LOCUS       BGC0001045             54335 bp    DNA     linear   BCT 19-NOV-2013
DEFINITION  Pseudomonas sp. Q71576 spiruchostatin biosynthetic gene cluster,
            complete sequence.
ACCESSION   BGC0001045
VERSION     BGC0001045
KEYWORDS    .
SOURCE      Pseudomonas sp. Q71576
  ORGANISM  Pseudomonas sp. Q71576
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:45:24
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 54335
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..54335
                     /db_xref="taxon:1231908"
                     /isolation_source="Japan"
                     /mol_type="genomic DNA"
                     /organism="Pseudomonas sp. Q71576"
                     /strain="Q71576"
     subregion       1..54335
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001045"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..54335
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..52109
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[6630:32109]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6631..32109
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..52109
                     /SMILES="NC(CS)C(=O)NC(C)C(=O)NC(CS)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     CDS             2300..3715
                     /codon_start=1
                     /note="orf-1"
                     /product="putative protease PrtA"
                     /protein_id="AFR69327.1"
                     /transl_table=11
                     /translation="MSKLKENAFSAIGQASKAYDQVDGFSHRYDRGGVDLVNDKPSFTA
                     DQAADELLRKGASWHDQNGDGKISLSYTFLTSQPADFNPGLGTFSEFSALQKAQAVLAL
                     QSWSDVANVTFVDAPGGVDGQLTFGNYSSFAGGAAFAYLPTGGSRDGQSWYMVNDQYPT
                     NTTPDNGNYGRQTLTHEIGHSLGLSHPGNYNAGNGSPTYNDVTYAEDTRGYSLMSYWSE
                     SNTQQNFSGAYSSAPLMDDIVAIQKLYGANLDTRDGNTVYGFNSNTGRDFYTANTSSDK
                     LVFSVWDGGGNDTLDFSGFSQNQKINLTAGSFSDVGGLVGNVSIAHGVTLENAIGGVGD
                     DLLIGNSAANILEGGAGNDILYGGGGGDTLWGGAGADTFVFGQASDSTMTAPAWIMDFT
                     SGEDKIDLSGLFASVGATLNIVTGFTGHAGDAILTYFQQTNQTSLMVDLTGSGLVDFAV
                     GTVGQAAMTDIVA"
     misc_feature    2300..46709
                     /note="spiruchostatin biosynthetic gene cluster"
     CDS             4917..5789
                     /codon_start=1
                     /gene="spiR"
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 109.1; E-value: 4.1e-33)"
                     /gene_kind="regulatory"
                     /product="lysR family transcriptional activator SpiR"
                     /protein_id="AFR69329.1"
                     /transl_table=11
                     /translation="MSRQFDVAVLKTFHAVARFGRFKDAAIYVNRSASAVTVQIHKLEE
                     QVGHRLFHRNNNVVELTPFGRKLLGYTTDFLVAHDRLITSLAPQRLLLKLRLGVPDVYV
                     AKFMKDLLPTFTLSNPMLELEVEARSSGELFDLFSQQMLDITLLVASQCPQDGEFLCST
                     SPRWVVSPAFKYDPGQPLPVSVHLHGCPYREAAIRALKTAGIKFRIFMESSSFTAVEAS
                     VMSGLSIGVMENGLVDRRANRSVQGIELPDLDEHFICLLTNSNSPAAVSLRNAIFEQFS
                     KSEFLLDVV"
     gene            4917..5792
                     /gene="spiR"
     gene            6111..6359
                     /gene="spiN"
     CDS             6111..6359
                     /codon_start=1
                     /gene="spiN"
                     /product="putative type II peptidyl carrier protein (PCP)
                     SpiN"
                     /protein_id="AFR69330.1"
                     /transl_table=11
                     /translation="MLLARVIGLRIHFFSIECDWMSGILLLRCIEFGCVVIWAFDYLLC
                     SRTLYIETRRTVMDLFFMELSPCNQFRLGSAEKYQDL"
     gene            6631..11655
                     /gene="spiA"
     CDS             6631..11655
                     /NRPS_PKS="Domain: CAL_domain (152-469). E-value: 6e-100.
                     Score: 326.6. Matches aSDomain:
                     nrpspksdomains_spiA_CAL_domain.1"
                     /NRPS_PKS="Domain: PP-binding (578-615). E-value: 3.8e-07.
                     Score: 22.5. Matches aSDomain:
                     nrpspksdomains_spiA_PP-binding.1"
                     /NRPS_PKS="Domain: Heterocyclization (647-921). E-value:
                     5.8e-44. Score: 142.5. Matches aSDomain:
                     nrpspksdomains_spiA_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (1088-1471). E-value:
                     3.6e-87. Score: 284.4. Matches aSDomain:
                     nrpspksdomains_spiA_AMP-binding.1"
                     /NRPS_PKS="Domain: PKS_PP (1520-1641). E-value: 8.3e-08.
                     Score: 24.4. Matches aSDomain:
                     nrpspksdomains_spiA_PKS_PP.1"
                     /codon_start=1
                     /gene="spiA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     88.4; E-value: 1e-26)"
                     /gene_kind="biosynthetic"
                     /product="nonribosomal peptide synthetase SpiA"
                     /protein_id="AFR69331.1"
                     /sec_met_domain="Condensation (E-value: 4.8e-11, bitscore:
                     32.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.5e-91, bitscore:
                     296.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.1e-08, bitscore:
                     22.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPPYNEQPRVLPRLSLSEQLMLRADAFPDLLAFASLDQSKGVSL
                     TNADLCERAAAIAYRLAKCTSPGDRVLLSYDHPLDFIPAFFGCCFSGTIAVPVAPRTNG
                     ETVAAILLDCGATIALTAQGGKESSGIDWLQTDDNERRASFMRLADENNPALLQYTSGS
                     TRTPRGVAVTQASLRTTIEDLDRAALHDAQSVMVSWLPYFHDMGLVYGILTPLYCGFSA
                     YLMPPESFIAQPLSWLRAIAAVRGTHTAAPNFAYALCADRAADLLPGTDLSSLRFALNG
                     AEPIRCDSVRRFEAAFAPFGMSSSVVIPGYGLAEATLKVTSGRCGEGTRSRHFEPDALA
                     VGKVVPCHQGVELASCGTSSVGASILIVDPATLVPCKPDVIGEIWVAGQSVADGYWSRE
                     HETLEIFQACLAAGGGPWLRTGDLGFLQQDELFVVGRLKDLIIVGGRNIYCYDLEDSVS
                     ECHSDIRKGRVFAVAVEGEDGEEVLIGAEVRSSCKEGDTRAILARIRTELKTRHDVGAV
                     RIVLLKRGSILRTSSGKTRRAATRDALFRGELQVIADSNGQSAEVDDDILLQIARFVPG
                     AVSEPTSRLIDAGLDSLSAARLAAAIYSRYGVRLKFETLCAASVDSLRRDIANAQSVAV
                     AESLASYSIDFTRPFELSEMQQAYWIGQQSGVPLGSVRPHIRVDFEVDHAQVPSLSLRL
                     AALVTAHPALRMSVQEDGRGIIDRHGYDPIIGHRDLRGLAQQNLAEALSAVRDELAQDN
                     RQALSACFTRLTDTNTLLHLRLGLLAGDLRSVLLLVRELVNGPSLAPGFWGMERRTSPM
                     PLDVREAWLRKVASIAPAPDLPQAMAASDVDTPRFVTCHQELSQELTTALALNAQALGV
                     TLSSICMAAFVDVLRLWSTSPELTINVTCSTRSGLTEQAIGDFTSSILLSLCESHGSFA
                     DLSRAIQQQVWRELDDPCSTGISMLRELSRRNGSPVLMPIVLTSLLSGDPADDLSVLDS
                     IGLMVNVSNPTPQVSLHNILARRDGCLMMMWEYVEQLFPAGMIEAMFASFVDVLTMIAH
                     TPSAVEYPVLAKLPAVQHARHLKANSTNRDRSPRRLSTPFIERATETPDAIAVIFGDQI
                     TTYGDLLQDAEDIAARLQRKGVSRGDIIAAIVEPGPRAVAALIGIGIAGAVYLPIEPSW
                     PLTRIEELLYESKAGYAVVMHSMDLPIPMLQLDEKPGRLRPEPVGGAPSDVAYVIFTSG
                     STGRPKGVVITHEAAANTIDDINERFSVGPADRALCVSSLAFDLSVYDIFGLLAVGGAV
                     VFPERLRDPDAIAQALTAAGVTIWNSVPAVLELLLDVAAPHSSTLRLVLLSGDWIAPAF
                     TARIRQVFTQAEPISLGGATEVSIWSVIHPIVPGDAARVSIPYGAPLSNQQCFVRAPDG
                     RERPDGVAGELLLGGRGLAQAYCGNDAETNRRFFTDQDGNRLYRTGDLARWMATGELEL
                     LGRMDDQVKVQGYRIELGEIEAVAMKAGGISRAVASVVRRRGATVIQLHVLVSQGMPGE
                     VVTSVRAALAHHLPAYMQPHHVGVLDTLPLTANGKVDRSRLPAPPEPRAALPMRGDVLL
                     ETMMMQAYVEVVGIGIDPQQRFFDAGATSLHIVRLRALLESRGIAIPSLADFFSLATIR
                     SIATSSMEGVSANSNQNDIACMRAYKQRLRARRGEL"
     aSDomain        7087..8037
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiA_CAL_domain.1"
                     /evalue="6.00E-100"
                     /label="spiA_CAL_domain.1"
                     /locus_tag="spiA"
                     /protein_end="469"
                     /protein_start="152"
                     /score="326.6"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="NPALLQYTSGSTRTPRGVAVTQASLRTTIEDLDRAALHDAQSVMV
                     SWLPYFHDMGLVYGILTPLYCGFSAYLMPPESFIAQPLSWLRAIAAVRGTHTAAPNFAY
                     ALCADRAADLLPGTDLSSLRFALNGAEPIRCDSVRRFEAAFAPFGMSSSVVIPGYGLAE
                     ATLKVTSGRCGEGTRSRHFEPDALAVGKVVPCHQGVELASCGTSSVGASILIVDPATLV
                     PCKPDVIGEIWVAGQSVADGYWSREHETLEIFQACLAAGGGPWLRTGDLGFLQQDELFV
                     VGRLKDLIIVGGRNIYCYDLEDSVSECHSDIRKGRV"
     aSModule        7087..8475
                     /domains="nrpspksdomains_spiA_CAL_domain.1"
                     /domains="nrpspksdomains_spiA_PP-binding.1"
                     /incomplete
                     /locus_tags="spiA"
                     /starter_module
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       7093..7149
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiA_0001"
                     /evalue="2.30E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="spiA"
                     /protein_end="173"
                     /protein_start="154"
                     /score="17.1"
                     /tool="antismash"
                     /translation="ALLQYTSGSTRTPRGVAVT"
     CDS_motif       7768..7842
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiA_0002"
                     /evalue="1.30E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="spiA"
                     /protein_end="404"
                     /protein_start="379"
                     /score="24.0"
                     /tool="antismash"
                     /translation="VIGEIWVAGQSVADGYWSREHETLE"
     CDS_motif       7930..7992
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiA_0003"
                     /evalue="3.80E-02"
                     /label="NRPS-A_a8"
                     /locus_tag="spiA"
                     /protein_end="454"
                     /protein_start="433"
                     /score="7.1"
                     /tool="antismash"
                     /translation="VGRLKDLIIVGGRNIYCYDLE"
     aSDomain        8365..8475
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiA_PP-binding.1"
                     /evalue="3.80E-07"
                     /label="spiA_PP-binding.1"
                     /locus_tag="spiA"
                     /protein_end="615"
                     /protein_start="578"
                     /score="22.5"
                     /tool="antismash"
                     /translation="SEPTSRLIDAGLDSLSAARLAAAIYSRYGVRLKFETL"
     aSDomain        8572..9393
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiA_Heterocyclization.1"
                     /evalue="5.80E-44"
                     /label="spiA_Heterocyclization.1"
                     /locus_tag="spiA"
                     /protein_end="921"
                     /protein_start="647"
                     /score="142.5"
                     /tool="antismash"
                     /translation="RPFELSEMQQAYWIGQQSGVPLGSVRPHIRVDFEVDHAQVPSLSL
                     RLAALVTAHPALRMSVQEDGRGIIDRHGYDPIIGHRDLRGLAQQNLAEALSAVRDELAQ
                     DNRQALSACFTRLTDTNTLLHLRLGLLAGDLRSVLLLVRELVNGPSLAPGFWGMERRTS
                     PMPLDVREAWLRKVASIAPAPDLPQAMAASDVDTPRFVTCHQELSQELTTALALNAQAL
                     GVTLSSICMAAFVDVLRLWSTSPELTINVTCSTRSGLTEQAIGDFTSSILLS"
     aSModule        8572..11553
                     /complete
                     /domains="nrpspksdomains_spiA_Heterocyclization.1"
                     /domains="nrpspksdomains_spiA_AMP-binding.1"
                     /domains="nrpspksdomains_spiA_PKS_PP.1"
                     /locus_tags="spiA"
                     /monomer_pairings="Cys -> Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       8719..8769
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiA_0004"
                     /evalue="1.90E-04"
                     /label="Cy2"
                     /locus_tag="spiA"
                     /protein_end="713"
                     /protein_start="696"
                     /score="14.0"
                     /tool="antismash"
                     /translation="LVTAHPALRMSVQEDGR"
     CDS_motif       9010..9057
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiA_0005"
                     /evalue="1.20E+00"
                     /label="NRPS-A_a6"
                     /locus_tag="spiA"
                     /protein_end="809"
                     /protein_start="793"
                     /score="1.8"
                     /tool="antismash"
                     /translation="NGPSLAPGFWGMERRT"
     CDS_motif       9238..9297
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiA_0006"
                     /evalue="3.10E-06"
                     /label="Cy4"
                     /locus_tag="spiA"
                     /protein_end="889"
                     /protein_start="869"
                     /score="20.0"
                     /tool="antismash"
                     /translation="GVTLSSICMAAFVDVLRLWS"
     CDS_motif       9355..9393
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiA_0007"
                     /evalue="9.00E-04"
                     /label="Cy5"
                     /locus_tag="spiA"
                     /protein_end="921"
                     /protein_start="908"
                     /score="11.9"
                     /tool="antismash"
                     /translation="QAIGDFTSSILLS"
     aSDomain        9895..11043
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiA_AMP-binding.1"
                     /evalue="3.60E-87"
                     /label="spiA_AMP-binding.1"
                     /locus_tag="spiA"
                     /protein_end="1471"
                     /protein_start="1088"
                     /score="284.4"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="IERATETPDAIAVIFGDQITTYGDLLQDAEDIAARLQRKGVSRGD
                     IIAAIVEPGPRAVAALIGIGIAGAVYLPIEPSWPLTRIEELLYESKAGYAVVMHSMDLP
                     IPMLQLDEKPGRLRPEPVGGAPSDVAYVIFTSGSTGRPKGVVITHEAAANTIDDINERF
                     SVGPADRALCVSSLAFDLSVYDIFGLLAVGGAVVFPERLRDPDAIAQALTAAGVTIWNS
                     VPAVLELLLDVAAPHSSTLRLVLLSGDWIAPAFTARIRQVFTQAEPISLGGATEVSIWS
                     VIHPIVPGDAARVSIPYGAPLSNQQCFVRAPDGRERPDGVAGELLLGGRGLAQAYCGND
                     AETNRRFFTDQDGNRLYRTGDLARWMATGELELLGRMDDQVKV"
     CDS_motif       10282..10341
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiA_0008"
                     /evalue="6.90E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="spiA"
                     /protein_end="1237"
                     /protein_start="1217"
                     /score="33.9"
                     /tool="antismash"
                     /translation="AYVIFTSGSTGRPKGVVITH"
     CDS_motif       10846..10935
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiA_0009"
                     /evalue="1.00E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="spiA"
                     /protein_end="1435"
                     /protein_start="1405"
                     /score="30.7"
                     /tool="antismash"
                     /translation="PDGVAGELLLGGRGLAQAYCGNDAETNRRF"
     CDS_motif       11014..11076
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiA_0010"
                     /evalue="5.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="spiA"
                     /protein_end="1482"
                     /protein_start="1461"
                     /score="34.4"
                     /tool="antismash"
                     /translation="LGRMDDQVKVQGYRIELGEIE"
     aSDomain        11191..11553
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiA_PKS_PP.1"
                     /evalue="8.30E-08"
                     /label="spiA_PKS_PP.1"
                     /locus_tag="spiA"
                     /protein_end="1641"
                     /protein_start="1520"
                     /score="24.4"
                     /tool="antismash"
                     /translation="VVTSVRAALAHHLPAYMQPHHVGVLDTLPLTANGKVDRSRLPAPP
                     EPRAALPMRGDVLLETMMMQAYVEVVGIGIDPQQRFFDAGATSLHIVRLRALLESRGIA
                     IPSLADFFSLATIRSIA"
     CDS             11655..16340
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (9-431). E-value:
                     6.1e-135. Score: 442.2. Matches aSDomain:
                     nrpspksdomains_spiB_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_DHt (606-733). E-value: 9.2e-07.
                     Score: 20.8. Matches aSDomain:
                     nrpspksdomains_spiB_PKS_DHt.1"
                     /NRPS_PKS="Domain: PKS_DH (713-863). E-value: 4.3e-18.
                     Score: 58.1. Matches aSDomain:
                     nrpspksdomains_spiB_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1158-1336). E-value: 1.3e-56.
                     Score: 183.3. Matches aSDomain:
                     nrpspksdomains_spiB_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1424-1504). E-value: 1.3e-16.
                     Score: 52.6. Matches aSDomain:
                     nrpspksdomains_spiB_PKS_PP.1"
                     /codon_start=1
                     /gene="spiB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 229.5; E-value:
                     1.2e-69)"
                     /gene_kind="biosynthetic-additional"
                     /product="polyketide synthase SpiB"
                     /protein_id="AFR69332.1"
                     /sec_met_domain="hyb_KS (E-value: 3e-139, bitscore: 454.6,
                     seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.6e-48, bitscore:
                     155.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.4e-14, bitscore:
                     43.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQDIPVDAVAIIGAGCRVPGATTLEQFWSVIAGAEVTIERFSAD
                     VARREGVPETVLSQPGFIGAGGALENIEMFDAALFGIAPSQAACMDPQQRVFLECVHDA
                     LEHAGHGAARGPRVGIWAGSASLDYLADHVLGQLDRSSPNRYLQQWVGVDKDYLAAQVA
                     YRMDFGGPAITVQTACSTSLVAVALAVQGLLNYQCDVAVAGGVSIGLPQRQGYVHEDGS
                     ILAADGACRPFTTQSSGTVFGNGAGAVVLRRLEDALDDGDTILAVIRGAAINNDGAAKV
                     GFTAPGGRGQGDVIRTALQLGEVDGASIGYVETHGTGTAIGDAVELSALMSALGDRQLD
                     GQRCAIGSVKANVGHMNAAAGVCGLIKVALAVQHAQIPPTVGAAHAIDALREGSPYYLP
                     TDLTPWSSPDRRAGVSSFGIGGTNAHVILEASPRRLARVRSTVPLLLVSAREDALRDLC
                     ANYAAFLEADPDLSIEDVCFTAAVGRLPRERRVAFRAEHRGQLISSLKAFAEGRQDANA
                     FFYEEQERRPEVTFAFGDTDNLGAAIDGALVWQARGVVPSVVCGTGAGLFAAAFAAGAL
                     SAEDARSAQAHNAVAPSLLWISAFSGMAIDSVEAVRKELAQVAQSGGDGASAVAATGAT
                     RVLEFGDNALGADVAGVVSFAQGALDAIAGLWTSGIDLDLTKIYSGANRVSLPTYPFQR
                     KRFWIDRAPRYTDSGTSIFLGRRTEAPMLRASFFDAQWSVATLPFLSDHMIYGKVIVSG
                     AALAVMIAEGVREVSKAHEFALHDLRFPAALVIPQGMGRRVQLQLVRDDDGFDATVLTQ
                     DPFEIHATARVETTTTVSVVPSQEVQGIDTPTALLDSWLRDHGVVMGPSFSRLSDIVIG
                     HNDAVCSMRTDAGDDGWLLHPGILDSALQLVAVAARPEGSKAFVPTRIARLTIRAHTAS
                     QVRCYAAADRGLATLFDDHGVLAELVGLESRDVSRNELLRIDPLRDGYSIEWRSSSLDR
                     SFELPQTVVVIRDADGVAEELAAILQAEGKRPLVVGSPSDISFETTDFVVDCRGSDARS
                     TAPDLSVYEGALDLLGTVARKDLPCCVAIVLPVNVPSGAPLQALARVAAMETPYLRTLA
                     VRANNAQSIRRGLDFFDQETEVMVDGDNISAPRFQRFDLPRRTESSFSGDETWLITGGL
                     GELGLRVASWLSALGVRSLVLTGRHSPDTNAQETLTVFGHEGINVQVIQADLSSEADIE
                     ALLHKIDTTMPALRGICHLAGVVEDRLMGDVTPASLKTTFAGKAEGAWLLHERTLHYPL
                     KHFILFSSAAAAFGAPGQAAYAMANAYLDELAVYRRSLGLPALSIAWGPWQDIGMAART
                     AVTAKRRLSQLGIGQIEEECGRATFENILFADLPAHCVLLAVDWQRLVGQWPPQVPFSR
                     FDDIVSDIPGSARTLSVNELLPLSPDERRHRLFQLIAEDVSSITGTDLATLDPERSLFE
                     YDLDSLLITDLRLKFERRFGRPVAATVIFSNPTVAALADHMAQTIFGEVPTDVLRSVAD
                     QAPLPVAVLTEPDNSRPEQLSQEDVVEMLSAKLEELRGGRS"
     gene            11655..16343
                     /gene="spiB"
     aSDomain        11682..12947
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiB_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="6.10E-135"
                     /label="spiB_PKS_KS.1"
                     /locus_tag="spiB"
                     /protein_end="431"
                     /protein_start="9"
                     /score="442.2"
                     /tool="antismash"
                     /translation="VAIIGAGCRVPGATTLEQFWSVIAGAEVTIERFSADVARREGVPE
                     TVLSQPGFIGAGGALENIEMFDAALFGIAPSQAACMDPQQRVFLECVHDALEHAGHGAA
                     RGPRVGIWAGSASLDYLADHVLGQLDRSSPNRYLQQWVGVDKDYLAAQVAYRMDFGGPA
                     ITVQTACSTSLVAVALAVQGLLNYQCDVAVAGGVSIGLPQRQGYVHEDGSILAADGACR
                     PFTTQSSGTVFGNGAGAVVLRRLEDALDDGDTILAVIRGAAINNDGAAKVGFTAPGGRG
                     QGDVIRTALQLGEVDGASIGYVETHGTGTAIGDAVELSALMSALGDRQLDGQRCAIGSV
                     KANVGHMNAAAGVCGLIKVALAVQHAQIPPTVGAAHAIDALREGSPYYLPTDLTPWSSP
                     DRRAGVSSFGIGGTNAHVILEAS"
     aSModule        11682..16166
                     /domains="nrpspksdomains_spiB_PKS_KS.1"
                     /domains="nrpspksdomains_spiB_PKS_DHt.1"
                     /domains="nrpspksdomains_spiB_PKS_DH.1"
                     /domains="nrpspksdomains_spiB_PKS_KR.1"
                     /domains="nrpspksdomains_spiB_PKS_PP.1"
                     /incomplete
                     /locus_tags="spiB"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       12162..12209
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiB_0001"
                     /evalue="1.00E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="spiB"
                     /protein_end="185"
                     /protein_start="169"
                     /score="17.6"
                     /tool="antismash"
                     /translation="GPAITVQTACSTSLVA"
     CDS_motif       12585..12632
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiB_0002"
                     /evalue="8.10E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="spiB"
                     /protein_end="326"
                     /protein_start="310"
                     /score="11.8"
                     /tool="antismash"
                     /translation="YVETHGTGTAIGDAVE"
     CDS_motif       12693..12737
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiB_0003"
                     /evalue="1.90E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="spiB"
                     /protein_end="361"
                     /protein_start="346"
                     /score="10.9"
                     /tool="antismash"
                     /translation="GSVKANVGHMNAAAG"
     CDS_motif       13311..13400
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiB_0004"
                     /evalue="9.00E-05"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="spiB"
                     /protein_end="582"
                     /protein_start="552"
                     /score="15.3"
                     /tool="antismash"
                     /translation="GVVPSVVCGTGAGLFAAAFAAGALSAEDAR"
     aSDomain        13473..13853
                     /aSDomain="PKS_DHt"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiB_PKS_DHt.1"
                     /evalue="9.20E-07"
                     /label="spiB_PKS_DHt.1"
                     /locus_tag="spiB"
                     /protein_end="733"
                     /protein_start="606"
                     /score="20.8"
                     /tool="antismash"
                     /translation="SVEAVRKELAQVAQSGGDGASAVAATGATRVLEFGDNALGADVAG
                     VVSFAQGALDAIAGLWTSGIDLDLTKIYSGANRVSLPTYPFQRKRFWIDRAPRYTDSGT
                     SIFLGRRTEAPMLRASFFDAQWS"
     aSDomain        13794..14243
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiB_PKS_DH.1"
                     /evalue="4.30E-18"
                     /label="spiB_PKS_DH.1"
                     /locus_tag="spiB"
                     /protein_end="863"
                     /protein_start="713"
                     /score="58.1"
                     /tool="antismash"
                     /translation="LGRRTEAPMLRASFFDAQWSVATLPFLSDHMIYGKVIVSGAALAV
                     MIAEGVREVSKAHEFALHDLRFPAALVIPQGMGRRVQLQLVRDDDGFDATVLTQDPFEI
                     HATARVETTTTVSVVPSQEVQGIDTPTALLDSWLRDHGVVMGPSFS"
     CDS_motif       13869..13943
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiB_0005"
                     /evalue="1.50E-05"
                     /label="PKSI-DH_m2"
                     /locus_tag="spiB"
                     /protein_end="763"
                     /protein_start="738"
                     /score="17.6"
                     /tool="antismash"
                     /translation="FLSDHMIYGKVIVSGAALAVMIAEG"
     CDS_motif       15129..15224
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiB_0006"
                     /evalue="7.20E-10"
                     /label="PKSI-KR_m1"
                     /locus_tag="spiB"
                     /protein_end="1190"
                     /protein_start="1158"
                     /score="31.5"
                     /tool="antismash"
                     /translation="TWLITGGLGELGLRVASWLSALGVRSLVLTGR"
     aSDomain        15129..15662
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiB_PKS_KR.1"
                     /evalue="1.30E-56"
                     /label="spiB_PKS_KR.1"
                     /locus_tag="spiB"
                     /protein_end="1336"
                     /protein_start="1158"
                     /score="183.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="TWLITGGLGELGLRVASWLSALGVRSLVLTGRHSPDTNAQETLTV
                     FGHEGINVQVIQADLSSEADIEALLHKIDTTMPALRGICHLAGVVEDRLMGDVTPASLK
                     TTFAGKAEGAWLLHERTLHYPLKHFILFSSAAAAFGAPGQAAYAMANAYLDELAVYRRS
                     LGLPALSIAWGPWQD"
     CDS_motif       15504..15614
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiB_0007"
                     /evalue="4.10E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="spiB"
                     /protein_end="1320"
                     /protein_start="1283"
                     /score="61.2"
                     /tool="antismash"
                     /translation="LKHFILFSSAAAAFGAPGQAAYAMANAYLDELAVYRR"
     aSDomain        15927..16166
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiB_PKS_PP.1"
                     /evalue="1.30E-16"
                     /label="spiB_PKS_PP.1"
                     /locus_tag="spiB"
                     /protein_end="1504"
                     /protein_start="1424"
                     /score="52.6"
                     /tool="antismash"
                     /translation="LSPDERRHRLFQLIAEDVSSITGTDLATLDPERSLFEYDLDSLLI
                     TDLRLKFERRFGRPVAATVIFSNPTVAALADHMAQ"
     gene            16340..19867
                     /gene="spiC1"
     CDS             16340..19867
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (34-453). E-value:
                     6.2e-177. Score: 580.6. Matches aSDomain:
                     nrpspksdomains_spiC1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_DHt (495-685). E-value: 3.7e-09.
