BGC0001044

BGC0001044: sirodesmin PL biosynthetic gene cluster from Leptosphaeria maculans

Download region SVG

Location: 13,885 - 61,960 nt. (total: 48,076 nt).
This entry is originally from NCBI GenBank AY553235.1.

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

General

Compounds

Genes

History

NRPS/PKS domains

KnownClusterBlast

General information about the BGC

MIBiG accession	BGC0001044
Short description	sirodesmin PL biosynthetic gene cluster from Leptosphaeria maculans
Status	Minimal annotation: yes A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s) Completeness: Unknown Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)	NRP
Loci	NCBI GenBank: AY553235.1
Compounds	sirodesmin PL
Species	Leptosphaeria maculans [taxonomy]
References	The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus Leptosphaeria maculans. Gardiner DM et al., Mol Microbiol (2004) PMID:15387811 A tyrosine O-prenyltransferase catalyses the first pathway-specific step in the biosynthesis of sirodesmin PL. Kremer A et al., Microbiology (Reading) (2010) PMID:19762440 A Zn(II)2Cys6 DNA binding protein regulates the sirodesmin PL biosynthetic gene cluster in Leptosphaeria maculans. Fox EM et al., Fungal Genet Biol (2008) PMID:18023597 The ABC transporter gene in the sirodesmin biosynthetic gene cluster of Leptosphaeria maculans is not essential for sirodesmin production but facilitates self-protection. Gardiner DM et al., Fungal Genet Biol (2005) PMID:15707846

Chemical products information

sirodesmin PL

Copy SMILES

C₂₀H₂₆N₂O₈S₂

Chemical database entries
PubCHEM

List of genes involved in compound(s) production

Identifiers	Position	Product	Extra
AAS92539.1 sirH	13885 - 15208 (-)	SirH	copy AA seq copy Nt seq
AAS92540.1 sirQ	16247 - 17624 (-)	SirQ	copy AA seq copy Nt seq
AAS92541.1 sirI	17859 - 19217 (+)	SirI	copy AA seq copy Nt seq
AAS92542.1 sirJ	19492 - 20988 (+)	SirJ	copy AA seq copy Nt seq
AAS92543.1 sirR	22244 - 23666 (+)	SirR	copy AA seq copy Nt seq
AAS92544.1 sirB	24755 - 26753 (-)	SirB	copy AA seq copy Nt seq
AAS92545.1 sirP	27464 - 34285 (+)	SirP	copy AA seq copy Nt seq
AAS92546.1 sirG	34508 - 35380 (+)	SirG	copy AA seq copy Nt seq
AAS92547.1 sirC	35962 - 37838 (-)	SirC	copy AA seq copy Nt seq
AAS92548.1 sirM	38262 - 39577 (+)	SirM	copy AA seq copy Nt seq
AAS92549.1 sirE	41016 - 42503 (-)	SirE	copy AA seq copy Nt seq
AAS92550.1 sirS	43832 - 45355 (+)	SirS	copy AA seq copy Nt seq
AAS92551.1 sirZ	45596 - 47295 (-)	SirZ	copy AA seq copy Nt seq
AAS92552.1 sirA	50589 - 54945 (+)	SirA	copy AA seq copy Nt seq
AAT01502.1 sirN	55331 - 56367 (-)	SirN	copy AA seq copy Nt seq
AAS92553.1 sirO	57036 - 58269 (+)	SirO	copy AA seq copy Nt seq
AAS92554.1 sirD	58737 - 60134 (-)	SirD	copy AA seq copy Nt seq
AAS92555.1 sirT	60918 - 61959 (+)	SirT	copy AA seq copy Nt seq

Annotation changelog

MIBiG version	Submitter	Notes
1.0	Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).	Submitted
2.0	Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).	Migrated from v1.4 Updated compound(s) information
3.0	Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).	Removed incorrect polyketide class

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters