LOCUS       BGC0001047             22119 bp    DNA     linear   BCT 25-JUL-2016
DEFINITION  Pseudomonas syringae slyABCDE gene and ORF1, ORF7 and ORF8.
ACCESSION   BGC0001047
VERSION     BGC0001047
KEYWORDS    .
SOURCE      Pseudomonas syringae
  ORGANISM  Pseudomonas syringae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:45:25
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22119
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[6216:18789]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6217..18789
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     protocluster    1..22119
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2125:18789]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      2126..18789
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
     cand_cluster    1..22119
                     /SMILES="NC(C(C)C)C(=O)NC([*])C(=O)NC(C(C)C)C(=O)C=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="chemical_hybrid"
                     /product="T1PKS"
                     /product="NRPS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..22119
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001047"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..22119
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            2..718
                     /gene="sylA"
     CDS             2..718
                     /codon_start=1
                     /db_xref="GOA:Q83Y51"
                     /db_xref="HSSP:P11470"
                     /db_xref="InterPro:IPR000792"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="UniProtKB/TrEMBL:Q83Y51"
                     /gene="sylA"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1197:autoinducer-binding transcriptional regulator,
                     (Score: 202.3; E-value: 1.2e-61)"
                     /gene_kind="regulatory"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /product="putative HTH_LUXR domain-containing transcription
                     activator"
                     /protein_id="CAD70192.1"
                     /transl_table=11
                     /translation="MMALSLRGDTVGHEKSTGRQKLEWEFEQSASERGVHHYTYFFYHH
                     APALRQHGFVLVSGPEAGKNNSHCAERQDVADAIWDVACSEPLFTGLLNRPTSSNDRGE
                     MIDAGTTSDGMTAFYLGEEKAFSLLRFANKETGTGSTQGEYSLAAEVKSLVREFHHKLT
                     GLVMGVNESDETFTITDREKEVYIWTAIGKTCNEIAVILNISKRTVDFHISNVISKLGV
                     RTKLQACIQLTKMGIL"
     gene            complement(870..1922)
                     /gene="sylB"
     CDS             complement(870..1922)
                     /codon_start=1
                     /db_xref="GOA:Q83Y50"
                     /db_xref="InterPro:IPR005804"
                     /db_xref="InterPro:IPR010257"
                     /db_xref="InterPro:IPR012261"
                     /db_xref="UniProtKB/TrEMBL:Q83Y50"
                     /gene="sylB"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /product="putative desaturase"
                     /protein_id="CAD70193.1"
                     /transl_table=11
                     /translation="MQTVQRFHCTNALKLELTCLYKKNNWRWLLGWSGDVLVIASAVAL
                     TQWSLYAYPLSVLIIGSRQRALASLVHEAAHLTLTQSRRLNYAIGHYLTGLPIFQDYEA
                     YRHSHVHMHHHHLGDADKDPDYRYYIESGLQATEDRFDFMFNHLLRTVLFLNIFSYLRY
                     LVIHRLGALLKSPRKALTLIAVHAVLFSLFYATTGVYGYLMFWLVPYLTAFQVIGWLSE
                     VSEHFGLFGREQEALRITRNRFPSWWERLFIGMHGDNLHLTHHLFAGIPYWNLHKAHSI
                     LLQDPDYAEANLAKGGIISGRRDTQSVMRQILSIYRLQNRRHSPYGTAPQTLCEQSARE
                     GTQTTNGDDR"
     gene            2126..6112
                     /gene="sylC"
     CDS             2126..6112
                     /NRPS_PKS="Domain: Condensation_LCL (36-338). E-value:
                     1e-74. Score: 243.1. Matches aSDomain:
                     nrpspksdomains_sylC_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (750-1144). E-value:
                     2.1e-91. Score: 298.4. Matches aSDomain:
                     nrpspksdomains_sylC_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1253-1322). E-value: 2.4e-23.
                     Score: 74.0. Matches aSDomain: nrpspksdomains_sylC_PCP.1"
                     /codon_start=1
                     /db_xref="GOA:Q83Y49"
                     /db_xref="HSSP:O30409"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="UniProtKB/TrEMBL:Q83Y49"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /function="involved in syringolin A synthesis"
                     /gene="sylC"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     54.5; E-value: 1.9e-16)"
                     /gene_kind="biosynthetic"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="CAD70194.1"
                     /sec_met_domain="Condensation (E-value: 3.2e-60, bitscore:
                     192.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.6e-97, bitscore:
                     313.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.5e-16, bitscore:
                     47.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSEAVMNSFEKNNTAPSRSQDLAMRAGAQHITGTEGPLSMSQEQ
                     AWFLETLVPESIAYNFQAMLNIRGNLDINVLERALNRVVERHQSLSTVFDEVDGEPRQT
                     IQDAWSVNIPIVDLSASSEAVRQTYMNSIVKAEIAQKIEVAKLPLIRWVLFKFSDQFHV
                     LLHIEHHLIHDGWSFRLFLKELNHFYNEEKGRANQEPLEPVIQFIDYCQWERDWLDSAE
                     GRQGRDFWYGRLETWPAYTHSPFPAEKDAQAALDFVGSSVSVPLPGKLISALQAYGSEN
                     KSTLFETMFSLFACVVAARSGQTQQLIGTAVANRDLPGIENTIGMLVNMLPLRIDIDAN
                     TSWAPLLAAVKEEIRTACLQSHVPFSTMVADLSPDRVTQQLPYIQVAFSFHNSMSRTLD
                     FADIDVEVVEGLANGSAKFDLNVICVFDDEVNPAAGGRFMLEYSTAVAKEADVRALMAD
                     FLHLAGAWLEQPAESLANVRKAAVLAAPSGSSSVNPGVEFWKQSLDLEASGLLPDHALN
                     RAVSGPLARHEIPLPDESLARLFQACEQRNIEPEAALFSLYAVTMARYGGHQTVVAGLG
                     TAADGQRLAIPLPLKLTLAAHDTFADVFLRAQQHCEQARHWHKSSAQGLEQALDDSVAA
                     SGRAPQSLIQSVFCDGVSARAEQGGASGSLHSPLEFVLDRSSTKASLSLGYAADLFAQE
                     TATSMAGHYVQLLEKASESLDETLAQSLSAQHQAAIQTQCEGLDSSYPETSLHAIVEAF
                     AATQPEAIAVRCGDAVLTYAQLNESADKVADTLLRKGVQPGDVVGICMMRSELLVAALL
                     GVLKAGACYLSIDCALPAERRNWLLEEADVKWALIDESAPALRDATSTLLIGQLVNEQD
                     DPRVSPLAKPVISADARCYYMFTSGSTGTPKATASTHRAVVSLVKGTDYIDIKGDDRFL
                     FFAPLAFDASTFEIWGALLNGAQLVVQPGEAGGLDDLAHTLENQQVSVLWLTSALFQEM
                     VDQYPQAMAGVRHVLTGGDVVSPQSMRSLLARSTGTLTICYGPTEGTVFTTAYSMDKVE
                     QVTDKPLIGWPIAQADAYIVDVFGQLAEPGVPGELFIGGTGITGAYLKRPELNQERFVT
                     LERFPGKTLFRTGDLARWTPGRGIEFLGRSDSQIKIRGLRIEPGEVEQAIRQLPGVTAC
                     SLILRTLNLDKQLVAFVSLDGSVALDEQQIRVALRECLPDYMVPAEVHVIEQLPVNASG
                     KVDKRALLELATQNGRARVTSERPSTALEKSIAEVWAHILNVPDVGRNEDFFSIGGHSL
                     AGMRIMSRLSKQFGTRLSLNLLFEYPSVETLAGAIERSAEPLTA"
     aSDomain        2234..3139
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylC_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.00E-74"
                     /label="sylC_Condensation_LCL.1"
                     /locus_tag="sylC"
                     /protein_end="338"
                     /protein_start="36"
                     /score="243.1"
                     /tool="antismash"
                     /translation="GPLSMSQEQAWFLETLVPESIAYNFQAMLNIRGNLDINVLERALN
                     RVVERHQSLSTVFDEVDGEPRQTIQDAWSVNIPIVDLSASSEAVRQTYMNSIVKAEIAQ
                     KIEVAKLPLIRWVLFKFSDQFHVLLHIEHHLIHDGWSFRLFLKELNHFYNEEKGRANQE
                     PLEPVIQFIDYCQWERDWLDSAEGRQGRDFWYGRLETWPAYTHSPFPAEKDAQAALDFV
                     GSSVSVPLPGKLISALQAYGSENKSTLFETMFSLFACVVAARSGQTQQLIGTAVANRDL
                     PGIENTIGMLVNMLPLRIDID"
     aSModule        2234..6091
                     /complete
                     /domains="nrpspksdomains_sylC_Condensation_LCL.1"
                     /domains="nrpspksdomains_sylC_AMP-binding.1"
                     /domains="nrpspksdomains_sylC_PCP.1"
                     /locus_tags="sylC"
                     /monomer_pairings="Val -> Val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2297..2407
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylC_0001"
                     /evalue="5.90E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="sylC"
                     /protein_end="94"
                     /protein_start="57"
                     /score="47.6"
                     /tool="antismash"
                     /translation="AYNFQAMLNIRGNLDINVLERALNRVVERHQSLSTVF"
     CDS_motif       2630..2692
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylC_0002"
                     /evalue="3.20E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="sylC"
                     /protein_end="189"
                     /protein_start="168"
                     /score="26.1"
                     /tool="antismash"
                     /translation="HHLIHDGWSFRLFLKELNHFY"
     CDS_motif       2741..2779
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylC_0003"
                     /evalue="6.00E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="sylC"
                     /protein_end="218"
                     /protein_start="205"
                     /score="9.5"
                     /tool="antismash"
                     /translation="QFIDYCQWERDWL"
     CDS_motif       3044..3127
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylC_0004"
                     /evalue="8.30E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="sylC"
                     /protein_end="334"
                     /protein_start="306"
                     /score="37.5"
                     /tool="antismash"
                     /translation="LIGTAVANRDLPGIENTIGMLVNMLPLR"
     CDS_motif       3206..3295
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylC_0005"
                     /evalue="1.70E-05"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="sylC"
                     /protein_end="390"
                     /protein_start="360"
                     /score="17.1"
                     /tool="antismash"
                     /translation="SHVPFSTMVADLSPDRVTQQLPYIQVAFSF"
     CDS_motif       4178..4213
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylC_0006"
                     /evalue="2.30E+01"
                     /label="C3_starter_134-155"
                     /locus_tag="sylC"
                     /protein_end="696"
                     /protein_start="684"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="GYAADLFAQETA"
     aSDomain        4376..5557
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylC_AMP-binding.1"
                     /evalue="2.10E-91"
                     /label="sylC_AMP-binding.1"
                     /locus_tag="sylC"
                     /protein_end="1144"
                     /protein_start="750"
                     /score="298.4"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="EAFAATQPEAIAVRCGDAVLTYAQLNESADKVADTLLRKGVQPGD
                     VVGICMMRSELLVAALLGVLKAGACYLSIDCALPAERRNWLLEEADVKWALIDESAPAL
                     RDATSTLLIGQLVNEQDDPRVSPLAKPVISADARCYYMFTSGSTGTPKATASTHRAVVS
                     LVKGTDYIDIKGDDRFLFFAPLAFDASTFEIWGALLNGAQLVVQPGEAGGLDDLAHTLE
                     NQQVSVLWLTSALFQEMVDQYPQAMAGVRHVLTGGDVVSPQSMRSLLARSTGTLTICYG
                     PTEGTVFTTAYSMDKVEQVTDKPLIGWPIAQADAYIVDVFGQLAEPGVPGELFIGGTGI
                     TGAYLKRPELNQERFVTLERFPGKTLFRTGDLARWTPGRGIEFLGRSDSQIKIR"
     CDS_motif       4559..4600
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylC_0007"
                     /evalue="2.10E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="sylC"
                     /protein_end="825"
                     /protein_start="811"
                     /score="11.7"
                     /tool="antismash"
                     /translation="LGVLKAGACYLSID"
     CDS_motif       4793..4849
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylC_0008"
                     /evalue="4.30E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="sylC"
                     /protein_end="908"
                     /protein_start="889"
                     /score="19.4"
                     /tool="antismash"
                     /translation="YYMFTSGSTGTPKATASTH"
     CDS_motif       5354..5440
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylC_0009"
                     /evalue="3.00E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="sylC"
                     /protein_end="1105"
                     /protein_start="1076"
                     /score="35.5"
                     /tool="antismash"
                     /translation="PGVPGELFIGGTGITGAYLKRPELNQERF"
     CDS_motif       5522..5587
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylC_0010"
                     /evalue="1.00E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="sylC"
                     /protein_end="1154"
                     /protein_start="1132"
                     /score="33.6"
                     /tool="antismash"
                     /translation="FLGRSDSQIKIRGLRIEPGEVE"
     aSDomain        5885..6091
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylC_PCP.1"
                     /evalue="2.40E-23"
                     /label="sylC_PCP.1"
                     /locus_tag="sylC"
                     /protein_end="1322"
                     /protein_start="1253"
                     /score="74.0"
                     /tool="antismash"
                     /translation="EKSIAEVWAHILNVPDVGRNEDFFSIGGHSLAGMRIMSRLSKQFG
                     TRLSLNLLFEYPSVETLAGAIERS"
     gene            6217..18789
                     /gene="sylD"
     CDS             6217..18789
                     /NRPS_PKS="Domain: Condensation_LCL (29-322). E-value:
                     1.1e-93. Score: 305.4. Matches aSDomain:
                     nrpspksdomains_sylD_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (487-899). E-value: 4.2e-93.
                     Score: 304.0. Matches aSDomain:
                     nrpspksdomains_sylD_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1003-1069). E-value: 6.4e-24.
                     Score: 75.9. Matches aSDomain: nrpspksdomains_sylD_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1096-1401). E-value:
                     2e-88. Score: 288.1. Matches aSDomain:
                     nrpspksdomains_sylD_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1566-1956). E-value:
                     7.4e-95. Score: 309.8. Matches aSDomain:
                     nrpspksdomains_sylD_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2074-2140). E-value: 1.9e-18.
                     Score: 58.3. Matches aSDomain: nrpspksdomains_sylD_PCP.2"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (2165-2590). E-value:
                     3.3e-150. Score: 492.5. Matches aSDomain:
                     nrpspksdomains_sylD_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (2686-2967). E-value: 1.7e-87.
                     Score: 285.4. Matches aSDomain:
                     nrpspksdomains_sylD_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH2 (3068-3284). E-value: 2.8e-29.
                     Score: 94.0. Matches aSDomain:
                     nrpspksdomains_sylD_PKS_DH2.1"
                     /NRPS_PKS="Domain: PKS_KR (3559-3739). E-value: 1.5e-52.
                     Score: 170.0. Matches aSDomain:
                     nrpspksdomains_sylD_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (3826-3894). E-value: 3.1e-20.
                     Score: 64.0. Matches aSDomain: nrpspksdomains_sylD_PCP.3"
                     /NRPS_PKS="Domain: Thioesterase (3921-4179). E-value:
                     1.5e-29. Score: 95.9. Matches aSDomain:
                     nrpspksdomains_sylD_Thioesterase.1"
                     /codon_start=1
                     /db_xref="GOA:Q83Y48"
                     /db_xref="HSSP:Q8IVS2"
                     /db_xref="InterPro:IPR000794"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001031"
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="UniProtKB/TrEMBL:Q83Y48"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /gene="sylD"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     333.1; E-value: 5.2e-101)"
                     /gene_kind="biosynthetic"
                     /note="type I polyketide"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="CAD70195.1"
                     /sec_met_domain="Condensation (E-value: 5.2e-72, bitscore:
                     231.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-104, bitscore:
                     338.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4e-18, bitscore:
                     54.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 2.3e-155, bitscore:
                     506.5, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.1e-88, bitscore: 285.4,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 6.4e-45, bitscore:
                     142.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEMVMSQKKPVTSTTESAVRMPTPAAGGFLNLSPAQKSLWFMHQM
                     EDASATYNVPFALRIDGALDRAALERAVDSVYQRQSALRYRFPCIDGQPVIRLVDEQLL
                     IRKVDLRAEPDSEAALKAFEQSEARYVFDLEHEALLRATLLHCATDEHVLLINVHHIVF
                     DGWSMQIFLSEVASAYSALVRGSEVNAEPLNFDFGDYLSLSPSNAERAPDIDHWQRRLA
                     GAPPVLPLPLDNKRAAVQRYAGQRCHFQVPEAVSDALKNLARECRVTPYMVGLAAFSVL
                     LYRYTQEADLVIGSPMSNRQSSDLEGVIGFFVNTLPNRIDASGSPSFVELLKRVRASVL
                     DTFEHAHVPFDQIVEAIQPPRSLSHAPVFQVLFDMANEDFSVELENLRTRVYTLDSCTA
                     KYDLSLTLALTARGMSGAIEYDTALLDERAVQGMIDSLLIIMEQVSRNPDGAIDDFSLL
                     SCEAVEQALRLANHQPAAPQAPFAPFHQWFKRSAAQWGEADALVYENRRYSYAQLDAEA
                     RVLAGHLHAAGVRRGDRVAVVQRYGPEVIIALLAVHQVGGIYVPLAIDDARHADLLKDI
                     EPRLVLTLSACQEQLRGYPCLVQDDLPQATGTLHENEFEGRNTQPEDIAYIIFTSGSTG
                     RPKGVSVSHGSWVSLLQALEQTYGQTEPGVTGILQMANFTFDVFMSDVVRALAVGARLI
                     MCPRQSLADPEQLYELITAERVTLLEFVPAVLRQMIRYLEETGRRLDTLRTLTCGADVW
                     FVHEYRKMQTLCGPQTRVVSVYGVTEATCESATFEPDAGWYDPERSLPIGGPLPNTSLY
                     LVDATLNLVPRTVPGELLIGGGAVASGYMNRPELNEKSFLTGSFSASGRFLPGVGEQRF
                     YRTGDLCRHMRDGTIEFLGRSDNQVKIRGFRIELGEVESVLADHPDVNECAVVTRQSPG
                     AEAELIGYVQTRATAQQLNAYLGERLPGHMVPRLLVVLAALPLTANGKIDRKSLPEPDW
                     TQDSRAYAAPRNSLEEQLVEDWQHLLNVPRVGIDDNFFESGGHSLLVTQVIAQIKKRFG
                     VALSIANLFEGPTVAQVAEKIMLSMIQISQGASVASRPAAIGRSSGIERQRLSFAQRRL
                     WLTQHSEPGTAYNMPEICRLTGQLDIPALEGALNLLLERHEVLRTHFTRELETFVDTQG
                     VTQKEPLVVTSHADSARVPFRLQTIAREALTAALEVEVHTPFVLDKELPIRALLLQTAS
                     DEHVLCLTLHHIAYDGWSSALLRQELAVFYRHLTQGERITLSPLEAQYQDYAAWQRNQL
                     ETGAFTTQIDAWKASLQDLPPPLVLPVRSSPREGNPLAGDYVALTLPGDCSARLDQLCL
                     RLQCTPAMVMHAAFALLLHRYTGQDDILIGMPFSGRDHDESTNLIGFFVNLLPLRLRLR
                     GPLRVAQVIEQSRQALLAAEANQSVPIDYLAQVLNPQRLPGKHPFFQAGLVVQSTTAVP
                     LSLPHVKSEEISLASTEVKLDLMLELRAVKGEGVSGVFKYRTSLFERSVISGMAGHFQC
                     LLENMLANDEQTVAQVKMLSATEQQRLISQFNDTARDFGDGDVVSRFEQRVRQTPQAIA
                     LQLQQRCWTYAELDRLANGIAHALIKKGVQAGEHIGLFTGRHPYLVAGMLGILKARCAF
                     VPLNPQDSMEGALGYMIKDAALHRVVGHRGLAHELAALGLETLLVDDFEGDQREWSAPA
                     CQREPQDLAYILYTSGSTGQPKGVMVSQRNIDNTANAFARTLELTGQSRQLQYFSPVFD
                     GVCGEVFPVLISGATLVFAASEQLLPGPDLVTLLREQRITHLQITPTALRLLPHAELAE
                     LKVIISAGEACPANVAQTWAAGRRFLNGYGPTETTVYASARDYWDERGALVLRPLDNVR
                     MYVLDRYLNPLPCGVPGELYIGGSGVAQGYLNLDERTAQAFLPDPYGVSPEARLYRTGD
                     FVVRQFNGSLSYVGRIDNQVKIRGFRIELGDVETRLNAIAGLEQAVVVVKQDDQGHKAL
                     VGYYVGTPSVAQVRAELARVLPAHSVPERLVCLPELPLSRTGKVDRKSLENRVDQRAQE
                     GTAVGTPATLPAAVRPAGKRLHNTVRTIWQEVLDCQEIDSDDNFFDLGGHSLRIVETQK
                     RLSELLQAPVAMTDLFEYPTLRGLVAHLERLHGPLPEVGQASEASPAIDPGNRTLAVVG
                     MAGRFPGAADLSEFWQNITEGVESTLYFSDEVMLAHGVYPDLLERADFVKCGNRLEDVD
                     KFDAEFFGFSPREAQLMDPQQRIFLQCAWAAMEAAGYGGALNDLRVGVFASASTSHYLL
                     DHVYPRRQELQLENIQWLLGNGRDFMASRVAYKLNLAGPAITVETACSSSLVAVQMACE
                     SLLRGESDMVIVGGASVEAQYYGYQAAPGSIISVDGHCRPFDAQASGTTGGSGCAVLVL
                     KLADRAIEDRDHIHALIKGGAINNDGSSKVSYTAPSVHGQAQVVSAALDAANISADSIG
                     YVEAHGTGTRLGDPVEVRALTQAYTSALPHFTPGFCALGSLKSNIGHLDAASGIAGLVK
                     AILAVQHNVLPASLNFTRANPEIDFSDSPFYVNTTSRPWPAAASPRRAGVSSFGIGGTN
                     AHVIVEEPPQPSVRPHDDSERWYILPFSARSAAALDHQRRQLITCLQNPAADLRDIAFT
                     LGEGRTRFAFRDSVVSQSIAGALHALQAPSSTALMERRQDRPIVFMFSGQGSQYAGMFK
                     GLYDSEAVFRQTVDRCAVILQRYGVDILACLYPPAGSKTGDALSRTEIAQPALFVVEYA
                     CALLLQSRGIHPQALIGHSLGELVAACFAGVYSVEDSLKLVVERGRLMQRQAPGAMLAV
                     GLSEADCARFLEPGVELATVNGPLQCVLAGDFEAIARVERQLAEEGLVGRVLDTSHAFH
                     SRMMAPAAHALKAVVNGFSVQPPTIALVSNHNGGWFSIDSSSQSDYWASHLLETVRFSD
                     GIGLLADELEDPIFLEVGPGRALQSALKSYAEPLCVLGCTRHARDSRSDEAALAQGIAS
                     LWRQGARFGWAQATGCTDGARVPLPTYPFARDSHWIEAAGTASSAQHEAPLFLHWQRMN
                     GNRRQFRLSLSPQLWLVDEHRVFEGRPVLSGTGCVELVRNAYARMEGVESIELSDVYFP
                     TPLVLEDEQASQRVLITFKDHAESTEFFLESVSDEGNGPQQRTMLHAQGFIKRHDRERS
                     VPTALMQLQADHADCLADEVEHAALNTRLGLFGPRWKCFRSIWLSEDEGLALLELDQAF
                     AADVEHFALHPALLDMATGFLSIMENRARRLPFHYQRLTIHAPLRSRLYSHARRVRSNV
                     YDVQLFEVDSDGGVGALLAEVTGFTLREERVASEAQRTEPLDWCQAPAWRPALPPRSDS
                     PLQGPWLVVMRGVAADNSMLFSLPPDSVCIADAGDSGTAVATIARGDAQAYEQLFNTLA
                     AQDALPSQIIYMAGQAQPTHGEHAAIRLFTDLMSLVQAYIPHAANTTVLSLVTEGACQV
                     DDDEPVNSCVATLSGVVRTLAWELPQIQCRHFDLPLANAAENETLLLQALQHIDPDQAS
                     PLASTLALRKQTFHEPCLRALQVSPPSQPFEEGGTYVVTGGLGGMGLALASHLAAKAKA
                     VTLVLMSRSATVTDEVGQALQALEQQGARIQHMAVDCADREAFTAALHQVRLQHGRISG
                     AIHAAGVQASGLIQLSQATAWAQVMGSKVVGTDVLIEVLRQEPVDFIFLCSSLASVLGG
                     LGQADYAAANAYLDARAQACRQEGIPVVSLNWDAWAQAGMRVAYDRAHPEQAPIDDVRG
                     LTNAEGCQLFELALAQNTAQVIVSKAQDLQQLIEQLQRGGATSAGRATPLFDSGAERVA
                     PRNAVEQEVAQLWQELLGGDMPGVLDNFFDLGGHSLLGSQLISRIRSRFQQCLTLAEFL
                     DEPTIERIARSLGSGADDTPIDADEAAVRYCLVPVQRNGEGRPFFCLPGMGGNVNQVLG
                     LAKAMGTQRPFYGLQCLGLDGKAEPHLSVEDMAEHYIRCMKSVQAHGPYLLGGHSLGGK
                     VAYEIARRLEARGDQVGLLALFDSAAPPYTQMQVPTDAQVLGSLLSIFGHYFDKPIKLS
                     REELQALEHLDDEEKIRYLKDTLESHGLLDARGDEGSIRGLFNVYKAAAAFGMRYDPPK
                     VALDASLVLFRAVDSMPSGINLPEIRDTDAWGWESFSAAKVRTVDVSGDHFTCLSVHAR
                     QIADVLIEQLAECDR"
     aSDomain        6304..7182
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylD_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.10E-93"
                     /label="sylD_Condensation_LCL.1"
                     /locus_tag="sylD"
                     /protein_end="322"
                     /protein_start="29"
                     /score="305.4"
                     /tool="antismash"
                     /translation="LNLSPAQKSLWFMHQMEDASATYNVPFALRIDGALDRAALERAVD
                     SVYQRQSALRYRFPCIDGQPVIRLVDEQLLIRKVDLRAEPDSEAALKAFEQSEARYVFD
                     LEHEALLRATLLHCATDEHVLLINVHHIVFDGWSMQIFLSEVASAYSALVRGSEVNAEP
                     LNFDFGDYLSLSPSNAERAPDIDHWQRRLAGAPPVLPLPLDNKRAAVQRYAGQRCHFQV
                     PEAVSDALKNLARECRVTPYMVGLAAFSVLLYRYTQEADLVIGSPMSNRQSSDLEGVIG
                     FFVNTLPNRIDA"
     aSModule        6304..9423
                     /complete
                     /domains="nrpspksdomains_sylD_Condensation_LCL.1"
                     /domains="nrpspksdomains_sylD_AMP-binding.1"
                     /domains="nrpspksdomains_sylD_PCP.1"
                     /locus_tags="sylD"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6313..6345
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0001"
                     /evalue="8.50E-01"
                     /label="C1_LCL_004-017"
                     /locus_tag="sylD"
                     /protein_end="43"
                     /protein_start="32"
                     /score="3.3"
                     /tool="antismash"
                     /translation="SPAQKSLWFMH"
     CDS_motif       6364..6480
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0002"
                     /evalue="6.50E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="sylD"
                     /protein_end="88"
                     /protein_start="49"
                     /score="47.5"
                     /tool="antismash"
                     /translation="ATYNVPFALRIDGALDRAALERAVDSVYQRQSALRYRFP"
     CDS_motif       6688..6753
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0003"
                     /evalue="8.20E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="sylD"
                     /protein_end="179"
                     /protein_start="157"
                     /score="34.3"
                     /tool="antismash"
                     /translation="VHHIVFDGWSMQIFLSEVASAY"
     CDS_motif       7015..7062
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0004"
                     /evalue="2.50E+00"
                     /label="Cy4"
                     /locus_tag="sylD"
                     /protein_end="282"
                     /protein_start="266"
                     /score="1.6"
                     /tool="antismash"
                     /translation="RVTPYMVGLAAFSVLL"
     CDS_motif       7084..7173
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0005"
                     /evalue="4.00E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="sylD"
                     /protein_end="319"
                     /protein_start="289"
                     /score="44.9"
                     /tool="antismash"
                     /translation="DLVIGSPMSNRQSSDLEGVIGFFVNTLPNR"
     CDS_motif       7222..7341
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0006"
                     /evalue="6.80E-19"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="sylD"
                     /protein_end="375"
                     /protein_start="335"
                     /score="60.3"
                     /tool="antismash"
                     /translation="RASVLDTFEHAHVPFDQIVEAIQPPRSLSHAPVFQVLFDM"
     aSDomain        7678..8913
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylD_AMP-binding.1"
                     /evalue="4.20E-93"
                     /label="sylD_AMP-binding.1"
                     /locus_tag="sylD"
                     /protein_end="899"
                     /protein_start="487"
                     /score="304.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FKRSAAQWGEADALVYENRRYSYAQLDAEARVLAGHLHAAGVRRG
                     DRVAVVQRYGPEVIIALLAVHQVGGIYVPLAIDDARHADLLKDIEPRLVLTLSACQEQL
                     RGYPCLVQDDLPQATGTLHENEFEGRNTQPEDIAYIIFTSGSTGRPKGVSVSHGSWVSL
                     LQALEQTYGQTEPGVTGILQMANFTFDVFMSDVVRALAVGARLIMCPRQSLADPEQLYE
                     LITAERVTLLEFVPAVLRQMIRYLEETGRRLDTLRTLTCGADVWFVHEYRKMQTLCGPQ
                     TRVVSVYGVTEATCESATFEPDAGWYDPERSLPIGGPLPNTSLYLVDATLNLVPRTVPG
                     ELLIGGGAVASGYMNRPELNEKSFLTGSFSASGRFLPGVGEQRFYRTGDLCRHMRDGTI
                     EFLGRSDNQVKIR"
     CDS_motif       7864..7902
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0007"
                     /evalue="2.60E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="sylD"
                     /protein_end="562"
                     /protein_start="549"
                     /score="5.4"
                     /tool="antismash"
                     /translation="LAVHQVGGIYVPL"
     CDS_motif       8089..8148
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0008"
                     /evalue="1.40E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="sylD"
                     /protein_end="644"
                     /protein_start="624"
                     /score="29.9"
                     /tool="antismash"
                     /translation="AYIIFTSGSTGRPKGVSVSH"
     CDS_motif       8680..8769
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0009"
                     /evalue="1.10E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="sylD"
                     /protein_end="851"
                     /protein_start="821"
                     /score="33.7"
                     /tool="antismash"
                     /translation="PRTVPGELLIGGGAVASGYMNRPELNEKSF"
     CDS_motif       8878..8943
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0010"
                     /evalue="1.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="sylD"
                     /protein_end="909"
                     /protein_start="887"
                     /score="36.4"
                     /tool="antismash"
                     /translation="FLGRSDNQVKIRGFRIELGEVE"
     aSDomain        9226..9423
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylD_PCP.1"
                     /evalue="6.40E-24"
                     /label="sylD_PCP.1"
                     /locus_tag="sylD"
                     /protein_end="1069"
                     /protein_start="1003"
                     /score="75.9"
                     /tool="antismash"
                     /translation="EEQLVEDWQHLLNVPRVGIDDNFFESGGHSLLVTQVIAQIKKRFG
                     VALSIANLFEGPTVAQVAEKI"
     aSDomain        9505..10419
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylD_Condensation_LCL.2"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.00E-88"
                     /label="sylD_Condensation_LCL.2"
                     /locus_tag="sylD"
                     /protein_end="1401"
                     /protein_start="1096"
                     /score="288.1"
                     /tool="antismash"
                     /translation="RQRLSFAQRRLWLTQHSEPGTAYNMPEICRLTGQLDIPALEGALN
                     LLLERHEVLRTHFTRELETFVDTQGVTQKEPLVVTSHADSARVPFRLQTIAREALTAAL
                     EVEVHTPFVLDKELPIRALLLQTASDEHVLCLTLHHIAYDGWSSALLRQELAVFYRHLT
                     QGERITLSPLEAQYQDYAAWQRNQLETGAFTTQIDAWKASLQDLPPPLVLPVRSSPREG
                     NPLAGDYVALTLPGDCSARLDQLCLRLQCTPAMVMHAAFALLLHRYTGQDDILIGMPFS
                     GRDHDESTNLIGFFVNLLPLRLRL"
     aSModule        9505..12636
                     /complete
                     /domains="nrpspksdomains_sylD_Condensation_LCL.2"
                     /domains="nrpspksdomains_sylD_AMP-binding.2"
                     /domains="nrpspksdomains_sylD_PCP.2"
                     /locus_tags="sylD"
                     /monomer_pairings="Val -> Val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9517..9546
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0011"
                     /evalue="2.30E-01"
                     /label="C1_LCL_004-017"
                     /locus_tag="sylD"
                     /protein_end="1110"
                     /protein_start="1100"
                     /score="4.9"
                     /tool="antismash"
                     /translation="SFAQRRLWLT"
     CDS_motif       9565..9678
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0012"
                     /evalue="2.80E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="sylD"
                     /protein_end="1154"
                     /protein_start="1116"
                     /score="58.3"
                     /tool="antismash"
                     /translation="TAYNMPEICRLTGQLDIPALEGALNLLLERHEVLRTHF"
     CDS_motif       9916..9981
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0013"
                     /evalue="1.30E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="sylD"
                     /protein_end="1255"
                     /protein_start="1233"
                     /score="27.4"
                     /tool="antismash"
                     /translation="LHHIAYDGWSSALLRQELAVFY"
     CDS_motif       10030..10068
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0014"
                     /evalue="5.10E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="sylD"
                     /protein_end="1284"
                     /protein_start="1271"
                     /score="12.8"
                     /tool="antismash"
                     /translation="QYQDYAAWQRNQL"
     CDS_motif       10255..10305
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0015"
                     /evalue="3.20E-02"
                     /label="Cy4"
                     /locus_tag="sylD"
                     /protein_end="1363"
                     /protein_start="1346"
                     /score="7.5"
                     /tool="antismash"
                     /translation="CTPAMVMHAAFALLLHR"
     CDS_motif       10321..10410
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0016"
                     /evalue="6.70E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="sylD"
                     /protein_end="1398"
                     /protein_start="1368"
                     /score="41.0"
                     /tool="antismash"
                     /translation="DILIGMPFSGRDHDESTNLIGFFVNLLPLR"
     CDS_motif       10459..10572
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0017"
                     /evalue="9.10E-08"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="sylD"
                     /protein_end="1452"
                     /protein_start="1414"
                     /score="24.4"
                     /tool="antismash"
                     /translation="RQALLAAEANQSVPIDYLAQVLNPQRLPGKHPFFQAGL"
     aSDomain        10915..12084
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylD_AMP-binding.2"
                     /evalue="7.40E-95"
                     /label="sylD_AMP-binding.2"
                     /locus_tag="sylD"
                     /protein_end="1956"
                     /protein_start="1566"
                     /score="309.8"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEQRVRQTPQAIALQLQQRCWTYAELDRLANGIAHALIKKGVQAG
                     EHIGLFTGRHPYLVAGMLGILKARCAFVPLNPQDSMEGALGYMIKDAALHRVVGHRGLA
                     HELAALGLETLLVDDFEGDQREWSAPACQREPQDLAYILYTSGSTGQPKGVMVSQRNID
                     NTANAFARTLELTGQSRQLQYFSPVFDGVCGEVFPVLISGATLVFAASEQLLPGPDLVT
                     LLREQRITHLQITPTALRLLPHAELAELKVIISAGEACPANVAQTWAAGRRFLNGYGPT
                     ETTVYASARDYWDERGALVLRPLDNVRMYVLDRYLNPLPCGVPGELYIGGSGVAQGYLN
                     LDERTAQAFLPDPYGVSPEARLYRTGDFVVRQFNGSLSYVGRIDNQVKIR"
     CDS_motif       11101..11142
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0018"
                     /evalue="7.20E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="sylD"
                     /protein_end="1642"
                     /protein_start="1628"
                     /score="10.1"
                     /tool="antismash"
                     /translation="LGILKARCAFVPLN"
     CDS_motif       11332..11388
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0019"
                     /evalue="1.50E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="sylD"
                     /protein_end="1724"
                     /protein_start="1705"
                     /score="29.8"
                     /tool="antismash"
                     /translation="AYILYTSGSTGQPKGVMVS"
     CDS_motif       11872..11961
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0020"
                     /evalue="1.60E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="sylD"
                     /protein_end="1915"
                     /protein_start="1885"
                     /score="46.0"
                     /tool="antismash"
                     /translation="PCGVPGELYIGGSGVAQGYLNLDERTAQAF"
     CDS_motif       12049..12114
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0021"
                     /evalue="3.40E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="sylD"
                     /protein_end="1966"
                     /protein_start="1944"
                     /score="35.1"
                     /tool="antismash"
                     /translation="YVGRIDNQVKIRGFRIELGDVE"
     aSDomain        12439..12636
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylD_PCP.2"
                     /evalue="1.90E-18"
                     /label="sylD_PCP.2"
                     /locus_tag="sylD"
                     /protein_end="2140"
                     /protein_start="2074"
                     /score="58.3"
                     /tool="antismash"
                     /translation="TVRTIWQEVLDCQEIDSDDNFFDLGGHSLRIVETQKRLSELLQAP
                     VAMTDLFEYPTLRGLVAHLER"
     aSDomain        12712..13986
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylD_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="3.30E-150"
                     /label="sylD_PKS_KS.1"
                     /locus_tag="sylD"
                     /protein_end="2590"
                     /protein_start="2165"
                     /score="492.5"
                     /tool="antismash"
                     /translation="AVVGMAGRFPGAADLSEFWQNITEGVESTLYFSDEVMLAHGVYPD
                     LLERADFVKCGNRLEDVDKFDAEFFGFSPREAQLMDPQQRIFLQCAWAAMEAAGYGGAL
                     NDLRVGVFASASTSHYLLDHVYPRRQELQLENIQWLLGNGRDFMASRVAYKLNLAGPAI
                     TVETACSSSLVAVQMACESLLRGESDMVIVGGASVEAQYYGYQAAPGSIISVDGHCRPF
                     DAQASGTTGGSGCAVLVLKLADRAIEDRDHIHALIKGGAINNDGSSKVSYTAPSVHGQA
                     QVVSAALDAANISADSIGYVEAHGTGTRLGDPVEVRALTQAYTSALPHFTPGFCALGSL
                     KSNIGHLDAASGIAGLVKAILAVQHNVLPASLNFTRANPEIDFSDSPFYVNTTSRPWPA
                     AASPRRAGVSSFGIGGTNAHVIVEEP"
     aSModule        12712..18753
                     /complete
                     /domains="nrpspksdomains_sylD_PKS_KS.1"
                     /domains="nrpspksdomains_sylD_PKS_AT.1"
                     /domains="nrpspksdomains_sylD_PKS_DH2.1"
                     /domains="nrpspksdomains_sylD_PKS_KR.1"
                     /domains="nrpspksdomains_sylD_PCP.3"
                     /domains="nrpspksdomains_sylD_Thioesterase.1"
                     /final_module
                     /locus_tags="sylD"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       13189..13236
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0022"
                     /evalue="1.10E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="sylD"
                     /protein_end="2340"
                     /protein_start="2324"
                     /score="17.5"
                     /tool="antismash"
                     /translation="GPAITVETACSSSLVA"
     CDS_motif       13609..13656
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0023"
                     /evalue="4.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="sylD"
                     /protein_end="2480"
                     /protein_start="2464"
                     /score="12.5"
                     /tool="antismash"
                     /translation="YVEAHGTGTRLGDPVE"
     aSDomain        14275..15117
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylD_PKS_AT.1"
                     /evalue="1.70E-87"
                     /label="sylD_PKS_AT.1"
                     /locus_tag="sylD"
                     /protein_end="2967"
                     /protein_start="2686"
                     /score="285.4"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="MFSGQGSQYAGMFKGLYDSEAVFRQTVDRCAVILQRYGVDILACL
                     YPPAGSKTGDALSRTEIAQPALFVVEYACALLLQSRGIHPQALIGHSLGELVAACFAGV
                     YSVEDSLKLVVERGRLMQRQAPGAMLAVGLSEADCARFLEPGVELATVNGPLQCVLAGD
                     FEAIARVERQLAEEGLVGRVLDTSHAFHSRMMAPAAHALKAVVNGFSVQPPTIALVSNH
                     NGGWFSIDSSSQSDYWASHLLETVRFSDGIGLLADELEDPIFLEVGPGRALQSALKSYA
                     "
     CDS_motif       14278..14325
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0024"
                     /evalue="2.40E-04"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="sylD"
                     /protein_end="2703"
                     /protein_start="2687"
                     /score="13.9"
                     /tool="antismash"
                     /translation="FSGQGSQYAGMFKGLY"
     CDS_motif       14464..14499
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0025"
                     /evalue="4.90E-03"
                     /label="PKSI-AT-M_m2"
                     /locus_tag="sylD"
                     /protein_end="2761"
                     /protein_start="2749"
                     /score="10.0"
                     /tool="antismash"
                     /translation="QPALFVVEYACA"
     CDS_motif       14518..14640
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0026"
                     /evalue="1.60E-25"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="sylD"
                     /protein_end="2808"
                     /protein_start="2767"
                     /score="81.5"
                     /tool="antismash"
                     /translation="GIHPQALIGHSLGELVAACFAGVYSVEDSLKLVVERGRLMQ"
     CDS_motif       14722..14760
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0027"
                     /evalue="2.50E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="sylD"
                     /protein_end="2848"
                     /protein_start="2835"
                     /score="11.2"
                     /tool="antismash"
                     /translation="ATVNGPLQCVLAG"
     CDS_motif       14983..15018
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0028"
                     /evalue="1.60E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="sylD"
                     /protein_end="2934"
                     /protein_start="2922"
                     /score="12.0"
                     /tool="antismash"
                     /translation="YWASHLLETVRF"
     aSDomain        15421..16068
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylD_PKS_DH2.1"
                     /evalue="2.80E-29"
                     /label="sylD_PKS_DH2.1"
                     /locus_tag="sylD"
                     /protein_end="3284"
                     /protein_start="3068"
                     /score="94.0"
                     /tool="antismash"
                     /translation="WLVDEHRVFEGRPVLSGTGCVELVRNAYARMEGVESIELSDVYFP
                     TPLVLEDEQASQRVLITFKDHAESTEFFLESVSDEGNGPQQRTMLHAQGFIKRHDRERS
                     VPTALMQLQADHADCLADEVEHAALNTRLGLFGPRWKCFRSIWLSEDEGLALLELDQAF
                     AADVEHFALHPALLDMATGFLSIMENRARRLPFHYQRLTIHAPLRSRLYSHAR"
     aSDomain        16894..17433
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylD_PKS_KR.1"
                     /evalue="1.50E-52"
                     /label="sylD_PKS_KR.1"
                     /locus_tag="sylD"
                     /protein_end="3739"
                     /protein_start="3559"
                     /score="170.0"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTYVVTGGLGGMGLALASHLAAKAKAVTLVLMSRSATVTDEVGQA
                     LQALEQQGARIQHMAVDCADREAFTAALHQVRLQHGRISGAIHAAGVQASGLIQLSQAT
                     AWAQVMGSKVVGTDVLIEVLRQEPVDFIFLCSSLASVLGGLGQADYAAANAYLDARAQA
                     CRQEGIPVVSLNWDAWA"
     CDS_motif       16897..16998
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0029"
                     /evalue="1.50E-10"
                     /label="PKSI-KR_m1"
                     /locus_tag="sylD"
                     /protein_end="3594"
                     /protein_start="3560"
                     /score="33.6"
                     /tool="antismash"
                     /translation="TYVVTGGLGGMGLALASHLAAKAKAVTLVLMSRS"
     CDS_motif       17278..17385
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0030"
                     /evalue="9.00E-15"
                     /label="PKSI-KR_m4"
                     /locus_tag="sylD"
                     /protein_end="3723"
                     /protein_start="3687"
                     /score="47.2"
                     /tool="antismash"
                     /translation="VDFIFLCSSLASVLGGLGQADYAAANAYLDARAQAC"
     aSDomain        17695..17898
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylD_PCP.3"
                     /evalue="3.10E-20"
                     /label="sylD_PCP.3"
                     /locus_tag="sylD"
                     /protein_end="3894"
                     /protein_start="3826"
                     /score="64.0"
                     /tool="antismash"
                     /translation="EQEVAQLWQELLGGDMPGVLDNFFDLGGHSLLGSQLISRIRSRFQ
                     QCLTLAEFLDEPTIERIARSLGS"
     aSDomain        17980..18753
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sylD_Thioesterase.1"
                     /evalue="1.50E-29"
                     /label="sylD_Thioesterase.1"
                     /locus_tag="sylD"
                     /protein_end="4179"
                     /protein_start="3921"
                     /score="95.9"
                     /tool="antismash"
                     /translation="RPFFCLPGMGGNVNQVLGLAKAMGTQRPFYGLQCLGLDGKAEPHL
                     SVEDMAEHYIRCMKSVQAHGPYLLGGHSLGGKVAYEIARRLEARGDQVGLLALFDSAAP
                     PYTQMQVPTDAQVLGSLLSIFGHYFDKPIKLSREELQALEHLDDEEKIRYLKDTLESHG
                     LLDARGDEGSIRGLFNVYKAAAAFGMRYDPPKVALDASLVLFRAVDSMPSGINLPEIRD
                     TDAWGWESFSAAKVRTVDVSGDHFTCLSVHARQIAD"
     CDS_motif       18163..18237
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sylD_0031"
                     /evalue="1.70E-12"
                     /label="NRPS-te1"
                     /locus_tag="sylD"
                     /protein_end="4007"
                     /protein_start="3982"
                     /score="39.6"
                     /tool="antismash"
                     /translation="QAHGPYLLGGHSLGGKVAYEIARRL"
     gene            18862..20097
                     /gene="sylE"
     CDS             18862..20097
                     /codon_start=1
                     /db_xref="GOA:Q83Y47"
                     /db_xref="InterPro:IPR001411"
                     /db_xref="InterPro:IPR001958"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="UniProtKB/TrEMBL:Q83Y47"
                     /gene="sylE"
                     /gene_functions="resistance (resist) tet_MFS_efflux (Score:
                     275.3; E-value: 5e-84)"
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 83; E-value: 2.6e-25)"
                     /gene_kind="transport"
                     /product="putative syringolin A exporter"
                     /protein_id="CAD70196.1"
                     /transl_table=11
                     /translation="MSGGYSKGDTRPPMRFILLILGLDVLGIGLAIPVMPTLIATIWPS
                     STEHVSLALGVALTLYSAMQFLCAPLLGALSDCHGRRPILLLALAGMCLGNLMAGFAGS
                     LTVLLIGRAIAGITAANIATAMAYIADISEGEQRTHFYGAAGSVIAIALVFGPVIGGGL
                     ASYGPHLPFLVAGGLAAINLLYGYMRLPESLAAEHRRAFEWRRTNPFGSLRGLWSTQGL
                     RPYLLAATCSWFAYGIFQSCFVLANQMRYGWSMLEVSYALAALALGMAFAQRVLVRKLT
                     PIMSNQRIIVTGYACCLLGYGFYTAAASVWLTVVGMCFHAVGLIAEPALRSELSRHASA
                     GHQGELQGGLTSLLSLVGGVAPVIGALIFAGNVGSGQHVLWLGAPFLVSLLMYVLAIGC
                     IQRGRTSAAWNS"
     CDS             complement(20117..20830)
                     /codon_start=1
                     /db_xref="GOA:Q83Y46"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="UniProtKB/TrEMBL:Q83Y46"
                     /gene_functions="regulatory (smcogs) SMCOG1071:GntR family
                     transcriptional regulator (Score: 157.9; E-value: 5.1e-48)"
                     /gene_kind="regulatory"
                     /note="ORF7"
                     /product="hypothetical protein"
                     /protein_id="CAD70197.1"
                     /transl_table=11
                     /translation="MDYRKPSDRKSMHARIVQELGMQIVSGRFKPDEKLPAEALLCEEY
                     AVSRPVLREATRVLVAKGLVYSRPRVGTVVKARREWHLLDPDVLHWVMQSSPQNDFFNL
                     LTSVRAVIEPAVAALAAQHATDAEIESIHEAYLRMEAAPTPEDLLQPDLDFHSRIADAT
                     HNDLLAHLCNMLSLALREALKYSNKRPNLHELAMPRHKAILTAIQNRDALGARHASLVQ
                     LDDARNALSVVLGGG"
     CDS             complement(20926..>22119)
                     /codon_start=1
                     /db_xref="GOA:Q83Y45"
                     /db_xref="InterPro:IPR000581"
                     /db_xref="InterPro:IPR008279"
                     /db_xref="UniProtKB/TrEMBL:Q83Y45"
                     /note="ORF8; similar to dihydroxyacid dehydratase (ilvD)"
                     /product="hypothetical protein"
                     /protein_id="CAD70198.1"
                     /transl_table=11
                     /translation="MFLSAEAGMSRSAGTCNTMGTASTMACMAEALGTSLPHNAAIPAV
                     DSRRYVLAHMSGMRAVDMVREDLRLSKILTKAAFENAIRVNAAIGGSTNAVIHLKAIAG
                     RIGVDLDLDDWSRMGRGMPTIVDLQPSGRFLMEEFYYAGGLPAVLRRMNEARLLPNPDA
                     LTVNGKSIGENTCNSPIYGEDQVIRALDNPIRADGGICVLRGNLAPLGAVLKPSAATPA
                     LMQHRGRGVVFENFEMYKSRINDPDLDIDANSVMVLKNCGPKGYPGMAEVGNMGLPAKL
                     LAQGVTDMVRISDARMSGTAYGTVVLHVAPEAAAGGPLAVVKEGDWIELDCAGGRLHLD
                     IPEAELASRLADWQAPQQLLLGGYRQLYVDRVMQADQGCDFDFLVGCRGSEVPRHSH"
ORIGIN
        1 agtgatggca ctttcattgc gcggtgatac ggttggccat gaaaaaagca ccggcagaca
       61 aaagctggaa tgggagttcg aacagagtgc aagtgagcgg ggtgttcatc actataccta
      121 ttttttttat catcacgcgc cagcgttacg gcaacatggc tttgttctgg tcagcggtcc
      181 ggaggcaggg aaaaataata gtcattgcgc agagcggcag gacgtcgcgg atgcgatttg
      241 ggacgttgct tgctctgagc cactatttac tggtttactg aacaggccga catcatcaaa
      301 tgaccgcggc gaaatgatcg acgccggtac cacctctgac gggatgacgg cgttctacct
      361 cggcgaagag aaggcattca gtttactgcg gtttgcaaat aaagaaaccg gaacaggaag
      421 tacgcaaggc gagtacagtc ttgcggcaga ggtgaagtcg ctggttcgtg agtttcatca
      481 taagttgacg ggcctggtca tgggcgtcaa tgagtcggac gaaaccttca ctattacgga
      541 ccgtgaaaag gaggtgtaca tatggacagc catcggcaag acctgtaatg aaattgccgt
      601 cattctaaat atatccaaaa gaacggtaga ttttcatatt tccaatgtca tctcgaagtt
      661 gggtgtcaga accaaactcc aggcctgcat acaactgacc aagatgggaa ttttgtaagg
      721 ggtttttgga acccatgacg actgggttga gtggcgggcg ccaaggcagt caacgcgttg
      781 agtgagcctg gattcttctt gtgcgattcc gacacagcgc gaggccgatc ggaatgctca
      841 ttgaccccat ctggatgccc gcgcgatggc tatcggtcat cgccattcgt ggtctgcgta
      901 ccttcgcgcg ccgactgttc gcacagtgtc tgcggtgcag tgccgtacgg cgaatgacgt
      961 ctgttttgca ggcgataaat actcagtatc tggcgcatga ccgattgcgt atcgcgacga
     1021 cccgagatga tgccaccctt ggccagattg gcttcggcat agtcagggtc ttgcaggaga
     1081 atggagtgtg ccttgtgcag gttccagtag gggatgcctg cgaacaggtg atgggtcagg
     1141 tgcaggttgt ccccgtgcat gccgataaac agcctctccc accaggaggg aaaacggttg
     1201 cgggtgatac gcaaggcctc ctgctccctg ccgaataatc caaaatgttc agaaacttcc
     1261 gacagccagc cgatgacctg aaaggccgtc agataaggaa cgagccagaa catcaagtaa
     1321 ccgtacacgc ccgtggtggc atagaaaagc gagaataaaa cagcgtgtac cgcgatcagt
     1381 gtcagggctt tgcgagggga tttcaacagt gcgcccaacc gatgaatgac gaggtagcgc
     1441 aggtagctga atatattcag aaacagcacg gttctaagca ggtggttgaa catgaagtcg
     1501 aatcgatctt cggtcgcctg cagcccggat tcaatatagt aacgatagtc cgggtccttg
     1561 tcggcgtcac cgagatgatg gtgatgcatg tgcacatgcg aatgtcgata agcctcgtaa
     1621 tcctgaaaga tgggtaatcc ggtcaggtag tggccaatgg cataattgag gcggcggctt
     1681 tgggtcaggg ttaaatgggc tgcttcatga acgagagagg caagggcgcg ttgccgtgaa
     1741 ccgataatca gcacactgag ggggtaagca tacaatgacc attgggtgag tgcgacagcg
     1801 gaagctatga caagaacatc ccccgaccaa cccaatagcc atcgccagtt attcttttta
     1861 taaagacacg tcagttcaag ttttagtgca tttgtacagt gaaatcgttg gacggtctgc
     1921 atcgtttacc tcgacaggtt gtgctctgca atgcgttggt aattagggcg ttatatagac
     1981 tagagagggg cggggagccg cgtaagctgc tattttttac aggtagacag ttggcggtgg
     2041 cgtgtggtct ttttaaagaa gtcaatcacc gctaacaaaa acggatacac cggttttttt
     2101 acgaggttga tgtcacctga tcaatatgtt atccgaggcc gtcatgaaca gttttgagaa
     2161 aaataatacc gcaccgtcac gctctcaaga tctcgctatg cgggccggcg cacagcatat
     2221 aaccggtact gaagggccac tctccatgtc tcaggaacaa gcctggtttc ttgagacgtt
     2281 agtaccagag agtattgctt ataactttca ggccatgctg aacattcgcg gcaaccttga
     2341 tatcaacgtg cttgaacgtg cgctgaacag ggtggttgaa cgccatcagt cactgtccac
     2401 tgtttttgat gaggttgacg gagaaccacg gcaaactatc caggacgcct ggtccgtgaa
     2461 cattccgatc gttgacctgt ctgccagcag tgaagcggta cggcagacct acatgaattc
     2521 tattgtgaaa gctgaaattg cccagaagat cgaagtggcg aaacttccgc tgattcgctg
     2581 ggtactgttc aaattcagcg atcagttcca cgtattgctg catatcgaac accacctcat
     2641 tcatgacggc tggtcattcc ggctgtttct caaagagctg aatcattttt acaatgaaga
     2701 aaagggccgc gcgaatcagg agccccttga gccggtgatc cagttcatcg attactgcca
     2761 atgggagcgc gactggctgg attcggctga aggccgtcaa ggccgagact tctggtacgg
     2821 acgtcttgaa acctggccgg cctacacgca ttcgccgttt ccggcagaga aggacgcgca
     2881 agccgcattg gattttgtcg gaagttcggt gtcggtgccg ctgccgggta agttgatcag
     2941 cgcactgcag gcgtatgggt cggaaaataa atccaccctg ttcgagacca tgttttcgct
     3001 gtttgcctgc gtggtagcgg cgcgttcggg tcagacgcaa cagctgatag gcaccgccgt
     3061 cgccaaccgt gacttgccgg gcatcgaaaa caccatcggt atgctggtca acatgttgcc
     3121 gctgcgcatc gacattgatg cgaatacgtc ctgggcgcct ttactggcag ccgtgaaaga
     3181 agaaatccgc acggcttgcc tgcagtcgca tgtaccgttt tcaacaatgg ttgccgatct
     3241 gagtccggat cgtgtcactc agcaattgcc gtacatccag gttgctttca gctttcataa
     3301 ctccatgtcc cgcaccctgg actttgcgga cattgatgtc gaggtggtgg aagggctggc
     3361 aaacggttct gcgaaattcg acctcaacgt catttgcgtt ttcgatgacg aagtgaaccc
     3421 ggccgctggt ggtcgcttca tgcttgagta ctccaccgct gtcgccaaag aggcagatgt
     3481 cagagcgctg atggccgatt ttcttcacct ggctggcgcc tggctcgagc aacctgcaga
     3541 aagtctcgcc aatgtacgca aggctgctgt gctggccgcg ccgtcaggca gttcttctgt
     3601 caatcctggt gtggaattct ggaaacaatc actcgacctc gaagcttcgg ggcttctgcc
     3661 tgaccatgcg cttaatcgcg cagtcagcgg gccgcttgcg cgtcatgaaa tccctcttcc
     3721 ggatgaaagc cttgcgcgcc tgtttcaagc gtgtgagcag cgcaacattg aacctgaggc
     3781 agcgcttttt tctctctatg ccgtaaccat ggctcgttat ggcgggcatc aaaccgtcgt
     3841 ggccggtctg ggtactgctg ccgatggaca gcgtctggcc ataccgttgc cactcaagtt
     3901 gacgctcgct gcgcatgaca cgtttgccga tgtcttcctg cgcgcacaac agcactgcga
     3961 gcaggctcgt cactggcaca aatcttctgc ccagggtctg gaacaagcgc ttgatgacag
     4021 tgttgcggcc tcgggaagag cgccgcagtc attgatacag tcggtattct gcgacggtgt
     4081 ttccgcgcgt gcagagcagg gaggcgcgtc gggcagtctg cactcgcctc tcgaattcgt
     4141 cctggaccgt tccagcacaa aggcctcgtt gtcactcggc tatgctgctg atctgttcgc
     4201 tcaggaaaca gccacttcaa tggccgggca ttacgtccag ttgctggaaa aggccagcga
     4261 atcactggac gaaacgctgg cgcaaagtct atcggcccag caccaggctg ccattcagac
     4321 acagtgtgaa gggcttgact caagctatcc tgaaacgtcc ctgcacgcca tcgtcgaggc
     4381 ctttgcggcc acacagcccg aggccatcgc tgtgcggtgc ggcgatgcag tgctgacgta
     4441 cgctcagctc aatgaatccg ccgacaaagt tgccgacaca ttgcttcgca agggcgtgca
     4501 gccgggtgac gtcgtgggca tctgcatgat gcgctccgaa ttgctggttg cggcgctgtt
     4561 gggcgtgctc aaggccggtg catgctacct ctcgatcgac tgtgcattgc ctgcagagcg
     4621 tcgtaattgg cttctggagg aggcggacgt caagtgggca ctgatcgatg agagtgctcc
     4681 ggctttacgt gatgcaacct caacactgtt gatagggcag ttggtgaatg agcaggacga
     4741 cccacgcgtg tcgccgctgg ccaaacctgt catcagcgcg gatgctcgct gctattacat
     4801 gtttacatcg ggttccacgg gcactccgaa ggccacggcc agtacccacc gcgcggtggt
     4861 gagtctggtc aagggtacgg actatatcga tatcaagggt gacgaccgct tcctgttttt
     4921 cgcgcccctc gcgttcgatg cgtcgacctt tgaaatctgg ggcgccttgc tgaacggcgc
     4981 gcagttggtg gttcagcctg gcgaagccgg cggactggat gacctggcac acacactgga
     5041 aaatcagcag gtcagtgtgc tctggctgac gtccgcattg ttccaggaga tggtcgatca
     5101 atatcctcag gcgatggctg gcgtcaggca tgtactgacc ggcggtgacg ttgtttcgcc
     5161 gcaaagcatg cgcagtttgc tggcacgctc caccgggacg ctcaccatct gttacggccc
     5221 gactgaaggc acggtcttta ccacggccta cagcatggac aaggtcgaac aagtgactga
     5281 caaacccttg atcggatggc cgattgcaca ggccgatgcc tacatcgtgg atgttttcgg
     5341 gcagcttgcc gagcccggtg ttccagggga gttattcatc ggcggcacag ggatcaccgg
     5401 tgcctacctc aagcgtccgg aactgaacca ggagcggttt gtgacgctgg agcggttccc
     5461 cggcaaaaca ctcttccgca ccggtgatct ggcgcgctgg accccgggcc gcggtatcga
     5521 gttccttgga cgcagtgaca gtcagataaa gatccgtggc ttgcgtatag aaccgggtga
     5581 ggtcgagcag gcgatacgtc aattgccggg tgtcacagcg tgctcactga ttctgcgcac
     5641 attgaacctg gacaaacagc tggtcgcctt cgtcagtctg gacggaagcg ttgcactgga
     5701 tgagcaacag attcgtgtgg cgttgagaga atgcctgccc gactacatgg tgcctgccga
     5761 agtgcatgtg atcgagcaac tgccggtcaa tgcgagcggc aaggtcgaca agcgtgcctt
     5821 gcttgaactg gcgactcaaa acggccgtgc aagggttacc agcgagcgac cgtcgacggc
     5881 tctggaaaaa tccattgccg aggtctgggc gcacatcctc aacgtgccgg acgtgggtag
     5941 aaatgaagac ttcttctcca tcggcggaca ctcgttggcc ggtatgcgga tcatgtcgag
     6001 gctgagcaag caatttggca ctcgtctgtc gctgaatctg ctcttcgagt atcccagcgt
     6061 cgagacgctt gcaggtgcta tcgaacgctc ggccgagccg ttgacggcct gaccgttttt
     6121 caggcgcgtg gtgggtagca acagcacccc cacgcgcttt ctcacctctc agcctcccaa
     6181 tttaccttcc tcgcagcgac atcggtcgct gtcgaggtgg agatggtcat gtctcaaaaa
     6241 aagccggtca cttcaaccac cgagtccgct gtcaggatgc cgaccccggc agccgggggg
     6301 ttcctgaatt tatcgcctgc gcaaaaaagc ctctggttca tgcaccagat ggaagatgcc
     6361 agcgccacgt acaatgtgcc ttttgcgctg cgtattgacg gggcactgga tcgcgcggcc
     6421 ctcgagcggg cagtggacag tgtctatcag cgccagagtg cactgcgcta tcgttttccc
     6481 tgtatcgatg ggcagccggt gattcgcctt gtcgatgagc aactgctgat tcgcaaggtt
     6541 gacctgcgag ccgaaccgga cagcgaagcc gcgctgaaag cgttcgagca aagcgaagcg
     6601 cgttatgttt tcgatcttga gcatgaagcg cttctgcgcg cgacgttgct gcactgtgcg
     6661 accgacgagc atgttctgtt gatcaatgtt catcacatcg ttttcgacgg ttggtcgatg
     6721 cagatcttcc tctccgaagt ggcctcagcc tattcggcgc tggtgcgggg cagcgaggta
     6781 aacgcggagc cgttgaactt cgactttggc gattatttga gtctgagccc atcgaacgct
     6841 gaacgggctc ccgatatcga ccactggcag cggcgattgg ccggtgcgcc gccggtattg
     6901 ccattaccgc tggataacaa gcgtgcggcc gttcagcgtt acgcaggcca gcgttgtcat
     6961 tttcaagtgc ctgaagccgt ctcggacgcg ctgaaaaacc tggcaaggga gtgtcgcgtc
     7021 acgccctata tggtagggct cgcggccttt tccgtgctgc tgtatcgcta tacgcaagag
     7081 gcggatctgg tcatcggatc gccgatgtcg aatcggcagt cctctgacct ggaaggcgtg
     7141 atcggtttct tcgtcaatac gctgccaaac cggatcgatg catcgggttc tccttctttc
     7201 gtcgagttgc tcaaaagagt tcgtgcctcg gtgctcgata cgttcgagca tgcccatgtg
     7261 cccttcgatc agattgtcga ggccattcag cccccacgtt ccctgagcca tgcgccggtg
     7321 tttcaggtgc tgttcgatat ggccaacgaa gatttttcgg tcgagctgga aaacctgcgc
     7381 actcgtgttt atacgctcga ctcctgtacc gccaaatatg acctgagtct taccctggca
     7441 ctgacggcgc gcggcatgag cggcgcaatc gagtatgaca ccgcattgct ggatgagcgc
     7501 gcagtgcagg ggatgattga tagcctgctg atcattatgg agcaggtgtc gcgcaacccg
     7561 gacggggcca ttgacgattt ttcgctactg tcgtgcgaag ctgtggagca ggcgttgcgc
     7621 ctggccaatc atcagcccgc agcgccgcag gcgccctttg caccttttca tcaatggttc
     7681 aaacgcagtg ccgcgcagtg gggcgaggcg gatgcgctgg tctatgaaaa ccgtcgttac
     7741 agctatgcgc aactggatgc agaggcccgg gtactggcgg gccacctgca tgctgccggc
     7801 gttcggcgtg gtgaccgggt tgcagtggtg caacgctatg ggccagaggt catcatcgcg