                     Score: 28.6. Matches aSDomain:
                     nrpspksdomains_spiC1_PKS_DHt.1"
                     /NRPS_PKS="Domain: PKS_KR (814-990). E-value: 4.9e-57.
                     Score: 184.6. Matches aSDomain:
                     nrpspksdomains_spiC1_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1074-1145). E-value: 4.1e-10.
                     Score: 31.8. Matches aSDomain:
                     nrpspksdomains_spiC1_PKS_PP.1"
                     /codon_start=1
                     /gene="spiC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 289.2; E-value:
                     9.5e-88)"
                     /gene_kind="biosynthetic-additional"
                     /product="polyketide synthase SpiC1"
                     /protein_id="AFR69333.1"
                     /sec_met_domain="hyb_KS (E-value: 2.7e-184, bitscore:
                     603.0, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 2.1e-50, bitscore:
                     161.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMSNPTTLMHDALIEIERLQRKLGGLEQQLKEPIAVAGMACRFA
                     GADSPEALWQLLLAGTDGVRAVPADRWDSERYFDADPDAAGHIYCRTGSFLEDIASFDA
                     GFFGISPREATMLDPQQRILLEVVWEAVERAGIPASALKGTATGVFVGVMHQDYAHRIR
                     NAADVDLYSASGNAASVLAGRISHVLGLHGPSITLDTACSSSLVAVHLACAALRAGECD
                     IAIVGGVNVVLSPISTAAECRAHMLSASGRCRPFDDSADGFVRGEGCGVVVLQRLSDAT
                     AAGRSIDALIAGSAVNHDGRSAGLTVPNEHAQRELIRTALRAANIDARQVQYVEAHGTG
                     TSLGDPIEAAALASVFASRAKDSPVLLGSIKSNLGHLEGAAGIAGLIKAILCVHHGVVP
                     ATLHVRQPNRGVDWNSVPLRLARQNEPMSGAQRVAGVSSFGFSGTNAHALVMAAPVSPA
                     VRGGGSFPQLLTVSAKSAASLLMNAVRFAEHLSRINEAELEDVCHSSRVARTHFPHRLA
                     VVASSAQEMANELRRFALGEQATVVSGLARAMSPRDAVGEAPYETLEAIAQGYVLGKPV
                     DLTRLAPERCRIAPLPTYAFDRQKYWLDERLGTAQAPALYRIAWRPILSVAPIPRSGQR
                     IIAGDDPQLCGEIAAALEAAGEQCTVVRAEAKAIQGAGNADLGVMLVFASIQTDAEPLE
                     AITRYGALIIELARALALNPSLGPVVMVTRGAAFTGPAEEIDPVAAAINAAVRVARREQ
                     GPLWGRSIDIDRSPQSLATLAALLGGAEDAEEDVVIRAAAILIPRLHRAGAGEGMPDIA
                     AEGVYVITGGTGALGLATARWLVRLGARNLLLISRHGEQEQNVRASCDQLRSEGVDVLV
                     ACADVADEASLRHALALVDRPIRGIVHCAGVIDDSTLVTMTPAAFAEVLRAKVGGGHLL
                     DRLTMNQPVDLFLLFSSISAALGRHGQAAYAAANAYLDALSQQRCLRGRPALSVGWGLW
                     AAGMGTTDPKVLERMRAGGLLALTETEAFGALEKAFSADAHLIIAAIDTPRMASQPNLP
                     RLLEDMVGGHPPMRRPVFDFEQLRGHNADARRALITEYLGRELQFILSSDVELPHDVSL
                     IELGMDSLTGSELRNAIERSTGIYVPMQHFIDGSPLNTAVEVIVGQLERRLVTTLPGRQ
                     GNSTEKMTL"
     aSDomain        16442..17698
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiC1_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="6.20E-177"
                     /label="spiC1_PKS_KS.1"
                     /locus_tag="spiC1"
                     /protein_end="453"
                     /protein_start="34"
                     /score="580.6"
                     /tool="antismash"
                     /translation="IAVAGMACRFAGADSPEALWQLLLAGTDGVRAVPADRWDSERYFD
                     ADPDAAGHIYCRTGSFLEDIASFDAGFFGISPREATMLDPQQRILLEVVWEAVERAGIP
                     ASALKGTATGVFVGVMHQDYAHRIRNAADVDLYSASGNAASVLAGRISHVLGLHGPSIT
                     LDTACSSSLVAVHLACAALRAGECDIAIVGGVNVVLSPISTAAECRAHMLSASGRCRPF
                     DDSADGFVRGEGCGVVVLQRLSDATAAGRSIDALIAGSAVNHDGRSAGLTVPNEHAQRE
                     LIRTALRAANIDARQVQYVEAHGTGTSLGDPIEAAALASVFASRAKDSPVLLGSIKSNL
                     GHLEGAAGIAGLIKAILCVHHGVVPATLHVRQPNRGVDWNSVPLRLARQNEPMSGAQRV
                     AGVSSFGFSGTNAHALVMAA"
     aSModule        16442..19774
                     /domains="nrpspksdomains_spiC1_PKS_KS.1"
                     /domains="nrpspksdomains_spiC1_PKS_DHt.1"
                     /domains="nrpspksdomains_spiC1_PKS_KR.1"
                     /domains="nrpspksdomains_spiC1_PKS_PP.1"
                     /incomplete
                     /locus_tags="spiC1"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       16916..16963
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC1_0001"
                     /evalue="9.90E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="spiC1"
                     /protein_end="208"
                     /protein_start="192"
                     /score="20.6"
                     /tool="antismash"
                     /translation="GPSITLDTACSSSLVA"
     CDS_motif       17105..17143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC1_0002"
                     /evalue="2.10E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="spiC1"
                     /protein_end="268"
                     /protein_start="255"
                     /score="14.3"
                     /tool="antismash"
                     /translation="FDDSADGFVRGEG"
     CDS_motif       17336..17383
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC1_0003"
                     /evalue="6.80E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="spiC1"
                     /protein_end="348"
                     /protein_start="332"
                     /score="14.6"
                     /tool="antismash"
                     /translation="YVEAHGTGTSLGDPIE"
     CDS_motif       17441..17485
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC1_0004"
                     /evalue="1.20E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="spiC1"
                     /protein_end="382"
                     /protein_start="367"
                     /score="11.4"
                     /tool="antismash"
                     /translation="GSIKSNLGHLEGAAG"
     aSDomain        17825..18394
                     /aSDomain="PKS_DHt"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiC1_PKS_DHt.1"
                     /evalue="3.70E-09"
                     /label="spiC1_PKS_DHt.1"
                     /locus_tag="spiC1"
                     /protein_end="685"
                     /protein_start="495"
                     /score="28.6"
                     /tool="antismash"
                     /translation="AELEDVCHSSRVARTHFPHRLAVVASSAQEMANELRRFALGEQAT
                     VVSGLARAMSPRDAVGEAPYETLEAIAQGYVLGKPVDLTRLAPERCRIAPLPTYAFDRQ
                     KYWLDERLGTAQAPALYRIAWRPILSVAPIPRSGQRIIAGDDPQLCGEIAAALEAAGEQ
                     CTVVRAEAKAIQGAGNADLGVMLVFAS"
     CDS_motif       18038..18058
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC1_0005"
                     /evalue="4.50E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="spiC1"
                     /protein_end="573"
                     /protein_start="566"
                     /score="-1.3"
                     /tool="antismash"
                     /translation="AQGYVLG"
     aSDomain        18782..19309
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiC1_PKS_KR.1"
                     /evalue="4.90E-57"
                     /label="spiC1_PKS_KR.1"
                     /locus_tag="spiC1"
                     /protein_end="990"
                     /protein_start="814"
                     /score="184.6"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GVYVITGGTGALGLATARWLVRLGARNLLLISRHGEQEQNVRASC
                     DQLRSEGVDVLVACADVADEASLRHALALVDRPIRGIVHCAGVIDDSTLVTMTPAAFAE
                     VLRAKVGGGHLLDRLTMNQPVDLFLLFSSISAALGRHGQAAYAAANAYLDALSQQRCLR
                     GRPALSVGWGLWA"
     CDS_motif       18785..18880
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC1_0006"
                     /evalue="2.60E-14"
                     /label="PKSI-KR_m1"
                     /locus_tag="spiC1"
                     /protein_end="847"
                     /protein_start="815"
                     /score="45.7"
                     /tool="antismash"
                     /translation="VYVITGGTGALGLATARWLVRLGARNLLLISR"
     CDS_motif       19154..19261
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC1_0007"
                     /evalue="6.20E-17"
                     /label="PKSI-KR_m4"
                     /locus_tag="spiC1"
                     /protein_end="974"
                     /protein_start="938"
                     /score="54.1"
                     /tool="antismash"
                     /translation="VDLFLLFSSISAALGRHGQAAYAAANAYLDALSQQR"
     aSDomain        19562..19774
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiC1_PKS_PP.1"
                     /evalue="4.10E-10"
                     /label="spiC1_PKS_PP.1"
                     /locus_tag="spiC1"
                     /protein_end="1145"
                     /protein_start="1074"
                     /score="31.8"
                     /tool="antismash"
                     /translation="NADARRALITEYLGRELQFILSSDVELPHDVSLIELGMDSLTGSE
                     LRNAIERSTGIYVPMQHFIDGSPLNT"
     gene            19864..32109
                     /gene="spiDE1"
     CDS             19864..32109
                     /NRPS_PKS="Domain: Condensation_LCL (71-357). E-value:
                     1.2e-60. Score: 196.9. Matches aSDomain:
                     nrpspksdomains_spiDE1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (525-919). E-value:
                     2.9e-104. Score: 340.7. Matches aSDomain:
                     nrpspksdomains_spiDE1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1024-1086). E-value: 7.6e-23.
                     Score: 72.4. Matches aSDomain: nrpspksdomains_spiDE1_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1104-1401). E-value:
                     3.1e-81. Score: 265.0. Matches aSDomain:
                     nrpspksdomains_spiDE1_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1404-1554). E-value: 3.8e-34.
                     Score: 109.6. Matches aSDomain:
                     nrpspksdomains_spiDE1_TIGR01720.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1562-1859). E-value:
                     1.8e-89. Score: 291.6. Matches aSDomain:
                     nrpspksdomains_spiDE1_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (2021-2412). E-value:
                     1.6e-85. Score: 279.0. Matches aSDomain:
                     nrpspksdomains_spiDE1_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2516-2578). E-value: 1.2e-22.
                     Score: 71.8. Matches aSDomain: nrpspksdomains_spiDE1_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (2596-2893). E-value:
                     3.1e-81. Score: 265.0. Matches aSDomain:
                     nrpspksdomains_spiDE1_Epimerization.2"
                     /NRPS_PKS="Domain: TIGR01720 (2896-3025). E-value: 1.6e-25.
                     Score: 81.6. Matches aSDomain:
                     nrpspksdomains_spiDE1_TIGR01720.2"
                     /NRPS_PKS="Domain: Condensation_DCL (3037-3326). E-value:
                     6.6e-77. Score: 250.4. Matches aSDomain:
                     nrpspksdomains_spiDE1_Condensation_DCL.2"
                     /NRPS_PKS="Domain: AMP-binding (3489-3876). E-value: 1e-99.
                     Score: 325.8. Matches aSDomain:
                     nrpspksdomains_spiDE1_AMP-binding.3"
                     /NRPS_PKS="Domain: PCP (3980-4049). E-value: 1.4e-14.
                     Score: 45.9. Matches aSDomain: nrpspksdomains_spiDE1_PCP.3"
                     /codon_start=1
                     /gene="spiDE1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     275.9; E-value: 1.2e-83)"
                     /gene_kind="biosynthetic"
                     /product="nonribosomal peptide synthetase SpiDE1"
                     /protein_id="AFR69334.1"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-110, bitscore:
                     359.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.3e-15, bitscore:
                     45.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 5.8e-63, bitscore:
                     202.7, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIAQLLADLADVGVTLRRCGEQLEVEGPTGSLGPDLLERLRQSK
                     QALLQMIQDENALLTKMPLPVPGEGTEACELSLGQQRLVVATQLGEPTIYNEQAAIEFA
                     ADVDVLAITEAFAALAHKHDILHTVFTDDEPSQQTVIADARVPLQSWEVRSNDELHTLA
                     RSIAQIPFVNGKLLWRVDLFYKATGSVVLVLTIHHAIFDRWTMMLLIRDFSQFLQHPSH
                     VNVAQAASLTYRDFSVWQRRWMDTPEYAAQLDWWKDLLSGIDSFPVIQGDRPPPAVPSG
                     RGATERMKIPADCIRAASEFSRQQNTTLFSTLLSIFQLLHHRYTGESQVLTLAPVASRP
                     FQEAEEIAGFFVNLVAIVGRVYKDDTFHSLVERTRGITTQAFSHQFVPFDAVVEHLRQT
                     RGPRSDQLAHVVFALQNVNLPTVRVEGVDAKPFDLDSPFARFDLYLSIEGDERGMFAVW
                     QYSQDLFDASTIRKMGEHYVSLLRGVLAAPEAPLQSLPMYSDVEYAQLQAWSRHEQPYR
                     ADATVVALFREQAAAHPEQTALEQGTECWTYAQLERWSDRAAAVLRSAGAGRGSIIGVT
                     GERSPRLIAAFLACLKAGGAYLPLERNYPDARLSEMVADAEPALILVADDLEPGWLSSY
                     PGPVLKLSACEAELPFPSTLESGAGDLAYVMYTSGSTGKPKGVCIEHRGIVRLATGAGF
                     MQLDTSTVMLQASSLGFDTSTFEIWGCLLNGGRLVLVEQGPLILEAMADTIVSKGVTCA
                     WLTADLFRLMVEEQVASLRGLRELLAGGDALPVASCKAFLEACPDVALINGYGPTENTT
                     FTSTHRVTQEDVHRVSIPIGRPLGNTQVWVVNENGCPVPPGVPGELWTSGDGLARGYLG
                     REDLTVERFVQGPLLGGGRWYRTGDRVRWRHDGVLEFLGRIDTQVKLRGYRIELGEIEM
                     VLGAHPSVSGCAMALKENAAGDKQLVGYVVARSGAAVSTAQVQAWLGERLPGYMVPSIW
                     VWLQTLPQSPSGKVDRKHLPLPAFEIGSVKASTAAEAALVNIWQSLLGLAQVGVQDNFF
                     ALGGDSILAIQMASRAAEQDVRITAQDVFRYPTIAQLAVNGGFGAAQGVLAEQGLVDGE
                     VALSPIQKWYVDWPGADWEQFSQGVYFDLHAQVDPQLLSASLAAVARHHDVLGIGWRHD
                     GSTWHQESGAGAAVEVLVEDLRGQADALACLEQSAGALQQSLSLNAASVWAARIYRLDE
                     GWRLVWLVHHVSVDGVSWRILLEDLLRAYGALQRGEAVSLPAKTVSYQAWTQHLATWGN
                     QLPASQLAYWQRMEGSGTDVPMDGDASVSEVGSEARVSLQLDRLMTQQLLREAGERYRV
                     RPEELLVAALARTLCAWSASQECVVDIEGHGRDGVEGVDVGRTVGWFTSLYPLRLTLEG
                     GLANDLKAVKERMRGVPHGGQSYGALRYGREDSGLGRHERSVSFNYLGQWRLDELGTPL
                     AGWRGQAPGGSRRPTMRRRHALEVLAYVQESQLHVDFQYSDLLHRAETMATLAHSFQVE
                     LQALLTHCLSVERGGLTPSDLPLAHLDQNEIDEIEHDHPQLADMYGVTPLQQGILFHSV
                     AQNPSFLYVEQLHWRIVGEFRADCFQQAWSEVIRAHAALRTTFRWRDLKTPVQLVHHLL
                     EPDWGTLDWRELSAETCRTRFENLLNTDRERGFDLEHGPLLRGTLIREQESSWRFLWTY
                     HHVVFDGWSVALILKQVLNRYAGLNAGAEILPSSLRPFVSWLSGRDQEDMSVYWQEVLG
                     GIVEPTLTGFESPAHNRQALARDRCAFRVDDALCDALGLAARQAGITQASVLTGAWALT
                     LGLAGGGSDVLFGTTLSGRPADLQQVELTVGLFINTVPVRVRIDDDDVVSDWLQRLHRQ
                     QSEREKYSTASLTTVQRWAGLNGGDLLSSLFVVENYPIDSMLKQSDIGVDITELTSIGH
                     TNFPLTAQWVPGEETVLHVIFDTSRYDEVSIRRLGDSFLRVLRQLVLQPQSRIGEISLV
                     SEAQTQQLIYDWNDTPATSDGFLLHEGIKRYAALTPKAAAVIGVSDRMSYDELAAQQER
                     IATSVVAANARSEPVAVFLPRSLHAVAAYAGVMLAGCAYVPVDPATPPRRLQEIFSTIG
                     FVVTTRALAPQFDAIAVQTILVDEVVSAQLPDVAINNLAYVMFTSGSTGKPKGVMIDHR
                     AASLTIESIIERYAIGTRDRLLCVSSAGFDLSVFDFFGAFAVGAAVVLAPESTTVDPGT
                     WLDLMEREQVTVWESVPAVMELLLAECRQSGRKLSSSLRLVMLSGDRVALGLPERIREA
                     ATSELDIIALGGATEAAIWSCYYDTKELAPGAHVIPYGRHLPGQRLYVLSPALRPLPIG
                     VPGDLWIAGAGVARGYLGQPELTSERFMADPYVPGQSMYKTGDRALVLADGNHEFLGRV
                     DDQIKIGGLRIELGEIEAALMQAPGVERGVVSIVEHDGRRMIAAYVLPHAAEAFDTVAV
                     GESLRQALPAYMLPASIMTLESVPLTANGKVDRKRLPLPAFEIGSVKASTAAEAVLVNI
                     WQSLLGLAQVGVQDNFFALGGDSILAIQMASRAAEQDVRITAQDVFRYPTIAQLAVNGG
                     FGAAQGVLAEQGLVDGEVALSPIQKWYVDWPGADWEQFSQGVYFDLHAQVDPQLLSASL
                     AAVARHHDVLGIGWRHDGSTWHQESGAGAAVEVLVEDLRGQADALACLEQSAGALQQSL
                     SLNAASVWAARIYRLDEGWRLVWLVHHVSVDGVSWRILLEDLLRAYGALQRGEAVSLPA
                     KTVSYQAWTQHLATWGNQLPASQLAYWQRMEGSGTDVPMDGDASVSEVGSEARVSLQLD
                     RLMTQQLLREAGERYRVRPEELLVAALARTLCAWSASQECVVDIEGHGRDGVEGVDVGR
                     TVGWFTSLYPLRLTLEGGLANDLKAVKERMRGVPHGGQSYGALRYGREDSGLGRHERSV
                     SFNYLGQWRLDELGTPLAGWRGQAPGGSRRPTMRRRHALEVLAYVQESQLHVDFQYSDL
                     LHRAETMATLAHSFQVELQALLTHCLSVNEGVTALVAQLNNVEAVYGLTPMQEGMLYHA
                     LARDGMYVEQLACTLTGILDEQALQDAWNDVVASNPVLRTSFHWEGLARPVQVVHQVAQ
                     VPWVLESWAEGLDMDAWLRADRRKGLDLRTAPCLRCALLHTGPQRYEWVVTYSHLLLDG
                     WSLSLMIEALAQAYAAQTAGQPYQPPVRSPFIDYVSWSQATLDQGVGEHFWHSQLYGFE
                     GVRSLSLPVPDVTEAYAEPVLINVQRSLVATLEKQQRVTLATVVAGCWAVLLSRYGEGD
                     DVLFGMTSAGRRAQIEGSESMMGLLIETRPTRIEVDEQAPLGDWLRTIMQEEAKREEAG
                     AVSLAQIESWGGAERGARLFDTLVVVENQPMAMIGDLLGSQVVVANVRTVECTNWPLTV
                     VVLPEQEQLRLVFLYDPEHYARQAIEQVARHFSTLLASAGEAVQVADLQMLDEAEREML
                     VERWSGADQVHAASNRTIVERIEEQATLRPDAIALRLGERSMSYAELTTRGRRVAAWLQ
                     RQDVGVGGRVAIVGERTMETIAAMYGILLSGAAYVPLDPDWPEERKRLVIEDAQPQVFI
                     GSTHMACGSSLQISLETLEGFTDERLTGRSATPQDLAYVIFTSGSTGRPKGVMVRHADV
                     MHLDGLQDAMALSDADVWTSFHSYAFDFSVLEIWYPLMWGATVVPVPYWVSREPEAFLA
                     LICAEKVTIICQTPAAFEQLISTARPGCRAGHVRWVLLGGDRYSAALFAAGDPAEFPNI
                     ANVYGITETTVITTFEPLERDRPVAIGRPFPGQRIYLLDRKKRLVPPGAVGEMYICGEG
                     VAAGYMGAEALTAQRFSDDPYQPGARMYRSGDLARFLPGGRLESIGRADHQVKIRGYRI
                     ELGEVESALSSLAVVNGAIVDVRNGPNGRQLVAWYVAAESVSALDVRAALKSLLPESAI
                     PSALIRVDAFPLTPNGKVDRKALPLEDAVSLPSIRPSSHNEMAIEAIWCEVLGQEAIGV
                     HTNFFDAGGDSIAIVRVHGLMAVLPGAERLRVVDLFQCPTIAAIAEKITSSEAQTAVGD
                     DSSARGVRRRQALERHQNARSKPQ"
     aSDomain        20077..20934
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiDE1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.20E-60"
                     /label="spiDE1_Condensation_LCL.1"
                     /locus_tag="spiDE1"
                     /protein_end="357"
                     /protein_start="71"
                     /score="196.9"
                     /tool="antismash"
                     /translation="EACELSLGQQRLVVATQLGEPTIYNEQAAIEFAADVDVLAITEAF
                     AALAHKHDILHTVFTDDEPSQQTVIADARVPLQSWEVRSNDELHTLARSIAQIPFVNGK
                     LLWRVDLFYKATGSVVLVLTIHHAIFDRWTMMLLIRDFSQFLQHPSHVNVAQAASLTYR
                     DFSVWQRRWMDTPEYAAQLDWWKDLLSGIDSFPVIQGDRPPPAVPSGRGATERMKIPAD
                     CIRAASEFSRQQNTTLFSTLLSIFQLLHHRYTGESQVLTLAPVASRPFQEAEEIAGFFV
                     NLVAI"
     aSModule        20077..24525
                     /complete
                     /domains="nrpspksdomains_spiDE1_Condensation_LCL.1"
                     /domains="nrpspksdomains_spiDE1_AMP-binding.1"
                     /domains="nrpspksdomains_spiDE1_PCP.1"
                     /domains="nrpspksdomains_spiDE1_Epimerization.1"
                     /domains="nrpspksdomains_spiDE1_TIGR01720.1"
                     /locus_tags="spiDE1"
                     /monomer_pairings="Ala -> D-Ala"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20140..20253
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0001"
                     /evalue="3.80E-09"
                     /label="C2_LCL_024-062"
                     /locus_tag="spiDE1"
                     /protein_end="130"
                     /protein_start="92"
                     /score="28.9"
                     /tool="antismash"
                     /translation="TIYNEQAAIEFAADVDVLAITEAFAALAHKHDILHTVF"
     CDS_motif       20449..20511
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0002"
                     /evalue="1.00E-05"
                     /label="C3_LCL_132-143"
                     /locus_tag="spiDE1"
                     /protein_end="216"
                     /protein_start="195"
                     /score="18.2"
                     /tool="antismash"
                     /translation="IHHAIFDRWTMMLLIRDFSQF"
     CDS_motif       20863..20934
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0003"
                     /evalue="3.60E-05"
                     /label="C5_LCL_267-296"
                     /locus_tag="spiDE1"
                     /protein_end="357"
                     /protein_start="333"
                     /score="16.3"
                     /tool="antismash"
                     /translation="APVASRPFQEAEEIAGFFVNLVAI"
     CDS_motif       20995..21105
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0004"
                     /evalue="1.20E-07"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="spiDE1"
                     /protein_end="414"
                     /protein_start="377"
                     /score="24.0"
                     /tool="antismash"
                     /translation="TTQAFSHQFVPFDAVVEHLRQTRGPRSDQLAHVVFAL"
     aSDomain        21439..22620
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiDE1_AMP-binding.1"
                     /evalue="2.90E-104"
                     /label="spiDE1_AMP-binding.1"
                     /locus_tag="spiDE1"
                     /protein_end="919"
                     /protein_start="525"
                     /score="340.7"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="FREQAAAHPEQTALEQGTECWTYAQLERWSDRAAAVLRSAGAGRG
                     SIIGVTGERSPRLIAAFLACLKAGGAYLPLERNYPDARLSEMVADAEPALILVADDLEP
                     GWLSSYPGPVLKLSACEAELPFPSTLESGAGDLAYVMYTSGSTGKPKGVCIEHRGIVRL
                     ATGAGFMQLDTSTVMLQASSLGFDTSTFEIWGCLLNGGRLVLVEQGPLILEAMADTIVS
                     KGVTCAWLTADLFRLMVEEQVASLRGLRELLAGGDALPVASCKAFLEACPDVALINGYG
                     PTENTTFTSTHRVTQEDVHRVSIPIGRPLGNTQVWVVNENGCPVPPGVPGELWTSGDGL
                     ARGYLGREDLTVERFVQGPLLGGGRWYRTGDRVRWRHDGVLEFLGRIDTQVKLR"
     CDS_motif       21625..21663
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0005"
                     /evalue="9.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="spiDE1"
                     /protein_end="600"
                     /protein_start="587"
                     /score="15.7"
                     /tool="antismash"
                     /translation="LACLKAGGAYLPL"
     CDS_motif       21850..21909
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0006"
                     /evalue="3.70E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="spiDE1"
                     /protein_end="682"
                     /protein_start="662"
                     /score="31.6"
                     /tool="antismash"
                     /translation="AYVMYTSGSTGKPKGVCIEH"
     CDS_motif       22414..22503
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0007"
                     /evalue="7.60E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="spiDE1"
                     /protein_end="880"
                     /protein_start="850"
                     /score="47.0"
                     /tool="antismash"
                     /translation="PPGVPGELWTSGDGLARGYLGREDLTVERF"
     CDS_motif       22585..22650
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0008"
                     /evalue="1.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="spiDE1"
                     /protein_end="929"
                     /protein_start="907"
                     /score="36.6"
                     /tool="antismash"
                     /translation="FLGRIDTQVKLRGYRIELGEIE"
     CDS_motif       22864..22890
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0009"
                     /evalue="1.90E+00"
                     /label="NRPS-A_a10"
                     /locus_tag="spiDE1"
                     /protein_end="1009"
                     /protein_start="1000"
                     /score="2.3"
                     /tool="antismash"
                     /translation="GKVDRKHLP"
     aSDomain        22936..23121
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiDE1_PCP.1"
                     /evalue="7.60E-23"
                     /label="spiDE1_PCP.1"
                     /locus_tag="spiDE1"
                     /protein_end="1086"
                     /protein_start="1024"
                     /score="72.4"
                     /tool="antismash"
                     /translation="EAALVNIWQSLLGLAQVGVQDNFFALGGDSILAIQMASRAAEQDV
                     RITAQDVFRYPTIAQLA"
     CDS_motif       22999..23028
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0010"
                     /evalue="3.60E-01"
                     /label="PCP_mE"
                     /locus_tag="spiDE1"
                     /protein_end="1055"
                     /protein_start="1045"
                     /score="4.5"
                     /tool="antismash"
                     /translation="NFFALGGDSI"
     aSDomain        23176..24066
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiDE1_Epimerization.1"
                     /evalue="3.10E-81"
                     /label="spiDE1_Epimerization.1"
                     /locus_tag="spiDE1"
                     /protein_end="1401"
                     /protein_start="1104"
                     /score="265.0"
                     /tool="antismash"
                     /translation="DGEVALSPIQKWYVDWPGADWEQFSQGVYFDLHAQVDPQLLSASL
                     AAVARHHDVLGIGWRHDGSTWHQESGAGAAVEVLVEDLRGQADALACLEQSAGALQQSL
                     SLNAASVWAARIYRLDEGWRLVWLVHHVSVDGVSWRILLEDLLRAYGALQRGEAVSLPA
                     KTVSYQAWTQHLATWGNQLPASQLAYWQRMEGSGTDVPMDGDASVSEVGSEARVSLQLD
                     RLMTQQLLREAGERYRVRPEELLVAALARTLCAWSASQECVVDIEGHGRDGVEGVDVGR
                     TVGWFTSLYPLRLTLE"
     CDS_motif       23191..23217
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0011"
                     /evalue="2.00E-01"
                     /label="NRPS-E1"
                     /locus_tag="spiDE1"
                     /protein_end="1118"
                     /protein_start="1109"
                     /score="5.4"
                     /tool="antismash"
                     /translation="LSPIQKWYV"
     CDS_motif       23257..23340
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0012"
                     /evalue="4.70E-04"
                     /label="C2_DCL_024-062"
                     /locus_tag="spiDE1"
                     /protein_end="1159"
                     /protein_start="1131"
                     /score="12.5"
                     /tool="antismash"
                     /translation="VYFDLHAQVDPQLLSASLAAVARHHDVL"
     CDS_motif       23548..23613
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0013"
                     /evalue="3.60E-08"
                     /label="NRPS-E2"
                     /locus_tag="spiDE1"
                     /protein_end="1250"
                     /protein_start="1228"
                     /score="25.8"
                     /tool="antismash"
                     /translation="LVWLVHHVSVDGVSWRILLEDL"
     CDS_motif       24007..24057
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0014"
                     /evalue="1.50E-07"
                     /label="NRPS-E5"
                     /locus_tag="spiDE1"
                     /protein_end="1398"
                     /protein_start="1381"
                     /score="23.6"
                     /tool="antismash"
                     /translation="DVGRTVGWFTSLYPLRL"
     aSDomain        24076..24525
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiDE1_TIGR01720.1"
                     /evalue="3.80E-34"
                     /label="spiDE1_TIGR01720.1"
                     /locus_tag="spiDE1"
                     /protein_end="1554"
                     /protein_start="1404"
                     /score="109.6"
                     /tool="antismash"
                     /translation="ANDLKAVKERMRGVPHGGQSYGALRYGREDSGLGRHERSVSFNYL
                     GQWRLDELGTPLAGWRGQAPGGSRRPTMRRRHALEVLAYVQESQLHVDFQYSDLLHRAE
                     TMATLAHSFQVELQALLTHCLSVERGGLTPSDLPLAHLDQNEIDEI"
     CDS_motif       24094..24153
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0015"
                     /evalue="1.30E-06"
                     /label="NRPS-E6"
                     /locus_tag="spiDE1"
                     /protein_end="1430"
                     /protein_start="1410"
                     /score="20.8"
                     /tool="antismash"
                     /translation="VKERMRGVPHGGQSYGALRY"
     CDS_motif       24193..24216
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0016"
                     /evalue="2.00E-01"
                     /label="NRPS-E7"
                     /locus_tag="spiDE1"
                     /protein_end="1451"
                     /protein_start="1443"
                     /score="5.0"
                     /tool="antismash"
                     /translation="VSFNYLGQ"
     aSDomain        24550..25440
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiDE1_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.80E-89"
                     /label="spiDE1_Condensation_DCL.1"
                     /locus_tag="spiDE1"
                     /protein_end="1859"
                     /protein_start="1562"
                     /score="291.6"
                     /tool="antismash"
                     /translation="DMYGVTPLQQGILFHSVAQNPSFLYVEQLHWRIVGEFRADCFQQA
                     WSEVIRAHAALRTTFRWRDLKTPVQLVHHLLEPDWGTLDWRELSAETCRTRFENLLNTD
                     RERGFDLEHGPLLRGTLIREQESSWRFLWTYHHVVFDGWSVALILKQVLNRYAGLNAGA
                     EILPSSLRPFVSWLSGRDQEDMSVYWQEVLGGIVEPTLTGFESPAHNRQALARDRCAFR
                     VDDALCDALGLAARQAGITQASVLTGAWALTLGLAGGGSDVLFGTTLSGRPADLQQVEL
                     TVGLFINTVPVRVRID"
     aSModule        24550..28938
                     /complete
                     /domains="nrpspksdomains_spiDE1_Condensation_DCL.1"
                     /domains="nrpspksdomains_spiDE1_AMP-binding.2"
                     /domains="nrpspksdomains_spiDE1_PCP.2"
                     /domains="nrpspksdomains_spiDE1_Epimerization.2"
                     /domains="nrpspksdomains_spiDE1_TIGR01720.2"
                     /locus_tags="spiDE1"
                     /monomer_pairings="Cys -> D-Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       24556..24594
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0017"
                     /evalue="4.80E-03"
                     /label="C1_dual_004-017"
                     /locus_tag="spiDE1"
                     /protein_end="1577"
                     /protein_start="1564"
                     /score="10.1"
                     /tool="antismash"
                     /translation="YGVTPLQQGILFH"
     CDS_motif       24619..24735
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0018"
                     /evalue="2.70E-13"
                     /label="C2_DCL_024-062"
                     /locus_tag="spiDE1"
                     /protein_end="1624"
                     /protein_start="1585"
                     /score="42.2"
                     /tool="antismash"
                     /translation="LYVEQLHWRIVGEFRADCFQQAWSEVIRAHAALRTTFRW"
     CDS_motif       24952..25017
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0019"
                     /evalue="2.80E-07"
                     /label="C3_DCL_135-156"
                     /locus_tag="spiDE1"
                     /protein_end="1718"
                     /protein_start="1696"
                     /score="23.1"
                     /tool="antismash"
                     /translation="YHHVVFDGWSVALILKQVLNRY"
     CDS_motif       25333..25428
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0020"
                     /evalue="5.20E-17"
                     /label="C5_DCL_263-294"
                     /locus_tag="spiDE1"
                     /protein_end="1855"
                     /protein_start="1823"
                     /score="54.2"
                     /tool="antismash"
                     /translation="DVLFGTTLSGRPADLQQVELTVGLFINTVPVR"
     CDS_motif       25477..25596
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0021"
                     /evalue="9.60E-13"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="spiDE1"
                     /protein_end="1911"
                     /protein_start="1871"
                     /score="40.5"
                     /tool="antismash"
                     /translation="HRQQSEREKYSTASLTTVQRWAGLNGGDLLSSLFVVENYP"
     aSDomain        25927..27099
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiDE1_AMP-binding.2"
                     /evalue="1.60E-85"
                     /label="spiDE1_AMP-binding.2"
                     /locus_tag="spiDE1"
                     /protein_end="2412"
                     /protein_start="2021"
                     /score="279.0"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="RYAALTPKAAAVIGVSDRMSYDELAAQQERIATSVVAANARSEPV
                     AVFLPRSLHAVAAYAGVMLAGCAYVPVDPATPPRRLQEIFSTIGFVVTTRALAPQFDAI
                     AVQTILVDEVVSAQLPDVAINNLAYVMFTSGSTGKPKGVMIDHRAASLTIESIIERYAI
                     GTRDRLLCVSSAGFDLSVFDFFGAFAVGAAVVLAPESTTVDPGTWLDLMEREQVTVWES
                     VPAVMELLLAECRQSGRKLSSSLRLVMLSGDRVALGLPERIREAATSELDIIALGGATE
                     AAIWSCYYDTKELAPGAHVIPYGRHLPGQRLYVLSPALRPLPIGVPGDLWIAGAGVARG
                     YLGQPELTSERFMADPYVPGQSMYKTGDRALVLADGNHEFLGRVDDQIKIG"
     CDS_motif       26107..26145
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0022"
                     /evalue="3.90E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="spiDE1"
                     /protein_end="2094"
                     /protein_start="2081"
                     /score="10.9"
                     /tool="antismash"
                     /translation="GVMLAGCAYVPVD"
     CDS_motif       26308..26367
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0023"
                     /evalue="2.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="spiDE1"
                     /protein_end="2168"
                     /protein_start="2148"
                     /score="32.3"
                     /tool="antismash"
                     /translation="AYVMFTSGSTGKPKGVMIDH"
     CDS_motif       26893..26982
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0024"
                     /evalue="2.80E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="spiDE1"
                     /protein_end="2373"
                     /protein_start="2343"
                     /score="51.6"
                     /tool="antismash"
                     /translation="PIGVPGDLWIAGAGVARGYLGQPELTSERF"
     CDS_motif       27064..27129
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0025"
                     /evalue="6.80E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="spiDE1"
                     /protein_end="2422"
                     /protein_start="2400"
                     /score="31.1"
                     /tool="antismash"
                     /translation="FLGRVDDQIKIGGLRIELGEIE"
     CDS_motif       27340..27366
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0026"
                     /evalue="8.40E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="spiDE1"
                     /protein_end="2501"
                     /protein_start="2492"
                     /score="3.2"
                     /tool="antismash"
                     /translation="GKVDRKRLP"
     aSDomain        27412..27597
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiDE1_PCP.2"
                     /evalue="1.20E-22"
                     /label="spiDE1_PCP.2"
                     /locus_tag="spiDE1"
                     /protein_end="2578"
                     /protein_start="2516"
                     /score="71.8"
                     /tool="antismash"
                     /translation="EAVLVNIWQSLLGLAQVGVQDNFFALGGDSILAIQMASRAAEQDV
                     RITAQDVFRYPTIAQLA"
     CDS_motif       27475..27504
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0027"
                     /evalue="3.60E-01"
                     /label="PCP_mE"
                     /locus_tag="spiDE1"
                     /protein_end="2547"
                     /protein_start="2537"
                     /score="4.5"
                     /tool="antismash"
                     /translation="NFFALGGDSI"
     aSDomain        27652..28542
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiDE1_Epimerization.2"
                     /evalue="3.10E-81"
                     /label="spiDE1_Epimerization.2"
                     /locus_tag="spiDE1"
                     /protein_end="2893"
                     /protein_start="2596"
                     /score="265.0"
                     /tool="antismash"
                     /translation="DGEVALSPIQKWYVDWPGADWEQFSQGVYFDLHAQVDPQLLSASL
                     AAVARHHDVLGIGWRHDGSTWHQESGAGAAVEVLVEDLRGQADALACLEQSAGALQQSL
                     SLNAASVWAARIYRLDEGWRLVWLVHHVSVDGVSWRILLEDLLRAYGALQRGEAVSLPA
                     KTVSYQAWTQHLATWGNQLPASQLAYWQRMEGSGTDVPMDGDASVSEVGSEARVSLQLD
                     RLMTQQLLREAGERYRVRPEELLVAALARTLCAWSASQECVVDIEGHGRDGVEGVDVGR
                     TVGWFTSLYPLRLTLE"
     CDS_motif       27667..27693
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0028"
                     /evalue="2.00E-01"
                     /label="NRPS-E1"
                     /locus_tag="spiDE1"
                     /protein_end="2610"
                     /protein_start="2601"
                     /score="5.4"
                     /tool="antismash"
                     /translation="LSPIQKWYV"
     CDS_motif       27733..27816
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0029"
                     /evalue="4.70E-04"
                     /label="C2_DCL_024-062"
                     /locus_tag="spiDE1"
                     /protein_end="2651"
                     /protein_start="2623"
                     /score="12.5"
                     /tool="antismash"
                     /translation="VYFDLHAQVDPQLLSASLAAVARHHDVL"
     CDS_motif       28024..28089
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0030"
                     /evalue="3.60E-08"
                     /label="NRPS-E2"
                     /locus_tag="spiDE1"
                     /protein_end="2742"
                     /protein_start="2720"
                     /score="25.8"
                     /tool="antismash"
                     /translation="LVWLVHHVSVDGVSWRILLEDL"
     CDS_motif       28483..28533
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0031"
                     /evalue="1.50E-07"
                     /label="NRPS-E5"
                     /locus_tag="spiDE1"
                     /protein_end="2890"
                     /protein_start="2873"
                     /score="23.6"
                     /tool="antismash"
                     /translation="DVGRTVGWFTSLYPLRL"
     aSDomain        28552..28938
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiDE1_TIGR01720.2"
                     /evalue="1.60E-25"
                     /label="spiDE1_TIGR01720.2"
                     /locus_tag="spiDE1"
                     /protein_end="3025"
                     /protein_start="2896"
                     /score="81.6"
                     /tool="antismash"
                     /translation="ANDLKAVKERMRGVPHGGQSYGALRYGREDSGLGRHERSVSFNYL
                     GQWRLDELGTPLAGWRGQAPGGSRRPTMRRRHALEVLAYVQESQLHVDFQYSDLLHRAE
                     TMATLAHSFQVELQALLTHCLSVNE"
     CDS_motif       28570..28629
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0032"
                     /evalue="1.30E-06"
                     /label="NRPS-E6"
                     /locus_tag="spiDE1"
                     /protein_end="2922"
                     /protein_start="2902"
                     /score="20.8"
                     /tool="antismash"
                     /translation="VKERMRGVPHGGQSYGALRY"
     CDS_motif       28669..28692
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0033"
                     /evalue="2.00E-01"
                     /label="NRPS-E7"
                     /locus_tag="spiDE1"
                     /protein_end="2943"
                     /protein_start="2935"
                     /score="5.0"
                     /tool="antismash"
                     /translation="VSFNYLGQ"
     aSDomain        28975..29841
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiDE1_Condensation_DCL.2"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="6.60E-77"
                     /label="spiDE1_Condensation_DCL.2"
                     /locus_tag="spiDE1"
                     /protein_end="3326"
                     /protein_start="3037"
                     /score="250.4"
                     /tool="antismash"
                     /translation="EAVYGLTPMQEGMLYHALARDGMYVEQLACTLTGILDEQALQDAW
                     NDVVASNPVLRTSFHWEGLARPVQVVHQVAQVPWVLESWAEGLDMDAWLRADRRKGLDL
                     RTAPCLRCALLHTGPQRYEWVVTYSHLLLDGWSLSLMIEALAQAYAAQTAGQPYQPPVR
                     SPFIDYVSWSQATLDQGVGEHFWHSQLYGFEGVRSLSLPVPDVTEAYAEPVLINVQRSL
                     VATLEKQQRVTLATVVAGCWAVLLSRYGEGDDVLFGMTSAGRRAQIEGSESMMGLLIET
                     RPTRIEVD"
     aSModule        28975..32010
                     /complete
                     /domains="nrpspksdomains_spiDE1_Condensation_DCL.2"
                     /domains="nrpspksdomains_spiDE1_AMP-binding.3"
                     /domains="nrpspksdomains_spiDE1_PCP.3"
                     /locus_tags="spiDE1"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       28984..29022
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0034"
                     /evalue="2.00E-04"
                     /label="C1_dual_004-017"
                     /locus_tag="spiDE1"
                     /protein_end="3053"
                     /protein_start="3040"
                     /score="14.2"
                     /tool="antismash"
                     /translation="YGLTPMQEGMLYH"
     CDS_motif       29038..29157
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0035"
                     /evalue="3.60E-16"
                     /label="C2_DCL_024-062"
                     /locus_tag="spiDE1"
                     /protein_end="3098"
                     /protein_start="3058"
                     /score="51.4"
                     /tool="antismash"
                     /translation="GMYVEQLACTLTGILDEQALQDAWNDVVASNPVLRTSFHW"
     CDS_motif       29362..29421
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0036"
                     /evalue="1.90E-06"
                     /label="C3_DCL_135-156"
                     /locus_tag="spiDE1"
                     /protein_end="3186"
                     /protein_start="3166"
                     /score="20.5"
                     /tool="antismash"
                     /translation="HLLLDGWSLSLMIEALAQAY"
     CDS_motif       29734..29829
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0037"
                     /evalue="5.50E-09"
                     /label="C5_DCL_263-294"
                     /locus_tag="spiDE1"
                     /protein_end="3322"
                     /protein_start="3290"
                     /score="28.5"
                     /tool="antismash"
                     /translation="DVLFGMTSAGRRAQIEGSESMMGLLIETRPTR"
     CDS_motif       29884..29997
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0038"
                     /evalue="3.30E-07"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="spiDE1"
                     /protein_end="3378"
                     /protein_start="3340"
                     /score="22.6"
                     /tool="antismash"
                     /translation="EEAKREEAGAVSLAQIESWGGAERGARLFDTLVVVENQ"
     aSDomain        30331..31491
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiDE1_AMP-binding.3"
                     /evalue="1.00E-99"
                     /label="spiDE1_AMP-binding.3"
                     /locus_tag="spiDE1"
                     /protein_end="3876"
                     /protein_start="3489"
                     /score="325.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EEQATLRPDAIALRLGERSMSYAELTTRGRRVAAWLQRQDVGVGG
                     RVAIVGERTMETIAAMYGILLSGAAYVPLDPDWPEERKRLVIEDAQPQVFIGSTHMACG
                     SSLQISLETLEGFTDERLTGRSATPQDLAYVIFTSGSTGRPKGVMVRHADVMHLDGLQD
                     AMALSDADVWTSFHSYAFDFSVLEIWYPLMWGATVVPVPYWVSREPEAFLALICAEKVT
                     IICQTPAAFEQLISTARPGCRAGHVRWVLLGGDRYSAALFAAGDPAEFPNIANVYGITE
                     TTVITTFEPLERDRPVAIGRPFPGQRIYLLDRKKRLVPPGAVGEMYICGEGVAAGYMGA
                     EALTAQRFSDDPYQPGARMYRSGDLARFLPGGRLESIGRADHQVKIR"
     CDS_motif       30517..30555
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0039"
                     /evalue="1.90E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="spiDE1"
                     /protein_end="3564"
                     /protein_start="3551"
                     /score="11.8"
                     /tool="antismash"
                     /translation="GILLSGAAYVPLD"
     CDS_motif       30727..30786
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0040"
                     /evalue="1.90E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="spiDE1"
                     /protein_end="3641"
                     /protein_start="3621"
                     /score="32.5"
                     /tool="antismash"
                     /translation="AYVIFTSGSTGRPKGVMVRH"
     CDS_motif       31285..31374
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0041"
                     /evalue="4.20E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="spiDE1"
                     /protein_end="3837"
                     /protein_start="3807"
                     /score="38.3"
                     /tool="antismash"
                     /translation="PPGAVGEMYICGEGVAAGYMGAEALTAQRF"
     CDS_motif       31459..31521
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0042"
                     /evalue="3.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="spiDE1"
                     /protein_end="3886"
                     /protein_start="3865"
                     /score="35.0"
                     /tool="antismash"
                     /translation="IGRADHQVKIRGYRIELGEVE"
     CDS_motif       31726..31752
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0043"
                     /evalue="2.90E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="spiDE1"
                     /protein_end="3963"
                     /protein_start="3954"
                     /score="4.4"
                     /tool="antismash"
                     /translation="GKVDRKALP"
     aSDomain        31804..32010
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiDE1_PCP.3"
                     /evalue="1.40E-14"
                     /label="spiDE1_PCP.3"
                     /locus_tag="spiDE1"
                     /protein_end="4049"
                     /protein_start="3980"
                     /score="45.9"
                     /tool="antismash"
                     /translation="MAIEAIWCEVLGQEAIGVHTNFFDAGGDSIAIVRVHGLMAVLPGA
                     ERLRVVDLFQCPTIAAIAEKITSS"
     CDS_motif       31864..31893
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiDE1_0044"
                     /evalue="1.40E+00"
                     /label="PCP_mE"
                     /locus_tag="spiDE1"
                     /protein_end="4010"
                     /protein_start="4000"
                     /score="3.0"
                     /tool="antismash"
                     /translation="NFFDAGGDSI"
     gene            32106..36674
                     /gene="spiC2"
     CDS             32106..36674
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (6-418). E-value:
                     1.2e-148. Score: 487.4. Matches aSDomain:
                     nrpspksdomains_spiC2_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_KR (758-924). E-value: 1e-36. Score:
                     118.4. Matches aSDomain: nrpspksdomains_spiC2_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (1018-1082). E-value: 2.9e-20.
