaatttcaa acaagtcgaa ggggccgtcc accgtaatac aggccttaat ccgggcatct
     3001 gttgcagccc gtagagacag atatccgcct agggaagctc caaagacaga gagccgatcc
     3061 aggtccaagt catactctga cgacaacttg tcaaccacaa agtccaagac ctgtcctgta
     3121 acatgctccc agtctggtcg gaggtacagc ttcttttcgc ggagagctcg accttggcct
     3181 gggccgtcaa aggtcagaac agcatacccg cggggcaatg caccagcggc gccgtaaaag
     3241 tacaactctt cctgggtaga gtcgaagcca cctgtttgga caatcaatgg cagcttttgg
     3301 gtgactctgt gttgcgccgc aggaagatac agcctccccg ggagagtctt gtcattgtcg
     3361 tacggaatct ctacctctcg aacatccgcg tcaagcagca cccagccttt attgaaagcg
     3421 tcgacgctcg cccgagacgc agcaagaatt cgagggtcgt ttggcgtgca atggagcaag
     3481 aattcactgg cgcggaagta attggcagat cggatgtacg cccaactcgc tgctgtcttg
     3541 tcgcccgtct ttgctgcgtc ctcagcctgg gaaagtactt cctgtcctat atcccaccag
     3601 gcttgatacc aggtctccgg gtcgccgtcc ttgatcctag acgctgtttc gagacattcg
     3661 ccaacttcgg ccccgtagta tgggaccgtt ccgagaaggc gaaggaactc aaaattgaag
     3721 aaggtggaag ggaagacttg acgcatttgg accacacgtg cacaatctaa tggattagaa
     3781 gaaaagtagc agaacggggc accaaggtct ttctgaatgt gtatcctata actcttgttt
     3841 ctctgtacgg agtttacatg aactatccag gagttgtgtg caccgggggc actttgagtc
     3901 tttcggcgac tttccaactt tcggcgtgat acgacaacac cgatagatca tggttacttg
     3961 actttagatt ctagaagcgc caatttatag ttattcccgt gcttcccttg tcgcgatcat
     4021 gatgtattac tcaggaggtc attcgtccac gacaagcagg tagctcaacc actttccacc
     4081 tattacacat cactcgttta cgcctgacca tccctcttgt atacgaagac ttcttttcaa
     4141 tacaaattct atcagaatgt cacaaaatag cattgtccgg gaaccaatag cggtggttgg
     4201 tgttgcctgc cgcttcccag gggaagcaac cagcccatca aaactctggg acctggtttg
     4261 cgagaagaga gacgtccaga agcccatatc atcagataga ttcaattctg atgcattcta
     4321 caacagtaat ggagaagcta gtggctgcac ggacgtgaaa agggcttatc tgctctccga
     4381 agatatacgg ctattcgacg cctctttctt cagaaccaat gcactggagg cagaggctat
     4441 ggatccacaa cagaggttgt tgcttgagac ggtgtatgaa gccattgagt cggcaggact
     4501 tccgttggaa gatcttaagg ggtccgatac ggccgtgtat gtcggtagca tgacgggcga
     4561 ctatcacgag atgcttctgc gtgacccgca ggacatgccc aaatacatgg caacgggaac
     4621 ggctcgaagc atactgtcaa atcggttgtc ctacttcttc gactggaaag gtccctctat
     4681 gacgattgac acagcgtgct catcaagtct ggttgctgtt catgaagcag tcacagccct
     4741 gcgactaggt gtatcgacaa tagcttgtgc tgctggagcc aacttgatac ttgggcctga
     4801 gatgatgata tccgagtcta acctacatat gctgtctcca acagggcgta gcagaatgtg
     4861 ggatgcttcg gcaaacggct atggccgagg tgaaggaact gccgcagtca taatgaagac
     4921 gctgttgcag gcattgaagg atggggatta catccatgga atcatcagag aaactggggt
     4981 caattcagac ggtcgcacga acggcatcac gttgcctagt tcagaatcac aaacggcttt