     7861 ttactggcgg tgcatcaggt cgggggcatt tatgtgccgc tggcgatcga cgatgcccgt
     7921 catgctgatc tgctcaagga catcgagccc agactggtgc tcacactgag cgcctgtcag
     7981 gagcaactga ggggttatcc atgccttgtg caggatgatt tgccgcaggc caccggcaca
     8041 ctgcacgaga acgaattcga ggggcgcaac acacagccgg aagacatcgc ttacattatt
     8101 tttacctccg gttctaccgg gcgtcccaag ggcgtcagtg tctcccacgg cagttgggta
     8161 agtctgctcc aggcgctgga gcagacttac ggtcagaccg agccaggtgt caccggcatt
     8221 ttgcagatgg ccaatttcac gtttgacgta ttcatgagcg atgtggtccg cgcgctggcg
     8281 gttggcgcac ggttgataat gtgcccgcgg cagagtctgg ctgaccctga acaactctat
     8341 gagctgatca cggctgaacg ggtgacgttg ctcgagttcg tgccggcggt cctgcggcag
     8401 atgatacgtt acctggaaga gacgggacgg cgtctggata ccctgcgtac gctgacctgt
     8461 ggcgcggatg tctggttcgt ccacgagtat cggaaaatgc agacgctgtg tggaccgcag
     8521 accagggttg tcagtgttta cggagtcacc gaggcaacct gcgaaagcgc tacgttcgag
     8581 cccgatgcgg ggtggtatga ccctgagcgc agcttgccaa tcggcggtcc gttgccgaac
     8641 acgtccctgt acctggtcga cgcaacgctg aatctggtac cgcgcactgt ccccggcgaa
     8701 ttgttgattg gtggcggcgc agtggcgtcc ggttacatga atcgccctga actgaacgag
     8761 aaaagcttcc tgacaggttc gttctcggcc agcggacggt ttttacctgg cgtcggcgag
     8821 cagcggttct atcgcaccgg cgatctgtgt cggcacatgc gcgacggcac catcgagttt
     8881 ctgggccgca gtgacaacca ggtcaagatt cgtggcttcc gcatcgagtt gggggaagtc
     8941 gagagcgtac ttgccgacca tccggacgtg aatgaatgcg cggtggtgac ccgccagtca
     9001 ccaggcgctg aggccgagct gatcggttat gtacaaaccc gcgctacagc gcagcaactc
     9061 aatgcctacc ttggcgagcg cctgccgggc cacatggtgc cgcgcctgtt ggtggtcctg
     9121 gcggcactgc ccttgaccgc aaacggcaag atcgatcgca agagcctgcc ggagcccgac
     9181 tggacgcagg actcacgcgc ctatgccgca ccgcgtaaca gtctggaaga gcagcttgtc
     9241 gaagactggc aacacctgct caacgtgccg cgtgtgggca ttgacgacaa ttttttcgag
     9301 agtggcgggc attctctgct ggtcacccag gtcattgcgc agatcaaaaa acgctttggt
     9361 gtggcgctca gcattgccaa cctgttcgaa gggcctaccg tcgcccaggt cgccgaaaag
     9421 attatgctga gtatgatcca gatctcccaa ggggccagtg tcgcttccag gccggcggcg
     9481 atcggtcgca gcagcggtat cgagcgtcaa cgtctgtcgt ttgcccaacg ccgactgtgg
     9541 ttgacccagc acagtgaacc gggcactgcc tacaacatgc cggaaatatg ccggctgacc
     9601 gggcaactgg atattcctgc gctggaaggt gcattgaatc tgctgcttga gcgccatgaa
     9661 gtcttgcgca cgcatttcac ccgtgagctt gaaacgtttg tagacacgca gggcgtcacg
     9721 cagaaagagc cgttggttgt gacaagtcac gctgacagcg cacgtgtacc gttcaggctg
     9781 caaaccatcg ctcgcgaagc gctcacggct gcgctggagg tggaggtgca cacgccgttc
     9841 gtgctggaca aggaactgcc gatacgcgcg ttgcttctgc agacggcgtc ggatgagcat
     9901 gttctgtgcc tgacgctgca tcacatcgcc tacgacggct ggtcgagtgc cttgcttcgt
     9961 caggagctgg cagtgttcta tcggcacttg acgcaaggtg agcgcatcac actgagccca
    10021 ctggaggctc agtatcagga ctatgcggcc tggcaacgaa atcaactcga aaccggggcc
    10081 ttcacgactc aaatcgatgc ctggaaggca tcgctgcagg acttgccgcc gcctctggta
    10141 ctgcctgtac gttccagtcc gcgagaagga aatccgttgg ctggcgacta cgttgcgctg
    10201 actctgcctg gcgactgctc ggcaaggctc gatcagcttt gcctgcgtct gcaatgcacg
    10261 ccggccatgg tcatgcacgc cgcgttcgcg ctgctgttgc atcgctacac cgggcaggac
    10321 gacattttga tcggcatgcc attctcggga agggaccatg atgaaagtac gaacctgatc
    10381 gggtttttcg ttaacctgct tccgttacgg ctgcgtttgc gaggccctct gcgtgtggcg
    10441 caggttatcg aacagagtcg tcaggccctg cttgccgccg aggcaaatca gtcggtgccg
    10501 atcgattacc tggcgcaagt gctcaacccg cagcggctgc cgggcaagca tccttttttc
    10561 caggcaggcc tggtggtgca gagtacgacg gccgtaccgc ttagcttgcc gcacgtgaaa
    10621 tcggaagaaa tctccttggc ctccactgag gtgaagctgg acctgatgct ggagttgcgt
    10681 gctgtcaaag gcgaaggggt gagtggggta ttcaaatatc gcacgtcgct gttcgagcgt
    10741 tctgttatct cgggcatggc agggcatttc cagtgtctgc tggaaaatat gctggctaat
    10801 gacgagcaga ccgtcgcgca ggtgaagatg ctgtctgcaa ccgaacagca gaggctgatc
    10861 agccagttca acgatacggc gcgcgacttt ggcgatggcg atgtcgtcag ccgttttgaa
    10921 cagcgtgtac gtcagactcc ccaggctatt gcccttcagt tgcaacaacg ctgctggaca
    10981 tacgccgaac tggaccggtt agccaacggc atcgcccacg cgttgataaa gaagggtgtg
    11041 caagccggtg agcacatcgg cctgttcact ggacggcatc cctatctggt ggcaggcatg
    11101 cttggcatcc tcaaggcgcg ctgtgccttt gtccccttga atccgcagga ttcgatggaa
    11161 ggtgcgctgg gctacatgat caaagacgca gcattgcacc gcgtggtggg tcatcgaggc
    11221 ttggcacacg agcttgccgc tctggggctg gagacgttgc tggtcgacga cttcgaaggt
    11281 gaccagcgcg aatggtctgc tccggcctgc cagcgtgagc ctcaggatct ggcctacatt
    11341 ctttacacct ctggctcgac cgggcagccc aagggggtaa tggtttcgca gcgcaatatc
    11401 gataacactg cgaatgcatt tgcgcgaaca ctggaactga ctggtcagtc gcgccagctg
    11461 cagtactttt cgccagtctt cgacggggtt tgtggcgagg tgtttccggt actgatcagc
    11521 ggcgccacac tggtatttgc agcctctgaa cagctgctcc cggggccgga tctggtgacg
    11581 cttctgcgcg agcaacgtat cacccatctg cagatcacgc cgacggccct gcgcttgctc
    11641 ccccatgccg agcttgccga actgaaagtc atcatcagcg ccggtgaagc ctgtccggcc
    11701 aatgtcgccc agacctgggc agccggcaga cgtttcctca atggttacgg tccgaccgaa
    11761 accacggtgt atgcatctgc ccgggattac tgggatgaac gaggtgcctt ggtattgcgg
    11821 cctctggaca acgtcagaat gtatgtcctt gaccggtatc tgaaccctct tccctgcggt
    11881 gtacccggcg agctttacat tggcgggagc ggggtggcac agggttatct gaatctggat
    11941 gagcgcaccg cgcaagcgtt tcttcccgac ccatacggcg tttcgcccga ggcgcggctg
    12001 taccgcactg gcgactttgt cgtgcgtcag ttcaacggaa gcctgagcta tgtcgggcgt
    12061 atcgataatc aggtcaagat tcgcggtttt cgcattgagc tgggcgacgt cgaaacgcgc
    12121 ttgaacgcga tagccgggct ggagcaggcg gtcgtggtgg tcaaacagga tgaccagggg
    12181 cacaaggctc tggtggggta ttacgtcggc acaccgagcg tggcacaggt acgtgcagag
    12241 ctggccaggg tgctgccggc acatagtgtg ccggagcgtc ttgtctgctt gcccgagctg
    12301 ccgcttagcc gtactggcaa agtcgatcgc aagtcgctcg aaaatcgcgt tgatcagcgc
    12361 gctcaggaag gcactgcggt cgggacgccg gcgacccttc ctgcagccgt caggcctgct
    12421 ggaaaacgtc tgcacaacac ggtcagaacg atctggcagg aagtgctcga ttgccaggaa
    12481 atcgattcgg acgacaattt tttcgatctc ggtggccact cgttacgcat cgtcgagacg
    12541 caaaaacgtt tgagcgagct tttgcaggcg cccgtggcca tgacagacct tttcgaatac
    12601 ccgacgctgc gtggtctggt cgctcacctg gaacgcttgc atgggccgct gccggaggtt
    12661 ggccaagcca gcgaggcatc acctgccatt gatccaggga atcgcacgct ggcggtcgtc
    12721 ggcatggccg ggcgctttcc gggcgccgcc gacctgagcg agttctggca gaacatcacc
    12781 gaaggggtgg agtcgactct ttacttcagt gatgaggtca tgctcgcgca tggcgtatac
    12841 cctgatctgc tggagcgtgc cgatttcgtc aagtgtggca atcgtctcga ggacgtcgac
    12901 aagttcgatg ccgagttctt cggcttttca ccgcgtgaag cacagctgat ggatcctcag
    12961 cagcgtatct ttcttcaatg cgcgtgggcc gcgatggaag ccgccggtta cggcggcgct
    13021 ctgaacgatt tgcgtgtggg cgtatttgca agcgcgagca ccagccatta cctgctcgat
    13081 cacgtttacc cgaggcgcca ggagctgcaa ctggagaaca tccagtggtt gttgggtaat
    13141 ggccgcgatt tcatggcttc gcgtgtggct tacaaactca atctcgcggg acctgcgatt
    13201 accgtcgaaa cggcttgctc ctcgtcactg gtggcggtcc agatggcctg cgaaagcttg
    13261 ctgcgaggcg agtcggatat ggtgatcgtc ggcggtgctt cggtcgaagc tcaatactac
    13321 ggttaccagg cggcaccggg cagcatcatt tccgtcgatg gccattgccg gccgttcgat
    13381 gcccaggcca gtggcaccac tggcggcagc ggttgtgcag tgttggtcct caaactggct
    13441 gacagggcaa tcgaagatcg cgaccatatt catgccttga tcaagggcgg ggcgatcaat
    13501 aacgatggct ccagtaaggt cagttacacc gcgcccagtg ttcatgggca ggcccaggtg
    13561 gtgagcgctg cactcgatgc agcgaatatc agcgcagatt ccattggtta cgtcgaggcg
    13621 catggcaccg gcactcgtct gggtgacccg gtagaagtcc gtgcgctgac gcaggcctat
    13681 accagcgctt tgccacattt cacgccgggc ttttgtgccc ttggttcgtt gaagagcaac
    13741 atcggtcatc ttgatgcggc ctcaggcatc gccgggctgg tcaaagccat acttgccgtg
    13801 caacacaacg tgctgcctgc aagcctgaac ttcacgcggg ccaatcccga aatcgatttc
    13861 agcgacagcc cgttttatgt caacacgacc tccaggccgt ggccggcagc ggcctcgcca
    13921 cgtcgggcag gcgtcagctc cttcggcatc ggcgggacca atgcgcatgt cattgtcgag
    13981 gaacctcctc aaccgtcggt acgcccgcat gacgatagcg aacgctggta catactgccg
    14041 ttctctgcac gctccgcagc agcgctggat catcagcgtc ggcaactgat cacctgtctg
    14101 cagaatcccg cagccgatct acgcgatatc gccttcacgc tgggagaggg tcgtacacgt
    14161 tttgccttca gggacagcgt cgtcagccag agtattgccg gagccttgca cgcgctgcag
    14221 gcgccttcgt ccacagcgct aatggaacgc aggcaggacc gtccgatcgt gttcatgttc
    14281 tccgggcagg gcagccagta cgcgggaatg ttcaagggcc tctacgacag tgaggcagta
    14341 tttcggcaga cagttgaccg ctgtgcagtc atattgcagc gttatggcgt cgacattctg
    14401 gcctgtctgt acccgccagc gggtagcaaa acaggcgacg ccctgagccg gacggagatc
    14461 gcgcagccgg cactttttgt ggtcgagtac gcgtgcgccc tgttgttgca aagccgcggt
    14521 atccacccgc aggcgctcat aggccatagc cttggggagc tggtggctgc ctgttttgcc
    14581 ggggtctaca gtgttgaaga cagcttgaaa ctggttgtcg agcggggccg cctgatgcaa
    14641 cgtcaagcgc ccggtgcgat gcttgccgtt ggcctctcgg aagcagactg cgcgcgtttt
    14701 ctggagcccg gcgtggagct ggctaccgtc aatgggccgc tgcaatgtgt cctggcgggt
    14761 gattttgaag ccattgcgcg ggtcgagcga caactggccg aggaagggct cgtagggcgt
    14821 gtactggata cctcgcacgc ttttcattcc cgcatgatgg ctccagctgc gcacgcgttg
    14881 aaggccgttg ttaacgggtt ctctgttcag cccccgacta tcgcgctcgt gtccaaccac
    14941 aacggtggtt ggttctcgat cgattcgagc agccagagtg attattgggc gtctcatctg