                     Score: 64.1. Matches aSDomain: nrpspksdomains_spiC2_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1096-1381). E-value:
                     7.6e-29. Score: 91.7. Matches aSDomain:
                     nrpspksdomains_spiC2_Epimerization.1"
                     /codon_start=1
                     /gene="spiC2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 255.7; E-value:
                     1.4e-77)"
                     /gene_kind="biosynthetic-additional"
                     /product="polyketide synthase SpiC2"
                     /protein_id="AFR69335.1"
                     /sec_met_domain="hyb_KS (E-value: 2.3e-152, bitscore:
                     497.8, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 7.5e-34, bitscore:
                     107.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.6e-14, bitscore:
                     42.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.8e-28, bitscore:
                     88.4, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTSNAIAIIGMGCRFPGASSLEQFWTNLVNGVESITSFGPTRHH
                     EAWQEVSSAGIVDNASLFDAALFGLSAREAERMDPQHRVFLECAWEALERSGYYPKQLP
                     GRVGVFAGTGFNEYLVRNIMPLAPEGDLSLLLTNDACFLSSRLAYLLGCSGPAIAVSSA
                     CSTSLVAVHLAVQSLLMGECDTAICGGVRITTPQNRPYRHEPGGIGSSDGHCRAFDSAA
                     NGTVSGNGAGVVVLRRLDDARNDGDPIAAVILGSAVTNDGAQRVGFTAPGVNGQCAAIC
                     EAQALADVSPDSIGMLEAHGTATTLGDPVEFEALSAAFRHGTTRRGFCALGSVKTNIGH
                     LDAAAGIAGLIKTVLALQHRVIPASLHFREPGSGINLQESPFFVTATARPWLEATRRAG
                     VSSFGMGGTNAHIVLESAPEPLGDTCETAEPQLLELSARSEASLHQMAQQLADHLEREQ
                     PLLADVAYTLAVSRNAYEWKTSVECTSLAEAAEALRGPLQITRSSCAAQIPRASRRRIH
                     LPATPFEHKHYWVDPPSSFAYRANPADWLYTPRLRQSMPLEQLLIDSQRNWLVLLDDHG
                     VGQRIAAALRDAGAQTVVELVYTDDTVSDVIHTQVEADWSRPLSVISLWSLAAQDSSDD
                     REVLQRHYLRPAQVLRAWADKAGGDVDVTFVVNGAFDGFGSPTAPEKAMLLGLARALRL
                     EYPSWLARVMDVEMLAQDTVECILAEATACSADDAVIHKYRSRWVETVEPVTISGGHTL
                     PIRRGGVYLVTGGNSGIGLAISRYLIDSWGAHVIALSRRGGQSGQGFTAVAANLDNIDE
                     LRQVVVSIQAEHGPINGLVHCAGMPPHALLRTATDAAVKEVFAGKFFGALNLQRVMLQM
                     PLDFVVLSSSLRAHIPAAGSGDYMAANLALEALATSWAATGARVLSIAWDTWSKVGMAA
                     TASDARFVTDELDAEGMSVEEGVKLFEAASQCGLSRVVVSTRPFSALKAHAQEAFSVGR
                     AGEVAQRVSSTRHPRPALNTVYIPARTALESQLAQIWSEILGYDTIGIKDDFFDLGGDS
                     VATLQIVARAREQGLNLETSRAFEAHTIEEFAAATRIELAEELLLGDTPLPLSAAQQWL
                     FACESGDINRFVQGVVINLPEGTDVLSVGAAIDAAVAHRRVLSVRFAQTESGWKQLLGA
                     SQSVAVEVHQYVGSPAGQLDHAIEMGGTLQRSMDIQAPLLVRAAIVSSPVESHLVIVVH
                     HLLIDASGWRILLDDICARVADLGRATDVPDEAFLQWVIHLDGIAQDAKINEEEAAYWA
                     SLDLPDQDFPALRRKGSTGSLTSTLSVAQTRVLTSSRKSIEALLATAVAYALRPVAMSD
                     RILIDIESLGRGWSRVPQDVSRAMGWFTAIHPLVIDTAQGIYAAAAQAATLVPQARHRA
                     VAYTMLRQHAPDLLPPVLRSDAPVSVVFFPAPTTVPGWSIASILPPPEGMPAPHAVALA
                     ATIENGALTLQWHGQTDPFEGMALATLVSRTMQGLRELVAGGKDQMSALMTQLDMSGVD
                     DE"
     aSDomain        32124..33359
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiC2_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="1.20E-148"
                     /label="spiC2_PKS_KS.1"
                     /locus_tag="spiC2"
                     /protein_end="418"
                     /protein_start="6"
                     /score="487.4"
                     /tool="antismash"
                     /translation="IAIIGMGCRFPGASSLEQFWTNLVNGVESITSFGPTRHHEAWQEV
                     SSAGIVDNASLFDAALFGLSAREAERMDPQHRVFLECAWEALERSGYYPKQLPGRVGVF
                     AGTGFNEYLVRNIMPLAPEGDLSLLLTNDACFLSSRLAYLLGCSGPAIAVSSACSTSLV
                     AVHLAVQSLLMGECDTAICGGVRITTPQNRPYRHEPGGIGSSDGHCRAFDSAANGTVSG
                     NGAGVVVLRRLDDARNDGDPIAAVILGSAVTNDGAQRVGFTAPGVNGQCAAICEAQALA
                     DVSPDSIGMLEAHGTATTLGDPVEFEALSAAFRHGTTRRGFCALGSVKTNIGHLDAAAG
                     IAGLIKTVLALQHRVIPASLHFREPGSGINLQESPFFVTATARPWLEATRRAGVSSFGM
                     GGTNAHIVLESAP"
     aSModule        32124..36248
                     /domains="nrpspksdomains_spiC2_PKS_KS.1"
                     /domains="nrpspksdomains_spiC2_PKS_KR.1"
                     /domains="nrpspksdomains_spiC2_PCP.1"
                     /domains="nrpspksdomains_spiC2_Epimerization.1"
                     /incomplete
                     /locus_tags="spiC2"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       32568..32615
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC2_0001"
                     /evalue="1.10E-03"
                     /label="PKSI-KS_m3"
                     /locus_tag="spiC2"
                     /protein_end="170"
                     /protein_start="154"
                     /score="11.6"
                     /tool="antismash"
                     /translation="GPAIAVSSACSTSLVA"
     CDS_motif       32994..33038
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC2_0002"
                     /evalue="4.70E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="spiC2"
                     /protein_end="311"
                     /protein_start="296"
                     /score="9.8"
                     /tool="antismash"
                     /translation="LEAHGTATTLGDPVE"
     CDS_motif       33099..33143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC2_0003"
                     /evalue="6.70E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="spiC2"
                     /protein_end="346"
                     /protein_start="331"
                     /score="12.1"
                     /tool="antismash"
                     /translation="GSVKTNIGHLDAAAG"
     CDS_motif       33831..33887
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC2_0004"
                     /evalue="1.80E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="spiC2"
                     /protein_end="594"
                     /protein_start="575"
                     /score="1.4"
                     /tool="antismash"
                     /translation="GVGQRIAAALRDAGAQTVV"
     aSDomain        34380..34877
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiC2_PKS_KR.1"
                     /evalue="1.00E-36"
                     /label="spiC2_PKS_KR.1"
                     /locus_tag="spiC2"
                     /protein_end="924"
                     /protein_start="758"
                     /score="118.4"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GVYLVTGGNSGIGLAISRYLIDSWGAHVIALSRRGGQSGQGFTAV
                     AANLDNIDELRQVVVSIQAEHGPINGLVHCAGMPPHALLRTATDAAVKEVFAGKFFGAL
                     NLQRVMLQMPLDFVVLSSSLRAHIPAAGSGDYMAANLALEALATSWAATGARVLSIAWD
                     TWS"
     CDS_motif       34383..34481
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC2_0005"
                     /evalue="2.60E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="spiC2"
                     /protein_end="792"
                     /protein_start="759"
                     /score="26.5"
                     /tool="antismash"
                     /translation="VYLVTGGNSGIGLAISRYLIDSWGAHVIALSRR"
     CDS_motif       34722..34829
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC2_0006"
                     /evalue="3.40E-08"
                     /label="PKSI-KR_m4"
                     /locus_tag="spiC2"
                     /protein_end="908"
                     /protein_start="872"
                     /score="26.0"
                     /tool="antismash"
                     /translation="LDFVVLSSSLRAHIPAAGSGDYMAANLALEALATSW"
     aSDomain        35160..35351
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiC2_PCP.1"
                     /evalue="2.90E-20"
                     /label="spiC2_PCP.1"
                     /locus_tag="spiC2"
                     /protein_end="1082"
                     /protein_start="1018"
                     /score="64.1"
                     /tool="antismash"
                     /translation="ESQLAQIWSEILGYDTIGIKDDFFDLGGDSVATLQIVARAREQGL
                     NLETSRAFEAHTIEEFAAA"
     aSDomain        35394..36248
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiC2_Epimerization.1"
                     /evalue="7.60E-29"
                     /label="spiC2_Epimerization.1"
                     /locus_tag="spiC2"
                     /protein_end="1381"
                     /protein_start="1096"
                     /score="91.7"
                     /tool="antismash"
                     /translation="PLPLSAAQQWLFACESGDINRFVQGVVINLPEGTDVLSVGAAIDA
                     AVAHRRVLSVRFAQTESGWKQLLGASQSVAVEVHQYVGSPAGQLDHAIEMGGTLQRSMD
                     IQAPLLVRAAIVSSPVESHLVIVVHHLLIDASGWRILLDDICARVADLGRATDVPDEAF
                     LQWVIHLDGIAQDAKINEEEAAYWASLDLPDQDFPALRRKGSTGSLTSTLSVAQTRVLT
                     SSRKSIEALLATAVAYALRPVAMSDRILIDIESLGRGWSRVPQDVSRAMGWFTAIHPLV
                     IDTA"
     CDS_motif       35763..35828
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC2_0007"
                     /evalue="4.60E-06"
                     /label="NRPS-E2"
                     /locus_tag="spiC2"
                     /protein_end="1241"
                     /protein_start="1219"
                     /score="19.2"
                     /tool="antismash"
                     /translation="LVIVVHHLLIDASGWRILLDDI"
     CDS_motif       36189..36239
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiC2_0008"
                     /evalue="1.00E-05"
                     /label="NRPS-E5"
                     /locus_tag="spiC2"
                     /protein_end="1378"
                     /protein_start="1361"
                     /score="18.0"
                     /tool="antismash"
                     /translation="DVSRAMGWFTAIHPLVI"
     gene            36664..37839
                     /gene="spiF"
     CDS             36664..37839
                     /codon_start=1
                     /gene="spiF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 283.9; E-value:
                     3.3e-86)"
                     /gene_kind="biosynthetic-additional"
                     /product="acyl CoA dehydrogenase SpiF"
                     /protein_id="AFR69328.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 9.4e-12, bitscore:
                     35.8, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.5e-20, bitscore:
                     63.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5.9e-32, bitscore:
                     101.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNDRVAAFSAVEAALAAPEAALAGGDFATVEQLMSDIRGANRAR
                     GLWLPQLSRVNGGSGLDLLELVEVGEVLGRSPLGHYAVNYQAPDAGNIDILLEYATSEQ
                     KRRWLDPLLQGKVRSCFAATEPDRAGSNPSALATKAVFKEGAWHLTGRKWFASGADRAA
                     FAIVLAVTDETAPLHARTSTFIVPTDAPGYRHVRNIRVMGDEGCGWASHGEIELDDCRV
                     ETDALLGEPGAGFVVLQSRLATGRLHHCARWIGVCERAFAIMCRRASRRELAPGEFLSS
                     RQTVQNWIAESRASIDAARLLVAQAASRLQKRHERAQVDISIAKFFVAGVTQTVLDHAL
                     QIQGALGVSGDTIVNVFWRHERAGRIYDGPDEVHKALVARHALAAFRGEPR"
     gene            37836..38804
                     /gene="spiG"
     CDS             37836..38804
                     /codon_start=1
                     /gene="spiG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /product="phosphotransfearse SpiG"
                     /protein_id="AFR69336.1"
                     /sec_met_domain="APH (E-value: 6.3e-38, bitscore: 121.1,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLQVAHSTMTALGSPGAAALATRIGAGRSSETYLVQANDRDLIT
                     YVLPSGSAREAQRRFAVLAQIAERYRLAPKPLAVVEACDEGRTLLVMERLPGVLPTACG
                     SLSPDMVRRLCAGFISALASLHAIEIAPVDRPPDYLRRSIGDWERRWCEEEAAGAHDDF
                     KSVVRWLADNLPDQVASAFVHNDFKLDNILVDPGDPARVVGVVDWELATIGHPLADLGV
                     ALAYWIERRDSSLLRLEAPGPSCALGAPTRQELVELYSAASGREVLHASYWYVYGLLRL
                     AVITQQLVLRHKDGGQSVPRGLLIVRSLLAHASNTCGSGRL"
     gene            38801..41020
                     /gene="spiE2"
     CDS             38801..41020
                     /NRPS_PKS="Domain: Condensation_DCL (5-291). E-value:
                     4e-75. Score: 244.6. Matches aSDomain:
                     nrpspksdomains_spiE2_Condensation_DCL.1"
                     /NRPS_PKS="Domain: PP-binding (441-502). E-value: 1.1e-13.
                     Score: 43.4. Matches aSDomain:
                     nrpspksdomains_spiE2_PP-binding.1"
                     /NRPS_PKS="Domain: Thioesterase (521-734). E-value:
                     1.6e-21. Score: 69.6. Matches aSDomain:
                     nrpspksdomains_spiE2_Thioesterase.1"
                     /codon_start=1
                     /gene="spiE2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     225.9; E-value: 1.7e-68)"
                     /gene_kind="biosynthetic-additional"
                     /product="nonribosomal peptide synthetase SpiE2"
                     /protein_id="AFR69337.1"
                     /sec_met_domain="Condensation (E-value: 3.5e-50, bitscore:
                     160.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.1e-14, bitscore:
                     43.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.7e-12, bitscore:
                     37.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKANIQDIHGLAPSQHGMLLESTNGLTQGDMFIEQSVLLVRGKLD
                     TPRFLSAVEQIATIHSSLRSCFAWEGETPLHVVFDKVRPVVEWEDWQSKEGADDRQTLE
                     AWLAADRSRGLAVNRAPLWRFTVIRCAEEVHRVIWTHHHLITDGWSIAVVLNDLLDHYK
                     GLHPVPAARPLRDYIDWVEAQDRGQAIAFWRQRVQRLPRLPPMPPRAHEHCFVEIDGID
                     VRGILDTARKQKVAFATVAFAAWALVLRASRSSDEVVFGITVHGRPAEIVGVERMVGPF
                     IATFPMYLQMAHMSTTEELLHQIEQQQSEQRPFEYLSAAEVHQAGGIATRLYDSLVVVE
                     QIPQHSAMATGGISVSAESGNGARSHHPLLLRFSQDGMARLMYNKKFFDDETASGLVSL
                     LRQAAVRLASNDGLVSLDGAMAFYAPIKPRPVRMPRNQEEHIVLSLARTLFGEHATLDD
                     NFIDLGGHSLLAVQFIQRIAHETGVQLPITQFLQDDRLSSLAKALGDSQAGVVDVSHPR
                     ILFVPGNPGTVLYASRLSVHLVDWRLHGLEAPGLDGSQPPLATVEALAEHHLASLSVDD
                     NPTVIIGHSFGGWVAFEMGLRLQARGREAVVILLDTVSPYRLLSRGDVSDEGLRAEVEH
                     LKIRAGSAGINAHITPAVFEVYVAARRAIYAPAEQARFPMMLFRASQTRPEDTWDKTAP
                     DYGWGELCQQLHVDTIEGDHLSIMVDPATEVLARRIERWLYQLSR"
     aSDomain        38816..39673
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiE2_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="4.00E-75"
                     /label="spiE2_Condensation_DCL.1"
                     /locus_tag="spiE2"
                     /protein_end="291"
                     /protein_start="5"
                     /score="244.6"
                     /tool="antismash"
                     /translation="QDIHGLAPSQHGMLLESTNGLTQGDMFIEQSVLLVRGKLDTPRFL
                     SAVEQIATIHSSLRSCFAWEGETPLHVVFDKVRPVVEWEDWQSKEGADDRQTLEAWLAA
                     DRSRGLAVNRAPLWRFTVIRCAEEVHRVIWTHHHLITDGWSIAVVLNDLLDHYKGLHPV
                     PAARPLRDYIDWVEAQDRGQAIAFWRQRVQRLPRLPPMPPRAHEHCFVEIDGIDVRGIL
                     DTARKQKVAFATVAFAAWALVLRASRSSDEVVFGITVHGRPAEIVGVERMVGPFIATFP
                     MYLQM"
     aSModule        38816..41002
                     /domains="nrpspksdomains_spiE2_Condensation_DCL.1"
                     /domains="nrpspksdomains_spiE2_PP-binding.1"
                     /domains="nrpspksdomains_spiE2_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="spiE2"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       38888..39007
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiE2_0001"
                     /evalue="1.40E-07"
                     /label="C2_DCL_024-062"
                     /locus_tag="spiE2"
                     /protein_end="69"
                     /protein_start="29"
                     /score="23.8"
                     /tool="antismash"
                     /translation="DMFIEQSVLLVRGKLDTPRFLSAVEQIATIHSSLRSCFAW"
     CDS_motif       39221..39286
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiE2_0002"
                     /evalue="3.90E-08"
                     /label="C3_DCL_135-156"
                     /locus_tag="spiE2"
                     /protein_end="162"
                     /protein_start="140"
                     /score="25.8"
                     /tool="antismash"
                     /translation="HHHLITDGWSIAVVLNDLLDHY"
     CDS_motif       39572..39661
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiE2_0003"
                     /evalue="1.20E-13"
                     /label="C5_DCL_263-294"
                     /locus_tag="spiE2"
                     /protein_end="287"
                     /protein_start="257"
                     /score="43.4"
                     /tool="antismash"
                     /translation="VVFGITVHGRPAEIVGVERMVGPFIATFPM"
     CDS_motif       39716..39820
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiE2_0004"
                     /evalue="2.20E-07"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="spiE2"
                     /protein_end="340"
                     /protein_start="305"
                     /score="23.2"
                     /tool="antismash"
                     /translation="QQQSEQRPFEYLSAAEVHQAGGIATRLYDSLVVVE"
     aSDomain        40124..40306
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiE2_PP-binding.1"
                     /evalue="1.10E-13"
                     /label="spiE2_PP-binding.1"
                     /locus_tag="spiE2"
                     /protein_end="502"
                     /protein_start="441"
                     /score="43.4"
                     /tool="antismash"
                     /translation="VLSLARTLFGEHATLDDNFIDLGGHSLLAVQFIQRIAHETGVQLP
                     ITQFLQDDRLSSLAKA"
     aSDomain        40364..41002
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiE2_Thioesterase.1"
                     /evalue="1.60E-21"
                     /label="spiE2_Thioesterase.1"
                     /locus_tag="spiE2"
                     /protein_end="734"
                     /protein_start="521"
                     /score="69.6"
                     /tool="antismash"
                     /translation="PGNPGTVLYASRLSVHLVDWRLHGLEAPGLDGSQPPLATVEALAE
                     HHLASLSVDDNPTVIIGHSFGGWVAFEMGLRLQARGREAVVILLDTVSPYRLLSRGDVS
                     DEGLRAEVEHLKIRAGSAGINAHITPAVFEVYVAARRAIYAPAEQARFPMMLFRASQTR
                     PEDTWDKTAPDYGWGELCQQLHVDTIEGDHLSIMVDPATEVLARRIERWL"
     CDS_motif       40532..40594
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiE2_0005"
                     /evalue="5.90E-08"
                     /label="NRPS-te1"
                     /locus_tag="spiE2"
                     /protein_end="598"
                     /protein_start="577"
                     /score="25.2"
                     /tool="antismash"
                     /translation="PTVIIGHSFGGWVAFEMGLRL"
     gene            41103..42008
                     /gene="spiH"
     CDS             41103..42008
                     /codon_start=1
                     /gene="spiH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176:alkyl hydroperoxide reductase subunit (Score:
                     249.4; E-value: 1.1e-75)"
                     /gene_kind="biosynthetic-additional"
                     /product="FAD-dependent disulfide oxidoreductase SpiH"
                     /protein_id="AFR69338.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9.9e-21, bitscore:
                     64.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTELSLVNFDFIVIGGSYAGQSAAMQLARARRRVLVMDVGVRRN
                     RFSRTLHGLPGQEGRSPDVIAQEGRAQIIAYPNVQWLEEEATSAERTKAGFVVRAQSGQ
                     GFFAPNVVLATGVEDDLPPVDGLAQRWGRSVFHCPYCHGYELNQGYIGVLAVDEVAYQL
                     ALMMLDWGTVILLTDGRFEPDEAQRKTLAECGVVIESQRVLRIVDTATVELDDGRKIVL
                     DGLFCASHTRMASPIAAQLGCAFEEGAMGPYICTSETMETSVPGVFACGDMVRMGGTVG
                     LAVGSGAHAGLAAHRASAQR"
     gene            42066..42971
                     /gene="spiI"
     CDS             42066..42971
                     /codon_start=1
                     /gene="spiI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066:alpha/beta hydrolase domain-containing protein
                     (Score: 255.4; E-value: 1.1e-77)"
                     /gene_kind="biosynthetic-additional"
                     /product="esterase/lipase SpiI"
                     /protein_id="AFR69339.1"
                     /transl_table=11
                     /translation="MSWQNWCISWLLRLKVKPLIAKPGLSVQDMRTHSDKGVRLVRPPK
                     GWHIRESTEASGEWVEPQDPVQRDRLHRVVMYLHGGGYCFCSAKTHRGIACALASGAEA
                     RTFSLDYRLAPEHPFPAAVNDALAAYRQLLAEGVCPARIVICGDSAGGGLALAMLLSLR
                     DAGEPMPVGAVLFSPWTDLAATGGSLTTNNPSDVMLTGAAVARFSRHYLNDTPADHPIA
                     SPLYAQFAGLPPLFIQASDTEVLLDDAVRVAEKARLAQVAVNFKVWPRLPHAWPTMTPF
                     LPEAKEAVKEAVDFIRSVTG"
     gene            43182..44033
                     /gene="spiJ"
     CDS             43182..44033
                     /NRPS_PKS="Domain: Thioesterase (37-262). E-value: 6.9e-56.