     5041 gataagacag acgtacaagg cggccggcat tgatctcgca ttggagcggt gccagttttt
     5101 cgaggctcat ggaactggaa ccccagctgg cgacccgatc gaagctcgcg ctatatacga
     5161 agccttcttt gacggtgagg agtccacctc caataccaca ggcaatatat atgttggatc
     5221 tgtcaagagc acaatcggac atttggaggg ttgtgccggt ctcgctggcc tcatcaaaac
     5281 tatggaggct gtgcgaaggg gaactattcc accaaacatg ggtttcaaga aactgaatcc
     5341 caagattgaa cgtttctcaa agaatcttat tgttcctacc gaagctctcc catggcccga
     5401 gttgccagag ggcacacctc gtcgagccag cgtcaactct tttggctttg gaggaacgaa
     5461 cgcacacgcc atcatcgaaa actttgaggc agctcaacat ggtcaatctc ctcgtgatat
     5521 tattgtcacc cctgtcgttc tgtcggccaa ctcggaaaaa tccctccgag aacaggctat
     5581 tcaactcaat gccgccatgc aactggcgga tgagagtcgc ctgcgcgaca tcatgtacac
     5641 gttatcacat agacgatcac agctaccatt aaggacattc tttgtgggac actcggctga
     5701 agaagtcaag aagagcgtca aggatgccct agcggaggat ggtacgttta cagtacacaa
     5761 ggatgagaag ccctctcatc agccgagcag aatacttgga gtcttcaccg gacagggtgc
     5821 gcagtggcca acaatgggcc gtgaaatcct gaaagagtcc aaatttgctc aggaagttgt
     5881 caagacacta gagcaatcgc tggcaagtct cccagagcct cctacatgga cactctcgga
     5941 gcaaatattt gctgatgctg ctgcatctcg cctcagcgag gcagaagtat cacaacccct
     6001 atgcactgcc gtgcagttga tgctggtaga gatgcttcga gccgccggaa ttcaattcag
     6061 cggcgtcatt ggacactcat caggcgagat tgcggccgcg tactgtgctg gattcctttc
     6121 cgcctcggat gccattcgtg tggcgtacta ccgcggtgtt tgtgcaaagc ttgcaaaggg
     6181 cagcaatggc aaatccggtg ccatgatggc agttggtctg tcctatgaag aagctctgca
     6241 gttttgcaac aatgagtttg attcaagact tgatgtcgcg gctagcaatg cgcctgccag
     6301 cacgaccatc tcgggagacg aagacgccat ccaggaagcc aaggctctct tggaccagag
     6361 gagcatattc gcccgagtgt taaaggtcga cacagcctac cattctcacc acatgcttcc
     6421 ttgtgccggt ccctactcaa gtctactgaa agagtgcggc gtccggagct tgtcgggtaa
     6481 ccctgcttgc gaatggtatt cgagcgttat ttgcgaacgt atcgacggca ctaggcatga
     6541 cgggattcta ggagccgagt attggagaga caatatggtt aacgcggtca agttttcttc
     6601 tgcggctgaa ttggcgatac aaagcggtga agactttgat gtggtattgg aagtcggacc
     6661 tcatcctgcg ctcaaggggc cttttgagca aactgtcaaa caagtatccg actctacacc
     6721 accatatcag gcaactttga tgcgaaatat ccatgatatt gatgccctga gcaaaaccct
     6781 gggatttctc tggtccagat taggcaaatc tgtggttgac ttttcggcat atgcagcctg
     6841 cttcgatgtg ttgcctggac gaatggcgga caacatgcct acatatccct gggatcacgg
     6901 acaatcgttc tggaaggagt caaggaagtc ggccaacttt cgacttcgta cccatcctcc
     6961 tcacccgcta cttggtgtcc gttcttctga agatatgggc cctgaaatga gatggctcaa
     7021 catcttacgc gtgaacgaga ttccttggct cgaagggcac aaagtccagg gccaagtcat
     7081 ctatccggct gctgcgtacc tcgtcatggc gatggaagct gccaaggcta ttgatgagac
     7141 caagttggtt caactggtag aactgtatga tgtgcgaatt ctcagtgcta ttcaactagc
     7201 tcagagctct caaggagtcg agatttcgtt ctctctcaat atcaccgaaa aggacgacaa
     7261 cagcagcgtt gctgaatggg cttgctatac gtccagttct acgaataccg ccaactggaa
     7321 gtgccacgcc aaaggacatg ttcgcgttga atttgcaatg cctgtggacg ggcatctgcc
     7381 gcccagaaac cctcccgatg tgtccttgag tacactagac atggatcggt tttacgagtg
     7441 cttgaccgat attggcctcc aatattctct cgaattcaga agcctatcaa gtgttcagag
     7501 gcgccttgga tatgcgacgg cgagcgtgtc gcacatcgcc actgactttg gcgccaccat
     7561 ccaccctgct ttactagact cttcctttca gtctctgttt gcggcatatt gctggccagg
     7621 agatggaact ctcaactgcc cattcgtacc cacgtacctc aagagacttc gaatcctcaa
     7681 catcggggtg cctgagggcg agccactcgt tattgactcc tatctgacca gtgtcaacgt
     7741 ttcagacatc acctgcgaca ttgacattgc actcacggac aagaacaaac catttgtgca
     7801 gcttgagggt ctcacttgca cttcactcct ccgccacgac cccaaaaact ccaaggagct
     7861 atacacccgg actgagtggg aagttgatgt ccacagtgag attcgtactt tggaggttgc
     7921 tcaatcagat gagcagcaga atctagggct ggttgacctc tgcgagcgtt ttgcttacta
     7981 ctacttgaga aatctggata gagttgttca tcggaaggag gttgaaacaa tggagtggca
     8041 ttatcagcgc gtcttcgagt ggatcgacta tttgtttccg atgatagaaa tgggcaaaca
     8101 tcccacaatc aagcccgaat ggtccgaaga ccaacttcca tggctgatgg agcagaaatc
     8161 ccagtatccc gaccaaatcg accttatgtt gatccaggca gtcggcgaga accttccggc
     8221 tgtggttcgc aagcaaacca cgatgctcga gcacatggtc aaggacgacg tcttgaacag
     8281 gttttataaa gaaggcctcg ggttccaaag agcaaacggc tacatgtcgc gcatttcacg
     8341 acagattgcg catcggtatc ctcggatgaa cattcttgag attggcgccg gaaccggagg
     8401 agcgaccaag ggaattctcc agtcgctcgg cagcaccttt ggcacatata cctttacaga
     8461 cgtatctact ggcttttttg aggccgctgc agagcaattc agtccgtggg ctgacaagat
     8521 ggtcttcaag gccctcaaca tcgagaatag cccgacagag caaggatata gcgaagcgtc
     8581 atacgatcta gtcattgcct ccaacgttct tcacgcaacc aagacgctct cagaaactat
     8641 gaggaacgtc cgtcggctac tgaagccggg tggattcttg ttgcttctag aagtcaccag
     8701 tgacattgtt cgagtgaaga tgatgatgtc gggcttgtct ggctggtggc taggtggtga
     8761 tgacggccga cgacacggtc caaccatcac cgttccggag tgggatacgc ttcttcgctc
     8821 aacgggattc tcgggagtgg acaatacttt caacgacttt ggccacagct ccaaatacat
     8881 gacgtcggtg atgctctcgc aggctatgga tgagagggtc gagttcctcc gccagccact
     8941 ttccagccga ggagattcga ccatggccga ttctctgacc attgtcggcg gcacccaggg
     9001 caacgtggca aatatcattg ctagacatct tgctgattgc catcctcggc tggtcgttca
     9061 gtgtgtggca ggtttcgagg acttcgcgtc ccccctcaac agcacggcca tgaaatcact
     9121 gttggttctg caggatctgg acgagcccgt tcttcaaaaa ctggcttcat ctacgctagg
     9181 cggacttcag aaagcaattg atcagtgccg acaagttctg tgggtgtcaa gcggttgtcg
     9241 caaggataac ccgtttgcaa atatgtctgt tggcctgtgt cgcagcttgt cttcggaata
     9301 tccccatatc aagattcagc atatcgatgt cgagactcgc cttgatcagg gtaccatgca
     9361 ccgcatttcc gaagcagcgc ttaggctttt gcatttggaa aaattgtctg ccgacactct
     9421 ctggtcgttt gagcccgagt tgatcctgga ggataaaaag tggtatattc ctcgactcgt
     9481 gccagatgaa aagctgaacc agcgacttac ttccaccaag atggctgtcc aggtcgacac
     9541 gtctctgaaa gaaaggacag ttgagattgt ttctgaagca tcaaaataca tagtcaccca
     9601 gtctgtgcct tgcatcgatg ccgaacaaca gacgccactg acaaccatca atgtgaccaa
     9661 ggcacttctc catcctgtcg ccacagaatg ccacaaagac tatttcctgt gctacggata
     9721 cagggatagc tgtccggata ttcctgtctt ggccttggcc actgccaatg cttcctctgt
     9781 ttctgttccg gagcactttg tattcgactt gccagcggtt gtgaccgacg gcgctgcggc
     9841 tttgcaacga gcagcatttt cggtggtcgc tgagcaggtg ctcgaggacg ttgatacacc
     9901 tggaacaata tttcttcaca atgaagatca gcgcttctct ttagttgtcc gtcaggctgc
     9961 agccgagctg gggttgaggt gcattgctac gacgtcacag gaaccagcat cttctaccag
    10021 tcaatcaata ttcattcacc ctcatgcatc acagcgagta ttgaaggcct tgattcctca
    10081 aaacgcaaag aggttcattg acttttcaac tgatgtggta gaccaatctc gcttccgaga
    10141 ttgcctccct ccaacatgcc gattctacgc actgaaccac atggttgcga cgggcagcaa
    10201 cgtttctggc atttccgtcc aacaagccat caaggcttta acctctacct tggattcttg
    10261 tctctcaagt actgtgaatc aagtcagcat ctctgagctt catgcccagg ctgctgccag
    10321 attcccctac ggaactgtgg tcgacttcgt cggtgagtcg acgatcgcca gagtacctcc
    10381 gttgcagtcg accaggctgt tccgttgcga taagacgtat cttctcgccg gatgcaccgg
    10441 tggttttggc aaggcgctgt gcagatggat ggtagcttct ggcgtgcggc atctggcgct
    10501 gacgacacga aatatcagcg ctgtggacga ggtgtgggtt agagaaattg agcgcgccgg
    10561 cgcgtgtctc aagctctacc aggttgatgt gagcgataag aatgccttgc aagccgtata
    10621 tgaagatatt ggacgcaaca tgccgccggt tgtcggtgtc gccaatgctg ccatggttct
    10681 ctccgataag tccttcgggg agctgaagac ggacaacttt gacattgtgt ttggacccaa
    10741 ggtccgtgga actcagaacc tgcatgatat cttcaagggt caggctttgg acttctttat
    10801 catgttttct tcccttgcca gtgttgttgg taatcgaggc cagtccaact acgccgctgc
    10861 caacctgttt atgaccacga ttgcagagca gcgtagagca agcaatctgg ccgcttccgt
    10921 tattcacatt ggcatggtcc tcggcgttgg ttatgtttct tccacgggca cgtatgaaaa
    10981 cactttgcga cagtacaact acatgcccat ctccgagtcc gacttcctca acatgttctc
    11041 tcaagccatc ttgatcggac acccgaggtc caaccacccg tgcgaactaa tcactggcct
    11101 caatcggtac agtctcaatt cggacgccca gcagtacttt tggcatgaga acatgcggtt
    11161 cagccatcat tacatcgaag aagaacagcg aaaagtctca acggccacgc gaacctctgt
    11221 atctgagcgc ctggaggatg ctcgggggag cgaagaaatt ctagctgtga ttgaagaaga
    11281 attctgcaca aagttggagc gcatgctcca ggctgaagct ggtaccatca aagcttccca
    11341 gtctctcgcg aacctagggg tggactcctt agtagcagtt gaaatccgat cttggttctt