    15001 ctggaaaccg tgcgcttttc tgacggtatc gggctgcttg ccgacgaact ggaagacccg
    15061 atttttctcg aagtcggccc gggccgtgct cttcagagtg cactgaaatc ctatgctgag
    15121 cccttgtgcg tgcttggttg cactcggcat gcacgggaca gccggtcgga cgaggcggca
    15181 ttggcgcaag gcatcgcgtc attgtggagg cagggggcac gtttcggttg ggcgcaggcc
    15241 acagggtgta cagacggcgc acgcgtgccg ctgccgacct atccgttcgc gcgggacagc
    15301 cactggatcg aggctgccgg gacggcttct tcagcgcagc acgaggcacc gttgttcctg
    15361 cattggcagc gtatgaatgg taatcgccgg cagttccggt tgagcctttc gccgcaactc
    15421 tggctggtgg acgaacaccg ggttttcgaa ggaaggccag tgctttccgg caccggatgc
    15481 gtcgaactgg tgcgcaatgc ctatgcgcgt atggaaggtg tcgagtcgat cgagctgagt
    15541 gatgtttact tcccgacacc tctggttctg gaagatgagc aggcctcgca acgcgtgctg
    15601 attacgttca aggatcacgc cgagagcacc gagtttttcc tcgagtcggt atcggacgag
    15661 ggtaacggtc cgcagcagcg cacgatgctg cacgcccagg gcttcatcaa gcgccacgac
    15721 cgggagcgtt ccgtacccac agcgttgatg cagcttcagg ccgaccatgc tgactgtctt
    15781 gccgatgaag tcgaacatgc ggcattgaac acgcgtctcg gcttgttcgg gcctcgctgg
    15841 aagtgctttc gttctatctg gcttagtgag gatgaggggt tggcgctcct ggaactcgat
    15901 caggcgtttg ccgctgatgt tgagcacttt gcgctgcatc cggcgttgct cgacatggcg
    15961 actggttttc tctcgatcat ggaaaaccgc gcccgcagat tgccgttcca ttaccagcgc
    16021 ctgactattc atgcaccact gcgctcccgg ctttacagcc acgcacggcg ggtccgcagt
    16081 aatgtttatg atgtgcaact gttcgaagtc gacagcgacg gcggagtcgg ggcgctgctg
    16141 gccgaggtga caggcttcac tttgcgcgag gagcgagtgg catcggaagc acagcgcact
    16201 gagcccctgg actggtgcca ggcgcctgca tggcgcccgg cattgccgcc gaggagcgac
    16261 tcgccattac aagggccctg gctggttgtg atgcgcggcg ttgcagccga taacagcatg
    16321 ctcttctcgc tgccgccgga cagtgtctgc atagcagatg ccggtgattc cggcactgcg
    16381 gtcgcgacaa ttgctcgcgg cgatgctcag gcgtatgagc aactgttcaa tacactggcg
    16441 gcgcaagatg ccttgccgag tcagatcatt tacatggctg gtcaggcgca accgacgcac
    16501 ggcgaacacg ctgccatcag gctgtttacc gatcttatgt cgctggtaca ggcgtacatc
    16561 cctcatgccg caaacaccac tgtgttgtca ctggtgaccg aaggtgcctg ccaggtggat
    16621 gacgatgagc cggtcaacag ctgtgtagcg accttgtctg gtgtggttcg cacacttgcg
    16681 tgggagctgc cacagattca gtgccgtcat ttcgatctgc cgcttgccaa tgcggcggag
    16741 aacgagacgc tgctgcttca ggcactccag cacatcgatc cagaccaggc atctccgctt
    16801 gcttcgaccc tggcgttgcg caaacagacg ttccatgagc cttgcctgcg agcgctgcaa
    16861 gtctcgccac cttcgcagcc gttcgaggag ggcgggacct acgtggttac cggtggtctg
    16921 ggcggcatgg ggcttgcgct ggccagtcat ctggctgcga aggcaaaagc cgtcacgtta
    16981 gtcctgatgt cccgttctgc gacagtcacg gatgaggtcg ggcaagcgct gcaggcgttg
    17041 gaacagcagg gcgcgcggat tcaacacatg gcggtcgatt gcgctgatcg cgaggctttc
    17101 actgcagcgc tgcaccaggt cagacttcag catggacgta tctctggagc catacacgcg
    17161 gcaggcgtgc aagccagcgg tctcattcaa ctgagccagg caactgcatg ggcacaggtc
    17221 atgggcagca aggtagtcgg caccgatgtg ctgatagagg ttttgcgcca ggaacctgtc
    17281 gatttcatat tcctgtgttc gtcgttggcg tcggtgctgg gtggtctggg ccaggcggat
    17341 tacgccgccg ccaacgctta cctggatgct cgggcgcagg cgtgtcgtca ggagggcata
    17401 cctgtggttt cgctcaactg ggatgcatgg gcgcaggcag gtatgcgtgt tgcctatgac
    17461 agggcacacc ccgagcaggc gccgattgac gatgtgcgcg ggctgaccaa cgcagaaggt
    17521 tgccagttgt tcgagctggc cctggcgcag aacacggctc aggtcatcgt gagcaaggcg
    17581 caggatctgc aacaactgat cgagcaactg cagcgcggcg gcgcgacatc ggctggccgt
    17641 gcaacaccgc tgttcgactc cggggccgag cgtgttgcgc cacgcaatgc ggtggaacag
    17701 gaagtcgcgc agttgtggca agagctgcta ggcggcgata tgccgggtgt gctggataac
    17761 ttcttcgatc tgggcgggca ctcgctgttg ggctcccagc ttatttcgcg aattcgttcg
    17821 cgctttcagc agtgcctgac gttggccgag tttctcgatg agccgaccat cgagcgaatc
    17881 gcccgttcat tgggcagtgg cgccgacgat acgcccatcg atgccgatga agccgccgtc
    17941 cgctactgtc tggtgccggt gcagcgaaac ggcgagggga gaccattctt ctgtctgccg
    18001 ggcatggggg gcaacgtcaa tcaagtgctt gggttggcca aggccatggg tacgcagcgg
    18061 cctttttacg gtctgcaatg ccttgggctc gatggcaagg ctgagcctca cctcagcgtc
    18121 gaggatatgg ccgaacacta tattcgctgc atgaaatcgg ttcaggcgca cgggccgtat
    18181 ctgttgggcg ggcattcact tggcggaaaa gtagcgtatg aaatcgccag gcgtctcgaa
    18241 gcgcgtggcg accaggtggg cttgctggcg ctgttcgact cggcggcacc tccctatacg
    18301 caaatgcagg tgcccactga tgctcaggta ctgggttcgc tgctgagtat cttcgggcat
    18361 tacttcgaca agccgatcaa gcttagccgc gaggagttgc aggcgctcga gcatctggat
    18421 gatgaggaaa agatccgcta cctgaaagac acactggaaa gtcacgggtt gctggatgcg
    18481 cgtggcgatg agggaagcat ccgggggctg ttcaacgtgt acaaggctgc tgccgcattc
    18541 ggtatgcgct atgacccgcc caaagttgcg cttgatgcct cgctggtgct gtttcgcgcg
    18601 gtcgactcga tgccctccgg catcaacctg cccgagatcc gcgacacgga tgcctggggc
    18661 tgggagtcgt tcagtgcggc gaaggtaaga acggtcgatg tctcgggaga ccactttacc
    18721 tgcctgtccg tccacgcccg gcaaattgcc gatgtattga tcgagcaact cgccgagtgt
    18781 gatcgataac ccgttctttg cggaacatgg cgagcaggct cagcgcctgc tcgcctacat
    18841 taatcagtct gaggtctaca tatgtctgga ggttactcaa aaggtgacac ccgtccaccc
    18901 atgcgcttca ttcttctgat attggggctc gatgtgcttg gcatcggtct ggcgatccct
    18961 gtcatgccga cgctgatcgc gactatctgg ccatcgtcta ccgagcatgt ctcgttggcg
    19021 ctgggtgtgg cgttgacact ttattcagcg atgcagtttc tgtgtgcgcc gctgctgggg
    19081 gcgctgagcg actgccatgg gcgtcgaccg atattgcttc tggcgctggc cggcatgtgc
    19141 ctgggcaatc tgatggctgg cttcgccggc agcctgacgg tcttgctgat aggccgtgcc
    19201 atcgcaggaa tcactgccgc caatatcgcc actgcgatgg cctatattgc ggacatcagt
    19261 gagggtgagc agcgcacgca tttctacggt gcagcgggca gtgtcatcgc catagcgctt
    19321 gttttcggcc cggtcatagg cgggggactt gcgtcttacg gaccgcactt gccctttctg
    19381 gtcgctggcg gcctggcggc aatcaacctg ctgtatggct acatgaggtt gccggaaagc
    19441 cttgcggccg agcatcggcg tgccttcgaa tggcggcgaa ccaacccgtt tggcagcctg
    19501 cgaggactct ggagtacgca aggcctgcgg ccgtatctgc tggctgcgac gtgctcctgg
    19561 ttcgcctacg ggatatttca aagctgcttt gtgctggcca atcagatgcg ttatggctgg
    19621 agcatgcttg aagtgtcgta cgcattggcg gcactcgctc tgggcatggc gttcgcgcag
    19681 cgcgtactgg tacgcaagct gacgccaatc atgtccaacc agcggatcat cgttacaggt
    19741 tatgcctgtt gcctgctggg ttatggtttc tatacggctg ctgcaagcgt ctggctgacg
    19801 gtggtgggca tgtgtttcca tgctgtcgga ctgatcgccg agccggcatt gcgcagtgag
    19861 ctctcgcgtc atgccagtgc agggcatcag ggcgagttgc agggcgggct gacatctctg
    19921 ttgagtctgg tgggcggtgt agcgccagtg attggcgccc tgatatttgc gggtaacgtt
    19981 ggctcaggcc agcatgtcct gtggctgggc gctccctttc tggtcagcct gttgatgtac
    20041 gtgctggcga taggctgcat ccagaggggg agaacttcag ccgcctggaa cagttgatcc
    20101 tcgcgctggt aacccatcag cctccgccga gcaccacact cagcgcgttg cgtgcatcgt
    20161 ccagttgcac cagcgaggcg tggcgtgcgc ccagcgcgtc gcggttctgg atggcggtga
    20221 ggatcgcctt gtgacgcggc atggccagtt cgtgcaggtt gggacgcttg ttggagtatt
    20281 tgagcgcttc gcgcaacgcc agtgacagca tgttgcacag gtgcgccagc aagtcgttgt
    20341 gggtggcgtc ggcgatgcgg ctgtggaagt cgagatcggg ttgcaacagg tcttccggcg
    20401 tcggtgcggc ttccatgcgc aggtaggctt cgtggatcga ctcgatctct gcgtcggtgg
    20461 catgctgcgc ggccagtgct gcaactgctg gttcgatgac agcgcgtacg ctggtcagca
    20521 gattgaagaa atcattctgc ggcgagcttt gcatgaccca gtgcagtacg tccgggtcca
    20581 gcagatgcca ttcgcgacgc gccttgacca ccgtgccgac acgcggccgc gaataaacca
    20641 gacccttggc caccagaacc cgcgtggctt cacgcaggac cgggcggctg acggcatact
    20701 cttcgcagag caacgcttcg gcaggcagct tttcgtcagg cttgaaacgg ccggacacga
    20761 tttgcatgcc cagttcctgg acaatacggg cgtgcatgct ttttcggtcg gaaggctttc
    20821 gataatccat gggaacgctg gtcggtcctg gcggtaattg ctgggcatca taccattgcg
    20881 taacacttgc ggcggctgcc tgcgtcaggc aaaccgccgc tttggtcagt gcgagtggcg
    20941 gggcacttcg gaacctctgc agccgaccag gaagtcgaaa tcacagccct gatccgcctg
    21001 catcacccgg tctacgtaca gttgacggta gccaccgagc aacagctgct gcggtgcctg
    21061 ccagtcggcg aggcgcgatg ccagttcggc ttccgggatg tccagatgca gacgcccgcc
    21121 agcgcagtcc agctcgatcc agtcgccttc cttgaccacc gccagcggtc cgcccgctgc
    21181 ggcttccggc gccacatgca gaaccacggt gccgtaagct gtgccgctca tgcgcgcatc
    21241 ggaaatgcgc accatgtcag tcacgccctg cgccagcagc ttggctggca agcccatgtt
    21301 gccgacctcg gccatgcccg gataaccctt ggggccgcag ttcttcagca ccatgaccga
    21361 gttggcatcg atgtccagat ccggatcgtt gatccgtgac ttgtacatct cgaaattctc
    21421 gaacaccact ccgcgtccac ggtgctgcat cagcgccggc gtcgcggccg agggcttgag
    21481 cacggcaccc agcggcgcga ggttgccgcg cagcacgcaa atcccgccgt cggcgcggat
    21541 cgggttgtcc agcgcgcgga tcacctgatc ttcgccatag atgggggagt tgcaggtgtt
    21601 ttcaccgatg cttttgccat tgacggtcaa ggcatccggg ttgggcagca gcctggcttc
    21661 gttcatgcgc cgcagcacgg cgggcaggcc accggcgtaa taaaactctt ccatcaggaa
    21721 gcgccccgaa ggttgcaggt cgacaatcgt cggcatgcca cggcccatgc gtgaccagtc
    21781 atccaggtcc aggtcgacgc cgatgcgtcc ggcgatggcc ttcaggtgaa tcacggcgtt
    21841 ggtcgagcca ccgatggccg cgttgacccg gatggcgttt tcgaatgcgg ccttggtgag
    21901 aatcttcgac aggcgcaggt cttcacggac catatcgacg gcgcgcatgc cggacatgtg
    21961 cgccagcacg taacgtcgcg aatccaccgc cggaatggcc gcgttgtgcg gcagcgaagt
    22021 gcccagcgct tcggccatgc aggccatggt cgaggccgtg cccatggtgt tgcaggtgcc
    22081 tgccgagcgc gacatgcctg cttcggcgga caggaattc
//