                     Score: 182.0. Matches aSDomain:
                     nrpspksdomains_spiJ_Thioesterase.1"
                     /codon_start=1
                     /gene="spiJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 289.6; E-value: 2.3e-88)"
                     /gene_kind="biosynthetic-additional"
                     /product="type II thioesterase SpiJ"
                     /protein_id="AFR69340.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.7e-13, bitscore:
                     40.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHGSWRRCGYIVLARSHAMTIGSFDSVPGTSTGQTRVKLFCLPYA
                     GGSAAIFRDWPSRLSSEIEVVPLHLPGRGRRMREALLHDLGEIANQVVDAIAPLLEKPY
                     VLFGHSMGACLAFEVARRLRASGLPKPACLIVSGHRAPHLPASRSLLHGLPDDEFIDEV
                     MRLNGTPPEILKHPEVLDLILPILRADFEAVETYRMTPEPPLACRIVALGGDNDPGMDS
                     DAVASWGIHTTSSFYYQMLPGDHFFLHGSAEQMFALINQELRSVLLQVRSGQQGVAIEP
                     TG"
     aSDomain        43293..43967
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiJ_Thioesterase.1"
                     /evalue="6.90E-56"
                     /label="spiJ_Thioesterase.1"
                     /locus_tag="spiJ"
                     /protein_end="262"
                     /protein_start="37"
                     /score="182.0"
                     /tool="antismash"
                     /translation="KLFCLPYAGGSAAIFRDWPSRLSSEIEVVPLHLPGRGRRMREALL
                     HDLGEIANQVVDAIAPLLEKPYVLFGHSMGACLAFEVARRLRASGLPKPACLIVSGHRA
                     PHLPASRSLLHGLPDDEFIDEVMRLNGTPPEILKHPEVLDLILPILRADFEAVETYRMT
                     PEPPLACRIVALGGDNDPGMDSDAVASWGIHTTSSFYYQMLPGDHFFLHGSAEQMFALI
                     NQE"
     CDS_motif       43485..43550
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiJ_0001"
                     /evalue="8.50E-11"
                     /label="NRPS-te1"
                     /locus_tag="spiJ"
                     /protein_end="123"
                     /protein_start="101"
                     /score="34.2"
                     /tool="antismash"
                     /translation="KPYVLFGHSMGACLAFEVARRL"
     gene            44153..45295
                     /gene="spiP"
     CDS             44153..45295
                     /NRPS_PKS="Domain: PKS_AT (5-288). E-value: 1.9e-52. Score:
                     170.4. Matches aSDomain: nrpspksdomains_spiP_PKS_AT.1"
                     /codon_start=1
                     /gene="spiP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 363.6; E-value: 3.5e-110)"
                     /gene_kind="biosynthetic-additional"
                     /product="malonyl CoA acyl transferase (MCAT) SpiP"
                     /protein_id="AFR69341.1"
                     /sec_met_domain="PKS_AT (E-value: 5.3e-53, bitscore: 170.4,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITTFMFPGQGSQAKGMGAGLFDRFKELSAQADRVLGYSIKELCL
                     VDPGGRLSLTQFTQPALYVVNALTYYARLEDDATPADFVVGHSLGEFNALLAAGCFDFE
                     TGLQLVKKRGELMGQISGGAMAAILNANKNDIELTLARSGLDDIGVANYNTPSQFVISG
                     PVEQIEASEALFQNAPMRYLRLNTSGAFHSKLMQPAADVFAAFLDAFTFVSPIIPVFAN
                     FSARPYESNQIADGLAKQMASPVRWCESVQHLLEFAAGSGQEASFEELGHGEVLTRLVH
                     AIRRQTPVAENRVVSDASALDKRGQPNLLPVLGTQTSSAHEKVTAWNLNCPVGTKVRSL
                     LIDYPSLETCTEAMVLFGHRPVVYMKGYNGYFDIDEVMGV"
     CDS_motif       44165..44215
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiP_0001"
                     /evalue="2.00E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="spiP"
                     /protein_end="21"
                     /protein_start="4"
                     /score="20.0"
                     /tool="antismash"
                     /translation="FMFPGQGSQAKGMGAGL"
     aSDomain        44168..45016
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spiP_PKS_AT.1"
                     /evalue="1.90E-52"
                     /label="spiP_PKS_AT.1"
                     /locus_tag="spiP"
                     /protein_end="288"
                     /protein_start="5"
                     /score="170.4"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="MFPGQGSQAKGMGAGLFDRFKELSAQADRVLGYSIKELCLVDPGG
                     RLSLTQFTQPALYVVNALTYYARLEDDATPADFVVGHSLGEFNALLAAGCFDFETGLQL
                     VKKRGELMGQISGGAMAAILNANKNDIELTLARSGLDDIGVANYNTPSQFVISGPVEQI
                     EASEALFQNAPMRYLRLNTSGAFHSKLMQPAADVFAAFLDAFTFVSPIIPVFANFSARP
                     YESNQIADGLAKQMASPVRWCESVQHLLEFAAGSGQEASFEELGHGEVLTRLVHAIRRQ
                     TP"
     CDS_motif       44249..44314
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiP_0002"
                     /evalue="3.80E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="spiP"
                     /protein_end="54"
                     /protein_start="32"
                     /score="-2.4"
                     /tool="antismash"
                     /translation="DRVLGYSIKELCLVDPGGRLSL"
     CDS_motif       44396..44503
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spiP_0003"
                     /evalue="2.10E-14"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="spiP"
                     /protein_end="117"
                     /protein_start="81"
                     /score="45.5"
                     /tool="antismash"
                     /translation="DFVVGHSLGEFNALLAAGCFDFETGLQLVKKRGELM"
     CDS             45705..46709
                     /codon_start=1
                     /note="orf+1"
                     /product="luxR family transcriptional regulator"
                     /protein_id="AFR69342.1"
                     /transl_table=11
                     /translation="MAQRDDYRVKSPLEMLNVFNLCVLELARLARSRAGSHFIAEGLQT
                     FRPLVPFTSAWWGEMSNTDAKAAPQSWMHGRINLPESFAAEWSTIAGRDSFAHDTLNRP
                     GKVVRDSEFTDPDDQVNVFARRYDLYHLMCITFELPESGLMFFVCLYRGLDAPAFNETE
                     DGLFSAFCDHLLQLWRFQVQDMIRFDTDNGATDFGVARMDGSLLYVGARLCAAIERELP
                     GWSGSMLPEQVITQLHDAPGVVRLGRSSLTLSPHGEHVILSLEVPSGGAALAPRERTAA
                     MLFAAGHSYKEIAKMLSLSPATVRTYLRNCYLQLGVKSKVELGSVLRAVVRRD"
ORIGIN
        1 tgatcgttcg agagaggact taagcgggaa agtactttcg cgcctcctcg gtggtatagc
       61 gcaggaagat ctgcacagcc tgcggaatca ggcgtcgtgt gagtagaaaa gcatacagcg
      121 acatgttctg cagggtatag ccggtcagag tatgcccccg ttttccgttc tcggacggat
      181 ggagccagtc gggtaagcgc tcaaatggta ctgcgccgtg cgtgaggtag gcatcattga
      241 cccgtgcttg aaaaagggcc tggatgcaac ggattgcgtc caggcccctt gatcgctacg
      301 ggtgtttttt tcaggcaaca atgtcagtga aggtggcctg gccgacggtg gtgacgagga
      361 agtccgccac gccttgaccg gagaagtcga tggccagggt gcctaggttg gtggccgagg
      421 caaagctcaa caccgcatcg cccgccgcgc cggtgaaggc gttgacgtaa tgcaggccgg
      481 cgccttgggt gatgcccgtc aggtcgatct tgtcgctgcc actggtgaag tcgaggatct
      541 ggtctgccgc ccccggtttg gagtcagagc tggcgccaaa cacgaaggtg tcagccccgg
      601 cgccacccca cagttgatcc gttccgccac caccgtagag cacgtcattg cccgcgccac
      661 ccttgagtac gttatccgcg gtgttgccca ccaacaggtc gttacccgag ccgccgatag
      721 cgttttccac ggtcacgccc ttggcgatgg agacgttgcc caccaggccg ccgacattgg
      781 agaacgaacc ttcattgagg ttgatttgct gggctttgct gaagccggag aagtccaggg
      841 tgtcgttgcc gccgccgtcc cagacggcga acaccaattt gtcggtggcg gaggtggcac
      901 tcaggtaatc acgatcggtg ttggagttga agtcgtaagt ggtgtctgtg gcgcgggtgt
      961 cgtagttggc gccgtagtgc ttctggatcg cggcgatgtc atcgaccagc ggcccagctg
     1021 aataagcgcg ggagaagttc tggtcggtgt tgctctcgtg tagccacggg tgtcttcggc
     1081 ataggacgcg cttgtcgagt aagtcggcgc gaccgtatcg ctggcgttgt agctgccagg
     1141 gtgagcgagc cccagggcat gcccgatttc gtgggtcagg gtctggcgtc cgtagttacc
     1201 gttagccggg gtgctgttga cctggtagtc ctggctgatc ttgtaccagg tttcgctggt
     1261 gccgctgctg tttggatact cgccgaaggc cgcgcctttg ctgtccacct gggtaaaagt
     1321 tgaactaggc tgcgcgagcg catcattaga tgaggtgaag agttttttaa ggtttgccat
     1381 atccctatat ccttgagcta taagttgaaa aaggttttaa cggctattgg ctcttgcaat
     1441 cccccgtgct gattagccct cgggcaaaaa aatactgaca ctggagggag tggctgtcca
     1501 aaagtaatct ggcacgggcc gctgccctgt gatcggggta gttgtctttt tctttttgaa
     1561 tcagcaggct ggcaaggcaa gggggcttat acttaattat taaatagagg tgggcctaaa
     1621 ttttgtaagg aggcgaacgt cacggcactt caggttactc atttaacgac taacgactta
     1681 accaaatgat atgaaggaaa cattgatgtc ttatagtgtt ccaacgtcgt ggtagttgta
     1741 ttgtcggtgc aattacattc atcaatgacg gcatttggtc tcgccagggg ccgaggtttc
     1801 gacgtccacg ggttccccat ccaggctgtt cagtcactga gcgcgcggcg gacagcaggt
     1861 gcgaccttgg gggcagtggg ctctttgccg gggctgtcat attcactggt ttactttgta
     1921 acaaatcaat tcattctcgc ccaggtcatt tgcccccgat atagaggaca cgtcaggccg
     1981 gtatcgacaa aacattcctg ccctttattc atctttgcgc ttgttatcaa gcaacagtaa
     2041 atacaaggcc tggcagccgt tatcgttcat tcaggggggg aaggtactta tgagctccat
     2101 cgcctgatta tgaaaataat ccgagtactt ccttgacagt gttctgaagc gctcaaggtg
     2161 actcattgat tattaaatta gacagcaagt tacaggttat gccagtttta tcgggacgcc
     2221 aatgacgtga gcgcctgtat ccttttcgaa ggatgctcgt cgtctattgg ttttttttca
     2281 gcgattaaca aggacgtcta tgtcaaagct aaaagagaac gcattttctg ctatcggcca
     2341 ggccagtaag gcctacgatc aggtcgatgg tttcagccat cggtatgacc gtggcggggt
     2401 cgatctggtg aacgacaagc cttcgttcac cgccgatcag gccgcggacg aattgctgcg
     2461 taaaggcgcg agttggcacg atcagaacgg ggacggaaaa atcagcctca gttacacttt
     2521 cctgacgtcc cagcctgcgg atttcaaccc gggcctgggt acgttcagcg agttcagcgc
     2581 gctgcaaaaa gctcaggcag tccttgcgct gcagtcttgg tctgatgtgg ccaatgtgac
     2641 ctttgtcgat gccccaggcg gtgtcgatgg tcaactgacg tttggcaact acagcagttt
     2701 tgccggtggc gcagccttcg cgtacctgcc aaccggtggt tcgcgtgacg gccagtcctg
     2761 gtacatggtc aatgaccaat acccgaccaa caccacaccg gacaacggca actacggtcg
     2821 acaaaccctg acccacgaaa tcggtcactc cctgggcctg tcccaccccg gcaactacaa
     2881 cgccggcaat ggcagcccga cctacaacga tgtcacgtat gccgaggaca cacgcggcta
     2941 tagcctgatg agctactgga gcgaaagtaa tacccaacag aacttcagtg gtgcttattc
     3001 atccgcgccg ttgatggacg atatcgtagc gatccagaag ctctatgggg ccaacctgga
     3061 tacccgcgac ggcaacaccg tttacggttt caattcaaac accggccgcg atttctacac
     3121 agcaaacacc tccagcgaca agctggtgtt ttcggtgtgg gacggcggcg gcaacgacac
     3181 cctggacttt tccggtttca gccagaacca gaagatcaac ctcactgcag gttcgttctc
     3241 cgatgtgggt ggcctggtgg gtaacgtctc tattgctcat ggggtgacgc tggaaaatgc
     3301 catcggtggc gttggcgacg atctgctgat tggcaattcg gctgccaaca tcctcgaggg
     3361 cggtgcgggg aacgacatcc tctatggcgg tggcggtggg gataccttgt ggggtggtgc
     3421 cggagcagac acctttgtgt tcggccaggc cagtgactcg acgatgaccg cgccggcctg
     3481 gatcatggac ttcaccagtg gcgaggacaa aatcgacctg tcaggcctgt tcgcttcagt
     3541 tggcgcgacg ttgaacattg tgaccggctt cacgggccat gccggggacg ccatcctgac
     3601 ctacttccag cagaccaatc agaccagcct gatggttgac cttaccggca gtggccttgt
     3661 agattttgcg gtaggcaccg ttgggcaggc cgcgatgact gatatcgtcg cctgagccaa
     3721 gtcaggcata agaggcaaaa aaagcgaagt cagatgaatg gcttcgcttt ttatgtttgg
     3781 ggcgttttgc ttcaggcaac aaggtcagtc attgcagtct ggccaggtaa tgttggtcag
     3841 gttgatgtcg tcactgccag cgctattcgg atactcgccg caggcggagc ctttgctgaa
     3901 atggtggcag ctctaaattt ttaatggggg aaaacgttac gttctttcgg ggtgtttatt
     3961 taaggcctga ccaattaacg aaatgataca tgaggcgcct tcactcccaa gaagtacgag
     4021 ttggggggag tgtcgggcgt gcgaactggg gcttgggttc cagcgagtag gatttcggcc
     4081 gccgccaatc ttcggttaat acgggtcgac caacgccagc aagccacttg attcatctcg
     4141 gcaaggagcc gtttcttgtg ctcgccaggg tattcaaaac tggaaacgct gagctggctc
     4201 gtagcgcgct cgggtcagat atcgaggccg tattcagcac gctcgcagac ttgctcggag
     4261 cgtccctaga tggatttatg gcaggatttc agtttgcttt cataaaaatg aaaaggcatc
     4321 cagaaaaaat gtacaaaatt ccttgcatcg ttcaataacc agtattagat tccagcctca
     4381 ttgattgaac gtgtgtgaaa tttcctacat ggacagtcgg aattaccaag tcgaaatgtt
     4441 tggcaatatt taatgcgcag gctctcgggg atctgactta tggggggagc attgattttt
     4501 tgttgactcg cgagatcgca aaaggattgc ttgcctgaat gaaaaaaact gtctgcaagg
     4561 tgcttctgta ctgagcggtt agatctttgt ttttggaagg ttaagtagtt tttagtagtg
     4621 ggggatgaag tatgactgct gcgtgagggc tgcgtaaaat taatggattg ttcaatgcag
     4681 ttgctggaca tcgatcggtg tttaaggggt gctcaacagc ctatggtaag gctgtcaagg
     4741 aactctgcgg gacttaattt agtgttgtgc ccctcaggga atgggtagga aggatagttt
     4801 taatatttgt tctagtgggt agtctgtaat aggaaaggtt cgtgagtttt ggtagttggt
     4861 attcgggttt taataagggc gcttgatgga gctatgcgca ttgcgaggaa tatattatga
     4921 gtcgtcagtt tgatgtggcg gtgctgaaga cctttcatgc tgtggcacgt tttggccggt
     4981 tcaaggatgc agcaatatat gtcaaccgca gtgcttcagc agttactgtt caaattcaca
     5041 agcttgaaga gcaggttggg catcgactat ttcatcgcaa caataatgtc gttgagctga
     5101 ccccgtttgg gcgcaagttg ctcgggtata cgaccgattt cttggttgcc catgaccggc
     5161 taataacatc cttagctcca caacgtcttt tgctcaagtt gaggcttggg gtgcccgatg
     5221 tctacgtggc aaaatttatg aaagacctgc ttccgacgtt tactctgagt aatcctatgc
     5281 tggagttgga ggttgaagct cgttccagtg gggagttgtt tgatctcttc tcacagcaga
     5341 tgcttgatat caccctgttg gttgcttctc aatgcccgca ggatggggag tttctctgct
     5401 caacgtcacc ccgctgggtt gtttcaccag cattcaaata cgacccaggc cagccattgc
     5461 ccgtttctgt acatcttcat ggttgcccat accgtgaggc ggctattcga gcgctcaaga
     5521 cggcaggcat aaaatttcga atatttatgg aaagttctag ttttactgcc gttgaagctt
     5581 cagtgatgag cggattgtcc atcggggtga tggaaaatgg tttagtcgat cggcgggcca
     5641 acaggagtgt gcagggaatc gagcttcccg acttggatga gcatttcata tgtttattaa
     5701 cgaacagtaa tagtcctgcg gcggtgtcct tgagaaatgc tatttttgag caattttcca
     5761 agagtgagtt tttgctggat gtcgtatagt aagtttgaat ttttatgtag gctcacggtt
     5821 gattaaagtc aattttccgc tgtgttgaaa acattggatt tatgaggcct tagtgggccg
     5881 ctaactaagt gctctgatgt cttgtctccg agctctgtag ggctcgttct tttgtgtgtg
     5941 agtatttata ctgtcactta ttgtataagt taaccgctcg ccaatatcgc aggttcgatg
     6001 agtatcgatc atccatgatt catggggaat gaagtttttg tttgatcttt ttcacggcat
     6061 gtgaaaaagg ttgatcgtgt tttgtttttt aaaagcatta attttgtttt atgttattgg
     6121 ctcgtgtcat tggattacgg attcattttt tttcaattga gtgtgattgg atgtccggaa
     6181 ttttgctgct acgctgcatc gagttcggtt gtgttgtcat ttgggcgttt gattatctgc
     6241 tgtgctcaag gactctatat atagagactc gtagaaccgt tatggatttg tttttcatgg
     6301 agctatcacc atgcaatcag ttcaggttag ggagcgcaga aaagtatcaa gatctgtgaa
     6361 gtatttattg cctttttggg gaggggctcg actacttgtg gtatttgaat tggatagatt
     6421 tagatcctcc tattggccca gtcaggtgcg ggagagcgct gactctatcc ttgttgaatt
     6481 aaatgctcgt cgatctatat cgggttctgg ggataatcaa ataacgaacg aagttttagt
     6541 tgtttttact gccctgacta gagcagtaaa gctgcttctt tcgacttgtt tttggctatc
     6601 cagacaaata actaaacgtg aggcgcagtt atgaaccccc cttacaacga acaacctcgt
     6661 gttctacctc gtctttctct gtcagagcaa ttgatgttac gcgccgatgc cttcccggac
     6721 cttctggcat tcgcttcgct ggatcaatcg aagggtgtct cgctgacaaa tgcagacctg
     6781 tgtgaacgtg cagccgctat tgcgtatcgc ctggcaaaat gcacctcgcc cggcgatcgc
     6841 gtattgctgt cttatgacca tcctcttgat tttattccgg cattttttgg ttgttgtttc
     6901 tccggcacga ttgccgtccc cgttgcccct cgaaccaatg gagaaaccgt agcggctatc
     6961 cttctggatt gcggtgcgac aattgcactg actgcgcaag ggggtaagga gtcttccggt
     7021 attgactggc tacaaacaga cgacaacgag cggcgtgctt cttttatgcg tttggctgac
     7081 gaaaataatc ctgcgttgct ccagtacacg tccggctcca cacgaacacc gcgaggcgtt
     7141 gctgtaaccc aggcgagcct tcgcacaacg atcgaagacc tcgaccgtgc agccctgcac
     7201 gatgctcaga gcgtgatggt gagctggttg ccgtacttcc atgacatggg cctggtgtac
     7261 ggcattctca cacccttgta ttgcggtttc agcgcttact tgatgcctcc ggagagtttc
     7321 attgcacagc ccttatcgtg gttgcgggcg atagcggctg tacgcggtac tcatacggca
     7381 gcccccaact ttgcctatgc cttgtgcgcg gatcgggctg ctgatctgct accaggaacc
     7441 gatctgtctt cgctacgatt cgcgctcaat ggtgcagagc cgattaggtg tgacagcgtc
     7501 cgtcgattcg aagcagcctt tgctcccttc ggaatgtcgt cctcagtggt catacctgga
     7561 tatggtttgg cagaggcgac cttgaaggtg acatccgggc gttgcggtga aggtacccgc
     7621 agtagacatt tcgaacctga tgcgctggcg gttgggaagg ttgttccctg ccaccaaggc
     7681 gttgagctgg cgtcatgcgg tactagctcg gtgggggcaa gcattttgat tgtcgaccct
     7741 gccactcttg ttccttgcaa accggatgtg atcggtgaaa tttgggttgc ggggcaaagt
     7801 gttgcggatg gttattggtc ccgtgagcac gaaacactgg agatattcca agcctgcctt
     7861 gctgctggag gaggcccatg gcttcgtacc ggtgatctcg gttttcttca gcaagacgag
     7921 ctctttgtcg tgggccgact gaaggatctg atcattgtcg gggggcgtaa tatctactgt
     7981 tacgacttgg aggactcggt ctctgaatgt cactcggata ttcgcaaagg ccgggtattc
     8041 gctgtcgctg tagaaggtga ggatggcgag gaggttctca tcggtgccga ggtgcgtagt
     8101 agctgcaaag agggtgatac acgggccatc cttgcgcgta tccgcactga gttaaagacc
     8161 cggcatgacg taggtgccgt gcgtatcgtg ttgcttaagc gagggagcat tcttcgcaca
     8221 tcaagtggta agacccgtcg tgcggcaaca cgcgatgctc tttttcgcgg tgagttgcaa
     8281 gtcatcgcag actccaatgg ccaatcagcc gaagttgacg acgacatcct tttgcaaatt
     8341 gctcgttttg tgccgggtgc tgtgagcgag cccaccagta ggctcattga tgctgggctc
     8401 gactcgcttt cagcggctcg gctggcagcg gccatttact cgcgttacgg tgtaaggctc
     8461 aagtttgaga cgttgtgcgc ggcatcggtc gatagtctgc gcagggacat tgccaatgca
     8521 caaagtgttg cggtcgcaga gtctttagct tcgtactcta tcgatttcac aaggccgttt
     8581 gaactgtccg aaatgcagca agcctattgg attggtcagc agagcggtgt tcccctgggc
     8641 agtgttcggc cacatattcg tgtcgatttt gaagtcgatc acgctcaggt accctctctg
     8701 agtctgaggc tggcggcgct tgtgacggct catccggctt tgcggatgtc cgtgcaagag
     8761 gatgggcgtg ggatcattga tcggcacggg tacgacccca ttatcggtca tagagacttg
     8821 cgcggtcttg cgcaacaaaa cctcgccgag gccttgagcg ctgtgcgtga cgaactcgct
     8881 caggacaatc gtcaggccct cagcgcttgc ttcacgcgcc ttactgatac caacacgctg
     8941 ttgcatttac gcttggggtt gctcgctggc gatttgcgaa gcgtgctgct ccttgttcgg
     9001 gaactagtca acggtccttc cctggcgccg ggtttctggg gcatggagag gcgcacttcg
     9061 cctatgccgc tagatgttcg cgaagcctgg ctgagaaagg tggcgtcaat cgcgccggcc
     9121 cccgatttac cgcaggcaat ggccgccagc gatgttgata ctccccgttt tgtcacgtgc
     9181 caccaggagc tatcgcaaga gctgacaacc gcgctggcat taaatgcgca ggcactagga
     9241 gtcacgctct cgtcaatctg catggcggca tttgttgatg tcttgcgttt atggtcaacc
     9301 tcgccagaac tgaccattaa tgtgacctgc agcacacgat caggtttgac cgaacaggcc
     9361 attggcgact ttacgagcag tatcctgctg tctttgtgcg agtcccacgg ctccttcgcc
     9421 gacttgtctc gggcaatcca gcaacaggta tggcgtgagc tggatgatcc ttgttccaca
     9481 ggtatttcga tgcttcgcga gctcagtcgc cgcaacggct caccggttct gatgccgata
     9541 gtcttgacca gccttctgtc gggagaccca gccgacgacc tctcggtcct tgattcaatc
     9601 gggcttatgg tcaacgtctc caatccgacc ccgcaagtat cactgcacaa catcctggcg
     9661 cgacgcgacg ggtgtttgat gatgatgtgg gagtacgtcg aacagttgtt tcctgccgga
     9721 atgatcgagg caatgttcgc atcgtttgtg gacgtgctca cgatgatcgc ccacacaccc
     9781 tctgcagtcg aataccccgt actggctaag cttccagccg ttcagcacgc tcggcactta
     9841 aaggcgaact cgacgaatcg cgacaggtcc ccgcgtcgat tgtctacgcc gtttatagag
     9901 cgcgccaccg aaaccccgga cgcgatcgcg gtgatattcg gtgatcaaat caccacctac