    11401 caaagaagct gacgtggaca ttccagtatt ggacgtcctc aatactggta ctatttcgga
    11461 gctttgccaa cgggctgcgc aaagcgtcgc ggcggctcag ttgtctgatg ctgaagagtg
    11521 tgccaaaccg gacgataagg tatgttactc tcaggatatg ttggagaaga gtactaactg
    11581 atctctctgt gatgtagtct cccattctgt tgtctgcaaa tataccagaa agcaacgaat
    11641 ccactgcggc aaacacatct gttccgcatt ctctttttga agagtcgtct cgagggggta
    11701 gtgagactcc aagtgaggat atgggtagtt ccgatattag cttaccctcg agacgcgact
    11761 tcgaatttga acggtgcggt cggctgtcgt tcgcccaaga gcgactgtgg tttctacaaa
    11821 aatacctcca agatcctacg acctacaatg tcagtatggc ttacaagatt tctggcccgc
    11881 tacgacggag agactttgaa gatgccttcg aaaaggtcat ccagcgtcat gcatctttgc
    11941 gtaccggttt ttacgtcgat gccgatacta gcctcccaat gcagcgcgtt tacaaatacc
    12001 cccatttccg tttcacgcac aaagaaggcg ctgattatga ggaggagtat cacaatatgc
    12061 agaagatgcg gtatgatttg gagagcggtg acgttataag tgccacgatt ataaggtaca
    12121 ctgaccaaga gcacgttttt attcttggct tccaccacat tgccatggat ggatttagcg
    12181 cccaaattct cgtcaaggat ttaattgacg cctatggagg actcacgata tcctcaggtt
    12241 gcaatgaata cctggactac gctatccatc agcgagatgc tggtatcccc gttgagatca
    12301 gcaagttttg gatgtccgag ttcaacactc tgcctccggt tctccccctt ttcgactttg
    12361 ccgaatgtaa aactcgcaca cctcttcttg actacaagac aaaagcggtc gaaaggacag
    12421 ttcccacgac ggtgtcttcc aaagtgaaaa tcctggcacg gcaacttggt gccacgccat
    12481 ttcacatcta cttggcagct ctgcaagcac tgttatacga tataaactcc aacaaggata
    12541 tttgcatcgg tatcacggac gcgaacaaga ccgatcctgc ctatctagat accatcggtt
    12601 tctttgtcaa tcttgtgcct attcggttcc atattgatga atctgaggca gtcttggagc
    12661 ttgtagctag atcgaagaag accgccacca atgccttgtc aaactcgatg ccttttgatg
    12721 ttctgttgga cgatctgcag gttcctcgtt ccacaactca cagcccacta ttccaagtca
    12781 tcctgaacta caagatggga tcaacacaaa cggttcgttt tgaagactgc gaagcggaaa
    12841 tattaagatt cccaggtgcg agcaacgcct ttgatttggc ttttgacatt ggaaacttcc
    12901 ccgacggctc cgcctccatt tctctcaaaa ctcaggcata catgtacact gacttggagc
    12961 tgcggttcat tcttgacagc tacattcgca tcctgagttc tttcgtgtca aatccttcgc
    13021 agaagcttca cgaggtaact gcactgtcag aagacgaaaa ggagaaatct ctacaactcg
    13081 ggagaggcag gcaactccca gacccgaggc tcgaaacggt cgcccacttc tttgaggact
    13141 gggctttaac tcagccactc aagattgcgc ttcgagaaga ttccggagcc gagttcactt
    13201 acaggcagat tcagtctatc gtgaacgcct ttactgaaac gctgcatggt gctggccttg
    13261 gtccaggctc aaaggtgtgc gtctattgcg agccgggcac tcatattctc gcggctctgt
    13321 tggcgatttc caagattggg ggaatttaca ttcccctcga cccgcagaat cctacagagc
    13381 gcctgcagct cattgtcaac gactgcgaac cggacgcaat actttgcgac gatgttacaa
    13441 gcactctggc atcgcttctg aagtcggcag gaaagtcgat caacgtcacc gacattgata
    13501 caagtgctac tactacatct atccctgact ggaacaaggc caagggtgat tctgcggcat
    13561 tcgtattcta caccagcggc actacgggcg tgcccaaggg aatcgccttg acgcactcga
    13621 atgtcgtaca tcacatcaac tccatcatgc acttttacag catcaagagg ggtgtcgtcc
    13681 ttcagcaagc cccccttgga tttgacatgt cgcttacgca aatgactctg accatgatga
    13741 cggggggcac cctggttgtt gcgtctagtg cgacaagaag agatcccagg cagattgcca
    13801 gtttgatgta cgcaaacaag gtaacgcata catttatgac acccacgcta gccctagctc
    13861 tcatccgcca cggttacgat gccttggcgc gatgttccga ctgggagttt tcgttgcttt
    13921 ccggcgaggc attccgagcc catgtcgttc acgagttcag acgcctcgga cttgctggtt
    13981 tgaagctcta caacgggtac gggccgacgg agattacgat caacagcagc agtggtatgg
    14041 atgagcttga cgaagcggcc ccccgagaca cacggaaccc atccatcgga gccacgttgc
    14101 ccaactacac caactacata ctggataaga atatgcagcc agtacgcatt ggcaatgctg
    14161 gtgagctgtt tgtgggcgga gccggcatcg ccctgggtta cttgcgaaga gacaaactca
    14221 acaaggaaaa gttcctgccc gacccatttg ccagcgcgga taaccgagct cgaggctggt
    14281 gccgcatgta tcggacggga gacaaggcca agtttctgcc tgacgggcga atcgttttcc
    14341 tcggtcgtat ccaaggcgat tctcaggtca aacttcgtgg cttccgaatc gaactagtgg
    14401 acatttccaa caccatcatc aagagttctc atggaaatat tacagaggcc gggatttctc
    14461 tgcgccggaa tggaaacgga tcggatgatg agtcgttctt ggtcgcattt gctgtggtat
    14521 cacactcctt tgaccacccg gaaccgtcgg cattcttcaa gaaactgctg aatgatttgc
    14581 aactaccaag gtacatgatt cctgccaaga ttgtaccggt ggaccgactg ccaatgagct
    14641 cttccggcaa actagaccaa aatgtgctcg acagtcttcc cgtgccaaag gaagaagaga
    14701 gcaaccagag ccccttgaca gatacgcagg agaggctcaa gaagctctgg gtggaagccc
    14761 ttccgcctat tggagcgacc gccgtcatcg accaagatgt tgatttcttc caggttggtg
    14821 gaaactcgct gcgaatcatt ctgctgagag aatctataag cagggagttt tgtgtctcgg
    14881 tgtctgtctt cgatctcttc gcaaacagca ccctgggaag aatggctgcc aggattgacg
    14941 agtctaccga tactactaca agccccgaaa ctatcgactg gaacacggag actctttttg
    15001 atgtccccgt catcgaaacg tgcgaggacg atagttataa acaacacagg gctacatctg
    15061 atgggcttga gatcattctt actggagcta ccggattcct ggggtctgcc attctcgcgt
    15121 cccttgtcca agatgccagg gtatccaagg ttcactgcgt ggccattcga caacccctga
    15181 agagtctcac ggcggaacag ccaatcttca aatctcctcg cgtgagctgc tatgccggtg
    15241 acctatctct gccgcgtctc ggactatcta cttctgactt cacccaactg tccgccaata
    15301 ctgacaagat catccacaat ggagcggatg tttcgtttct gaaatcatac caatccctac
    15361 gagccaccaa tgtgggttcg accaaggaga ttgtccgcat ggcagctctg caccgcattc
    15421 cgatccattt catctctacc ggaggcctgg ccaacttgac aaacctggat ggcctgcccc
    15481 aagtttccgt ctcgtcgttt acgcctccgg tcgatggttc gcagggctac attgccacca
    15541 agtgggcatc cgaagtctac ttggaaaatg tcgtgacacg cctaggaatt ccggtttgga
