BGC0001044 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001044 (Plenodomus lingam (Leptosphaeria maculans))

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS,indole	1	48,076	sirodesmin PL	NRPS:Type I	100%

BGC0001044 - Region 1 - NRPS,indole

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Location: 1 - 48,076 nt. (total: 48,076 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
indole: (indsynth or dmat or indole_PTase)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 48,077
Label		BGC0001044

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001044	1.05	NRP	sirodesmin PL	Leptosphaeria maculans
BGC0002736	0.32	Terpene	preaspterpenacid I	Aspergillus terreus NIH2624
BGC0002321	0.32	Other	pulcherriminic acid, pulcherrimin, cyclodileucine, compound 3	Metschnikowia aff. pulcherrima
BGC0001989	0.31	Other	pulcherrimin	Kluyveromyces lactis
BGC0001636	0.29	NRP	KK-1	Curvularia clavata
BGC0000457	0.28	NRP	vicibactin	Rhizobium etli CFN 42
BGC0000685	0.27	Terpene	brassicicene C	Alternaria brassicicola ATCC 96836
BGC0001547	0.26	Terpene	citreohybridonol	Aspergillus stellatus
BGC0001873	0.25	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0001791	0.25	NRP	sunshinamide	Gynuella sunshinyii YC6258

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001044	1.00	NRP	sirodesmin PL	Leptosphaeria maculans
BGC0002736	0.65	Terpene	preaspterpenacid I	Aspergillus terreus NIH2624
BGC0002226	0.65	NRP	acu-dioxomorpholine B, acu-dioxomorpholine A	Aspergillus aculeatus ATCC 16872
BGC0002321	0.65	Other	pulcherriminic acid, pulcherrimin, cyclodileucine, compound 3	Metschnikowia aff. pulcherrima
BGC0001989	0.65	Other	pulcherrimin	Kluyveromyces lactis
BGC0000457	0.63	NRP	vicibactin	Rhizobium etli CFN 42
BGC0000688	0.61	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0000685	0.60	Terpene	brassicicene C	Alternaria brassicicola ATCC 96836
BGC0000811	0.60	Alkaloid	fumigaclavine C	Aspergillus fumigatus Af293
BGC0001777	0.60	Terpene	shearinine D	Escovopsis weberi

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 48076:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 0 - 40401:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

sirP

AMP-binding (50..434): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAGPFGCCTK
Nearest Stachelhaus code(s):: Trp DVGPFGACTK (68% 8Å match)
Stachelhaus code match:: 80% (moderate)

AMP-binding (1093..1474): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DCNMAAVISK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)