     9961 ggtgacttac tgcaggatgc cgaggacatc gccgctagat tgcaacgtaa aggcgtcagc
    10021 cgtggagata ttattgcggc cattgtcgaa ccaggtccca gggccgtggc agcactgatt
    10081 gggattggaa tcgctggagc ggtctatctc ccaattgagc cgtcttggcc gctgacgaga
    10141 attgaagagc tgttgtacga atccaaggcc gggtatgcgg tggtgatgca cagcatggac
    10201 ctgccgatac cgatgctgca gcttgatgag aaaccgggtc ggctccggcc tgagccggtg
    10261 ggtggtgcgc caagcgatgt ggcgtatgtg attttcacct ctggttcgac ggggcgcccc
    10321 aaaggcgtgg ttattaccca tgaggctgcg gcgaacacca tagacgacat caatgagcgc
    10381 ttctcggtcg gccctgcgga tcgagcattg tgtgtctcat cactggcgtt tgacctttct
    10441 gtctacgaca ttttcgggtt gcttgcggta ggcggcgcgg tggttttccc ggagcgattg
    10501 cgagatccgg acgcgattgc gcaagcattg acggctgctg gtgtaaccat ttggaactcg
    10561 gtacctgcag tccttgaatt gttgcttgat gtcgctgcgc ctcattcgtc cactttacga
    10621 ctcgtcttgc tcagtggcga ttggattgca ccggcgttta cggcgcgtat ccgtcaggtg
    10681 tttacccagg ccgagcccat cagcctgggg ggcgcaacag aggtttcgat ctggtcagtc
    10741 attcacccca ttgttcctgg cgacgcggca cgggtctcaa ttccatatgg cgcaccgctc
    10801 tcaaatcaac agtgttttgt gcgggcccct gacggacgtg agcgccctga tggcgtggct
    10861 ggagagttgc tgttgggtgg acgaggcctg gcccaggctt attgcggcaa cgatgcagaa
    10921 accaaccggc gctttttcac cgatcaggat ggcaatcggc tctatcggac tggcgatctt
    10981 gcacgatgga tggcgactgg cgaacttgaa ctgcttggac gtatggacga tcaagtcaag
    11041 gttcaagggt accgcatcga actgggtgaa attgaagctg tagcgatgaa agccggtggt
    11101 atttcacggg ctgtggcctc ggtcgttcga cgcaggggag cgacggtaat ccagcttcat
    11161 gtgcttgtgt cgcagggaat gcccggcgag gttgtgactt cagtgcgtgc ggcactggct
    11221 catcatctcc cggcctatat gcaaccgcat catgtggggg tactcgacac tctccctttg
    11281 acggcgaacg gcaaggtgga tcgctcacgg ttgccagcgc cacctgagcc gagggccgcc
    11341 ttgccgatgc gcggcgacgt tctgctcgaa acgatgatga tgcaggctta tgtcgaagtg
    11401 gtgggtattg gcattgatcc tcagcagcgg ttcttcgatg cgggagcgac ttcattgcac
    11461 atcgtgcgtt tgcgcgcact gctggagtct cgtgggatag cgattccgtc gctggctgac
    11521 ttcttctcgc ttgcgactat tcgatcaatt gccacctcct ccatggaggg tgtcagtgcc
    11581 aactccaatc agaacgatat tgcttgcatg cgcgcttaca agcaacgcct gcgagcgcgc
    11641 aggggagaat tgtaatggac caggatatac ctgttgatgc cgtagcaatc attggtgccg
    11701 gctgccgggt tccgggggca accacattgg aacagttctg gtcggttatc gccggcgcag
    11761 aggtgacgat tgagcgcttc agcgcggacg ttgcaaggcg cgagggggtg cccgagacgg
    11821 tattgtccca acccggtttt atcggggcgg gaggcgctct tgaaaatatt gagatgttcg
    11881 atgcggcgtt gtttgggatt gcgccttccc aagcagcctg tatggaccct caacaacgcg
    11941 tctttcttga atgcgttcat gacgcgctgg aacacgccgg gcacggtgcg gctcgaggtc
    12001 cacgcgtggg tatctgggca ggttctgcga gccttgatta tttggctgac catgtcttgg
    12061 gccagttgga tcgctcatcg ccgaaccgct atttgcaaca atgggtcggt gttgacaaag
    12121 attacctggc tgcacaagtg gcgtaccgca tggattttgg tggcccggca atcacggtac
    12181 agactgcctg ttccacttct ctggttgccg tcgcactcgc ggttcaagga ttgttgaatt
    12241 accaatgcga cgtcgccgtg gcgggaggtg tcagtattgg attaccgcaa cggcagggat
    12301 atgtgcatga ggacggtagt attctcgccg ccgatggtgc atgtcgcccc ttcactacac
    12361 aaagtagcgg cactgtgttt ggcaacggcg ctggtgcggt ggtcttgcgg cgcctggagg
    12421 atgcgcttga cgatggggac actattctgg cggtgattcg tggtgcagcg attaacaatg
    12481 atggggccgc caaagtaggt tttaccgcac ctggaggccg ggggcagggg gatgtgatcc
    12541 gcacagccct tcagctcggt gaagttgacg gggcttcgat cgggtatgtg gagacacatg
    12601 gtacagggac tgccattggg gatgcggtgg agctttcggc gttgatgagc gcattagggg
    12661 atcgacagct tgatgggcag cgttgtgcta ttggttcggt caaggcgaac gtcgggcata
    12721 tgaatgcagc ggcaggcgtg tgtggtttga tcaaagtcgc actcgccgtt cagcatgcgc
    12781 agattccgcc gacagtgggg gccgcgcacg ccatcgacgc gttacgtgaa ggatctcctt
    12841 attacctgcc aactgacctg acgccttgga gtagcccgga tcggcgggcg ggagtcagtt
    12901 cgttcggtat tggtggtacc aatgcccacg tgatcctgga agcatcacct cgtcgtctgg
    12961 cgcgggtgcg cagcaccgta cccctgctgc tggtttcggc gcgtgaagat gccttacgcg
    13021 atctgtgcgc aaactatgcg gcgttcttgg aggcggaccc agatctatct atcgaggatg
    13081 tgtgttttac ggcagctgtt ggaaggctac ccagggagcg gcgtgtggct tttcgcgctg
    13141 agcaccgtgg ccaactgatc agttcgttga aggcttttgc tgaaggcaga caagatgcga
    13201 acgcattttt ttacgaagag caggagcgtc gacctgaggt cacattcgcc tttggcgata
    13261 ccgataatct aggtgcggct atcgacggcg ctttagtctg gcaggcgcgc ggtgttgtac
    13321 cctcggttgt ctgcggtact ggagccggcc tgtttgcagc agcctttgcg gcaggtgcct
    13381 tgagcgctga ggatgcgcgc agtgctcagg cgcacaatgc ggtggcaccg tcactgcttt
    13441 ggatcagtgc attctcgggt atggcaattg atagcgtgga ggctgtgcgt aaggaacttg
    13501 cacaggtcgc gcagagtggg ggggatggtg cttcggcggt ggcggcaacc ggagcgacgc
    13561 gggtgcttga gttcggtgac aacgcgctag gtgctgatgt agctggtgtc gtttcattcg
    13621 cccagggggc gctcgatgcg attgcggggc tctggaccag cggtatcgat ctggatttga
    13681 cgaaaatcta cagcggcgca aatcgcgtgt cgcttccaac ctatccgttc cagcgtaagc
    13741 gtttctggat tgaccgcgcg ccccgttaca cagatagcgg cacttcaatt tttcttgggc
    13801 ggcgcacaga ggcgccaatg ctgcgagcca gcttctttga tgcccaatgg agcgtggcga
    13861 ccctgccatt tctcagtgat cacatgattt acggaaaggt catcgtctcc ggtgcggcgc
    13921 tggcggtgat gatcgctgaa ggggtgcgcg aggtgagtaa agcgcatgaa tttgctctgc
    13981 acgatctacg tttccccgct gccctggtga ttccgcaagg catggggcgt cgggtgcaac
    14041 tgcaacttgt acgtgatgat gatggttttg acgcgaccgt gttgacccag gatcccttcg
    14101 aaatccacgc cacggcccgg gtcgaaacga ccacaacggt cagtgtcgtg ccgtcgcagg
    14161 aggtgcaagg aatagacacc ccaaccgcct tgctggactc gtggttacgc gaccacggcg
    14221 tggtaatggg gccttcgttc agtcggctat cggacattgt catcggtcat aacgatgccg
    14281 tctgttcgat gcgcaccgat gctggcgatg acgggtggct gcttcaccca gggatcctcg
    14341 attcggccct gcaactcgtg gcggttgccg ctaggccgga agggagcaag gcgtttgttc
    14401 ccacccgtat cgctcggttg accatacgtg cccataccgc gtcgcaggtt cgttgctatg
    14461 ccgcggccga tcggggcctc gccacgctgt ttgacgacca cggcgttttg gccgaactgg
    14521 tgggcctgga gtcgcgtgat gtcagccgga acgaactgct gcgtatcgac ccgctgcgcg
    14581 atggctactc catcgaatgg cggagctcgt cgcttgatcg gtcgtttgaa ttgccacaga
    14641 ccgtcgtcgt tattcgggat gcggacgggg ttgccgagga gctggctgcg atcctgcagg
    14701 ctgagggcaa gcgtcccctt gttgtcggca gcccctctga tatttcgttt gagacaaccg
    14761 actttgttgt tgattgccgt gggtcagatg cacgttcgac ggcacccgac ctgagtgtgt
    14821 atgagggggc tttggacttg cttggtaccg tggcgagaaa ggacctcccg tgttgtgtag
    14881 ctatcgtcct gccggtgaat gtacccagtg gggcaccgct tcaggcactt gctcgggtgg
    14941 cggctatgga aactccctac cttcgcacct tggcggtacg cgccaacaat gcgcaaagca
    15001 ttcgtcgcgg cctcgacttt tttgatcaag aaacagaagt catggtcgat ggggataaca
    15061 tttcggcgcc gcgtttccag cgatttgatc ttccgcggcg tactgagtcg agtttttcgg
    15121 gcgacgaaac gtggctcatt accggtggcc ttggtgaact gggtttacgt gttgcgagct
    15181 ggctcagcgc gctcggggtt cggtcattgg tactcaccgg ccgacactca cctgatacga
    15241 atgcccagga aacactgact gtatttgggc atgaaggcat taacgttcaa gtgattcagg
    15301 ctgacttgtc aagcgaggca gacattgagg cgttgttgca caagatcgat acgacgatgc
    15361 cggctttgcg cgggatctgt cacttggccg gcgtggtcga ggatcgactc atgggcgatg
    15421 tcacacccgc atcgctgaaa acgacgtttg ccggtaaagc tgagggggca tggttgctgc
    15481 acgagcggac actgcattac ccactcaagc atttcatttt attctcatct gctgccgcgg
    15541 cgtttggtgc gccagggcag gcggcgtacg cgatggccaa tgcctatctg gatgagcttg
    15601 cagtctatcg ccggtcactg gggttgccgg cgctgtcgat cgcttggggt ccgtggcaag
    15661 acattggtat ggctgctcgt actgctgtca ccgcgaaacg ccggttgagt cagttgggta
    15721 tcggccagat agaggaggag tgcggtcgtg cgacgttcga gaacatcctg tttgccgatc
    15781 tgcccgcgca ctgcgtcctg cttgcggtcg attggcagcg tctggtcgga cagtggccgc
    15841 cccaggtgcc attcagtcgt tttgacgaca ttgtcagcga tattcctggc tctgcgagaa
    15901 cgttgtcggt caatgagttg ctcccactgt ctcccgatga acgacggcat cggttgttcc
    15961 agctgattgc cgaggatgtg tcatccatca cggggacaga cttggcgacg ctcgatccgg
    16021 aacgttcgtt gtttgagtac gatcttgact cgttgctcat tacagacctg cgtttgaagt
    16081 tcgagaggcg attcggtcgc ccggttgcgg caacggttat tttctctaac cctacggtcg
    16141 cggcgctggc cgaccatatg gcgcagacga tctttggtga ggtgccaact gacgtattgc
    16201 gcagcgtggc tgatcaagct ccgctgcctg tggcagtgct cactgagcca gacaattcaa
    16261 gacctgaaca gctatcccag gaagatgttg tcgaaatgct gtcggcgaag ctcgaagagc
    16321 ttcgtggagg gcgctcgtga tgagtatgag caatcccacc acgctgatgc acgatgcatt
    16381 gatagaaatt gaacggctcc agcgaaaact gggtgggctg gagcagcagt tgaaagagcc
    16441 cattgcggtg gccggcatgg cttgtcgatt tgccggtgcc gactcgccag aggcgttgtg
    16501 gcagttgctg ctggccggta cggacggtgt tcgtgcagtg cctgccgatc gatgggatag
    16561 cgagcgttac ttcgatgccg atccagatgc tgcagggcat atttattgcc gcacaggcag
    16621 ttttttagag gatatcgcgt cctttgatgc tggctttttc ggtatttcgc cgcgagaggc
    16681 gaccatgctt gatccgcaac aacgcatcct gctggaagtg gtgtgggaag cggtggaacg
    16741 ggccggtatt ccggcctcgg cgctgaaggg tacagccacc ggtgtgtttg tcggtgtgat
    16801 gcatcaagat tatgcccatc gcattcgcaa cgccgctgat gtggacttgt acagtgcttc
    16861 gggtaacgct gccagcgtgt tggccggacg gatatcccat gtgcttgggc tgcacgggcc
    16921 gtctatcacc cttgacacag cctgctcatc ttcgcttgtt gctgttcacc tcgcgtgtgc
    16981 tgcgttgcgc gccggagaat gcgacatcgc tatcgtcggt ggtgtgaacg tcgtcctttc
    17041 gcccatttcc actgcggcag agtgccgtgc tcatatgttg tcggccagtg gtcgatgccg
    17101 cccgttcgat gactcagcgg atggcttcgt ccgtggcgaa ggatgtggtg ttgttgtact
    17161 gcaacggctg agcgacgcga cggcggcggg acgctcgatc gatgccctga tcgcgggctc
    17221 tgcggtcaat catgatggcc gtagcgccgg gttgacggta ccgaatgaac acgctcagcg
    17281 cgaactgata cgaacggcat tacgggccgc caatattgat gcccggcagg tgcaatatgt
    17341 tgaagcccat gggacgggaa cctcattggg cgacccgatc gaagcagcag ccctggcatc
    17401 ggtttttgcc agtcgtgcga aagactcacc cgtacttctt ggttcgatta aaagcaattt
    17461 ggggcatctg gagggggccg caggaattgc tggattgatc aaagccattc tttgcgtaca
    17521 tcacggtgta gtacctgcca cgcttcacgt ccgtcagccg aatcgggggg ttgactggaa
    17581 ctcagtgccg cttcggcttg ctcggcagaa tgagccgatg agtggagccc agcgcgtggc
    17641 gggggtcagc tcctttggtt tcagcgggac caatgcccat gcacttgtga tggcggcacc
    17701 ggtctcccct gctgtacggg ggggcggcag ctttccacag ttattgaccg tctcggctaa
    17761 atcagccgca tcgcttctaa tgaatgcggt tcgctttgcc gagcacctct cacggattaa
    17821 cgaagccgag ctcgaagatg tttgccactc gtcccgtgta gcgcggacac actttcctca
    17881 ccgcctggcc gttgtcgcat cgagtgcgca ggagatggcc aacgagctac gccgatttgc
    17941 cttgggagag caggcgacag tggtatccgg tctggcccgt gcaatgtcac caagggatgc
    18001 cgttggggag gcaccgtacg aaacgcttga ggccattgct caaggttacg ttctgggcaa
    18061 gccggtcgac ttgaccaggc tggcgcctga gcgatgtcgc atagcgccac taccgaccta
    18121 tgcattcgac cggcaaaaat attggttgga cgagcggcta gggacagcac aagcacctgc
    18181 gctctatcgg atagcctgga gaccgatact ttcggttgca cctatacctc gttcaggcca
    18241 gcggatcatt gcaggggatg atccgcagtt gtgcggtgaa atcgcagcag cgttggaagc
    18301 tgcgggcgag caatgcaccg tagtgagggc tgaggccaag gctatccagg gggcaggaaa
    18361 tgccgacctg ggtgtcatgc tggtattcgc gagcattcag actgacgccg aaccgttgga
    18421 ggcaatcaca cgatatggcg cccttatcat cgagttggcc cgagcgctcg cgctgaatcc
    18481 atccctgggc cccgtggtga tggtgacaag aggcgcggcc tttaccgggc ctgcggagga
    18541 aattgatcct gtagccgctg ccatcaacgc agctgtgcgt gtcgcacgtc gtgagcaagg
    18601 gccgttatgg ggtaggtcga tcgacattga ccgctcaccc caatcacttg caacccttgc
    18661 ggcactgttg ggtggcgctg aagacgctga agaagacgtc gttattcgcg ccgccgccat
    18721 actcattcct cggttgcatc gtgccggtgc tggtgaggga atgcctgaca ttgccgctga
    18781 gggtgtttat gtcatcactg gcggtactgg cgccctcggt ctggccaccg cgcgttggct
    18841 ggtgcgcctg ggggcacgca accttttgtt gatcagtcgt cacggcgaac aggaacaaaa
    18901 cgtgcgcgcc agctgcgatc aattgcgcag cgagggtgtt gatgttcttg tggcctgtgc
    18961 cgatgttgcg gacgaagcat cactgcgtca tgcgttggca ctggtcgatc gtcccattcg
    19021 aggcattgtc cattgtgcgg gtgtgatcga cgattcgacg ctggtcacca tgacgccagc
    19081 agcatttgcc gaggtgttgc gtgccaaggt gggcgggggc catttgcttg accggctgac
    19141 aatgaaccag cccgtcgatc tttttcttct tttctcgtcg atttcggcgg cactcgggcg
    19201 ccatggccag gcggcatacg cagcggcaaa tgcctacctc gatgcacttt cgcagcaacg
    19261 ttgcctgcgc gggcgtcctg ccttatcagt cggttggggg ctgtgggccg caggcatggg
    19321 gacgactgac cccaaggtcc tggagcgcat gcgggccggc ggcctgctgg cactgaccga
    19381 aaccgaggcc tttggggcgc tggaaaaagc atttagcgcc gacgcacacc tcatcattgc
    19441 ggcgattgat accccgcgga tggcttcaca gccgaacctt ccgcgactgc ttgaggacat
    19501 ggtgggcggt caccccccga tgcgaagacc cgtgtttgat ttcgagcaac ttcgtgggca
    19561 caacgcggac gcccgccgag cactgatcac cgagtacctg gggagggaac tgcagttcat
    19621 cttgtccagc gatgtcgagt tgccgcacga cgtttcgctg attgaactgg ggatggactc
    19681 ccttaccggc tctgaactgc gcaacgccat agaacgatcg actggcattt atgtacctat
    19741 gcagcacttc atcgatggtt cgccgttgaa caccgccgtt gaagtgatcg tgggccaact
    19801 tgagcgccgg ctggtgacta ccttgccagg caggcagggc aatagcacag agaagatgac
    19861 cttatgacta tcgcacaact cttggccgac cttgcggatg tgggcgttac cctgcgtcgt
    19921 tgtggtgagc aacttgaagt ggagggccct accggtagtc tgggccccga tttgcttgag
    19981 cgtctgcgtc aatcgaaaca agcgctgttg caaatgatcc aggacgagaa cgccctgttg
    20041 acgaaaatgc cactgccagt tcccggcgaa ggcacagaag cctgcgagct ttcccttggc
    20101 caacaacggc tggtagtggc cacgcagctt ggagaaccta cgatctacaa cgagcaggcc
    20161 gcgattgagt tcgctgccga tgttgatgtg ctggcgatca ctgaagcttt tgcagcactg
    20221 gcgcacaaac acgacatcct gcacacggta tttactgacg atgagccctc acagcaaacc
    20281 gtgattgccg acgcgcgagt tccacttcaa tcctgggagg tgcgcagtaa cgacgaattg
    20341 cacacgttgg ctcggtctat cgctcaaata ccgtttgtca acggaaagct gctttggcgg
    20401 gttgatctct tctacaaagc cacaggctcg gtggtactcg ttctgacgat tcatcatgcc
    20461 atttttgatc gctggacgat gatgttgctc attcgagact tcagccaatt ccttcagcat
    20521 cccagtcatg tgaatgtagc ccaggctgca tcactgacgt atcgtgattt ttcagtctgg
    20581 caacgtcgct ggatggatac gcctgaatat gctgcgcaat tggattggtg gaaggacttg
    20641 ctgtcgggca tcgatagttt tccggtgatt cagggcgacc gtcctcctcc tgcggtgccg
    20701 agcgggcgcg gagctaccga acgcatgaag atccctgccg actgtatccg tgcggcgtca
    20761 gagttttcac gccagcaaaa caccacactg ttctccactc tgctcagtat ctttcagttg
    20821 ctgcaccacc gttataccgg tgagtctcag gtactgacgc tggcgcctgt tgccagcagg
    20881 ccctttcagg aagctgaaga gatagccggc tttttcgtta acttggttgc gatcgtaggg
    20941 cgtgtctaca aagacgatac gtttcattcg ttggttgagc gaacccgagg tatcactacc
    21001 caggcgtttt ctcaccagtt tgtaccgttc gatgcggtgg tagaacactt gcgccagacg
    21061 cgaggcccca gatctgacca actggcccat gtggtcttcg ccctgcaaaa cgtcaacctt
    21121 cccactgtcc gggttgaagg tgtagacgcg aaaccgttcg atcttgacag ccctttcgcg
    21181 cgtttcgatc tttacctgtc gattgaggga gatgagcgtg gcatgtttgc cgtatggcaa
    21241 tacagccagg atttgtttga tgcctctacg atacgcaaga tgggtgagca ttacgtctcg
    21301 ttgttacgtg gggtactcgc ggcccccgag gctcccttgc agtctctgcc catgtacagc
    21361 gacgtcgaat atgcacaatt gcaggcctgg agcaggcatg agcagcccta tcgcgctgat
    21421 gcaacggttg tggcgttgtt ccgggagcag gcggctgccc atccagagca aacagctttg
    21481 gagcagggaa ccgagtgttg gacctatgca caacttgagc gctggtctga ccgtgcggcg
    21541 gcagtgttac gcagcgccgg tgcgggtcgt ggttcgataa tcggtgtgac cggtgagcgt
    21601 tcgccgcgac tgattgcagc ctttctggct tgcttgaagg ccggtggcgc gtacttgccg
    21661 ctagagcgga actacccgga cgcgcggctg agcgaaatgg tggccgatgc cgagcctgcg
    21721 ctgatattgg tggccgatga cctggagcct ggctggctga gtagctaccc ggggccagtg
    21781 ttgaaactgt cggcctgcga ggccgaactc ccattccctt cgacgctgga atcgggtgcc
    21841 ggcgaccttg cgtatgtcat gtacacatcc ggttcgaccg gaaagcccaa gggtgtctgt
    21901 atcgagcatc gaggcatcgt gcgactggcc acaggggccg gcttcatgca gctggacact
    21961 tcgacggtca tgctgcaagc ctcatcactt gggttcgata cctcaacctt cgaaatttgg
    22021 ggctgcctgc ttaacggcgg tcgactcgta ctggttgagc aggggccgct gatacttgag
    22081 gcgatggccg acaccattgt aagcaaaggc gtgacctgtg cttggcttac agcggacctg
    22141 tttcgactca tggttgagga acaagtcgcc tccctgaggg ggctgcgcga attgctggca
    22201 gggggggatg cgttgccagt tgccagttgc aaggccttcc tcgaggcgtg ccccgacgtg
    22261 gcgttgatca atggttatgg ccctaccgag aacactacgt tcacgtctac gcatcgggtc
    22321 acccaggagg atgtacatcg ggtatcgatc cccatcggcc gaccattggg caacactcag
    22381 gtatgggtgg tgaacgagaa cggttgccct gtacctccgg gtgttccggg ggagttgtgg
    22441 accagtggtg atggtctggc gcgtggttat ctggggcggg aagacttgac tgtggagcgg
    22501 ttcgtccaag gaccattatt gggggggggg cgttggtatc ggaccgggga tcgggttcgc
    22561 tggcgccatg atggtgtttt ggagtttctg gggcgaatag acacgcaggt gaagctgcgc
    22621 gggtatcgca ttgagttggg cgagatcgaa atggtgctag gcgctcaccc gagcgtgagc
    22681 ggctgtgcaa tggcgctgaa ggaaaatgca gcaggtgaca agcagctcgt gggttatgtc
    22741 gttgcgcgtt ccggagccgc ggtgagtacg gcgcaggtac aggcatggct gggcgaacgc
    22801 ttgccagggt acatggtgcc gtctatttgg gtgtggctgc agacgctgcc gcaatcgccg
    22861 agcggcaaag tggaccgtaa acacctgccg ttacctgcct tcgagatagg ctccgtgaaa
    22921 gccagtaccg ccgctgaggc agcgctggtg aacatttggc aaagcctgct ggggttggca
    22981 caggttggag tacaggacaa tttctttgca ttgggaggcg actcgattct cgccatccag
    23041 atggcttcgc gtgcagccga acaggatgtg cgcatcactg cccaggatgt gttccgttac
    23101 ccgacgattg cccagctggc cgtcaatggt ggtttcggtg cagcacaagg ggtgcttgcc
    23161 gagcaaggcc ttgtagacgg tgaggtagcg ctcagtccga tccagaaatg gtatgtcgat
    23221 tggccgggag cggactggga gcagttcagc caaggggtct attttgatct gcatgcacaa
    23281 gtagatccgc agttattgag tgcgtcactg gcggcagtcg ccaggcatca tgatgtgttg
    23341 ggcattggct ggcgccatga cggtagcacc tggcaccagg aaagcggtgc aggggctgcg
    23401 gtggaggtgc tggttgagga tttgcgcggg caagcggacg ccttggcgtg cctggagcag
    23461 agtgctggag cactgcagca aagtctgagc ctgaatgctg cgagcgtatg ggcggctcga
    23521 atttaccggc tggatgaggg atggcgcctg gtatggctgg tgcatcacgt gtcggtggat
    23581 ggtgtttcat ggcgaatctt gctggaagat ctgctcagag cctatggcgc gctacagcga
    23641 ggggaggcgg tgagcctgcc ggcgaagacg gtgtcttacc aggcttggac gcaacacttg
    23701 gctacctggg gtaatcagtt accggcatcg cagttggcat actggcagcg tatggaaggg
    23761 tcaggaacgg atgtgccaat ggatggcgat gcgtcggtga gcgaggtggg cagcgaggcc
    23821 cgggtttcct tgcagttgga caggcttatg acgcaacagc tgctgcgtga ggcgggtgaa
    23881 cggtatcggg tacgtcctga agagctgctg gtggcggctc tggcgcgcac actctgtgcc
    23941 tggtctgcca gccaagagtg cgttgtggat atcgaaggtc acggtcgcga tggtgtggaa
    24001 ggcgtggacg tgggccgcac cgtgggttgg tttacaagcc tctatcccct gcgcctgacg
    24061 ctggagggtg ggttggcgaa tgacctgaaa gcggtgaagg agcggatgcg tggggtgccc
    24121 catggcgggc agagttacgg tgcattgcgt tatggccgtg aggacagtgg gttaggtcgg
    24181 catgagcgtt cggtgagttt caactacctg ggccaatggc gattggacga gctaggcacc
    24241 cccctggcgg gctggcgggg tcaggcaccc gggggatcgc gacggccaac catgcgcagg
    24301 cgccatgcgc ttgaagtcct ggcttatgtc caggagagcc agttgcatgt tgacttccag
    24361 tacagcgacc tgctgcatcg agccgaaacg atggccactc tggcgcattc ttttcaggtt
    24421 gaattgcagg cgctgctgac gcactgctta tcggtggaac gtggagggct gacgccctcg
    24481 gatctgccct tggctcatct tgatcagaat gaaatcgatg agattgagca tgatcatccc
    24541 cagttggcag acatgtacgg tgttacgcca ctgcaacagg gaatcctctt tcactctgtg
    24601 gcacagaacc ccagttttct gtatgtcgag cagctacatt ggcgaatagt cggtgagttc
    24661 agagccgatt gtttccaaca ggcttggagc gaggtcattc gtgcacatgc agcgctgcgt
    24721 acaacgtttc gttggcgaga cctgaagaca ccagtccagt tggtccatca tttactggaa