    15601 tccatcgccc atcaaacatt accggcatcc gctctccctc tgtcgacctg atgcagataa
    15661 tctttaaata ctcggaacaa atcaaggccg tgccggaaat tgacggctgg aaagggtgct
    15721 ttgactttgt tcctgttgaa acggtagccc ggggaatcgt ttgcgcaatc cacgaacccg
    15781 gggtgcagca gggtacgagg ccaatttacc gccaccactg cggccgtgac aagattccag
    15841 tcactggcat tagagagcac ttggaaacga aggtgggagc tcgaatcgac agtgtcggaa
    15901 ttgaggagtg gttgagtcga gctcaaagtg tcgggctgga cgacactgca gctgctctcg
    15961 tcagtagcac ctttgctcaa agcagcacca agactgttcc ttggctaaga agtggtgact
    16021 gaatcgacgt ttggaagatg tcctgacttt ttgttgttat tttttttttt ttggcgtcct
    16081 ggggtatttt agaaaaggtt gtatagggaa ttcggagttg atgtttctcg cacaaggacc
    16141 ttgagttggt tggatgaaat tatgagatgc agtttcattt gaatcaattg aatataaaat
    16201 actaaattat aagaaaaata aaagaaaaag gcgacatagt tacacgggtt ccactagtaa
    16261 cacaatcaat aagcccgtgt cangctctga cgacagtaac tcgcattaaa aaaaaacact
    16321 gaccgcatcg cgctgcgtta aacgcactag ctcaggtggt gattcgtgac cgcacgcgcc
    16381 ggcgacagcc atctgacggc ctcggccact tgaagcgtgg aacaaaatgt tgaatataaa
    16441 atatgaaatg aaatatcact acaggacata tctagggaaa tgtagagtgc acgaaaatgt
    16501 ccgcattgaa acaaataggg agccggggtc ctaccctata gttcgatgtc agtttaactc
    16561 gtcggatcat cggcagatga ggtttggcga cgaacacatt ccatggatca aagaaattag
    16621 acaacttgaa ttcataggag atgatacaag acctgaaatc caaataccat gactcgcatg
    16681 ttcctctcag ctaatgacat agtgtctttc ccgccgccac catgaatgcc ccccacgcca
    16741 gcaagtcgac agtccaagtc cgaacattgt tcacacggag ccattcatcc aggcagtcgt
    16801 tggcatccgt ctgctccttc ccgtccatca tatctttgac actgggcgca atcagcggga
    16861 cgaatagcaa atgacttgcg gcggcgattg tcccagcagc gtaccaccaa tacgactggc
    16921 gagattgcaa gacggaacgc tgtgcgaaaa ggttgccgac accgctccag gtcgatacgc
    16981 caatggcgcc aaccacaaag ggcagaccac ggtaaaaaaa ggtgttaaag tacgactgca
    17041 gcaggggttt gcttttggcg cggttctcgg gtcggttcat gattcccagg aagaatgttt
    17101 ggtcccagcc aaagagcagg gtgcacgtcg acgagaccag aggcagcgcc cgcaacgcca
    17161 ccaaggggtc gaaaaaggct cccgaagcca ttcttgtccg tctgactaga ttttcttgcg
    17221 ttggtcgaaa tggtgcagaa gcaaaggggc cgcagagagt gcggcaattt gttgtcaatt
    17281 ggattgacag attgtgcaat cccatggttt tcggcgcatt gtgttcggcg actttcggag
    17341 tcatacgaca gtatattgtc agcagtctgg cgactggact acatgctctt ccacccacga
    17401 catcatgttt ctccatactt tgccaagagg gcccagatgc atcacgacac catggcgact
    17461 gatatcaatg tcctcgcggg cggcgcagcc gtcgacgccg ggtcgcaaac gaacaagaaa
    17521 ggactcaagt tctggctagt ttttgcagcc atttctctga caacctttct cgccgctctc
    17581 gacacatcca tcatctcaac tgcgctgcct accattgcgg ccgaccttgg gtctgagagc
    17641 ttgtatgtgt ggatcataga ttcgtatctg ctggcctcga ccgctacgat tcccatattt
