Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001042.1:
Cluster 1NRP / Polyketide1118372

BGC0001042, sanglifehrin A biosynthetic gene cluster from Streptomyces flaveolus. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: sanglifehrin A
PubChem ID: 5388925
SMILES string: Copy to clipboard
Molecular formula: C60H91N5O13
Average molecular mass: 1090.41 Da

Class-specific details

Biosynthetic class(es):
NRP / Polyketide
Polyketide synthase subclass:
Type I

Gene cluster description

Download cluster GenBank file
sanglifehrin A (BGC0001042). Gene Cluster 1. Biosynthetic class = NRP/Polyketide. GenBank FJ809786. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Qu X et al. (2011) Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor. Mol Biosyst 7(3):852-61.