    24781 cctgattggg gcactctgga ttggcgtgaa ctgtccgctg agacctgtcg cacgcgtttc
    24841 gaaaacctgt tgaacacgga ccgtgagcgc ggctttgact tggaacacgg gccattgcta
    24901 cgaggcacct tgattcgtga gcaagagagt tcctggcgtt tcctgtggac ctaccatcat
    24961 gtggtgtttg atgggtggtc ggtggcgttg attctcaagc aggtgctcaa tcgctatgcc
    25021 ggtttgaatg ccggcgcaga gattctcccg agcagtttac ggccatttgt aagctggctg
    25081 tccgggcgtg atcaggagga catgtctgtt tattggcagg aggtgttggg gggcattgtc
    25141 gaacccacgc tgacaggttt tgagtcccca gcccataatc gacaggctct tgctcgggat
    25201 cgttgtgcat ttcgcgtgga tgacgcgttg tgtgatgcgc tgggactggc cgccagacag
    25261 gccgggatca cccaggccag tgtgctgacc ggtgcctggg ccttgacctt gggcctggcc
    25321 ggcggtggtt cggatgtact ctttggcacc acgttatccg gtcggccagc tgacctgcag
    25381 caagtagagc tcacagtggg gctgttcatc aatacagttc ccgtccgcgt gcgcattgat
    25441 gacgacgacg tcgtttctga ctggttacag cgtttgcacc gtcagcaaag cgagcgtgag
    25501 aaatactcca cggcatcact gacgacggtt caacgctggg caggtctgaa cggtggggat
    25561 ctgctgagca gtctgttcgt tgtagagaac tatccgattg actcgatgct aaagcaatcc
    25621 gatatcggcg tggacattac cgagctgact tccattggcc ataccaactt tcctttgact
    25681 gcccaatggg ttccaggcga agaaacggtt ctgcatgtga tttttgatac ctcgcgttat
    25741 gacgaggtct cgattcgccg actgggtgac agttttttac gggtactcag gcaacttgtg
    25801 ctgcaaccgc agtccaggat cggtgagatt tcgttggtga gcgaggctca aacacaacaa
    25861 ctcatttacg attggaacga tacccctgcg accagtgacg gttttttgct tcatgagggg
    25921 atcaagcggt atgcggcgct gacgcccaag gctgcggcag ttatcggcgt aagtgaccgg
    25981 atgagctatg acgagctcgc ggcgcagcag gaacgtatcg ccacatcggt ggtagcagcc
    26041 aatgcacgat ccgagccggt cgcggtgttt ctgccacgct cgttgcacgc tgttgcagcc
    26101 tatgcgggcg tgatgctggc aggttgcgca tacgttccgg tcgaccctgc gacgccgccg
    26161 cgccgcttgc aggaaatctt cagcaccatt ggctttgtgg tcactacgcg agcactcgct
    26221 cctcagttcg acgccatcgc ggtgcaaacg atcctggtcg acgaggttgt atcagcgcaa
    26281 ctgcccgacg tcgcaatcaa taacttggcc tatgtcatgt ttacctccgg ctccacaggg
    26341 aaacccaagg gggtaatgat tgatcatcgc gcggcttccc tgacgatcga atccataatt
    26401 gagcgttatg ccatcggtac gagggatcgc cttctttgcg tttcttccgc agggttcgat
    26461 ctttcggtgt tcgacttctt tggtgcattc gccgtgggtg cagccgtagt gctggcacct
    26521 gagtcgacta ccgttgaccc tggcacctgg ctagatctaa tggaacgaga gcaagtgacc
    26581 gtctgggagt ctgtgcccgc ggttatggag ctcttattgg cagaatgtcg tcagagtggg
    26641 cgcaaactgt cgtcctcgtt aagacttgtg atgttgagcg gcgaccgggt tgcccttggg
    26701 ctgcctgagc gtattcgtga ggcggcaacc agcgagctgg acatcattgc tctcggtggc
    26761 gcgacggagg cagctatctg gtcgtgttat tacgacacaa aagaactggc tccgggcgcg
    26821 cacgtcattc cttacggtcg ccatctcccg ggccagcgac tctatgtgct gtccccggcc
    26881 ctacgccctt tgcccattgg tgttccaggc gatctttgga ttgctggtgc gggggttgca
    26941 cgcggctatc tcggtcagcc ggagctgacg tccgagcgat ttatggccga cccgtatgtt
    27001 cccggccaaa gcatgtataa gaccggagac cgtgcccttg tcctggcaga cggcaaccac
    27061 gaatttctcg gtcgggtgga tgaccagatc aagatcggcg gtttgcggat cgagcttggt
    27121 gagatcgagg cggcccttat gcaggcccct ggtgtcgagc gtggagttgt ctccatcgtc
    27181 gagcacgacg gacgacggat gatcgcagcc tatgttcttc ctcacgccgc cgaggctttc
    27241 gatacggtgg ctgttggcga atcactgcgc caggcactgc cagcctacat gttacctgcg
    27301 tcaatcatga cgcttgaatc tgtgcccttg accgcaaacg gcaaagtgga ccgtaaacgc
    27361 ctgccgttac ctgccttcga gataggctcc gtgaaagcca gtaccgccgc tgaggcagtg
    27421 ctggtgaaca tttggcaaag cctgctgggt ttggcacagg ttggagtaca ggacaatttc
    27481 tttgcattgg gaggcgactc gattctcgcc atccagatgg cttcgcgtgc agccgaacag
    27541 gatgtgcgca tcactgccca ggatgtgttc cgttacccga cgattgccca gctggccgtc
    27601 aatggtggtt tcggtgcagc acaaggggtg cttgccgagc aaggccttgt agacggtgag
    27661 gtagcgctca gtccgatcca gaaatggtat gtcgattggc cgggagcgga ctgggagcag
    27721 ttcagccaag gggtctattt tgatctgcat gcacaagtag atccgcagtt attgagtgcg
    27781 tcactggcgg cagtcgccag gcatcatgat gtgttgggca ttggctggcg ccatgacggt
    27841 agcacctggc accaggaaag cggtgcaggg gctgcggtgg aggtgctggt tgaggatttg
    27901 cgcgggcaag cggacgcctt ggcgtgcctg gagcagagtg ctggagcact gcagcaaagt
    27961 ctgagcctga atgctgcgag cgtatgggcg gctcgaattt accggctgga tgagggatgg
    28021 cgcctggtat ggctggtgca tcacgtgtcg gtggatggtg tttcatggcg aatcttgctg
    28081 gaagatctgc tcagagccta tggcgcgcta cagcgagggg aggcggtgag cctgccggcg
    28141 aagacggtgt cttaccaggc ttggacgcaa cacttggcta cctggggtaa tcagttaccg
    28201 gcatcgcagt tggcatactg gcagcgtatg gaagggtcag gaacggatgt gccaatggat
    28261 ggcgatgcgt cggtgagcga ggtgggcagc gaggcccggg tttccttgca gttggacagg
    28321 cttatgacgc aacagctgct gcgtgaggcg ggtgaacggt atcgggtacg tcctgaagag
    28381 ctgctggtgg cggctctggc gcgcacactc tgtgcctggt ctgccagcca agagtgcgtt
    28441 gtggatatcg aaggtcacgg tcgcgatggt gtggaaggcg tggacgtggg ccgcaccgtg
    28501 ggttggttta caagcctcta tcccctgcgc ctgacgctgg agggtgggtt ggcgaatgac
    28561 ctgaaagcgg tgaaggagcg gatgcgtggg gtgccccatg gcgggcagag ttacggtgca
    28621 ttgcgttatg gccgtgagga cagtgggtta ggtcggcatg agcgttcggt gagtttcaac
    28681 tacctgggcc aatggcgatt ggacgagcta ggcacccccc tggcgggctg gcggggtcag
    28741 gcacccgggg gatcgcgacg gccaaccatg cgcaggcgcc atgcgcttga agtcctggct
    28801 tatgtccagg agagccagtt gcatgttgac ttccagtaca gcgacctgct gcatcgagcc
    28861 gaaacgatgg ccactctggc gcattctttt caggttgagt tgcaggcgct gctgacgcac
    28921 tgcttatcgg tgaatgaggg ggtcactgca ctcgtcgcac agctgaataa tgtcgaggcg
    28981 gtttatgggc tgacgccgat gcaggaaggc atgctttacc acgcgcttgc cagagacgga
    29041 atgtacgtcg aacagttggc ctgcacgctg acaggtattt tggatgaaca ggctttgcag
    29101 gacgcatgga atgatgtggt ggcgtccaat ccagtgttgc gtacatcgtt tcattgggag
    29161 ggtttggcaa ggcctgtgca agtagtacac caggttgcac aagtaccttg ggtgctggag
    29221 tcgtgggcag aagggctgga catggacgcc tggctgcggg cagaccggcg caaggggctg
    29281 gacctgcgga ctgcaccttg cttgcgatgc gcactgctac acacggggcc gcaacgctac
    29341 gaatgggttg tgacctacag ccacttgctg ctggatgggt ggtcgttgtc gctgatgatt
    29401 gaggcgctcg cgcaggccta tgcggcgcaa acagcagggc aaccttatca gccgccagtg
    29461 cgtagcccat tcattgatta cgtgagctgg tcacaggcga cattggatca gggtgtgggt
    29521 gagcatttct ggcactccca gctctacggt ttcgagggtg tccgttcact atcgttgccg
    29581 gttccggacg tgaccgaagc gtacgcagaa cctgtattga tcaatgttca gcggtctttg
    29641 gtcgcaaccc tggaaaaaca acaacgagtc accctggcga cagtcgtggc gggttgctgg
    29701 gcagtactgt tgagccgtta tggagaaggc gacgacgtct tgtttggcat gaccagtgcg
    29761 gggcggcggg cgcagataga gggcagcgag tccatgatgg ggctgctgat cgaaacccgg
    29821 ccgacgcgca ttgaggtaga cgagcaggca cctttggggg attggttacg gacgatcatg
    29881 caggaggagg caaagcgcga agaagcgggt gcagtctctt tggctcagat tgagagctgg
    29941 ggaggggcgg aacgtggagc acgattgttc gacacgctgg tggtggtaga aaaccagccg
    30001 atggcgatga tcggtgacct gctaggaagt caggtggtgg tggcgaatgt gcgcaccgtg
    30061 gagtgcacga actggcccct gacagtggtg gtattgccag aacaagaaca gctacggcta
    30121 gtgttcctgt acgaccccga acattatgcc cggcaggcga ttgagcaagt cgccaggcat
    30181 ttttcgacgt tgttggcgtc tgcgggtgaa gccgtccagg tggccgacct gcagatgctg
    30241 gacgaggctg agcgtgaaat gttggttgaa cgctggagcg gtgccgatca ggtacacgca
    30301 gcttctaacc ggaccatcgt ggagcgcatt gaggagcagg cgactctacg tcctgatgct
    30361 attgcgttgc ggttaggcga gcgaagcatg agctacgccg agttgacgac gagagggcgt
    30421 cgtgttgccg cttggctcca gcgccaggac gtgggtgtgg gtgggcgtgt agccattgtc
    30481 ggcgagcgga caatggaaac catagccgcg atgtacggga tcctgttgag tggtgcggcc
    30541 tacgtcccgc tggacccgga ttggccagag gagcgtaagc gcctggtgat cgaggatgca
    30601 caaccccagg tgttcattgg ctcgacacat atggcatgtg ggtcgtcgct acagatatcg
    30661 ctggagaccc tcgaagggtt taccgatgag cgattgacag ggcggtcggc tacgccgcaa
    30721 gacctggcgt atgtgatttt cacatcgggc tcgaccggaa gacccaaggg ggtaatggtt
    30781 cggcacgcag acgtgatgca cctggacgga ttgcaggacg ccatggcgct gagtgacgcg
    30841 gatgtatgga cctcattcca ctcgtatgcc tttgacttct ctgttctgga aatatggtat
    30901 ccgttgatgt ggggtgcaac ggtggtcccg gtgccgtatt gggtcagccg tgagcctgag
    30961 gcgttcctgg cgctgatctg cgccgagaag gtcacgatca tttgtcagac acccgcggct
    31021 tttgaacagt tgatctccac ggcccggccg ggttgccggg ccggtcatgt gcgctgggtg
    31081 ctacttggcg gggatcggta cagcgcggcg ttgtttgcag ctggcgatcc cgccgaattt
    31141 ccgaacatcg ctaacgtata tggcatcacc gaaacgactg tgataaccac ttttgagccg
    31201 ctggaacgtg accgaccggt agctatcggt cggccatttc caggccagcg gatctatctg
    31261 cttgaccgga agaagcggtt ggtaccaccg ggggccgtgg gcgagatgta catttgcggc
    31321 gaaggtgtcg ccgcagggta tatgggcgca gaggcgctga cggcccagcg cttcagcgat
    31381 gacccctatc aacccggcgc gcggatgtac cgttcaggtg atcttgcacg gtttttgcca
    31441 ggcggacgcc tcgagtcgat tggtcgggca gaccaccaag tcaagatccg tggctaccgg
    31501 atcgaactgg gcgaagtcga gagtgcactg tcatcgcttg ccgtcgtgaa cggggcgatt
    31561 gtcgacgtcc gcaatgggcc caatggccgt caacttgtcg cttggtatgt ggctgccgaa
    31621 agtgtcagtg cgctggatgt tcgtgctgcc ttgaagtctc tgctgcctga aagcgctata
    31681 ccgtcggcac tgattcgtgt cgatgcattt ccattgacac ccaatggcaa ggtagaccga
    31741 aaggctcttc ctctcgagga cgccgtgtca ttaccgtcaa taaggccgag cagtcataac
    31801 gaaatggcta tcgaggccat ctggtgcgaa gtgctgggcc aagaggcaat tggggttcat
    31861 acgaacttct tcgacgccgg tggcgactca atcgcaatcg tgcgggtgca cggattaatg
    31921 gccgtgttac cgggtgctga acggctgcgt gtcgtggatc tcttccagtg tcccaccatt
    31981 gctgcgatcg ccgaaaaaat cacgtccagc gaagcacaga cggcagtagg cgatgactcg
    32041 tctgcacgcg gcgtgcgccg ccgccaggcc ctcgagcgcc accaaaacgc aaggagcaag
    32101 ccacaatgaa tacgtcgaac gctatcgcga tcatcggtat gggctgccgg ttccccggag
    32161 cgtcatccct ggagcagttc tggacgaatc tggtaaacgg tgttgagtcg atcacctcct
    32221 tcggcccaac caggcaccat gaagcctggc aggaggtttc ttctgcgggc attgtggaca
    32281 acgcctcatt gtttgacgct gcattgttcg gtctcagtgc gcgcgaggct gagcggatgg
    32341 acccccaaca tcgggtcttc cttgagtgtg cctgggaagc gctggagcgc tcaggctatt
    32401 acccaaaaca gctgccaggg cgggtagggg tttttgcagg cacgggcttc aatgagtact
    32461 tggtacgcaa catcatgccc ttggcgccgg agggtgatct gtcgttgtta ttgacgaatg
    32521 acgcctgttt cctgtcttca cgcctggcct atcttctggg atgctcaggc ccggcaattg
    32581 cagtctcaag tgcatgctcg acgtcactcg ttgccgtcca tcttgccgtc cagtcactgc
    32641 tgatgggtga atgtgataca gcaatctgcg gtggtgtgcg tatcaccaca ccacagaacc
    32701 gaccctaccg tcacgaaccg ggcggtatcg gctcatcgga cggtcattgc agggccttcg
    32761 acagtgccgc caacggtact gtcagtggca atggggcggg tgtggtggtg ttgcgccgtc
    32821 tcgacgatgc gcgcaacgac ggtgatccta ttgcggctgt tattctcggg agcgccgtta
    32881 ccaacgatgg ggcacaacgt gtcggtttca ccgcgcctgg cgttaatgga cagtgcgctg
    32941 ccatttgcga agcacaggcc ttggctgatg tttctcctga ctcgatcggt atgctcgagg
    33001 ctcacggtac tgcaacgacc ctgggcgacc cggtggagtt tgaagcgctg agcgcggctt
    33061 tccgacatgg cactacacgc cgcggtttct gcgccttggg gtcggtcaaa accaacattg
    33121 gtcatcttga tgcagcggcg ggcatcgctg gactgatcaa aacggtgctt gccttgcagc
    33181 atcgggttat tcctgcgtcg cttcactttc gcgagcccgg ttccggcatc aacttgcagg
    33241 aatcaccgtt tttcgtcacc gccactgcgc gcccttggct cgaggcaaca cggcgtgctg
    33301 gcgtcagttc gttcggcatg ggggggacaa acgcgcacat cgttctggaa tccgcgcctg
    33361 aaccattggg cgatacttgc gagacggctg aaccgcagtt gcttgaactg tcggctcggt
    33421 cagaggcctc gctgcatcag atggcacagc agcttgctga tcatcttgag cgtgaacagc
    33481 cactgctggc cgatgtggcc tatacgcttg ctgtctcacg taatgcctat gagtggaaaa
    33541 cctcagtaga gtgcacatcg cttgcagaag cggcggaggc actcaggggt ccgcttcaga
    33601 tcacacggtc atcctgtgca gcacagatcc cgcgagcatc cagacgccgg atccacctgc
    33661 ctgcaacgcc cttcgagcac aaacattact gggtcgaccc accttcgtcc tttgcataca
    33721 gggcgaatcc ggctgactgg ctctacactc cgcgtcttcg acagagtatg ccgttggagc
    33781 aactacttat cgacagccag cgtaattggc tggtgctcct ggatgatcat ggggtcgggc
    33841 aacgtattgc tgccgctctg cgtgacgcgg gggcacagac agtcgttgag ctggtgtata
    33901 ccgacgatac cgtatcggat gtgatccata cgcaggtcga ggctgattgg agtcgtcctc
    33961 tctcggttat ttccttatgg agtctggcag cccaagacag cagcgatgac cgtgaggtgc
    34021 tgcaacggca ctacctcagg ccagcacagg tgttgcgagc ttgggcagac aaagctggcg
    34081 gcgatgttga cgtgaccttt gttgtcaatg gcgctttcga tggattcggg tcacccactg
    34141 cgccagaaaa agcgatgttg ctggggctgg cgcgcgcatt gcggctcgaa tatcccagtt
    34201 ggctagcgag ggtcatggat gttgagatgc tcgcgcagga caccgtcgaa tgtatcctcg
    34261 ctgaggccac tgcgtgctcc gctgacgatg cggtcattca taaataccgg tcacgctggg
    34321 ttgaaaccgt tgagcccgtc acgatttcgg gagggcatac actccctatt cgacgtgggg
    34381 gtgtttatct ggttacaggc ggtaacagcg gaatcgggtt ggcaatcagc agatacctga
    34441 tcgacagctg gggtgcgcat gttatcgcgc tgagtcgtcg tggtggtcag tctggccaag
    34501 gattcactgc cgttgcggcc aacctcgaca atatcgacga gttacggcaa gtggtggtca
    34561 gtattcaagc cgagcatggc cccatcaatg gccttgtgca ttgcgctggc atgccaccgc
    34621 acgccttgct gcgaaccgcg acggatgcag cagtcaagga ggtttttgca gggaagtttt
    34681 ttggagcgct caatttacag cgcgtgatgc tccagatgcc tctggatttt gtggtgctca
    34741 gttcctcgtt acgcgcccat attcctgcag caggatcggg agattacatg gcggcgaatc
    34801 tggcgctgga agcactggcg acgtcatggg ctgcaaccgg agcacgcgtg ctctccatcg
    34861 cctgggacac ctggagcaaa gtgggaatgg ccgcaacggc ttccgatgcg cgcttcgtta
    34921 cggatgaact tgacgctgag gggatgagcg ttgaagaggg ggttaagctc ttcgaggcgg
    34981 catcccaatg cggtttgtcg cgcgtagtcg ttagcacacg gccgttttcg gccctgaaag
    35041 cccatgccca agaggcattt tcagtggggc gggcgggcga ggttgcgcaa cgggtaagtt
    35101 ccacccggca tccacgacct gcacttaata cagtttatat accggcccgc accgcactcg
    35161 aaagccagtt ggcgcaaatt tggtccgaaa tccttggtta tgacaccatc ggaatcaagg
    35221 atgatttttt cgatttgggc ggcgactctg ttgcgacgct gcaaattgtt gctcgcgccc
    35281 gagagcaggg gttgaacctg gaaaccagcc gggcatttga ggcgcacact attgaagagt
    35341 ttgccgctgc cactcgtatt gagctggctg aggagctcct tctcggcgac acgccgttgc
    35401 cactttctgc ggcacagcaa tggttgtttg cttgcgagtc gggggatatt aaccgattcg
    35461 tccaaggggt cgtcatcaac ctgcccgagg gtaccgacgt gctatcggtg ggtgccgcaa
    35521 ttgatgctgc cgtggcgcat cgtcgggtgc tttcggttcg gtttgcgcaa accgagtcgg
    35581 gttggaagca gcttctgggc gcgtcgcaat ccgtagctgt cgaggttcat caatacgttg
    35641 ggtcgcccgc aggacaactg gatcatgcga ttgaaatggg tgggactctg cagcgctcaa
    35701 tggacatcca ggcgccgcta ctggtacgtg ccgcgattgt gtccagccct gtcgaatcgc
    35761 acttggtgat cgtcgtccac catctactga tcgatgcctc tggttggcga atactcctgg
    35821 atgatatttg cgcacgcgtt gcagaccttg gccgagctac cgacgtaccg gatgaagcct
    35881 ttctgcaatg ggttatccat cttgatggta tcgcacagga cgcgaagatc aacgaggagg
    35941 aggcagccta ttgggcatcc ctcgatcttc cggaccagga ttttcctgca ttgcgacgta
    36001 agggatcgac aggttccttg acctcgacgc tttcagtggc gcaaacacgg gttttgacct
    36061 caagtcgcaa atctatcgaa gcgctgcttg ctacggctgt cgcctatgct ttacgtcccg
    36121 ttgctatgtc agaccgaatc ttgattgaca ttgagtcatt ggggcgcggt tggtcccgcg
    36181 tcccacagga tgtctcccgg gcaatgggtt ggttcaccgc tatccatcca ctggtcatag
    36241 atacggctca gggcatttac gctgcggcag cgcaagccgc aacacttgta ccacaagcgc
    36301 gccaccgtgc tgtggcgtac accatgttgc gccagcatgc gccggaccta ctgccgcccg
    36361 tgttgcgaag tgatgctccg gtttcggttg tcttcttccc ggcccccact accgtgcctg
    36421 gctggtcgat cgcctctatc ctacctccac cagaggggat gccggcgcca cacgcagttg
    36481 cactcgcagc aaccattgaa aatggagcac tcactttgca atggcacggg cagacagatc
    36541 cgttcgaagg tatggcgctt gccacccttg tgtcgcgaac aatgcaggga cttcgggaac
    36601 tggtggcggg tggaaaggac cagatgagtg cgcttatgac tcagcttgac atgtcagggg
    36661 tggatgatga atgaccgagt tgcggcattt tcggcggttg aagcggcact ggctgcaccg
    36721 gaggcagcat tggcgggcgg tgactttgct acggtcgagc agttaatgag tgacatccgt
    36781 ggggcaaacc gggcgagggg gctttggctt cctcagctgt cacgagtcaa tggtggttca
    36841 gggctcgacc tgctcgaact ggtcgaggtt ggagaagtcc ttggcaggtc gccactgggc
    36901 cattatgcgg ttaactatca ggcacctgat gccggtaata tcgacatcct tcttgagtac
    36961 gcaacgtctg agcagaaaag gcgttggctt gatcctttac tgcagggcaa ggttcgcagc
    37021 tgttttgcgg caaccgagcc ggacagggcc ggttccaatc cctctgctct ggcgaccaag
    37081 gctgtgttca aggagggagc atggcatctc acgggccgta agtggttcgc ctcgggtgcg
    37141 gaccgtgcgg catttgcgat cgtgctcgcc gttaccgatg agaccgcgcc actgcacgcg
    37201 cgaaccagta cttttatcgt accgactgac gcacccgggt atcggcatgt tcgtaacatt
    37261 cgcgtgatgg gcgacgaggg atgcggctgg gcgagccatg gtgaaatcga gctggacgac
    37321 tgtcgggttg agacagacgc gttgttggga gagccagggg ctgggttcgt cgtcctgcag
    37381 tcccgccttg ccacgggacg gctacatcat tgcgcgcgct ggattggtgt ttgcgagcgt
    37441 gcgttcgcca ttatgtgtcg acgggccagc cgtcgcgagc ttgcaccggg ggagtttttg
    37501 tcgtcgcgcc agacggtaca gaactggatt gctgaaagcc gtgcgtcgat cgacgcggcc
    37561 cggctccttg tcgctcaggc cgcgtcgcgc ttgcagaagc gccatgagcg agcccaggtt
    37621 gacatatcaa tagcgaaatt ttttgtcgcc ggagtcactc agaccgtcct tgatcacgcc
    37681 ctgcagatcc agggtgcact cggtgtcagc ggtgacacga tcgtaaacgt cttctggcgc
    37741 catgagcgcg caggacgcat ttatgacggc cccgatgaag tacacaaggc gctggtcgcg
    37801 cggcacgcgc tggccgcgtt tcgtggtgag cctcgatgag cctgcaggtt gcacacagca
    37861 cgatgacggc tctggggagt cccggtgcag ccgcactggc gacccgtatc ggagcaggtc
    37921 gatccagtga gacatacctg gtgcaggcga acgatcgcga cctcatcact tatgttttgc
    37981 catctggcag tgcgcgggaa gcgcaacgtc gtttcgcagt cttggcgcag attgctgagc
    38041 gctatcgtct agcacccaag ccgcttgctg tggtagaggc ctgcgacgag ggtcggacat
    38101 tactggtgat ggagcggctc ccaggggttt tgccgacggc ctgtggctct ctttcacctg
    38161 atatggttcg tcgtctctgc gccggcttta tttctgcgct ggcgtcattg catgctattg
    38221 agattgctcc tgttgatcgg cctccggatt atctgcgtcg aagtattggt gattgggagc
    38281 ggcgatggtg cgaagaagag gcggcaggtg ctcacgatga cttcaaatcc gtggtgcggt
    38341 ggttggcgga taatctgccg gaccaggttg cgtcagcttt tgtgcacaat gattttaagc
    38401 tggacaacat tctggtcgat cccggcgacc ccgcacgggt ggttggggtc gtggactggg
    38461 agttggccac cattggccat ccccttgccg atttaggagt cgctctggct tattggattg
    38521 aacgtcgtga ctcttcgttg ttgcgtcttg aagcgccagg gccaagctgc gctttagggg
    38581 cgccgacccg tcaggaactg gttgaactgt actctgcggc cagcggtcgc gaagtgctgc
    38641 atgcctcgta ttggtatgtc tacggattac tgcgtctggc ggttatcacc cagcaattgg
    38701 tattgcgtca taaagacggt ggccaatccg ttccacgtgg tttgctaatc gtacgatcgc
    38761 tcttggcgca tgcatcgaac acttgtggga gcggacgact atgaaagcaa acattcagga
    38821 catccacggc ctcgcaccct cgcagcacgg aatgctgctt gaaagcacta atggcttgac
    38881 ccagggcgat atgttcatag agcaaagcgt tctgttggtt cgcgggaaac ttgatacccc
    38941 gcgttttctt tcggctgtcg agcagatcgc aaccatccat agcagtttgc gcagttgttt
    39001 tgcatgggag ggcgagaccc ctttgcacgt tgtgttcgat aaggttcggc ctgtcgtgga
    39061 gtgggaagat tggcagagta aagaaggtgc agatgatcgg caaacgctgg aagcgtggct
    39121 ggcggcagac cgttcacgag gtcttgccgt taatcgtgca cccctgtggc ggttcacggt
    39181 cattcgttgc gccgaggagg tgcaccgggt catttggacc catcaccacc tgattacaga
    39241 tggatggtca attgcagtgg ttctcaacga tttgctcgac cactataagg gtctccatcc
    39301 tgtgcctgcg gctcgaccgt tgcgtgatta cattgattgg gtagaagcac aggacagagg
    39361 gcaggctatt gctttttggc gccagcgcgt tcagcgcttg cctcggttgc cacctatgcc
    39421 accacgggcc catgagcact gcttcgtgga gattgacggc attgatgtga gggggattct
    39481 cgatacggcg cgcaagcaaa aggttgcatt cgcgacggtg gcatttgccg catgggcact