    17701 gcccaggctg ccaacatcta cgggcgacgc agcctcatac tcatttcggt gctgctcttt
    17761 gcgcttggaa gcggcctctg tggcggcgcg tccaacaatg ccatgatgat tggtggacga
    17821 tcagtccagg gcgtgggcgg cggcggcatt ctgaccatgt cagagattat cgtctgtgat
    17881 ctcgtctcca tccgtgagag gggtctttat gccggtatta tcggaggcat ctgggctgtt
    17941 gcttccgtca ttgctccaat tataggcggc gcgtttgcac aaaacatcac ctggcgctgg
    18001 atcttctaca tcaatctacc catttctggc gtctccatca tcgctttggc gctgttcctc
    18061 cagctacgcc ggcctcctgc tggcaccatc aaaagccaag ttgcgcgaat agactggggc
    18121 ggtagttttc tgctcataac gtccattacg gccatcattc tggctcttag ctggggaggt
    18181 tcgaccaacc cgtggtcttc ttggaggacc attgtccctc ttgttctggg cttcattggc
    18241 cttgtattct tttttgtgta ccaggcggcc ccttggttga cggatcttac gatgccgctg
    18301 cgactattcg gcaaccgcac agccgtcaca gtcttcataa tgagtttcat ccatagcatg
    18361 ctactgttct gggtctgcta cttcctgcct gtttactttc agggtgtcaa ggaagctagt
    18421 ccatctcgat ccgccgtcat gctattccct attgcaacaa ccagtgctcc aggtggtgtg
    18481 attgcgggta tttccatcac aaaaaccgga acatatcgta tctggcactt tctcggattc
    18541 ggcctcatgg cgttgggttg cggtttattc actctctttg atgaaaccac tcctactggc
    18601 cagtgggttg gcttccagct tctctttggc tttggttgcg gttttgtctt caccagctgc
    18661 ctgcctccca ttctggccag tctacctgat tcagacgttg caacagctac aggtgcctgg
    18721 acatttcttc ggaactttgg ctctatatgg gggattgcta tacctgccgc cgtgttcaac
    18781 acacatgcta acaaattcgc ctctgaagtc tctgatccga gtgtgcgggc ccttcttgtg
    18841 aacgggggag cttacggcca tgccacgcgt gaattcatta ccatgtttga cggagaccct
    18901 gccctaaaat ccgaaatatt gagcctctat attcgggggc tcaaagtcgt ttgggaagtg
    18961 tctattgctt ttgcgctccc ttgggcctgg cttttgcttt ctttgtttcc atccatagag
    19021 ctcagagacg agttgaacac tgagtatgga atgaaagaag cagagacgaa acctactacc
    19081 gacctcggcg acaaggcttg agcacgctag tgtgacatgg cgtggcagaa gaacgtgcat
    19141 ctgctatggc agtattcctc caccataaac ggggtctttg gttcttccat tcagaatagc
    19201 ttgcattgta atgaaacaca acatgtcccc tgcgtgaaat ccggtgtatt gttattcaat
    19261 ggtaatggcg agtatgtatc ccgacaagtt gaaacaacat ctcagattcc cgagtgtatg
    19321 tgatagggtc agtaaacaca gatggtacta gtggcagagc aaatatgagc gaggtctttg
    19381 ttagtgaagg ggtcgccgtt gtaattattt ccacaacttc aggaatccgt gttggactcc
    19441 aagttgccga atcaaacctt tcgattcatc tcatctgtta ttttacgtcc atgttcaact
    19501 ttgactcttg gataaaaagc tgtatctgtt tctggtccca ccaacacaaa ctacaggttc
    19561 gccgggctca ctgctcaaaa gtcgccgaac attaattaaa atcctacaag ttggctcacc
    19621 ggatttcacc atttgccacc agaggttgcc atcattacct agcatcatca atggaccttt
    19681 ctgcgttcta caacattgtg gccggtgagc tgcgaggctc cgagaatacc acaacgcccc
    19741 gtaccgcagc ctctctccca gcatgcccag cggctattgc aagcgacgtc gaggatagcg
    19801 ttgctgcagc gcagaaag
//