    39541 tgttttgcga gcctctcggt ccagcgacga agtcgttttt ggcatcaccg tgcatggtcg
    39601 cccggcagaa attgtgggcg ttgaacgaat ggtcggaccg ttcattgcga cattccccat
    39661 gtacttgcag atggcacaca tgagtacaac cgaggaactg ctgcaccaga ttgaacagca
    39721 acagagtgaa cagcggcctt ttgaatacct atcggcagcc gaggtccacc aggcgggagg
    39781 tatcgccact cggctctatg acagcctggt ggtggttgaa caaattcctc aacacagcgc
    39841 aatggccact gggggaatat cggtttctgc cgaatccgga aatggcgcgc gctcgcacca
    39901 tcctttgttg ttacggttct cccaggatgg gatggctcgc ctcatgtaca acaagaagtt
    39961 cttcgatgac gaaaccgcaa gcggactggt gtctttgttg cgtcaagcag cggtacggct
    40021 ggcctcgaac gacggtctgg tgagccttga tggcgcgatg gcgttttacg ccccgataaa
    40081 gcccaggcct gtgcgcatgc ctcgaaacca ggaggagcac atcgtgcttt ctcttgcgcg
    40141 tactcttttc ggtgagcacg ccacccttga tgacaacttc attgatctgg gcgggcattc
    40201 gttactcgcc gtgcaattta ttcaacgtat cgcccatgag acaggggtgc aattacccat
    40261 tacacagttc ttgcaggatg atcgcctcag ctcgctggcg aaggcattgg gggacagcca
    40321 ggctggtgtt gtggacgtct ctcaccccag gatcttattt gtcccgggta atcctggaac
    40381 tgtcctttat gcgtctcgat tgtccgtgca cctggtggat tggcgtttac atggtcttga
    40441 ggcgccaggg ctcgatggct cacagccgcc gctcgcaacg gtcgaggcat tagccgagca
    40501 tcaccttgca agcctttcgg tggacgataa ccccacagtg atcatcgggc attcctttgg
    40561 tggatgggtg gctttcgaga tggggctacg gttacaggcg cgtggccgtg aggccgtggt
    40621 gattctgcta gacactgtct ccccctatcg attgctttcc cgaggcgatg tctccgacga
    40681 ggggctacgg gcggaagtcg agcatttgaa gatccgtgcc gggagtgctg gtattaacgc
    40741 gcacatcacg ccggctgtat ttgaagttta tgttgccgcc cggcgcgcga tctatgcacc
    40801 tgccgagcaa gccaggttcc caatgatgtt gtttcgggct tcccagactc ggcctgagga
    40861 cacctgggat aaaaccgccc ccgactatgg ttggggcgaa ctctgccagc agctccatgt
    40921 cgacacgatc gagggcgacc acctttcgat aatggtcgat cccgcaactg aagtattggc
    40981 ccgcaggatt gagcgttggc tgtatcagct cagccgttga gggacgtttt ttctgaccct
    41041 tatccgccgg aatccaagat ttcagtggtg aggtttccta ataaaacagg acgtattgcc
    41101 ccatggatac tgaactttct ttagtgaact tcgatttcat tgtgatcggt ggcagctatg
    41161 ccggacagtc ggcggcaatg caactggcca gggctcgacg gcgggttctg gtgatggacg
    41221 tcggcgtgcg tcgcaaccgt ttttcccgga cgctacacgg tttgcccggg caggaggggc
    41281 gctcacccga tgtcattgcg caggaggggc gggcgcaaat catcgcttat ccgaatgtgc
    41341 agtggttgga agaggaggcc acaagtgctg agcgcaccaa ggccggattt gtcgtccgag
    41401 ctcagtcggg gcaaggtttt tttgccccga acgtggtgtt ggccactggt gtggaagacg
    41461 acttgccgcc agtggacgga ttggcccagc gctgggggcg tagcgtattt cattgccctt
    41521 attgccatgg ctatgaattg aaccagggct atatcggcgt gcttgcggtc gacgaagttg
    41581 cctatcaact tgcattgatg atgcttgatt gggggaccgt cattctcctc accgatggca
    41641 ggttcgaacc cgatgaggct cagcgcaaga ccttggcaga atgtggggtg gtgattgagt
    41701 cgcagcgggt gctacgcata gtggatacag ccactgtcga gttggacgat gggcgaaaaa
    41761 tcgtcttgga tggtttgttc tgtgcgagtc acacccgtat ggcgagcccg attgccgcac
    41821 aactaggctg cgccttcgaa gagggggcga tggggcccta tatttgcacc agcgaaacca
    41881 tggaaacctc tgtccctgga gtatttgcct gcggtgacat ggttcgcatg gggggaactg
    41941 tcggcctggc cgtggggtca ggcgcccatg ccggacttgc cgcgcaccgg gcgtcagcgc
    42001 aacggtgacg ccgtgtgtta ttggctcggt tccctgttta aagtcccgac ataaggagca
    42061 tcgtcgtgag ttggcaaaac tggtgtattt cctggctatt acgcctgaag gtaaaaccct
    42121 tgattgccaa gcctggatta tcggttcagg acatgcgcac ccatagcgat aaaggggttc
    42181 gcctcgtacg tcccccgaag gggtggcaca tacgcgagag cactgaggcc agtggggagt
    42241 gggtcgagcc gcaggacccc gttcaacgtg acaggcttca ccgtgtcgtc atgtacttgc
    42301 atggtggtgg ttattgtttt tgctctgcga aaacacatcg tgggattgcg tgtgcattgg
    42361 ctagcggtgc tgaggcgcgt accttttcgt tggattatcg gctagctccg gagcatccgt
    42421 tcccggccgc ggtaaacgat gctctggccg cctatcggca gctacttgcc gaaggtgtct
    42481 gccctgcacg catagtcatt tgtggtgatt ccgcgggcgg gggcctggcc ctggcaatgc
    42541 tgttgtcatt gcgcgacgcg ggtgagccga tgcctgtagg cgcagtgctg ttttcgccgt
    42601 ggacagacct ggctgcaacg ggaggctctt tgacaacgaa taacccgagc gacgtgatgc
    42661 tgactggcgc agccgtcgca aggttttccc ggcattatct gaacgatacg cctgcggacc
    42721 atcccattgc ttcaccactc tatgcgcagt ttgctggcct gccacccttg ttcattcaag
    42781 ccagtgacac cgaggtgctg ctggatgatg ccgtgcgggt tgccgaaaaa gcccgtctgg
    42841 ctcaggttgc ggtgaacttc aaagtctggc cccgcctccc gcatgcctgg ccgacgatga
    42901 cccctttcct gccggaggcg aaggaggccg tcaaggaggc cgttgatttc atccgaagtg
    42961 tgacgggatg acactgttgg agcaatgcgg cggcctcgac ctgaatagct tcatgagcgg
    43021 cagtgggggc tggacaggtc gcaggccttt cgagcttttg cgcggcgtat ttcaatcttt
    43081 attgttcaag ggcaaacaat gatgacgatg atgcaatcta tctactcctc gctgttgtgg
    43141 gctacaacgc ctcatatggc agcagatgca cgagggtttc gatgcacggt tcatggcgtc
    43201 gttgcggcta catcgtgctg gcgaggtcac acgcaatgac catcggatcg tttgactctg
    43261 tacctggcac atcaacaggc cagacccgcg tgaaattgtt ctgtttacct tatgccgggg
    43321 gcagcgcagc gatctttcgc gactggccat cacgactctc atcggagatc gaggtggttc
    43381 ccctgcacct gcctgggcga gggcggcgca tgcgtgaagc gttgctacat gacctgggtg
    43441 agatcgccaa tcaggtggtt gacgccatcg caccattgct tgaaaagcct tatgtcttgt
    43501 tcggtcacag catgggagcc tgcctggctt ttgaggttgc gcgccgcctg cgtgccagtg
    43561 gcctgccgaa gccggcttgc ttgatcgtgt ctggccacag ggcgccgcat ttgccagcca
    43621 gtcgttcatt actgcatgga cttcccgatg acgagttcat cgacgaagtg atgcgtttga
    43681 acggcacgcc acctgaaata ctgaagcacc ctgaagtact cgatttgatc ctgcccatcc
    43741 tgcgtgctga ctttgaggcg gtggagacct accgcatgac cccagagcca cctcttgcct
    43801 gcaggattgt tgcgctgggg ggggataacg atcccggaat ggacagcgac gctgtggcgt
    43861 cttggggcat ccacaccacg agcagttttt attatcagat gcttcctggt gatcattttt
    43921 tcctgcatgg cagtgctgaa cagatgtttg ccttgatcaa ccaggaactg cggtctgtat
    43981 tgcttcaggt tcgatccggt caacagggtg ttgccattga gccgacgggc tgaatgggtc
    44041 atgcaaagaa ccgctcattc agcaccagag gcgtctggaa ggccggtcca ctgtcaccga
    44101 tggtttgaag caataccgcg tgagactgat taatgcagtc caaggaggag taatgatcac
    44161 aacgtttatg tttccgggac agggctccca ggcgaaaggg atgggcgcag gattgtttga
    44221 tcgattcaag gagctgagcg ctcaggccga ccgtgtgttg ggctattcga ttaaagaact
    44281 gtgtctggtc gacccagggg ggcggttgag tctgacgcaa ttcacacagc ctgcgctata
    44341 cgtggttaac gcacttactt attacgccag gctcgaggat gacgctacgc cagcagactt
    44401 tgtggtgggg cacagtcttg gtgagttcaa tgcactgctc gcagccggct gctttgattt
    44461 cgagacggga cttcagcttg taaaaaaacg aggggagttg atgggccaga tatccggtgg
    44521 agcgatggct gccatcttga acgccaacaa gaacgacatt gaactcacac ttgcccgcag
    44581 cgggctcgat gacattggcg ttgccaatta caacacgcct tcacaattcg tcatctctgg
    44641 ccccgtcgag caaatcgagg caagcgaggc attgttccag aacgccccga tgcgttacct
    44701 gcgactcaac accagtggcg ccttccattc gaaactaatg caacctgcgg cggatgtttt
    44761 tgctgcgttt ttggacgcat tcacctttgt gagtccgata atccctgtgt tcgccaattt
    44821 ttctgcgcgt ccctacgaga gcaatcagat tgccgatggg cttgctaagc aaatggccag
    44881 tcccgtgcgc tggtgtgaaa gcgtgcagca tttgcttgaa tttgccgccg ggagcggcca
    44941 ggaagcctcg ttcgaggagc tcgggcacgg agaagtactc acgcgccttg ttcatgcgat
    45001 ccgtaggcag acgcctgttg ctgagaaccg ggtggtgtcc gatgccagtg cgctggataa
    45061 gcgcggccag ccgaatctat tgcctgtttt gggtacacag acttcaagtg cgcatgaaaa
    45121 ggtgacggca tggaacctca actgcccggt cggaacgaag gtgaggtcat tgttgattga
    45181 ttatccctcg ttggaaacat gtaccgaagc catggttttg tttgggcata gaccggtagt
    45241 ttatatgaaa gggtacaacg gttacttcga tatagatgaa gtgatgggtg tctgactttg
    45301 cccttcaggc ccaagcccgg attgccggtt ctgccgccaa ccacgatgag cgtcaacacg
    45361 ttctaagtgc aaccccaagc aagcaacctg ccttgaaaat acgggctctg gtttcccggt
    45421 taccctgggg gggcagcgcg gatattgctt tcagggctat tgacagacct ccaacacctt
    45481 gagaatccgg gtcggccttc tgatcgttcg agagagggct taattgggaa agtacttgtg
    45541 cacctcttcg gtggtatcgc gcagaaggat ctgcacagcc tgcggaatca ggcatcgtat
    45601 gagtcgcaaa acattatagc cgggcagaat acgtactcgt cggtgtttcc agcacagccc
    45661 aatggtaacc tcagtccgcc gaccatcaga cgggattggg aaccatggcg cagagggatg
    45721 attaccgcgt caagtcacca ctggaaatgc tcaacgtatt caacctttgc gtgctcgagc
    45781 ttgcccgtct tgctcgatca cgcgcaggct ctcatttcat cgcagagggc ctgcagacat
    45841 ttcgtccact ggtgcccttc acttcggcct ggtggggcga gatgtccaac acggacgcca
    45901 aggctgcgcc gcaaagttgg atgcacgggc gcatcaacct gcctgaatcg tttgccgccg
    45961 aatggagcac gattgccggc cgcgacagtt tcgcccatga cacgctgaat cgaccgggca
    46021 aggtcgtgcg cgacagtgag ttcaccgacc ctgacgatca ggtgaatgtg tttgcacggc
    46081 gctatgacct ctaccacctg atgtgtatca ccttcgagct gcctgaaagc ggcttgatgt
    46141 tctttgtctg tctctaccgt ggccttgatg caccggcttt caacgagacg gaggacggtc
    46201 tgttttcggc cttctgcgac cacctgttgc aactgtggcg gtttcaagtg caggacatga
    46261 ttcgcttcga cacggacaac ggggcgacgg atttcggtgt tgcccgtatg gacggcagtc
    46321 tgttgtatgt gggtgccagg ctgtgcgccg ccattgagcg tgagttgccc ggctggagcg
    46381 gttcaatgct gcctgaacag gtgattacgc aactgcacga tgcaccgggc gtggtgcgtc
    46441 tgggtcgctc gtcattgaca ctcagccccc atggcgagca tgtgattctg tcacttgagg
    46501 tgccgtcggg cggggcagcg ctcgcgccac gggagcgcac ggccgcgatg ctgttcgccg
    46561 ccggccactc ctacaaggag atcgccaaaa tgctgtcgtt gagcccggcg acggtgcgta
    46621 cctacctgcg caattgttac ctgcaactgg gggtcaaaag caaagtggag ctagggtccg
    46681 tgctgcgtgc ggttgtccgt cgcgattagc gttggttgcc ccggcatttc agttaattgc
    46741 cttacccctc ctcatttgtg gaggtccgtt ttctggtcgc tctctataag gtatggctat
    46801 cccaagccgc ccaattaaaa caagagagtg ttccgatgca acgatttgtt cccagtctgt
    46861 tggccgccgc tgtggcgttt tcctcggtgc aagcgatggc cgctgctgac cttgtgctgt
    46921 tcaacggcaa ggtattcacc gctgagtccg gacaagaact ggttcaggcg gtggcggtgc
    46981 aagacggcaa gattcttaaa gtaggcagcg atgccgagat cacggccttg gccgatgacc
    47041 atacgcaacg catcgatctg gccggcaagg tgctgatgcc gggcatgatt gatagccata
    47101 gccatccggt ggtcgcagcc ttcgacagcc tgggcgccaa cttgctggac gaggtcaaac
    47161 cgttacctgc gcttgagcag tggatcatcg agcaggacca ggcgggcaac gcgagggcag
    47221 gggacgtggt cagcattgcc ggggtcagtt cggcctattg gcaacagagc aaggcgcttg
    47281 gcgagcgttt caatcagggg cgttgggctg aacaaccgct ggtgctgaat gggattgacg
    47341 gccacaccgg ctgggccaac aacgccatgc tcaagcgctt gaaaatcgat gcagcgctgg
    47401 taaaaagcct gccggaagca gagcgtggtt atgtgggcca cgcagcggac ttcacgccca
    47461 atggttattt tgccgagtcg cgttgggatc aggtgcgcag ccagattcct gcacccagtg
    47521 ccgaggtcat gttgaaggct gcccgcctgg cggtgcagat caataatcaa tatggcgtta
    47581 ccgcctggat ggacgcagcg tcgaatgccg gccaaggtga ttcgctgttt gatttcacgg
    47641 caactgagca gagttacggt gtgctgccgc tctaccgtga actggcagag aaaggggaac
    47701 tcagcgcgca cgttgcggcg ttactgatca ccaacccgaa aagcaaaccg gccgacctgg
    47761 aagtactggc caagataatg aagacgttcg agggcgtgcc caacctgacc ttcccgggca
    47821 tcaaggtttt tgcagacggc atcatggagt ttccagggca aaccgctgcg gtgatcgacc
    47881 cgttcaagaa cagcctgaaa aacggccagc tgttaatcga cccggcgcac tttggcgagt
    47941 tggtggtggc ggcggaaaag cgcgactgga tcgtgcacat gcatgctgtt ggcgaccgcg
    48001 cggtccgtga gtcactcaat ggctttgaat acgcgcgcaa gcttaatccc acgccaatgc
    48061 cccatagcat cagccacctg caactggtca accccaagga gtttccacgc ttcaaacagc
    48121 tgggtgtgat tgcctccatg caactactct gggccaccgg tgaggactac acggtgaagc
    48181 tggtcaaacc ctatgtcagt gcgtttgcct accgttacca gtatcccgcg cagtccctgc
    48241 ataaagccgg cgccatgatt gccggagcca gtgattggcc ggtgtccagc cccaacccgt
    48301 ggaacgccat tgctcaggcc agcactcgaa agggaccgct gggggtgttg aatgccaagg
    48361 aaagtattga ccgccagacc atgttttacg cctacaccct caacgctgcc aaagccctgc
    48421 gcctggatca gcagattggc tcactggcgc ccggcaaaca ggccgatctg atcatccttg
    48481 atcgcgatgt gttcaaggtc agcgacgacg aactgtttga cacccaggtg ctgaagacct
    48541 tcttcgccgg caaacaggtc tacgcgcccg cgtcctgacg atcgacccct cctgaacagc
    48601 caagcctctc gtattgcgag gggctcggca cgggtgtgcc cgaatttccc cgctcactta
    48661 taaaaataag agatacctat gaaagcactc tcagtctttc ttgtgttggt gccattgacc
    48721 acgcaagcgc tgccgctcaa cgatgacctc aacctgcagg tcagcctggc cgccgtcagc
    48781 gactatcgca cccgtggcat ctcgcagacc ctgggtgatc cggcggtgca ggcaggcgtc
    48841 acgttgctgc atggcagcgg cctgtatgcc ggtgtctgga cttcgaatgt cgattttggc
    48901 gatgacttca agacacgcga agaatttgaa tactacgcgg gctatgcctg gcagatgacc
    48961 gatgccatca gcctcgactt gggctacatc aagtacagct atcccaagga aagccaattc
    49021 aacctgagcg agctctacgc gatcctcgac acctatggcg tgcagcttgg cgcctattac
    49081 tcccgcgata cgccgaacgc ctttggcgac caccagtcca ccctctacac ctaccttggc
    49141 tacaccacca ctttgccagg tgaggtcggc ttgaaactgc gttatgggca caacgacgtt
    49201 aaggatccgg cgttctggtc cacccgtggt gatgcgcgtg attcctacca cgagtgggaa
    49261 gtcgccctga cccatgattt cgtgggcgtg acctggggcc tcagctacat cgataccgac
    49321 ctgtcgaaaa gcgaatgcgc aggctggtac ggctatggcg acctgtgcac ggccactgtc
    49381 gtggccagtg tcagcaagac gttctaaggg gcgtgctttt caaggtctac agcgccatta
    49441 agcaaacccc agctcaaggc cgcgaagatc aactgtggga gttgtcgagc tttagcgagg
    49501 ctacgatgac gtcggcacag ccaacattgc tgttgcctga cccgccgcta tcgcaacctc
    49561 gctggggctc gacacaccac aagggtttcg cttcgacggt tagatcttcg ttgagtggga
    49621 aattgtctgt acgtgctact tactgacttt caccccgttg aataacaaca gcagcaacac
    49681 cccggccagc acttcaaaac aggcgaccag atacaggccc gcggacaagc taccggtcag
    49741 agttttcagc cagccgatca tgtagggcgc aacgaacccg gcaaggttgc cgatgcagtt
    49801 aatcaaggcg atgccgccgg ccgcagcggt accggccagg aaggcccctg gaatcgacca
    49861 gaacactgga aacgctgcca ggatacccat ggcggccagt gtcagggaga ccagcgctaa
    49921 cacggcatgc ccgataaaca gccctgtgca ggccagccct aggccggcga gcagggcggc
    49981 catcgcacaa tgcacacggc gttcggcgct cttgtcagag tgaaagccgt tccacagcat
    50041 cgccccggta cccaatatga aggggattga ggagagcagg ccgatgttca gggtgtcatc
    50101 gacgcccaac gacttgatga ctgacggggt ccagaaggca atggtcgcgt tgccgctgac
    50161 caggcagaag tacaccagcg cacatagcca cagtttggga tagcgaatca gcgagcgaag
    50221 atcgctgtgc ttgccgggcg ccttgtcttc gcgggcaatc gtgtcgctga ccattttgcg
    50281 ttgtgccggg ctcagccagt tggcattggc cggtttctcc gggagatagc acagtaccag
    50341 gaagccggcg atcaccgacg gaataccttc caggatgaac aaccattgcc agttggccag
    50401 gctgccaacc ccgaccatac gactcatgat gagtccggca agcggcccgc caaccacgcc
    50461 ggcaatggcg aaggaggtca tgaacatgcc gttgattttt gcgcgctgcg ctgccggaaa
    50521 ccagtaggtg aggtacagca cgacgccggg aaagaagccg gcttcaaaag ccccgagcag
    50581 aaaccgcagt acatagaacg accacgcgct ttcgacgtac gccatggcga tggacgtcag
    50641 gccccacatg atggtgatgc gcgccagggt gcggcgggcg ccgattttct ccaaaagcaa
    50701 attgctgggc acttcgaaga agaagtaacc gatgaaaaat attcctgcgc ccagaccata
    50761 aaccgcttcg ctgaagccca ggtcctgcaa catggccagc ttggcgaagc cgacgttaac
    50821 ccggtcgatc caggccagta cgaagagaaa caccaggaac ggcagaaggc gccaggcaat
    50881 cttgcgatag acgacggcca cttcgtccgt tactggtgca gggcctagct ccagggttga
    50941 acttgcgttg cttcggttca tacgttatct cgtcaattcg ttgcgcagca gggcacgcaa
    51001 gccgattggc aggcgagtgg aggcgcacga ggggccgccg tgtgattttt ttcggtgagt
    51061 cagtcaggtc acacagggca ggtcaggcct gccctgtgtt cagcggccgt gcatcaggtg
    51121 ctttctcgta acagtgcctc gaccgcgcgc gacacttgca ggacccgagt gtcctgccca
    51181 tgcaggccgg caatcgacag cccgaccggc agttcgtcgc cgcgctggca aggcaggctc
    51241 aaggcgcaac cgtcgaggaa gttgatcacg ctggtattgc gcaatacgag gccgttggtg
    51301 gcaaaaaaag ccgcgtcatc cgccaggtct gccagcttcg gtgggaccac ggcgacactg
    51361 ggcagcaacc aggcatcggc gtcgcccagg cgctcgcgcg ctacgctgat caggcgttgg
    51421 cgttcggttt gaatgtccag gtaatcggcg gcactgatgg ccgcgccacg gcgaatgcgt
    51481 tgagcgacac gtgggtcata acgctggctg ttgtcacctt cgagccactg gcgatggccg
    51541 tgccaggctt cggcggcggt cagcccaccc gctgcgttga tgcgcggcag gtcgtgcagt
    51601 tctggaaagt cgaaccagcg tatacaggcg ccggccttgg cgagcaggtc cagggcgcgt
    51661 tcgaaggctg aggcgacgcc ggcatcgagc tgatcgagga caaaatcccg ggtgaccgcc
    51721 aggcgaagcc cggccaaggg tacggcgcgg gtatccagtt gctcgccgct aagaatctgg
    51781 tccagcagga tgctgtcggc gacgctgcgt gacagggcac cgacagagtc caggctaatg
    51841 gccaagggga aggtacctga catgggcacg cgactggcgc tgggtttgaa cccggtcagg
    51901 ttgcagaagg cggcggggat tcgaatggaa ccgccggtgt cggtgcccaa gccggcgacc
    51961 gccatgccca gtgccacgct cacggccgcg ccggagctgg agccaccggc gatacgccca
    52021 gccgcacacg gcgtgagcgg ggtgccgtag tgggggttca ggcccaaccc ggaaaaggcg
    52081 aactcactca tgttggttcg gcccagtaaa atcgcaccgg ccgcccgcag gcgttggacc
    52141 gccagcgcat cgctgcgggc gggtggtgcc tcggccagca accgcgagcc ggccgccgtg
    52201 acttgcccgg ccacgtcgaa caaatccttg atggacaccg gcagccccgc cagcggcgag
    52261 ggcacgtagc ccgaagcgcg ggccagatcg ctggcccgtg cagcctgcaa ggcgccttca
    52321 gcatcgacgc tgatataggc aaccccgcct gccgcgcgat gcgcctcaat gcggctcaac
    52381 gcgtccttga ccaaggcttc gctggtggta cggccctcag ccagcgcttg ggcgaactct
    52441 gcaatctcgt tcatcgtagg ctcactcggc gacaggcagc ggctcgacac cgtattggtg
    52501 acgcaggctg cggttgagga tggggtcgaa caattccatt tcaaaggctt cgccgtagcc
    52561 cagttcgccg atcaccgatt gcgtgccgca aaacatcgcg gtgtcggcgg gcaacgaggc
    52621 ttcgtggttc agttttgcca acagggtttc cggagccagc aggttggtca ccgggccttg
    52681 ttggtagagc gcacgcacac cgtcacgcac gcgccaggtg cgcatgacca gttggtccca
    52741 atgcccctgg acttcgctgt agcgccacac ttgctgggcg ataggcttgt cgcacatctg
    52801 cttggacacg gtgacgtcat agctttcaac cttgcggtcg gtgtggtccg aacccaggcc
    52861 gatcaagaga ccttgctcgc tgggcaggag cacgaactca gtttccccgg aggagtcctt
    52921 gccaggcacc tggatggtct cagcattgtt cagcaggctg gccgataccc ggtagaaaca
    52981 cggaacctga gttgggcggc gcacccccag tgcttcgagt tcggcgatgt gatgctccac
    53041 cgcttcgctg ttacgtcccg cccagcccgc gataatcagg tgcttgatgc tggcgcggtg
    53101 ttcgccctgg ccgacgacgt ggaaggtcaa ttgagtcatg aaaagctctc gtggtgagtg
    53161 attaaagcgt gcgcatgatg gcgcgacgga aatcgtcaat gtggtgatgg atcgcagcaa
    53221 cggcggcggt gccatcacgc tgttccagcg cctcaaggat ttgcaggtgt tcgtggtaga
    53281 tgcgttcgct gtggtggttt tccgacaggg tcaggtacca gaagcgcgcc tgtttttcgt
    53341 gaaggttgcg cagcaactcg gccagcacgc ggttgtgtgc ggcagccgaa atcgccatgt
    53401 gaaactgcag gtccaacgac atcagcccag tgacgtcgtg tttcgccagc aacgcggggg
    53461 tttgctcaag aatgtcgcgc atggcctgaa tgtcagcgtc atgggcacgc tccaccgcca
    53521 gctttacgca gagctgttcg ttgctcacgc gcacttcgat catgtcgagc acgtcattga
    53581 gtgacagggc cgttaccatc acgcccttgc gcggcatgat cgtgaccatg ccttccactt
    53641 ccaggcggtg cagcgcttga tggatagggg ttcggccaat acccagcgcg gtaatcagtt
    53701 gcgcttcatt gatcgcatcg ccagggcgaa actcgcagct gatgatccgc tgcttgattt
    53761 gtgcataggc caattcgcgc agttgggcag cgctttttgt gggagccatc gcgatctggc
    53821 gatgaccgga aaagtcggta ggttcggaca tgttcgctcc tgaaaatcat ctgatatatc
    53881 agatgatttt cagaacgaag caatgcctgt gccagttttt caggaactgg ccaaaggcgc
    53941 ggtttataag ggattggcgg aatcagcggt acgctggagg gcagggcggg cgatgttgct
    54001 tgttactttt gtgcccggct ttgagccggt gtgctcgatg tttgtgcggg cgaggtatca
    54061 acttaaaggc gctctgggag gacctggcgc atcatgccgt tgcgcctttc aagaagatcg
    54121 agatgagaaa ctcgggccct tggcgtttgc ccatcgactc atcgtcgatc aggtctgacg
    54181 tggtttcgca cagcccctga aatgcccccg tcatccaggc tgccggaagg tcctggcgaa
    54241 acagcccggc ctgctgaccc cgctcaaaga atgcaacgag ccgggcatta attgtttcga
    54301 cccgcgccgc caggtcggac agcaacgtct cgata
//
